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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7418032
log Bayes Factor = 19.7409
Chromosome 1   position 195,229,043  (GRCh37) Explore rs7418032 on Ensembl!
Variant rs7418032 is part of Cluster X0142

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
M05-M14 Inflammatory polyarthropathies
0.999 0.001 0.000
B95-B98 Bacterial, viral and other infectious agents
0.999 0.001 0.000
Chapter XIV Diseases of the genitourinary system
0.999 0.001 0.000
N17-N19 Renal failure
0.999 0.001 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.998 0.002 0.000
E70-E90 Metabolic disorders
0.998 0.002 0.000
M06 Other rheumatoid arthritis
0.998 0.002 0.000
N17 Acute renal failure
0.997 0.003 0.000
M06.9 Rheumatoid arthritis, unspecified
0.997 0.003 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.997 0.003 0.000
N17.9 Acute renal failure, unspecified
0.996 0.004 0.000
I50 Heart failure
0.996 0.004 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.995 0.005 0.000
I50.0 Congestive heart failure
0.991 0.009 0.000
M20-M25 Other joint disorders
0.989 0.011 0.000
I20-I25 Ischaemic heart diseases
0.987 0.013 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.982 0.018 0.000
D50-D53 Nutritional anaemias
0.981 0.019 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.979 0.021 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.978 0.022 0.000
I05-I09 Chronic rheumatic heart diseases
0.969 0.031 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.969 0.031 0.000
D50 Iron deficiency anaemia
0.967 0.033 0.000
E87.5 Hyperkalaemia
0.967 0.033 0.000
I20 Angina pectoris
0.967 0.033 0.000
E83 Disorders of mineral metabolism
0.964 0.036 0.000
I95 Hypotension
0.963 0.037 0.000
I95.9 Hypotension, unspecified
0.959 0.041 0.000
N18 Chronic renal failure
0.957 0.043 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.955 0.045 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.947 0.053 0.000
N10-N16 Renal tubulo-interstitial diseases
0.945 0.055 0.000
I73 Other peripheral vascular diseases
0.943 0.057 0.000
M50-M54 Other dorsopathies
0.942 0.058 0.000
I51 Complications and ill-defined descriptions of heart disease
0.941 0.059 0.000
I20.9 Angina pectoris, unspecified
0.940 0.060 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.936 0.064 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.930 0.070 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.927 0.073 0.000
M35 Other systemic involvement of connective tissue
0.923 0.077 0.000
D50.8 Other iron deficiency anaemias
0.921 0.079 0.000
I25 Chronic ischaemic heart disease
0.918 0.082 0.000
E20-E35 Disorders of other endocrine glands
0.915 0.085 0.000
M54 Dorsalgia
0.900 0.100 0.000
I08 Multiple valve diseases
0.896 0.104 0.000
E83.1 Disorders of iron metabolism
0.894 0.106 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.892 0.108 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.892 0.108 0.000
D69 Purpura and other haemorrhagic conditions
0.892 0.108 0.000
E78.5 Hyperlipidaemia, unspecified
0.891 0.109 0.000
M54.9 Dorsalgia, unspecified
0.887 0.113 0.000
M80-M85 Disorders of bone density and structure
0.885 0.115 0.000
I73.9 Peripheral vascular disease, unspecified
0.884 0.116 0.000
I34 Nonrheumatic mitral valve disorders
0.883 0.117 0.000
M25 Other joint disorders, not elsewhere classified
0.881 0.119 0.000
D50.9 Iron deficiency anaemia, unspecified
0.878 0.122 0.000
M34 Systemic sclerosis
0.878 0.122 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.875 0.125 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.873 0.127 0.000
A00-A09 Intestinal infectious diseases
0.873 0.127 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.871 0.129 0.000
Chapter VIII Diseases of the ear and mastoid process
0.870 0.130 0.000
N18.4 Chronic kidney disease, stage 4
0.864 0.136 0.000
I20.8 Other forms of angina pectoris
0.861 0.139 0.000
I73.0 Raynaud's syndrome
0.857 0.143 0.000
Chapter VII Diseases of the eye and adnexa
0.855 0.145 0.000
I51.9 Heart disease, unspecified
0.854 0.146 0.000
I10-I15 Hypertensive diseases
0.854 0.146 0.000
E83.4 Disorders of magnesium metabolism
0.852 0.148 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.851 0.149 0.000
N18.5 Chronic kidney disease, stage 5
0.848 0.152 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.845 0.155 0.000
N40-N51 Diseases of male genital organs
0.833 0.167 0.000
E87.7 Fluid overload
0.833 0.167 0.000
I05 Rheumatic mitral valve diseases
0.830 0.170 0.000
I50.1 Left ventricular failure
0.830 0.170 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.830 0.170 0.000
D68 Other coagulation defects
0.829 0.171 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.829 0.171 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.827 0.173 0.000
M07 Psoriatic and enteropathic arthropathies
0.825 0.175 0.000
M10 Gout
0.824 0.176 0.000
Chapter XXII Codes for special purposes
0.823 0.177 0.000
M35.0 Sicca syndrome [Sjogren]
0.823 0.177 0.000
I22 Subsequent myocardial infarction
0.820 0.180 0.000
I34.0 Mitral (valve) insufficiency
0.816 0.184 0.000
S90-S99 Injuries to the ankle and foot
0.811 0.189 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.811 0.189 0.000
I47 Paroxysmal tachycardia
0.808 0.192 0.000
I49 Other cardiac arrhythmias
0.808 0.192 0.000
Chapter X Diseases of the respiratory system
0.807 0.193 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.806 0.194 0.000
M25.5 Pain in joint
0.806 0.194 0.000
I07 Rheumatic tricuspid valve diseases
0.806 0.194 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.803 0.197 0.000
I12 Hypertensive renal disease
0.802 0.198 0.000
I25.5 Ischaemic cardiomyopathy
0.801 0.199 0.000
N00-N08 Glomerular diseases
0.800 0.200 0.000
D51 Vitamin B12 deficiency anaemia
0.799 0.201 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.798 0.202 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.798 0.202 0.000
N18.9 Chronic renal failure, unspecified
0.797 0.203 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.790 0.209 0.000
M33 Dermatopolymyositis
0.789 0.210 0.000
T79-T79 Certain early complications of trauma
0.788 0.212 0.000
M06.3 Rheumatoid nodule
0.786 0.214 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.786 0.214 0.000
E88 Other metabolic disorders
0.785 0.215 0.000
L40-L45 Papulosquamous disorders
0.785 0.215 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.781 0.219 0.000
E83.5 Disorders of calcium metabolism
0.781 0.219 0.000
J90-J94 Other diseases of pleura
0.781 0.219 0.000
H80-H83 Diseases of inner ear
0.780 0.220 0.000
D69.6 Thrombocytopenia, unspecified
0.780 0.220 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.778 0.222 0.000
N20-N23 Urolithiasis
0.776 0.224 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.776 0.224 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.776 0.224 0.000
I72 Other aneurysm
0.775 0.225 0.000
Q50-Q56 Congenital malformations of genital organs
0.774 0.225 0.000
H40-H42 Glaucoma
0.774 0.226 0.000
I35 Nonrheumatic aortic valve disorders
0.773 0.227 0.000
I71 Aortic aneurysm and dissection
0.772 0.228 0.000
M23 Internal derangement of knee
0.771 0.229 0.000
B35-B49 Mycoses
0.771 0.229 0.000
I60-I69 Cerebrovascular diseases
0.771 0.229 0.000
D80-D89 Certain disorders involving the immune mechanism
0.770 0.230 0.000
I37 Pulmonary valve disorders
0.770 0.230 0.000
I36 Nonrheumatic tricuspid valve disorders
0.769 0.231 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.768 0.232 0.000
L40 Psoriasis
0.766 0.234 0.000
M35.3 Polymyalgia rheumatica
0.763 0.237 0.000
T66-T78 Other and unspecified effects of external causes
0.763 0.237 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.763 0.237 0.000
E27 Other disorders of adrenal gland
0.762 0.238 0.000
I51.7 Cardiomegaly
0.762 0.238 0.000
A30-A49 Other bacterial diseases
0.761 0.239 0.000
M84 Disorders of continuity of bone
0.759 0.241 0.000
N18.8 Other chronic renal failure
0.758 0.242 0.000
Q00-Q07 Congenital malformations of the nervous system
0.757 0.243 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.757 0.243 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.756 0.244 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.756 0.244 0.000
I25.1 Atherosclerotic heart disease
0.754 0.246 0.000
I51.4 Myocarditis, unspecified
0.753 0.247 0.000
B15-B19 Viral hepatitis
0.752 0.248 0.000
A08 Viral and other specified intestinal infections
0.751 0.249 0.000
M86-M90 Other osteopathies
0.751 0.249 0.000
N10 Acute tubulo-interstitial nephritis
0.751 0.249 0.000
N42 Other disorders of prostate
0.750 0.250 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.748 0.252 0.000
Chapter XXI Factors influencing health status and contact with health services
0.748 0.252 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.747 0.253 0.000
H65-H75 Diseases of middle ear and mastoid
0.746 0.254 0.000
I08.0 Disorders of both mitral and aortic valves
0.745 0.255 0.000
M05 Seropositive rheumatoid arthritis
0.745 0.255 0.000
S00-S09 Injuries to the head
0.744 0.256 0.000
M22 Disorders of patella
0.744 0.256 0.000
E87.2 Acidosis
0.744 0.256 0.000
E87.6 Hypokalaemia
0.743 0.257 0.000
M11 Other crystal arthropathies
0.742 0.258 0.000
M65-M68 Disorders of synovium and tendon
0.742 0.258 0.000
M34.9 Systemic sclerosis, unspecified
0.741 0.259 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.741 0.259 0.000
M80 Osteoporosis with pathological fracture
0.740 0.260 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.740 0.260 0.000
N11 Chronic tubulo-interstitial nephritis
0.740 0.260 0.000
E50-E64 Other nutritional deficiencies
0.740 0.260 0.000
M54.1 Radiculopathy
0.738 0.262 0.000
M06.0 Seronegative rheumatoid arthritis
0.738 0.262 0.000
I51.6 Cardiovascular disease, unspecified
0.737 0.263 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.737 0.263 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.735 0.265 0.000
M34.1 CR(E)ST syndrome
0.734 0.266 0.000
E29 Testicular dysfunction
0.734 0.266 0.000
L40.9 Psoriasis, unspecified
0.733 0.267 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.733 0.267 0.000
E00-E07 Disorders of thyroid gland
0.732 0.268 0.000
A04 Other bacterial intestinal infections
0.730 0.270 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.729 0.271 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.728 0.272 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.728 0.272 0.000
E87.3 Alkalosis
0.727 0.273 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.727 0.273 0.000
M21 Other acquired deformities of limbs
0.726 0.274 0.000
S92 Fracture of foot, except ankle
0.726 0.274 0.000
M50 Cervical disk disorders
0.726 0.274 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.726 0.274 0.000
N20 Calculus of kidney and ureter
0.724 0.276 0.000
I35.1 Aortic (valve) insufficiency
0.724 0.276 0.000
H81 Disorders of vestibular function
0.724 0.276 0.000
T93 Sequelae of injuries of lower limb
0.723 0.277 0.000
M35.7 Hypermobility syndrome
0.723 0.277 0.000
I42 Cardiomyopathy
0.722 0.278 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.722 0.278 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.720 0.280 0.000
N18.0 End-stage renal disease
0.720 0.280 0.000
I25.3 Aneurysm of heart
0.719 0.281 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I30 Acute pericarditis
0.717 0.283 0.000
B99-B99 Other infectious diseases
0.717 0.283 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.717 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.717 0.283 0.000
B65-B83 Helminthiases
0.717 0.283 0.000
B50-B64 Protozoal diseases
0.717 0.283 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.717 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.717 0.283 0.000
A75-A79 Rickettsioses
0.717 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.717 0.283 0.000
A65-A69 Other spirochaetal diseases
0.717 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.717 0.283 0.000
A15-A19 Tuberculosis
0.717 0.283 0.000
S50-S59 Injuries to the elbow and forearm
0.717 0.283 0.000
M14 Arthropathies in other diseases classified elsewhere
0.716 0.283 0.000
M12 Other specific arthropathies
0.716 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.716 0.283 0.000
M08 Juvenile arthritis
0.716 0.283 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.716 0.284 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.716 0.284 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.716 0.284 0.000
E85 Amyloidosis
0.716 0.284 0.000
E84 Cystic fibrosis
0.716 0.284 0.000
E79 Disorders of purine and pyrimidine metabolism
0.716 0.284 0.000
E77 Disorders of glycoprotein metabolism
0.716 0.284 0.000
E76 Disorders of glycosaminoglycan metabolism
0.716 0.284 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.716 0.284 0.000
E74 Other disorders of carbohydrate metabolism
0.716 0.284 0.000
E73 Lactose intolerance
0.716 0.284 0.000
E72 Other disorders of amino-acid metabolism
0.716 0.284 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.716 0.284 0.000
E70 Disorders of aromatic amino-acid metabolism
0.716 0.284 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.716 0.284 0.000
M06.8 Other specified rheumatoid arthritis
0.716 0.284 0.000
M06.4 Inflammatory polyarthropathy
0.716 0.284 0.000
M06.2 Rheumatoid bursitis
0.716 0.284 0.000
M06.1 Adult-onset Still's disease
0.716 0.284 0.000
N41 Inflammatory diseases of prostate
0.716 0.284 0.000
H40 Glaucoma
0.715 0.285 0.000
N17.8 Other acute renal failure
0.715 0.285 0.000
N17.2 Acute renal failure with medullary necrosis
0.715 0.285 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.715 0.285 0.000
N17.0 Acute renal failure with tubular necrosis
0.715 0.285 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.715 0.285 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.715 0.285 0.000
D55-D59 Haemolytic anaemias
0.715 0.285 0.000
M91-M94 Chondropathies
0.714 0.285 0.000
M00-M03 Infectious arthropathies
0.714 0.286 0.000
O85-O92 Complications predominantly related to the puerperium
0.713 0.287 0.000
I12.0 Hypertensive renal disease with renal failure
0.713 0.287 0.000
I20.1 Angina pectoris with documented spasm
0.712 0.288 0.000
M25.57 Pain in joint (Ankle and foot)
0.712 0.288 0.000
M40-M43 Deforming dorsopathies
0.711 0.289 0.000
H10-H13 Disorders of conjunctiva
0.711 0.289 0.000
S20-S29 Injuries to the thorax
0.710 0.290 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.710 0.290 0.000
B07 Viral warts
0.709 0.291 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.709 0.291 0.000
M32 Systemic lupus erythematosus
0.709 0.291 0.000
M30 Polyarteritis nodosa and related conditions
0.709 0.291 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.709 0.291 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.708 0.292 0.000
I33 Acute and subacute endocarditis
0.708 0.292 0.000
I23 Certain current complications following acute myocardial infarction
0.708 0.292 0.000
M31 Other necrotising vasculopathies
0.708 0.292 0.000
O36 Maternal care for other known or suspected foetal problems
0.707 0.293 0.000
I12.9 Hypertensive renal disease without renal failure
0.707 0.293 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.704 0.296 0.000
E87.4 Mixed disorder of acid-base balance
0.704 0.296 0.000
D53 Other nutritional anaemias
0.704 0.296 0.000
E23 Hypofunction and other disorders of pituitary gland
0.704 0.296 0.000
M23.8 Other internal derangements of knee
0.703 0.297 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.703 0.297 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.702 0.298 0.000
I99 Other and unspecified disorders of circulatory system
0.702 0.298 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.701 0.299 0.000
M07.3 Other psoriatic arthropathies
0.701 0.299 0.000
M53 Other dorsopathies, not elsewhere classified
0.701 0.299 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.701 0.299 0.000
H40.9 Glaucoma, unspecified
0.701 0.299 0.000
S70-S79 Injuries to the hip and thigh
0.700 0.300 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.699 0.301 0.000
M10.9 Gout, unspecified
0.698 0.302 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.698 0.302 0.000
I50.9 Heart failure, unspecified
0.698 0.302 0.000
I44 Atrioventricular and left bundle-branch block
0.697 0.303 0.000
I46 Cardiac arrest
0.696 0.304 0.000
I09 Other rheumatic heart diseases
0.695 0.305 0.000
I06 Rheumatic aortic valve diseases
0.695 0.305 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.695 0.305 0.000
I11 Hypertensive heart disease
0.694 0.306 0.000
N46 Male infertility
0.694 0.306 0.000
Chapter XX External causes of morbidity and mortality
0.694 0.306 0.000
J90 Pleural effusion, not elsewhere classified
0.694 0.306 0.000
D50.1 Sideropenic dysphagia
0.693 0.307 0.000
I69 Sequelae of cerebrovascular disease
0.693 0.307 0.000
I05.0 Mitral stenosis
0.691 0.308 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.691 0.309 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.691 0.309 0.000
E83.8 Other disorders of mineral metabolism
0.691 0.309 0.000
E83.2 Disorders of zinc metabolism
0.691 0.309 0.000
E83.0 Disorders of copper metabolism
0.691 0.309 0.000
I95.8 Other hypotension
0.690 0.310 0.000
I95.0 Idiopathic hypotension
0.690 0.310 0.000
D69.5 Secondary thrombocytopenia
0.690 0.310 0.000
E40-E46 Malnutrition
0.690 0.310 0.000
A80-A89 Viral infections of the central nervous system
0.688 0.311 0.000
S40-S49 Injuries to the shoulder and upper arm
0.689 0.311 0.000
I07.1 Tricuspid insufficiency
0.688 0.312 0.000
D68.8 Other specified coagulation defects
0.688 0.312 0.000
E10-E14 Diabetes mellitus
0.687 0.313 0.000
N18.1 Chronic kidney disease, stage 1
0.686 0.314 0.000
I60 Subarachnoid haemorrhage
0.685 0.315 0.000
B25-B34 Other viral diseases
0.685 0.315 0.000
D67 Hereditary factor IX deficiency
0.685 0.315 0.000
D66 Hereditary factor VIII deficiency
0.685 0.315 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.685 0.315 0.000
I85 Oesophageal varices
0.684 0.316 0.000
N19 Unspecified renal failure
0.684 0.316 0.000
S10-S19 Injuries to the neck
0.683 0.317 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.683 0.317 0.000
E78.2 Mixed hyperlipidaemia
0.681 0.318 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.681 0.319 0.000
I81 Portal vein thrombosis
0.681 0.319 0.000
I31 Other diseases of pericardium
0.679 0.321 0.000
T33-T35 Frostbite
0.679 0.321 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.679 0.321 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.679 0.321 0.000
T00-T07 Injuries involving multiple body regions
0.679 0.321 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.678 0.322 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.678 0.322 0.000
N15 Other renal tubulo-interstitial diseases
0.678 0.322 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.678 0.322 0.000
H81.0 Meniere's disease
0.677 0.323 0.000
I38 Endocarditis, valve unspecified
0.677 0.323 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.676 0.324 0.000
I73.8 Other specified peripheral vascular diseases
0.676 0.324 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.676 0.324 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.675 0.324 0.000
N50 Other disorders of male genital organs
0.675 0.325 0.000
I51.5 Myocardial degeneration
0.674 0.325 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.674 0.325 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.674 0.325 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.674 0.325 0.000
I51.0 Cardiac septal defect, acquired
0.674 0.325 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.674 0.325 0.000
N20.1 Calculus of ureter
0.674 0.326 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.672 0.328 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.672 0.328 0.000
M25.50 Pain in joint (Multiple sites)
0.672 0.328 0.000
I71.0 Dissection of aorta [any part]
0.672 0.328 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.671 0.329 0.000
Q80-Q89 Other congenital malformations
0.671 0.329 0.000
Q35-Q37 Cleft lip and cleft palate
0.671 0.329 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.671 0.329 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.671 0.329 0.000
A04.8 Other specified bacterial intestinal infections
0.671 0.329 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.670 0.330 0.000
J93 Pneumothorax
0.669 0.331 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.669 0.331 0.000
E78.8 Other disorders of lipoprotein metabolism
0.665 0.335 0.000
E78.6 Lipoprotein deficiency
0.665 0.335 0.000
E78.4 Other hyperlipidaemia
0.665 0.335 0.000
E78.3 Hyperchylomicronaemia
0.665 0.335 0.000
E78.1 Pure hyperglyceridaemia
0.665 0.335 0.000
I49.4 Other and unspecified premature depolarisation
0.664 0.336 0.000
D52 Folate deficiency anaemia
0.663 0.337 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.663 0.337 0.000
I05.1 Rheumatic mitral insufficiency
0.662 0.338 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.662 0.338 0.000
M35.8 Other specified systemic involvement of connective tissue
0.662 0.338 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.662 0.338 0.000
M35.5 Multifocal fibrosclerosis
0.662 0.338 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.662 0.338 0.000
M35.2 Behcet's disease
0.662 0.338 0.000
M35.1 Other overlap syndromes
0.662 0.338 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.661 0.339 0.000
M24 Other specific joint derangements
0.661 0.339 0.000
H65 Nonsuppurative otitis media
0.660 0.340 0.000
M54.4 Lumbago with sciatica
0.660 0.340 0.000
T91 Sequelae of injuries of neck and trunk
0.659 0.341 0.000
I25.6 Silent myocardial ischaemia
0.658 0.342 0.000
I25.4 Coronary artery aneurysm
0.658 0.342 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.658 0.342 0.000
M25.8 Other specified joint disorders
0.658 0.342 0.000
I47.1 Supraventricular tachycardia
0.658 0.342 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.656 0.344 0.000
E34 Other endocrine disorders
0.656 0.344 0.000
E32 Diseases of thymus
0.656 0.344 0.000
E31 Polyglandular dysfunction
0.656 0.344 0.000
E30 Disorders of puberty, not elsewhere classified
0.656 0.344 0.000
E26 Hyperaldosteronism
0.656 0.344 0.000
E25 Adrenogenital disorders
0.656 0.344 0.000
E24 Cushing's syndrome
0.656 0.344 0.000
E20 Hypoparathyroidism
0.656 0.344 0.000
Q60-Q64 Congenital malformations of the urinary system
0.655 0.345 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.654 0.346 0.000
T31 Burns classified according to extent of body surface involved
0.653 0.347 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.652 0.348 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.652 0.348 0.000
Z29 Need for other prophylactic measures
0.651 0.349 0.000
J91 Pleural effusion in conditions classified elsewhere
0.651 0.349 0.000
L40.5 Arthropathic psoriasis
0.650 0.350 0.000
E28 Ovarian dysfunction
0.650 0.350 0.000
S02 Fracture of skull and facial bones
0.649 0.351 0.000
H55-H59 Other disorders of eye and adnexa
0.649 0.351 0.000
I49.3 Ventricular premature depolarisation
0.649 0.351 0.000
M25.9 Joint disorder, unspecified
0.649 0.351 0.000
I70 Atherosclerosis
0.649 0.351 0.000
I77 Other disorders of arteries and arterioles
0.649 0.351 0.000
D68.9 Coagulation defect, unspecified
0.647 0.353 0.000
M54.6 Pain in thoracic spine
0.647 0.353 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.647 0.353 0.000
M33.2 Polymyositis
0.647 0.353 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.646 0.354 0.000
M54.8 Other dorsalgia
0.646 0.354 0.000
M54.0 Panniculitis affecting regions of neck and back
0.646 0.354 0.000
I49.5 Sick sinus syndrome
0.645 0.355 0.000
E22 Hyperfunction of pituitary gland
0.643 0.356 0.000
H73 Other disorders of tympanic membrane
0.643 0.357 0.000
E04 Other non-toxic goitre
0.643 0.357 0.000
I08.9 Multiple valve disease, unspecified
0.643 0.357 0.000
I08.8 Other multiple valve diseases
0.643 0.357 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.643 0.357 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.643 0.357 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.643 0.357 0.000
O44 Placenta praevia
0.641 0.358 0.000
O48 Prolonged pregnancy
0.641 0.359 0.000
I78 Diseases of capillaries
0.640 0.359 0.000
S92.3 Fracture of metatarsal bone
0.640 0.360 0.000
Chapter VI Diseases of the nervous system
0.640 0.360 0.000
D69.9 Haemorrhagic condition, unspecified
0.639 0.361 0.000
D69.8 Other specified haemorrhagic conditions
0.639 0.361 0.000
D69.4 Other primary thrombocytopenia
0.639 0.361 0.000
D69.2 Other nonthrombocytopenic purpura
0.639 0.361 0.000
D69.1 Qualitative platelet defects
0.639 0.361 0.000
D69.0 Allergic purpura
0.639 0.361 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.639 0.361 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.639 0.361 0.000
N42.0 Calculus of prostate
0.638 0.362 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.638 0.362 0.000
M23.5 Chronic instability of knee
0.637 0.363 0.000
J86 Pyothorax
0.637 0.363 0.000
D68.2 Hereditary deficiency of other clotting factors
0.637 0.363 0.000
O40 Polyhydramnios
0.637 0.363 0.000
I72.8 Aneurysm of other specified arteries
0.636 0.364 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.636 0.364 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.636 0.364 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.636 0.364 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.636 0.364 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.636 0.364 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.636 0.364 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.636 0.364 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.636 0.364 0.000
J92 Pleural plaque
0.636 0.364 0.000
M83 Adult osteomalacia
0.635 0.365 0.000
M82 Osteoporosis in diseases classified elsewhere
0.635 0.365 0.000
Z72 Problems related to lifestyle
0.634 0.366 0.000
M06.34 Rheumatoid nodule (Hand)
0.634 0.366 0.000
O16 Unspecified maternal hypertension
0.634 0.366 0.000
N99-N99 Other disorders of the genitourinary system
0.634 0.366 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.633 0.367 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.633 0.367 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.633 0.367 0.000
I87 Other disorders of veins
0.633 0.367 0.000
M81 Osteoporosis without pathological fracture
0.632 0.368 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.632 0.368 0.000
M25.3 Other instability of joint
0.632 0.368 0.000
M25.2 Flail joint
0.632 0.368 0.000
M25.1 Fistula of joint
0.632 0.368 0.000
M25.0 Haemarthrosis
0.632 0.368 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.631 0.369 0.000
D86 Sarcoidosis
0.631 0.369 0.000
M34.8 Other forms of systemic sclerosis
0.629 0.370 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.629 0.370 0.000
M34.0 Progressive systemic sclerosis
0.629 0.370 0.000
Q05 Spina bifida
0.629 0.371 0.000
S01 Open wound of head
0.629 0.371 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.626 0.374 0.000
A07 Other protozoal intestinal diseases
0.626 0.374 0.000
A06 Amoebiasis
0.626 0.374 0.000
A05 Other bacterial foodborne intoxications
0.626 0.374 0.000
A03 Shigellosis
0.626 0.374 0.000
A02 Other Salmonella infections
0.626 0.374 0.000
A01 Typhoid and paratyphoid fevers
0.626 0.374 0.000
A00 Cholera
0.626 0.374 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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