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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs73195295
log Bayes Factor = 14.6178
Chromosome 13   position 58,551,273  (GRCh37) Explore rs73195295 on Ensembl!
Variant rs73195295 is part of Cluster X0134

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
M06 Other rheumatoid arthritis
0.997 0.003 0.000
Chapter XX External causes of morbidity and mortality
0.997 0.003 0.000
Chapter XI Diseases of the digestive system
0.996 0.004 0.000
M06.9 Rheumatoid arthritis, unspecified
0.995 0.005 0.000
I20-I25 Ischaemic heart diseases
0.989 0.011 0.000
K55-K64 Other diseases of intestines
0.988 0.012 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.986 0.014 0.000
K62 Other diseases of anus and rectum
0.985 0.015 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.980 0.020 0.000
K62.1 Rectal polyp
0.980 0.020 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.980 0.020 0.000
M45-M49 Spondylopathies
0.978 0.022 0.000
M40-M43 Deforming dorsopathies
0.975 0.025 0.000
Chapter VI Diseases of the nervous system
0.973 0.027 0.000
Chapter VIII Diseases of the ear and mastoid process
0.972 0.028 0.000
S60-S69 Injuries to the wrist and hand
0.971 0.029 0.000
I95 Hypotension
0.970 0.030 0.000
I25 Chronic ischaemic heart disease
0.968 0.032 0.000
Chapter V Mental and behavioural disorders
0.965 0.035 0.000
I24 Other acute ischaemic heart diseases
0.963 0.037 0.000
K70-K77 Diseases of liver
0.962 0.038 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.951 0.049 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.950 0.050 0.000
I95.9 Hypotension, unspecified
0.947 0.053 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.945 0.055 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.944 0.056 0.000
K62.6 Ulcer of anus and rectum
0.944 0.056 0.000
I60-I69 Cerebrovascular diseases
0.943 0.057 0.000
M47 Spondylosis
0.942 0.058 0.000
Chapter II Neoplasms
0.934 0.066 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.930 0.070 0.000
E20-E35 Disorders of other endocrine glands
0.929 0.071 0.000
E70-E90 Metabolic disorders
0.927 0.073 0.000
C15-C26 Malignant neoplasms of digestive organs
0.926 0.074 0.000
K63 Other diseases of intestine
0.923 0.077 0.000
K50-K52 Noninfective enteritis and colitis
0.923 0.077 0.000
M43 Other deforming dorsopathies
0.921 0.079 0.000
M13 Other arthritis
0.917 0.083 0.000
K76 Other diseases of liver
0.915 0.085 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.915 0.085 0.000
S61 Open wound of wrist and hand
0.911 0.089 0.000
O00-O08 Pregnancy with abortive outcome
0.911 0.089 0.000
H65-H75 Diseases of middle ear and mastoid
0.909 0.091 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.907 0.093 0.000
W20-W49 Exposure to inanimate mechanical forces
0.901 0.099 0.000
I24.8 Other forms of acute ischaemic heart disease
0.901 0.099 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.899 0.101 0.000
M47.8 Other spondylosis
0.896 0.104 0.000
K52 Other non-infective gastro-enteritis and colitis
0.895 0.105 0.000
C25 Malignant neoplasm of pancreas
0.894 0.106 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.888 0.112 0.000
M41 Scoliosis
0.886 0.114 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.885 0.115 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.885 0.115 0.000
I95.2 Hypotension due to drugs
0.884 0.116 0.000
O80-O84 Delivery
0.883 0.117 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.880 0.120 0.000
M65-M68 Disorders of synovium and tendon
0.877 0.123 0.000
G30-G32 Other degenerative diseases of the nervous system
0.875 0.125 0.000
M20-M25 Other joint disorders
0.872 0.128 0.000
S10-S19 Injuries to the neck
0.871 0.129 0.000
M46 Other inflammatory spondylopathies
0.868 0.132 0.000
I67 Other cerebrovascular diseases
0.867 0.133 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.865 0.135 0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.864 0.136 0.000
I05-I09 Chronic rheumatic heart diseases
0.864 0.136 0.000
K55 Vascular disorders of intestine
0.863 0.137 0.000
M13.9 Arthritis, unspecified
0.863 0.137 0.000
I60 Subarachnoid haemorrhage
0.861 0.139 0.000
M10 Gout
0.861 0.139 0.000
K62.0 Anal polyp
0.858 0.142 0.000
O26.8 Other specified pregnancy-related conditions
0.854 0.146 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.853 0.147 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.851 0.149 0.000
M25 Other joint disorders, not elsewhere classified
0.849 0.151 0.000
C51-C58 Malignant neoplasms of female genital organs
0.846 0.154 0.000
H90-H95 Other disorders of ear
0.845 0.155 0.000
M05 Seropositive rheumatoid arthritis
0.843 0.157 0.000
K62.7 Radiation proctitis
0.842 0.158 0.000
E21.3 Hyperparathyroidism, unspecified
0.842 0.158 0.000
M43.1 Spondylolisthesis
0.841 0.159 0.000
W00-W19 Falls
0.841 0.159 0.000
C25.0 Head of pancreas
0.840 0.160 0.000
M25.7 Osteophyte
0.839 0.161 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.837 0.163 0.000
S90-S99 Injuries to the ankle and foot
0.835 0.165 0.000
X60-X84 Intentional self-harm
0.834 0.166 0.000
T42.4 Benzodiazepines
0.832 0.168 0.000
G90-G99 Other disorders of the nervous system
0.830 0.169 0.000
X50-X57 Overexertion, travel and privation
0.830 0.170 0.000
S61.0 Open wound of finger(s) without damage to nail
0.830 0.170 0.000
W50-W64 Exposure to animate mechanical forces
0.829 0.171 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.829 0.171 0.000
K65-K67 Diseases of peritoneum
0.829 0.171 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.828 0.172 0.000
F60-F69 Disorders of adult personality and behaviour
0.825 0.174 0.000
M41.9 Scoliosis, unspecified
0.822 0.178 0.000
M86-M90 Other osteopathies
0.821 0.179 0.000
I67.8 Other specified cerebrovascular diseases
0.820 0.180 0.000
K55.2 Angiodysplasia of colon
0.818 0.182 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.817 0.183 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.817 0.183 0.000
E83 Disorders of mineral metabolism
0.817 0.183 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.815 0.185 0.000
M25.77 Osteophyte (Ankle and foot)
0.814 0.186 0.000
S60 Superficial injury of wrist and hand
0.814 0.186 0.000
O60-O75 Complications of labour and delivery
0.814 0.186 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.813 0.187 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.811 0.189 0.000
M80-M85 Disorders of bone density and structure
0.811 0.189 0.000
O03 Spontaneous abortion
0.811 0.189 0.000
O80 Single spontaneous delivery
0.810 0.190 0.000
Y57 Other and unspecified drugs and medicaments
0.809 0.191 0.000
E00-E07 Disorders of thyroid gland
0.809 0.191 0.000
E88 Other metabolic disorders
0.809 0.191 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.809 0.191 0.000
K63.2 Fistula of intestine
0.808 0.192 0.000
M06.3 Rheumatoid nodule
0.804 0.196 0.000
Y40 Systemic antibiotics
0.804 0.196 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.803 0.197 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.799 0.201 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.798 0.202 0.000
S70-S79 Injuries to the hip and thigh
0.798 0.202 0.000
S64 Injury of nerves at wrist and hand level
0.796 0.204 0.000
S80-S89 Injuries to the knee and lower leg
0.794 0.206 0.000
M43.0 Spondylolysis
0.794 0.206 0.000
F17.1 Harmful use
0.793 0.207 0.000
K63.1 Perforation of intestine (nontraumatic)
0.793 0.207 0.000
V40-V49 Car occupant injured in transport accident
0.790 0.210 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.789 0.211 0.000
M47.9 Spondylosis, unspecified
0.789 0.211 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.787 0.213 0.000
Y52 Agents primarily affecting the cardiovascular system
0.787 0.213 0.000
C25.9 Pancreas, unspecified
0.787 0.213 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.787 0.213 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.786 0.214 0.000
G51 Facial nerve disorders
0.786 0.214 0.000
E50-E64 Other nutritional deficiencies
0.785 0.215 0.000
C20 Malignant neoplasm of rectum
0.784 0.216 0.000
O80.0 Spontaneous vertex delivery
0.784 0.216 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.784 0.216 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.782 0.218 0.000
K63.3 Ulcer of intestine
0.782 0.218 0.000
S65 Injury of blood vessels at wrist and hand level
0.780 0.220 0.000
K70 Alcoholic liver disease
0.777 0.223 0.000
I95.8 Other hypotension
0.774 0.226 0.000
O30 Multiple gestation
0.774 0.226 0.000
G80 Infantile cerebral palsy
0.774 0.226 0.000
K76.6 Portal hypertension
0.772 0.228 0.000
M67 Other disorders of synovium and tendon
0.771 0.229 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.768 0.232 0.000
D45 Polycythaemia vera
0.767 0.233 0.000
K72 Hepatic failure, not elsewhere classified
0.766 0.234 0.000
W25 Contact with sharp glass
0.766 0.234 0.000
C21 Malignant neoplasm of anus and anal canal
0.764 0.236 0.000
W44 Foreign body entering into or through eye or natural orifice
0.762 0.238 0.000
K35-K38 Diseases of appendix
0.762 0.238 0.000
M43.17 Spondylolisthesis (Lumbosacral region)
0.762 0.238 0.000
H60-H62 Diseases of external ear
0.761 0.239 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.761 0.239 0.000
M10.9 Gout, unspecified
0.761 0.239 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.761 0.239 0.000
M13.98 Arthritis, unspecified (Other)
0.759 0.241 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.759 0.241 0.000
Y48 Anaesthetics and therapeutic gases
0.759 0.241 0.000
H73 Other disorders of tympanic membrane
0.757 0.243 0.000
M47.86 Other spondylosis (Lumbar region)
0.757 0.243 0.000
C18 Malignant neoplasm of colon
0.757 0.243 0.000
E40-E46 Malnutrition
0.757 0.243 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.755 0.245 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.754 0.246 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.753 0.247 0.000
O85-O92 Complications predominantly related to the puerperium
0.752 0.248 0.000
G70-G73 Diseases of myoneural junction and muscle
0.751 0.248 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.751 0.249 0.000
C53 Malignant neoplasm of cervix uteri
0.751 0.249 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.751 0.249 0.000
H72 Perforation of tympanic membrane
0.751 0.249 0.000
K76.8 Other specified diseases of liver
0.750 0.250 0.000
M06.0 Seronegative rheumatoid arthritis
0.749 0.251 0.000
K63.8 Other specified diseases of intestine
0.749 0.251 0.000
G51.0 Bell's palsy
0.747 0.253 0.000
O41 Other disorders of amniotic fluid and membranes
0.746 0.254 0.000
K62.3 Rectal prolapse
0.746 0.254 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.746 0.254 0.000
S40-S49 Injuries to the shoulder and upper arm
0.746 0.254 0.000
M25.74 Osteophyte (Hand)
0.746 0.254 0.000
E22 Hyperfunction of pituitary gland
0.745 0.255 0.000
K75 Other inflammatory liver diseases
0.745 0.255 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.741 0.259 0.000
E83.1 Disorders of iron metabolism
0.741 0.259 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.741 0.259 0.000
H74 Other disorders of middle ear and mastoid
0.738 0.262 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.738 0.262 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.738 0.262 0.000
M48 Other spondylopathies
0.738 0.262 0.000
V10-V19 Pedal cyclist injured in transport accident
0.737 0.263 0.000
G82 Paraplegia and tetraplegia
0.736 0.264 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.735 0.265 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.735 0.265 0.000
E85 Amyloidosis
0.735 0.265 0.000
M00-M03 Infectious arthropathies
0.734 0.265 0.000
F99-F99 Unspecified mental disorder
0.734 0.266 0.000
I25.5 Ischaemic cardiomyopathy
0.734 0.266 0.000
O02 Other abnormal products of conception
0.734 0.266 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.733 0.266 0.000
O40 Polyhydramnios
0.733 0.267 0.000
H93 Other disorders of ear, not elsewhere classified
0.733 0.267 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.733 0.267 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.732 0.268 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.732 0.268 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.731 0.269 0.000
E21.0 Primary hyperparathyroidism
0.731 0.269 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.731 0.269 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.731 0.269 0.000
Chapter X Diseases of the respiratory system
0.730 0.270 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.730 0.270 0.000
E03 Other hypothyroidism
0.730 0.270 0.000
Y40.8 Other systemic antibiotics
0.728 0.272 0.000
E34 Other endocrine disorders
0.728 0.272 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.727 0.273 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.726 0.273 0.000
F60 Specific personality disorders
0.726 0.274 0.000
W19 Unspecified fall
0.724 0.276 0.000
M13.94 Arthritis, unspecified (Hand)
0.724 0.276 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.724 0.276 0.000
O03.4 Incomplete, without complication
0.723 0.277 0.000
I22 Subsequent myocardial infarction
0.722 0.278 0.000
H80-H83 Diseases of inner ear
0.722 0.278 0.000
S61.7 Multiple open wounds of wrist and hand
0.721 0.279 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.721 0.279 0.000
T66-T78 Other and unspecified effects of external causes
0.720 0.280 0.000
I25.1 Atherosclerotic heart disease
0.720 0.280 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.720 0.280 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.719 0.281 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.718 0.282 0.000
O26.9 Pregnancy-related condition, unspecified
0.718 0.282 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.718 0.282 0.000
H66 Suppurative and unspecified otitis media
0.718 0.282 0.000
O20 Haemorrhage in early pregnancy
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M14 Arthropathies in other diseases classified elsewhere
0.717 0.283 0.000
M12 Other specific arthropathies
0.717 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.717 0.283 0.000
M08 Juvenile arthritis
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
M31 Other necrotising vasculopathies
0.716 0.283 0.000
I60.4 Subarachnoid haemorrhage from basilar artery
0.716 0.284 0.000
T33-T35 Frostbite
0.715 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.285 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.715 0.285 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.715 0.285 0.000
T00-T07 Injuries involving multiple body regions
0.715 0.285 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.715 0.285 0.000
M06.8 Other specified rheumatoid arthritis
0.715 0.285 0.000
M06.4 Inflammatory polyarthropathy
0.715 0.285 0.000
M06.2 Rheumatoid bursitis
0.715 0.285 0.000
M06.1 Adult-onset Still's disease
0.715 0.285 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.714 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.714 0.285 0.000
Y10-Y34 Event of undetermined intent
0.714 0.285 0.000
Y00-Y09 Assault
0.714 0.285 0.000
X85-X99 Assault
0.714 0.285 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.714 0.285 0.000
X30-X39 Exposure to forces of nature
0.714 0.285 0.000
X20-X29 Contact with venomous animals and plants
0.714 0.285 0.000
X10-X19 Contact with heat and hot substances
0.714 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.714 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.714 0.285 0.000
W75-W84 Other accidental threats to breathing
0.714 0.285 0.000
W65-W74 Accidental drowning and submersion
0.714 0.285 0.000
V98-V99 Other and unspecified transport accidents
0.714 0.285 0.000
V95-V97 Air and space transport accidents
0.714 0.285 0.000
V90-V94 Water transport accidents
0.714 0.285 0.000
V80-V89 Other land transport accidents
0.714 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.714 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.714 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.714 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.714 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.714 0.285 0.000
M24 Other specific joint derangements
0.714 0.285 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.713 0.287 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.713 0.287 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.713 0.287 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.713 0.287 0.000
K50 Crohn's disease [regional enteritis]
0.713 0.287 0.000
M91-M94 Chondropathies
0.712 0.288 0.000
O44 Placenta praevia
0.711 0.289 0.000
G93 Other disorders of brain
0.711 0.289 0.000
W55 Bitten or struck by other mammals
0.710 0.290 0.000
C64-C68 Malignant neoplasms of urinary tract
0.709 0.291 0.000
I23 Certain current complications following acute myocardial infarction
0.709 0.291 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.708 0.292 0.000
M11 Other crystal arthropathies
0.708 0.292 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.707 0.293 0.000
K62.2 Anal prolapse
0.706 0.293 0.000
I62 Other nontraumatic intracranial haemorrhage
0.706 0.294 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.706 0.294 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.704 0.295 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.704 0.295 0.000
I99 Other and unspecified disorders of circulatory system
0.703 0.297 0.000
M43.02 Spondylolysis (Cervical region)
0.703 0.297 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.703 0.297 0.000
I25.3 Aneurysm of heart
0.702 0.298 0.000
S68 Traumatic amputation of wrist and hand
0.702 0.298 0.000
H70 Mastoiditis and related conditions
0.701 0.298 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.701 0.299 0.000
M49 Spondylopathies in diseases classified elsewhere
0.701 0.299 0.000
S12 Fracture of neck
0.701 0.299 0.000
K76.9 Liver disease, unspecified
0.701 0.299 0.000
O21 Excessive vomiting in pregnancy
0.700 0.300 0.000
M42 Spinal osteochondrosis
0.699 0.301 0.000
M40 Kyphosis and lordosis
0.699 0.301 0.000
I05 Rheumatic mitral valve diseases
0.699 0.301 0.000
G12 Spinal muscular atrophy and related syndromes
0.698 0.302 0.000
M10.99 Gout, unspecified (Site unspecified)
0.698 0.302 0.000
G80.9 Infantile cerebral palsy, unspecified
0.698 0.302 0.000
F10.2 Dependence syndrome
0.698 0.302 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.697 0.303 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.697 0.303 0.000
O47 False labour
0.697 0.303 0.000
S67 Crushing injury of wrist and hand
0.696 0.304 0.000
I95.0 Idiopathic hypotension
0.696 0.304 0.000
O43 Placental disorders
0.695 0.305 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.695 0.305 0.000
I25.6 Silent myocardial ischaemia
0.694 0.306 0.000
I25.4 Coronary artery aneurysm
0.694 0.306 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.694 0.306 0.000
W22 Striking against or struck by other objects
0.693 0.307 0.000
Y57.9 Drug or medicament, unspecified
0.693 0.307 0.000
G20-G26 Extrapyramidal and movement disorders
0.692 0.308 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.692 0.308 0.000
F80-F89 Disorders of psychological development
0.692 0.308 0.000
F70-F79 Mental retardation
0.692 0.308 0.000
M21 Other acquired deformities of limbs
0.692 0.308 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.692 0.308 0.000
I61 Intracerebral haemorrhage
0.691 0.308 0.000
K83 Other diseases of biliary tract
0.691 0.309 0.000
I24.1 Dressler's syndrome
0.690 0.309 0.000
I25.2 Old myocardial infarction
0.690 0.310 0.000
K77 Liver disorders in diseases classified elsewhere
0.690 0.310 0.000
K73 Chronic hepatitis, not elsewhere classified
0.690 0.310 0.000
K71 Toxic liver disease
0.690 0.310 0.000
C15 Malignant neoplasm of oesophagus
0.690 0.310 0.000
I08 Multiple valve diseases
0.690 0.310 0.000
E83.5 Disorders of calcium metabolism
0.690 0.310 0.000
M47.1 Other spondylosis with myelopathy
0.689 0.311 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.688 0.312 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.687 0.313 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.686 0.314 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.685 0.315 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.685 0.315 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.684 0.315 0.000
S80 Superficial injury of lower leg
0.684 0.316 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.684 0.316 0.000
K52.3 Indeterminate colitis
0.684 0.316 0.000
F20 Schizophrenia
0.683 0.317 0.000
K61 Abscess of anal and rectal regions
0.683 0.317 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.683 0.317 0.000
K52.0 Gastro-enteritis and colitis due to radiation
0.683 0.317 0.000
O45 Premature separation of placenta [abruptio placentae]
0.682 0.318 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.682 0.318 0.000
O33 Maternal care for known or suspected disproportion
0.682 0.318 0.000
O31 Complications specific to multiple gestation
0.682 0.318 0.000
O04 Medical abortion
0.682 0.318 0.000
Y59 Other and unspecified vaccines and biological substances
0.681 0.319 0.000
Y58 Bacterial vaccines
0.681 0.319 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.681 0.319 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.681 0.319 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.681 0.319 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.681 0.319 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.681 0.319 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.681 0.319 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.681 0.319 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.681 0.319 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.681 0.319 0.000
S91 Open wound of ankle and foot
0.680 0.320 0.000
M25.8 Other specified joint disorders
0.679 0.321 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.678 0.322 0.000
G30 Alzheimer's disease
0.678 0.322 0.000
M43.19 Spondylolisthesis (Site unspecified)
0.678 0.322 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.677 0.322 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.677 0.322 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.677 0.322 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.677 0.322 0.000
T36 Poisoning by systemic antibiotics
0.677 0.322 0.000
O29 Complications of anaesthesia during pregnancy
0.677 0.323 0.000
O28 Abnormal findings on antenatal screening of mother
0.677 0.323 0.000
O22 Venous complications in pregnancy
0.677 0.323 0.000
O25 Malnutrition in pregnancy
0.677 0.323 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.676 0.324 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.676 0.324 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.676 0.324 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.676 0.324 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.676 0.324 0.000
M66 Spontaneous rupture of synovium and tendon
0.675 0.325 0.000
V20-V29 Motorcycle rider injured in transport accident
0.675 0.325 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.675 0.325 0.000
M47.2 Other spondylosis with radiculopathy
0.674 0.325 0.000
E03.9 Hypothyroidism, unspecified
0.673 0.327 0.000
S60.9 Superficial injury of wrist and hand, unspecified
0.673 0.327 0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.672 0.328 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.672 0.328 0.000
M25.76 Osteophyte (Lower leg)
0.671 0.329 0.000
M86 Osteomyelitis
0.670 0.330 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.670 0.330 0.000
K65 Peritonitis
0.670 0.330 0.000
M67.8 Other specified disorders of synovium and tendon
0.670 0.330 0.000
W25.9 Unspecified place
0.669 0.331 0.000
O48 Prolonged pregnancy
0.669 0.331 0.000
S50-S59 Injuries to the elbow and forearm
0.669 0.331 0.000
T91 Sequelae of injuries of neck and trunk
0.668 0.332 0.000
X50 Overexertion and strenuous or repetitive movements
0.668 0.332 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.667 0.333 0.000
H90 Conductive and sensorineural hearing loss
0.667 0.333 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.666 0.334 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.666 0.334 0.000
E32 Diseases of thymus
0.666 0.334 0.000
E31 Polyglandular dysfunction
0.666 0.334 0.000
E30 Disorders of puberty, not elsewhere classified
0.666 0.334 0.000
E29 Testicular dysfunction
0.666 0.334 0.000
E26 Hyperaldosteronism
0.666 0.334 0.000
E25 Adrenogenital disorders
0.666 0.334 0.000
E24 Cushing's syndrome
0.666 0.334 0.000
E20 Hypoparathyroidism
0.666 0.334 0.000
M06.34 Rheumatoid nodule (Hand)
0.666 0.334 0.000
O23 Infections of genito-urinary tract in pregnancy
0.665 0.335 0.000
K58 Irritable bowel syndrome
0.665 0.335 0.000
E84 Cystic fibrosis
0.665 0.335 0.000
E79 Disorders of purine and pyrimidine metabolism
0.665 0.335 0.000
E77 Disorders of glycoprotein metabolism
0.665 0.335 0.000
E76 Disorders of glycosaminoglycan metabolism
0.665 0.335 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.665 0.335 0.000
E74 Other disorders of carbohydrate metabolism
0.665 0.335 0.000
E73 Lactose intolerance
0.665 0.335 0.000
E72 Other disorders of amino-acid metabolism
0.665 0.335 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.665 0.335 0.000
E70 Disorders of aromatic amino-acid metabolism
0.665 0.335 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.665 0.335 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.664 0.336 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.664 0.336 0.000
C17 Malignant neoplasm of small intestine
0.664 0.336 0.000
C23 Malignant neoplasm of gallbladder
0.664 0.336 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.664 0.336 0.000
S19 Other and unspecified injuries of neck
0.663 0.336 0.000
W44.0 Home
0.663 0.337 0.000
I69 Sequelae of cerebrovascular disease
0.663 0.337 0.000
K63.4 Enteroptosis
0.662 0.338 0.000
K63.0 Abscess of intestine
0.662 0.338 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.662 0.338 0.000
C16 Malignant neoplasm of stomach
0.662 0.338 0.000
M43.9 Deforming dorsopathy, unspecified
0.660 0.340 0.000
M43.8 Other specified deforming dorsopathies
0.660 0.340 0.000
M43.6 Torticollis
0.660 0.340 0.000
M43.5 Other recurrent vertebral subluxation
0.660 0.340 0.000
M43.4 Other recurrent atlantoaxial subluxation
0.660 0.340 0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy
0.660 0.340 0.000
M43.2 Other fusion of spine
0.660 0.340 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.660 0.340 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.660 0.340 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.660 0.340 0.000
I07 Rheumatic tricuspid valve diseases
0.660 0.340 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.659 0.341 0.000
O32.1 Maternal care for breech presentation
0.658 0.342 0.000
X51 Travel and motion
0.658 0.342 0.000
M13.8 Other specified arthritis
0.658 0.342 0.000
M13.1 Monoarthritis, not elsewhere classified
0.658 0.342 0.000
M81 Osteoporosis without pathological fracture
0.657 0.343 0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)
0.657 0.343 0.000
Y45.0 Opioids and related analgesics
0.657 0.343 0.000
G51.3 Clonic hemifacial spasm
0.657 0.343 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.656 0.343 0.000
K76.7 Hepatorenal syndrome
0.656 0.344 0.000
K76.5 Hepatic veno-occlusive disease
0.656 0.344 0.000
K76.4 Peliosis hepatis
0.656 0.344 0.000
K76.3 Infarction of liver
0.656 0.344 0.000
K76.2 Central haemorrhagic necrosis of liver
0.656 0.344 0.000
K76.1 Chronic passive congestion of liver
0.656 0.344 0.000
X78 Intentional self-harm by sharp object
0.654 0.345 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.654 0.346 0.000
S62 Fracture at wrist and hand level
0.653 0.347 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.653 0.347 0.000
O07 Failed attempted abortion
0.653 0.347 0.000
O06 Unspecified abortion
0.653 0.347 0.000
O05 Other abortion
0.653 0.347 0.000
O01 Hydatidiform mole
0.653 0.347 0.000
H93.1 Tinnitus
0.653 0.347 0.000
K70.3 Alcoholic cirrhosis of liver
0.653 0.347 0.000
O24 Diabetes mellitus in pregnancy
0.652 0.348 0.000
T92 Sequelae of injuries of upper limb
0.652 0.348 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.652 0.348 0.000
H68 Eustachian salpingitis and obstruction
0.652 0.348 0.000
H67 Otitis media in diseases classified elsewhere
0.652 0.348 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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