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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs73173542
log Bayes Factor = 15.7101
Chromosome 5   position 87,810,867  (GRCh37) Explore rs73173542 on Ensembl!
Variant rs73173542 is part of Cluster X0044

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
J40-J47 Chronic lower respiratory diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
J44 Other chronic obstructive pulmonary disease
0.998 0.002 0.000
I30-I52 Other forms of heart disease
0.996 0.004 0.000
Chapter VI Diseases of the nervous system
0.996 0.004 0.000
Chapter XXI Factors influencing health status and contact with health services
0.995 0.005 0.000
I50 Heart failure
0.995 0.005 0.000
M05-M14 Inflammatory polyarthropathies
0.994 0.006 0.000
Chapter V Mental and behavioural disorders
0.990 0.010 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.990 0.010 0.000
I60-I69 Cerebrovascular diseases
0.988 0.012 0.000
M06 Other rheumatoid arthritis
0.986 0.014 0.000
Chapter XIV Diseases of the genitourinary system
0.985 0.015 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.983 0.017 0.000
M06.9 Rheumatoid arthritis, unspecified
0.979 0.021 0.000
I50.1 Left ventricular failure
0.978 0.022 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.976 0.024 0.000
N30-N39 Other diseases of urinary system
0.975 0.025 0.000
Chapter XI Diseases of the digestive system
0.974 0.026 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.973 0.027 0.000
G40-G47 Episodic and paroxysmal disorders
0.959 0.041 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.953 0.047 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.949 0.051 0.000
Chapter I Certain infectious and parasitic diseases
0.943 0.057 0.000
Z72 Problems related to lifestyle
0.943 0.057 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.942 0.058 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.936 0.064 0.000
Chapter II Neoplasms
0.933 0.067 0.000
M80-M85 Disorders of bone density and structure
0.932 0.068 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.930 0.070 0.000
I50.9 Heart failure, unspecified
0.929 0.071 0.000
Z03.8 Observation for other suspected diseases and conditions
0.928 0.072 0.000
N39 Other disorders of urinary system
0.926 0.074 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.925 0.075 0.000
K55-K64 Other diseases of intestines
0.923 0.077 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.921 0.079 0.000
J47 Bronchiectasis
0.921 0.079 0.000
S00-S09 Injuries to the head
0.920 0.080 0.000
I69 Sequelae of cerebrovascular disease
0.918 0.082 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.917 0.083 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.917 0.083 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.915 0.085 0.000
F41 Other anxiety disorders
0.914 0.086 0.000
S60-S69 Injuries to the wrist and hand
0.913 0.087 0.000
C44 Other malignant neoplasms of skin
0.911 0.089 0.000
C44.3 Skin of other and unspecified parts of face
0.908 0.092 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.907 0.093 0.000
I50.0 Congestive heart failure
0.905 0.095 0.000
N00-N08 Glomerular diseases
0.904 0.096 0.000
J09-J18 Influenza and pneumonia
0.904 0.096 0.000
K63 Other diseases of intestine
0.902 0.098 0.000
J95-J99 Other diseases of the respiratory system
0.901 0.099 0.000
Z72.0 Tobacco use
0.899 0.101 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.897 0.103 0.000
Z51 Other medical care
0.883 0.117 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.879 0.121 0.000
M81 Osteoporosis without pathological fracture
0.879 0.121 0.000
Z51.2 Other chemotherapy
0.878 0.122 0.000
G90-G99 Other disorders of the nervous system
0.877 0.123 0.000
M45-M49 Spondylopathies
0.875 0.125 0.000
M10 Gout
0.874 0.126 0.000
N39.4 Other specified urinary incontinence
0.870 0.130 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.867 0.133 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.867 0.133 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.866 0.134 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.866 0.134 0.000
J46 Status asthmaticus
0.860 0.140 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.859 0.141 0.000
I05-I09 Chronic rheumatic heart diseases
0.858 0.142 0.000
K63.8 Other specified diseases of intestine
0.854 0.146 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.852 0.148 0.000
F43 Reaction to severe stress, and adjustment disorders
0.851 0.149 0.000
I60 Subarachnoid haemorrhage
0.849 0.150 0.000
Z75 Problems related to medical facilities and other health care
0.848 0.152 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.844 0.156 0.000
K63.5 Polyp of colon
0.844 0.156 0.000
Chapter XX External causes of morbidity and mortality
0.844 0.156 0.000
N10-N16 Renal tubulo-interstitial diseases
0.842 0.158 0.000
M81.9 Osteoporosis, unspecified
0.841 0.159 0.000
I51 Complications and ill-defined descriptions of heart disease
0.840 0.160 0.000
F45 Somatoform disorders
0.839 0.161 0.000
F41.2 Mixed anxiety and depressive disorder
0.838 0.162 0.000
G40 Epilepsy
0.836 0.164 0.000
T90 Sequelae of injuries of head
0.834 0.166 0.000
K11 Diseases of salivary glands
0.834 0.166 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.831 0.169 0.000
R42 Dizziness and giddiness
0.829 0.171 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.827 0.173 0.000
S09 Other and unspecified injuries of head
0.826 0.174 0.000
J18 Pneumonia, organism unspecified
0.824 0.176 0.000
K35-K38 Diseases of appendix
0.824 0.176 0.000
M65-M68 Disorders of synovium and tendon
0.823 0.177 0.000
J90-J94 Other diseases of pleura
0.822 0.178 0.000
S62 Fracture at wrist and hand level
0.822 0.178 0.000
N30 Cystitis
0.818 0.182 0.000
F30-F39 Mood [affective] disorders
0.817 0.183 0.000
B95-B98 Bacterial, viral and other infectious agents
0.816 0.184 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.813 0.187 0.000
N31.8 Other neuromuscular dysfunction of bladder
0.812 0.188 0.000
G47 Sleep disorders
0.810 0.190 0.000
M70-M79 Other soft tissue disorders
0.808 0.192 0.000
K13 Other diseases of lip and oral mucosa
0.808 0.192 0.000
I67 Other cerebrovascular diseases
0.802 0.198 0.000
I61 Intracerebral haemorrhage
0.798 0.201 0.000
B25-B34 Other viral diseases
0.798 0.202 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.798 0.202 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.798 0.202 0.000
J18.9 Pneumonia, unspecified
0.797 0.203 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.795 0.205 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.792 0.208 0.000
R45 Symptoms and signs involving emotional state
0.792 0.208 0.000
J40 Bronchitis, not specified as acute or chronic
0.790 0.210 0.000
K50-K52 Noninfective enteritis and colitis
0.789 0.211 0.000
M10.9 Gout, unspecified
0.789 0.211 0.000
F60-F69 Disorders of adult personality and behaviour
0.787 0.213 0.000
N04 Nephrotic syndrome
0.787 0.213 0.000
K55 Vascular disorders of intestine
0.787 0.213 0.000
N39.3 Stress incontinence
0.786 0.214 0.000
R26 Abnormalities of gait and mobility
0.786 0.214 0.000
N32 Other disorders of bladder
0.785 0.215 0.000
K08 Other disorders of teeth and supporting structures
0.785 0.215 0.000
J30-J39 Other diseases of upper respiratory tract
0.783 0.217 0.000
N25-N29 Other disorders of kidney and ureter
0.781 0.219 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.781 0.219 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.781 0.219 0.000
N60-N64 Disorders of breast
0.781 0.219 0.000
J98 Other respiratory disorders
0.779 0.221 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.778 0.222 0.000
M05 Seropositive rheumatoid arthritis
0.776 0.223 0.000
K02 Dental caries
0.775 0.225 0.000
Z04 Examination and observation for other reasons
0.774 0.226 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.773 0.227 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.773 0.227 0.000
C44.1 Skin of eyelid, including canthus
0.773 0.227 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.772 0.228 0.000
Z72.1 Alcohol use
0.772 0.228 0.000
I35 Nonrheumatic aortic valve disorders
0.770 0.230 0.000
C15-C26 Malignant neoplasms of digestive organs
0.770 0.230 0.000
N02 Recurrent and persistent haematuria
0.769 0.231 0.000
M48 Other spondylopathies
0.769 0.231 0.000
C51-C58 Malignant neoplasms of female genital organs
0.768 0.232 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.767 0.233 0.000
J60-J70 Lung diseases due to external agents
0.767 0.233 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.767 0.233 0.000
S61 Open wound of wrist and hand
0.767 0.233 0.000
G62 Other polyneuropathies
0.766 0.234 0.000
F43.0 Acute stress reaction
0.763 0.237 0.000
G93 Other disorders of brain
0.760 0.240 0.000
I34 Nonrheumatic mitral valve disorders
0.759 0.241 0.000
S09.9 Unspecified injury of head
0.758 0.242 0.000
I27 Other pulmonary heart diseases
0.758 0.242 0.000
I62 Other nontraumatic intracranial haemorrhage
0.757 0.243 0.000
N13 Obstructive and reflux uropathy
0.757 0.243 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.757 0.243 0.000
Z43 Attention to artificial openings
0.756 0.243 0.000
Chapter XXII Codes for special purposes
0.756 0.244 0.000
S20-S29 Injuries to the thorax
0.755 0.245 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.755 0.245 0.000
K12 Stomatitis and related lesions
0.755 0.245 0.000
J90 Pleural effusion, not elsewhere classified
0.754 0.246 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.752 0.248 0.000
Z75.1 Person awaiting admission to adequate facility elsewhere
0.752 0.248 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.752 0.248 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.750 0.249 0.000
N20-N23 Urolithiasis
0.749 0.251 0.000
G41 Status epilepticus
0.749 0.251 0.000
G35 Multiple sclerosis
0.748 0.252 0.000
Z51.5 Palliative care
0.747 0.253 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.747 0.253 0.000
G81 Hemiplegia
0.745 0.255 0.000
S01 Open wound of head
0.745 0.255 0.000
Z03.3 Observation for suspected nervous system disorder
0.744 0.256 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.744 0.256 0.000
K70-K77 Diseases of liver
0.744 0.256 0.000
M06.0 Seronegative rheumatoid arthritis
0.743 0.257 0.000
M86-M90 Other osteopathies
0.742 0.257 0.000
F45.8 Other somatoform disorders
0.742 0.258 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.741 0.259 0.000
Z48 Other surgical follow-up care
0.741 0.259 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.736 0.264 0.000
J98.4 Other disorders of lung
0.735 0.265 0.000
M40-M43 Deforming dorsopathies
0.733 0.267 0.000
A80-A89 Viral infections of the central nervous system
0.733 0.267 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.733 0.267 0.000
I47 Paroxysmal tachycardia
0.733 0.267 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.731 0.269 0.000
M81.98 Osteoporosis, unspecified (Other)
0.730 0.270 0.000
K63.1 Perforation of intestine (nontraumatic)
0.729 0.271 0.000
K57 Diverticular disease of intestine
0.727 0.273 0.000
S62.6 Fracture of other finger
0.727 0.273 0.000
B15-B19 Viral hepatitis
0.726 0.274 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.726 0.274 0.000
F40 Phobic anxiety disorders
0.724 0.276 0.000
R50-R69 General symptoms and signs
0.724 0.276 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.723 0.277 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.723 0.277 0.000
Z71.1 Person with feared complaint in whom no diagnosis is made
0.719 0.281 0.000
S90-S99 Injuries to the ankle and foot
0.719 0.281 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
J41 Simple and mucopurulent chronic bronchitis
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
M91-M94 Chondropathies
0.716 0.284 0.000
M60-M63 Disorders of muscles
0.716 0.284 0.000
M00-M03 Infectious arthropathies
0.716 0.284 0.000
M79.8 Other specified soft tissue disorders
0.716 0.284 0.000
I52 Other heart disorders in diseases classified elsewhere
0.714 0.286 0.000
I48 Atrial fibrillation and flutter
0.714 0.286 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.714 0.286 0.000
I41 Myocarditis in diseases classified elsewhere
0.714 0.286 0.000
I40 Acute myocarditis
0.714 0.286 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.714 0.286 0.000
I37 Pulmonary valve disorders
0.714 0.286 0.000
I36 Nonrheumatic tricuspid valve disorders
0.714 0.286 0.000
I33 Acute and subacute endocarditis
0.714 0.286 0.000
I32 Pericarditis in diseases classified elsewhere
0.714 0.286 0.000
I30 Acute pericarditis
0.714 0.286 0.000
B35-B49 Mycoses
0.714 0.286 0.000
G70-G73 Diseases of myoneural junction and muscle
0.714 0.286 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.714 0.286 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.713 0.287 0.000
M14 Arthropathies in other diseases classified elsewhere
0.713 0.287 0.000
M12 Other specific arthropathies
0.713 0.287 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.713 0.287 0.000
M08 Juvenile arthritis
0.713 0.287 0.000
Z73 Problems related to life-management difficulty
0.713 0.287 0.000
W20-W49 Exposure to inanimate mechanical forces
0.710 0.290 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.710 0.290 0.000
J11 Influenza, virus not identified
0.710 0.290 0.000
F99-F99 Unspecified mental disorder
0.710 0.290 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.710 0.290 0.000
F80-F89 Disorders of psychological development
0.710 0.290 0.000
F70-F79 Mental retardation
0.710 0.290 0.000
T79-T79 Certain early complications of trauma
0.710 0.290 0.000
T33-T35 Frostbite
0.710 0.290 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.710 0.290 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.710 0.290 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.710 0.290 0.000
T00-T07 Injuries involving multiple body regions
0.710 0.290 0.000
S10-S19 Injuries to the neck
0.710 0.290 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.709 0.291 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.708 0.292 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.708 0.292 0.000
M06.8 Other specified rheumatoid arthritis
0.707 0.293 0.000
M06.4 Inflammatory polyarthropathy
0.707 0.293 0.000
M06.3 Rheumatoid nodule
0.707 0.293 0.000
M06.2 Rheumatoid bursitis
0.707 0.293 0.000
M06.1 Adult-onset Still's disease
0.707 0.293 0.000
J42 Unspecified chronic bronchitis
0.706 0.294 0.000
I38 Endocarditis, valve unspecified
0.706 0.294 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.705 0.295 0.000
I63 Cerebral infarction
0.705 0.295 0.000
Z76 Persons encountering health services in other circumstances
0.705 0.295 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.705 0.295 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.703 0.297 0.000
G30-G32 Other degenerative diseases of the nervous system
0.703 0.297 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.702 0.297 0.000
N04.9 Unspecified
0.702 0.298 0.000
S06 Intracranial injury
0.702 0.298 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.702 0.298 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.702 0.298 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.702 0.298 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.702 0.298 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.702 0.298 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.702 0.298 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.702 0.298 0.000
K14 Diseases of tongue
0.701 0.299 0.000
N39.0 Urinary tract infection, site not specified
0.699 0.301 0.000
N37 Urethral disorders in diseases classified elsewhere
0.699 0.301 0.000
N34 Urethritis and urethral syndrome
0.699 0.301 0.000
N33 Bladder disorders in diseases classified elsewhere
0.699 0.301 0.000
Z03.9 Observation for suspected disease or condition, unspecified
0.698 0.302 0.000
N39.9 Disorder of urinary system, unspecified
0.698 0.302 0.000
F48 Other neurotic disorders
0.698 0.302 0.000
F44 Dissociative [conversion] disorders
0.698 0.302 0.000
F42 Obsessive-compulsive disorder
0.698 0.302 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.697 0.302 0.000
K63.2 Fistula of intestine
0.697 0.303 0.000
M10.99 Gout, unspecified (Site unspecified)
0.696 0.304 0.000
M80 Osteoporosis with pathological fracture
0.696 0.304 0.000
I05 Rheumatic mitral valve diseases
0.695 0.305 0.000
M13 Other arthritis
0.694 0.306 0.000
N17-N19 Renal failure
0.694 0.306 0.000
F41.9 Anxiety disorder, unspecified
0.694 0.306 0.000
S02 Fracture of skull and facial bones
0.693 0.307 0.000
I51.7 Cardiomegaly
0.693 0.307 0.000
M65 Synovitis and tenosynovitis
0.692 0.308 0.000
I46 Cardiac arrest
0.692 0.308 0.000
K11.6 Mucocele of salivary gland
0.692 0.308 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.691 0.309 0.000
R41.3 Other amnesia
0.691 0.309 0.000
M11 Other crystal arthropathies
0.689 0.310 0.000
G47.3 Sleep apnoea
0.689 0.311 0.000
N36 Other disorders of urethra
0.688 0.311 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.688 0.312 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.687 0.313 0.000
G44 Other headache syndromes
0.686 0.314 0.000
S68 Traumatic amputation of wrist and hand
0.686 0.314 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.685 0.315 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.685 0.315 0.000
G62.9 Polyneuropathy, unspecified
0.685 0.315 0.000
M07 Psoriatic and enteropathic arthropathies
0.685 0.315 0.000
I08 Multiple valve diseases
0.685 0.315 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.684 0.316 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.684 0.316 0.000
D00-D09 In situ neoplasms
0.684 0.316 0.000
R63 Symptoms and signs concerning food and fluid intake
0.684 0.316 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.683 0.317 0.000
R47-R49 Symptoms and signs involving speech and voice
0.683 0.317 0.000
N05 Unspecified nephritic syndrome
0.682 0.317 0.000
N23 Unspecified renal colic
0.682 0.318 0.000
M45 Ankylosing spondylitis
0.682 0.318 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.682 0.318 0.000
Z71.3 Dietary counselling and surveillance
0.681 0.319 0.000
T93 Sequelae of injuries of lower limb
0.681 0.319 0.000
R45.1 Restlessness and agitation
0.681 0.319 0.000
N61 Inflammatory disorders of breast
0.681 0.319 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.680 0.319 0.000
I44 Atrioventricular and left bundle-branch block
0.680 0.320 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.680 0.320 0.000
C44.7 Skin of lower limb, including hip
0.680 0.320 0.000
F32 Depressive episode
0.680 0.320 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.679 0.320 0.000
Z71.8 Other specified counselling
0.679 0.321 0.000
T90.5 Sequelae of intracranial injury
0.679 0.321 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.679 0.321 0.000
K13.0 Diseases of lips
0.679 0.321 0.000
K61 Abscess of anal and rectal regions
0.679 0.321 0.000
T90.9 Sequelae of unspecified injury of head
0.678 0.322 0.000
S70-S79 Injuries to the hip and thigh
0.678 0.322 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.677 0.323 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.677 0.323 0.000
B99-B99 Other infectious diseases
0.676 0.323 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.676 0.323 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.676 0.323 0.000
B65-B83 Helminthiases
0.676 0.323 0.000
B50-B64 Protozoal diseases
0.676 0.323 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.676 0.323 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.676 0.323 0.000
A75-A79 Rickettsioses
0.676 0.323 0.000
A70-A74 Other diseases caused by chlamydiae
0.676 0.323 0.000
A65-A69 Other spirochaetal diseases
0.676 0.323 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.676 0.323 0.000
A20-A28 Certain zoonotic bacterial diseases
0.676 0.323 0.000
A15-A19 Tuberculosis
0.676 0.323 0.000
Z72.9 Problem related to lifestyle, unspecified
0.676 0.324 0.000
Z72.8 Other problems related to lifestyle
0.676 0.324 0.000
Z72.6 Gambling and betting
0.676 0.324 0.000
Z72.5 High-risk sexual behaviour
0.676 0.324 0.000
Z72.4 Inappropriate diet and eating habits
0.676 0.324 0.000
Z72.3 Lack of physical exercise
0.676 0.324 0.000
Z72.2 Drug use
0.676 0.324 0.000
K38 Other diseases of appendix
0.676 0.324 0.000
K90-K93 Other diseases of the digestive system
0.676 0.324 0.000
K10 Other diseases of jaws
0.675 0.325 0.000
K09 Cysts of oral region, not elsewhere classified
0.675 0.325 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.675 0.325 0.000
K03 Other diseases of hard tissues of teeth
0.675 0.325 0.000
K00 Disorders of tooth development and eruption
0.675 0.325 0.000
N35 Urethral stricture
0.675 0.325 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.675 0.325 0.000
A30-A49 Other bacterial diseases
0.674 0.326 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.673 0.327 0.000
K59 Other functional intestinal disorders
0.673 0.327 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.673 0.327 0.000
N02.9 Unspecified
0.672 0.328 0.000
N32.8 Other specified disorders of bladder
0.672 0.328 0.000
T92 Sequelae of injuries of upper limb
0.672 0.328 0.000
N30.9 Cystitis, unspecified
0.672 0.328 0.000
I49 Other cardiac arrhythmias
0.671 0.329 0.000
Z10 Routine general health check-up of defined subpopulation
0.671 0.329 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.671 0.329 0.000
G43 Migraine
0.671 0.329 0.000
K08.3 Retained dental root
0.671 0.329 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.671 0.329 0.000
G95 Other diseases of spinal cord
0.670 0.330 0.000
I27.0 Primary pulmonary hypertension
0.670 0.330 0.000
T66-T78 Other and unspecified effects of external causes
0.669 0.331 0.000
M48.0 Spinal stenosis
0.669 0.331 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.669 0.331 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.669 0.331 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.669 0.331 0.000
F33 Recurrent depressive disorder
0.669 0.331 0.000
Z74 Problems related to care-provider dependency
0.669 0.331 0.000
M85 Other disorders of bone density and structure
0.668 0.332 0.000
M84 Disorders of continuity of bone
0.668 0.332 0.000
M83 Adult osteomalacia
0.668 0.332 0.000
M82 Osteoporosis in diseases classified elsewhere
0.668 0.332 0.000
K07 Dentofacial anomalies [including malocclusion]
0.668 0.332 0.000
S32 Fracture of lumbar spine and pelvis
0.668 0.332 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.667 0.332 0.000
Z03.6 Observation for suspected toxic effect from ingested substance
0.667 0.333 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.667 0.333 0.000
Z03.0 Observation for suspected tuberculosis
0.667 0.333 0.000
K36 Other appendicitis
0.666 0.334 0.000
R59 Enlarged lymph nodes
0.666 0.334 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.665 0.335 0.000
I51.8 Other ill-defined heart diseases
0.664 0.336 0.000
N39.2 Orthostatic proteinuria, unspecified
0.664 0.336 0.000
N39.1 Persistent proteinuria, unspecified
0.664 0.336 0.000
C44.6 Skin of upper limb, including shoulder
0.664 0.336 0.000
C50-C50 Malignant neoplasm of breast
0.664 0.336 0.000
G81.9 Hemiplegia, unspecified
0.664 0.336 0.000
B34 Viral infection of unspecified site
0.663 0.337 0.000
I65.2 Occlusion and stenosis of carotid artery
0.662 0.338 0.000
I45 Other conduction disorders
0.662 0.338 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.662 0.338 0.000
R73 Elevated blood glucose level
0.661 0.339 0.000
S62.3 Fracture of other metacarpal bone
0.661 0.339 0.000
K55.9 Vascular disorder of intestine, unspecified
0.661 0.339 0.000
A00-A09 Intestinal infectious diseases
0.661 0.339 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.660 0.339 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.660 0.340 0.000
I67.1 Cerebral aneurysm, nonruptured
0.660 0.340 0.000
K11.8 Other diseases of salivary glands
0.660 0.340 0.000
S08 Traumatic amputation of part of head
0.660 0.340 0.000
S07 Crushing injury of head
0.660 0.340 0.000
S05 Injury of eye and orbit
0.660 0.340 0.000
S04 Injury of cranial nerves
0.660 0.340 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.660 0.340 0.000
M46 Other inflammatory spondylopathies
0.659 0.341 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.658 0.342 0.000
I69.3 Sequelae of cerebral infarction
0.658 0.342 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.658 0.342 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.658 0.342 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.658 0.342 0.000
K05 Gingivitis and periodontal diseases
0.657 0.343 0.000
K58 Irritable bowel syndrome
0.657 0.343 0.000
Z03.1 Observation for suspected malignant neoplasm
0.657 0.343 0.000
K02.9 Dental caries, unspecified
0.656 0.344 0.000
R46 Symptoms and signs involving appearance and behaviour
0.656 0.344 0.000
R43 Disturbances of smell and taste
0.656 0.344 0.000
M15-M19 Arthrosis
0.656 0.344 0.000
F41.8 Other specified anxiety disorders
0.655 0.345 0.000
F41.3 Other mixed anxiety disorders
0.655 0.345 0.000
F41.1 Generalised anxiety disorder
0.655 0.345 0.000
F20 Schizophrenia
0.655 0.345 0.000
S69 Other and unspecified injuries of wrist and hand
0.655 0.345 0.000
S67 Crushing injury of wrist and hand
0.655 0.345 0.000
S65 Injury of blood vessels at wrist and hand level
0.655 0.345 0.000
S60 Superficial injury of wrist and hand
0.655 0.345 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.653 0.347 0.000
C44.8 Overlapping lesion of skin
0.653 0.347 0.000
C44.0 Skin of lip
0.653 0.347 0.000
N60 Benign mammary dysplasia
0.653 0.347 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.652 0.347 0.000
Z51.3 Blood transfusion without reported diagnosis
0.652 0.348 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.651 0.349 0.000
I31 Other diseases of pericardium
0.651 0.349 0.000
C44.4 Skin of scalp and neck
0.651 0.349 0.000
T98 Sequelae of other and unspecified effects of external causes
0.650 0.349 0.000
T95 Sequelae of burns, corrosions and frostbite
0.650 0.349 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.650 0.349 0.000
T91 Sequelae of injuries of neck and trunk
0.650 0.349 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.650 0.349 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.650 0.349 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.650 0.350 0.000
V80-V89 Other land transport accidents
0.650 0.350 0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.649 0.351 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.649 0.351 0.000
J37 Chronic laryngitis and laryngotracheitis
0.649 0.351 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.649 0.351 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.648 0.351 0.000
N06 Isolated proteinuria with specified morphological lesion
0.648 0.351 0.000
N01 Rapidly progressive nephritic syndrome
0.648 0.351 0.000
N00 Acute nephritic syndrome
0.648 0.351 0.000
G83 Other paralytic syndromes
0.648 0.352 0.000
J17 Pneumonia in diseases classified elsewhere
0.648 0.352 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.648 0.352 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.648 0.352 0.000
J12 Viral pneumonia, not elsewhere classified
0.648 0.352 0.000
J10 Influenza due to identified influenza virus
0.648 0.352 0.000
J14 Pneumonia due to Haemophilus influenzae
0.648 0.352 0.000
J09 Influenza due to certain identified influenza virus
0.648 0.352 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.647 0.353 0.000
Z48.9 Surgical follow-up care, unspecified
0.647 0.353 0.000
K63.4 Enteroptosis
0.646 0.353 0.000
K63.0 Abscess of intestine
0.646 0.353 0.000
I10-I15 Hypertensive diseases
0.646 0.354 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.646 0.354 0.000
J96 Respiratory failure, not elsewhere classified
0.646 0.354 0.000
I07 Rheumatic tricuspid valve diseases
0.646 0.354 0.000
N32.0 Bladder-neck obstruction
0.646 0.354 0.000
J95.8 Other postprocedural respiratory disorders
0.645 0.355 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.644 0.356 0.000
J45 Asthma
0.644 0.356 0.000
Z54 Convalescence
0.643 0.357 0.000
Z52 Donors of organs and tissues
0.643 0.357 0.000
Z49 Care involving dialysis
0.643 0.357 0.000
Z44 Fitting and adjustment of external prosthetic device
0.643 0.357 0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified
0.642 0.357 0.000
Z46 Fitting and adjustment of other devices
0.642 0.358 0.000
F60 Specific personality disorders
0.642 0.358 0.000
J43 Emphysema
0.642 0.358 0.000
N10 Acute tubulo-interstitial nephritis
0.642 0.358 0.000
G20-G26 Extrapyramidal and movement disorders
0.642 0.358 0.000
G40.9 Epilepsy, unspecified
0.641 0.359 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.641 0.359 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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