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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74013184
log Bayes Factor = 7.38165
Chromosome 16   position 24,363,769  (GRCh37) Explore rs74013184 on Ensembl!
Variant rs74013184 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
Chapter II Neoplasms
0.992 0.008 0.000
I30-I52 Other forms of heart disease
0.988 0.012 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.983 0.017 0.000
Chapter XXI Factors influencing health status and contact with health services
0.972 0.028 0.000
Chapter XIV Diseases of the genitourinary system
0.967 0.033 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.965 0.035 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.965 0.035 0.000
Chapter XI Diseases of the digestive system
0.956 0.044 0.000
N17-N19 Renal failure
0.947 0.053 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.944 0.056 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.935 0.065 0.000
I35 Nonrheumatic aortic valve disorders
0.921 0.079 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.919 0.081 0.000
D50-D53 Nutritional anaemias
0.918 0.082 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.918 0.082 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.917 0.083 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.916 0.084 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.905 0.095 0.000
I10-I15 Hypertensive diseases
0.900 0.100 0.000
I20-I25 Ischaemic heart diseases
0.899 0.101 0.000
Chapter X Diseases of the respiratory system
0.899 0.101 0.000
I60-I69 Cerebrovascular diseases
0.896 0.104 0.000
K80 Cholelithiasis
0.893 0.107 0.000
I34 Nonrheumatic mitral valve disorders
0.887 0.113 0.000
Chapter VIII Diseases of the ear and mastoid process
0.883 0.117 0.000
N18 Chronic renal failure
0.879 0.121 0.000
D50 Iron deficiency anaemia
0.879 0.121 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.876 0.124 0.000
Chapter XX External causes of morbidity and mortality
0.874 0.126 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.874 0.126 0.000
I50 Heart failure
0.872 0.128 0.000
C15-C26 Malignant neoplasms of digestive organs
0.870 0.130 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.868 0.132 0.000
Z45 Adjustment and management of implanted device
0.866 0.134 0.000
K13 Other diseases of lip and oral mucosa
0.864 0.136 0.000
I51 Complications and ill-defined descriptions of heart disease
0.854 0.146 0.000
C51-C58 Malignant neoplasms of female genital organs
0.841 0.159 0.000
I10 Essential (primary) hypertension
0.840 0.160 0.000
Z51 Other medical care
0.838 0.162 0.000
D50.9 Iron deficiency anaemia, unspecified
0.837 0.163 0.000
I05-I09 Chronic rheumatic heart diseases
0.835 0.165 0.000
N17 Acute renal failure
0.835 0.165 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.830 0.170 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.826 0.174 0.000
S60-S69 Injuries to the wrist and hand
0.825 0.175 0.000
K13.7 Other and unspecified lesions of oral mucosa
0.824 0.176 0.000
C78.7 Secondary malignant neoplasm of liver
0.824 0.176 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.819 0.181 0.000
Chapter I Certain infectious and parasitic diseases
0.818 0.182 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.818 0.182 0.000
Z45.2 Adjustment and management of vascular access device
0.816 0.184 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.814 0.186 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.812 0.188 0.000
N30-N39 Other diseases of urinary system
0.810 0.190 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.810 0.190 0.000
I44 Atrioventricular and left bundle-branch block
0.807 0.193 0.000
N19 Unspecified renal failure
0.807 0.193 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.806 0.194 0.000
K08 Other disorders of teeth and supporting structures
0.805 0.195 0.000
I34.0 Mitral (valve) insufficiency
0.805 0.195 0.000
C78.0 Secondary malignant neoplasm of lung
0.801 0.199 0.000
K82 Other diseases of gallbladder
0.796 0.204 0.000
I50.0 Congestive heart failure
0.795 0.205 0.000
H65-H75 Diseases of middle ear and mastoid
0.794 0.206 0.000
I25 Chronic ischaemic heart disease
0.792 0.208 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.790 0.210 0.000
I35.0 Aortic (valve) stenosis
0.786 0.214 0.000
Z47 Other orthopaedic follow-up care
0.784 0.216 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.782 0.218 0.000
Z37 Outcome of delivery
0.782 0.218 0.000
Z51.1 Chemotherapy session for neoplasm
0.781 0.219 0.000
I63 Cerebral infarction
0.776 0.224 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.775 0.225 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.773 0.227 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.769 0.230 0.000
Chapter XXII Codes for special purposes
0.769 0.231 0.000
N60-N64 Disorders of breast
0.769 0.231 0.000
N18.3 Chronic kidney disease, stage 3
0.767 0.233 0.000
J95-J99 Other diseases of the respiratory system
0.766 0.234 0.000
J40-J47 Chronic lower respiratory diseases
0.764 0.235 0.000
C18 Malignant neoplasm of colon
0.759 0.241 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.757 0.243 0.000
J90-J94 Other diseases of pleura
0.755 0.245 0.000
N17.9 Acute renal failure, unspecified
0.755 0.245 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.753 0.247 0.000
I69 Sequelae of cerebrovascular disease
0.752 0.248 0.000
S62 Fracture at wrist and hand level
0.749 0.251 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.747 0.253 0.000
K81 Cholecystitis
0.746 0.254 0.000
K80.4 Calculus of bile duct with cholecystitis
0.745 0.255 0.000
N73 Other female pelvic inflammatory diseases
0.745 0.255 0.000
E70-E90 Metabolic disorders
0.742 0.258 0.000
N10-N16 Renal tubulo-interstitial diseases
0.737 0.263 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.736 0.264 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.736 0.264 0.000
Z50 Care involving use of rehabilitation procedures
0.734 0.265 0.000
R47-R49 Symptoms and signs involving speech and voice
0.734 0.266 0.000
C77.4 Inguinal and lower limb lymph nodes
0.733 0.267 0.000
K08.3 Retained dental root
0.733 0.267 0.000
S80-S89 Injuries to the knee and lower leg
0.733 0.267 0.000
C56 Malignant neoplasm of ovary
0.731 0.269 0.000
R50-R69 General symptoms and signs
0.731 0.269 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.730 0.270 0.000
I42 Cardiomyopathy
0.730 0.270 0.000
N00-N08 Glomerular diseases
0.729 0.270 0.000
R10 Abdominal and pelvic pain
0.729 0.271 0.000
O60-O75 Complications of labour and delivery
0.729 0.271 0.000
Chapter V Mental and behavioural disorders
0.729 0.271 0.000
K11 Diseases of salivary glands
0.728 0.272 0.000
D70 Agranulocytosis
0.726 0.274 0.000
I51.8 Other ill-defined heart diseases
0.726 0.274 0.000
C78.2 Secondary malignant neoplasm of pleura
0.725 0.275 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.725 0.275 0.000
C77.9 Lymph node, unspecified
0.722 0.278 0.000
Z37.0 Single live birth
0.720 0.280 0.000
C79 Secondary malignant neoplasm of other sites
0.719 0.280 0.000
I08 Multiple valve diseases
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.711 0.289 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.711 0.289 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.711 0.289 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.711 0.289 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.711 0.289 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.711 0.289 0.000
I22 Subsequent myocardial infarction
0.711 0.289 0.000
K65-K67 Diseases of peritoneum
0.710 0.289 0.000
R94 Abnormal results of function studies
0.710 0.290 0.000
D00-D09 In situ neoplasms
0.709 0.291 0.000
I52 Other heart disorders in diseases classified elsewhere
0.708 0.292 0.000
I48 Atrial fibrillation and flutter
0.708 0.292 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.708 0.292 0.000
I41 Myocarditis in diseases classified elsewhere
0.708 0.292 0.000
I40 Acute myocarditis
0.708 0.292 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.708 0.292 0.000
I37 Pulmonary valve disorders
0.708 0.292 0.000
I36 Nonrheumatic tricuspid valve disorders
0.708 0.292 0.000
I33 Acute and subacute endocarditis
0.708 0.292 0.000
I32 Pericarditis in diseases classified elsewhere
0.708 0.292 0.000
I30 Acute pericarditis
0.708 0.292 0.000
I38 Endocarditis, valve unspecified
0.708 0.292 0.000
N18.4 Chronic kidney disease, stage 4
0.707 0.293 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.707 0.293 0.000
K85 Acute pancreatitis
0.705 0.295 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.705 0.295 0.000
C80 Malignant neoplasm without specification of site
0.705 0.295 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.705 0.295 0.000
M20-M25 Other joint disorders
0.705 0.295 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.704 0.296 0.000
I21 Acute myocardial infarction
0.703 0.297 0.000
M80-M85 Disorders of bone density and structure
0.703 0.297 0.000
K12 Stomatitis and related lesions
0.702 0.298 0.000
N75 Diseases of Bartholin's gland
0.702 0.298 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.701 0.299 0.000
Z53.9 Procedure not carried out, unspecified reason
0.701 0.299 0.000
N39 Other disorders of urinary system
0.701 0.299 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.699 0.301 0.000
D50.8 Other iron deficiency anaemias
0.698 0.302 0.000
N18.9 Chronic renal failure, unspecified
0.698 0.302 0.000
I35.1 Aortic (valve) insufficiency
0.697 0.303 0.000
D51 Vitamin B12 deficiency anaemia
0.697 0.303 0.000
K90-K93 Other diseases of the digestive system
0.696 0.304 0.000
K82.8 Other specified diseases of gallbladder
0.695 0.305 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.695 0.305 0.000
C64-C68 Malignant neoplasms of urinary tract
0.695 0.305 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.694 0.306 0.000
D80-D89 Certain disorders involving the immune mechanism
0.692 0.308 0.000
D55-D59 Haemolytic anaemias
0.692 0.308 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.692 0.308 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.692 0.308 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.692 0.308 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.692 0.308 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.692 0.308 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.692 0.308 0.000
W00-W19 Falls
0.691 0.309 0.000
D60-D64 Aplastic and other anaemias
0.690 0.310 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.690 0.310 0.000
N99-N99 Other disorders of the genitourinary system
0.690 0.310 0.000
T66-T78 Other and unspecified effects of external causes
0.689 0.311 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.689 0.311 0.000
N72 Inflammatory disease of cervix uteri
0.688 0.312 0.000
I31 Other diseases of pericardium
0.688 0.312 0.000
J00-J06 Acute upper respiratory infections
0.687 0.312 0.000
K14 Diseases of tongue
0.686 0.314 0.000
I50.9 Heart failure, unspecified
0.685 0.314 0.000
S50-S59 Injuries to the elbow and forearm
0.685 0.315 0.000
W20-W49 Exposure to inanimate mechanical forces
0.685 0.315 0.000
S62.6 Fracture of other finger
0.685 0.315 0.000
R10.1 Pain localised to upper abdomen
0.684 0.316 0.000
I51.7 Cardiomegaly
0.684 0.316 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.682 0.318 0.000
I46 Cardiac arrest
0.681 0.318 0.000
O80-O84 Delivery
0.681 0.319 0.000
H80-H83 Diseases of inner ear
0.681 0.319 0.000
K70-K77 Diseases of liver
0.679 0.321 0.000
K04 Diseases of pulp and periapical tissues
0.677 0.322 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.677 0.323 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.677 0.323 0.000
Z54 Convalescence
0.677 0.323 0.000
Z52 Donors of organs and tissues
0.677 0.323 0.000
Z49 Care involving dialysis
0.677 0.323 0.000
Z44 Fitting and adjustment of external prosthetic device
0.677 0.323 0.000
Z41 Procedures for purposes other than remedying health state
0.677 0.323 0.000
M05-M14 Inflammatory polyarthropathies
0.676 0.324 0.000
Z48 Other surgical follow-up care
0.674 0.325 0.000
Z72 Problems related to lifestyle
0.673 0.327 0.000
I44.2 Atrioventricular block, complete
0.673 0.327 0.000
I45 Other conduction disorders
0.672 0.327 0.000
I44.0 Atrioventricular block, first degree
0.672 0.328 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.671 0.329 0.000
K86 Other diseases of pancreas
0.671 0.329 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.670 0.330 0.000
N18.5 Chronic kidney disease, stage 5
0.669 0.330 0.000
C50-C50 Malignant neoplasm of breast
0.668 0.331 0.000
I34.1 Mitral (valve) prolapse
0.668 0.332 0.000
Z45.8 Adjustment and management of other implanted devices
0.668 0.332 0.000
I24 Other acute ischaemic heart diseases
0.665 0.335 0.000
C77.1 Intrathoracic lymph nodes
0.663 0.337 0.000
S70-S79 Injuries to the hip and thigh
0.663 0.337 0.000
A30-A49 Other bacterial diseases
0.662 0.338 0.000
I35.9 Aortic valve disorder, unspecified
0.660 0.340 0.000
I35.8 Other aortic valve disorders
0.660 0.340 0.000
K83 Other diseases of biliary tract
0.659 0.341 0.000
H65 Nonsuppurative otitis media
0.659 0.341 0.000
K10 Other diseases of jaws
0.659 0.341 0.000
K09 Cysts of oral region, not elsewhere classified
0.659 0.341 0.000
K07 Dentofacial anomalies [including malocclusion]
0.659 0.341 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.659 0.341 0.000
K05 Gingivitis and periodontal diseases
0.659 0.341 0.000
K03 Other diseases of hard tissues of teeth
0.659 0.341 0.000
K00 Disorders of tooth development and eruption
0.659 0.341 0.000
D53 Other nutritional anaemias
0.658 0.342 0.000
D52 Folate deficiency anaemia
0.658 0.342 0.000
J44 Other chronic obstructive pulmonary disease
0.658 0.342 0.000
R53 Malaise and fatigue
0.657 0.342 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.657 0.343 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.657 0.343 0.000
Z36 Antenatal screening
0.657 0.343 0.000
Z46 Fitting and adjustment of other devices
0.657 0.343 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.657 0.343 0.000
T79-T79 Certain early complications of trauma
0.657 0.343 0.000
T33-T35 Frostbite
0.657 0.343 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.657 0.343 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.657 0.343 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.657 0.343 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.657 0.343 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.657 0.343 0.000
T00-T07 Injuries involving multiple body regions
0.657 0.343 0.000
S90-S99 Injuries to the ankle and foot
0.657 0.343 0.000
S10-S19 Injuries to the neck
0.657 0.343 0.000
R17 Unspecified jaundice
0.654 0.346 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.654 0.346 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.653 0.346 0.000
N73.6 Female pelvic peritoneal adhesions
0.653 0.347 0.000
R07 Pain in throat and chest
0.653 0.347 0.000
Z33 Pregnant state, incidental
0.652 0.348 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.649 0.350 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.649 0.351 0.000
O85-O92 Complications predominantly related to the puerperium
0.648 0.351 0.000
K35-K38 Diseases of appendix
0.648 0.352 0.000
Z34 Supervision of normal pregnancy
0.648 0.352 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.648 0.352 0.000
C60-C63 Malignant neoplasms of male genital organs
0.646 0.354 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.646 0.354 0.000
N35 Urethral stricture
0.645 0.355 0.000
I15 Secondary hypertension
0.645 0.355 0.000
I13 Hypertensive heart and renal disease
0.645 0.355 0.000
I11 Hypertensive heart disease
0.645 0.355 0.000
Z40 Prophylactic surgery
0.645 0.355 0.000
I23 Certain current complications following acute myocardial infarction
0.645 0.355 0.000
N25-N29 Other disorders of kidney and ureter
0.645 0.355 0.000
B25-B34 Other viral diseases
0.644 0.356 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.644 0.356 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.644 0.356 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.644 0.356 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.644 0.356 0.000
R94.5 Abnormal results of liver function studies
0.643 0.357 0.000
Z51.3 Blood transfusion without reported diagnosis
0.643 0.357 0.000
J43 Emphysema
0.643 0.357 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.643 0.357 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.643 0.357 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.643 0.357 0.000
I62 Other nontraumatic intracranial haemorrhage
0.643 0.357 0.000
I61 Intracerebral haemorrhage
0.643 0.357 0.000
I60 Subarachnoid haemorrhage
0.643 0.357 0.000
H72 Perforation of tympanic membrane
0.642 0.358 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.642 0.358 0.000
K80.3 Calculus of bile duct with cholangitis
0.640 0.360 0.000
K80.8 Other cholelithiasis
0.640 0.360 0.000
S00-S09 Injuries to the head
0.640 0.360 0.000
S20-S29 Injuries to the thorax
0.639 0.360 0.000
H66 Suppurative and unspecified otitis media
0.639 0.361 0.000
S62.60 Fracture of other finger (closed)
0.639 0.361 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.637 0.363 0.000
K50-K52 Noninfective enteritis and colitis
0.637 0.363 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.636 0.364 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.636 0.364 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.636 0.364 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.636 0.364 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.635 0.365 0.000
C77.0 Lymph nodes of head, face and neck
0.633 0.366 0.000
H60-H62 Diseases of external ear
0.633 0.367 0.000
O00-O08 Pregnancy with abortive outcome
0.632 0.368 0.000
E10-E14 Diabetes mellitus
0.632 0.368 0.000
S40-S49 Injuries to the shoulder and upper arm
0.632 0.368 0.000
R18 Ascites
0.632 0.368 0.000
C34 Malignant neoplasm of bronchus and lung
0.632 0.368 0.000
J98 Other respiratory disorders
0.631 0.369 0.000
N18.8 Other chronic renal failure
0.631 0.369 0.000
N18.2 Chronic kidney disease, stage 2
0.631 0.369 0.000
N18.1 Chronic kidney disease, stage 1
0.631 0.369 0.000
N18.0 End-stage renal disease
0.631 0.369 0.000
D50.1 Sideropenic dysphagia
0.630 0.370 0.000
M25 Other joint disorders, not elsewhere classified
0.630 0.370 0.000
J60-J70 Lung diseases due to external agents
0.630 0.370 0.000
I63.9 Cerebral infarction, unspecified
0.629 0.371 0.000
C77.2 Intra-abdominal lymph nodes
0.629 0.371 0.000
C77.8 Lymph nodes of multiple regions
0.628 0.372 0.000
C77.5 Intrapelvic lymph nodes
0.628 0.372 0.000
J90 Pleural effusion, not elsewhere classified
0.628 0.372 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.626 0.373 0.000
Y35-Y36 Legal intervention and operations of war
0.626 0.373 0.000
Y10-Y34 Event of undetermined intent
0.626 0.373 0.000
Y00-Y09 Assault
0.626 0.373 0.000
X85-X99 Assault
0.626 0.373 0.000
X60-X84 Intentional self-harm
0.626 0.373 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.626 0.373 0.000
X50-X57 Overexertion, travel and privation
0.626 0.373 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.626 0.373 0.000
X30-X39 Exposure to forces of nature
0.626 0.373 0.000
X20-X29 Contact with venomous animals and plants
0.626 0.373 0.000
X10-X19 Contact with heat and hot substances
0.626 0.373 0.000
X00-X09 Exposure to smoke, fire and flames
0.626 0.373 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.626 0.373 0.000
W75-W84 Other accidental threats to breathing
0.626 0.373 0.000
W65-W74 Accidental drowning and submersion
0.626 0.373 0.000
W50-W64 Exposure to animate mechanical forces
0.626 0.373 0.000
V98-V99 Other and unspecified transport accidents
0.626 0.373 0.000
V95-V97 Air and space transport accidents
0.626 0.373 0.000
V90-V94 Water transport accidents
0.626 0.373 0.000
V80-V89 Other land transport accidents
0.626 0.373 0.000
V70-V79 Bus occupant injured in transport accident
0.626 0.373 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.626 0.373 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.626 0.373 0.000
V40-V49 Car occupant injured in transport accident
0.626 0.373 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.626 0.373 0.000
V20-V29 Motorcycle rider injured in transport accident
0.626 0.373 0.000
V10-V19 Pedal cyclist injured in transport accident
0.626 0.373 0.000
V01-V09 Pedestrian injured in transport accident
0.626 0.373 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.626 0.373 0.000
N76 Other inflammation of vagina and vulva
0.626 0.373 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.626 0.373 0.000
N71 Inflammatory disease of uterus, except cervix
0.626 0.373 0.000
N70 Salpingitis and oophoritis
0.626 0.373 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.626 0.373 0.000
I49 Other cardiac arrhythmias
0.626 0.374 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.624 0.376 0.000
C25 Malignant neoplasm of pancreas
0.624 0.376 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.624 0.376 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.624 0.376 0.000
C21 Malignant neoplasm of anus and anal canal
0.624 0.376 0.000
C17 Malignant neoplasm of small intestine
0.624 0.376 0.000
C16 Malignant neoplasm of stomach
0.624 0.376 0.000
C15 Malignant neoplasm of oesophagus
0.624 0.376 0.000
C23 Malignant neoplasm of gallbladder
0.624 0.376 0.000
S61 Open wound of wrist and hand
0.624 0.376 0.000
C77.3 Axillary and upper limb lymph nodes
0.623 0.377 0.000
Z39 Postpartum care and examination
0.622 0.377 0.000
Z38 Liveborn infants according to place of birth
0.622 0.377 0.000
Z35 Supervision of high-risk pregnancy
0.622 0.377 0.000
Z32 Pregnancy examination and test
0.622 0.377 0.000
Z31 Procreative management
0.622 0.377 0.000
Z45.9 Adjustment and management of unspecified implanted device
0.621 0.379 0.000
Z45.3 Adjustment and management of implanted hearing device
0.621 0.379 0.000
Z45.1 Adjustment and management of infusion pump
0.621 0.379 0.000
N39.3 Stress incontinence
0.620 0.380 0.000
N62 Hypertrophy of breast
0.619 0.381 0.000
K13.2 Leukoplakia and other disturbances of oral epithelium, including tongue
0.619 0.381 0.000
K13.6 Irritative hyperplasia of oral mucosa
0.619 0.381 0.000
K13.5 Oral submucous fibrosis
0.619 0.381 0.000
K13.4 Granuloma and granuloma-like lesions of oral mucosa
0.619 0.381 0.000
K13.3 Hairy leukoplakia
0.619 0.381 0.000
K13.1 Cheek and lip biting
0.619 0.381 0.000
K13.0 Diseases of lips
0.619 0.381 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.619 0.381 0.000
E20-E35 Disorders of other endocrine glands
0.619 0.381 0.000
R07.4 Chest pain, unspecified
0.619 0.381 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.617 0.383 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.616 0.384 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.615 0.384 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.613 0.387 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.613 0.387 0.000
I51.6 Cardiovascular disease, unspecified
0.612 0.388 0.000
I51.5 Myocardial degeneration
0.612 0.388 0.000
I51.4 Myocarditis, unspecified
0.612 0.388 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.612 0.388 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.612 0.388 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.612 0.388 0.000
I51.0 Cardiac septal defect, acquired
0.612 0.388 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.612 0.388 0.000
N64 Other disorders of breast
0.611 0.388 0.000
C18.7 Sigmoid colon
0.610 0.390 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.610 0.390 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.609 0.391 0.000
J42 Unspecified chronic bronchitis
0.609 0.391 0.000
R13 Dysphagia
0.608 0.392 0.000
C54 Malignant neoplasm of corpus uteri
0.608 0.392 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.608 0.392 0.000
Z75 Problems related to medical facilities and other health care
0.607 0.393 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.606 0.394 0.000
C18.9 Colon, unspecified
0.605 0.395 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.603 0.396 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.603 0.397 0.000
C53 Malignant neoplasm of cervix uteri
0.603 0.397 0.000
C51 Malignant neoplasm of vulva
0.603 0.397 0.000
C58 Malignant neoplasm of placenta
0.603 0.397 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.603 0.397 0.000
C52 Malignant neoplasm of vagina
0.603 0.397 0.000
J92 Pleural plaque
0.603 0.397 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.601 0.399 0.000
R01 Cardiac murmurs and other cardiac sounds
0.601 0.399 0.000
Z51.9 Medical care, unspecified
0.601 0.399 0.000
Z51.6 Desensitisation to allergens
0.601 0.399 0.000
K81.0 Acute cholecystitis
0.600 0.399 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.599 0.400 0.000
I09 Other rheumatic heart diseases
0.599 0.401 0.000
I07 Rheumatic tricuspid valve diseases
0.599 0.401 0.000
I06 Rheumatic aortic valve diseases
0.599 0.401 0.000
I05 Rheumatic mitral valve diseases
0.599 0.401 0.000
Z53.0 Procedure not carried out because of contraindication
0.599 0.401 0.000
N17.8 Other acute renal failure
0.598 0.401 0.000
N17.2 Acute renal failure with medullary necrosis
0.598 0.401 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.598 0.401 0.000
N17.0 Acute renal failure with tubular necrosis
0.598 0.401 0.000
I51.9 Heart disease, unspecified
0.598 0.402 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.597 0.402 0.000
I12 Hypertensive renal disease
0.597 0.403 0.000
M45-M49 Spondylopathies
0.597 0.403 0.000
R59 Enlarged lymph nodes
0.596 0.404 0.000
E40-E46 Malnutrition
0.595 0.405 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.595 0.405 0.000
Z43 Attention to artificial openings
0.594 0.405 0.000
Q60-Q64 Congenital malformations of the urinary system
0.594 0.406 0.000
I67 Other cerebrovascular diseases
0.593 0.407 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.593 0.407 0.000
C20 Malignant neoplasm of rectum
0.592 0.408 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.592 0.408 0.000
D75 Other diseases of blood and blood-forming organs
0.592 0.408 0.000
D74 Methaemoglobinaemia
0.592 0.408 0.000
D73 Diseases of spleen
0.592 0.408 0.000
D72 Other disorders of white blood cells
0.592 0.408 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.592 0.408 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.592 0.408 0.000
K11.2 Sialoadenitis
0.591 0.408 0.000
S69 Other and unspecified injuries of wrist and hand
0.591 0.409 0.000
S68 Traumatic amputation of wrist and hand
0.591 0.409 0.000
S67 Crushing injury of wrist and hand
0.591 0.409 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.591 0.409 0.000
S65 Injury of blood vessels at wrist and hand level
0.591 0.409 0.000
S64 Injury of nerves at wrist and hand level
0.591 0.409 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.591 0.409 0.000
S60 Superficial injury of wrist and hand
0.591 0.409 0.000
J09-J18 Influenza and pneumonia
0.591 0.409 0.000
Z04 Examination and observation for other reasons
0.591 0.409 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.590 0.410 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.589 0.411 0.000
R50 Fever of unknown origin
0.589 0.411 0.000
M65-M68 Disorders of synovium and tendon
0.589 0.411 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.589 0.411 0.000
H90-H95 Other disorders of ear
0.589 0.411 0.000
D45 Polycythaemia vera
0.589 0.411 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.588 0.412 0.000
M31 Other necrotising vasculopathies
0.587 0.412 0.000
N13 Obstructive and reflux uropathy
0.587 0.413 0.000
M81 Osteoporosis without pathological fracture
0.587 0.413 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.587 0.413 0.000
M91-M94 Chondropathies
0.587 0.413 0.000
M86-M90 Other osteopathies
0.587 0.413 0.000
M60-M63 Disorders of muscles
0.587 0.413 0.000
M00-M03 Infectious arthropathies
0.587 0.413 0.000
B99-B99 Other infectious diseases
0.587 0.413 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.587 0.413 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.587 0.413 0.000
B65-B83 Helminthiases
0.587 0.413 0.000
B50-B64 Protozoal diseases
0.587 0.413 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.587 0.413 0.000
B15-B19 Viral hepatitis
0.587 0.413 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.587 0.413 0.000
A80-A89 Viral infections of the central nervous system
0.587 0.413 0.000
A75-A79 Rickettsioses
0.587 0.413 0.000
A70-A74 Other diseases caused by chlamydiae
0.587 0.413 0.000
A65-A69 Other spirochaetal diseases
0.587 0.413 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.587 0.413 0.000
A20-A28 Certain zoonotic bacterial diseases
0.587 0.413 0.000
A15-A19 Tuberculosis
0.587 0.413 0.000
S82 Fracture of lower leg, including ankle
0.587 0.413 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.585 0.414 0.000
I08.0 Disorders of both mitral and aortic valves
0.585 0.415 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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