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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7298767
log Bayes Factor = 17.6072
Chromosome 12   position 22,475,701  (GRCh37) Explore rs7298767 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Z90 Acquired absence of organs, not elsewhere classified
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.999 0.001 0.000
Z92 Personal history of medical treatment
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.996 0.004 0.000
I30-I52 Other forms of heart disease
0.995 0.005 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.993 0.007 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.992 0.008 0.000
S80-S89 Injuries to the knee and lower leg
0.991 0.009 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.989 0.011 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.988 0.012 0.000
Chapter VIII Diseases of the ear and mastoid process
0.985 0.015 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.983 0.017 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.982 0.018 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.981 0.019 0.000
S82 Fracture of lower leg, including ankle
0.980 0.020 0.000
C78.7 Secondary malignant neoplasm of liver
0.968 0.032 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.964 0.036 0.000
S82.8 Fractures of other parts of lower leg
0.963 0.037 0.000
Z92.3 Personal history of irradiation
0.963 0.037 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.959 0.041 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.959 0.041 0.000
S00-S09 Injuries to the head
0.958 0.042 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.955 0.045 0.000
Chapter XI Diseases of the digestive system
0.953 0.047 0.000
S82.80 Fractures of other parts of lower leg (closed)
0.952 0.048 0.000
D00-D09 In situ neoplasms
0.950 0.050 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.947 0.053 0.000
C15-C26 Malignant neoplasms of digestive organs
0.946 0.054 0.000
Z51 Other medical care
0.940 0.060 0.000
H65-H75 Diseases of middle ear and mastoid
0.939 0.061 0.000
I49 Other cardiac arrhythmias
0.936 0.064 0.000
S60-S69 Injuries to the wrist and hand
0.936 0.064 0.000
Z90.7 Acquired absence of genital organ(s)
0.935 0.065 0.000
Z98 Other postsurgical states
0.934 0.066 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.931 0.069 0.000
I51 Complications and ill-defined descriptions of heart disease
0.929 0.071 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.914 0.086 0.000
Z09.8 Follow-up examination after other treatment for other conditions
0.914 0.086 0.000
Z98.0 Intestinal bypass and anastomosis status
0.913 0.087 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.912 0.088 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.906 0.094 0.000
C78.0 Secondary malignant neoplasm of lung
0.906 0.094 0.000
H72 Perforation of tympanic membrane
0.904 0.096 0.000
C77.1 Intrathoracic lymph nodes
0.903 0.097 0.000
Z46 Fitting and adjustment of other devices
0.902 0.098 0.000
K65-K67 Diseases of peritoneum
0.900 0.100 0.000
Z90.8 Acquired absence of other organs
0.897 0.103 0.000
C77.9 Lymph node, unspecified
0.897 0.103 0.000
I47 Paroxysmal tachycardia
0.892 0.108 0.000
Z51.0 Radiotherapy session
0.891 0.109 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.888 0.112 0.000
C77.2 Intra-abdominal lymph nodes
0.888 0.112 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.886 0.114 0.000
I77 Other disorders of arteries and arterioles
0.885 0.115 0.000
Z97 Presence of other devices
0.885 0.115 0.000
Z01.8 Other specified special examinations
0.881 0.119 0.000
Chapter V Mental and behavioural disorders
0.877 0.123 0.000
S70-S79 Injuries to the hip and thigh
0.872 0.128 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.871 0.129 0.000
I73 Other peripheral vascular diseases
0.871 0.129 0.000
K55-K64 Other diseases of intestines
0.860 0.140 0.000
Z50 Care involving use of rehabilitation procedures
0.858 0.142 0.000
I74 Arterial embolism and thrombosis
0.857 0.143 0.000
K66 Other disorders of peritoneum
0.854 0.146 0.000
I31 Other diseases of pericardium
0.853 0.147 0.000
S09 Other and unspecified injuries of head
0.853 0.147 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.851 0.149 0.000
D45 Polycythaemia vera
0.850 0.150 0.000
D60-D64 Aplastic and other anaemias
0.847 0.153 0.000
I49.3 Ventricular premature depolarisation
0.846 0.154 0.000
H80-H83 Diseases of inner ear
0.842 0.158 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.841 0.159 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.838 0.162 0.000
D04 Carcinoma in situ of skin
0.838 0.162 0.000
D03 Melanoma in situ
0.837 0.163 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.835 0.165 0.000
Z45 Adjustment and management of implanted device
0.834 0.166 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.833 0.167 0.000
I51.7 Cardiomegaly
0.833 0.167 0.000
C77.5 Intrapelvic lymph nodes
0.829 0.171 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.828 0.172 0.000
Z99.1 Dependence on respirator
0.826 0.174 0.000
Z93 Artificial opening status
0.825 0.175 0.000
I71 Aortic aneurysm and dissection
0.824 0.176 0.000
Z13 Special screening examination for other diseases and disorders
0.823 0.177 0.000
Z86 Personal history of certain other diseases
0.823 0.177 0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions
0.821 0.179 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.821 0.179 0.000
K66.0 Peritoneal adhesions
0.821 0.179 0.000
Z90.3 Acquired absence of part of stomach
0.820 0.180 0.000
M65-M68 Disorders of synovium and tendon
0.820 0.180 0.000
S40-S49 Injuries to the shoulder and upper arm
0.818 0.182 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.818 0.182 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.818 0.182 0.000
I73.9 Peripheral vascular disease, unspecified
0.816 0.184 0.000
K70-K77 Diseases of liver
0.816 0.184 0.000
S62 Fracture at wrist and hand level
0.815 0.185 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.813 0.187 0.000
S01 Open wound of head
0.813 0.187 0.000
K57 Diverticular disease of intestine
0.808 0.192 0.000
H90-H95 Other disorders of ear
0.808 0.192 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.807 0.193 0.000
Z01.6 Radiological examination, not elsewhere classified
0.806 0.194 0.000
I45 Other conduction disorders
0.806 0.194 0.000
I44 Atrioventricular and left bundle-branch block
0.805 0.195 0.000
I46 Cardiac arrest
0.805 0.195 0.000
S82.6 Fracture of lateral malleolus
0.804 0.196 0.000
Z01.5 Diagnostic skin and sensitisation tests
0.803 0.197 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.803 0.197 0.000
K50-K52 Noninfective enteritis and colitis
0.803 0.197 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.801 0.199 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.801 0.199 0.000
C79 Secondary malignant neoplasm of other sites
0.799 0.201 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.798 0.202 0.000
S82.3 Fracture of lower end of tibia
0.796 0.204 0.000
S80 Superficial injury of lower leg
0.793 0.207 0.000
Z01.4 Gynaecological examination (general)(routine)
0.791 0.209 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.789 0.211 0.000
T90 Sequelae of injuries of head
0.789 0.211 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.789 0.211 0.000
D70 Agranulocytosis
0.788 0.212 0.000
H60-H62 Diseases of external ear
0.788 0.212 0.000
Chapter XX External causes of morbidity and mortality
0.787 0.213 0.000
I51.8 Other ill-defined heart diseases
0.786 0.214 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.786 0.214 0.000
C15 Malignant neoplasm of oesophagus
0.786 0.214 0.000
S06 Intracranial injury
0.785 0.215 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.783 0.217 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.782 0.218 0.000
Z92.0 Personal history of contraception
0.781 0.219 0.000
I70 Atherosclerosis
0.780 0.220 0.000
I47.2 Ventricular tachycardia
0.780 0.220 0.000
S09.9 Unspecified injury of head
0.779 0.221 0.000
Z48 Other surgical follow-up care
0.778 0.222 0.000
I74.5 Embolism and thrombosis of iliac artery
0.777 0.223 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.775 0.225 0.000
Z97.5 Presence of (intra-uterine) contraceptive device
0.775 0.225 0.000
D06 Carcinoma in situ of cervix uteri
0.773 0.227 0.000
I35 Nonrheumatic aortic valve disorders
0.773 0.227 0.000
Z51.3 Blood transfusion without reported diagnosis
0.773 0.227 0.000
I77.1 Stricture of artery
0.773 0.227 0.000
I51.4 Myocarditis, unspecified
0.772 0.228 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.771 0.229 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.769 0.231 0.000
Z42 Follow-up care involving plastic surgery
0.769 0.231 0.000
Z09.0 Follow-up examination after surgery for other conditions
0.768 0.232 0.000
I34 Nonrheumatic mitral valve disorders
0.768 0.232 0.000
I49.9 Cardiac arrhythmia, unspecified
0.767 0.233 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.767 0.233 0.000
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances
0.766 0.234 0.000
K56.5 Intestinal adhesions [bands] with obstruction
0.763 0.237 0.000
C78.2 Secondary malignant neoplasm of pleura
0.763 0.237 0.000
T43.2 Other and unspecified antidepressants
0.762 0.238 0.000
I36 Nonrheumatic tricuspid valve disorders
0.761 0.238 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.761 0.239 0.000
S81 Open wound of lower leg
0.760 0.239 0.000
T93 Sequelae of injuries of lower limb
0.758 0.242 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.757 0.243 0.000
C16 Malignant neoplasm of stomach
0.756 0.244 0.000
K56.7 Ileus, unspecified
0.754 0.246 0.000
I31.9 Disease of pericardium, unspecified
0.753 0.247 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.753 0.247 0.000
S64 Injury of nerves at wrist and hand level
0.753 0.247 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.751 0.249 0.000
S72 Fracture of femur
0.751 0.249 0.000
Z51.2 Other chemotherapy
0.750 0.250 0.000
Chapter I Certain infectious and parasitic diseases
0.748 0.252 0.000
C18 Malignant neoplasm of colon
0.747 0.253 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.746 0.254 0.000
Z46.6 Fitting and adjustment of urinary device
0.745 0.255 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.745 0.255 0.000
I05-I09 Chronic rheumatic heart diseases
0.744 0.256 0.000
M80-M85 Disorders of bone density and structure
0.744 0.256 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.743 0.256 0.000
C77.3 Axillary and upper limb lymph nodes
0.743 0.257 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.742 0.258 0.000
T86 Failure and rejection of transplanted organs and tissues
0.742 0.258 0.000
I77.6 Arteritis, unspecified
0.739 0.261 0.000
S05 Injury of eye and orbit
0.739 0.261 0.000
Z92.8 Personal history of other medical treatment
0.739 0.261 0.000
D03.5 Melanoma in situ of trunk
0.737 0.263 0.000
C77.8 Lymph nodes of multiple regions
0.737 0.263 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.736 0.264 0.000
K56.2 Volvulus
0.735 0.265 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.735 0.265 0.000
T92 Sequelae of injuries of upper limb
0.733 0.267 0.000
H73 Other disorders of tympanic membrane
0.731 0.269 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.731 0.269 0.000
Z49 Care involving dialysis
0.731 0.269 0.000
Z51.1 Chemotherapy session for neoplasm
0.730 0.270 0.000
M86-M90 Other osteopathies
0.730 0.270 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.730 0.270 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.730 0.270 0.000
H81 Disorders of vestibular function
0.729 0.271 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.729 0.271 0.000
L60-L75 Disorders of skin appendages
0.728 0.271 0.000
S61 Open wound of wrist and hand
0.728 0.272 0.000
I47.1 Supraventricular tachycardia
0.726 0.274 0.000
I49.4 Other and unspecified premature depolarisation
0.726 0.274 0.000
I49.0 Ventricular fibrillation and flutter
0.725 0.275 0.000
Z50.5 Speech therapy
0.724 0.276 0.000
Z35 Supervision of high-risk pregnancy
0.723 0.277 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.723 0.277 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.722 0.278 0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess
0.722 0.278 0.000
S90-S99 Injuries to the ankle and foot
0.721 0.279 0.000
H71 Cholesteatoma of middle ear
0.720 0.279 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.720 0.280 0.000
Chapter XXII Codes for special purposes
0.720 0.280 0.000
O00-O08 Pregnancy with abortive outcome
0.719 0.281 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.718 0.282 0.000
Z89 Acquired absence of limb
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Z90.0 Acquired absence of part of head and neck
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
Z92.9 Personal history of medical treatment, unspecified
0.716 0.284 0.000
Z92.5 Personal history of rehabilitation measures
0.716 0.284 0.000
Z93.2 Ileostomy status
0.716 0.284 0.000
F41 Other anxiety disorders
0.715 0.284 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.714 0.286 0.000
I00-I02 Acute rheumatic fever
0.714 0.286 0.000
C77.0 Lymph nodes of head, face and neck
0.714 0.286 0.000
S67 Crushing injury of wrist and hand
0.714 0.286 0.000
I52 Other heart disorders in diseases classified elsewhere
0.713 0.287 0.000
I48 Atrial fibrillation and flutter
0.713 0.287 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.713 0.287 0.000
I41 Myocarditis in diseases classified elsewhere
0.713 0.287 0.000
I40 Acute myocarditis
0.713 0.287 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.713 0.287 0.000
I37 Pulmonary valve disorders
0.713 0.287 0.000
I32 Pericarditis in diseases classified elsewhere
0.713 0.287 0.000
I30 Acute pericarditis
0.713 0.287 0.000
Z46.8 Fitting and adjustment of other specified devices
0.713 0.287 0.000
M65 Synovitis and tenosynovitis
0.712 0.288 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.712 0.288 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.712 0.288 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.712 0.288 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.712 0.288 0.000
Z45.8 Adjustment and management of other implanted devices
0.711 0.289 0.000
S89 Other and unspecified injuries of lower leg
0.710 0.290 0.000
S88 Traumatic amputation of lower leg
0.710 0.290 0.000
S87 Crushing injury of lower leg
0.710 0.290 0.000
S86 Injury of muscle and tendon at lower leg level
0.710 0.290 0.000
S85 Injury of blood vessels at lower leg level
0.710 0.290 0.000
S84 Injury of nerves at lower leg level
0.710 0.290 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.710 0.290 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.709 0.290 0.000
Z10 Routine general health check-up of defined subpopulation
0.709 0.291 0.000
Z54 Convalescence
0.708 0.291 0.000
Z52 Donors of organs and tissues
0.708 0.291 0.000
Z44 Fitting and adjustment of external prosthetic device
0.708 0.291 0.000
H72.8 Other perforations of tympanic membrane
0.706 0.294 0.000
Z43 Attention to artificial openings
0.705 0.294 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.705 0.295 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.705 0.295 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.705 0.295 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.705 0.295 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.705 0.295 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.705 0.295 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.705 0.295 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.705 0.295 0.000
T36 Poisoning by systemic antibiotics
0.705 0.295 0.000
S82.2 Fracture of shaft of tibia
0.704 0.296 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.703 0.297 0.000
I72 Other aneurysm
0.703 0.297 0.000
I38 Endocarditis, valve unspecified
0.703 0.297 0.000
I33 Acute and subacute endocarditis
0.703 0.297 0.000
S82.9 Fracture of lower leg, part unspecified
0.702 0.298 0.000
S82.7 Multiple fractures of lower leg
0.702 0.298 0.000
S82.5 Fracture of medial malleolus
0.702 0.298 0.000
S82.0 Fracture of patella
0.702 0.298 0.000
M70-M79 Other soft tissue disorders
0.699 0.301 0.000
C80 Malignant neoplasm without specification of site
0.699 0.301 0.000
D04.6 Skin of upper limb, including shoulder
0.698 0.302 0.000
S20-S29 Injuries to the thorax
0.697 0.302 0.000
K13 Other diseases of lip and oral mucosa
0.697 0.303 0.000
K51 Ulcerative colitis
0.696 0.304 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.695 0.305 0.000
K76 Other diseases of liver
0.695 0.305 0.000
K65 Peritonitis
