TreeWAS – Variant ID: rs73093398

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter X Diseases of the respiratory system	1.000	0.000
# Top node	1.000	0.000
J40-J47 Chronic lower respiratory diseases	1.000	0.000
J44 Other chronic obstructive pulmonary disease	1.000	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.998	0.002
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.998	0.002
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.994	0.006
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.992	0.008
Chapter V Mental and behavioural disorders	0.983	0.017
Chapter IX Diseases of the circulatory system	0.978	0.022
J95-J99 Other diseases of the respiratory system	0.975	0.025
I70-I79 Diseases of arteries, arterioles and capillaries	0.974	0.026
J80-J84 Other respiratory diseases principally affecting the interstitium	0.972	0.028
I60-I69 Cerebrovascular diseases	0.969	0.031
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.968	0.032
I73 Other peripheral vascular diseases	0.962	0.038
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.961	0.039
M20-M25 Other joint disorders	0.959	0.041
R02 Gangrene, not elsewhere classified	0.959	0.041
I67 Other cerebrovascular diseases	0.956	0.044
J84 Other interstitial pulmonary diseases	0.955	0.045
R01 Cardiac murmurs and other cardiac sounds	0.954	0.046
J98 Other respiratory disorders	0.953	0.047
I73.0 Raynaud's syndrome	0.952	0.048
M24 Other specific joint derangements	0.948	0.052
Chapter VII Diseases of the eye and adnexa	0.945	0.055
Chapter I Certain infectious and parasitic diseases	0.944	0.056
R04 Haemorrhage from respiratory passages	0.938	0.062
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.937	0.063
Chapter XX External causes of morbidity and mortality	0.935	0.065
I71 Aortic aneurysm and dissection	0.933	0.067
J30-J39 Other diseases of upper respiratory tract	0.932	0.068
T36-T50 Poisoning by drugs, medicaments and biological substances	0.929	0.071
R01.1 Cardiac murmur, unspecified	0.923	0.077
Chapter VI Diseases of the nervous system	0.919	0.081
R06 Abnormalities of breathing	0.916	0.084
J98.1 Pulmonary collapse	0.915	0.085
R04.0 Epistaxis	0.913	0.087
M24.1 Other articular cartilage disorders	0.912	0.088
S00-S09 Injuries to the head	0.910	0.090
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.909	0.091
I67.1 Cerebral aneurysm, nonruptured	0.908	0.092
B95-B98 Bacterial, viral and other infectious agents	0.899	0.101
J84.1 Other interstitial pulmonary diseases with fibrosis	0.898	0.102
J40 Bronchitis, not specified as acute or chronic	0.897	0.103
R00 Abnormalities of heart beat	0.896	0.104
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.886	0.114
F40-F48 Neurotic, stress-related and somatoform disorders	0.886	0.114
J44.9 Chronic obstructive pulmonary disease, unspecified	0.885	0.115
F10 Mental and behavioural disorders due to use of alcohol	0.884	0.116
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.884	0.116
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.883	0.117
M24.16 Other articular cartilage disorders (Lower leg)	0.881	0.119
M45-M49 Spondylopathies	0.874	0.126
R00.0 Tachycardia, unspecified	0.871	0.129
J46 Status asthmaticus	0.867	0.133
S09 Other and unspecified injuries of head	0.867	0.133
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.867	0.133
J44.8 Other specified chronic obstructive pulmonary disease	0.860	0.140
J34 Other disorders of nose and nasal sinuses	0.858	0.142
M25 Other joint disorders, not elsewhere classified	0.853	0.147
I69 Sequelae of cerebrovascular disease	0.853	0.147
M47 Spondylosis	0.851	0.149
H43-H45 Disorders of vitreous body and globe	0.847	0.153
J84.8 Other specified interstitial pulmonary diseases	0.845	0.155
R06.0 Dyspnoea	0.844	0.156
M34 Systemic sclerosis	0.842	0.158
Chapter XII Diseases of the skin and subcutaneous tissue	0.841	0.159
M47.9 Spondylosis, unspecified	0.840	0.160
F10.3 Withdrawal state	0.839	0.161
Chapter IV Endocrine, nutritional and metabolic diseases	0.838	0.162
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.838	0.162
I67.8 Other specified cerebrovascular diseases	0.837	0.163
S09.9 Unspecified injury of head	0.837	0.163
J98.8 Other specified respiratory disorders	0.835	0.165
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.834	0.166
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.834	0.166
G90-G99 Other disorders of the nervous system	0.831	0.169
S06 Intracranial injury	0.826	0.174
J98.0 Diseases of bronchus, not elsewhere classified	0.826	0.174
L80-L99 Other disorders of the skin and subcutaneous tissue	0.825	0.175
B25-B34 Other viral diseases	0.825	0.175
J36 Peritonsillar abscess	0.824	0.176
J00-J06 Acute upper respiratory infections	0.823	0.177
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.822	0.178
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.820	0.180
B35-B49 Mycoses	0.818	0.182
I71.3 Abdominal aortic aneurysm, ruptured	0.816	0.184
T40.2 Other opioids	0.816	0.184
M86-M90 Other osteopathies	0.813	0.186
H10-H13 Disorders of conjunctiva	0.812	0.188
J84.9 Interstitial pulmonary disease, unspecified	0.811	0.189
E70-E90 Metabolic disorders	0.810	0.190
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.809	0.191
S30 Superficial injury of abdomen, lower back and pelvis	0.806	0.194
H55-H59 Other disorders of eye and adnexa	0.801	0.199
I64 Stroke, not specified as haemorrhage or infarction	0.798	0.202
J34.8 Other specified disorders of nose and nasal sinuses	0.797	0.203
M65-M68 Disorders of synovium and tendon	0.796	0.204
L82 Seborrhoeic keratosis	0.794	0.206
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.791	0.209
R47-R49 Symptoms and signs involving speech and voice	0.790	0.210
H46-H48 Disorders of optic nerve and visual pathways	0.790	0.210
E87 Other disorders of fluid, electrolyte and acid-base balance	0.790	0.210
I67.9 Cerebrovascular disease, unspecified	0.790	0.210
Chapter XXII Codes for special purposes	0.789	0.211
J20-J22 Other acute lower respiratory infections	0.788	0.212
M24.0 Loose body in joint	0.786	0.214
S10-S19 Injuries to the neck	0.786	0.214
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.784	0.216
M24.8 Other specific joint derangements, not elsewhere classified	0.783	0.217
R06.4 Hyperventilation	0.782	0.218
F30-F39 Mood [affective] disorders	0.780	0.220
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.777	0.223
I62 Other nontraumatic intracranial haemorrhage	0.775	0.225
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.773	0.227
R06.1 Stridor	0.773	0.227
J99 Respiratory disorders in diseases classified elsewhere	0.773	0.227
F43 Reaction to severe stress, and adjustment disorders	0.769	0.231
M47.96 Spondylosis, unspecified (Lumbar region)	0.769	0.231
J32 Chronic sinusitis	0.768	0.232
M22 Disorders of patella	0.768	0.232
S40-S49 Injuries to the shoulder and upper arm	0.766	0.234
F41 Other anxiety disorders	0.765	0.235
F17 Mental and behavioural disorders due to use of tobacco	0.763	0.237
I72 Other aneurysm	0.763	0.237
F00-F09 Organic, including symptomatic, mental disorders	0.761	0.239
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.759	0.241
I67.2 Cerebral atherosclerosis	0.758	0.242
T46 Poisoning by agents primarily affecting the cardiovascular system	0.758	0.242
G93 Other disorders of brain	0.757	0.243
J80 Adult respiratory distress syndrome	0.757	0.243
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.757	0.243
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.756	0.244
J09-J18 Influenza and pneumonia	0.754	0.246
E83 Disorders of mineral metabolism	0.753	0.247
Y48 Anaesthetics and therapeutic gases	0.753	0.247
M24.2 Disorder of ligament	0.751	0.249
S50-S59 Injuries to the elbow and forearm	0.749	0.251
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.749	0.251
V40-V49 Car occupant injured in transport accident	0.749	0.251
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.749	0.251
F80-F89 Disorders of psychological development	0.748	0.252
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.747	0.253
J43 Emphysema	0.744	0.255
F10.4 Withdrawal state with delirium	0.744	0.256
R03 Abnormal blood-pressure reading, without diagnosis	0.741	0.259
Y43 Primarily systemic agents	0.740	0.260
M25.6 Stiffness of joint, not elsewhere classified	0.740	0.260
E87.5 Hyperkalaemia	0.739	0.261
G40-G47 Episodic and paroxysmal disorders	0.738	0.262
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.738	0.262
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.737	0.263
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.737	0.263
J60-J70 Lung diseases due to external agents	0.736	0.264
B34 Viral infection of unspecified site	0.736	0.264
E20-E35 Disorders of other endocrine glands	0.736	0.264
E87.2 Acidosis	0.735	0.265
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.735	0.265
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.733	0.267
R00.8 Other and unspecified abnormalities of heart beat	0.733	0.267
I61 Intracerebral haemorrhage	0.732	0.268
H44 Disorders of globe	0.732	0.268
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.731	0.269
M25.3 Other instability of joint	0.729	0.271
Y40 Systemic antibiotics	0.729	0.271
E83.5 Disorders of calcium metabolism	0.729	0.271
M24.4 Recurrent dislocation and subluxation of joint	0.726	0.274
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.725	0.275
F60-F69 Disorders of adult personality and behaviour	0.724	0.276
W50-W64 Exposure to animate mechanical forces	0.722	0.278
G30-G32 Other degenerative diseases of the nervous system	0.722	0.278
M91-M94 Chondropathies	0.721	0.279
M60-M63 Disorders of muscles	0.719	0.281
F99-F99 Unspecified mental disorder	0.719	0.281
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.718	0.282
X60-X84 Intentional self-harm	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
J41 Simple and mucopurulent chronic bronchitis	0.717	0.283
F44 Dissociative [conversion] disorders	0.716	0.284
R95-R99 Ill-defined and unknown causes of mortality	0.716	0.284
J37 Chronic laryngitis and laryngotracheitis	0.715	0.285
T33-T35 Frostbite	0.713	0.287
T26-T28 Burns and corrosions confined to eye and internal organs	0.713	0.287
T20-T25 Burns and corrosions of external body surface, specified by site	0.713	0.287
T00-T07 Injuries involving multiple body regions	0.713	0.287
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.712	0.288
I73.9 Peripheral vascular disease, unspecified	0.712	0.288
S70-S79 Injuries to the hip and thigh	0.711	0.289
J45 Asthma	0.708	0.292
M34.9 Systemic sclerosis, unspecified	0.708	0.292
J30 Vasomotor and allergic rhinitis	0.708	0.292
T51 Toxic effect of alcohol	0.706	0.294
F41.2 Mixed anxiety and depressive disorder	0.706	0.294
X20-X29 Contact with venomous animals and plants	0.705	0.295
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.705	0.295
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.705	0.295
F70-F79 Mental retardation	0.705	0.295
T88 Other complications of surgical and medical care, not elsewhere classified	0.704	0.296
H11 Other disorders of conjunctiva	0.704	0.296
I27 Other pulmonary heart diseases	0.703	0.297
H57 Other disorders of eye and adnexa	0.702	0.298
I00-I02 Acute rheumatic fever	0.701	0.298
J90-J94 Other diseases of pleura	0.701	0.299
F10.9 Unspecified mental and behavioural disorder	0.700	0.300
H43 Disorders of vitreous body	0.700	0.300
J00 Acute nasopharyngitis [common cold]	0.700	0.300
S60-S69 Injuries to the wrist and hand	0.699	0.301
J96 Respiratory failure, not elsewhere classified	0.699	0.301
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.698	0.302
X40-X49 Accidental poisoning by and exposure to noxious substances	0.697	0.302
B37 Candidiasis	0.697	0.303
J82 Pulmonary eosinophilia, not elsewhere classified	0.697	0.303
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.697	0.303
M31 Other necrotising vasculopathies	0.697	0.303
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.696	0.304
S06.3 Focal brain injury	0.695	0.305
I68 Cerebrovascular disorders in diseases classified elsewhere	0.695	0.305
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.695	0.305
I77 Other disorders of arteries and arterioles	0.695	0.305
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.695	0.305
G35-G37 Demyelinating diseases of the central nervous system	0.694	0.306
M00-M03 Infectious arthropathies	0.694	0.306
H47 Other disorders of optic [2nd] nerve and visual pathways	0.694	0.306
M67 Other disorders of synovium and tendon	0.694	0.306
M34.1 CR(E)ST syndrome	0.694	0.306
S05 Injury of eye and orbit	0.693	0.307
G95 Other diseases of spinal cord	0.692	0.308
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.692	0.308
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.691	0.309
T85 Complications of other internal prosthetic devices, implants and grafts	0.690	0.310
T15-T19 Effects of foreign body entering through natural orifice	0.690	0.310
I73.8 Other specified peripheral vascular diseases	0.689	0.310
I73.1 Thromboangiitis obliterans [Buerger]	0.689	0.310
Y49 Psychotropic drugs, not elsewhere classified	0.689	0.311
L89 Decubitus ulcer	0.689	0.311
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.688	0.312
M33 Dermatopolymyositis	0.688	0.312
M32 Systemic lupus erythematosus	0.688	0.312
M30 Polyarteritis nodosa and related conditions	0.688	0.312
M21 Other acquired deformities of limbs	0.688	0.312
X50-X57 Overexertion, travel and privation	0.686	0.314
Y41 Other systemic anti-infectives and antiparasitics	0.686	0.314
I67.7 Cerebral arteritis, not elsewhere classified	0.685	0.315
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.685	0.315
I67.5 Moyamoya disease	0.685	0.315
I67.4 Hypertensive encephalopathy	0.685	0.315
I67.3 Progressive vascular leukoencephalopathy	0.685	0.315
I67.0 Dissection of cerebral arteries, nonruptured	0.685	0.315
V20-V29 Motorcycle rider injured in transport accident	0.685	0.315
S06.6 Traumatic subarachnoid haemorrhage	0.685	0.315
J84.0 Alveolar and parietoalveolar conditions	0.685	0.315
Y60-Y69 Misadventures to patients during surgical and medical care	0.685	0.315
M40-M43 Deforming dorsopathies	0.685	0.315
J32.9 Chronic sinusitis, unspecified	0.684	0.316
R01.2 Other cardiac sounds	0.684	0.316
R01.0 Benign and innocent cardiac murmurs	0.684	0.316
F12 Mental and behavioural disorders due to use of cannabinoids	0.684	0.316
J98.9 Respiratory disorder, unspecified	0.683	0.317
J98.6 Disorders of diaphragm	0.683	0.317
J98.5 Diseases of mediastinum, not elsewhere classified	0.683	0.317
J98.3 Compensatory emphysema	0.683	0.317
J98.2 Interstitial emphysema	0.683	0.317
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.683	0.317
M24.9 Joint derangement, unspecified	0.680	0.320
M24.7 Protrusio acetabuli	0.680	0.320
M24.6 Ankylosis of joint	0.680	0.320
M24.5 Contracture of joint	0.680	0.320
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.680	0.320
S32 Fracture of lumbar spine and pelvis	0.679	0.320
A50-A64 Infections with a predominantly sexual mode of transmission	0.678	0.321
L90 Atrophic disorders of skin	0.677	0.323
B99-B99 Other infectious diseases	0.677	0.323
B90-B94 Sequelae of infectious and parasitic diseases	0.677	0.323
B85-B89 Pediculosis, acariasis and other infestations	0.677	0.323
B65-B83 Helminthiases	0.677	0.323
B50-B64 Protozoal diseases	0.677	0.323
B20-B24 Human immunodeficiency virus [HIV] disease	0.677	0.323
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.677	0.323
A75-A79 Rickettsioses	0.677	0.323
A70-A74 Other diseases caused by chlamydiae	0.677	0.323
A65-A69 Other spirochaetal diseases	0.677	0.323
A20-A28 Certain zoonotic bacterial diseases	0.677	0.323
A15-A19 Tuberculosis	0.677	0.323
M47.1 Other spondylosis with myelopathy	0.677	0.323
H02 Other disorders of eyelid	0.676	0.324
M25.5 Pain in joint	0.676	0.324
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.674	0.326
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.673	0.327
B34.9 Viral infection, unspecified	0.673	0.327
R04.9 Haemorrhage from respiratory passages, unspecified	0.672	0.327
R04.8 Haemorrhage from other sites in respiratory passages	0.672	0.327
R04.1 Haemorrhage from throat	0.672	0.327
M24.01 Loose body in joint (Shoulder region)	0.672	0.328
G93.6 Cerebral oedema	0.672	0.328
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.672	0.328
F18 Mental and behavioural disorders due to use of volatile solvents	0.672	0.328
F16 Mental and behavioural disorders due to use of hallucinogens	0.672	0.328
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.672	0.328
F14 Mental and behavioural disorders due to use of cocaine	0.672	0.328
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.672	0.328
F11 Mental and behavioural disorders due to use of opioids	0.672	0.328
J05 Acute obstructive laryngitis [croup] and epiglottitis	0.671	0.329
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.670	0.330
Y35-Y36 Legal intervention and operations of war	0.670	0.330
Y10-Y34 Event of undetermined intent	0.670	0.330
Y00-Y09 Assault	0.670	0.330
X85-X99 Assault	0.670	0.330
X58-X59 Accidental exposure to other and unspecified factors	0.670	0.330
X30-X39 Exposure to forces of nature	0.670	0.330
X10-X19 Contact with heat and hot substances	0.670	0.330
X00-X09 Exposure to smoke, fire and flames	0.670	0.330
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.670	0.330
W75-W84 Other accidental threats to breathing	0.670	0.330
W65-W74 Accidental drowning and submersion	0.670	0.330
V98-V99 Other and unspecified transport accidents	0.670	0.330
V95-V97 Air and space transport accidents	0.670	0.330
V90-V94 Water transport accidents	0.670	0.330
V80-V89 Other land transport accidents	0.670	0.330
V70-V79 Bus occupant injured in transport accident	0.670	0.330
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.670	0.330
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.670	0.330
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.670	0.330
V01-V09 Pedestrian injured in transport accident	0.670	0.330
R91 Abnormal findings on diagnostic imaging of lung	0.670	0.330
I71.8 Aortic aneurysm of unspecified site, ruptured	0.669	0.331
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.669	0.331
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.669	0.331
I71.1 Thoracic aortic aneurysm, ruptured	0.669	0.331
I71.0 Dissection of aorta [any part]	0.669	0.331
J95 Postprocedural respiratory disorders, not elsewhere classified	0.669	0.331
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.668	0.331
W20-W49 Exposure to inanimate mechanical forces	0.666	0.334
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.666	0.334
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.666	0.334
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.666	0.334
T41 Poisoning by anaesthetics and therapeutic gases	0.666	0.334
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.666	0.334
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.666	0.334
T36 Poisoning by systemic antibiotics	0.666	0.334
B15-B19 Viral hepatitis	0.666	0.334
M89 Other disorders of bone	0.666	0.334
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.666	0.334
I70 Atherosclerosis	0.664	0.335
L80 Vitiligo	0.664	0.336
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.664	0.336
M47.92 Spondylosis, unspecified (Cervical region)	0.664	0.336
R45 Symptoms and signs involving emotional state	0.662	0.338
G00-G09 Inflammatory diseases of the central nervous system	0.662	0.338
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.660	0.339
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.660	0.340
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.660	0.340
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.659	0.341
T91 Sequelae of injuries of neck and trunk	0.658	0.342
T40.4 Other synthetic narcotics	0.658	0.342
M24.11 Other articular cartilage disorders (Shoulder region)	0.658	0.342
Y48.3 Local anaesthetics	0.658	0.342
R06.7 Sneezing	0.657	0.343
R06.6 Hiccough	0.657	0.343
R06.3 Periodic breathing	0.657	0.343
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.656	0.344
Chapter VIII Diseases of the ear and mastoid process	0.655	0.344
Y57 Other and unspecified drugs and medicaments	0.654	0.346
H53-H54 Visual disturbances and blindness	0.654	0.346
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.654	0.346
M24.19 Other articular cartilage disorders (Site unspecified)	0.654	0.346
M24.18 Other articular cartilage disorders (Other)	0.654	0.346
M24.17 Other articular cartilage disorders (Ankle and foot)	0.654	0.346
M24.14 Other articular cartilage disorders (Hand)	0.654	0.346
M24.13 Other articular cartilage disorders (Forearm)	0.654	0.346
M24.12 Other articular cartilage disorders (Upper arm)	0.654	0.346
M24.10 Other articular cartilage disorders (Multiple sites)	0.654	0.346
H25-H28 Disorders of lens	0.653	0.347
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.653	0.347
S08 Traumatic amputation of part of head	0.652	0.347
S07 Crushing injury of head	0.652	0.347
S04 Injury of cranial nerves	0.652	0.347
S03 Dislocation, sprain and strain of joints and ligaments of head	0.652	0.347
R05 Cough	0.652	0.348
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.652	0.348
S37 Injury of urinary and pelvic organs	0.652	0.348
S36 Injury of intra-abdominal organs	0.652	0.348
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.652	0.348
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.652	0.348
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.652	0.348
S31 Open wound of abdomen, lower back and pelvis	0.652	0.348
G40 Epilepsy	0.651	0.349
J02 Acute pharyngitis	0.651	0.349
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.650	0.350
M88 Paget's disease of bone [osteitis deformans]	0.650	0.350
T93 Sequelae of injuries of lower limb	0.650	0.350
B97 Viral agents as the cause of diseases classified to other chapters	0.650	0.350
E87.0 Hyperosmolality and hypernatraemia	0.650	0.350
H44.2 Degenerative myopia	0.650	0.350
Y44 Agents primarily affecting blood constituents	0.649	0.350
G50-G59 Nerve, nerve root and plexus disorders	0.649	0.351
R87 Abnormal findings in specimens from female genital organs	0.648	0.351
F43.1 Posttraumatic stress disorder	0.648	0.352
R85 Abnormal findings in specimens from digestive organs and abdominal cavity	0.648	0.352
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.647	0.353
J34.3 Hypertrophy of nasal turbinates	0.647	0.353
J45.0 Predominantly allergic asthma	0.647	0.353
I05-I09 Chronic rheumatic heart diseases	0.646	0.354
A80-A89 Viral infections of the central nervous system	0.644	0.355
M25.7 Osteophyte	0.645	0.355
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.643	0.357
I27.0 Primary pulmonary hypertension	0.643	0.357
L94 Other localised connective tissue disorders	0.640	0.360
Q60-Q64 Congenital malformations of the urinary system	0.640	0.360
Q20-Q28 Congenital malformations of the circulatory system	0.640	0.360
F17.1 Harmful use	0.640	0.360
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.640	0.360
T92 Sequelae of injuries of upper limb	0.640	0.360
G80-G83 Cerebral palsy and other paralytic syndromes	0.640	0.360
T79-T79 Certain early complications of trauma	0.639	0.361
L85 Other epidermal thickening	0.638	0.362
J39 Other diseases of upper respiratory tract	0.637	0.362
Y43.3 Other antineoplastic drugs	0.637	0.363
S06.2 Diffuse brain injury	0.636	0.364
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.636	0.364
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.635	0.365
Y59 Other and unspecified vaccines and biological substances	0.635	0.365
Y58 Bacterial vaccines	0.635	0.365
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.635	0.365
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.635	0.365
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.635	0.365
Y53 Agents primarily affecting the gastro-intestinal system	0.635	0.365
Y50 Central nervous system stimulants, not elsewhere classified	0.635	0.365
Y47 Sedatives, hypnotics and antianxiety drugs	0.635	0.365
Y46 Antiepileptics and anti-Parkinsonism drugs	0.635	0.365
F48 Other neurotic disorders	0.635	0.365
F42 Obsessive-compulsive disorder	0.635	0.365
G93.9 Disorder of brain, unspecified	0.634	0.366
E83.3 Disorders of phosphorus metabolism	0.634	0.366
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.634	0.366
V10-V19 Pedal cyclist injured in transport accident	0.634	0.366
F10.8 Other mental and behavioural disorders	0.634	0.366
F10.7 Residual and late-onset psychotic disorder	0.634	0.366
F10.6 Amnesic syndrome	0.634	0.366
F10.5 Psychotic disorder	0.634	0.366
R06.2 Wheezing	0.634	0.366
J34.0 Abscess, furuncle and carbuncle of nose	0.633	0.366
G43 Migraine	0.634	0.366
F33 Recurrent depressive disorder	0.633	0.367
S90-S99 Injuries to the ankle and foot	0.633	0.367
S02 Fracture of skull and facial bones	0.633	0.367
I69.3 Sequelae of cerebral infarction	0.632	0.368
G93.0 Cerebral cysts	0.632	0.368
Q00-Q07 Congenital malformations of the nervous system	0.631	0.369
F31 Bipolar affective disorder	0.631	0.369
S80-S89 Injuries to the knee and lower leg	0.631	0.369
L92 Granulomatous disorders of skin and subcutaneous tissue	0.631	0.369
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.630	0.370
S20-S29 Injuries to the thorax	0.629	0.371
M25.51 Pain in joint (Shoulder region)	0.629	0.371
J99.1 Respiratory disorders in other diffuse connective tissue disorders	0.628	0.372
I69.1 Sequelae of intracerebral haemorrhage	0.627	0.373
E86 Volume depletion	0.627	0.373
M20 Acquired deformities of fingers and toes	0.627	0.373
M49 Spondylopathies in diseases classified elsewhere	0.626	0.373
T46.1 Calcium-channel blockers	0.626	0.374
B35 Dermatophytosis	0.625	0.375
G96 Other disorders of central nervous system	0.625	0.375
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.624	0.376
J21 Acute bronchiolitis	0.624	0.376
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.623	0.377
Y52 Agents primarily affecting the cardiovascular system	0.623	0.377
S09.8 Other specified injuries of head	0.622	0.378
S09.7 Multiple injuries of head	0.622	0.378
S09.2 Traumatic rupture of ear drum	0.622	0.378
S09.1 Injury of muscle and tendon of head	0.622	0.378
S09.0 Injury of blood vessels of head, not elsewhere classified	0.622	0.378
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.622	0.378
T40.8 Lysergide [LSD]	0.622	0.378
T40.7 Cannabis (derivatives)	0.622	0.378
T40.6 Other and unspecified narcotics	0.622	0.378
T40.5 Cocaine	0.622	0.378
T40.3 Methadone	0.622	0.378
T40.1 Heroin	0.622	0.378
T40.0 Opium	0.622	0.378
G70-G73 Diseases of myoneural junction and muscle	0.620	0.379
M67.8 Other specified disorders of synovium and tendon	0.620	0.380
R47 Speech disturbances, not elsewhere classified	0.620	0.380
F10.2 Dependence syndrome	0.618	0.382
H02.1 Ectropion of eyelid	0.617	0.383
R27 Other lack of coordination	0.617	0.383
T98 Sequelae of other and unspecified effects of external causes	0.617	0.383
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension	0.616	0.384
S10 Superficial injury of neck	0.616	0.384
M86 Osteomyelitis	0.615	0.385
V49 Car occupant injured in other and unspecified transport accidents	0.615	0.385
B37.0 Candidal stomatitis	0.615	0.385
M25.9 Joint disorder, unspecified	0.615	0.385
Chapter XI Diseases of the digestive system	0.615	0.385
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.614	0.386
Q80-Q89 Other congenital malformations	0.614	0.386
M47.99 Spondylosis, unspecified (Site unspecified)	0.613	0.387
G95.2 Cord compression, unspecified	0.612	0.387
H02.9 Disorder of eyelid, unspecified	0.612	0.388
M25.2 Flail joint	0.612	0.388

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations