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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72999187
log Bayes Factor = 16.0305
Chromosome 6   position 149,148,901  (GRCh37) Explore rs72999187 on Ensembl!
Variant rs72999187 is part of Cluster X0290

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
0.998 0.002 0.000
E11 Non-insulin-dependent diabetes mellitus
0.998 0.002 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.998 0.002 0.000
Chapter XXI Factors influencing health status and contact with health services
0.996 0.004 0.000
I50 Heart failure
0.996 0.004 0.000
O60-O75 Complications of labour and delivery
0.995 0.005 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.994 0.006 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.993 0.007 0.000
E11.9 Without complications
0.992 0.008 0.000
I25 Chronic ischaemic heart disease
0.991 0.009 0.000
I50.0 Congestive heart failure
0.982 0.018 0.000
E10 Insulin-dependent diabetes mellitus
0.981 0.019 0.000
Z80 Family history of malignant neoplasm
0.979 0.021 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.978 0.022 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.977 0.023 0.000
E70-E90 Metabolic disorders
0.977 0.023 0.000
Chapter VII Diseases of the eye and adnexa
0.969 0.031 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.964 0.036 0.000
E10.9 Without complications
0.959 0.041 0.000
I25.2 Old myocardial infarction
0.957 0.043 0.000
I51 Complications and ill-defined descriptions of heart disease
0.956 0.044 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.955 0.045 0.000
Z80.3 Family history of malignant neoplasm of breast
0.949 0.051 0.000
I50.9 Heart failure, unspecified
0.947 0.053 0.000
Z95.1 Presence of aortocoronary bypass graft
0.945 0.055 0.000
I34 Nonrheumatic mitral valve disorders
0.938 0.062 0.000
Chapter I Certain infectious and parasitic diseases
0.934 0.066 0.000
H02 Other disorders of eyelid
0.929 0.071 0.000
H00 Hordeolum and chalazion
0.927 0.073 0.000
I51.7 Cardiomegaly
0.922 0.078 0.000
Chapter V Mental and behavioural disorders
0.921 0.079 0.000
I21 Acute myocardial infarction
0.918 0.082 0.000
O72 Postpartum haemorrhage
0.909 0.091 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.906 0.094 0.000
A30-A49 Other bacterial diseases
0.904 0.096 0.000
H00.1 Chalazion
0.901 0.099 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.901 0.099 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.896 0.104 0.000
E65-E68 Obesity and other hyperalimentation
0.895 0.105 0.000
O70 Perineal laceration during delivery
0.895 0.105 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.893 0.107 0.000
L03 Cellulitis
0.891 0.109 0.000
I34.0 Mitral (valve) insufficiency
0.886 0.114 0.000
I05-I09 Chronic rheumatic heart diseases
0.883 0.117 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.882 0.118 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.876 0.124 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.876 0.124 0.000
Chapter VI Diseases of the nervous system
0.874 0.126 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.874 0.126 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.868 0.132 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.866 0.134 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.865 0.135 0.000
A41 Other septicaemia
0.864 0.136 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.863 0.137 0.000
L60-L75 Disorders of skin appendages
0.860 0.140 0.000
Z83 Family history of other specific disorders
0.859 0.141 0.000
E13 Other specified diabetes mellitus
0.851 0.149 0.000
I46 Cardiac arrest
0.850 0.150 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.848 0.152 0.000
I20 Angina pectoris
0.848 0.152 0.000
E11.5 With peripheral circulatory complications
0.848 0.152 0.000
I21.4 Acute subendocardial myocardial infarction
0.847 0.153 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.844 0.156 0.000
I21.9 Acute myocardial infarction, unspecified
0.837 0.163 0.000
Z95.0 Presence of cardiac pacemaker
0.834 0.166 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.834 0.166 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.826 0.174 0.000
Chapter XXII Codes for special purposes
0.826 0.174 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.822 0.178 0.000
E11.4 With neurological complications
0.822 0.178 0.000
O66 Other obstructed labour
0.820 0.180 0.000
I51.9 Heart disease, unspecified
0.819 0.181 0.000
Z89 Acquired absence of limb
0.819 0.181 0.000
H02.8 Other specified disorders of eyelid
0.818 0.182 0.000
I27 Other pulmonary heart diseases
0.818 0.182 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.817 0.183 0.000
S80-S89 Injuries to the knee and lower leg
0.816 0.184 0.000
S20-S29 Injuries to the thorax
0.816 0.184 0.000
I35 Nonrheumatic aortic valve disorders
0.811 0.189 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.811 0.189 0.000
Chapter XIV Diseases of the genitourinary system
0.811 0.189 0.000
I33 Acute and subacute endocarditis
0.809 0.191 0.000
A41.9 Septicaemia, unspecified
0.809 0.191 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.807 0.193 0.000
E78.0 Pure hypercholesterolaemia
0.807 0.193 0.000
Z95.4 Presence of other heart-valve replacement
0.806 0.194 0.000
I25.3 Aneurysm of heart
0.805 0.195 0.000
H02.0 Entropion and trichiasis of eyelid
0.805 0.195 0.000
Z93 Artificial opening status
0.804 0.196 0.000
A00-A09 Intestinal infectious diseases
0.804 0.196 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.803 0.197 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.803 0.197 0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs
0.802 0.198 0.000
Chapter II Neoplasms
0.801 0.199 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.801 0.199 0.000
O63 Long labour
0.800 0.200 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.799 0.201 0.000
I25.5 Ischaemic cardiomyopathy
0.799 0.201 0.000
I20.9 Angina pectoris, unspecified
0.795 0.205 0.000
N17-N19 Renal failure
0.795 0.205 0.000
H30-H36 Disorders of choroid and retina
0.794 0.206 0.000
Chapter VIII Diseases of the ear and mastoid process
0.793 0.207 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.793 0.207 0.000
E83 Disorders of mineral metabolism
0.792 0.208 0.000
E11.6 With other specified complications
0.791 0.209 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.790 0.210 0.000
S32 Fracture of lumbar spine and pelvis
0.790 0.210 0.000
E66 Obesity
0.789 0.211 0.000
I95 Hypotension
0.787 0.213 0.000
S00-S09 Injuries to the head
0.786 0.214 0.000
O00-O08 Pregnancy with abortive outcome
0.786 0.214 0.000
L50-L54 Urticaria and erythema
0.785 0.215 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.785 0.215 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.785 0.215 0.000
O70.1 Second degree perineal laceration during delivery
0.785 0.215 0.000
Z95.3 Presence of xenogenic heart valve
0.784 0.216 0.000
Z37 Outcome of delivery
0.779 0.221 0.000
S90-S99 Injuries to the ankle and foot
0.779 0.221 0.000
H10-H13 Disorders of conjunctiva
0.779 0.221 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.777 0.223 0.000
Z88.5 Personal history of allergy to narcotic agent
0.776 0.224 0.000
E10.3 With ophthalmic complications
0.776 0.224 0.000
H05 Disorders of orbit
0.774 0.226 0.000
H02.9 Disorder of eyelid, unspecified
0.772 0.228 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.771 0.229 0.000
E20-E35 Disorders of other endocrine glands
0.769 0.230 0.000
E86 Volume depletion
0.769 0.231 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.768 0.232 0.000
L03.1 Cellulitis of other parts of limb
0.767 0.233 0.000
Z94 Transplanted organ and tissue status
0.767 0.233 0.000
Z97 Presence of other devices
0.767 0.233 0.000
O72.1 Other immediate postpartum haemorrhage
0.766 0.234 0.000
Z80.8 Family history of malignant neoplasm of other organs or systems
0.766 0.234 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.766 0.234 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.765 0.235 0.000
L20-L30 Dermatitis and eczema
0.764 0.236 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.761 0.239 0.000
Z80.0 Family history of malignant neoplasm of digestive organs
0.760 0.240 0.000
S10-S19 Injuries to the neck
0.758 0.242 0.000
A46 Erysipelas
0.758 0.242 0.000
N18 Chronic renal failure
0.757 0.243 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.756 0.244 0.000
H43-H45 Disorders of vitreous body and globe
0.753 0.247 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.752 0.248 0.000
T90 Sequelae of injuries of head
0.752 0.248 0.000
I71 Aortic aneurysm and dissection
0.751 0.249 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.749 0.251 0.000
E50-E64 Other nutritional deficiencies
0.748 0.252 0.000
E10.1 With ketoacidosis
0.747 0.253 0.000
Z98 Other postsurgical states
0.746 0.254 0.000
H02.1 Ectropion of eyelid
0.745 0.254 0.000
I49 Other cardiac arrhythmias
0.745 0.254 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.744 0.256 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.744 0.256 0.000
E13.9 Without complications
0.744 0.256 0.000
I31 Other diseases of pericardium
0.743 0.257 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.743 0.257 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.743 0.257 0.000
T66-T78 Other and unspecified effects of external causes
0.743 0.257 0.000
L08 Other local infections of skin and subcutaneous tissue
0.742 0.258 0.000
F60-F69 Disorders of adult personality and behaviour
0.741 0.259 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.741 0.259 0.000
O73 Retained placenta and membranes, without haemorrhage
0.738 0.261 0.000
I07 Rheumatic tricuspid valve diseases
0.738 0.262 0.000
Z80.4 Family history of malignant neoplasm of genital organs
0.736 0.264 0.000
L03.2 Cellulitis of face
0.736 0.264 0.000
L03.0 Cellulitis of finger and toe
0.735 0.265 0.000
E78.8 Other disorders of lipoprotein metabolism
0.733 0.267 0.000
L72.0 Epidermal cyst
0.733 0.267 0.000
S01 Open wound of head
0.733 0.267 0.000
S27 Injury of other and unspecified intrathoracic organs
0.733 0.267 0.000
Z83.7 Family history of diseases of the digestive system
0.731 0.269 0.000
Z92 Personal history of medical treatment
0.731 0.269 0.000
Z80.9 Family history of malignant neoplasm, unspecified
0.730 0.270 0.000
O70.0 First degree perineal laceration during delivery
0.730 0.270 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.729 0.271 0.000
E88 Other metabolic disorders
0.729 0.271 0.000
S70-S79 Injuries to the hip and thigh
0.722 0.278 0.000
O62 Abnormalities of forces of labour
0.720 0.280 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.720 0.280 0.000
I24 Other acute ischaemic heart diseases
0.719 0.281 0.000
E40-E46 Malnutrition
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I30 Acute pericarditis
0.717 0.283 0.000
I22 Subsequent myocardial infarction
0.717 0.283 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.716 0.284 0.000
E11.8 With unspecified complications
0.715 0.285 0.000
E11.7 With multiple complications
0.715 0.285 0.000
E11.1 With ketoacidosis
0.715 0.285 0.000
E11.0 With coma
0.715 0.285 0.000
O85-O92 Complications predominantly related to the puerperium
0.715 0.285 0.000
I10-I15 Hypertensive diseases
0.715 0.285 0.000
I27.0 Primary pulmonary hypertension
0.715 0.285 0.000
E65 Localised adiposity
0.715 0.285 0.000
E87.7 Fluid overload
0.714 0.285 0.000
O74 Complications of anaesthesia during labour and delivery
0.714 0.286 0.000
O71 Other obstetric trauma
0.714 0.286 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.714 0.286 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.714 0.286 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.714 0.286 0.000
O61 Failed induction of labour
0.714 0.286 0.000
O60 Preterm delivery
0.714 0.286 0.000
Z84 Family history of other conditions
0.713 0.287 0.000
Z81 Family history of mental and behavioural disorders
0.713 0.287 0.000
T33-T35 Frostbite
0.712 0.288 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.712 0.288 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.712 0.288 0.000
T00-T07 Injuries involving multiple body regions
0.712 0.288 0.000
Z37.0 Single live birth
0.712 0.288 0.000
I34.1 Mitral (valve) prolapse
0.711 0.289 0.000
I25.6 Silent myocardial ischaemia
0.711 0.289 0.000
I25.4 Coronary artery aneurysm
0.711 0.289 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.711 0.289 0.000
E87.5 Hyperkalaemia
0.710 0.290 0.000
E11.3 With ophthalmic complications
0.709 0.291 0.000
N18.9 Chronic renal failure, unspecified
0.709 0.291 0.000
L03.9 Cellulitis, unspecified
0.709 0.291 0.000
E11.2 With renal complications
0.708 0.292 0.000
I08 Multiple valve diseases
0.708 0.292 0.000
I46.0 Cardiac arrest with successful resuscitation
0.707 0.293 0.000
E10.8 With unspecified complications
0.703 0.297 0.000
E10.7 With multiple complications
0.703 0.297 0.000
E10.6 With other specified complications
0.703 0.297 0.000
E10.5 With peripheral circulatory complications
0.703 0.297 0.000
E10.4 With neurological complications
0.703 0.297 0.000
E10.2 With renal complications
0.703 0.297 0.000
E10.0 With coma
0.703 0.297 0.000
L40-L45 Papulosquamous disorders
0.703 0.297 0.000
S81 Open wound of lower leg
0.702 0.298 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.702 0.298 0.000
Z83.5 Family history of eye and ear disorders
0.702 0.298 0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues
0.702 0.298 0.000
Z80.6 Family history of leukaemia
0.702 0.298 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.702 0.298 0.000
L10-L14 Bullous disorders
0.701 0.299 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.701 0.299 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.701 0.299 0.000
E85 Amyloidosis
0.701 0.299 0.000
E84 Cystic fibrosis
0.701 0.299 0.000
E79 Disorders of purine and pyrimidine metabolism
0.701 0.299 0.000
E77 Disorders of glycoprotein metabolism
0.701 0.299 0.000
E76 Disorders of glycosaminoglycan metabolism
0.701 0.299 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.701 0.299 0.000
E74 Other disorders of carbohydrate metabolism
0.701 0.299 0.000
E73 Lactose intolerance
0.701 0.299 0.000
E72 Other disorders of amino-acid metabolism
0.701 0.299 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.701 0.299 0.000
E70 Disorders of aromatic amino-acid metabolism
0.701 0.299 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.701 0.299 0.000
Z35 Supervision of high-risk pregnancy
0.700 0.300 0.000
Z93.3 Colostomy status
0.699 0.301 0.000
D45 Polycythaemia vera
0.699 0.301 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.699 0.301 0.000
H02.3 Blepharochalasis
0.699 0.301 0.000
T92 Sequelae of injuries of upper limb
0.698 0.302 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.697 0.303 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.696 0.304 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.695 0.305 0.000
O66.0 Obstructed labour due to shoulder dystocia
0.695 0.305 0.000
M45-M49 Spondylopathies
0.694 0.306 0.000
G40-G47 Episodic and paroxysmal disorders
0.693 0.307 0.000
I42 Cardiomyopathy
0.693 0.307 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.692 0.308 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.692 0.308 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.691 0.309 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.691 0.309 0.000
O80-O84 Delivery
0.691 0.309 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.689 0.311 0.000
C44 Other malignant neoplasms of skin
0.689 0.311 0.000
S50-S59 Injuries to the elbow and forearm
0.689 0.311 0.000
T79-T79 Certain early complications of trauma
0.688 0.312 0.000
I45 Other conduction disorders
0.687 0.313 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.686 0.314 0.000
I51.6 Cardiovascular disease, unspecified
0.686 0.314 0.000
I51.5 Myocardial degeneration
0.686 0.314 0.000
I51.4 Myocarditis, unspecified
0.686 0.314 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.686 0.314 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.686 0.314 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.686 0.314 0.000
I51.0 Cardiac septal defect, acquired
0.686 0.314 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.685 0.315 0.000
L04 Acute lymphadenitis
0.684 0.315 0.000
L01 Impetigo
0.684 0.315 0.000
L00 Staphylococcal scalded skin syndrome
0.684 0.315 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.684 0.316 0.000
Z39 Postpartum care and examination
0.684 0.316 0.000
M40-M43 Deforming dorsopathies
0.684 0.316 0.000
I27.2 Other secondary pulmonary hypertension
0.683 0.317 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.682 0.318 0.000
N17 Acute renal failure
0.681 0.319 0.000
N81 Female genital prolapse
0.681 0.319 0.000
E83.3 Disorders of phosphorus metabolism
0.681 0.319 0.000
S40-S49 Injuries to the shoulder and upper arm
0.681 0.319 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.680 0.320 0.000
Z88.2 Personal history of allergy to sulphonamides
0.680 0.320 0.000
L05 Pilonidal cyst
0.680 0.320 0.000
A04 Other bacterial intestinal infections
0.679 0.320 0.000
F99-F99 Unspecified mental disorder
0.679 0.321 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.679 0.321 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.678 0.322 0.000
B35-B49 Mycoses
0.678 0.322 0.000
I05 Rheumatic mitral valve diseases
0.677 0.323 0.000
E66.8 Other obesity
0.675 0.325 0.000
T86 Failure and rejection of transplanted organs and tissues
0.675 0.325 0.000
I95.1 Orthostatic hypotension
0.673 0.327 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.673 0.327 0.000
H04 Disorders of lachrymal system
0.673 0.327 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.673 0.327 0.000
I33.0 Acute and subacute infective endocarditis
0.673 0.327 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.672 0.328 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.672 0.328 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.672 0.328 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.672 0.328 0.000
B99-B99 Other infectious diseases
0.669 0.330 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.669 0.330 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.669 0.330 0.000
B65-B83 Helminthiases
0.669 0.330 0.000
B50-B64 Protozoal diseases
0.669 0.330 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.669 0.330 0.000
B15-B19 Viral hepatitis
0.669 0.330 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.669 0.330 0.000
A80-A89 Viral infections of the central nervous system
0.669 0.330 0.000
A75-A79 Rickettsioses
0.669 0.330 0.000
A70-A74 Other diseases caused by chlamydiae
0.669 0.330 0.000
A65-A69 Other spirochaetal diseases
0.669 0.330 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.669 0.330 0.000
A20-A28 Certain zoonotic bacterial diseases
0.669 0.330 0.000
A15-A19 Tuberculosis
0.669 0.330 0.000
E14 Unspecified diabetes mellitus
0.669 0.331 0.000
H33 Retinal detachments and breaks
0.669 0.331 0.000
Z34 Supervision of normal pregnancy
0.668 0.332 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.668 0.332 0.000
I46.9 Cardiac arrest, unspecified
0.668 0.332 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.668 0.332 0.000
O72.0 Third-stage haemorrhage
0.667 0.333 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.666 0.334 0.000
B25-B34 Other viral diseases
0.666 0.334 0.000
H02.7 Other degenerative disorders of eyelid and periocular area
0.666 0.334 0.000
H02.5 Other disorders affecting eyelid function
0.666 0.334 0.000
H02.2 Lagophthalmos
0.666 0.334 0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head
0.665 0.335 0.000
N19 Unspecified renal failure
0.664 0.336 0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified
0.663 0.337 0.000
I95.9 Hypotension, unspecified
0.663 0.337 0.000
G70-G73 Diseases of myoneural junction and muscle
