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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72858498
log Bayes Factor = 17.8755
Chromosome 2   position 145,211,738  (GRCh37) Explore rs72858498 on Ensembl!
Variant rs72858498 is part of Cluster X0070

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.999 0.001 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.998 0.002 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.998 0.002 0.000
R10 Abdominal and pelvic pain
0.998 0.002 0.000
R10.1 Pain localised to upper abdomen
0.998 0.002 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.997 0.003 0.000
Chapter II Neoplasms
0.991 0.009 0.000
M45-M49 Spondylopathies
0.983 0.017 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.983 0.017 0.000
Chapter XX External causes of morbidity and mortality
0.983 0.017 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.981 0.019 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.979 0.021 0.000
Chapter XXI Factors influencing health status and contact with health services
0.972 0.028 0.000
M15-M19 Arthrosis
0.971 0.029 0.000
M19 Other arthrosis
0.969 0.031 0.000
M19.9 Arthrosis, unspecified
0.969 0.031 0.000
M47 Spondylosis
0.961 0.039 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.956 0.044 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.955 0.045 0.000
B35-B49 Mycoses
0.955 0.045 0.000
D60-D64 Aplastic and other anaemias
0.953 0.047 0.000
E10-E14 Diabetes mellitus
0.949 0.051 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.945 0.055 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.943 0.057 0.000
S40-S49 Injuries to the shoulder and upper arm
0.941 0.059 0.000
E70-E90 Metabolic disorders
0.941 0.059 0.000
B95-B98 Bacterial, viral and other infectious agents
0.934 0.066 0.000
D70 Agranulocytosis
0.933 0.067 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.933 0.067 0.000
M47.8 Other spondylosis
0.927 0.073 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.926 0.074 0.000
R79 Other abnormal findings of blood chemistry
0.924 0.076 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.921 0.079 0.000
R10.2 Pelvic and perineal pain
0.920 0.080 0.000
B37 Candidiasis
0.918 0.082 0.000
Chapter VI Diseases of the nervous system
0.917 0.083 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.915 0.085 0.000
E86 Volume depletion
0.914 0.086 0.000
Chapter VIII Diseases of the ear and mastoid process
0.910 0.090 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.908 0.092 0.000
D61 Other aplastic anaemias
0.902 0.098 0.000
R17 Unspecified jaundice
0.902 0.098 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.902 0.098 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.901 0.099 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.898 0.102 0.000
B99-B99 Other infectious diseases
0.898 0.102 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.897 0.103 0.000
M65-M68 Disorders of synovium and tendon
0.896 0.104 0.000
S70-S79 Injuries to the hip and thigh
0.896 0.104 0.000
D10-D36 Benign neoplasms
0.894 0.106 0.000
M05-M14 Inflammatory polyarthropathies
0.893 0.107 0.000
S60-S69 Injuries to the wrist and hand
0.893 0.107 0.000
B25-B34 Other viral diseases
0.892 0.108 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.889 0.111 0.000
T66-T78 Other and unspecified effects of external causes
0.888 0.111 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.884 0.116 0.000
B37.8 Candidiasis of other sites
0.881 0.119 0.000
A30-A49 Other bacterial diseases
0.878 0.122 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.878 0.122 0.000
E11 Non-insulin-dependent diabetes mellitus
0.878 0.122 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.876 0.124 0.000
M45 Ankylosing spondylitis
0.876 0.124 0.000
M47.82 Other spondylosis (Cervical region)
0.875 0.125 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.873 0.127 0.000
R12 Heartburn
0.868 0.132 0.000
D61.9 Aplastic anaemia, unspecified
0.865 0.135 0.000
W00-W19 Falls
0.864 0.136 0.000
A00-A09 Intestinal infectious diseases
0.862 0.138 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.860 0.140 0.000
H90-H95 Other disorders of ear
0.858 0.142 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.854 0.146 0.000
G90-G99 Other disorders of the nervous system
0.853 0.147 0.000
S80-S89 Injuries to the knee and lower leg
0.852 0.148 0.000
S42 Fracture of shoulder and upper arm
0.851 0.149 0.000
D72 Other disorders of white blood cells
0.848 0.152 0.000
R73 Elevated blood glucose level
0.847 0.152 0.000
M65 Synovitis and tenosynovitis
0.847 0.153 0.000
Z29 Need for other prophylactic measures
0.844 0.156 0.000
S90-S99 Injuries to the ankle and foot
0.841 0.159 0.000
C34 Malignant neoplasm of bronchus and lung
0.841 0.159 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.838 0.162 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.838 0.162 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.834 0.166 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.833 0.167 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.832 0.168 0.000
M50-M54 Other dorsopathies
0.831 0.169 0.000
Y86 Sequelae of other accidents
0.827 0.173 0.000
S10-S19 Injuries to the neck
0.827 0.173 0.000
Chapter X Diseases of the respiratory system
0.827 0.173 0.000
E00-E07 Disorders of thyroid gland
0.826 0.174 0.000
B99 Other and unspecified infectious diseases
0.825 0.175 0.000
E65-E68 Obesity and other hyperalimentation
0.824 0.176 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.819 0.181 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.816 0.184 0.000
D32 Benign neoplasm of meninges
0.815 0.185 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.814 0.186 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.813 0.187 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.813 0.187 0.000
D63.0 Anaemia in neoplastic disease
0.813 0.187 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.813 0.187 0.000
D23 Other benign neoplasms of skin
0.812 0.188 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.809 0.191 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.808 0.192 0.000
B34 Viral infection of unspecified site
0.806 0.194 0.000
R29.6 Tendency to fall, not elsewhere classified
0.805 0.195 0.000
D10 Benign neoplasm of mouth and pharynx
0.802 0.198 0.000
S00-S09 Injuries to the head
0.801 0.199 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.801 0.199 0.000
C64-C68 Malignant neoplasms of urinary tract
0.800 0.200 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.799 0.201 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.798 0.202 0.000
Z29.2 Other prophylactic chemotherapy
0.796 0.204 0.000
M47.86 Other spondylosis (Lumbar region)
0.795 0.205 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.795 0.205 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.793 0.206 0.000
C43 Malignant melanoma of skin
0.793 0.207 0.000
D55-D59 Haemolytic anaemias
0.793 0.207 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.792 0.208 0.000
Chapter XXII Codes for special purposes
0.792 0.208 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.792 0.208 0.000
D75 Other diseases of blood and blood-forming organs
0.791 0.209 0.000
E20-E35 Disorders of other endocrine glands
0.790 0.210 0.000
M19.94 Arthrosis, unspecified (Hand)
0.790 0.210 0.000
Z34 Supervision of normal pregnancy
0.789 0.211 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.788 0.212 0.000
Chapter IX Diseases of the circulatory system
0.786 0.214 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.786 0.214 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.784 0.216 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.783 0.217 0.000
M86-M90 Other osteopathies
0.782 0.218 0.000
Q60-Q64 Congenital malformations of the urinary system
0.781 0.219 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.780 0.220 0.000
E10 Insulin-dependent diabetes mellitus
0.780 0.220 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.779 0.221 0.000
R74 Abnormal serum enzyme levels
0.775 0.224 0.000
M47.9 Spondylosis, unspecified
0.775 0.225 0.000
D34 Benign neoplasm of thyroid gland
0.774 0.226 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.774 0.226 0.000
S64 Injury of nerves at wrist and hand level
0.773 0.227 0.000
Z35 Supervision of high-risk pregnancy
0.773 0.227 0.000
W20-W49 Exposure to inanimate mechanical forces
0.773 0.227 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.772 0.227 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.771 0.228 0.000
T79-T79 Certain early complications of trauma
0.771 0.229 0.000
S20-S29 Injuries to the thorax
0.770 0.229 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.770 0.230 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.768 0.231 0.000
E11.9 Without complications
0.768 0.232 0.000
S42.0 Fracture of clavicle
0.767 0.233 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.765 0.235 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.765 0.235 0.000
D32.0 Cerebral meninges
0.765 0.235 0.000
T78 Adverse effects, not elsewhere classified
0.764 0.236 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.764 0.236 0.000
M51 Other intervertebral disk disorders
0.763 0.237 0.000
M70-M79 Other soft tissue disorders
0.763 0.237 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.758 0.242 0.000
I30-I52 Other forms of heart disease
0.758 0.242 0.000
R76 Other abnormal immunological findings in serum
0.758 0.242 0.000
S72 Fracture of femur
0.758 0.242 0.000
R26 Abnormalities of gait and mobility
0.758 0.242 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.756 0.244 0.000
T86 Failure and rejection of transplanted organs and tissues
0.755 0.245 0.000
D72.8 Other specified disorders of white blood cells
0.754 0.246 0.000
A41 Other septicaemia
0.754 0.246 0.000
A04 Other bacterial intestinal infections
0.754 0.246 0.000
D22 Melanocytic naevi
0.753 0.247 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.753 0.247 0.000
R10.0 Acute abdomen
0.752 0.248 0.000
C34.1 Upper lobe, bronchus or lung
0.750 0.249 0.000
C44 Other malignant neoplasms of skin
0.750 0.250 0.000
M91-M94 Chondropathies
0.747 0.253 0.000
C60-C63 Malignant neoplasms of male genital organs
0.747 0.253 0.000
B34.9 Viral infection, unspecified
0.745 0.255 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.745 0.255 0.000
H90 Conductive and sensorineural hearing loss
0.744 0.255 0.000
D18 Haemangioma and lymphangioma, any site
0.743 0.257 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.742 0.258 0.000
X60-X84 Intentional self-harm
0.741 0.259 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.741 0.259 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.740 0.260 0.000
C34.9 Bronchus or lung, unspecified
0.739 0.260 0.000
M47.2 Other spondylosis with radiculopathy
0.739 0.261 0.000
R73.9 Hyperglycaemia, unspecified
0.739 0.261 0.000
D73 Diseases of spleen
0.739 0.261 0.000
V20-V29 Motorcycle rider injured in transport accident
0.738 0.262 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.738 0.262 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.737 0.263 0.000
E11.5 With peripheral circulatory complications
0.737 0.263 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.735 0.264 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.735 0.265 0.000
C45 Mesothelioma
0.735 0.265 0.000
Y43 Primarily systemic agents
0.735 0.265 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.733 0.267 0.000
S01 Open wound of head
0.731 0.269 0.000
D23.4 Skin of scalp and neck
0.728 0.272 0.000
M47.1 Other spondylosis with myelopathy
0.727 0.273 0.000
T68 Hypothermia
0.727 0.273 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.727 0.273 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.726 0.274 0.000
V80-V89 Other land transport accidents
0.726 0.274 0.000
Z22 Carrier of infectious disease
0.726 0.274 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.726 0.274 0.000
S71 Open wound of hip and thigh
0.725 0.274 0.000
E13 Other specified diabetes mellitus
0.725 0.275 0.000
Q80-Q89 Other congenital malformations
0.724 0.276 0.000
E16 Other disorders of pancreatic internal secretion
0.724 0.276 0.000
B37.3 Candidiasis of vulva and vagina
0.723 0.277 0.000
Z60 Problems related to social environment
0.723 0.277 0.000
E50-E64 Other nutritional deficiencies
0.723 0.277 0.000
C32 Malignant neoplasm of larynx
0.721 0.279 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.721 0.279 0.000
M46 Other inflammatory spondylopathies
0.721 0.279 0.000
H92 Otalgia and effusion of ear
0.721 0.279 0.000
B35 Dermatophytosis
0.720 0.280 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.719 0.281 0.000
M10 Gout
0.718 0.282 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.717 0.283 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.717 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.717 0.283 0.000
B65-B83 Helminthiases
0.717 0.283 0.000
B50-B64 Protozoal diseases
0.717 0.283 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.717 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.717 0.283 0.000
A80-A89 Viral infections of the central nervous system
0.717 0.283 0.000
A75-A79 Rickettsioses
0.717 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.717 0.283 0.000
A65-A69 Other spirochaetal diseases
0.717 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.717 0.283 0.000
A15-A19 Tuberculosis
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.717 0.283 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.716 0.284 0.000
J30-J39 Other diseases of upper respiratory tract
0.716 0.284 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.284 0.000
H91 Other hearing loss
0.716 0.284 0.000
E40-E46 Malnutrition
0.715 0.284 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.715 0.285 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.715 0.285 0.000
Z04 Examination and observation for other reasons
0.714 0.286 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.712 0.288 0.000
Y52 Agents primarily affecting the cardiovascular system
0.711 0.288 0.000
R10.4 Other and unspecified abdominal pain
0.711 0.289 0.000
D16 Benign neoplasm of bone and articular cartilage
0.711 0.289 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.711 0.289 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.711 0.289 0.000
Z36 Antenatal screening
0.708 0.291 0.000
G30-G32 Other degenerative diseases of the nervous system
0.708 0.292 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.708 0.292 0.000
S42.00 Fracture of clavicle (closed)
0.708 0.292 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.707 0.293 0.000
M19.0 Primary arthrosis of other joints
0.707 0.293 0.000
M65.3 Trigger finger
0.707 0.293 0.000
Y57 Other and unspecified drugs and medicaments
0.706 0.294 0.000
C44.4 Skin of scalp and neck
0.706 0.294 0.000
M19.1 Posttraumatic arthrosis of other joints
0.705 0.295 0.000
S40 Superficial injury of shoulder and upper arm
0.705 0.295 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.705 0.295 0.000
M49 Spondylopathies in diseases classified elsewhere
0.705 0.295 0.000
T87 Complications peculiar to reattachment and amputation
0.705 0.295 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.705 0.295 0.000
Z32 Pregnancy examination and test
0.705 0.295 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.705 0.295 0.000
Y35-Y36 Legal intervention and operations of war
0.705 0.295 0.000
Y10-Y34 Event of undetermined intent
0.705 0.295 0.000
Y00-Y09 Assault
0.705 0.295 0.000
X85-X99 Assault
0.705 0.295 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.705 0.295 0.000
X50-X57 Overexertion, travel and privation
0.705 0.295 0.000
X30-X39 Exposure to forces of nature
0.705 0.295 0.000
X20-X29 Contact with venomous animals and plants
0.705 0.295 0.000
X10-X19 Contact with heat and hot substances
0.705 0.295 0.000
X00-X09 Exposure to smoke, fire and flames
0.705 0.295 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.705 0.295 0.000
W75-W84 Other accidental threats to breathing
0.705 0.295 0.000
W65-W74 Accidental drowning and submersion
0.705 0.295 0.000
W50-W64 Exposure to animate mechanical forces
0.705 0.295 0.000
V98-V99 Other and unspecified transport accidents
0.705 0.295 0.000
V95-V97 Air and space transport accidents
0.705 0.295 0.000
V90-V94 Water transport accidents
0.705 0.295 0.000
V70-V79 Bus occupant injured in transport accident
0.705 0.295 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.705 0.295 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.705 0.295 0.000
V40-V49 Car occupant injured in transport accident
0.705 0.295 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.705 0.295 0.000
V01-V09 Pedestrian injured in transport accident
0.705 0.295 0.000
B15-B19 Viral hepatitis
0.705 0.295 0.000
M06 Other rheumatoid arthritis
0.705 0.295 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.703 0.297 0.000
R77 Other abnormalities of plasma proteins
0.703 0.297 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.703 0.297 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.703 0.297 0.000
R71 Abnormality of red blood cells
0.703 0.297 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.702 0.298 0.000
D74 Methaemoglobinaemia
0.702 0.298 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.702 0.298 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.702 0.298 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.702 0.298 0.000
H65-H75 Diseases of middle ear and mastoid
0.700 0.300 0.000
M11 Other crystal arthropathies
0.700 0.300 0.000
E66 Obesity
0.700 0.300 0.000
M47.89 Other spondylosis (Site unspecified)
0.699 0.301 0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis
0.697 0.303 0.000
S43.0 Dislocation of shoulder joint
0.697 0.303 0.000
A40 Streptococcal septicaemia
0.696 0.304 0.000
M15 Polyarthrosis
0.696 0.304 0.000
M19.8 Other specified arthrosis
0.695 0.305 0.000
M19.2 Other secondary arthrosis
0.695 0.305 0.000
E14 Unspecified diabetes mellitus
0.695 0.305 0.000
I44 Atrioventricular and left bundle-branch block
0.694 0.306 0.000
M07 Psoriatic and enteropathic arthropathies
0.694 0.306 0.000
J95-J99 Other diseases of the respiratory system
0.694 0.306 0.000
M80-M85 Disorders of bone density and structure
0.693 0.306 0.000
R27 Other lack of coordination
0.693 0.307 0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.693 0.307 0.000
R16.1 Splenomegaly, not elsewhere classified
0.692 0.308 0.000
R25 Abnormal involuntary movements
0.692 0.308 0.000
Z74 Problems related to care-provider dependency
0.692 0.308 0.000
S79 Other and unspecified injuries of hip and thigh
0.692 0.308 0.000
W06 Fall involving bed
0.691 0.309 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.689 0.311 0.000
R11 Nausea and vomiting
0.688 0.312 0.000
D23.6 Skin of upper limb, including shoulder
0.688 0.312 0.000
R79.0 Abnormal level of blood mineral
0.687 0.313 0.000
S72.0 Fracture of neck of femur
0.686 0.314 0.000
Q00-Q07 Congenital malformations of the nervous system
0.685 0.315 0.000
I49 Other cardiac arrhythmias
0.685 0.315 0.000
W13 Fall from, out of or through building or structure
0.685 0.315 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.685 0.315 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.685 0.315 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.685 0.315 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.685 0.315 0.000
B48 Other mycoses, not elsewhere classified
0.685 0.315 0.000
B47 Mycetoma
0.685 0.315 0.000
B46 Zygomycosis
0.685 0.315 0.000
B45 Cryptococcosis
0.685 0.315 0.000
B44 Aspergillosis
0.685 0.315 0.000
B43 Chromomycosis and phaeomycotic abscess
0.685 0.315 0.000
B42 Sporotrichosis
0.685 0.315 0.000
B41 Paracoccidioidomycosis
0.685 0.315 0.000
B40 Blastomycosis
0.685 0.315 0.000
B39 Histoplasmosis
0.685 0.315 0.000
B38 Coccidioidomycosis
0.685 0.315 0.000
B36 Other superficial mycoses
0.685 0.315 0.000
B49 Unspecified mycosis
0.685 0.315 0.000
A04.8 Other specified bacterial intestinal infections
0.684 0.316 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.684 0.316 0.000
E11.4 With neurological complications
0.684 0.316 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.683 0.316 0.000
D10.1 Tongue
0.681 0.319 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.681 0.319 0.000
E11.2 With renal complications
0.681 0.319 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.681 0.319 0.000
I05-I09 Chronic rheumatic heart diseases
0.681 0.319 0.000
E12 Malnutrition-related diabetes mellitus
0.680 0.320 0.000
Z31 Procreative management
0.678 0.322 0.000
D10.3 Other and unspecified parts of mouth
0.678 0.322 0.000
L60-L75 Disorders of skin appendages
0.676 0.324 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.676 0.324 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.676 0.324 0.000
Q61 Cystic kidney disease
0.676 0.324 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.676 0.324 0.000
J40-J47 Chronic lower respiratory diseases
0.676 0.324 0.000
S48 Traumatic amputation of shoulder and upper arm
0.675 0.325 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.675 0.325 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.675 0.325 0.000
S44 Injury of nerves at shoulder and upper arm level
0.675 0.325 0.000
S41 Open wound of shoulder and upper arm
0.675 0.325 0.000
S47 Crushing injury of shoulder and upper arm
0.675 0.325 0.000
M79.8 Other specified soft tissue disorders
0.675 0.325 0.000
E85 Amyloidosis
0.674 0.326 0.000
E84 Cystic fibrosis
0.674 0.326 0.000
E79 Disorders of purine and pyrimidine metabolism
0.674 0.326 0.000
E77 Disorders of glycoprotein metabolism
0.674 0.326 0.000
E76 Disorders of glycosaminoglycan metabolism
0.674 0.326 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.674 0.326 0.000
E74 Other disorders of carbohydrate metabolism
0.674 0.326 0.000
E73 Lactose intolerance
0.674 0.326 0.000
E72 Other disorders of amino-acid metabolism
0.674 0.326 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.674 0.326 0.000
E70 Disorders of aromatic amino-acid metabolism
0.674 0.326 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.674 0.326 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.674 0.326 0.000
B37.0 Candidal stomatitis
0.674 0.326 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.674 0.326 0.000
S81 Open wound of lower leg
0.673 0.327 0.000
R15 Faecal incontinence
0.673 0.327 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.672 0.327 0.000
S01.0 Open wound of scalp
0.671 0.329 0.000
S92 Fracture of foot, except ankle
0.671 0.329 0.000
Y44 Agents primarily affecting blood constituents
0.670 0.329 0.000
C71 Malignant neoplasm of brain
0.670 0.330 0.000
W07 Fall involving chair
0.670 0.330 0.000
G95 Other diseases of spinal cord
0.670 0.330 0.000
G93 Other disorders of brain
0.670 0.330 0.000
R79.9 Abnormal finding of blood chemistry, unspecified
0.669 0.330 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.669 0.331 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.669 0.331 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.669 0.331 0.000
C15-C26 Malignant neoplasms of digestive organs
0.668 0.332 0.000
M40-M43 Deforming dorsopathies
0.666 0.334 0.000
M51.8 Other specified intervertebral disk disorders
0.666 0.334 0.000
D11 Benign neoplasm of major salivary glands
0.666 0.334 0.000
B25 Cytomegaloviral disease
0.665 0.335 0.000
C43.3 Malignant melanoma of other and unspecified parts of face
0.665 0.335 0.000
E88 Other metabolic disorders
0.665 0.335 0.000
G70-G73 Diseases of myoneural junction and muscle
0.665 0.335 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.664 0.335 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.664 0.335 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.664 0.335 0.000
M47.84 Other spondylosis (Thoracic region)
0.664 0.335 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.664 0.335 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.664 0.335 0.000
Z34.8 Supervision of other normal pregnancy
0.664 0.336 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.664 0.336 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.664 0.336 0.000
G82 Paraplegia and tetraplegia
0.663 0.337 0.000
S64.4 Injury of digital nerve of other finger
0.663 0.337 0.000
G20-G26 Extrapyramidal and movement disorders
0.662 0.338 0.000
C44.2 Skin of ear and external auricular canal
0.662 0.338 0.000
T85.2 Mechanical complication of intraocular lens
0.661 0.339 0.000
M05 Seropositive rheumatoid arthritis
0.661 0.339 0.000
S91 Open wound of ankle and foot
0.660 0.339 0.000
A02 Other Salmonella infections
0.660 0.340 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.660 0.340 0.000
Q35-Q37 Cleft lip and cleft palate
0.660 0.340 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.660 0.340 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.660 0.340 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.659 0.341 0.000
E06 Thyroiditis
0.659 0.341 0.000
D23.1 Skin of eyelid, including canthus
0.659 0.341 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.658 0.342 0.000
B37.9 Candidiasis, unspecified
0.658 0.342 0.000
B37.7 Candidal septicaemia
0.658 0.342 0.000
B37.6 Candidal endocarditis
0.658 0.342 0.000
B37.5 Candidal meningitis
0.658 0.342 0.000
B37.4 Candidiasis of other urogenital sites
0.658 0.342 0.000
B37.2 Candidiasis of skin and nail
0.658 0.342 0.000
B37.1 Pulmonary candidiasis
0.658 0.342 0.000
S14 Injury of nerves and spinal cord at neck level
0.658 0.342 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.658 0.342 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.657 0.343 0.000
V10-V19 Pedal cyclist injured in transport accident
0.656 0.343 0.000
S42.2 Fracture of upper end of humerus
0.656 0.344 0.000
E87.6 Hypokalaemia
0.656 0.344 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.656 0.344 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.656 0.344 0.000
C31 Malignant neoplasm of accessory sinuses
0.656 0.344 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.656 0.344 0.000
C37 Malignant neoplasm of thymus
0.656 0.344 0.000
C33 Malignant neoplasm of trachea
0.656 0.344 0.000
R90.0 Intracranial space-occupying lesion
0.656 0.344 0.000
E10.4 With neurological complications
0.655 0.345 0.000
D23.2 Skin of ear and external auricular canal
0.655 0.345 0.000
L40-L45 Papulosquamous disorders
0.655 0.345 0.000
S10 Superficial injury of neck
0.655 0.345 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.654 0.346 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.654 0.346 0.000
T91 Sequelae of injuries of neck and trunk
0.654 0.346 0.000
H72 Perforation of tympanic membrane
0.654 0.346 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.654 0.346 0.000
Z76 Persons encountering health services in other circumstances
0.653 0.347 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.651 0.349 0.000
Z28 Immunisation not carried out
0.651 0.349 0.000
Z27 Need for immunisation against combinations of infectious diseases
0.651 0.349 0.000
Z26 Need for immunisation against other single infectious diseases
0.651 0.349 0.000
Z25 Need for immunisation against other single viral diseases
0.651 0.349 0.000
Z24 Need for immunisation against certain single viral diseases
0.651 0.349 0.000
Z23 Need for immunisation against single bacterial diseases
0.651 0.349 0.000
Z20 Contact with and exposure to communicable diseases
0.651 0.349 0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status
0.651 0.349 0.000
Z13 Special screening examination for other diseases and disorders
0.649 0.351 0.000
Z35.5 Supervision of elderly primigravida
0.648 0.352 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.648 0.352 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.648 0.352 0.000
W19 Unspecified fall
0.648 0.352 0.000
D59 Acquired haemolytic anaemia
0.648 0.352 0.000
E28 Ovarian dysfunction
0.647 0.353 0.000
D61.8 Other specified aplastic anaemias
0.646 0.353 0.000
D61.3 Idiopathic aplastic anaemia
0.646 0.353 0.000
D61.2 Aplastic anaemia due to other external agents
0.646 0.353 0.000
D61.1 Drug-induced aplastic anaemia
0.646 0.353 0.000
D61.0 Constitutional aplastic anaemia
0.646 0.353 0.000
I50 Heart failure
0.646 0.354 0.000
C90.0 Multiple myeloma
0.646 0.354 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.646 0.354 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.646 0.354 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.646 0.354 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.646 0.354 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.645 0.355 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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