0.695 0.305 0.000
D05 Carcinoma in situ of breast
0.694 0.306 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.692 0.308 0.000
Z01.9 Special examination, unspecified
0.691 0.309 0.000
Z01.7 Laboratory examination
0.691 0.309 0.000
Z01.3 Examination of blood pressure
0.691 0.309 0.000
Z01.2 Dental examination
0.691 0.309 0.000
Z01.1 Examination of ears and hearing
0.691 0.309 0.000
Z01.0 Examination of eyes and vision
0.691 0.309 0.000
S82.86 Maisonneuve's fracture
0.691 0.309 0.000
S82.81 Fractures of other parts of lower leg (open)
0.691 0.309 0.000
M60-M63 Disorders of muscles
0.690 0.310 0.000
O36 Maternal care for other known or suspected foetal problems
0.690 0.310 0.000
T43.9 Psychotropic drug, unspecified
0.688 0.312 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.688 0.312 0.000
T43.6 Psychostimulants with abuse potential
0.688 0.312 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.688 0.312 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.688 0.312 0.000
Z09.7 Follow-up examination after combined treatment for other conditions
0.688 0.312 0.000
Z09.4 Follow-up examination after treatment of fracture
0.688 0.312 0.000
Z09.3 Follow-up examination after psychotherapy
0.688 0.312 0.000
Z09.1 Follow-up examination after radiotherapy for other conditions
0.688 0.312 0.000
S08 Traumatic amputation of part of head
0.687 0.313 0.000
S07 Crushing injury of head
0.687 0.313 0.000
S04 Injury of cranial nerves
0.687 0.313 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.687 0.313 0.000
S70 Superficial injury of hip and thigh
0.686 0.314 0.000
A00-A09 Intestinal infectious diseases
0.685 0.315 0.000
C77.4 Inguinal and lower limb lymph nodes
0.685 0.315 0.000
D55-D59 Haemolytic anaemias
0.685 0.315 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.685 0.315 0.000
Z50.8 Care involving use of rehabilitation procedures
0.685 0.315 0.000
D66 Hereditary factor VIII deficiency
0.685 0.315 0.000
F99-F99 Unspecified mental disorder
0.684 0.316 0.000
K57.1 Diverticular disease of small intestine without perforation or abscess
0.684 0.316 0.000
D80-D89 Certain disorders involving the immune mechanism
0.684 0.316 0.000
Z90.5 Acquired absence of kidney
0.684 0.316 0.000
Z97.4 Presence of external hearing-aid
0.683 0.316 0.000
Chapter VI Diseases of the nervous system
0.683 0.317 0.000
S82.4 Fracture of fibula alone
0.682 0.318 0.000
S42 Fracture of shoulder and upper arm
0.682 0.318 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.682 0.318 0.000
S00 Superficial injury of head
0.682 0.318 0.000
S62.8 Fracture of other and unspecified parts of wrist and hand
0.681 0.319 0.000
D09 Carcinoma in situ of other and unspecified sites
0.681 0.319 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.681 0.319 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.681 0.319 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.681 0.319 0.000
K50 Crohn's disease [regional enteritis]
0.681 0.319 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.680 0.320 0.000
T42.1 Iminostilbenes
0.680 0.320 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.680 0.320 0.000
I49.5 Sick sinus syndrome
0.680 0.320 0.000
S01.8 Open wound of other parts of head
0.679 0.321 0.000
S82.60 Fracture of lateral malleolus (closed)
0.679 0.321 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.679 0.321 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.679 0.321 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.679 0.321 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.679 0.321 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.679 0.321 0.000
S01.5 Open wound of lip and oral cavity
0.678 0.322 0.000
M40-M43 Deforming dorsopathies
0.678 0.322 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.678 0.322 0.000
C21 Malignant neoplasm of anus and anal canal
0.678 0.322 0.000
C17 Malignant neoplasm of small intestine
0.678 0.322 0.000
C23 Malignant neoplasm of gallbladder
0.678 0.322 0.000
Z50.2 Alcohol rehabilitation
0.678 0.322 0.000
M67 Other disorders of synovium and tendon
0.677 0.323 0.000
C20 Malignant neoplasm of rectum
0.677 0.323 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.676 0.323 0.000
K35-K38 Diseases of appendix
0.676 0.324 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.675 0.324 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.675 0.325 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.675 0.325 0.000
S02 Fracture of skull and facial bones
0.675 0.325 0.000
F41.9 Anxiety disorder, unspecified
0.674 0.326 0.000
Z51.9 Medical care, unspecified
0.674 0.326 0.000
Z51.6 Desensitisation to allergens
0.674 0.326 0.000
D61 Other aplastic anaemias
0.674 0.326 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.673 0.327 0.000
H74 Other disorders of middle ear and mastoid
0.673 0.327 0.000
H70 Mastoiditis and related conditions
0.673 0.327 0.000
H69 Other disorders of Eustachian tube
0.673 0.327 0.000
H68 Eustachian salpingitis and obstruction
0.673 0.327 0.000
H67 Otitis media in diseases classified elsewhere
0.673 0.327 0.000
M00-M03 Infectious arthropathies
0.673 0.327 0.000
Z41 Procedures for purposes other than remedying health state
0.673 0.327 0.000
T66-T78 Other and unspecified effects of external causes
0.673 0.327 0.000
H90 Conductive and sensorineural hearing loss
0.672 0.328 0.000
S82.1 Fracture of upper end of tibia
0.672 0.328 0.000
I49.2 Junctional premature depolarisation
0.671 0.329 0.000
I49.1 Atrial premature depolarisation
0.671 0.329 0.000
S69 Other and unspecified injuries of wrist and hand
0.671 0.329 0.000
S65 Injury of blood vessels at wrist and hand level
0.671 0.329 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.671 0.329 0.000
S60 Superficial injury of wrist and hand
0.671 0.329 0.000
M45-M49 Spondylopathies
0.671 0.329 0.000
Z98.2 Presence of cerebrospinal fluid drainage device
0.670 0.330 0.000
M20-M25 Other joint disorders
0.670 0.330 0.000
Z86.4 Personal history of psychoactive substance abuse
0.668 0.332 0.000
D68 Other coagulation defects
0.668 0.332 0.000
C15.9 Oesophagus, unspecified
0.668 0.332 0.000
T98 Sequelae of other and unspecified effects of external causes
0.667 0.333 0.000
T95 Sequelae of burns, corrosions and frostbite
0.667 0.333 0.000
T91 Sequelae of injuries of neck and trunk
0.667 0.333 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.667 0.333 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.667 0.333 0.000
Z60 Problems related to social environment
0.667 0.333 0.000
I44.0 Atrioventricular block, first degree
0.666 0.334 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.666 0.334 0.000
I51.6 Cardiovascular disease, unspecified
0.666 0.334 0.000
I51.5 Myocardial degeneration
0.666 0.334 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.666 0.334 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.666 0.334 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.666 0.334 0.000
I51.0 Cardiac septal defect, acquired
0.666 0.334 0.000
Z12 Special screening examination for neoplasms
0.666 0.334 0.000
D40.0 Prostate
0.666 0.334 0.000
O46.9 Antepartum haemorrhage, unspecified
0.666 0.334 0.000
Z86.0 Personal history of other neoplasms
0.666 0.334 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.665 0.335 0.000
D46 Myelodysplastic syndromes
0.665 0.335 0.000
S82.30 Fracture of lower end of tibia (closed)
0.665 0.335 0.000
Z13.1 Special screening examination for diabetes mellitus
0.663 0.337 0.000
Z29 Need for other prophylactic measures
0.662 0.338 0.000
Z48.9 Surgical follow-up care, unspecified
0.661 0.339 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.661 0.339 0.000
D04.7 Skin of lower limb, including hip
0.661 0.339 0.000
D63.0 Anaemia in neoplastic disease
0.660 0.340 0.000
Z34 Supervision of normal pregnancy
0.660 0.340 0.000
F30-F39 Mood [affective] disorders
0.660 0.340 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.659 0.341 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.658 0.341 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.658 0.342 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.658 0.342 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.657 0.343 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.657 0.343 0.000
L40-L45 Papulosquamous disorders
0.657 0.343 0.000
I95 Hypotension
0.656 0.344 0.000
D69 Purpura and other haemorrhagic conditions
0.656 0.344 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.656 0.344 0.000
D04.5 Skin of trunk
0.655 0.345 0.000
K90-K93 Other diseases of the digestive system
0.654 0.346 0.000
K76.8 Other specified diseases of liver
0.654 0.346 0.000
M91-M94 Chondropathies
0.654 0.346 0.000
Z97.8 Presence of other specified devices
0.652 0.347 0.000
S80.9 Superficial injury of lower leg, unspecified
0.651 0.349 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.651 0.349 0.000
T82.1 Mechanical complication of cardiac electronic device
0.651 0.349 0.000
I45.5 Other specified heart block
0.649 0.351 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.648 0.352 0.000
H72.2 Other marginal perforations of tympanic membrane
0.648 0.352 0.000
H72.1 Attic perforation of tympanic membrane
0.648 0.352 0.000
H72.0 Central perforation of tympanic membrane
0.648 0.352 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.647 0.353 0.000
D06.9 Cervix, unspecified
0.647 0.353 0.000
H61 Other disorders of external ear
0.647 0.353 0.000
Z46.9 Fitting and adjustment of other unspecified device
0.647 0.353 0.000
Z46.7 Fitting and adjustment of orthopaedic device
0.647 0.353 0.000
Z46.4 Fitting and adjustment of orthodontic device
0.647 0.353 0.000
Z46.3 Fitting and adjustment of dental prosthetic device
0.647 0.353 0.000
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses
0.647 0.353 0.000
Z46.1 Fitting and adjustment of hearing aid
0.647 0.353 0.000
Z46.0 Fitting and adjustment of spectacles and contact lenses
0.647 0.353 0.000
D03.6 Melanoma in situ of upper limb, including shoulder
0.647 0.353 0.000
S06.5 Traumatic subdural haemorrhage
0.646 0.354 0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere
0.646 0.354 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.645 0.355 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.645 0.355 0.000
T90.9 Sequelae of unspecified injury of head
0.645 0.355 0.000
Z04 Examination and observation for other reasons
0.645 0.355 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.644 0.356 0.000
C79.2 Secondary malignant neoplasm of skin
0.642 0.358 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.639 0.361 0.000
I47.0 Reentry ventricular arrhythmia
0.639 0.361 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.639 0.361 0.000
K74 Fibrosis and cirrhosis of liver
0.638 0.362 0.000
Z42.0 Follow-up care involving plastic surgery of head and neck
0.637 0.363 0.000
I46.9 Cardiac arrest, unspecified
0.637 0.363 0.000
T87 Complications peculiar to reattachment and amputation
0.637 0.363 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.637 0.363 0.000
C16.9 Stomach, unspecified
0.637 0.363 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.636 0.363 0.000
Z99.9 Dependence on unspecified enabling machine and device
0.635 0.365 0.000
Z99.4 Dependence on artificial heart
0.635 0.365 0.000
Z99.0 Dependence on aspirator
0.635 0.365 0.000
I77.8 Other specified disorders of arteries and arterioles
0.635 0.365 0.000
I77.5 Necrosis of artery
0.635 0.365 0.000
I77.4 Coeliac artery compression syndrome
0.635 0.365 0.000
I77.3 Arterial fibromuscular dysplasia
0.635 0.365 0.000
I77.2 Rupture of artery
0.635 0.365 0.000
I77.0 Arteriovenous fistula, acquired
0.635 0.365 0.000
Z93.1 Gastrostomy status
0.635 0.365 0.000
Z97.3 Presence of spectacles and contact lenses
0.635 0.365 0.000
Z97.2 Presence of dental prosthetic device (complete)(partial)
0.635 0.365 0.000
Z97.1 Presence of artificial limb (complete)(partial)
0.635 0.365 0.000
Z97.0 Presence of artificial eye
0.635 0.365 0.000
I44.1 Atrioventricular block, second degree
0.634 0.365 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.634 0.365 0.000
K57.2 Diverticular disease of large intestine with perforation and abscess
0.634 0.366 0.000
Z50.1 Other physical therapy
0.633 0.367 0.000
C73 Malignant neoplasm of thyroid gland
0.633 0.367 0.000
Z93.6 Other artificial openings of urinary tract status
0.633 0.367 0.000
Z99.2 Dependence on renal dialysis
0.631 0.368 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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