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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs73200436
log Bayes Factor = 2.81861
Chromosome 12   position 110,062,693  (GRCh37) Explore rs73200436 on Ensembl!
Variant rs73200436 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
0.998 0.002 0.000
Chapter VII Diseases of the eye and adnexa
0.997 0.003 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.990 0.010 0.000
H53-H54 Visual disturbances and blindness
0.985 0.015 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.980 0.020 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.977 0.023 0.000
Chapter I Certain infectious and parasitic diseases
0.967 0.033 0.000
M65-M68 Disorders of synovium and tendon
0.962 0.038 0.000
M50-M54 Other dorsopathies
0.956 0.044 0.000
H04 Disorders of lachrymal system
0.955 0.045 0.000
H54 Blindness and low vision
0.955 0.045 0.000
Chapter II Neoplasms
0.946 0.054 0.000
M65 Synovitis and tenosynovitis
0.942 0.058 0.000
A00-A09 Intestinal infectious diseases
0.933 0.067 0.000
M54 Dorsalgia
0.926 0.074 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.909 0.091 0.000
H53 Visual disturbances
0.904 0.096 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.904 0.096 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.901 0.099 0.000
C64-C68 Malignant neoplasms of urinary tract
0.900 0.100 0.000
H54.7 Unspecified visual loss
0.895 0.105 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.893 0.107 0.000
B95-B98 Bacterial, viral and other infectious agents
0.889 0.111 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.888 0.112 0.000
H04.1 Other disorders of lachrymal gland
0.887 0.113 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.883 0.117 0.000
M54.5 Low back pain
0.875 0.125 0.000
R50-R69 General symptoms and signs
0.872 0.128 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.866 0.134 0.000
Chapter VI Diseases of the nervous system
0.866 0.134 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.866 0.134 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.861 0.139 0.000
L03 Cellulitis
0.856 0.144 0.000
S00-S09 Injuries to the head
0.854 0.146 0.000
Chapter VIII Diseases of the ear and mastoid process
0.850 0.150 0.000
M80-M85 Disorders of bone density and structure
0.848 0.152 0.000
H54.0 Blindness, both eyes
0.841 0.159 0.000
Chapter XI Diseases of the digestive system
0.838 0.162 0.000
M65.3 Trigger finger
0.832 0.167 0.000
H02 Other disorders of eyelid
0.825 0.175 0.000
M54.9 Dorsalgia, unspecified
0.825 0.175 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.824 0.176 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.823 0.177 0.000
K70-K77 Diseases of liver
0.822 0.178 0.000
H04.2 Epiphora
0.817 0.183 0.000
R47-R49 Symptoms and signs involving speech and voice
0.815 0.185 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.814 0.186 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.814 0.186 0.000
S80-S89 Injuries to the knee and lower leg
0.813 0.187 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.812 0.188 0.000
D00-D09 In situ neoplasms
0.810 0.190 0.000
S32 Fracture of lumbar spine and pelvis
0.809 0.191 0.000
S70-S79 Injuries to the hip and thigh
0.809 0.191 0.000
R69 Unknown and unspecified causes of morbidity
0.807 0.193 0.000
R60 Oedema, not elsewhere classified
0.807 0.193 0.000
C67 Malignant neoplasm of bladder
0.804 0.196 0.000
M54.56 Low back pain (Lumbar region)
0.802 0.198 0.000
S90-S99 Injuries to the ankle and foot
0.800 0.200 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.799 0.201 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.797 0.203 0.000
G90-G99 Other disorders of the nervous system
0.793 0.207 0.000
S01 Open wound of head
0.790 0.210 0.000
H04.9 Disorder of lachrymal system, unspecified
0.787 0.213 0.000
H53.0 Amblyopia ex anopsia
0.786 0.214 0.000
L20-L30 Dermatitis and eczema
0.781 0.219 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.780 0.219 0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.780 0.220 0.000
H60-H62 Diseases of external ear
0.777 0.223 0.000
M45-M49 Spondylopathies
0.777 0.223 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.776 0.224 0.000
R47 Speech disturbances, not elsewhere classified
0.773 0.227 0.000
H55-H59 Other disorders of eye and adnexa
0.772 0.228 0.000
K35-K38 Diseases of appendix
0.769 0.231 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.768 0.231 0.000
A08 Viral and other specified intestinal infections
0.765 0.235 0.000
A02 Other Salmonella infections
0.763 0.237 0.000
L03.1 Cellulitis of other parts of limb
0.763 0.237 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.763 0.237 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.762 0.237 0.000
R51 Headache
0.762 0.238 0.000
R26 Abnormalities of gait and mobility
0.761 0.239 0.000
R56 Convulsions, not elsewhere classified
0.761 0.239 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.759 0.241 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.758 0.242 0.000
C15-C26 Malignant neoplasms of digestive organs
0.756 0.244 0.000
S10-S19 Injuries to the neck
0.755 0.245 0.000
R60.0 Localised oedema
0.754 0.246 0.000
M65.34 Trigger finger-Hand
0.754 0.246 0.000
C51-C58 Malignant neoplasms of female genital organs
0.753 0.247 0.000
H02.8 Other specified disorders of eyelid
0.753 0.247 0.000
S20-S29 Injuries to the thorax
0.751 0.249 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.748 0.252 0.000
K76 Other diseases of liver
0.748 0.252 0.000
L03.3 Cellulitis of trunk
0.747 0.253 0.000
M51 Other intervertebral disk disorders
0.743 0.257 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.742 0.258 0.000
S01.0 Open wound of scalp
0.741 0.258 0.000
R29.6 Tendency to fall, not elsewhere classified
0.741 0.259 0.000
H05 Disorders of orbit
0.741 0.259 0.000
C67.9 Bladder, unspecified
0.740 0.260 0.000
L08 Other local infections of skin and subcutaneous tissue
0.739 0.261 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.738 0.262 0.000
H53.4 Visual field defects
0.735 0.265 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.734 0.266 0.000
H18 Other disorders of cornea
0.734 0.266 0.000
S31 Open wound of abdomen, lower back and pelvis
0.733 0.267 0.000
M84 Disorders of continuity of bone
0.732 0.268 0.000
Chapter XXII Codes for special purposes
0.729 0.271 0.000
H54.4 Blindness, one eye
0.725 0.275 0.000
H01 Other inflammation of eyelid
0.725 0.275 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.725 0.275 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.723 0.277 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.720 0.280 0.000
R21 Rash and other nonspecific skin eruption
0.718 0.282 0.000
S32.5 Fracture of pubis
0.717 0.283 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.716 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.715 0.285 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.715 0.285 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.714 0.286 0.000
H02.9 Disorder of eyelid, unspecified
0.714 0.286 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.713 0.287 0.000
H10-H13 Disorders of conjunctiva
0.712 0.288 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.712 0.288 0.000
M91-M94 Chondropathies
0.710 0.290 0.000
M60-M63 Disorders of muscles
0.710 0.290 0.000
M00-M03 Infectious arthropathies
0.710 0.290 0.000
K72 Hepatic failure, not elsewhere classified
0.709 0.291 0.000
B35-B49 Mycoses
0.709 0.291 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.705 0.295 0.000
H53.8 Other visual disturbances
0.704 0.296 0.000
T79-T79 Certain early complications of trauma
0.702 0.298 0.000
T33-T35 Frostbite
0.702 0.298 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.702 0.298 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.702 0.298 0.000
T00-T07 Injuries involving multiple body regions
0.702 0.298 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.701 0.299 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.701 0.299 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.700 0.299 0.000
K76.8 Other specified diseases of liver
0.700 0.300 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.698 0.302 0.000
R63 Symptoms and signs concerning food and fluid intake
0.694 0.306 0.000
A04 Other bacterial intestinal infections
0.693 0.307 0.000
B99-B99 Other infectious diseases
0.693 0.307 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.693 0.307 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.693 0.307 0.000
B65-B83 Helminthiases
0.693 0.307 0.000
B50-B64 Protozoal diseases
0.693 0.307 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.693 0.307 0.000
B15-B19 Viral hepatitis
0.693 0.307 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.693 0.307 0.000
A80-A89 Viral infections of the central nervous system
0.693 0.307 0.000
A75-A79 Rickettsioses
0.693 0.307 0.000
A70-A74 Other diseases caused by chlamydiae
0.693 0.307 0.000
A65-A69 Other spirochaetal diseases
0.693 0.307 0.000
A20-A28 Certain zoonotic bacterial diseases
0.693 0.307 0.000
A15-A19 Tuberculosis
0.693 0.307 0.000
M54.4 Lumbago with sciatica
0.691 0.309 0.000
M20-M25 Other joint disorders
0.690 0.310 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.689 0.310 0.000
M66 Spontaneous rupture of synovium and tendon
0.689 0.310 0.000
M54.3 Sciatica
0.687 0.313 0.000
M53 Other dorsopathies, not elsewhere classified
0.686 0.314 0.000
H04.8 Other disorders of lachrymal system
0.685 0.315 0.000
H04.6 Other changes in lachrymal passages
0.685 0.315 0.000
H04.4 Chronic inflammation of lachrymal passages
0.685 0.315 0.000
H04.3 Acute and unspecified inflammation of lachrymal passages
0.685 0.315 0.000
H04.0 Dacryoadenitis
0.685 0.315 0.000
M50 Cervical disk disorders
0.685 0.315 0.000
H54.9 Unspecified visual impairment (binocular)
0.685 0.315 0.000
H54.6 Unqualified visual loss, one eye
0.685 0.315 0.000
H54.5 Low vision, one eye
0.685 0.315 0.000
H54.3 Unqualified visual loss, both eyes
0.685 0.315 0.000
H54.2 Low vision, both eyes
0.685 0.315 0.000
H54.1 Blindness, one eye, low vision, other eye
0.685 0.315 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.683 0.317 0.000
H21 Other disorders of iris and ciliary body
0.682 0.318 0.000
R56.8 Other and unspecified convulsions
0.682 0.318 0.000
H61 Other disorders of external ear
0.682 0.318 0.000
M86-M90 Other osteopathies
0.682 0.318 0.000
H90-H95 Other disorders of ear
0.681 0.319 0.000
M67 Other disorders of synovium and tendon
0.680 0.320 0.000
S82 Fracture of lower leg, including ankle
0.680 0.320 0.000
L30 Other dermatitis
0.679 0.321 0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.679 0.321 0.000
S01.9 Open wound of head, part unspecified
0.679 0.321 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.678 0.321 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.678 0.321 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.678 0.322 0.000
D05 Carcinoma in situ of breast
0.678 0.322 0.000
T86 Failure and rejection of transplanted organs and tissues
0.677 0.323 0.000
R23 Other skin changes
0.676 0.324 0.000
L03.2 Cellulitis of face
0.676 0.324 0.000
R47.8 Other and unspecified speech disturbances
0.676 0.324 0.000
M65.8 Other synovitis and tenosynovitis
0.676 0.324 0.000
M65.2 Calcific tendinitis
0.676 0.324 0.000
M65.1 Other infective (teno)synovitis
0.676 0.324 0.000
M65.0 Abscess of tendon sheath
0.676 0.324 0.000
T82.1 Mechanical complication of cardiac electronic device
0.675 0.325 0.000
H53.2 Diplopia
0.675 0.325 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.674 0.326 0.000
D04 Carcinoma in situ of skin
0.673 0.327 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.673 0.327 0.000
H43-H45 Disorders of vitreous body and globe
0.673 0.327 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.672 0.327 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.671 0.329 0.000
R59 Enlarged lymph nodes
0.671 0.329 0.000
C16 Malignant neoplasm of stomach
0.671 0.329 0.000
S32.4 Fracture of acetabulum
0.670 0.330 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.670 0.330 0.000
L03.9 Cellulitis, unspecified
0.670 0.330 0.000
K70 Alcoholic liver disease
0.670 0.330 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.670 0.330 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.670 0.330 0.000
A07 Other protozoal intestinal diseases
0.669 0.331 0.000
A06 Amoebiasis
0.669 0.331 0.000
A05 Other bacterial foodborne intoxications
0.669 0.331 0.000
A03 Shigellosis
0.669 0.331 0.000
A01 Typhoid and paratyphoid fevers
0.669 0.331 0.000
A00 Cholera
0.669 0.331 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.669 0.331 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.668 0.332 0.000
S06 Intracranial injury
0.668 0.332 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.667 0.332 0.000
Chapter XXI Factors influencing health status and contact with health services
0.667 0.333 0.000
S02 Fracture of skull and facial bones
0.665 0.335 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.665 0.335 0.000
M54.8 Other dorsalgia
0.664 0.336 0.000
M54.6 Pain in thoracic spine
0.664 0.336 0.000
M54.0 Panniculitis affecting regions of neck and back
0.664 0.336 0.000
M85 Other disorders of bone density and structure
0.664 0.336 0.000
K21 Gastro-oesophageal reflux disease
0.664 0.336 0.000
G62 Other polyneuropathies
0.663 0.337 0.000
R68 Other general symptoms and signs
0.663 0.337 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.663 0.337 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.662 0.337 0.000
M05-M14 Inflammatory polyarthropathies
0.661 0.339 0.000
H02.3 Blepharochalasis
0.660 0.340 0.000
S40-S49 Injuries to the shoulder and upper arm
0.660 0.340 0.000
H60 Otitis externa
0.657 0.343 0.000
K75 Other inflammatory liver diseases
0.655 0.345 0.000
L40-L45 Papulosquamous disorders
0.655 0.345 0.000
R47.0 Dysphasia and aphasia
0.652 0.348 0.000
S81 Open wound of lower leg
0.652 0.348 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.652 0.348 0.000
G30-G32 Other degenerative diseases of the nervous system
0.651 0.349 0.000
H53.9 Visual disturbance, unspecified
0.651 0.349 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.651 0.349 0.000
R47.1 Dysarthria and anarthria
0.651 0.349 0.000
S32.50 Fracture of pubis (closed)
0.651 0.349 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.651 0.349 0.000
K37 Unspecified appendicitis
0.651 0.349 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.649 0.351 0.000
H53.6 Night blindness
0.648 0.352 0.000
H53.5 Colour vision deficiencies
0.648 0.352 0.000
H53.3 Other disorders of binocular vision
0.648 0.352 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.648 0.352 0.000
S37 Injury of urinary and pelvic organs
0.648 0.352 0.000
S36 Injury of intra-abdominal organs
0.648 0.352 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.648 0.352 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.648 0.352 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.648 0.352 0.000
M54.2 Cervicalgia
0.648 0.352 0.000
M40-M43 Deforming dorsopathies
0.647 0.353 0.000
M48 Other spondylopathies
0.647 0.353 0.000
S72 Fracture of femur
0.646 0.354 0.000
L10-L14 Bullous disorders
0.646 0.354 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.645 0.355 0.000
C66 Malignant neoplasm of ureter
0.645 0.355 0.000
C65 Malignant neoplasm of renal pelvis
0.645 0.355 0.000
G91 Hydrocephalus
0.645 0.355 0.000
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin
0.644 0.355 0.000
S92 Fracture of foot, except ankle
0.644 0.356 0.000
A08.1 Acute gastro-enteropathy due to Norwalk agent
0.643 0.357 0.000
S70 Superficial injury of hip and thigh
0.642 0.358 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.642 0.358 0.000
A02.0 Salmonella gastro-enteritis
0.642 0.358 0.000
H57 Other disorders of eye and adnexa
0.641 0.358 0.000
K21.9 Gastro-oesophageal reflux disease without oesophagitis
0.641 0.359 0.000
C71 Malignant neoplasm of brain
0.641 0.359 0.000
T66-T78 Other and unspecified effects of external causes
0.641 0.359 0.000
H40-H42 Glaucoma
0.641 0.359 0.000
K73 Chronic hepatitis, not elsewhere classified
0.640 0.360 0.000
H49 Paralytic strabismus
0.640 0.360 0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)
0.640 0.360 0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)
0.640 0.360 0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.640 0.360 0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.640 0.360 0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.640 0.360 0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.640 0.360 0.000
G93 Other disorders of brain
0.639 0.360 0.000
H52 Disorders of refraction and accommodation
0.639 0.361 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.637 0.363 0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)
0.637 0.363 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.637 0.363 0.000
H16 Keratitis
0.637 0.363 0.000
L04 Acute lymphadenitis
0.636 0.364 0.000
L01 Impetigo
0.636 0.364 0.000
L00 Staphylococcal scalded skin syndrome
0.636 0.364 0.000
K35 Acute appendicitis
0.634 0.366 0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.634 0.366 0.000
T87 Complications peculiar to reattachment and amputation
0.633 0.367 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.633 0.367 0.000
H53.1 Subjective visual disturbances
0.632 0.368 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.631 0.369 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.631 0.369 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.631 0.369 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.629 0.371 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.628 0.372 0.000
S01.2 Open wound of nose
0.628 0.372 0.000
B25-B34 Other viral diseases
0.628 0.372 0.000
H18.4 Corneal degeneration
0.627 0.373 0.000
K72.9 Hepatic failure, unspecified
0.627 0.373 0.000
M54.55 Low back pain (Thoracolumbar region)
0.627 0.373 0.000
M54.54 Low back pain-Thoracic
0.627 0.373 0.000
M54.53 Low back pain-Cervicothoracic
0.627 0.373 0.000
M54.52 Low back pain-Cervical
0.627 0.373 0.000
M54.51 Low back pain-Occipit-atl-axl
0.627 0.373 0.000
M54.50 Low back pain (Multiple sites in spine)
0.627 0.373 0.000
K74 Fibrosis and cirrhosis of liver
0.626 0.374 0.000
L05 Pilonidal cyst
0.626 0.374 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.625 0.375 0.000
R62 Lack of expected normal physiological development
0.625 0.375 0.000
R57 Shock, not elsewhere classified
0.625 0.375 0.000
R64 Cachexia
0.625 0.375 0.000
R58 Haemorrhage, not elsewhere classified
0.625 0.375 0.000
S60-S69 Injuries to the wrist and hand
0.624 0.376 0.000
C53 Malignant neoplasm of cervix uteri
0.624 0.376 0.000
R63.4 Abnormal weight loss
0.624 0.376 0.000
Chapter XX External causes of morbidity and mortality
0.624 0.376 0.000
H50 Other strabismus
0.623 0.377 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.623 0.377 0.000
K38 Other diseases of appendix
0.622 0.378 0.000
Z02 Examination and encounter for administrative purposes
0.622 0.378 0.000
G95 Other diseases of spinal cord
0.621 0.379 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.621 0.379 0.000
H20 Iridocyclitis
0.621 0.379 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.621 0.379 0.000
H17 Corneal scars and opacities
0.621 0.379 0.000
H15 Disorders of sclera
0.621 0.379 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.621 0.379 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.621 0.379 0.000
L03.0 Cellulitis of finger and toe
0.620 0.380 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.620 0.380 0.000
G70-G73 Diseases of myoneural junction and muscle
0.618 0.382 0.000
Z13 Special screening examination for other diseases and disorders
0.617 0.383 0.000
M25 Other joint disorders, not elsewhere classified
0.617 0.383 0.000
L03.8 Cellulitis of other sites
0.613 0.386 0.000
R53 Malaise and fatigue
0.613 0.387 0.000
S08 Traumatic amputation of part of head
0.612 0.388 0.000
S07 Crushing injury of head
0.612 0.388 0.000
S05 Injury of eye and orbit
0.612 0.388 0.000
S04 Injury of cranial nerves
0.612 0.388 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.612 0.388 0.000
S90 Superficial injury of ankle and foot
0.612 0.388 0.000
T82.3 Mechanical complication of other vascular grafts
0.612 0.388 0.000
M54.59 Low back pain (Site unspecified)
0.611 0.389 0.000
