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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs73211928
log Bayes Factor = 9.06643
Chromosome 12   position 118,039,876  (GRCh37) Explore rs73211928 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
C79 Secondary malignant neoplasm of other sites
0.998 0.002 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.996 0.004 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.992 0.008 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.992 0.008 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.987 0.013 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.987 0.013 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.986 0.014 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.985 0.015 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.984 0.016 0.000
Chapter VI Diseases of the nervous system
0.981 0.019 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.978 0.022 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.970 0.030 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.969 0.031 0.000
M05-M14 Inflammatory polyarthropathies
0.966 0.034 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.966 0.034 0.000
R47-R49 Symptoms and signs involving speech and voice
0.965 0.035 0.000
Chapter VIII Diseases of the ear and mastoid process
0.957 0.043 0.000
O36 Maternal care for other known or suspected foetal problems
0.954 0.046 0.000
M06 Other rheumatoid arthritis
0.952 0.048 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.946 0.054 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.945 0.055 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.944 0.056 0.000
C78.0 Secondary malignant neoplasm of lung
0.944 0.056 0.000
R47 Speech disturbances, not elsewhere classified
0.937 0.063 0.000
R47.8 Other and unspecified speech disturbances
0.929 0.071 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.922 0.078 0.000
M86-M90 Other osteopathies
0.921 0.079 0.000
R25 Abnormal involuntary movements
0.919 0.081 0.000
O60-O75 Complications of labour and delivery
0.915 0.085 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.915 0.085 0.000
M06.9 Rheumatoid arthritis, unspecified
0.913 0.087 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.912 0.088 0.000
C34 Malignant neoplasm of bronchus and lung
0.906 0.094 0.000
D00-D09 In situ neoplasms
0.906 0.094 0.000
O36.8 Maternal care for other specified foetal problems
0.900 0.100 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.889 0.111 0.000
H90-H95 Other disorders of ear
0.888 0.112 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.886 0.114 0.000
C78.2 Secondary malignant neoplasm of pleura
0.883 0.117 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.879 0.121 0.000
M05 Seropositive rheumatoid arthritis
0.875 0.125 0.000
C34.9 Bronchus or lung, unspecified
0.874 0.126 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.871 0.129 0.000
R26 Abnormalities of gait and mobility
0.869 0.131 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.865 0.135 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.856 0.144 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.849 0.151 0.000
C85.1 B-cell lymphoma, unspecified
0.849 0.151 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.848 0.152 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.848 0.152 0.000
G40-G47 Episodic and paroxysmal disorders
0.846 0.154 0.000
M80-M85 Disorders of bone density and structure
0.844 0.156 0.000
R25.8 Other and unspecified abnormal involuntary movements
0.843 0.157 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.840 0.160 0.000
M89 Other disorders of bone
0.839 0.161 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.839 0.161 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.838 0.162 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.832 0.168 0.000
G83 Other paralytic syndromes
0.830 0.170 0.000
Chapter V Mental and behavioural disorders
0.829 0.171 0.000
C83.3 Large cell (diffuse)
0.827 0.173 0.000
C15-C26 Malignant neoplasms of digestive organs
0.826 0.174 0.000
O42 Premature rupture of membranes
0.818 0.182 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.816 0.184 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.816 0.184 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.812 0.188 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.811 0.189 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.810 0.190 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.810 0.190 0.000
M06.0 Seronegative rheumatoid arthritis
0.808 0.192 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.808 0.192 0.000
O47 False labour
0.808 0.192 0.000
G43 Migraine
0.806 0.194 0.000
H92 Otalgia and effusion of ear
0.805 0.195 0.000
D03 Melanoma in situ
0.804 0.196 0.000
R50-R69 General symptoms and signs
0.802 0.198 0.000
O85-O92 Complications predominantly related to the puerperium
0.801 0.199 0.000
O36.9 Maternal care for foetal problem, unspecified
0.798 0.202 0.000
M60-M63 Disorders of muscles
0.796 0.204 0.000
C16 Malignant neoplasm of stomach
0.792 0.208 0.000
M50-M54 Other dorsopathies
0.792 0.208 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.790 0.210 0.000
R29.6 Tendency to fall, not elsewhere classified
0.788 0.212 0.000
G82 Paraplegia and tetraplegia
0.787 0.213 0.000
C79.2 Secondary malignant neoplasm of skin
0.787 0.213 0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
0.786 0.213 0.000
O40 Polyhydramnios
0.786 0.214 0.000
G81 Hemiplegia
0.784 0.216 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.782 0.218 0.000
R69 Unknown and unspecified causes of morbidity
0.781 0.219 0.000
G43.9 Migraine, unspecified
0.780 0.220 0.000
M89.9 Disorder of bone, unspecified
0.779 0.221 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.779 0.221 0.000
M06.4 Inflammatory polyarthropathy
0.777 0.223 0.000
G80 Infantile cerebral palsy
0.777 0.223 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.772 0.228 0.000
R25.1 Tremor, unspecified
0.772 0.228 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.768 0.232 0.000
R44.0 Auditory hallucinations
0.767 0.233 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.766 0.234 0.000
D60-D64 Aplastic and other anaemias
0.765 0.235 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.764 0.236 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.763 0.237 0.000
M90 Osteopathies in diseases classified elsewhere
0.762 0.238 0.000
H80-H83 Diseases of inner ear
0.762 0.238 0.000
R44.1 Visual hallucinations
0.760 0.239 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.759 0.241 0.000
M91-M94 Chondropathies
0.757 0.243 0.000
G90-G99 Other disorders of the nervous system
0.757 0.243 0.000
Chapter X Diseases of the respiratory system
0.754 0.246 0.000
J30-J39 Other diseases of upper respiratory tract
0.753 0.247 0.000
H93 Other disorders of ear, not elsewhere classified
0.749 0.251 0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
0.749 0.251 0.000
M06.3 Rheumatoid nodule
0.749 0.251 0.000
G83.4 Cauda equina syndrome
0.747 0.253 0.000
H92.1 Otorrhoea
0.747 0.253 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.746 0.254 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.746 0.254 0.000
H65-H75 Diseases of middle ear and mastoid
0.746 0.254 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.746 0.254 0.000
O63 Long labour
0.746 0.254 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.745 0.254 0.000
C92 Myeloid leukaemia
0.743 0.256 0.000
G20-G26 Extrapyramidal and movement disorders
0.743 0.257 0.000
H60-H62 Diseases of external ear
0.742 0.258 0.000
C16.0 Cardia
0.739 0.261 0.000
O71 Other obstetric trauma
0.739 0.261 0.000
O42.9 Premature rupture of membranes, unspecified
0.738 0.262 0.000
O00-O08 Pregnancy with abortive outcome
0.737 0.263 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.737 0.263 0.000
O32.4 Maternal care for high head at term
0.737 0.263 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.736 0.264 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.734 0.266 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.734 0.266 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.731 0.269 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.731 0.269 0.000
C91 Lymphoid leukaemia
0.731 0.269 0.000
M80 Osteoporosis with pathological fracture
0.730 0.270 0.000
