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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs73178603
log Bayes Factor = 12.117
Chromosome 7   position 155,065,202  (GRCh37) Explore rs73178603 on Ensembl!
Variant rs73178603 is part of Cluster X0225

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I30-I52 Other forms of heart disease
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
F30-F39 Mood [affective] disorders
1.000 0.000 0.000
F32 Depressive episode
1.000 0.000 0.000
F32.9 Depressive episode, unspecified
1.000 0.000 0.000
N30-N39 Other diseases of urinary system
0.996 0.004 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.985 0.015 0.000
S00-S09 Injuries to the head
0.983 0.017 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.979 0.021 0.000
N00-N08 Glomerular diseases
0.978 0.022 0.000
N32 Other disorders of bladder
0.977 0.023 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.973 0.027 0.000
I45 Other conduction disorders
0.973 0.027 0.000
N17-N19 Renal failure
0.973 0.027 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.965 0.035 0.000
N03 Chronic nephritic syndrome
0.961 0.039 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.959 0.041 0.000
I35 Nonrheumatic aortic valve disorders
0.954 0.046 0.000
I45.1 Other and unspecified right bundle-branch block
0.953 0.047 0.000
N18 Chronic renal failure
0.949 0.051 0.000
N03.9 Unspecified
0.949 0.051 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.943 0.057 0.000
S00 Superficial injury of head
0.942 0.058 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.941 0.059 0.000
N30 Cystitis
0.939 0.061 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.937 0.063 0.000
F41 Other anxiety disorders
0.934 0.066 0.000
I34 Nonrheumatic mitral valve disorders
0.933 0.067 0.000
I38 Endocarditis, valve unspecified
0.933 0.067 0.000
M20-M25 Other joint disorders
0.924 0.076 0.000
I35.0 Aortic (valve) stenosis
0.917 0.083 0.000
E10-E14 Diabetes mellitus
0.917 0.083 0.000
I42 Cardiomyopathy
0.915 0.084 0.000
N32.0 Bladder-neck obstruction
0.907 0.093 0.000
S00.9 Superficial injury of head, part unspecified
0.904 0.096 0.000
I95 Hypotension
0.896 0.104 0.000
I50 Heart failure
0.896 0.104 0.000
N39 Other disorders of urinary system
0.895 0.105 0.000
N32.3 Diverticulum of bladder
0.893 0.107 0.000
I51 Complications and ill-defined descriptions of heart disease
0.884 0.116 0.000
M05-M14 Inflammatory polyarthropathies
0.882 0.118 0.000
N18.0 End-stage renal disease
0.880 0.120 0.000
M25 Other joint disorders, not elsewhere classified
0.877 0.123 0.000
M35 Other systemic involvement of connective tissue
0.872 0.128 0.000
S70-S79 Injuries to the hip and thigh
0.865 0.135 0.000
I34.1 Mitral (valve) prolapse
0.862 0.138 0.000
Chapter XX External causes of morbidity and mortality
0.859 0.141 0.000
I50.9 Heart failure, unspecified
0.859 0.141 0.000
F43 Reaction to severe stress, and adjustment disorders
0.857 0.143 0.000
N10-N16 Renal tubulo-interstitial diseases
0.856 0.144 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.854 0.146 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.850 0.150 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.850 0.150 0.000
E10 Insulin-dependent diabetes mellitus
0.850 0.150 0.000
F32.0 Mild depressive episode
0.848 0.152 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.847 0.153 0.000
I44 Atrioventricular and left bundle-branch block
0.846 0.154 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.846 0.154 0.000
S09 Other and unspecified injuries of head
0.843 0.157 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.843 0.157 0.000
S02 Fracture of skull and facial bones
0.841 0.159 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.841 0.159 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.840 0.160 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.836 0.164 0.000
S50-S59 Injuries to the elbow and forearm
0.836 0.164 0.000
N18.3 Chronic kidney disease, stage 3
0.832 0.168 0.000
F60-F69 Disorders of adult personality and behaviour
0.828 0.172 0.000
N32.8 Other specified disorders of bladder
0.826 0.174 0.000
I49 Other cardiac arrhythmias
0.825 0.175 0.000
N18.4 Chronic kidney disease, stage 4
0.825 0.175 0.000
I36 Nonrheumatic tricuspid valve disorders
0.821 0.179 0.000
I42.0 Dilated cardiomyopathy
0.820 0.180 0.000
E11 Non-insulin-dependent diabetes mellitus
0.815 0.185 0.000
N39.8 Other specified disorders of urinary system
0.809 0.191 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.808 0.192 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.807 0.193 0.000
F41.2 Mixed anxiety and depressive disorder
0.807 0.193 0.000
M80-M85 Disorders of bone density and structure
0.805 0.195 0.000
N30.3 Trigonitis
0.805 0.195 0.000
S80-S89 Injuries to the knee and lower leg
0.804 0.196 0.000
F33 Recurrent depressive disorder
0.803 0.197 0.000
F32.1 Moderate depressive episode
0.802 0.198 0.000
I95.9 Hypotension, unspecified
0.799 0.201 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.798 0.202 0.000
I44.0 Atrioventricular block, first degree
0.795 0.205 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.794 0.206 0.000
N25-N29 Other disorders of kidney and ureter
0.792 0.208 0.000
I51.7 Cardiomegaly
0.791 0.209 0.000
S20-S29 Injuries to the thorax
0.789 0.210 0.000
I47 Paroxysmal tachycardia
0.787 0.213 0.000
N39.0 Urinary tract infection, site not specified
0.786 0.214 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.785 0.215 0.000
F80-F89 Disorders of psychological development
0.783 0.217 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.782 0.218 0.000
M35.3 Polymyalgia rheumatica
0.782 0.218 0.000
I37 Pulmonary valve disorders
0.781 0.219 0.000
E14 Unspecified diabetes mellitus
0.779 0.221 0.000
M34 Systemic sclerosis
0.778 0.222 0.000
M13 Other arthritis
0.777 0.223 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.777 0.223 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.776 0.224 0.000
N30.9 Cystitis, unspecified
0.776 0.224 0.000
F42 Obsessive-compulsive disorder
0.776 0.224 0.000
S90-S99 Injuries to the ankle and foot
0.776 0.224 0.000
S00.3 Superficial injury of nose
0.774 0.226 0.000
N99-N99 Other disorders of the genitourinary system
0.774 0.226 0.000
M35.0 Sicca syndrome [Sjogren]
0.773 0.227 0.000
E10.3 With ophthalmic complications
0.771 0.229 0.000
N19 Unspecified renal failure
0.766 0.234 0.000
I95.1 Orthostatic hypotension
0.765 0.235 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.764 0.236 0.000
I49.8 Other specified cardiac arrhythmias
0.764 0.236 0.000
T40.2 Other opioids
0.760 0.240 0.000
I60-I69 Cerebrovascular diseases
0.760 0.240 0.000
F40 Phobic anxiety disorders
0.758 0.242 0.000
M91-M94 Chondropathies
0.758 0.242 0.000
T66-T78 Other and unspecified effects of external causes
0.758 0.242 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.757 0.243 0.000
I34.0 Mitral (valve) insufficiency
0.757 0.243 0.000
S00.7 Multiple superficial injuries of head
0.755 0.245 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.754 0.246 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.753 0.247 0.000
N60-N64 Disorders of breast
0.753 0.247 0.000
Chapter XXII Codes for special purposes
0.753 0.247 0.000
M25.5 Pain in joint
0.753 0.247 0.000
E00-E07 Disorders of thyroid gland
0.751 0.249 0.000
M60-M63 Disorders of muscles
0.751 0.249 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.750 0.250 0.000
N30.1 Interstitial cystitis (chronic)
0.749 0.251 0.000
N18.5 Chronic kidney disease, stage 5
0.748 0.252 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.744 0.256 0.000
I27 Other pulmonary heart diseases
0.744 0.256 0.000
S09.9 Unspecified injury of head
0.743 0.257 0.000
T86 Failure and rejection of transplanted organs and tissues
0.742 0.258 0.000
I42.9 Cardiomyopathy, unspecified
0.742 0.258 0.000
N34 Urethritis and urethral syndrome
0.738 0.262 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.738 0.262 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.737 0.263 0.000
I51.4 Myocarditis, unspecified
0.736 0.264 0.000
F41.1 Generalised anxiety disorder
0.736 0.264 0.000
M22 Disorders of patella
0.735 0.265 0.000
S06 Intracranial injury
0.734 0.266 0.000
T79-T79 Certain early complications of trauma
0.734 0.266 0.000
I33 Acute and subacute endocarditis
0.734 0.266 0.000
M25.7 Osteophyte
0.731 0.269 0.000
N30.8 Other cystitis
0.728 0.272 0.000
I30 Acute pericarditis
0.727 0.273 0.000
I95.2 Hypotension due to drugs
0.726 0.274 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.726 0.274 0.000
N05 Unspecified nephritic syndrome
0.724 0.276 0.000
I35.1 Aortic (valve) insufficiency
0.724 0.276 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.723 0.277 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.723 0.277 0.000
W00-W19 Falls
0.723 0.277 0.000
M24 Other specific joint derangements
0.722 0.277 0.000
M06 Other rheumatoid arthritis
0.721 0.279 0.000
E11.3 With ophthalmic complications
0.720 0.280 0.000
I45.6 Preexcitation syndrome
0.720 0.280 0.000
T39.1 4-Aminophenol derivatives
0.719 0.281 0.000
N39.3 Stress incontinence
0.719 0.281 0.000
I31 Other diseases of pericardium
0.719 0.281 0.000
F43.0 Acute stress reaction
0.718 0.282 0.000
S82 Fracture of lower leg, including ankle
0.718 0.282 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.717 0.283 0.000
Chapter VIII Diseases of the ear and mastoid process
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
F99-F99 Unspecified mental disorder
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
F38 Other mood [affective] disorders
0.717 0.283 0.000
F34 Persistent mood [affective] disorders
0.717 0.283 0.000
F30 Manic episode
0.717 0.283 0.000
F39 Unspecified mood [affective] disorder
0.717 0.283 0.000
F32.8 Other depressive episodes
0.717 0.283 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.716 0.284 0.000
N37 Urethral disorders in diseases classified elsewhere
0.714 0.286 0.000
N33 Bladder disorders in diseases classified elsewhere
0.714 0.286 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.713 0.287 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.712 0.288 0.000
N36 Other disorders of urethra
0.711 0.289 0.000
N30.2 Other chronic cystitis
0.709 0.290 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.709 0.291 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.706 0.294 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.706 0.294 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.706 0.294 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.706 0.294 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.706 0.294 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.706 0.294 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.706 0.294 0.000
T36 Poisoning by systemic antibiotics
0.706 0.294 0.000
T82.1 Mechanical complication of cardiac electronic device
0.706 0.294 0.000
S08 Traumatic amputation of part of head
0.705 0.295 0.000
S07 Crushing injury of head
0.705 0.295 0.000
S05 Injury of eye and orbit
0.705 0.295 0.000
S04 Injury of cranial nerves
0.705 0.295 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.705 0.295 0.000
F43.2 Adjustment disorders
0.704 0.295 0.000
F60 Specific personality disorders
0.704 0.296 0.000
I80 Phlebitis and thrombophlebitis
0.704 0.296 0.000
M13.9 Arthritis, unspecified
0.703 0.297 0.000
F48 Other neurotic disorders
0.702 0.298 0.000
F44 Dissociative [conversion] disorders
0.702 0.298 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.701 0.298 0.000
N06 Isolated proteinuria with specified morphological lesion
0.701 0.298 0.000
N01 Rapidly progressive nephritic syndrome
0.701 0.298 0.000
N00 Acute nephritic syndrome
0.701 0.298 0.000
I51.8 Other ill-defined heart diseases
0.701 0.299 0.000
E10.4 With neurological complications
0.700 0.300 0.000
N32.4 Rupture of bladder, nontraumatic
0.700 0.300 0.000
N32.2 Vesical fistula, not elsewhere classified
0.700 0.300 0.000
N32.1 Vesicointestinal fistula
0.700 0.300 0.000
N02 Recurrent and persistent haematuria
0.699 0.301 0.000
M25.4 Effusion of joint
0.699 0.301 0.000
I45.9 Conduction disorder, unspecified
0.698 0.302 0.000
T87 Complications peculiar to reattachment and amputation
0.698 0.302 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.698 0.302 0.000
I45.8 Other specified conduction disorders
0.698 0.302 0.000
I45.4 Nonspecific intraventricular block
0.698 0.302 0.000
I45.3 Trifascicular block
0.698 0.302 0.000
I45.2 Bifascicular block
0.698 0.302 0.000
I45.0 Right fascicular block
0.698 0.302 0.000
M86-M90 Other osteopathies
0.698 0.302 0.000
E14.9 Without complications
0.698 0.302 0.000
E65-E68 Obesity and other hyperalimentation
0.697 0.303 0.000
N04 Nephrotic syndrome
0.695 0.305 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.693 0.307 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.693 0.307 0.000
E11.4 With neurological complications
0.693 0.307 0.000
M00-M03 Infectious arthropathies
0.692 0.308 0.000
M84 Disorders of continuity of bone
0.690 0.310 0.000
N03.8 Other
0.689 0.311 0.000
N03.7 Diffuse crescentic glomerulonephritis
0.689 0.311 0.000
N03.6 Dense deposit disease
0.689 0.311 0.000
N03.5 Diffuse mesangiocapillary glomerulonephritis
0.689 0.311 0.000
N03.4 Diffuse endocapillary proliferative glomerulonephritis
0.689 0.311 0.000
N03.3 Diffuse mesangial proliferative glomerulonephritis
0.689 0.311 0.000
N03.2 Diffuse membranous glomerulonephritis
0.689 0.311 0.000
N03.1 Focal and segmental glomerular lesions
0.689 0.311 0.000
N03.0 Minor glomerular abnormality
0.689 0.311 0.000
I45.5 Other specified heart block
0.688 0.311 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.687 0.313 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.687 0.313 0.000
N20-N23 Urolithiasis
0.686 0.314 0.000
E50-E64 Other nutritional deficiencies
0.685 0.315 0.000
I35.8 Other aortic valve disorders
0.683 0.316 0.000
M65-M68 Disorders of synovium and tendon
0.683 0.317 0.000
N18.8 Other chronic renal failure
0.681 0.319 0.000
N18.1 Chronic kidney disease, stage 1
0.681 0.319 0.000
Chapter VI Diseases of the nervous system
0.680 0.320 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.680 0.320 0.000
F31 Bipolar affective disorder
0.679 0.321 0.000
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere
0.679 0.321 0.000
M11 Other crystal arthropathies
0.677 0.323 0.000
M25.56 Pain in joint (Lower leg)
0.677 0.323 0.000
S71 Open wound of hip and thigh
0.676 0.324 0.000
F41.9 Anxiety disorder, unspecified
0.676 0.324 0.000
S00.5 Superficial injury of lip and oral cavity
0.676 0.324 0.000
S00.4 Superficial injury of ear
0.676 0.324 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.676 0.324 0.000
N17 Acute renal failure
0.674 0.326 0.000
I99 Other and unspecified disorders of circulatory system
0.674 0.326 0.000
N30.4 Irradiation cystitis
0.674 0.326 0.000
N30.0 Acute cystitis
0.674 0.326 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.673 0.327 0.000
S79 Other and unspecified injuries of hip and thigh
0.673 0.327 0.000
M25.9 Joint disorder, unspecified
0.672 0.328 0.000
S52 Fracture of forearm
0.672 0.328 0.000
E40-E46 Malnutrition
0.672 0.328 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.671 0.329 0.000
T42.4 Benzodiazepines
0.671 0.329 0.000
I47.2 Ventricular tachycardia
0.671 0.329 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.670 0.330 0.000
F41.8 Other specified anxiety disorders
0.669 0.330 0.000
F41.3 Other mixed anxiety disorders
0.669 0.330 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.669 0.331 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.669 0.331 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.669 0.331 0.000
S70 Superficial injury of hip and thigh
0.669 0.331 0.000
S02.0 Fracture of vault of skull
0.668 0.332 0.000
N76 Other inflammation of vagina and vulva
0.666 0.334 0.000
S00.8 Superficial injury of other parts of head
0.666 0.334 0.000
S51 Open wound of forearm
0.665 0.335 0.000
S72 Fracture of femur
0.665 0.335 0.000
T45.0 Antiallergic and antiemetic drugs
0.664 0.336 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.662 0.338 0.000
M33 Dermatopolymyositis
0.662 0.338 0.000
M32 Systemic lupus erythematosus
0.662 0.338 0.000
M30 Polyarteritis nodosa and related conditions
0.662 0.338 0.000
N64 Other disorders of breast
0.661 0.339 0.000
S02.1 Fracture of base of skull
0.661 0.339 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.660 0.340 0.000
M05 Seropositive rheumatoid arthritis
0.660 0.340 0.000
E10.5 With peripheral circulatory complications
0.659 0.341 0.000
N10 Acute tubulo-interstitial nephritis
0.659 0.341 0.000
M70-M79 Other soft tissue disorders
0.658 0.342 0.000
M25.3 Other instability of joint
0.658 0.342 0.000
E12 Malnutrition-related diabetes mellitus
0.657 0.342 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.657 0.343 0.000
I42.8 Other cardiomyopathies
0.656 0.344 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.656 0.344 0.000
I42.6 Alcoholic cardiomyopathy
0.656 0.344 0.000
I42.5 Other restrictive cardiomyopathy
0.656 0.344 0.000
I42.4 Endocardial fibroelastosis
0.656 0.344 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.656 0.344 0.000
I42.2 Other hypertrophic cardiomyopathy
0.656 0.344 0.000
X60-X84 Intentional self-harm
0.656 0.344 0.000
F03 Unspecified dementia
0.656 0.344 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.655 0.345 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.655 0.345 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.653 0.347 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.653 0.347 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.652 0.348 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.652 0.348 0.000
E13 Other specified diabetes mellitus
0.650 0.350 0.000
I49.5 Sick sinus syndrome
0.646 0.354 0.000
N75 Diseases of Bartholin's gland
0.646 0.354 0.000
E20-E35 Disorders of other endocrine glands
0.646 0.354 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.645 0.355 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.645 0.355 0.000
Chapter X Diseases of the respiratory system
0.645 0.355 0.000
F52.2 Failure of genital response
0.644 0.356 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.643 0.357 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.643 0.357 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.643 0.357 0.000
N32.9 Bladder disorder, unspecified
0.642 0.357 0.000
I35.9 Aortic valve disorder, unspecified
0.642 0.358 0.000
I95.8 Other hypotension
0.642 0.358 0.000
I95.0 Idiopathic hypotension
0.642 0.358 0.000
N39.2 Orthostatic proteinuria, unspecified
0.641 0.359 0.000
N39.1 Persistent proteinuria, unspecified
0.641 0.359 0.000
S02.8 Fractures of other skull and facial bones
0.641 0.359 0.000
Chapter I Certain infectious and parasitic diseases
0.640 0.360 0.000
E07 Other disorders of thyroid
0.639 0.361 0.000
X20-X29 Contact with venomous animals and plants
0.638 0.362 0.000
M34.1 CR(E)ST syndrome
0.637 0.363 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.637 0.363 0.000
E11.2 With renal complications
0.636 0.364 0.000
M10 Gout
0.635 0.365 0.000
I51.6 Cardiovascular disease, unspecified
0.633 0.366 0.000
I51.5 Myocardial degeneration
0.633 0.366 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.633 0.366 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.633 0.366 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.633 0.366 0.000
I51.0 Cardiac septal defect, acquired
0.633 0.366 0.000
F45 Somatoform disorders
0.633 0.367 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.633 0.367 0.000
M14 Arthropathies in other diseases classified elsewhere
0.632 0.368 0.000
M12 Other specific arthropathies
0.632 0.368 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.632 0.368 0.000
M08 Juvenile arthritis
0.632 0.368 0.000
I50.1 Left ventricular failure
0.632 0.368 0.000
E10.9 Without complications
0.631 0.369 0.000
I60 Subarachnoid haemorrhage
0.631 0.369 0.000
M21 Other acquired deformities of limbs
0.631 0.369 0.000
F00 Dementia in Alzheimer's disease
0.631 0.369 0.000
M81 Osteoporosis without pathological fracture
0.631 0.369 0.000
F42.9 Obsessive-compulsive disorder, unspecified
0.630 0.370 0.000
Y52 Agents primarily affecting the cardiovascular system
0.630 0.370 0.000
M45-M49 Spondylopathies
0.630 0.370 0.000
M25.8 Other specified joint disorders
0.629 0.371 0.000
M25.2 Flail joint
0.629 0.371 0.000
M25.1 Fistula of joint
0.629 0.371 0.000
M25.0 Haemarthrosis
0.629 0.371 0.000
F80 Specific developmental disorders of speech and language
0.627 0.373 0.000
S01 Open wound of head
0.627 0.373 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.626 0.374 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.626 0.374 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.625 0.374 0.000
M35.8 Other specified systemic involvement of connective tissue
0.625 0.374 0.000
M35.7 Hypermobility syndrome
0.625 0.374 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.625 0.374 0.000
M35.5 Multifocal fibrosclerosis
0.625 0.374 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.625 0.374 0.000
M35.2 Behcet's disease
0.625 0.374 0.000
M35.1 Other overlap syndromes
0.625 0.374 0.000
M06.9 Rheumatoid arthritis, unspecified
0.625 0.375 0.000
I37.1 Pulmonary valve insufficiency
0.625 0.375 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.623 0.376 0.000
S02.2 Fracture of nasal bones
0.622 0.378 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.621 0.379 0.000
I78 Diseases of capillaries
0.621 0.379 0.000
I27.2 Other secondary pulmonary hypertension
0.620 0.379 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.620 0.380 0.000
S78 Traumatic amputation of hip and thigh
0.620 0.380 0.000
S77 Crushing injury of hip and thigh
0.620 0.380 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.620 0.380 0.000
S75 Injury of blood vessels at hip and thigh level
0.620 0.380 0.000
S74 Injury of nerves at hip and thigh level
0.620 0.380 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.620 0.380 0.000
N61 Inflammatory disorders of breast
0.618 0.382 0.000
N18.2 Chronic kidney disease, stage 2
0.617 0.382 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.616 0.384 0.000
Y35-Y36 Legal intervention and operations of war
0.616 0.384 0.000
Y10-Y34 Event of undetermined intent
0.616 0.384 0.000
Y00-Y09 Assault
0.616 0.384 0.000
X85-X99 Assault
0.616 0.384 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.616 0.384 0.000
X50-X57 Overexertion, travel and privation
0.616 0.384 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.616 0.384 0.000
X30-X39 Exposure to forces of nature
0.616 0.384 0.000
X10-X19 Contact with heat and hot substances
0.616 0.384 0.000
X00-X09 Exposure to smoke, fire and flames
0.616 0.384 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.616 0.384 0.000
W75-W84 Other accidental threats to breathing
0.616 0.384 0.000
W65-W74 Accidental drowning and submersion
0.616 0.384 0.000
W50-W64 Exposure to animate mechanical forces
0.616 0.384 0.000
V98-V99 Other and unspecified transport accidents
0.616 0.384 0.000
V95-V97 Air and space transport accidents
0.616 0.384 0.000
V90-V94 Water transport accidents
0.616 0.384 0.000
V80-V89 Other land transport accidents
0.616 0.384 0.000
V70-V79 Bus occupant injured in transport accident
0.616 0.384 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.616 0.384 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.616 0.384 0.000
V40-V49 Car occupant injured in transport accident
0.616 0.384 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.616 0.384 0.000
V01-V09 Pedestrian injured in transport accident
0.616 0.384 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.615 0.385 0.000
F43.9 Reaction to severe stress, unspecified
0.615 0.385 0.000
F43.8 Other reactions to severe stress
0.615 0.385 0.000
F43.1 Posttraumatic stress disorder
0.615 0.385 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.614 0.386 0.000
N15 Other renal tubulo-interstitial diseases
0.614 0.386 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.614 0.386 0.000
N11 Chronic tubulo-interstitial nephritis
0.614 0.386 0.000
I49.3 Ventricular premature depolarisation
0.613 0.386 0.000
M34.9 Systemic sclerosis, unspecified
0.613 0.386 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.612 0.388 0.000
T40.8 Lysergide [LSD]
0.612 0.388 0.000
T40.7 Cannabis (derivatives)
0.612 0.388 0.000
T40.6 Other and unspecified narcotics
0.612 0.388 0.000
T40.5 Cocaine
0.612 0.388 0.000
T40.4 Other synthetic narcotics
0.612 0.388 0.000
T40.3 Methadone
0.612 0.388 0.000
T40.1 Heroin
0.612 0.388 0.000
T40.0 Opium
0.612 0.388 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.612 0.388 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.612 0.388 0.000
Q60-Q64 Congenital malformations of the urinary system
0.611 0.389 0.000
B35-B49 Mycoses
0.611 0.389 0.000
S60-S69 Injuries to the wrist and hand
0.610 0.389 0.000
M72 Fibroblastic disorders
0.610 0.389 0.000
I28 Other diseases of pulmonary vessels
0.610 0.390 0.000
T50.8 Diagnostic agents
0.610 0.390 0.000
T50.7 Analeptics and opioid receptor antagonists
0.610 0.390 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.610 0.390 0.000
T50.5 Appetite depressants
0.610 0.390 0.000
T50.4 Drugs affecting uric acid metabolism
0.610 0.390 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.610 0.390 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.610 0.390 0.000
T50.1 Loop [high-ceiling] diuretics
0.610 0.390 0.000
T50.0 Mineralocorticoids and their antagonists
0.610 0.390 0.000
E10.8 With unspecified complications
0.609 0.391 0.000
E10.7 With multiple complications
0.609 0.391 0.000
E10.6 With other specified complications
0.609 0.391 0.000
E10.2 With renal complications
0.609 0.391 0.000
E10.0 With coma
0.609 0.391 0.000
V10-V19 Pedal cyclist injured in transport accident
0.608 0.392 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.608 0.392 0.000
S89 Other and unspecified injuries of lower leg
0.608 0.392 0.000
S82.2 Fracture of shaft of tibia
0.608 0.392 0.000
I26 Pulmonary embolism
0.608 0.392 0.000
N71 Inflammatory disease of uterus, except cervix
0.607 0.392 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.607 0.393 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.607 0.393 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.607 0.393 0.000
T82.3 Mechanical complication of other vascular grafts
0.607 0.393 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.607 0.393 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.607 0.393 0.000
S20 Superficial injury of thorax
0.607 0.393 0.000
M40-M43 Deforming dorsopathies
0.607 0.393 0.000
I44.6 Other and unspecified fascicular block
0.606 0.393 0.000
I44.5 Left posterior fascicular block
0.606 0.393 0.000
I44.4 Left anterior fascicular block
0.606 0.393 0.000
I44.3 Other and unspecified atrioventricular block
0.606 0.393 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.606 0.394 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.606 0.394 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.606 0.394 0.000
T42.3 Barbiturates
0.606 0.394 0.000
T42.2 Succinimides and oxazolidinediones
0.606 0.394 0.000
T42.1 Iminostilbenes
0.606 0.394 0.000
T42.0 Hydantoin derivatives
0.606 0.394 0.000
I82 Other venous embolism and thrombosis
0.605 0.395 0.000
S09.8 Other specified injuries of head
0.605 0.395 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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