S31.1 Open wound of abdominal wall
0.610 0.389 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.610 0.390 0.000
K22 Other diseases of oesophagus
0.609 0.391 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.609 0.391 0.000
M80 Osteoporosis with pathological fracture
0.609 0.391 0.000
M83 Adult osteomalacia
0.608 0.392 0.000
M82 Osteoporosis in diseases classified elsewhere
0.608 0.392 0.000
L30.9 Dermatitis, unspecified
0.607 0.393 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.606 0.394 0.000
H90 Conductive and sensorineural hearing loss
0.604 0.396 0.000
M54.1 Radiculopathy
0.604 0.396 0.000
R60.9 Oedema, unspecified
0.603 0.397 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.602 0.397 0.000
Z02.8 Other examinations for administrative purposes
0.601 0.399 0.000
S82.4 Fracture of fibula alone
0.600 0.400 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.599 0.401 0.000
M65.39 Trigger finger-Site unspec
0.597 0.403 0.000
M65.38 Trigger finger-Other
0.597 0.403 0.000
M65.37 Trigger finger-Ankle/foot
0.597 0.403 0.000
M65.36 Trigger finger-Lower leg
0.597 0.403 0.000
M65.35 Trigger finger-Pelvic/thigh
0.597 0.403 0.000
M65.33 Trigger finger-Forearm
0.597 0.403 0.000
M65.32 Trigger finger-Upper arm
0.597 0.403 0.000
M65.31 Trigger finger-Shldr region
0.597 0.403 0.000
M65.30 Trigger finger-Mult sites
0.597 0.403 0.000
C18 Malignant neoplasm of colon
0.596 0.404 0.000
R27 Other lack of coordination
0.596 0.404 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.594 0.406 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.594 0.406 0.000
S12 Fracture of neck
0.593 0.406 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.593 0.407 0.000
H02.7 Other degenerative disorders of eyelid and periocular area
0.592 0.408 0.000
H02.2 Lagophthalmos
0.592 0.408 0.000
C81 Hodgkin's disease
0.592 0.408 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.592 0.408 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.592 0.408 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.592 0.408 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.592 0.408 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.592 0.408 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.592 0.408 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.592 0.408 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.591 0.409 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.591 0.409 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.591 0.409 0.000
H51 Other disorders of binocular movement
0.590 0.410 0.000
K77 Liver disorders in diseases classified elsewhere
0.590 0.410 0.000
K71 Toxic liver disease
0.590 0.410 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.590 0.410 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.589 0.411 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.589 0.411 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.589 0.411 0.000
L29 Pruritus
0.588 0.412 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.587 0.413 0.000
H02.0 Entropion and trichiasis of eyelid
0.586 0.414 0.000
C01 Malignant neoplasm of base of tongue
0.586 0.414 0.000
K29 Gastritis and duodenitis
0.585 0.415 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.584 0.416 0.000
M25.7 Osteophyte
0.584 0.416 0.000
S89 Other and unspecified injuries of lower leg
0.583 0.417 0.000
S88 Traumatic amputation of lower leg
0.583 0.417 0.000
S87 Crushing injury of lower leg
0.583 0.417 0.000
S86 Injury of muscle and tendon at lower leg level
0.583 0.417 0.000
S85 Injury of blood vessels at lower leg level
0.583 0.417 0.000
S84 Injury of nerves at lower leg level
0.583 0.417 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.583 0.417 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.583 0.417 0.000
G96 Other disorders of central nervous system
0.582 0.418 0.000
S27 Injury of other and unspecified intrathoracic organs
0.581 0.419 0.000
R22.9 Localised swelling, mass and lump, unspecified
0.581 0.419 0.000
D09 Carcinoma in situ of other and unspecified sites
0.581 0.419 0.000
D03 Melanoma in situ
0.581 0.419 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.581 0.419 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.581 0.419 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.581 0.419 0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis
0.580 0.420 0.000
S32.7 Multiple fractures of lumbar spine and pelvis
0.580 0.420 0.000
S32.3 Fracture of ilium
0.580 0.420 0.000
S32.2 Fracture of coccyx
0.580 0.420 0.000
S32.1 Fracture of sacrum
0.580 0.420 0.000
S78 Traumatic amputation of hip and thigh
0.580 0.420 0.000
S77 Crushing injury of hip and thigh
0.580 0.420 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.580 0.420 0.000
S75 Injury of blood vessels at hip and thigh level
0.580 0.420 0.000
S74 Injury of nerves at hip and thigh level
0.580 0.420 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.580 0.420 0.000
S71 Open wound of hip and thigh
0.580 0.420 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.580 0.420 0.000
R59.1 Generalised enlarged lymph nodes
0.579 0.421 0.000
H61.0 Perichondritis of external ear
0.579 0.421 0.000
T81 Complications of procedures, not elsewhere classified
0.579 0.421 0.000
R60.1 Generalised oedema
0.578 0.422 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.578 0.422 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.577 0.423 0.000
S50-S59 Injuries to the elbow and forearm
0.577 0.423 0.000
C67.8 Overlapping lesion of bladder
0.577 0.423 0.000
C67.7 Urachus
0.577 0.423 0.000
C67.6 Ureteric orifice
0.577 0.423 0.000
C67.5 Bladder neck
0.577 0.423 0.000
C67.4 Posterior wall of bladder
0.577 0.423 0.000
C67.3 Anterior wall of bladder
0.577 0.423 0.000
C67.1 Dome of bladder
0.577 0.423 0.000
C67.0 Trigone of bladder
0.577 0.423 0.000
C32 Malignant neoplasm of larynx
0.577 0.423 0.000
R25 Abnormal involuntary movements
0.576 0.424 0.000
M54.57 Low back pain (Lumbosacral region)
0.575 0.425 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.574 0.426 0.000
H02.6 Xanthelasma of eyelid
0.574 0.426 0.000
S99 Other and unspecified injuries of ankle and foot
0.573 0.427 0.000
S98 Traumatic amputation of ankle and foot
0.573 0.427 0.000
S97 Crushing injury of ankle and foot
0.573 0.427 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.573 0.427 0.000
S95 Injury of blood vessels at ankle and foot level
0.573 0.427 0.000
S94 Injury of nerves at ankle and foot level
0.573 0.427 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.573 0.427 0.000
S91 Open wound of ankle and foot
0.573 0.427 0.000
S79 Other and unspecified injuries of hip and thigh
0.573 0.427 0.000
H00 Hordeolum and chalazion
0.573 0.427 0.000
K76.6 Portal hypertension
0.573 0.427 0.000
H05.2 Exophthalmic conditions
0.572 0.428 0.000
M81 Osteoporosis without pathological fracture
0.572 0.428 0.000
R29.4 Clicking hip
0.571 0.429 0.000
R29.3 Abnormal posture
0.571 0.429 0.000
R29.2 Abnormal reflex
0.571 0.429 0.000
R29.1 Meningismus
0.571 0.429 0.000
R29.0 Tetany
0.571 0.429 0.000
S32.40 Fracture of acetabulum (closed)
0.571 0.429 0.000
K31 Other diseases of stomach and duodenum
0.571 0.429 0.000
G20-G26 Extrapyramidal and movement disorders
0.569 0.430 0.000
K25 Gastric ulcer
0.569 0.431 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.569 0.431 0.000
C16.0 Cardia
0.569 0.431 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.568 0.431 0.000
G90 Disorders of autonomic nervous system
0.568 0.431 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.568 0.431 0.000
G92 Toxic encephalopathy
0.568 0.431 0.000
S01.7 Multiple open wounds of head
0.567 0.433 0.000
S01.4 Open wound of cheek and temporomandibular area
0.567 0.433 0.000
S01.3 Open wound of ear
0.567 0.433 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.565 0.434 0.000
R26.3 Immobility
0.565 0.435 0.000
L27 Dermatitis due to substances taken internally
0.565 0.435 0.000
C88 Malignant immunoproliferative diseases
0.564 0.436 0.000
S80 Superficial injury of lower leg
0.563 0.436 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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