O66 Other obstructed labour
0.728 0.272 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.728 0.272 0.000
J33 Nasal polyp
0.728 0.272 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.727 0.273 0.000
G70-G73 Diseases of myoneural junction and muscle
0.726 0.274 0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)
0.725 0.275 0.000
R26.3 Immobility
0.724 0.276 0.000
G30-G32 Other degenerative diseases of the nervous system
0.723 0.277 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.721 0.279 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.721 0.279 0.000
O16 Unspecified maternal hypertension
0.720 0.280 0.000
O80-O84 Delivery
0.720 0.280 0.000
C34.1 Upper lobe, bronchus or lung
0.720 0.280 0.000
R49 Voice disturbances
0.719 0.281 0.000
M14 Arthropathies in other diseases classified elsewhere
0.718 0.282 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
C81 Hodgkin's disease
0.717 0.283 0.000
C88 Malignant immunoproliferative diseases
0.716 0.284 0.000
C79.6 Secondary malignant neoplasm of ovary
0.715 0.284 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.715 0.284 0.000
H90 Conductive and sensorineural hearing loss
0.715 0.285 0.000
M20-M25 Other joint disorders
0.715 0.285 0.000
O45 Premature separation of placenta [abruptio placentae]
0.714 0.286 0.000
O43 Placental disorders
0.714 0.286 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.714 0.286 0.000
O33 Maternal care for known or suspected disproportion
0.714 0.286 0.000
O31 Complications specific to multiple gestation
0.714 0.286 0.000
D63.0 Anaemia in neoplastic disease
0.714 0.286 0.000
D04 Carcinoma in situ of skin
0.713 0.287 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.712 0.288 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.711 0.288 0.000
C95 Leukaemia of unspecified cell type
0.711 0.288 0.000
C94 Other leukaemias of specified cell type
0.711 0.288 0.000
C93 Monocytic leukaemia
0.711 0.288 0.000
C86 Other specified types of T/NK-cell lymphoma
0.711 0.288 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.711 0.288 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.711 0.288 0.000
O97 Death from sequelae of direct obstetric causes
0.711 0.288 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.711 0.288 0.000
O95 Obstetric death of unspecified cause
0.711 0.288 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.711 0.288 0.000
R45 Symptoms and signs involving emotional state
0.711 0.289 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.708 0.292 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.708 0.292 0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium
0.707 0.292 0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
0.707 0.292 0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
0.707 0.292 0.000
O36.5 Maternal care for poor foetal growth
0.707 0.292 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.707 0.293 0.000
R25.3 Fasciculation
0.707 0.293 0.000
D70 Agranulocytosis
0.707 0.293 0.000
R27 Other lack of coordination
0.704 0.296 0.000
O44 Placenta praevia
0.704 0.296 0.000
R47.1 Dysarthria and anarthria
0.703 0.297 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.703 0.297 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.702 0.298 0.000
M88 Paget's disease of bone [osteitis deformans]
0.701 0.299 0.000
O30 Multiple gestation
0.700 0.300 0.000
M07 Psoriatic and enteropathic arthropathies
0.700 0.300 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.700 0.300 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.699 0.301 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.698 0.302 0.000
J33.9 Nasal polyp, unspecified
0.696 0.304 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.695 0.305 0.000
G90 Disorders of autonomic nervous system
0.695 0.305 0.000
M12 Other specific arthropathies
0.693 0.307 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.693 0.307 0.000
M08 Juvenile arthritis
0.693 0.307 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.692 0.307 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.692 0.307 0.000
C85.0 Lymphosarcoma
0.692 0.307 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.692 0.308 0.000
O41 Other disorders of amniotic fluid and membranes
0.692 0.308 0.000
C32 Malignant neoplasm of larynx
0.691 0.309 0.000
M00-M03 Infectious arthropathies
0.690 0.309 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.690 0.310 0.000
C16.9 Stomach, unspecified
0.689 0.311 0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
0.689 0.311 0.000
O72 Postpartum haemorrhage
0.688 0.312 0.000
M87 Osteonecrosis
0.688 0.312 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.686 0.314 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.686 0.314 0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy
0.684 0.316 0.000
O36.4 Maternal care for intra-uterine death
0.684 0.316 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.684 0.316 0.000
O36.2 Maternal care for hydrops foetalis
0.684 0.316 0.000
O36.1 Maternal care for other isoimmunisation
0.684 0.316 0.000
C51-C58 Malignant neoplasms of female genital organs
0.683 0.317 0.000
M06.8 Other specified rheumatoid arthritis
0.683 0.317 0.000
M06.2 Rheumatoid bursitis
0.683 0.317 0.000
M06.1 Adult-onset Still's disease
0.683 0.317 0.000
O32.1 Maternal care for breech presentation
0.682 0.318 0.000
D46 Myelodysplastic syndromes
0.681 0.319 0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
0.680 0.320 0.000
M40-M43 Deforming dorsopathies
0.679 0.321 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.679 0.321 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.679 0.321 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.679 0.321 0.000
C31 Malignant neoplasm of accessory sinuses
0.679 0.321 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.679 0.321 0.000
C37 Malignant neoplasm of thymus
0.679 0.321 0.000
C33 Malignant neoplasm of trachea
0.679 0.321 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.678 0.322 0.000
R46 Symptoms and signs involving appearance and behaviour
0.678 0.322 0.000
G82.2 Paraplegia, unspecified
0.678 0.322 0.000
F43 Reaction to severe stress, and adjustment disorders
0.678 0.322 0.000
O48 Prolonged pregnancy
0.677 0.323 0.000
J30 Vasomotor and allergic rhinitis
0.676 0.324 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.676 0.324 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.675 0.325 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.675 0.325 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.674 0.326 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.674 0.326 0.000
R68 Other general symptoms and signs
0.673 0.327 0.000
O69.8 Labour and delivery complicated by other cord complications
0.673 0.327 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.672 0.328 0.000
D07.5 Prostate
0.672 0.328 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.671 0.329 0.000
O69.2 Labour and delivery complicated by other cord entanglement
0.671 0.329 0.000
D09 Carcinoma in situ of other and unspecified sites
0.671 0.329 0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity
0.671 0.329 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.670 0.330 0.000
G81.9 Hemiplegia, unspecified
0.668 0.332 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.665 0.335 0.000
C34.3 Lower lobe, bronchus or lung
0.665 0.335 0.000
M85 Other disorders of bone density and structure
0.665 0.335 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.664 0.336 0.000
D72 Other disorders of white blood cells
0.663 0.337 0.000
O61 Failed induction of labour
0.662 0.337 0.000
Chapter XX External causes of morbidity and mortality
0.662 0.338 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.662 0.338 0.000
R54 Senility
0.662 0.338 0.000
F80-F89 Disorders of psychological development
0.661 0.338 0.000
M62 Other disorders of muscle
0.661 0.339 0.000
M24 Other specific joint derangements
0.659 0.341 0.000
R25.0 Abnormal head movements
0.659 0.341 0.000
D03.2 Melanoma in situ of ear and external auricular canal
0.659 0.341 0.000
O47.0 False labour before 37 completed weeks of gestation
0.659 0.341 0.000
R20 Disturbances of skin sensation
0.659 0.341 0.000
O32.8 Maternal care for other malpresentation of foetus
0.658 0.342 0.000
G62 Other polyneuropathies
0.657 0.343 0.000
G80.9 Infantile cerebral palsy, unspecified
0.657 0.343 0.000
O74 Complications of anaesthesia during labour and delivery
0.656 0.344 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.656 0.344 0.000
O60 Preterm delivery
0.656 0.344 0.000
R43 Disturbances of smell and taste
0.656 0.344 0.000
C78.7 Secondary malignant neoplasm of liver
0.655 0.345 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.655 0.345 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.655 0.345 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.655 0.345 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.655 0.345 0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified
0.654 0.346 0.000
O34.8 Maternal care for other abnormalities of pelvic organs
0.654 0.346 0.000
O34.6 Maternal care for abnormality of vagina
0.654 0.346 0.000
O34.5 Maternal care for other abnormalities of gravid uterus
0.654 0.346 0.000
O34.4 Maternal care for other abnormalities of cervix
0.654 0.346 0.000
O34.3 Maternal care for cervical incompetence
0.654 0.346 0.000
O34.0 Maternal care for congenital malformation of uterus
0.654 0.346 0.000
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions
0.653 0.346 0.000
M53 Other dorsopathies, not elsewhere classified
0.652 0.347 0.000
M11 Other crystal arthropathies
0.652 0.348 0.000
O63.1 Prolonged second stage (of labour)
0.651 0.349 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.651 0.349 0.000
M65-M68 Disorders of synovium and tendon
0.650 0.350 0.000
C34.8 Overlapping lesion of bronchus and lung
0.650 0.350 0.000
C34.2 Middle lobe, bronchus or lung
0.650 0.350 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.650 0.350 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.650 0.350 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.650 0.350 0.000
H81 Disorders of vestibular function
0.650 0.350 0.000
M90.7 Fracture of bone in neoplastic disease
0.648 0.352 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.647 0.353 0.000
M84 Disorders of continuity of bone
0.646 0.354 0.000
C71 Malignant neoplasm of brain
0.645 0.355 0.000
R26.0 Ataxic gait
0.645 0.355 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.644 0.356 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.644 0.356 0.000
C50-C50 Malignant neoplasm of breast
0.644 0.356 0.000
C80 Malignant neoplasm without specification of site
0.644 0.356 0.000
J39 Other diseases of upper respiratory tract
0.644 0.356 0.000
O03 Spontaneous abortion
0.643 0.357 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.642 0.358 0.000
S80-S89 Injuries to the knee and lower leg
0.639 0.361 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.639 0.361 0.000
D03.3 Melanoma in situ of other and unspecified parts of face
0.638 0.362 0.000
C23 Malignant neoplasm of gallbladder
0.638 0.362 0.000
H74 Other disorders of middle ear and mastoid
0.638 0.362 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.637 0.362 0.000
C83.7 Burkitt's tumour
0.637 0.362 0.000
C83.6 Undifferentiated (diffuse)
0.637 0.362 0.000
C83.5 Lymphoblastic (diffuse)
0.637 0.362 0.000
C83.4 Immunoblastic (diffuse)
0.637 0.362 0.000
C83.2 Mixed small and large cell (diffuse)
0.637 0.362 0.000
C83.1 Small cleaved cell (diffuse)
0.637 0.362 0.000
R40 Somnolence, stupor and coma
0.637 0.362 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.637 0.363 0.000
C15 Malignant neoplasm of oesophagus
0.637 0.363 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.637 0.363 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.636 0.363 0.000
D03.7 Melanoma in situ of lower limb, including hip
0.636 0.364 0.000
D55-D59 Haemolytic anaemias
0.635 0.365 0.000
O34.1 Maternal care for tumour of corpus uteri
0.635 0.365 0.000
O75.8 Other specified complications of labour and delivery
0.635 0.365 0.000
O70 Perineal laceration during delivery
0.634 0.366 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.633 0.367 0.000
R50 Fever of unknown origin
0.633 0.367 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.633 0.367 0.000
O90 Complications of the puerperium, not elsewhere classified
0.632 0.368 0.000
R29.4 Clicking hip
0.630 0.369 0.000
R29.3 Abnormal posture
0.630 0.369 0.000
R29.2 Abnormal reflex
0.630 0.369 0.000
R29.1 Meningismus
0.630 0.369 0.000
R29.0 Tetany
0.630 0.369 0.000
R21 Rash and other nonspecific skin eruption
0.629 0.371 0.000
R45.1 Restlessness and agitation
0.629 0.371 0.000
D03.6 Melanoma in situ of upper limb, including shoulder
0.629 0.371 0.000
M05.8 Other seropositive rheumatoid arthritis
0.627 0.372 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.627 0.372 0.000
M05.2 Rheumatoid vasculitis
0.627 0.372 0.000
M05.1 Rheumatoid lung disease
0.627 0.372 0.000
M05.0 Felty's syndrome
0.627 0.372 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.627 0.373 0.000
G44 Other headache syndromes
0.627 0.373 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.626 0.374 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.625 0.375 0.000
R44.3 Hallucinations, unspecified
0.625 0.375 0.000
O32.9 Maternal care for malpresentation of foetus, unspecified
0.624 0.376 0.000
O32.6 Maternal care for compound presentation
0.624 0.376 0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more
0.624 0.376 0.000
O32.3 Maternal care for face, brow and chin presentation
0.624 0.376 0.000
O32.2 Maternal care for transverse and oblique lie
0.624 0.376 0.000
R26.1 Paralytic gait
0.623 0.377 0.000
O32.0 Maternal care for unstable lie
0.622 0.377 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.622 0.378 0.000
M54 Dorsalgia
0.622 0.378 0.000
J30.1 Allergic rhinitis due to pollen
0.622 0.378 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.620 0.380 0.000
R44.2 Other hallucinations
0.620 0.380 0.000
C45 Mesothelioma
0.620 0.380 0.000
H66 Suppurative and unspecified otitis media
0.619 0.381 0.000
Chapter XXII Codes for special purposes
0.619 0.381 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.618 0.382 0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified
0.617 0.383 0.000
O62 Abnormalities of forces of labour
0.616 0.384 0.000
C64-C68 Malignant neoplasms of urinary tract
0.616 0.384 0.000
F45 Somatoform disorders
0.616 0.384 0.000
O64.1 Obstructed labour due to breech presentation
0.615 0.385 0.000
M86 Osteomyelitis
0.615 0.385 0.000
O72.1 Other immediate postpartum haemorrhage
0.615 0.385 0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
0.614 0.386 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.613 0.386 0.000
R59 Enlarged lymph nodes
0.613 0.387 0.000
C17 Malignant neoplasm of small intestine
0.613 0.387 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.613 0.387 0.000
O71.8 Other specified obstetric trauma
0.612 0.388 0.000
O69.1 Labour and delivery complicated by cord around neck, with compression
0.612 0.388 0.000
R20.2 Paraesthesia of skin
0.612 0.388 0.000
S32 Fracture of lumbar spine and pelvis
0.612 0.388 0.000
O86 Other puerperal infections
0.609 0.391 0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.609 0.391 0.000
C46 Kaposi's sarcoma
0.609 0.391 0.000
M94 Other disorders of cartilage
0.609 0.391 0.000
H93.1 Tinnitus
0.608 0.392 0.000
O15 Eclampsia
0.608 0.392 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.608 0.392 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.608 0.392 0.000
M89.8 Other specified disorders of bone
0.608 0.392 0.000
G62.9 Polyneuropathy, unspecified
0.608 0.392 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.606 0.393 0.000
J95-J99 Other diseases of the respiratory system
0.605 0.395 0.000
M83 Adult osteomalacia
0.605 0.395 0.000
M82 Osteoporosis in diseases classified elsewhere
0.605 0.395 0.000
M89.94 Disorder of bone, unspecified (Hand)
0.605 0.395 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.604 0.396 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.604 0.396 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.604 0.396 0.000
M50 Cervical disk disorders
0.604 0.396 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.604 0.396 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.603 0.397 0.000
M06.34 Rheumatoid nodule (Hand)
0.603 0.397 0.000
D75 Other diseases of blood and blood-forming organs
0.602 0.398 0.000
F01 Vascular dementia
0.602 0.398 0.000
M89.6 Osteopathy after poliomyelitis
0.602 0.398 0.000
M89.5 Osteolysis
0.602 0.398 0.000
M89.4 Other hypertrophic osteo-arthropathy
0.602 0.398 0.000
M89.3 Hypertrophy of bone
0.602 0.398 0.000
M89.2 Other disorders of bone development and growth
0.602 0.398 0.000
M89.1 Epiphyseal arrest
0.602 0.398 0.000
M89.0 Algoneurodystrophy
0.602 0.398 0.000
R93.6 Abnormal findings on diagnostic imaging of limbs
0.602 0.398 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.602 0.398 0.000
R52 Pain, not elsewhere classified
0.602 0.398 0.000
C90.2 Plasmacytoma, extramedullary
0.602 0.398 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.601 0.399 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.601 0.399 0.000
G03 Meningitis due to other and unspecified causes
0.601 0.399 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.601 0.399 0.000
G00 Bacterial meningitis, not elsewhere classified
0.601 0.399 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.601 0.399 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.601 0.399 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.601 0.399 0.000
H93.9 Disorder of ear, unspecified
0.600 0.400 0.000
O82 Single delivery by Caesarean section
0.599 0.401 0.000
J35 Chronic diseases of tonsils and adenoids
0.598 0.402 0.000
R84 Abnormal findings in specimens from respiratory organs and thorax
0.597 0.402 0.000
C92.1 Chronic myeloid leukaemia
0.597 0.403 0.000
H60 Otitis externa
0.595 0.405 0.000
G83.9 Paralytic syndrome, unspecified
0.595 0.405 0.000
G83.8 Other specified paralytic syndromes
0.595 0.405 0.000
G83.5 Locked-in syndrome
0.595 0.405 0.000
G83.3 Monoplegia, unspecified
0.595 0.405 0.000
G83.2 Monoplegia of upper limb
0.595 0.405 0.000
G83.1 Monoplegia of lower limb
0.595 0.405 0.000
G83.0 Diplegia of upper limbs
0.595 0.405 0.000
O75.0 Maternal distress during labour and delivery
0.595 0.405 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.595 0.405 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.594 0.405 0.000
F70-F79 Mental retardation
0.594 0.405 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.593 0.407 0.000
F43.1 Posttraumatic stress disorder
0.593 0.407 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.593 0.407 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.592 0.408 0.000
G60 Hereditary and idiopathic neuropathy
0.592 0.408 0.000
G93 Other disorders of brain
0.592 0.408 0.000
F48 Other neurotic disorders
0.590 0.409 0.000
G41 Status epilepticus
0.590 0.410 0.000
J33.8 Other polyp of sinus
0.589 0.411 0.000
O36.6 Maternal care for excessive foetal growth
0.589 0.411 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.588 0.412 0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified
0.588 0.412 0.000
G20 Parkinson's disease
0.587 0.413 0.000
G90.2 Horner's syndrome
0.587 0.413 0.000
D05 Carcinoma in situ of breast
0.587 0.413 0.000
O42.2 Premature rupture of membranes, labour delayed by therapy
0.586 0.414 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.585 0.415 0.000
C91.4 Hairy-cell leukaemia
0.585 0.415 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.585 0.415 0.000
D45 Polycythaemia vera
0.584 0.416 0.000
C21 Malignant neoplasm of anus and anal canal
0.584 0.416 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.584 0.416 0.000
O03.4 Incomplete, without complication
0.584 0.416 0.000
R86 Abnormal findings in specimens from male genital organs
0.582 0.418 0.000
O69.9 Labour and delivery complicated by cord complication, unspecified
0.582 0.418 0.000
O69.5 Labour and delivery complicated by vascular lesion of cord
0.582 0.418 0.000
O69.4 Labour and delivery complicated by vasa praevia
0.582 0.418 0.000
O69.3 Labour and delivery complicated by short cord
0.582 0.418 0.000
O69.0 Labour and delivery complicated by prolapse of cord
0.582 0.418 0.000
R89 Abnormal findings in specimens from other organs, systems and tissues
0.582 0.418 0.000
R83 Abnormal findings in cerebrospinal fluid
0.582 0.418 0.000
R23 Other skin changes
0.581 0.418 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.581 0.419 0.000
F41 Other anxiety disorders
0.581 0.419 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.581 0.419 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.581 0.419 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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