0.662 0.337 0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.662 0.338 0.000
N83.2 Other and unspecified ovarian cysts
0.662 0.338 0.000
Z89.5 Acquired absence of leg at or below knee
0.661 0.339 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.661 0.339 0.000
F80-F89 Disorders of psychological development
0.661 0.339 0.000
F70-F79 Mental retardation
0.661 0.339 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.659 0.340 0.000
O75.2 Pyrexia during labour, not elsewhere classified
0.659 0.341 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.658 0.342 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.658 0.342 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.658 0.342 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.657 0.343 0.000
A49 Bacterial infection of unspecified site
0.657 0.343 0.000
H55-H59 Other disorders of eye and adnexa
0.657 0.343 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.656 0.344 0.000
G90-G99 Other disorders of the nervous system
0.656 0.344 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.656 0.344 0.000
H00.0 Hordeolum and other deep inflammation of eyelid
0.655 0.345 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.654 0.346 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.654 0.346 0.000
H36 Retinal disorders in diseases classified elsewhere
0.653 0.346 0.000
F03 Unspecified dementia
0.653 0.347 0.000
E78.2 Mixed hyperlipidaemia
0.653 0.347 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.652 0.348 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.652 0.348 0.000
S01.8 Open wound of other parts of head
0.652 0.348 0.000
C43 Malignant melanoma of skin
0.652 0.348 0.000
O72.3 Postpartum coagulation defects
0.652 0.348 0.000
H01 Other inflammation of eyelid
0.650 0.350 0.000
N10-N16 Renal tubulo-interstitial diseases
0.650 0.350 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.649 0.351 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.649 0.351 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.649 0.351 0.000
A48 Other bacterial diseases, not elsewhere classified
0.648 0.352 0.000
A44 Bartonellosis
0.648 0.352 0.000
A43 Nocardiosis
0.648 0.352 0.000
A42 Actinomycosis
0.648 0.352 0.000
A40 Streptococcal septicaemia
0.648 0.352 0.000
A39 Meningococcal infection
0.648 0.352 0.000
A37 Whooping cough
0.648 0.352 0.000
A36 Diphtheria
0.648 0.352 0.000
A32 Listeriosis
0.648 0.352 0.000
A31 Infection due to other mycobacteria
0.648 0.352 0.000
A30 Leprosy [Hansen's disease]
0.648 0.352 0.000
A38 Scarlet fever
0.648 0.352 0.000
A35 Other tetanus
0.648 0.352 0.000
A34 Obstetrical tetanus
0.648 0.352 0.000
A33 Tetanus neonatorum
0.648 0.352 0.000
L53 Other erythematous conditions
0.647 0.353 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.647 0.353 0.000
I49.5 Sick sinus syndrome
0.647 0.353 0.000
I50.1 Left ventricular failure
0.646 0.354 0.000
F30-F39 Mood [affective] disorders
0.646 0.354 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.645 0.354 0.000
I35.1 Aortic (valve) insufficiency
0.645 0.355 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.644 0.356 0.000
I27.9 Pulmonary heart disease, unspecified
0.644 0.356 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.643 0.356 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.643 0.357 0.000
N18.3 Chronic kidney disease, stage 3
0.643 0.357 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.642 0.357 0.000
S37 Injury of urinary and pelvic organs
0.642 0.357 0.000
S36 Injury of intra-abdominal organs
0.642 0.357 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.642 0.357 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.642 0.357 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.642 0.357 0.000
S31 Open wound of abdomen, lower back and pelvis
0.642 0.357 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.642 0.358 0.000
D10-D36 Benign neoplasms
0.642 0.358 0.000
E67 Other hyperalimentation
0.641 0.358 0.000
E68 Sequelae of hyperalimentation
0.641 0.358 0.000
O70.9 Perineal laceration during delivery, unspecified
0.641 0.359 0.000
O70.3 Fourth degree perineal laceration during delivery
0.641 0.359 0.000
Z95.2 Presence of prosthetic heart valve
0.641 0.359 0.000
T93 Sequelae of injuries of lower limb
0.640 0.359 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.640 0.360 0.000
E78.6 Lipoprotein deficiency
0.640 0.360 0.000
E78.4 Other hyperlipidaemia
0.640 0.360 0.000
E78.3 Hyperchylomicronaemia
0.640 0.360 0.000
E78.1 Pure hyperglyceridaemia
0.640 0.360 0.000
E66.9 Obesity, unspecified
0.640 0.360 0.000
G81 Hemiplegia
0.640 0.360 0.000
H44 Disorders of globe
0.639 0.361 0.000
I73 Other peripheral vascular diseases
0.639 0.361 0.000
O70.2 Third degree perineal laceration during delivery
0.639 0.361 0.000
L03.8 Cellulitis of other sites
0.639 0.361 0.000
H05.0 Acute inflammation of orbit
0.638 0.362 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.638 0.362 0.000
S32.1 Fracture of sacrum
0.636 0.364 0.000
A04.8 Other specified bacterial intestinal infections
0.634 0.366 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.634 0.366 0.000
Z89.4 Acquired absence of foot and ankle
0.634 0.366 0.000
I07.1 Tricuspid insufficiency
0.634 0.366 0.000
I35.9 Aortic valve disorder, unspecified
0.633 0.367 0.000
I09 Other rheumatic heart diseases
0.633 0.367 0.000
I06 Rheumatic aortic valve diseases
0.633 0.367 0.000
I28 Other diseases of pulmonary vessels
0.632 0.368 0.000
N00-N08 Glomerular diseases
0.629 0.371 0.000
O63.1 Prolonged second stage (of labour)
0.629 0.371 0.000
Chapter XX External causes of morbidity and mortality
0.629 0.371 0.000
S01.9 Open wound of head, part unspecified
0.628 0.372 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.628 0.372 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.628 0.372 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.628 0.372 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.628 0.372 0.000
I99 Other and unspecified disorders of circulatory system
0.628 0.372 0.000
T98 Sequelae of other and unspecified effects of external causes
0.628 0.372 0.000
T95 Sequelae of burns, corrosions and frostbite
0.628 0.372 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.628 0.372 0.000
T91 Sequelae of injuries of neck and trunk
0.628 0.372 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.628 0.372 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.628 0.372 0.000
C44.5 Skin of trunk
0.627 0.372 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.627 0.373 0.000
T81 Complications of procedures, not elsewhere classified
0.627 0.373 0.000
Z97.4 Presence of external hearing-aid
0.627 0.373 0.000
H02.6 Xanthelasma of eyelid
0.626 0.374 0.000
N81.6 Rectocele
0.626 0.374 0.000
H02.4 Ptosis of eyelid
0.625 0.374 0.000
S32.0 Fracture of lumbar vertebra
0.625 0.374 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.625 0.375 0.000
I71.0 Dissection of aorta [any part]
0.624 0.376 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.624 0.376 0.000
S32.4 Fracture of acetabulum
0.624 0.376 0.000
H60-H62 Diseases of external ear
0.624 0.376 0.000
E87.2 Acidosis
0.623 0.377 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.622 0.377 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.622 0.378 0.000
O02 Other abnormal products of conception
0.621 0.379 0.000
S81.9 Open wound of lower leg, part unspecified
0.621 0.379 0.000
Z46 Fitting and adjustment of other devices
0.621 0.379 0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.621 0.379 0.000
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.621 0.379 0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.621 0.379 0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.621 0.379 0.000
H80-H83 Diseases of inner ear
0.620 0.379 0.000
E89.3 Postprocedural hypopituitarism
0.620 0.379 0.000
Z38 Liveborn infants according to place of birth
0.620 0.380 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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