TreeWAS – Variant ID: rs73153964

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T36-T50 Poisoning by drugs, medicaments and biological substances	1.000	0.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.999	0.001	0.000
S00-S09 Injuries to the head	0.989	0.011	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.986	0.014	0.000
T43.2 Other and unspecified antidepressants	0.972	0.028	0.000
S40-S49 Injuries to the shoulder and upper arm	0.971	0.029	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.967	0.033	0.000
S70-S79 Injuries to the hip and thigh	0.962	0.038	0.000
S42 Fracture of shoulder and upper arm	0.955	0.045	0.000
S02 Fracture of skull and facial bones	0.934	0.066	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.921	0.079	0.000
S70 Superficial injury of hip and thigh	0.917	0.083	0.000
T66-T78 Other and unspecified effects of external causes	0.909	0.091	0.000
S42.0 Fracture of clavicle	0.903	0.097	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.001	0.107	0.892
O60-O75 Complications of labour and delivery	0.000	0.110	0.890
S70.9 Superficial injury of hip and thigh, unspecified	0.885	0.115	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.885	0.115	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.000	0.118	0.882
T39.1 4-Aminophenol derivatives	0.880	0.120	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.000	0.123	0.877
S05 Injury of eye and orbit	0.874	0.126	0.000
T39.0 Salicylates	0.874	0.126	0.000
O70 Perineal laceration during delivery	0.000	0.127	0.873
O26 Maternal care for other conditions predominantly related to pregnancy	0.000	0.129	0.871
S20-S29 Injuries to the thorax	0.869	0.131	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.868	0.132	0.000
O70.1 Second degree perineal laceration during delivery	0.000	0.133	0.867
S42.00 Fracture of clavicle (closed)	0.866	0.134	0.000
O26.8 Other specified pregnancy-related conditions	0.000	0.134	0.866
T43.5 Other and unspecified antipsychotics and neuroleptics	0.864	0.136	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.863	0.137	0.000
S06 Intracranial injury	0.863	0.137	0.000
T78 Adverse effects, not elsewhere classified	0.856	0.144	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.853	0.147	0.000
I30-I52 Other forms of heart disease	0.849	0.151	0.000
Chapter IX Diseases of the circulatory system	0.846	0.154	0.000
I20-I25 Ischaemic heart diseases	0.844	0.156	0.000
S00 Superficial injury of head	0.841	0.159	0.000
I44 Atrioventricular and left bundle-branch block	0.840	0.160	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.835	0.165	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.834	0.166	0.000
I49 Other cardiac arrhythmias	0.834	0.166	0.000
S02.6 Fracture of mandible	0.832	0.168	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.832	0.168	0.000
S71 Open wound of hip and thigh	0.828	0.172	0.000
O72 Postpartum haemorrhage	0.000	0.172	0.828
I25 Chronic ischaemic heart disease	0.823	0.177	0.000
S42.4 Fracture of lower end of humerus	0.823	0.177	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.818	0.182	0.000
I44.1 Atrioventricular block, second degree	0.817	0.183	0.000
# Top node	0.816	0.184	0.000
I21 Acute myocardial infarction	0.813	0.187	0.000
Chapter V Mental and behavioural disorders	0.812	0.188	0.000
S42.2 Fracture of upper end of humerus	0.811	0.188	0.000
T51 Toxic effect of alcohol	0.806	0.194	0.000
I45 Other conduction disorders	0.805	0.195	0.000
F30-F39 Mood [affective] disorders	0.805	0.195	0.000
S10-S19 Injuries to the neck	0.804	0.196	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.798	0.202	0.000
T36 Poisoning by systemic antibiotics	0.798	0.202	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.788	0.212	0.000
S02.4 Fracture of malar and maxillary bones	0.788	0.212	0.000
S79 Other and unspecified injuries of hip and thigh	0.783	0.217	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.782	0.218	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.781	0.218	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.781	0.219	0.000
T78.4 Allergy, unspecified	0.778	0.222	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.776	0.224	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.772	0.228	0.000
O20 Haemorrhage in early pregnancy	0.000	0.228	0.771
O36 Maternal care for other known or suspected foetal problems	0.000	0.234	0.766
T50.9 Other and unspecified drugs, medicaments and biological substances	0.765	0.235	0.000
S90-S99 Injuries to the ankle and foot	0.764	0.236	0.000
I60-I69 Cerebrovascular diseases	0.764	0.236	0.000
I67 Other cerebrovascular diseases	0.764	0.236	0.000
F33 Recurrent depressive disorder	0.761	0.239	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.760	0.240	0.000
S02.60 Fracture of mandible (closed)	0.759	0.241	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.757	0.243	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.000	0.243	0.757
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.756	0.244	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.753	0.247	0.000
O47 False labour	0.000	0.247	0.753
S01 Open wound of head	0.751	0.249	0.000
I21.9 Acute myocardial infarction, unspecified	0.750	0.250	0.000
D50-D53 Nutritional anaemias	0.748	0.252	0.000
I49.5 Sick sinus syndrome	0.748	0.252	0.000
T81 Complications of procedures, not elsewhere classified	0.747	0.253	0.000
I25.1 Atherosclerotic heart disease	0.746	0.254	0.000
F32 Depressive episode	0.744	0.256	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.000	0.258	0.742
T51.0 Ethanol	0.742	0.258	0.000
S42.1 Fracture of scapula	0.741	0.259	0.000
S02.0 Fracture of vault of skull	0.739	0.261	0.000
O36.8 Maternal care for other specified foetal problems	0.000	0.264	0.736
S00.1 Contusion of eyelid and periocular area	0.736	0.264	0.000
S71.1 Open wound of thigh	0.733	0.267	0.000
S05.1 Contusion of eyeball and orbital tissues	0.732	0.268	0.000
S02.8 Fractures of other skull and facial bones	0.731	0.269	0.000
T42.4 Benzodiazepines	0.730	0.270	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.001	0.270	0.729
T40.2 Other opioids	0.730	0.270	0.000
S42.40 Fracture of lower end of humerus (closed)	0.728	0.272	0.000
T42.1 Iminostilbenes	0.728	0.272	0.000
O72.1 Other immediate postpartum haemorrhage	0.000	0.273	0.727
I49.9 Cardiac arrhythmia, unspecified	0.726	0.274	0.000
O66 Other obstructed labour	0.000	0.275	0.725
I47 Paroxysmal tachycardia	0.725	0.275	0.000
D50 Iron deficiency anaemia	0.723	0.277	0.000
I67.9 Cerebrovascular disease, unspecified	0.722	0.278	0.000
I49.0 Ventricular fibrillation and flutter	0.720	0.280	0.000
S06.2 Diffuse brain injury	0.719	0.281	0.000
O42 Premature rupture of membranes	0.000	0.281	0.719
O20.0 Threatened abortion	0.000	0.282	0.718
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.717	0.283	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.717	0.283	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.717	0.283	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.717	0.283	0.000
T33-T35 Frostbite	0.717	0.283	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283	0.000
T00-T07 Injuries involving multiple body regions	0.717	0.283	0.000
T43.9 Psychotropic drug, unspecified	0.716	0.284	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.716	0.284	0.000
T43.6 Psychostimulants with abuse potential	0.716	0.284	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.716	0.284	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.716	0.284	0.000
S41 Open wound of shoulder and upper arm	0.715	0.285	0.000
I45.6 Preexcitation syndrome	0.713	0.287	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.713	0.287	0.000
S02.3 Fracture of orbital floor	0.712	0.288	0.000
I25.2 Old myocardial infarction	0.712	0.288	0.000
I24 Other acute ischaemic heart diseases	0.710	0.290	0.000
S08 Traumatic amputation of part of head	0.709	0.291	0.000
S07 Crushing injury of head	0.709	0.291	0.000
S04 Injury of cranial nerves	0.709	0.291	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.709	0.291	0.000
S42.20 Fracture of upper end of humerus (closed)	0.708	0.292	0.000
S00.3 Superficial injury of nose	0.708	0.292	0.000
I42 Cardiomyopathy	0.708	0.292	0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.707	0.293	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.707	0.293	0.000
T39.4 Antirheumatics, not elsewhere classified	0.707	0.293	0.000
T39.2 Pyrazolone derivatives	0.707	0.293	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.707	0.293	0.000
I21.4 Acute subendocardial myocardial infarction	0.707	0.293	0.000
D50.8 Other iron deficiency anaemias	0.706	0.294	0.000
T79-T79 Certain early complications of trauma	0.705	0.295	0.000
O32.1 Maternal care for breech presentation	0.000	0.295	0.705
O68 Labour and delivery complicated by foetal stress [distress]	0.000	0.296	0.704
I22 Subsequent myocardial infarction	0.704	0.296	0.000
I44.3 Other and unspecified atrioventricular block	0.703	0.297	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.000	0.297	0.703
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.701	0.299	0.000
I67.8 Other specified cerebrovascular diseases	0.700	0.300	0.000
I44.2 Atrioventricular block, complete	0.697	0.303	0.000
I05-I09 Chronic rheumatic heart diseases	0.696	0.304	0.000
S48 Traumatic amputation of shoulder and upper arm	0.696	0.304	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.696	0.304	0.000
S44 Injury of nerves at shoulder and upper arm level	0.696	0.304	0.000
S47 Crushing injury of shoulder and upper arm	0.696	0.304	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.695	0.305	0.000
I45.9 Conduction disorder, unspecified	0.695	0.305	0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.693	0.307	0.000
S00.9 Superficial injury of head, part unspecified	0.692	0.308	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.692	0.308	0.000
S78 Traumatic amputation of hip and thigh	0.689	0.310	0.000
S77 Crushing injury of hip and thigh	0.689	0.310	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.689	0.310	0.000
S75 Injury of blood vessels at hip and thigh level	0.689	0.310	0.000
S74 Injury of nerves at hip and thigh level	0.689	0.310	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.689	0.310	0.000
T78.3 Angioneurotic oedema	0.689	0.311	0.000
O80-O84 Delivery	0.001	0.311	0.688
O30 Multiple gestation	0.000	0.312	0.688
F32.2 Severe depressive episode without psychotic symptoms	0.688	0.312	0.000
I67.2 Cerebral atherosclerosis	0.685	0.315	0.000
S42.9 Fracture of shoulder girdle, part unspecified	0.685	0.315	0.000
S42.8 Fracture of other parts of shoulder and upper arm	0.685	0.315	0.000
S42.7 Multiple fractures of clavicle, scapula and humerus	0.685	0.315	0.000
I45.2 Bifascicular block	0.685	0.315	0.000
S06.3 Focal brain injury	0.684	0.316	0.000
T23 Burn and corrosion of wrist and hand	0.683	0.317	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.683	0.317	0.000
O73 Retained placenta and membranes, without haemorrhage	0.000	0.318	0.682
D51 Vitamin B12 deficiency anaemia	0.681	0.319	0.000
O40 Polyhydramnios	0.000	0.320	0.680
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.001	0.320	0.679
S05.8 Other injuries of eye and orbit	0.678	0.322	0.000
S42.3 Fracture of shaft of humerus	0.678	0.322	0.000
O43 Placental disorders	0.000	0.322	0.678
F33.9 Recurrent depressive disorder, unspecified	0.676	0.324	0.000
I49.1 Atrial premature depolarisation	0.675	0.325	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.675	0.325	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.669	0.330	0.000
S02.7 Multiple fractures involving skull and facial bones	0.669	0.330	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.669	0.331	0.000
S02.1 Fracture of base of skull	0.667	0.333	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.663	0.337	0.000
I51 Complications and ill-defined descriptions of heart disease	0.663	0.337	0.000
Chapter XX External causes of morbidity and mortality	0.662	0.338	0.000
I49.8 Other specified cardiac arrhythmias	0.662	0.338	0.000
F30 Manic episode	0.661	0.339	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.661	0.339	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.661	0.339	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.661	0.339	0.000
T42.3 Barbiturates	0.661	0.339	0.000
T42.2 Succinimides and oxazolidinediones	0.661	0.339	0.000
T42.0 Hydantoin derivatives	0.661	0.339	0.000
S22.3 Fracture of rib	0.660	0.340	0.000
I30 Acute pericarditis	0.658	0.342	0.000
S00.5 Superficial injury of lip and oral cavity	0.658	0.342	0.000
S02.5 Fracture of tooth	0.658	0.342	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.657	0.343	0.000
S70.8 Other superficial injuries of hip and thigh	0.657	0.343	0.000
S70.7 Multiple superficial injuries of hip and thigh	0.657	0.343	0.000
S70.1 Contusion of thigh	0.657	0.343	0.000
S79.9 Unspecified injury of hip and thigh	0.655	0.345	0.000
T21 Burn and corrosion of trunk	0.655	0.345	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.655	0.345	0.000
I67.1 Cerebral aneurysm, nonruptured	0.655	0.345	0.000
T45.0 Antiallergic and antiemetic drugs	0.654	0.346	0.000
T36.0 Penicillins	0.653	0.346	0.000
S70.0 Contusion of hip	0.652	0.348	0.000
T75 Effects of other external causes	0.652	0.348	0.000
T74 Maltreatment syndromes	0.652	0.348	0.000
T73 Effects of other deprivation	0.652	0.348	0.000
T70 Effects of air pressure and water pressure	0.652	0.348	0.000
T69 Other effects of reduced temperature	0.652	0.348	0.000
T67 Effects of heat and light	0.652	0.348	0.000
T71 Asphyxiation	0.652	0.348	0.000
T66 Unspecified effects of radiation	0.652	0.348	0.000
T78.2 Anaphylactic shock, unspecified	0.649	0.351	0.000
I45.3 Trifascicular block	0.648	0.352	0.000
S42.01 Fracture of clavicle (open)	0.648	0.352	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.648	0.352	0.000
O48 Prolonged pregnancy	0.000	0.353	0.647
O44 Placenta praevia	0.000	0.353	0.647
S12 Fracture of neck	0.647	0.353	0.000
S60-S69 Injuries to the wrist and hand	0.647	0.353	0.000
O61 Failed induction of labour	0.000	0.354	0.646
F99-F99 Unspecified mental disorder	0.646	0.354	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.646	0.354	0.000
I37 Pulmonary valve disorders	0.646	0.354	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.645	0.355	0.000
I25.5 Ischaemic cardiomyopathy	0.644	0.356	0.000
S00.0 Superficial injury of scalp	0.642	0.358	0.000
S20 Superficial injury of thorax	0.641	0.359	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.641	0.359	0.000
T63 Toxic effect of contact with venomous animals	0.640	0.360	0.000
T81.4 Infection following a procedure, not elsewhere classified	0.640	0.360	0.000
S22.1 Multiple fractures of thoracic spine	0.639	0.361	0.000
O74 Complications of anaesthesia during labour and delivery	0.000	0.362	0.638
O71 Other obstetric trauma	0.000	0.362	0.638
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.000	0.362	0.638
O65 Obstructed labour due to maternal pelvic abnormality	0.000	0.362	0.638
O60 Preterm delivery	0.000	0.362	0.638
T15-T19 Effects of foreign body entering through natural orifice	0.638	0.362	0.000
O47.9 False labour, unspecified	0.000	0.362	0.637
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.636	0.364	0.000
T65 Toxic effect of other and unspecified substances	0.634	0.365	0.000
T62 Toxic effect of other noxious substances eaten as food	0.634	0.365	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.634	0.365	0.000
T60 Toxic effect of pesticides	0.634	0.365	0.000
T57 Toxic effect of other inorganic substances	0.634	0.365	0.000
T56 Toxic effect of metals	0.634	0.365	0.000
T54 Toxic effect of corrosive substances	0.634	0.365	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.634	0.365	0.000
T52 Toxic effect of organic solvents	0.634	0.365	0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.634	0.365	0.000
T58 Toxic effect of carbon monoxide	0.634	0.365	0.000
T55 Toxic effect of soaps and detergents	0.634	0.365	0.000
O72.0 Third-stage haemorrhage	0.000	0.366	0.634
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.633	0.367	0.000
F60-F69 Disorders of adult personality and behaviour	0.633	0.367	0.000
O29 Complications of anaesthesia during pregnancy	0.000	0.367	0.632
O22 Venous complications in pregnancy	0.000	0.367	0.632
O25 Malnutrition in pregnancy	0.000	0.367	0.632
F34 Persistent mood [affective] disorders	0.632	0.368	0.000
I44.0 Atrioventricular block, first degree	0.632	0.368	0.000
I05 Rheumatic mitral valve diseases	0.632	0.368	0.000
S50-S59 Injuries to the elbow and forearm	0.631	0.369	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.000	0.371	0.629
O45 Premature separation of placenta [abruptio placentae]	0.000	0.371	0.629
O33 Maternal care for known or suspected disproportion	0.000	0.371	0.629
O31 Complications specific to multiple gestation	0.000	0.371	0.629
O70.9 Perineal laceration during delivery, unspecified	0.000	0.372	0.628
O69 Labour and delivery complicated by umbilical cord complications	0.000	0.372	0.628
S05.9 Injury of eye and orbit, part unspecified	0.627	0.373	0.000
S05.7 Avulsion of eye	0.627	0.373	0.000
S05.6 Penetrating wound of eyeball without foreign body	0.627	0.373	0.000
S05.5 Penetrating wound of eyeball with foreign body	0.627	0.373	0.000
S05.4 Penetrating wound of orbit with or without foreign body	0.627	0.373	0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.627	0.373	0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.627	0.373	0.000
O70.3 Fourth degree perineal laceration during delivery	0.000	0.374	0.626
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.625	0.374	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.000	0.375	0.625
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.625	0.375	0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.000	0.375	0.624
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.000	0.375	0.624
O26.5 Maternal hypotension syndrome	0.000	0.375	0.624
O26.4 Herpes gestationis	0.000	0.375	0.624
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.000	0.375	0.624
O26.2 Pregnancy care of habitual aborter	0.000	0.375	0.624
O26.1 Low weight gain in pregnancy	0.000	0.375	0.624
O26.0 Excessive weight gain in pregnancy	0.000	0.375	0.624
T47.1 Other antacids and anti-gastric-secretion drugs	0.623	0.376	0.000
I36 Nonrheumatic tricuspid valve disorders	0.623	0.377	0.000
O63 Long labour	0.000	0.377	0.623
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.623	0.377	0.000
S26 Injury of heart	0.623	0.377	0.000
S25 Injury of blood vessels of thorax	0.623	0.377	0.000
S24 Injury of nerves and spinal cord at thorax level	0.623	0.377	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.623	0.377	0.000
S21 Open wound of thorax	0.623	0.377	0.000
I42.2 Other hypertrophic cardiomyopathy	0.623	0.377	0.000
S27 Injury of other and unspecified intrathoracic organs	0.623	0.377	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.622	0.378	0.000
F32.3 Severe depressive episode with psychotic symptoms	0.621	0.379	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.620	0.380	0.000
T59 Toxic effect of other gases, fumes and vapours	0.619	0.381	0.000
T50.8 Diagnostic agents	0.619	0.381	0.000
T50.7 Analeptics and opioid receptor antagonists	0.619	0.381	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.619	0.381	0.000
T50.5 Appetite depressants	0.619	0.381	0.000
T50.4 Drugs affecting uric acid metabolism	0.619	0.381	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.619	0.381	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.619	0.381	0.000
T50.1 Loop [high-ceiling] diuretics	0.619	0.381	0.000
T50.0 Mineralocorticoids and their antagonists	0.619	0.381	0.000
S06.9 Intracranial injury, unspecified	0.619	0.381	0.000
S06.7 Intracranial injury with prolonged coma	0.619	0.381	0.000
S06.4 Epidural haemorrhage	0.619	0.381	0.000
S06.1 Traumatic cerebral oedema	0.619	0.381	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.617	0.383	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.000	0.384	0.616
T40.6 Other and unspecified narcotics	0.615	0.384	0.000
S22.5 Flail chest	0.615	0.384	0.000
T14 Injury of unspecified body region	0.615	0.385	0.000
O28 Abnormal findings on antenatal screening of mother	0.001	0.385	0.614
T78.9 Adverse effect, unspecified	0.614	0.386	0.000
T78.8 Other adverse effects, not elsewhere classified	0.614	0.386	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.614	0.386	0.000
O21 Excessive vomiting in pregnancy	0.000	0.386	0.613
S29 Other and unspecified injuries of thorax	0.613	0.386	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.387	0.613
S01.1 Open wound of eyelid and periocular area	0.613	0.387	0.000
Chapter XXII Codes for special purposes	0.612	0.388	0.000
F32.8 Other depressive episodes	0.612	0.388	0.000
T25 Burn and corrosion of ankle and foot	0.611	0.389	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.611	0.389	0.000
T20 Burn and corrosion of head and neck	0.611	0.389	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.611	0.389	0.000
I52 Other heart disorders in diseases classified elsewhere	0.609	0.391	0.000
I48 Atrial fibrillation and flutter	0.609	0.391	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.609	0.391	0.000
I41 Myocarditis in diseases classified elsewhere	0.609	0.391	0.000
I40 Acute myocarditis	0.609	0.391	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.609	0.391	0.000
I32 Pericarditis in diseases classified elsewhere	0.609	0.391	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.608	0.392	0.000
S19 Other and unspecified injuries of neck	0.608	0.392	0.000
F39 Unspecified mood [affective] disorder	0.608	0.392	0.000
T87 Complications peculiar to reattachment and amputation	0.607	0.393	0.000
I00-I02 Acute rheumatic fever	0.607	0.393	0.000
S06.8 Other intracranial injuries	0.606	0.394	0.000
O85-O92 Complications predominantly related to the puerperium	0.001	0.394	0.604
I23 Certain current complications following acute myocardial infarction	0.605	0.395	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.605	0.395	0.000
T51.9 Alcohol, unspecified	0.604	0.396	0.000
S00.4 Superficial injury of ear	0.603	0.397	0.000
I45.5 Other specified heart block	0.603	0.397	0.000
I44.6 Other and unspecified fascicular block	0.602	0.398	0.000
I44.5 Left posterior fascicular block	0.602	0.398	0.000
I44.4 Left anterior fascicular block	0.602	0.398	0.000
S06.5 Traumatic subdural haemorrhage	0.602	0.398	0.000
I51.7 Cardiomegaly	0.602	0.398	0.000
S01.8 Open wound of other parts of head	0.601	0.399	0.000
O24 Diabetes mellitus in pregnancy	0.001	0.400	0.599
S01.2 Open wound of nose	0.599	0.401	0.000
S02.00 Fracture of vault of skull (closed)	0.599	0.401	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.599	0.401	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.598	0.402	0.000
T40.8 Lysergide [LSD]	0.598	0.402	0.000
T40.7 Cannabis (derivatives)	0.598	0.402	0.000
T40.5 Cocaine	0.598	0.402	0.000
T40.3 Methadone	0.598	0.402	0.000
T40.1 Heroin	0.598	0.402	0.000
T40.0 Opium	0.598	0.402	0.000
I49.2 Junctional premature depolarisation	0.598	0.402	0.000
S49.9 Unspecified injury of shoulder and upper arm	0.598	0.402	0.000
S02.61 Fracture of mandible (open)	0.597	0.403	0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.000	0.404	0.596
I25.0 Atherosclerotic cardiovascular disease, so described	0.596	0.404	0.000
O82 Single delivery by Caesarean section	0.000	0.405	0.594
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.000	0.406	0.594
I44.7 Left bundle-branch block, unspecified	0.594	0.406	0.000
O23 Infections of genito-urinary tract in pregnancy	0.000	0.406	0.593
S71.8 Open wound of other and unspecified parts of pelvic girdle	0.594	0.406	0.000
S71.7 Multiple open wounds of of hip and thigh	0.594	0.406	0.000
S71.0 Open wound of hip	0.594	0.406	0.000
O72.3 Postpartum coagulation defects	0.000	0.406	0.594
S06.0 Concussion	0.593	0.407	0.000
I49.3 Ventricular premature depolarisation	0.593	0.407	0.000
T68 Hypothermia	0.592	0.408	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.592	0.408	0.000
I25.6 Silent myocardial ischaemia	0.590	0.410	0.000
I25.4 Coronary artery aneurysm	0.590	0.410	0.000
O64.1 Obstructed labour due to breech presentation	0.000	0.410	0.590
O42.9 Premature rupture of membranes, unspecified	0.000	0.410	0.590
S42.41 Fracture of lower end of humerus (open)	0.590	0.410	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.590	0.410	0.000
S42.10 Fracture of scapula (closed)	0.588	0.412	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.587	0.412	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.586	0.414	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.585	0.415	0.000
F80-F89 Disorders of psychological development	0.585	0.415	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.000	0.416	0.584
I45.8 Other specified conduction disorders	0.584	0.416	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.583	0.417	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.582	0.418	0.000
F70-F79 Mental retardation	0.582	0.418	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.000	0.418	0.582
S42.21 Fracture of upper end of humerus (open)	0.582	0.418	0.000
V10-V19 Pedal cyclist injured in transport accident	0.581	0.418	0.000
F43 Reaction to severe stress, and adjustment disorders	0.580	0.420	0.000
F50 Eating disorders	0.580	0.420	0.000
S22.30 Fracture of rib (closed)	0.579	0.421	0.000
S40 Superficial injury of shoulder and upper arm	0.579	0.421	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.579	0.421	0.000
V20-V29 Motorcycle rider injured in transport accident	0.578	0.422	0.000
F32.0 Mild depressive episode	0.578	0.422	0.000
T51.8 Other alcohols	0.578	0.422	0.000
T51.3 Fusel oil	0.578	0.422	0.000
T51.2 2-Propanol	0.578	0.422	0.000
T51.1 Methanol	0.578	0.422	0.000
I45.4 Nonspecific intraventricular block	0.577	0.422	0.000
I45.0 Right fascicular block	0.577	0.422	0.000
F38 Other mood [affective] disorders	0.577	0.423	0.000
S17 Crushing injury of neck	0.576	0.423	0.000
S15 Injury of blood vessels at neck level	0.576	0.423	0.000
S14 Injury of nerves and spinal cord at neck level	0.576	0.423	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.576	0.423	0.000
S11 Open wound of neck	0.576	0.423	0.000
S18 Traumatic amputation at neck level	0.576	0.423	0.000
S16 Injury of muscle and tendon at neck level	0.576	0.423	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.574	0.426	0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.000	0.427	0.573
T45.9 Primarily systemic and haematological agent, unspecified	0.572	0.428	0.000
T45.8 Other primarily systemic and haematological agents	0.572	0.428	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.572	0.428	0.000
T45.6 Fibrinolysis-affecting drugs	0.572	0.428	0.000
T45.5 Anticoagulants	0.572	0.428	0.000
T45.4 Iron and its compounds	0.572	0.428	0.000
T45.3 Enzymes, not elsewhere classified	0.572	0.428	0.000
T45.2 Vitamins, not elsewhere classified	0.572	0.428	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.572	0.428	0.000
T36.9 Systemic antibiotic, unspecified	0.572	0.428	0.000
T36.8 Other systemic antibiotics	0.572	0.428	0.000
T36.7 Antifungal antibiotics, systemically used	0.572	0.428	0.000
T36.6 Rifamycins	0.572	0.428	0.000
T36.5 Aminoglycosides	0.572	0.428	0.000
T36.4 Tetracyclines	0.572	0.428	0.000
T36.3 Macrolides	0.572	0.428	0.000
T36.2 Chloramphenicol group	0.572	0.428	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.572	0.428	0.000
O16 Unspecified maternal hypertension	0.000	0.429	0.571
D52 Folate deficiency anaemia	0.571	0.429	0.000
I22.8 Subsequent myocardial infarction of other sites	0.569	0.431	0.000
O41 Other disorders of amniotic fluid and membranes	0.000	0.431	0.568
S10 Superficial injury of neck	0.568	0.432	0.000
T81.8 Other complications of procedures, not elsewhere classified	0.568	0.432	0.000
S01.3 Open wound of ear	0.567	0.433	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.565	0.435	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.565	0.435	0.000
T46.7 Peripheral vasodilators	0.565	0.435	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.565	0.435	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.565	0.435	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.565	0.435	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.565	0.435	0.000
T46.1 Calcium-channel blockers	0.565	0.435	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.565	0.435	0.000
S64 Injury of nerves at wrist and hand level	0.565	0.435	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.565	0.435	0.000
S90 Superficial injury of ankle and foot	0.565	0.435	0.000
I49.4 Other and unspecified premature depolarisation	0.564	0.436	0.000
S79.8 Other specified injuries of hip and thigh	0.562	0.438	0.000
S79.7 Multiple injuries of hip and thigh	0.562	0.438	0.000
S02.2 Fracture of nasal bones	0.561	0.438	0.000
T38.9 Other and unspecified hormone antagonists	0.561	0.439	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.561	0.439	0.000
T38.7 Androgens and anabolic congeners	0.561	0.439	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.561	0.439	0.000
T38.5 Other oestrogens and progestogens	0.561	0.439	0.000
T38.4 Oral contraceptives	0.561	0.439	0.000
T38.2 Antithyroid drugs	0.561	0.439	0.000
T38.1 Thyroid hormones and substitutes	0.561	0.439	0.000
T38.0 Glucocorticoids and synthetic analogues	0.561	0.439	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations