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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs73164250
log Bayes Factor = 17.0593
Chromosome 12   position 84,624,334  (GRCh37) Explore rs73164250 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter XX External causes of morbidity and mortality
0.998 0.002 0.000
M20-M25 Other joint disorders
0.998 0.002 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.994 0.006 0.000
M23 Internal derangement of knee
0.988 0.012 0.000
Chapter VII Diseases of the eye and adnexa
0.986 0.014 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.984 0.016 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.983 0.017 0.000
Chapter VI Diseases of the nervous system
0.978 0.022 0.000
Chapter XI Diseases of the digestive system
0.977 0.023 0.000
Chapter I Certain infectious and parasitic diseases
0.977 0.023 0.000
Chapter V Mental and behavioural disorders
0.974 0.026 0.000
M15-M19 Arthrosis
0.969 0.031 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.965 0.035 0.000
K65-K67 Diseases of peritoneum
0.963 0.037 0.000
Chapter XIV Diseases of the genitourinary system
0.961 0.039 0.000
M17 Gonarthrosis [arthrosis of knee]
0.958 0.042 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.955 0.045 0.000
E10-E14 Diabetes mellitus
0.954 0.046 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.953 0.047 0.000
S00-S09 Injuries to the head
0.952 0.048 0.000
K66 Other disorders of peritoneum
0.949 0.051 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.949 0.051 0.000
N17-N19 Renal failure
0.949 0.051 0.000
A30-A49 Other bacterial diseases
0.947 0.053 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.946 0.054 0.000
M17.9 Gonarthrosis, unspecified
0.943 0.057 0.000
Chapter IX Diseases of the circulatory system
0.941 0.059 0.000
K66.0 Peritoneal adhesions
0.936 0.064 0.000
K70-K77 Diseases of liver
0.934 0.066 0.000
C78.2 Secondary malignant neoplasm of pleura
0.933 0.067 0.000
N18 Chronic renal failure
0.932 0.068 0.000
Y43 Primarily systemic agents
0.932 0.068 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.931 0.069 0.000
C15-C26 Malignant neoplasms of digestive organs
0.930 0.070 0.000
K02 Dental caries
0.928 0.072 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.920 0.080 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.919 0.081 0.000
E11 Non-insulin-dependent diabetes mellitus
0.917 0.083 0.000
Chapter VIII Diseases of the ear and mastoid process
0.911 0.089 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.911 0.089 0.000
K02.9 Dental caries, unspecified
0.910 0.090 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.906 0.094 0.000
M23.3 Other meniscus derangements
0.903 0.097 0.000
M25 Other joint disorders, not elsewhere classified
0.900 0.100 0.000
N18.9 Chronic renal failure, unspecified
0.899 0.101 0.000
C79 Secondary malignant neoplasm of other sites
0.897 0.103 0.000
Y43.3 Other antineoplastic drugs
0.895 0.105 0.000
Y84.2 Radiological procedure and radiotherapy
0.894 0.106 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.893 0.107 0.000
A41 Other septicaemia
0.892 0.108 0.000
E70-E90 Metabolic disorders
0.886 0.114 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.886 0.114 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.885 0.115 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.884 0.116 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.883 0.117 0.000
F10.2 Dependence syndrome
0.879 0.121 0.000
C18 Malignant neoplasm of colon
0.878 0.122 0.000
M65-M68 Disorders of synovium and tendon
0.875 0.125 0.000
S02 Fracture of skull and facial bones
0.874 0.126 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.871 0.129 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.869 0.131 0.000
C78.0 Secondary malignant neoplasm of lung
0.867 0.133 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.864 0.136 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.864 0.136 0.000
E65-E68 Obesity and other hyperalimentation
0.864 0.136 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.863 0.137 0.000
H43-H45 Disorders of vitreous body and globe
0.861 0.139 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.858 0.142 0.000
S80-S89 Injuries to the knee and lower leg
0.856 0.144 0.000
M45-M49 Spondylopathies
0.854 0.146 0.000
K70 Alcoholic liver disease
0.852 0.148 0.000
C78.7 Secondary malignant neoplasm of liver
0.852 0.148 0.000
S01 Open wound of head
0.848 0.152 0.000
E11.3 With ophthalmic complications
0.847 0.153 0.000
M23.4 Loose body in knee
0.843 0.157 0.000
N10-N16 Renal tubulo-interstitial diseases
0.842 0.158 0.000
A49 Bacterial infection of unspecified site
0.840 0.159 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.840 0.160 0.000
M18 Arthrosis of first carpometacarpal joint
0.839 0.161 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.838 0.162 0.000
C77.0 Lymph nodes of head, face and neck
0.836 0.164 0.000
K14 Diseases of tongue
0.834 0.166 0.000
C77.8 Lymph nodes of multiple regions
0.833 0.167 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.830 0.170 0.000
Y42.7 Androgens and anabolic congeners
0.830 0.170 0.000
S40-S49 Injuries to the shoulder and upper arm
0.829 0.171 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.829 0.171 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.827 0.173 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.822 0.178 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.820 0.180 0.000
S90-S99 Injuries to the ankle and foot
0.819 0.181 0.000
H40-H42 Glaucoma
0.817 0.183 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.817 0.183 0.000
H10-H13 Disorders of conjunctiva
0.816 0.184 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.815 0.185 0.000
H55-H59 Other disorders of eye and adnexa
0.812 0.188 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.810 0.190 0.000
G20-G26 Extrapyramidal and movement disorders
0.810 0.190 0.000
C77.2 Intra-abdominal lymph nodes
0.808 0.192 0.000
H30-H36 Disorders of choroid and retina
0.808 0.192 0.000
C16 Malignant neoplasm of stomach
0.807 0.193 0.000
S20-S29 Injuries to the thorax
0.806 0.194 0.000
N30-N39 Other diseases of urinary system
0.805 0.195 0.000
I20-I25 Ischaemic heart diseases
0.804 0.196 0.000
C50-C50 Malignant neoplasm of breast
0.803 0.197 0.000
Y95 Nosocomial condition
0.802 0.198 0.000
G90-G99 Other disorders of the nervous system
0.801 0.199 0.000
H65-H75 Diseases of middle ear and mastoid
0.800 0.200 0.000
G30-G32 Other degenerative diseases of the nervous system
0.800 0.200 0.000
C77.9 Lymph node, unspecified
0.800 0.200 0.000
N18.5 Chronic kidney disease, stage 5
0.799 0.201 0.000
Y84.1 Kidney dialysis
0.798 0.202 0.000
I77 Other disorders of arteries and arterioles
0.797 0.203 0.000
K07 Dentofacial anomalies [including malocclusion]
0.797 0.203 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.796 0.204 0.000
G62 Other polyneuropathies
0.796 0.204 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.795 0.205 0.000
M80-M85 Disorders of bone density and structure
0.793 0.207 0.000
C64-C68 Malignant neoplasms of urinary tract
0.787 0.213 0.000
T86 Failure and rejection of transplanted organs and tissues
0.786 0.214 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.786 0.214 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.785 0.215 0.000
G40-G47 Episodic and paroxysmal disorders
0.785 0.215 0.000
S06 Intracranial injury
0.785 0.215 0.000
V40-V49 Car occupant injured in transport accident
0.783 0.217 0.000
E20-E35 Disorders of other endocrine glands
0.783 0.217 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.782 0.218 0.000
C77.4 Inguinal and lower limb lymph nodes
0.782 0.218 0.000
M40-M43 Deforming dorsopathies
0.782 0.218 0.000
E11.5 With peripheral circulatory complications
0.782 0.218 0.000
E11.4 With neurological complications
0.781 0.219 0.000
Chapter XXII Codes for special purposes
0.781 0.219 0.000
M17.1 Other primary gonarthrosis
0.780 0.220 0.000
M35 Other systemic involvement of connective tissue
0.780 0.220 0.000
E66 Obesity
0.779 0.221 0.000
N19 Unspecified renal failure
0.778 0.222 0.000
M86-M90 Other osteopathies
0.777 0.223 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.777 0.223 0.000
E11.2 With renal complications
0.777 0.223 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.776 0.224 0.000
N18.0 End-stage renal disease
0.776 0.224 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.776 0.224 0.000
H49 Paralytic strabismus
0.775 0.225 0.000
T66-T78 Other and unspecified effects of external causes
0.774 0.226 0.000
M25.5 Pain in joint
0.772 0.228 0.000
B95-B98 Bacterial, viral and other infectious agents
0.772 0.228 0.000
K65 Peritonitis
0.771 0.229 0.000
C80 Malignant neoplasm without specification of site
0.768 0.231 0.000
K70.9 Alcoholic liver disease, unspecified
0.768 0.232 0.000
H43 Disorders of vitreous body
0.766 0.234 0.000
M25.7 Osteophyte
0.766 0.234 0.000
K76 Other diseases of liver
0.766 0.234 0.000
M91-M94 Chondropathies
0.765 0.235 0.000
K74 Fibrosis and cirrhosis of liver
0.765 0.235 0.000
G63.2 Diabetic polyneuropathy
0.764 0.236 0.000
B35-B49 Mycoses
0.763 0.237 0.000
M20 Acquired deformities of fingers and toes
0.763 0.237 0.000
N00-N08 Glomerular diseases
0.761 0.238 0.000
E87.2 Acidosis
0.759 0.241 0.000
W20-W49 Exposure to inanimate mechanical forces
0.759 0.241 0.000
C18.0 Caecum
0.758 0.242 0.000
M21 Other acquired deformities of limbs
0.757 0.243 0.000
E13 Other specified diabetes mellitus
0.757 0.243 0.000
F10.3 Withdrawal state
0.756 0.244 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.756 0.244 0.000
C60-C63 Malignant neoplasms of male genital organs
0.755 0.245 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.755 0.245 0.000
M17.3 Other posttraumatic gonarthrosis
0.755 0.245 0.000
Y40 Systemic antibiotics
0.755 0.245 0.000
S70-S79 Injuries to the hip and thigh
0.753 0.247 0.000
A49.8 Other bacterial infections of unspecified site
0.753 0.247 0.000
M24 Other specific joint derangements
0.752 0.248 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.750 0.249 0.000
E87.6 Hypokalaemia
0.750 0.250 0.000
Y52 Agents primarily affecting the cardiovascular system
0.750 0.250 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.748 0.252 0.000
M22 Disorders of patella
0.748 0.252 0.000
T92 Sequelae of injuries of upper limb
0.747 0.253 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.746 0.253 0.000
K66.8 Other specified disorders of peritoneum
0.744 0.256 0.000
T79-T79 Certain early complications of trauma
0.744 0.256 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.743 0.257 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.743 0.257 0.000
H52 Disorders of refraction and accommodation
0.743 0.257 0.000
E10 Insulin-dependent diabetes mellitus
0.742 0.258 0.000
A80-A89 Viral infections of the central nervous system
0.741 0.259 0.000
K10 Other diseases of jaws
0.740 0.260 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.740 0.260 0.000
M23.49 Loose body in knee-Unspec lig/men
0.739 0.261 0.000
M05-M14 Inflammatory polyarthropathies
0.738 0.262 0.000
K90-K93 Other diseases of the digestive system
0.738 0.262 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.737 0.263 0.000
K12 Stomatitis and related lesions
0.736 0.264 0.000
I24 Other acute ischaemic heart diseases
0.735 0.265 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.735 0.265 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.735 0.265 0.000
N17 Acute renal failure
0.735 0.265 0.000
C18.7 Sigmoid colon
0.734 0.266 0.000
M65 Synovitis and tenosynovitis
0.733 0.267 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.731 0.269 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.729 0.271 0.000
H60-H62 Diseases of external ear
0.729 0.271 0.000
N18.4 Chronic kidney disease, stage 4
0.729 0.271 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.728 0.272 0.000
I72 Other aneurysm
0.728 0.272 0.000
H50 Other strabismus
0.728 0.272 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.727 0.273 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.727 0.273 0.000
K09 Cysts of oral region, not elsewhere classified
0.727 0.273 0.000
S02.4 Fracture of malar and maxillary bones
0.725 0.275 0.000
G47 Sleep disorders
0.724 0.276 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.724 0.276 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.724 0.276 0.000
C92 Myeloid leukaemia
0.724 0.276 0.000
V20-V29 Motorcycle rider injured in transport accident
0.723 0.277 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.721 0.279 0.000
H90-H95 Other disorders of ear
0.721 0.279 0.000
C16.0 Cardia
0.721 0.279 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.719 0.281 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.719 0.281 0.000
K14.0 Glossitis
0.718 0.282 0.000
M67 Other disorders of synovium and tendon
0.718 0.282 0.000
I95 Hypotension
0.718 0.282 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.717 0.283 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.717 0.283 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
S01.1 Open wound of eyelid and periocular area
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.283 0.000
S10-S19 Injuries to the neck
0.716 0.283 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.716 0.284 0.000
E66.9 Obesity, unspecified
0.716 0.284 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.715 0.285 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.715 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.285 0.000
Y10-Y34 Event of undetermined intent
0.715 0.285 0.000
Y00-Y09 Assault
0.715 0.285 0.000
X85-X99 Assault
0.715 0.285 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.715 0.285 0.000
X50-X57 Overexertion, travel and privation
0.715 0.285 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.715 0.285 0.000
X30-X39 Exposure to forces of nature
0.715 0.285 0.000
X20-X29 Contact with venomous animals and plants
0.715 0.285 0.000
X10-X19 Contact with heat and hot substances
0.715 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.285 0.000
W75-W84 Other accidental threats to breathing
0.715 0.285 0.000
W65-W74 Accidental drowning and submersion
0.715 0.285 0.000
W50-W64 Exposure to animate mechanical forces
0.715 0.285 0.000
V98-V99 Other and unspecified transport accidents
0.715 0.285 0.000
V95-V97 Air and space transport accidents
0.715 0.285 0.000
V90-V94 Water transport accidents
0.715 0.285 0.000
V80-V89 Other land transport accidents
0.715 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.285 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.715 0.285 0.000
M34 Systemic sclerosis
0.715 0.285 0.000
M33 Dermatopolymyositis
0.715 0.285 0.000
M32 Systemic lupus erythematosus
0.715 0.285 0.000
M30 Polyarteritis nodosa and related conditions
0.715 0.285 0.000
Q60-Q64 Congenital malformations of the urinary system
0.715 0.285 0.000
S60-S69 Injuries to the wrist and hand
0.714 0.286 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.714 0.286 0.000
H65 Nonsuppurative otitis media
0.713 0.287 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.713 0.287 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.713 0.287 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.713 0.287 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.713 0.287 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.713 0.287 0.000
S01.2 Open wound of nose
0.712 0.288 0.000
C67 Malignant neoplasm of bladder
0.712 0.288 0.000
M47 Spondylosis
0.711 0.289 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.711 0.289 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.709 0.291 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.708 0.292 0.000
M23.9 Internal derangement of knee, unspecified
0.708 0.292 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.708 0.292 0.000
M23.5 Chronic instability of knee
0.708 0.292 0.000
M23.1 Discoid meniscus (congenital)
0.708 0.292 0.000
M23.0 Cystic meniscus
0.708 0.292 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.707 0.293 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.707 0.293 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.706 0.294 0.000
B15-B19 Viral hepatitis
0.706 0.294 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.706 0.294 0.000
N25-N29 Other disorders of kidney and ureter
0.706 0.294 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.706 0.294 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.706 0.294 0.000
E40-E46 Malnutrition
0.705 0.294 0.000
V10-V19 Pedal cyclist injured in transport accident
0.705 0.295 0.000
Y59 Other and unspecified vaccines and biological substances
0.704 0.295 0.000
Y58 Bacterial vaccines
0.704 0.295 0.000
Y57 Other and unspecified drugs and medicaments
0.704 0.295 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.704 0.295 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.704 0.295 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.704 0.295 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.704 0.295 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.704 0.295 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.704 0.295 0.000
Y48 Anaesthetics and therapeutic gases
0.704 0.295 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.704 0.295 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.704 0.295 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.704 0.295 0.000
F99-F99 Unspecified mental disorder
0.704 0.295 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.704 0.296 0.000
N30 Cystitis
0.704 0.296 0.000
B25-B34 Other viral diseases
0.703 0.297 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.702 0.298 0.000
K35-K38 Diseases of appendix
0.702 0.298 0.000
S02.8 Fractures of other skull and facial bones
0.702 0.298 0.000
G70-G73 Diseases of myoneural junction and muscle
0.701 0.299 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.701 0.299 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.701 0.299 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.701 0.299 0.000
B99-B99 Other infectious diseases
0.700 0.299 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.700 0.299 0.000
B65-B83 Helminthiases
0.700 0.299 0.000
B50-B64 Protozoal diseases
0.700 0.299 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.700 0.299 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.700 0.299 0.000
A75-A79 Rickettsioses
0.700 0.299 0.000
A70-A74 Other diseases caused by chlamydiae
0.700 0.299 0.000
A65-A69 Other spirochaetal diseases
0.700 0.299 0.000
A20-A28 Certain zoonotic bacterial diseases
0.700 0.299 0.000
A15-A19 Tuberculosis
0.700 0.299 0.000
Y44 Agents primarily affecting blood constituents
0.700 0.300 0.000
E87.3 Alkalosis
0.700 0.300 0.000
T90 Sequelae of injuries of head
0.698 0.302 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.698 0.302 0.000
F80-F89 Disorders of psychological development
0.698 0.302 0.000
F70-F79 Mental retardation
0.698 0.302 0.000
F60-F69 Disorders of adult personality and behaviour
0.698 0.302 0.000
S81 Open wound of lower leg
0.698 0.302 0.000
S02.0 Fracture of vault of skull
0.698 0.302 0.000
S01.5 Open wound of lip and oral cavity
0.697 0.303 0.000
G47.3 Sleep apnoea
0.697 0.303 0.000
H53-H54 Visual disturbances and blindness
0.696 0.304 0.000
H40 Glaucoma
0.696 0.304 0.000
M15 Polyarthrosis
0.695 0.305 0.000
H36 Retinal disorders in diseases classified elsewhere
0.694 0.306 0.000
C18.3 Hepatic flexure
0.693 0.307 0.000
G25 Other extrapyramidal and movement disorders
0.693 0.307 0.000
M20.4 Other hammer toe(s) (acquired)
0.693 0.307 0.000
H43.1 Vitreous haemorrhage
0.693 0.307 0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere
0.691 0.309 0.000
S02.1 Fracture of base of skull
0.690 0.310 0.000
K07.6 Temporomandibular joint disorders
0.690 0.310 0.000
F17.2 Dependence syndrome
0.690 0.310 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.689 0.311 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.689 0.311 0.000
X60-X84 Intentional self-harm
0.688 0.311 0.000
I74 Arterial embolism and thrombosis
0.687 0.313 0.000
M17.5 Other secondary gonarthrosis
0.687 0.313 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.687 0.313 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.687 0.313 0.000
E14 Unspecified diabetes mellitus
0.687 0.313 0.000
E87.0 Hyperosmolality and hypernatraemia
0.686 0.314 0.000
A41.8 Other specified septicaemia
0.686 0.314 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.686 0.314 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.684 0.315 0.000
E12 Malnutrition-related diabetes mellitus
0.684 0.316 0.000
K70.3 Alcoholic cirrhosis of liver
0.684 0.316 0.000
K03 Other diseases of hard tissues of teeth
0.683 0.317 0.000
K00 Disorders of tooth development and eruption
0.683 0.317 0.000
L40-L45 Papulosquamous disorders
0.683 0.317 0.000
S08 Traumatic amputation of part of head
0.682 0.318 0.000
S07 Crushing injury of head
0.682 0.318 0.000
S05 Injury of eye and orbit
0.682 0.318 0.000
S04 Injury of cranial nerves
0.682 0.318 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.682 0.318 0.000
K75 Other inflammatory liver diseases
0.682 0.318 0.000
H49.2 Sixth [abducent] nerve palsy
0.682 0.318 0.000
C18.4 Transverse colon
0.682 0.318 0.000
G93 Other disorders of brain
0.681 0.318 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.681 0.318 0.000
M48 Other spondylopathies
0.681 0.319 0.000
K66.9 Disorder of peritoneum, unspecified
0.680 0.319 0.000
K66.1 Haemoperitoneum
0.680 0.319 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.680 0.320 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.680 0.320 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.680 0.320 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.680 0.320 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.680 0.320 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.680 0.320 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.680 0.320 0.000
F11 Mental and behavioural disorders due to use of opioids
0.680 0.320 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.680 0.320 0.000
F30-F39 Mood [affective] disorders
0.680 0.320 0.000
C18.2 Ascending colon
0.679 0.321 0.000
A48 Other bacterial diseases, not elsewhere classified
0.679 0.321 0.000
A44 Bartonellosis
0.679 0.321 0.000
A43 Nocardiosis
0.679 0.321 0.000
A42 Actinomycosis
0.679 0.321 0.000
A40 Streptococcal septicaemia
0.679 0.321 0.000
A39 Meningococcal infection
0.679 0.321 0.000
A37 Whooping cough
0.679 0.321 0.000
A36 Diphtheria
0.679 0.321 0.000
A32 Listeriosis
0.679 0.321 0.000
A31 Infection due to other mycobacteria
0.679 0.321 0.000
A30 Leprosy [Hansen's disease]
0.679 0.321 0.000
A46 Erysipelas
0.679 0.321 0.000
A38 Scarlet fever
0.679 0.321 0.000
A35 Other tetanus
0.679 0.321 0.000
A34 Obstetrical tetanus
0.679 0.321 0.000
A33 Tetanus neonatorum
0.679 0.321 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.679 0.321 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.677 0.322 0.000
C77.5 Intrapelvic lymph nodes
0.677 0.323 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.677 0.323 0.000
E87.5 Hyperkalaemia
0.677 0.323 0.000
N60-N64 Disorders of breast
0.677 0.323 0.000
E83 Disorders of mineral metabolism
0.677 0.323 0.000
N73 Other female pelvic inflammatory diseases
0.676 0.324 0.000
C77.1 Intrathoracic lymph nodes
0.675 0.325 0.000
N35 Urethral stricture
0.675 0.325 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.675 0.325 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.675 0.325 0.000
I00-I02 Acute rheumatic fever
0.674 0.325 0.000
M35.3 Polymyalgia rheumatica
0.674 0.325 0.000
K72 Hepatic failure, not elsewhere classified
0.674 0.326 0.000
I77.8 Other specified disorders of arteries and arterioles
0.672 0.328 0.000
K90 Intestinal malabsorption
0.671 0.329 0.000
C15 Malignant neoplasm of oesophagus
0.671 0.329 0.000
G62.8 Other specified polyneuropathies
0.671 0.329 0.000
M31 Other necrotising vasculopathies
0.670 0.330 0.000
G30 Alzheimer's disease
0.670 0.330 0.000
K77 Liver disorders in diseases classified elsewhere
0.669 0.330 0.000
K73 Chronic hepatitis, not elsewhere classified
0.669 0.330 0.000
K71 Toxic liver disease
0.669 0.330 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.669 0.330 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.668 0.331 0.000
S80 Superficial injury of lower leg
0.668 0.331 0.000
I24.8 Other forms of acute ischaemic heart disease
0.668 0.332 0.000
N18.8 Other chronic renal failure
0.668 0.332 0.000
N18.2 Chronic kidney disease, stage 2
0.668 0.332 0.000
N18.1 Chronic kidney disease, stage 1
0.668 0.332 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.668 0.332 0.000
Y43.9 Primarily systemic agent, unspecified
0.668 0.332 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.668 0.332 0.000
Y43.6 Enzymes, not elsewhere classified
0.668 0.332 0.000
Y43.5 Acidifying and alkalising agents
0.668 0.332 0.000
Y43.4 Immunosuppressive agents
0.668 0.332 0.000
Y43.2 Antineoplastic natural products
0.668 0.332 0.000
Y43.1 Antineoplastic antimetabolites
0.668 0.332 0.000
Y43.0 Antiallergic and antiemetic drugs
0.668 0.332 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.668 0.332 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.667 0.332 0.000
T87 Complications peculiar to reattachment and amputation
0.667 0.332 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.667 0.332 0.000
M17.0 Primary gonarthrosis, bilateral
0.667 0.332 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.667 0.333 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.667 0.333 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.667 0.333 0.000
C21 Malignant neoplasm of anus and anal canal
0.667 0.333 0.000
C17 Malignant neoplasm of small intestine
0.667 0.333 0.000
C23 Malignant neoplasm of gallbladder
0.667 0.333 0.000
K02.8 Other dental caries
0.665 0.335 0.000
K02.5 Caries with pulp exposure
0.665 0.335 0.000
K02.4 Odontoclasia
0.665 0.335 0.000
K02.3 Arrested dental caries
0.665 0.335 0.000
K02.2 Caries of cementum
0.665 0.335 0.000
K02.1 Caries of dentin
0.665 0.335 0.000
K02.0 Caries limited to enamel
0.665 0.335 0.000
I77.1 Stricture of artery
0.665 0.335 0.000
I83 Varicose veins of lower extremities
0.665 0.335 0.000
S92 Fracture of foot, except ankle
0.665 0.335 0.000
N10 Acute tubulo-interstitial nephritis
0.664 0.335 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.664 0.336 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.663 0.337 0.000
M25.51 Pain in joint (Shoulder region)
0.662 0.338 0.000
C50 Malignant neoplasm of breast
0.662 0.338 0.000
K14.8 Other diseases of tongue
0.662 0.338 0.000
K11 Diseases of salivary glands
0.661 0.339 0.000
F17.1 Harmful use
0.661 0.339 0.000
H55 Nystagmus and other irregular eye movements
0.661 0.339 0.000
H04 Disorders of lachrymal system
0.661 0.339 0.000
Y84.9 Medical procedure, unspecified
0.659 0.340 0.000
Y84.7 Blood-sampling
0.659 0.340 0.000
Y84.5 Insertion of gastric or duodenal sound
0.659 0.340 0.000
Y84.4 Aspiration of fluid
0.659 0.340 0.000
Y84.3 Shock therapy
0.659 0.340 0.000
Y84.0 Cardiac catheterisation
0.659 0.340 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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