TreeWAS – Variant ID: rs72877580

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.134	0.866
# Top node	0.130	0.870
Chapter XIV Diseases of the genitourinary system	0.129	0.871
M20-M25 Other joint disorders	0.125	0.875
Chapter I Certain infectious and parasitic diseases	0.125	0.875
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.121	0.879
B95-B98 Bacterial, viral and other infectious agents	0.121	0.879
M70-M79 Other soft tissue disorders	0.121	0.879
M15-M19 Arthrosis	0.120	0.880
M25 Other joint disorders, not elsewhere classified	0.119	0.881
N40-N51 Diseases of male genital organs	0.119	0.881
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.118	0.882
N17-N19 Renal failure	0.115	0.885
M17 Gonarthrosis [arthrosis of knee]	0.115	0.885
D70-D77 Other diseases of blood and blood-forming organs	0.114	0.886
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.113	0.887
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.112	0.888
M17.9 Gonarthrosis, unspecified	0.111	0.889
N30-N39 Other diseases of urinary system	0.110	0.890
N50 Other disorders of male genital organs	0.109	0.891
Chapter XII Diseases of the skin and subcutaneous tissue	0.109	0.891
Chapter XV Pregnancy, childbirth and the puerperium	0.108	0.892
Chapter II Neoplasms	0.108	0.892
N60-N64 Disorders of breast	0.108	0.892
M65-M68 Disorders of synovium and tendon	0.107	0.893
D70 Agranulocytosis	0.107	0.893
Chapter VII Diseases of the eye and adnexa	0.107	0.893
M45-M49 Spondylopathies	0.106	0.894
M25.7 Osteophyte	0.105	0.895
N10-N16 Renal tubulo-interstitial diseases	0.104	0.896
M75 Shoulder lesions	0.104	0.896
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.103	0.897
M25.5 Pain in joint	0.103	0.897
N50.8 Other specified disorders of male genital organs	0.102	0.898
N18 Chronic renal failure	0.101	0.899
N32 Other disorders of bladder	0.101	0.899
S00-S09 Injuries to the head	0.099	0.901
N25-N29 Other disorders of kidney and ureter	0.099	0.901
M31 Other necrotising vasculopathies	0.097	0.903
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.096	0.904
M91-M94 Chondropathies	0.096	0.904
M86-M90 Other osteopathies	0.096	0.904
M60-M63 Disorders of muscles	0.096	0.904
M40-M43 Deforming dorsopathies	0.096	0.904
M00-M03 Infectious arthropathies	0.096	0.904
M79 Other soft tissue disorders, not elsewhere classified	0.096	0.904
Chapter VIII Diseases of the ear and mastoid process	0.096	0.904
M05-M14 Inflammatory polyarthropathies	0.096	0.904
M75.4 Impingement syndrome of shoulder	0.096	0.904
B97 Viral agents as the cause of diseases classified to other chapters	0.095	0.904
M25.4 Effusion of joint	0.095	0.905
A00-A09 Intestinal infectious diseases	0.095	0.905
N00-N08 Glomerular diseases	0.095	0.905
B35-B49 Mycoses	0.095	0.905
N42 Other disorders of prostate	0.093	0.907
M80-M85 Disorders of bone density and structure	0.093	0.907
M77 Other enthesopathies	0.093	0.907
Chapter XXII Codes for special purposes	0.093	0.907
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.093	0.907
Chapter XVI Certain conditions originating in the perinatal period	0.093	0.907
D50-D53 Nutritional anaemias	0.093	0.907
N99-N99 Other disorders of the genitourinary system	0.093	0.907
M20 Acquired deformities of fingers and toes	0.093	0.907
H30-H36 Disorders of choroid and retina	0.093	0.907
H40-H42 Glaucoma	0.092	0.907
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.092	0.908
N41 Inflammatory diseases of prostate	0.092	0.908
B25-B34 Other viral diseases	0.091	0.908
N48 Other disorders of penis	0.091	0.908
M25.56 Pain in joint (Lower leg)	0.091	0.909
M35 Other systemic involvement of connective tissue	0.091	0.909
N70-N77 Inflammatory diseases of female pelvic organs	0.091	0.909
Chapter XX External causes of morbidity and mortality	0.091	0.909
S01 Open wound of head	0.090	0.910
N18.3 Chronic kidney disease, stage 3	0.090	0.910
M50-M54 Other dorsopathies	0.090	0.910
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.090	0.910
M34 Systemic sclerosis	0.090	0.910
M33 Dermatopolymyositis	0.090	0.910
M32 Systemic lupus erythematosus	0.090	0.910
M30 Polyarteritis nodosa and related conditions	0.090	0.910
M24 Other specific joint derangements	0.090	0.910
M22 Disorders of patella	0.090	0.910
M21 Other acquired deformities of limbs	0.090	0.910
B99-B99 Other infectious diseases	0.090	0.910
B90-B94 Sequelae of infectious and parasitic diseases	0.090	0.910
B85-B89 Pediculosis, acariasis and other infestations	0.090	0.910
B65-B83 Helminthiases	0.090	0.910
B50-B64 Protozoal diseases	0.090	0.910
B20-B24 Human immunodeficiency virus [HIV] disease	0.090	0.910
B15-B19 Viral hepatitis	0.090	0.910
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.090	0.910
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.090	0.910
A80-A89 Viral infections of the central nervous system	0.090	0.910
A75-A79 Rickettsioses	0.090	0.910
A70-A74 Other diseases caused by chlamydiae	0.090	0.910
A65-A69 Other spirochaetal diseases	0.090	0.910
A50-A64 Infections with a predominantly sexual mode of transmission	0.090	0.910
A20-A28 Certain zoonotic bacterial diseases	0.090	0.910
A15-A19 Tuberculosis	0.090	0.910
L20-L30 Dermatitis and eczema	0.090	0.910
O94-O99 Other obstetric conditions, not elsewhere classified	0.090	0.910
M25.77 Osteophyte (Ankle and foot)	0.089	0.911
N64 Other disorders of breast	0.089	0.911
M65 Synovitis and tenosynovitis	0.088	0.911
N17 Acute renal failure	0.088	0.912
D00-D09 In situ neoplasms	0.088	0.912
N61 Inflammatory disorders of breast	0.088	0.912
D73 Diseases of spleen	0.088	0.912
M72 Fibroblastic disorders	0.088	0.912
N13 Obstructive and reflux uropathy	0.088	0.912
N32.8 Other specified disorders of bladder	0.087	0.912
M17.1 Other primary gonarthrosis	0.087	0.913
S20-S29 Injuries to the thorax	0.087	0.913
D80-D89 Certain disorders involving the immune mechanism	0.087	0.913
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.087	0.913
D55-D59 Haemolytic anaemias	0.087	0.913
D60-D64 Aplastic and other anaemias	0.087	0.913
M47 Spondylosis	0.087	0.913
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.087	0.913
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.087	0.913
M76 Enthesopathies of lower limb, excluding foot	0.087	0.913
M73 Soft tissue disorders in diseases classified elsewhere	0.087	0.913
M71 Other bursopathies	0.087	0.913
M70 Soft tissue disorders related to use, overuse and pressure	0.087	0.913
A30-A49 Other bacterial diseases	0.087	0.913
M25.74 Osteophyte (Hand)	0.087	0.913
S90-S99 Injuries to the ankle and foot	0.086	0.913
N60 Benign mammary dysplasia	0.086	0.913
M18 Arthrosis of first carpometacarpal joint	0.086	0.914
M15 Polyarthrosis	0.086	0.914
S50-S59 Injuries to the elbow and forearm	0.086	0.914
M25.9 Joint disorder, unspecified	0.085	0.914
M25.8 Other specified joint disorders	0.085	0.914
M25.6 Stiffness of joint, not elsewhere classified	0.085	0.914
M25.3 Other instability of joint	0.085	0.914
M25.2 Flail joint	0.085	0.914
M25.1 Fistula of joint	0.085	0.914
M25.0 Haemarthrosis	0.085	0.914
N51 Disorders of male genital organs in diseases classified elsewhere	0.085	0.914
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.085	0.914
N45 Orchitis and epididymitis	0.085	0.914
N46 Male infertility	0.085	0.914
N44 Torsion of testis	0.085	0.914
D10-D36 Benign neoplasms	0.085	0.915
N47 Redundant prepuce, phimosis and paraphimosis	0.085	0.915
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.085	0.915
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.085	0.915
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.085	0.915
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.085	0.915
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.085	0.915
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.085	0.915
L60-L75 Disorders of skin appendages	0.085	0.915
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.085	0.915
S60-S69 Injuries to the wrist and hand	0.085	0.915
N19 Unspecified renal failure	0.084	0.916
N40 Hyperplasia of prostate	0.084	0.916
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.084	0.916
M19 Other arthrosis	0.083	0.917
H43-H45 Disorders of vitreous body and globe	0.083	0.917
S80-S89 Injuries to the knee and lower leg	0.083	0.917
C64-C68 Malignant neoplasms of urinary tract	0.082	0.917
M17.5 Other secondary gonarthrosis	0.082	0.918
M17.4 Other secondary gonarthrosis, bilateral	0.082	0.918
M17.3 Other posttraumatic gonarthrosis	0.082	0.918
M17.2 Posttraumatic gonarthrosis, bilateral	0.082	0.918
C43-C44 Melanoma and other malignant neoplasms of skin	0.082	0.918
H40 Glaucoma	0.082	0.918
S70-S79 Injuries to the hip and thigh	0.082	0.918
N32.9 Bladder disorder, unspecified	0.082	0.918
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.082	0.918
D75 Other diseases of blood and blood-forming organs	0.082	0.918
D74 Methaemoglobinaemia	0.082	0.918
D72 Other disorders of white blood cells	0.082	0.918
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.082	0.918
D71 Functional disorders of polymorphonuclear neutrophils	0.082	0.918
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.081	0.918
T79-T79 Certain early complications of trauma	0.081	0.918
T66-T78 Other and unspecified effects of external causes	0.081	0.918
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.081	0.918
T33-T35 Frostbite	0.081	0.918
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.081	0.918
T26-T28 Burns and corrosions confined to eye and internal organs	0.081	0.918
T20-T25 Burns and corrosions of external body surface, specified by site	0.081	0.918
T15-T19 Effects of foreign body entering through natural orifice	0.081	0.918
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.081	0.918
T00-T07 Injuries involving multiple body regions	0.081	0.918
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.081	0.918
S10-S19 Injuries to the neck	0.081	0.918
N32.0 Bladder-neck obstruction	0.081	0.919
M79.6 Pain in limb	0.080	0.919
S40-S49 Injuries to the shoulder and upper arm	0.080	0.919
C15-C26 Malignant neoplasms of digestive organs	0.080	0.920
D17 Benign lipomatous neoplasm	0.080	0.920
L00-L08 Infections of the skin and subcutaneous tissue	0.079	0.920
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.079	0.921
N30 Cystitis	0.079	0.921
D37-D48 Neoplasms of uncertain or unknown behaviour	0.079	0.921
N37 Urethral disorders in diseases classified elsewhere	0.079	0.921
N36 Other disorders of urethra	0.079	0.921
N34 Urethritis and urethral syndrome	0.079	0.921
N33 Bladder disorders in diseases classified elsewhere	0.079	0.921
N50.1 Vascular disorders of male genital organs	0.079	0.921
T36-T50 Poisoning by drugs, medicaments and biological substances	0.079	0.921
N50.9 Disorder of male genital organs, unspecified	0.078	0.922
N50.0 Atrophy of testis	0.078	0.922
M20.1 Hallux valgus (acquired)	0.078	0.922
M25.46 Effusion of joint (Lower leg)	0.078	0.922
L50-L54 Urticaria and erythema	0.078	0.922
L10-L14 Bullous disorders	0.078	0.922
M23 Internal derangement of knee	0.078	0.922
O80-O84 Delivery	0.078	0.922
O85-O92 Complications predominantly related to the puerperium	0.078	0.922
O20-O29 Other maternal disorders predominantly related to pregnancy	0.078	0.922
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.078	0.922
L80-L99 Other disorders of the skin and subcutaneous tissue	0.078	0.922
N20-N23 Urolithiasis	0.078	0.922
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.078	0.922
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.078	0.922
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.078	0.922
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.078	0.922
C40-C41 Malignant neoplasms of bone and articular cartilage	0.078	0.922
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.078	0.922
N28 Other disorders of kidney and ureter, not elsewhere classified	0.077	0.922
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.077	0.923
H35 Other retinal disorders	0.077	0.923
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.077	0.923
M67 Other disorders of synovium and tendon	0.077	0.923
M66 Spontaneous rupture of synovium and tendon	0.077	0.923
M25.55 Pain in joint (Pelvic region and thigh)	0.077	0.923
H55-H59 Other disorders of eye and adnexa	0.077	0.923
H46-H48 Disorders of optic nerve and visual pathways	0.077	0.923
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.077	0.923
H10-H13 Disorders of conjunctiva	0.077	0.923
L40-L45 Papulosquamous disorders	0.077	0.923
M75.0 Adhesive capsulitis of shoulder	0.077	0.923
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.077	0.923
S01.8 Open wound of other parts of head	0.077	0.923
M31.6 Other giant cell arteritis	0.077	0.923
S02 Fracture of skull and facial bones	0.077	0.923
H33 Retinal detachments and breaks	0.077	0.923
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.076	0.924
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.076	0.924
L30 Other dermatitis	0.076	0.924
H53-H54 Visual disturbances and blindness	0.076	0.924
M49 Spondylopathies in diseases classified elsewhere	0.076	0.924
M46 Other inflammatory spondylopathies	0.076	0.924
M45 Ankylosing spondylitis	0.076	0.924
N18.9 Chronic renal failure, unspecified	0.076	0.924
M06 Other rheumatoid arthritis	0.076	0.924
C51-C58 Malignant neoplasms of female genital organs	0.076	0.924
N62 Hypertrophy of breast	0.076	0.924
M25.79 Osteophyte (Site unspecified)	0.075	0.924
M25.78 Osteophyte (Other)	0.075	0.924
M25.76 Osteophyte (Lower leg)	0.075	0.924
M25.75 Osteophyte (Pelvic region and thigh)	0.075	0.924
M25.73 Osteophyte (Forearm)	0.075	0.924
M25.72 Osteophyte (Upper arm)	0.075	0.924
M25.71 Osteophyte (Shoulder region)	0.075	0.924
M25.70 Osteophyte (Multiple sites)	0.075	0.924
H40.9 Glaucoma, unspecified	0.075	0.924
M17.0 Primary gonarthrosis, bilateral	0.075	0.924
N13.3 Other and unspecified hydronephrosis	0.075	0.925
N64.5 Other signs and symptoms in breast	0.075	0.925
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.074	0.925
N15 Other renal tubulo-interstitial diseases	0.074	0.925
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.074	0.925
N11 Chronic tubulo-interstitial nephritis	0.074	0.925
N10 Acute tubulo-interstitial nephritis	0.074	0.925
M75.8 Other shoulder lesions	0.074	0.925
M75.9 Shoulder lesion, unspecified	0.074	0.925
M75.5 Bursitis of shoulder	0.074	0.925
M75.3 Calcific tendinitis of shoulder	0.074	0.925
M75.2 Bicipital tendinitis	0.074	0.925
M48 Other spondylopathies	0.074	0.926
S01.1 Open wound of eyelid and periocular area	0.074	0.926
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.074	0.926
M25.59 Pain in joint (Site unspecified)	0.074	0.926
M25.58 Pain in joint (Other)	0.074	0.926
M25.57 Pain in joint (Ankle and foot)	0.074	0.926
M25.54 Pain in joint (Hand)	0.074	0.926
M25.53 Pain in joint (Forearm)	0.074	0.926
M25.52 Pain in joint (Upper arm)	0.074	0.926
M25.50 Pain in joint (Multiple sites)	0.074	0.926
N43 Hydrocele and spermatocele	0.074	0.926
M77.1 Lateral epicondylitis	0.074	0.926
M47.9 Spondylosis, unspecified	0.073	0.927
O00-O08 Pregnancy with abortive outcome	0.073	0.927
B37 Candidiasis	0.073	0.927
D50 Iron deficiency anaemia	0.073	0.927
N18.8 Other chronic renal failure	0.073	0.927
N18.5 Chronic kidney disease, stage 5	0.073	0.927
N18.4 Chronic kidney disease, stage 4	0.073	0.927
N18.2 Chronic kidney disease, stage 2	0.073	0.927
N18.1 Chronic kidney disease, stage 1	0.073	0.927
N18.0 End-stage renal disease	0.073	0.927
N32.4 Rupture of bladder, nontraumatic	0.073	0.927
N32.2 Vesical fistula, not elsewhere classified	0.073	0.927
N32.1 Vesicointestinal fistula	0.073	0.927
C60-C63 Malignant neoplasms of male genital organs	0.073	0.927
N42.9 Disorder of prostate, unspecified	0.072	0.927
N32.3 Diverticulum of bladder	0.072	0.928
O36 Maternal care for other known or suspected foetal problems	0.072	0.928
O34 Maternal care for known or suspected abnormality of pelvic organs	0.072	0.928
N35 Urethral stricture	0.072	0.928
N70 Salpingitis and oophoritis	0.072	0.928
M65.9 Synovitis and tenosynovitis, unspecified	0.072	0.928
S01.0 Open wound of scalp	0.072	0.928
O42 Premature rupture of membranes	0.072	0.928
N41.9 Inflammatory disease of prostate, unspecified	0.072	0.928
D05 Carcinoma in situ of breast	0.071	0.928
H90-H95 Other disorders of ear	0.071	0.928
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.071	0.929
A08 Viral and other specified intestinal infections	0.071	0.929
S08 Traumatic amputation of part of head	0.071	0.929
S07 Crushing injury of head	0.071	0.929
S06 Intracranial injury	0.071	0.929
S05 Injury of eye and orbit	0.071	0.929
S04 Injury of cranial nerves	0.071	0.929
S03 Dislocation, sprain and strain of joints and ligaments of head	0.071	0.929
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.071	0.929
N27 Small kidney of unknown cause	0.071	0.929
N25 Disorders resulting from impaired renal tubular function	0.071	0.929
N26 Unspecified contracted kidney	0.071	0.929
N60.8 Other benign mammary dysplasias	0.071	0.929
D35 Benign neoplasm of other and unspecified endocrine glands	0.071	0.929
M25.51 Pain in joint (Shoulder region)	0.071	0.929
N03 Chronic nephritic syndrome	0.070	0.930
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.070	0.930
N42.8 Other specified disorders of prostate	0.070	0.930
N48.8 Other specified disorders of penis	0.070	0.930
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.070	0.930
D17.9 Benign lipomatous neoplasm, unspecified	0.070	0.930
M31.9 Necrotising vasculopathy, unspecified	0.070	0.930
M31.8 Other specified necrotising vasculopathies	0.070	0.930
M31.7 Microscopic polyangiitis	0.070	0.930
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.070	0.930
M31.4 Aortic arch syndrome [Takayasu]	0.070	0.930
M31.3 Wegener's granulomatosis	0.070	0.930
M31.2 Lethal midline granuloma	0.070	0.930
M31.1 Thrombotic microangiopathy	0.070	0.930
M31.0 Hypersensitivity angiitis	0.070	0.930
C50-C50 Malignant neoplasm of breast	0.070	0.930
O47 False labour	0.070	0.930
N17.9 Acute renal failure, unspecified	0.070	0.930
C43 Malignant melanoma of skin	0.070	0.930
H65-H75 Diseases of middle ear and mastoid	0.069	0.930
D73.0 Hyposplenism	0.069	0.931
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.069	0.931
M02 Reactive arthropathies	0.069	0.931
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.069	0.931
M00 Pyogenic arthritis	0.069	0.931
M43 Other deforming dorsopathies	0.069	0.931
M42 Spinal osteochondrosis	0.069	0.931
M41 Scoliosis	0.069	0.931
M40 Kyphosis and lordosis	0.069	0.931
M63 Disorders of muscle in diseases classified elsewhere	0.069	0.931
M62 Other disorders of muscle	0.069	0.931
M61 Calcification and ossification of muscle	0.069	0.931
M60 Myositis	0.069	0.931
M90 Osteopathies in diseases classified elsewhere	0.069	0.931
M89 Other disorders of bone	0.069	0.931
M88 Paget's disease of bone [osteitis deformans]	0.069	0.931
M87 Osteonecrosis	0.069	0.931
M86 Osteomyelitis	0.069	0.931
M94 Other disorders of cartilage	0.069	0.931
M93 Other osteochondropathies	0.069	0.931
M92 Other juvenile osteochondrosis	0.069	0.931
M91 Juvenile osteochondrosis of hip and pelvis	0.069	0.931
M99 Biomechanical lesions, not elsewhere classified	0.069	0.931
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.069	0.931
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.069	0.931
M79.9 Soft tissue disorder, unspecified	0.069	0.931
M79.7 Fibromyalgia	0.069	0.931
M79.5 Residual foreign body in soft tissue	0.069	0.931
M79.4 Hypertrophy of (infrapatellar) fat pad	0.069	0.931
M79.3 Panniculitis, unspecified	0.069	0.931
M79.2 Neuralgia and neuritis, unspecified	0.069	0.931
M79.1 Myalgia	0.069	0.931
M79.0 Rheumatism, unspecified	0.069	0.931
M51 Other intervertebral disk disorders	0.069	0.931
S00 Superficial injury of head	0.069	0.931
H80-H83 Diseases of inner ear	0.069	0.931
H60-H62 Diseases of external ear	0.069	0.931
M14 Arthropathies in other diseases classified elsewhere	0.069	0.931
M12 Other specific arthropathies	0.069	0.931
M11 Other crystal arthropathies	0.069	0.931
M09 Juvenile arthritis in diseases classified elsewhere	0.069	0.931
M08 Juvenile arthritis	0.069	0.931
M07 Psoriatic and enteropathic arthropathies	0.069	0.931
M05 Seropositive rheumatoid arthritis	0.069	0.931
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.069	0.931
B97.6 Parvovirus as the cause of diseases classified to other chapters	0.069	0.931
B97.5 Reovirus as the cause of diseases classified to other chapters	0.069	0.931
B97.4 Respiratory synctial virus as the cause of diseases classified to other chapters	0.069	0.931
B97.3 Retrovirus as the cause of diseases classified to other chapters	0.069	0.931
B97.2 Coronavirus as the cause of diseases classified to other chapters	0.069	0.931
B97.1 Enterovirus as the cause of diseases classified to other chapters	0.069	0.931
B97.0 Adenovirus as the cause of diseases classified to other chapters	0.069	0.931
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.069	0.931
M25.49 Effusion of joint (Site unspecified)	0.068	0.931
M25.48 Effusion of joint (Other)	0.068	0.931
M25.47 Effusion of joint (Ankle and foot)	0.068	0.931
M25.45 Effusion of joint (Pelvic region and thigh)	0.068	0.931
M25.44 Effusion of joint (Hand)	0.068	0.931
M25.43 Effusion of joint (Forearm)	0.068	0.931
M25.42 Effusion of joint (Upper arm)	0.068	0.931
M25.41 Effusion of joint (Shoulder region)	0.068	0.931
M25.40 Effusion of joint (Multiple sites)	0.068	0.931
A07 Other protozoal intestinal diseases	0.068	0.931
A06 Amoebiasis	0.068	0.931
A05 Other bacterial foodborne intoxications	0.068	0.931
A03 Shigellosis	0.068	0.931
A02 Other Salmonella infections	0.068	0.931
A01 Typhoid and paratyphoid fevers	0.068	0.931
A00 Cholera	0.068	0.931
A04 Other bacterial intestinal infections	0.068	0.932
N08 Glomerular disorders in diseases classified elsewhere	0.068	0.932
N07 Hereditary nephropathy, not elsewhere classified	0.068	0.932
N06 Isolated proteinuria with specified morphological lesion	0.068	0.932
N05 Unspecified nephritic syndrome	0.068	0.932
N04 Nephrotic syndrome	0.068	0.932
N02 Recurrent and persistent haematuria	0.068	0.932
N01 Rapidly progressive nephritic syndrome	0.068	0.932
N00 Acute nephritic syndrome	0.068	0.932
B48 Other mycoses, not elsewhere classified	0.068	0.932
B47 Mycetoma	0.068	0.932
B46 Zygomycosis	0.068	0.932
B45 Cryptococcosis	0.068	0.932
B44 Aspergillosis	0.068	0.932
B43 Chromomycosis and phaeomycotic abscess	0.068	0.932
B42 Sporotrichosis	0.068	0.932
B41 Paracoccidioidomycosis	0.068	0.932
B40 Blastomycosis	0.068	0.932
B39 Histoplasmosis	0.068	0.932
B38 Coccidioidomycosis	0.068	0.932
B36 Other superficial mycoses	0.068	0.932
B35 Dermatophytosis	0.068	0.932
B49 Unspecified mycosis	0.068	0.932
M79.66 Pain in limb (Lower leg)	0.068	0.932
M65.3 Trigger finger	0.068	0.932
C90 Multiple myeloma and malignant plasma cell neoplasms	0.068	0.932
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.068	0.932
O32 Maternal care for known or suspected malpresentation of foetus	0.068	0.932
N48.6 Balanitis xerotica obliterans	0.068	0.932
S27 Injury of other and unspecified intrathoracic organs	0.068	0.932
L72 Follicular cysts of skin and subcutaneous tissue	0.068	0.932
B34 Viral infection of unspecified site	0.067	0.933
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.067	0.933
C83 Diffuse non-Hodgkin's lymphoma	0.067	0.933
D06 Carcinoma in situ of cervix uteri	0.067	0.933
S92 Fracture of foot, except ankle	0.067	0.933
N42.3 Dysplasia of prostate	0.067	0.933
N42.2 Atrophy of prostate	0.067	0.933
N42.1 Congestion and haemorrhage of prostate	0.067	0.933
N42.0 Calculus of prostate	0.067	0.933
M85 Other disorders of bone density and structure	0.067	0.933
M84 Disorders of continuity of bone	0.067	0.933
M83 Adult osteomalacia	0.067	0.933
M82 Osteoporosis in diseases classified elsewhere	0.067	0.933
M80 Osteoporosis with pathological fracture	0.067	0.933
M77.9 Enthesopathy, unspecified	0.067	0.933
M77.8 Other enthesopathies, not elsewhere classified	0.067	0.933
M77.5 Other enthesopathy of foot	0.067	0.933
M77.4 Metatarsalgia	0.067	0.933
M77.3 Calcaneal spur	0.067	0.933
M77.2 Periarthritis of wrist	0.067	0.933
M77.0 Medial epicondylitis	0.067	0.933
P90-P96 Other disorders originating in the perinatal period	0.067	0.933
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn	0.067	0.933
P75-P78 Digestive system disorders of fetus and newborn	0.067	0.933
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn	0.067	0.933
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn	0.067	0.933
P35-P39 Infections specific to the perinatal period	0.067	0.933
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period	0.067	0.933
P10-P15 Birth trauma	0.067	0.933
P05-P08 Disorders related to length of gestation and fetal growth	0.067	0.933
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery	0.067	0.933
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.067	0.933
Q80-Q89 Other congenital malformations	0.067	0.933
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.067	0.933
Q60-Q64 Congenital malformations of the urinary system	0.067	0.933
Q50-Q56 Congenital malformations of genital organs	0.067	0.933
Q38-Q45 Other congenital malformations of the digestive system	0.067	0.933
Q35-Q37 Cleft lip and cleft palate	0.067	0.933
Q30-Q34 Congenital malformations of the respiratory system	0.067	0.933
Q20-Q28 Congenital malformations of the circulatory system	0.067	0.933
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.067	0.933
Q00-Q07 Congenital malformations of the nervous system	0.067	0.933
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.067	0.933
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.067	0.933
Chapter X Diseases of the respiratory system	0.067	0.933
D53 Other nutritional anaemias	0.067	0.933
D52 Folate deficiency anaemia	0.067	0.933
D51 Vitamin B12 deficiency anaemia	0.067	0.933
L30.9 Dermatitis, unspecified	0.067	0.933
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.067	0.933
M20.6 Acquired deformity of toe(s), unspecified	0.067	0.933
M20.3 Other deformity of hallux (acquired)	0.067	0.933
M20.0 Deformity of finger(s)	0.067	0.933

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations