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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs73116718
log Bayes Factor = 18.3781
Chromosome 3   position 78,952,189  (GRCh37) Explore rs73116718 on Ensembl!
Variant rs73116718 is part of Cluster X0150

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
0.999 0.001 0.000
Chapter VI Diseases of the nervous system
0.999 0.001 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.998 0.002 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.996 0.004 0.000
S00-S09 Injuries to the head
0.996 0.004 0.000
K55-K64 Other diseases of intestines
0.995 0.005 0.000
G40-G47 Episodic and paroxysmal disorders
0.993 0.007 0.000
E10-E14 Diabetes mellitus
0.989 0.011 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.985 0.015 0.000
E11 Non-insulin-dependent diabetes mellitus
0.980 0.020 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.979 0.021 0.000
Chapter V Mental and behavioural disorders
0.975 0.025 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.974 0.026 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.971 0.029 0.000
E11.9 Without complications
0.969 0.031 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.969 0.031 0.000
S09 Other and unspecified injuries of head
0.966 0.034 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.966 0.034 0.000
K50-K52 Noninfective enteritis and colitis
0.963 0.037 0.000
K62 Other diseases of anus and rectum
0.961 0.039 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.957 0.043 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.951 0.049 0.000
G40 Epilepsy
0.950 0.050 0.000
K70-K77 Diseases of liver
0.950 0.050 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.947 0.053 0.000
S01 Open wound of head
0.945 0.055 0.000
I25.2 Old myocardial infarction
0.945 0.055 0.000
S09.9 Unspecified injury of head
0.944 0.056 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.944 0.056 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.943 0.057 0.000
E70-E90 Metabolic disorders
0.942 0.058 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.940 0.060 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.934 0.066 0.000
I21 Acute myocardial infarction
0.932 0.068 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.930 0.070 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.929 0.071 0.000
Z93 Artificial opening status
0.928 0.072 0.000
L60-L75 Disorders of skin appendages
0.925 0.075 0.000
M70-M79 Other soft tissue disorders
0.922 0.078 0.000
K63 Other diseases of intestine
0.915 0.085 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.914 0.085 0.000
K51 Ulcerative colitis
0.913 0.087 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.908 0.092 0.000
K62.3 Rectal prolapse
0.897 0.103 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.895 0.105 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.895 0.105 0.000
K61 Abscess of anal and rectal regions
0.892 0.108 0.000
Z94 Transplanted organ and tissue status
0.890 0.110 0.000
M05-M14 Inflammatory polyarthropathies
0.889 0.111 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.888 0.112 0.000
S01.8 Open wound of other parts of head
0.887 0.113 0.000
K90-K93 Other diseases of the digestive system
0.886 0.113 0.000
Z83 Family history of other specific disorders
0.886 0.114 0.000
R04 Haemorrhage from respiratory passages
0.885 0.115 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.883 0.117 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.881 0.119 0.000
L72.1 Trichilemmal cyst
0.880 0.120 0.000
M75 Shoulder lesions
0.878 0.122 0.000
S80-S89 Injuries to the knee and lower leg
0.873 0.127 0.000
Chapter X Diseases of the respiratory system
0.873 0.127 0.000
S60-S69 Injuries to the wrist and hand
0.873 0.127 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.871 0.129 0.000
I21.9 Acute myocardial infarction, unspecified
0.870 0.130 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.870 0.130 0.000
K62.1 Rectal polyp
0.870 0.130 0.000
Z99.2 Dependence on renal dialysis
0.867 0.133 0.000
F30-F39 Mood [affective] disorders
0.866 0.134 0.000
Z90.8 Acquired absence of other organs
0.865 0.135 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.865 0.135 0.000
Z90.7 Acquired absence of genital organ(s)
0.862 0.138 0.000
F10.1 Harmful use
0.860 0.140 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.860 0.140 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.858 0.142 0.000
K52 Other non-infective gastro-enteritis and colitis
0.856 0.144 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.856 0.144 0.000
I85 Oesophageal varices
0.856 0.144 0.000
E10 Insulin-dependent diabetes mellitus
0.855 0.145 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.855 0.145 0.000
Z98 Other postsurgical states
0.854 0.146 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.846 0.154 0.000
I25.1 Atherosclerotic heart disease
0.843 0.157 0.000
K60 Fissure and fistula of anal and rectal regions
0.843 0.157 0.000
G40.9 Epilepsy, unspecified
0.843 0.157 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.842 0.158 0.000
K51.9 Ulcerative colitis, unspecified
0.839 0.161 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.836 0.164 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.835 0.165 0.000
E86 Volume depletion
0.835 0.165 0.000
S20-S29 Injuries to the thorax
0.835 0.165 0.000
K76 Other diseases of liver
0.830 0.170 0.000
K55 Vascular disorders of intestine
0.829 0.171 0.000
Z95.1 Presence of aortocoronary bypass graft
0.828 0.172 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.825 0.175 0.000
F10.3 Withdrawal state
0.820 0.180 0.000
I20 Angina pectoris
0.816 0.184 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.816 0.184 0.000
R06 Abnormalities of breathing
0.815 0.185 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.815 0.185 0.000
I83 Varicose veins of lower extremities
0.814 0.186 0.000
R02 Gangrene, not elsewhere classified
0.814 0.186 0.000
Z93.3 Colostomy status
0.811 0.189 0.000
R00 Abnormalities of heart beat
0.810 0.190 0.000
M75.4 Impingement syndrome of shoulder
0.809 0.191 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.807 0.193 0.000
K92 Other diseases of digestive system
0.807 0.193 0.000
Z94.0 Kidney transplant status
0.805 0.195 0.000
K70 Alcoholic liver disease
0.805 0.195 0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.804 0.196 0.000
S02 Fracture of skull and facial bones
0.803 0.197 0.000
G47 Sleep disorders
0.802 0.198 0.000
Z72 Problems related to lifestyle
0.801 0.199 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.801 0.199 0.000
J40-J47 Chronic lower respiratory diseases
0.800 0.200 0.000
Z95.0 Presence of cardiac pacemaker
0.800 0.200 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.799 0.201 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.797 0.203 0.000
K63.3 Ulcer of intestine
0.796 0.204 0.000
Chapter XX External causes of morbidity and mortality
0.796 0.204 0.000
L20-L30 Dermatitis and eczema
0.796 0.204 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.792 0.208 0.000
M06 Other rheumatoid arthritis
0.790 0.210 0.000
Z98.8 Other specified postsurgical states
0.789 0.211 0.000
F10.4 Withdrawal state with delirium
0.788 0.212 0.000
F10.2 Dependence syndrome
0.788 0.212 0.000
Chapter VII Diseases of the eye and adnexa
0.788 0.212 0.000
R04.2 Haemoptysis
0.787 0.213 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.786 0.214 0.000
T81 Complications of procedures, not elsewhere classified
0.785 0.215 0.000
T66-T78 Other and unspecified effects of external causes
0.784 0.216 0.000
S06 Intracranial injury
0.783 0.217 0.000
G70-G73 Diseases of myoneural junction and muscle
0.782 0.217 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.782 0.218 0.000
G43 Migraine
0.780 0.220 0.000
S82 Fracture of lower leg, including ankle
0.780 0.220 0.000
E11.4 With neurological complications
0.779 0.221 0.000
G30-G32 Other degenerative diseases of the nervous system
0.777 0.223 0.000
E83 Disorders of mineral metabolism
0.776 0.224 0.000
K61.0 Anal abscess
0.776 0.224 0.000
K62.8 Other specified diseases of anus and rectum
0.776 0.224 0.000
G20-G26 Extrapyramidal and movement disorders
0.776 0.224 0.000
K60.2 Anal fissure, unspecified
0.775 0.225 0.000
I05-I09 Chronic rheumatic heart diseases
0.774 0.226 0.000
Z83.5 Family history of eye and ear disorders
0.774 0.226 0.000
R04.0 Epistaxis
0.773 0.227 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.771 0.229 0.000
M13 Other arthritis
0.771 0.229 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.770 0.230 0.000
Z90.0 Acquired absence of part of head and neck
0.769 0.231 0.000
Z97 Presence of other devices
0.769 0.231 0.000
M75.5 Bursitis of shoulder
0.768 0.232 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.768 0.232 0.000
K63.5 Polyp of colon
0.767 0.233 0.000
I86 Varicose veins of other sites
0.766 0.234 0.000
I21.4 Acute subendocardial myocardial infarction
0.766 0.234 0.000
G51 Facial nerve disorders
0.766 0.234 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.764 0.236 0.000
S90-S99 Injuries to the ankle and foot
0.763 0.237 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.763 0.237 0.000
D50-D53 Nutritional anaemias
0.762 0.238 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.762 0.238 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.762 0.238 0.000
M86-M90 Other osteopathies
0.761 0.239 0.000
K62.7 Radiation proctitis
0.760 0.240 0.000
E40-E46 Malnutrition
0.759 0.241 0.000
I25.5 Ischaemic cardiomyopathy
0.758 0.241 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.757 0.243 0.000
Z93.2 Ileostomy status
0.756 0.244 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.755 0.245 0.000
Z89 Acquired absence of limb
0.752 0.248 0.000
I84 Haemorrhoids
0.752 0.248 0.000
D60-D64 Aplastic and other anaemias
0.751 0.249 0.000
G44 Other headache syndromes
0.749 0.251 0.000
M79.8 Other specified soft tissue disorders
0.748 0.252 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.748 0.252 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.747 0.252 0.000
I22 Subsequent myocardial infarction
0.747 0.253 0.000
S70-S79 Injuries to the hip and thigh
0.747 0.253 0.000
K76.9 Liver disease, unspecified
0.747 0.253 0.000
I85.9 Oesophageal varices without bleeding
0.747 0.253 0.000
J43 Emphysema
0.745 0.255 0.000
R07 Pain in throat and chest
0.745 0.255 0.000
E20-E35 Disorders of other endocrine glands
0.744 0.255 0.000
T82.1 Mechanical complication of cardiac electronic device
0.744 0.256 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.742 0.258 0.000
K74 Fibrosis and cirrhosis of liver
0.742 0.258 0.000
F32 Depressive episode
0.741 0.259 0.000
S01.0 Open wound of scalp
0.740 0.260 0.000
E78.5 Hyperlipidaemia, unspecified
0.740 0.260 0.000
K62.4 Stenosis of anus and rectum
0.740 0.260 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.739 0.261 0.000
F99-F99 Unspecified mental disorder
0.738 0.262 0.000
Z90.1 Acquired absence of breast(s)
0.734 0.266 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.733 0.267 0.000
E11.3 With ophthalmic complications
0.733 0.267 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.732 0.268 0.000
E10.3 With ophthalmic complications
0.732 0.268 0.000
I20.0 Unstable angina
0.731 0.269 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.731 0.269 0.000
F60-F69 Disorders of adult personality and behaviour
0.731 0.269 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.731 0.269 0.000
K61.3 Ischiorectal abscess
0.731 0.269 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.730 0.270 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.730 0.270 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.730 0.270 0.000
Z90.5 Acquired absence of kidney
0.730 0.270 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.729 0.271 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.729 0.271 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.728 0.272 0.000
M75.3 Calcific tendinitis of shoulder
0.728 0.272 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.726 0.274 0.000
K75 Other inflammatory liver diseases
0.726 0.274 0.000
R21 Rash and other nonspecific skin eruption
0.725 0.275 0.000
K51.2 Ulcerative (chronic) proctitis
0.725 0.275 0.000
L73 Other follicular disorders
0.724 0.276 0.000
G45.4 Transient global amnesia
0.723 0.277 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.723 0.277 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.722 0.278 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.722 0.278 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.722 0.278 0.000
S00 Superficial injury of head
0.721 0.279 0.000
K72 Hepatic failure, not elsewhere classified
0.720 0.280 0.000
Z72.1 Alcohol use
0.718 0.282 0.000
Z93.1 Gastrostomy status
0.718 0.282 0.000
K62.6 Ulcer of anus and rectum
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.3 Aneurysm of heart
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
Z84 Family history of other conditions
0.716 0.284 0.000
Z81 Family history of mental and behavioural disorders
0.716 0.284 0.000
T43.2 Other and unspecified antidepressants
0.715 0.285 0.000
S08 Traumatic amputation of part of head
0.714 0.286 0.000
S07 Crushing injury of head
0.714 0.286 0.000
S05 Injury of eye and orbit
0.714 0.286 0.000
S04 Injury of cranial nerves
0.714 0.286 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.714 0.286 0.000
S01.5 Open wound of lip and oral cavity
0.714 0.286 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.713 0.287 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.712 0.288 0.000
G41 Status epilepticus
0.712 0.288 0.000
E88 Other metabolic disorders
0.712 0.288 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.712 0.288 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.712 0.288 0.000
E11.5 With peripheral circulatory complications
0.711 0.289 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.710 0.289 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.710 0.290 0.000
E13 Other specified diabetes mellitus
0.709 0.291 0.000
E12 Malnutrition-related diabetes mellitus
0.709 0.291 0.000
F33 Recurrent depressive disorder
0.709 0.291 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.709 0.291 0.000
J43.9 Emphysema, unspecified
0.706 0.294 0.000
Z83.7 Family history of diseases of the digestive system
0.705 0.295 0.000
K51.8 Other ulcerative colitis
0.703 0.297 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.703 0.297 0.000
Chapter XXII Codes for special purposes
0.703 0.297 0.000
E11.8 With unspecified complications
0.703 0.297 0.000
E11.7 With multiple complications
0.703 0.297 0.000
E11.6 With other specified complications
0.703 0.297 0.000
E11.2 With renal complications
0.703 0.297 0.000
E11.1 With ketoacidosis
0.703 0.297 0.000
E11.0 With coma
0.703 0.297 0.000
G51.0 Bell's palsy
0.702 0.297 0.000
Z82.3 Family history of stroke
0.702 0.298 0.000
E50-E64 Other nutritional deficiencies
0.701 0.299 0.000
K56.5 Intestinal adhesions [bands] with obstruction
0.701 0.299 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.701 0.299 0.000
E10.1 With ketoacidosis
0.701 0.299 0.000
Z03.8 Observation for other suspected diseases and conditions
0.700 0.300 0.000
K57 Diverticular disease of intestine
0.699 0.301 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.699 0.301 0.000
F80-F89 Disorders of psychological development
0.699 0.301 0.000
F70-F79 Mental retardation
0.699 0.301 0.000
L10-L14 Bullous disorders
0.699 0.301 0.000
M05 Seropositive rheumatoid arthritis
0.697 0.302 0.000
M71 Other bursopathies
0.697 0.303 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.696 0.304 0.000
T39.1 4-Aminophenol derivatives
0.696 0.304 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.696 0.304 0.000
G47.3 Sleep apnoea
0.696 0.304 0.000
K63.1 Perforation of intestine (nontraumatic)
0.695 0.305 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.695 0.305 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.695 0.305 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.695 0.305 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.695 0.305 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.695 0.305 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.695 0.305 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.695 0.305 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.695 0.305 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.695 0.305 0.000
T36 Poisoning by systemic antibiotics
0.695 0.305 0.000
I85.0 Oesophageal varices with bleeding
0.694 0.305 0.000
K63.9 Disease of intestine, unspecified
0.694 0.306 0.000
S68 Traumatic amputation of wrist and hand
0.694 0.306 0.000
I82 Other venous embolism and thrombosis
0.693 0.306 0.000
S01.2 Open wound of nose
0.693 0.307 0.000
R00.1 Bradycardia, unspecified
0.693 0.307 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.693 0.307 0.000
R06.0 Dyspnoea
0.693 0.307 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.693 0.307 0.000
S09.8 Other specified injuries of head
0.692 0.307 0.000
S09.7 Multiple injuries of head
0.692 0.307 0.000
S09.2 Traumatic rupture of ear drum
0.692 0.307 0.000
S09.1 Injury of muscle and tendon of head
0.692 0.307 0.000
S09.0 Injury of blood vessels of head, not elsewhere classified
0.692 0.307 0.000
K55.9 Vascular disorder of intestine, unspecified
0.692 0.308 0.000
Z95.3 Presence of xenogenic heart valve
0.692 0.308 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.691 0.309 0.000
E83.5 Disorders of calcium metabolism
0.691 0.309 0.000
E78.0 Pure hypercholesterolaemia
0.691 0.309 0.000
Z30 Contraceptive management
0.691 0.309 0.000
Chapter I Certain infectious and parasitic diseases
0.691 0.309 0.000
Z95.4 Presence of other heart-valve replacement
0.691 0.309 0.000
S50-S59 Injuries to the elbow and forearm
0.690 0.310 0.000
L08 Other local infections of skin and subcutaneous tissue
0.689 0.310 0.000
E78.8 Other disorders of lipoprotein metabolism
0.689 0.310 0.000
Z13 Special screening examination for other diseases and disorders
0.689 0.311 0.000
K62.2 Anal prolapse
0.689 0.311 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.689 0.311 0.000
Z90.3 Acquired absence of part of stomach
0.688 0.312 0.000
M13.9 Arthritis, unspecified
0.687 0.313 0.000
I88 Nonspecific lymphadenitis
0.686 0.313 0.000
I87 Other disorders of veins
0.686 0.313 0.000
I81 Portal vein thrombosis
0.686 0.313 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.686 0.314 0.000
L50-L54 Urticaria and erythema
0.686 0.314 0.000
S01.1 Open wound of eyelid and periocular area
0.686 0.314 0.000
J09-J18 Influenza and pneumonia
0.686 0.314 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.684 0.316 0.000
I10-I15 Hypertensive diseases
0.683 0.317 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.682 0.318 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.682 0.318 0.000
R20 Disturbances of skin sensation
0.682 0.318 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.682 0.318 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.682 0.318 0.000
G40.8 Other epilepsy
0.681 0.319 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.681 0.319 0.000
G40.5 Special epileptic syndromes
0.681 0.319 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.681 0.319 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.681 0.319 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.681 0.319 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.681 0.319 0.000
J44 Other chronic obstructive pulmonary disease
0.681 0.319 0.000
K77 Liver disorders in diseases classified elsewhere
0.681 0.319 0.000
K73 Chronic hepatitis, not elsewhere classified
0.681 0.319 0.000
K71 Toxic liver disease
0.681 0.319 0.000
G57 Mononeuropathies of lower limb
0.681 0.319 0.000
M77 Other enthesopathies
0.680 0.320 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.680 0.320 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.679 0.320 0.000
I24 Other acute ischaemic heart diseases
0.679 0.321 0.000
E10.4 With neurological complications
0.678 0.322 0.000
S01.7 Multiple open wounds of head
0.678 0.322 0.000
S01.4 Open wound of cheek and temporomandibular area
0.678 0.322 0.000
S01.3 Open wound of ear
0.678 0.322 0.000
E14 Unspecified diabetes mellitus
0.677 0.323 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.677 0.323 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.677 0.323 0.000
T87 Complications peculiar to reattachment and amputation
0.677 0.323 0.000
T86 Failure and rejection of transplanted organs and tissues
0.677 0.323 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.677 0.323 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.676 0.324 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.676 0.324 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.676 0.324 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.676 0.324 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.676 0.324 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.676 0.324 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.676 0.324 0.000
F11 Mental and behavioural disorders due to use of opioids
0.676 0.324 0.000
E85 Amyloidosis
0.676 0.324 0.000
E84 Cystic fibrosis
0.676 0.324 0.000
E79 Disorders of purine and pyrimidine metabolism
0.676 0.324 0.000
E77 Disorders of glycoprotein metabolism
0.676 0.324 0.000
E76 Disorders of glycosaminoglycan metabolism
0.676 0.324 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.676 0.324 0.000
E74 Other disorders of carbohydrate metabolism
0.676 0.324 0.000
E73 Lactose intolerance
0.676 0.324 0.000
E72 Other disorders of amino-acid metabolism
0.676 0.324 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.676 0.324 0.000
E70 Disorders of aromatic amino-acid metabolism
0.676 0.324 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.676 0.324 0.000
S01.9 Open wound of head, part unspecified
0.675 0.325 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.675 0.325 0.000
D50 Iron deficiency anaemia
0.674 0.326 0.000
M91-M94 Chondropathies
0.674 0.326 0.000
M60-M63 Disorders of muscles
0.674 0.326 0.000
M00-M03 Infectious arthropathies
0.674 0.326 0.000
S27 Injury of other and unspecified intrathoracic organs
0.672 0.328 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.670 0.330 0.000
G45.3 Amaurosis fugax
0.670 0.330 0.000
G45.2 Multiple and bilateral precerebral artery syndromes
0.670 0.330 0.000
G45.1 Carotid artery syndrome (hemispheric)
0.670 0.330 0.000
G45.0 Vertebro-basilar artery syndrome
0.670 0.330 0.000
M06.4 Inflammatory polyarthropathy
0.670 0.330 0.000
T93 Sequelae of injuries of lower limb
0.669 0.331 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.668 0.332 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.668 0.332 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.668 0.332 0.000
R01 Cardiac murmurs and other cardiac sounds
0.668 0.332 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.668 0.332 0.000
E65-E68 Obesity and other hyperalimentation
0.667 0.333 0.000
R07.4 Chest pain, unspecified
0.667 0.333 0.000
S82.5 Fracture of medial malleolus
0.667 0.333 0.000
F10.9 Unspecified mental and behavioural disorder
0.666 0.333 0.000
F10.8 Other mental and behavioural disorders
0.666 0.333 0.000
F10.7 Residual and late-onset psychotic disorder
0.666 0.333 0.000
F10.6 Amnesic syndrome
0.666 0.333 0.000
F10.5 Psychotic disorder
0.666 0.333 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.666 0.334 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.666 0.334 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.666 0.334 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.666 0.334 0.000
Z82.2 Family history of deafness and hearing loss
0.666 0.334 0.000
Z82.1 Family history of blindness and visual loss
0.666 0.334 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.666 0.334 0.000
S89 Other and unspecified injuries of lower leg
0.665 0.335 0.000
M79.6 Pain in limb
0.665 0.335 0.000
Z93.9 Artificial opening status, unspecified
0.665 0.335 0.000
Z93.8 Other artificial opening status
0.665 0.335 0.000
Z93.5 Cystostomy status
0.665 0.335 0.000
Z93.0 Tracheostomy status
0.665 0.335 0.000
H30-H36 Disorders of choroid and retina
0.664 0.336 0.000
L75 Apocrine sweat disorders
0.663 0.337 0.000
L74 Eccrine sweat disorders
0.663 0.337 0.000
L70 Acne
0.663 0.337 0.000
L68 Hypertrichosis
0.663 0.337 0.000
L67 Hair colour and hair shaft abnormalities
0.663 0.337 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.663 0.337 0.000
L65 Other nonscarring hair loss
0.663 0.337 0.000
L64 Androgenic alopecia
0.663 0.337 0.000
L63 Alopecia areata
0.663 0.337 0.000
L62 Nail disorders in diseases classified elsewhere
0.663 0.337 0.000
G82 Paraplegia and tetraplegia
0.663 0.337 0.000
S40-S49 Injuries to the shoulder and upper arm
0.662 0.338 0.000
M76 Enthesopathies of lower limb, excluding foot
0.661 0.339 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.661 0.339 0.000
Z94.8 Other transplanted organ and tissue status
0.661 0.339 0.000
S61 Open wound of wrist and hand
0.661 0.339 0.000
G81 Hemiplegia
0.661 0.339 0.000
Z95.2 Presence of prosthetic heart valve
0.660 0.340 0.000
K62.9 Disease of anus and rectum, unspecified
0.659 0.341 0.000
S67 Crushing injury of wrist and hand
0.658 0.342 0.000
L71 Rosacea
0.658 0.342 0.000
M40-M43 Deforming dorsopathies
0.657 0.343 0.000
M06.9 Rheumatoid arthritis, unspecified
0.657 0.343 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.657 0.343 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.656 0.343 0.000
K63.4 Enteroptosis
0.656 0.344 0.000
K63.2 Fistula of intestine
0.656 0.344 0.000
K63.0 Abscess of intestine
0.656 0.344 0.000
Z99.9 Dependence on unspecified enabling machine and device
0.656 0.344 0.000
Z99.4 Dependence on artificial heart
0.656 0.344 0.000
Z99.1 Dependence on respirator
0.656 0.344 0.000
Z99.0 Dependence on aspirator
0.656 0.344 0.000
Z99.8 Dependence on other enabling machines and devices
0.655 0.344 0.000
I84.5 External haemorrhoids without complication
0.655 0.345 0.000
D64 Other anaemias
0.655 0.345 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.655 0.345 0.000
M65-M68 Disorders of synovium and tendon
0.655 0.345 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.655 0.345 0.000
K51.5 Mucosal proctocolitis
0.654 0.345 0.000
K51.4 Pseudopolyposis of colon
0.654 0.345 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.654 0.345 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.654 0.345 0.000
T51 Toxic effect of alcohol
0.654 0.345 0.000
T42.4 Benzodiazepines
0.654 0.346 0.000
R06.1 Stridor
0.653 0.347 0.000
M72 Fibroblastic disorders
0.653 0.347 0.000
K70.1 Alcoholic hepatitis
0.652 0.348 0.000
D50.8 Other iron deficiency anaemias
0.652 0.348 0.000
K76.6 Portal hypertension
0.648 0.352 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.646 0.354 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.646 0.354 0.000
S82.1 Fracture of upper end of tibia
0.645 0.354 0.000
R05 Cough
0.644 0.355 0.000
S20 Superficial injury of thorax
0.644 0.356 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.643 0.357 0.000
L72.8 Other follicular cysts of skin and subcutaneous tissue
0.642 0.358 0.000
L72.2 Steatocystoma multiplex
0.642 0.358 0.000
L84 Corns and callosities
0.642 0.358 0.000
Z73 Problems related to life-management difficulty
0.642 0.358 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.641 0.358 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.641 0.358 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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