TreeWAS – Variant ID: rs74349453

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
# Top node	1.000	0.000
Chapter X Diseases of the respiratory system	1.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000
M20-M25 Other joint disorders	1.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000
I25 Chronic ischaemic heart disease	0.999	0.001
J40-J47 Chronic lower respiratory diseases	0.998	0.002
Chapter V Mental and behavioural disorders	0.996	0.004
M20 Acquired deformities of fingers and toes	0.996	0.004
I25.2 Old myocardial infarction	0.995	0.005
M15-M19 Arthrosis	0.994	0.006
J45 Asthma	0.990	0.010
I25.8 Other forms of chronic ischaemic heart disease	0.989	0.011
J30-J39 Other diseases of upper respiratory tract	0.984	0.016
J45.9 Asthma, unspecified	0.984	0.016
Chapter II Neoplasms	0.975	0.025
M17 Gonarthrosis [arthrosis of knee]	0.970	0.030
Chapter I Certain infectious and parasitic diseases	0.970	0.030
M23 Internal derangement of knee	0.965	0.035
Chapter VIII Diseases of the ear and mastoid process	0.957	0.043
F40-F48 Neurotic, stress-related and somatoform disorders	0.956	0.044
I30-I52 Other forms of heart disease	0.955	0.045
Chapter XX External causes of morbidity and mortality	0.954	0.046
M20.1 Hallux valgus (acquired)	0.951	0.049
Chapter VII Diseases of the eye and adnexa	0.949	0.051
Chapter IV Endocrine, nutritional and metabolic diseases	0.948	0.052
M20.5 Other deformities of toe(s) (acquired)	0.940	0.060
J33 Nasal polyp	0.929	0.071
M17.1 Other primary gonarthrosis	0.926	0.074
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.924	0.076
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.923	0.077
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.923	0.077
E10-E14 Diabetes mellitus	0.922	0.078
F41 Other anxiety disorders	0.921	0.079
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.920	0.080
M25 Other joint disorders, not elsewhere classified	0.912	0.088
J33.9 Nasal polyp, unspecified	0.905	0.095
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.905	0.095
R13 Dysphagia	0.904	0.096
J47 Bronchiectasis	0.903	0.097
F41.2 Mixed anxiety and depressive disorder	0.903	0.097
I24 Other acute ischaemic heart diseases	0.900	0.100
M20.6 Acquired deformity of toe(s), unspecified	0.899	0.101
E11 Non-insulin-dependent diabetes mellitus	0.897	0.103
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.896	0.104
R18 Ascites	0.895	0.105
M17.9 Gonarthrosis, unspecified	0.892	0.108
J95-J99 Other diseases of the respiratory system	0.890	0.110
E11.9 Without complications	0.888	0.112
M18 Arthrosis of first carpometacarpal joint	0.887	0.113
M22 Disorders of patella	0.885	0.115
J30 Vasomotor and allergic rhinitis	0.878	0.122
M19 Other arthrosis	0.877	0.123
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.874	0.126
M23.8 Other internal derangements of knee	0.868	0.132
E20-E35 Disorders of other endocrine glands	0.867	0.133
I70-I79 Diseases of arteries, arterioles and capillaries	0.859	0.141
M23.3 Other meniscus derangements	0.859	0.141
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.856	0.144
Chapter VI Diseases of the nervous system	0.853	0.147
M20.4 Other hammer toe(s) (acquired)	0.851	0.149
D10-D36 Benign neoplasms	0.848	0.152
M25.7 Osteophyte	0.847	0.153
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.847	0.153
J80-J84 Other respiratory diseases principally affecting the interstitium	0.847	0.153
I50 Heart failure	0.846	0.154
I22 Subsequent myocardial infarction	0.844	0.156
H90-H95 Other disorders of ear	0.844	0.156
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.842	0.158
R15 Faecal incontinence	0.840	0.160
A00-A09 Intestinal infectious diseases	0.840	0.160
C15-C26 Malignant neoplasms of digestive organs	0.839	0.161
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.837	0.163
H00 Hordeolum and chalazion	0.833	0.167
A30-A49 Other bacterial diseases	0.832	0.168
Y43 Primarily systemic agents	0.832	0.168
I21 Acute myocardial infarction	0.829	0.171
F00-F09 Organic, including symptomatic, mental disorders	0.829	0.171
J40 Bronchitis, not specified as acute or chronic	0.828	0.172
I46 Cardiac arrest	0.827	0.173
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.824	0.176
M65-M68 Disorders of synovium and tendon	0.822	0.178
I44 Atrioventricular and left bundle-branch block	0.821	0.179
I35 Nonrheumatic aortic valve disorders	0.817	0.183
J20-J22 Other acute lower respiratory infections	0.816	0.184
F30-F39 Mood [affective] disorders	0.813	0.187
H80-H83 Diseases of inner ear	0.813	0.187
J98 Other respiratory disorders	0.811	0.189
E10 Insulin-dependent diabetes mellitus	0.811	0.189
J42 Unspecified chronic bronchitis	0.811	0.189
M19.9 Arthrosis, unspecified	0.808	0.192
I95-I99 Other and unspecified disorders of the circulatory system	0.807	0.193
M50-M54 Other dorsopathies	0.807	0.193
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.804	0.196
M22.4 Chondromalacia patellae	0.802	0.198
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.800	0.200
M20.3 Other deformity of hallux (acquired)	0.798	0.202
I25.9 Chronic ischaemic heart disease, unspecified	0.798	0.202
B25-B34 Other viral diseases	0.797	0.203
T36-T50 Poisoning by drugs, medicaments and biological substances	0.794	0.206
H01 Other inflammation of eyelid	0.793	0.207
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.790	0.210
M19.99 Arthrosis, unspecified (Site unspecified)	0.788	0.212
M05-M14 Inflammatory polyarthropathies	0.788	0.212
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.782	0.218
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.782	0.218
C79 Secondary malignant neoplasm of other sites	0.781	0.219
H00.1 Chalazion	0.781	0.219
B20-B24 Human immunodeficiency virus [HIV] disease	0.781	0.219
H65-H75 Diseases of middle ear and mastoid	0.780	0.220
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.779	0.221
J32 Chronic sinusitis	0.778	0.222
I21.9 Acute myocardial infarction, unspecified	0.777	0.223
D22 Melanocytic naevi	0.774	0.226
M80-M85 Disorders of bone density and structure	0.774	0.226
Y57 Other and unspecified drugs and medicaments	0.771	0.229
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.768	0.232
H55-H59 Other disorders of eye and adnexa	0.766	0.234
Y43.3 Other antineoplastic drugs	0.766	0.234
I24.8 Other forms of acute ischaemic heart disease	0.766	0.234
F80-F89 Disorders of psychological development	0.765	0.235
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.764	0.236
I74 Arterial embolism and thrombosis	0.762	0.238
M23.2 Derangement of meniscus due to old tear or injury	0.761	0.239
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.760	0.239
J39 Other diseases of upper respiratory tract	0.760	0.240
J45.0 Predominantly allergic asthma	0.760	0.240
M91-M94 Chondropathies	0.759	0.241
D00-D09 In situ neoplasms	0.758	0.242
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.758	0.242
I50.1 Left ventricular failure	0.758	0.242
Y44 Agents primarily affecting blood constituents	0.753	0.247
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.752	0.248
E00-E07 Disorders of thyroid gland	0.750	0.250
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.750	0.250
J84 Other interstitial pulmonary diseases	0.749	0.251
E27 Other disorders of adrenal gland	0.749	0.251
H60-H62 Diseases of external ear	0.749	0.251
J43 Emphysema	0.748	0.252
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.747	0.253
B90-B94 Sequelae of infectious and parasitic diseases	0.747	0.253
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.746	0.254
I46.9 Cardiac arrest, unspecified	0.745	0.255
F10 Mental and behavioural disorders due to use of alcohol	0.744	0.256
X40-X49 Accidental poisoning by and exposure to noxious substances	0.742	0.258
J30.1 Allergic rhinitis due to pollen	0.742	0.258
M18.1 Other primary arthrosis of first carpometacarpal joint	0.741	0.259
H10-H13 Disorders of conjunctiva	0.741	0.259
I51 Complications and ill-defined descriptions of heart disease	0.741	0.259
D25 Leiomyoma of uterus	0.741	0.259
J30.4 Allergic rhinitis, unspecified	0.740	0.260
J98.1 Pulmonary collapse	0.740	0.260
M86-M90 Other osteopathies	0.739	0.261
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.737	0.263
G90-G99 Other disorders of the nervous system	0.736	0.264
F60-F69 Disorders of adult personality and behaviour	0.736	0.264
R12 Heartburn	0.735	0.265
A41 Other septicaemia	0.734	0.266
M25.76 Osteophyte (Lower leg)	0.733	0.267
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.732	0.268
F29 Unspecified nonorganic psychosis	0.730	0.270
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.729	0.271
J60-J70 Lung diseases due to external agents	0.728	0.272
Chapter XXII Codes for special purposes	0.728	0.272
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.727	0.273
M25.8 Other specified joint disorders	0.727	0.273
J38.7 Other diseases of larynx	0.727	0.273
I71 Aortic aneurysm and dissection	0.726	0.274
A50-A64 Infections with a predominantly sexual mode of transmission	0.726	0.274
H92 Otalgia and effusion of ear	0.725	0.275
F40 Phobic anxiety disorders	0.723	0.277
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.723	0.277
M25.74 Osteophyte (Hand)	0.722	0.278
M23.4 Loose body in knee	0.722	0.278
Y40 Systemic antibiotics	0.721	0.279
C83 Diffuse non-Hodgkin's lymphoma	0.719	0.281
F99-F99 Unspecified mental disorder	0.719	0.281
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.718	0.282
I22.0 Subsequent myocardial infarction of anterior wall	0.718	0.282
H04 Disorders of lachrymal system	0.718	0.282
M60-M63 Disorders of muscles	0.717	0.283
M00-M03 Infectious arthropathies	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.717	0.283
M34 Systemic sclerosis	0.717	0.283
M33 Dermatopolymyositis	0.717	0.283
M32 Systemic lupus erythematosus	0.717	0.283
M30 Polyarteritis nodosa and related conditions	0.717	0.283
I23 Certain current complications following acute myocardial infarction	0.717	0.283
I25.6 Silent myocardial ischaemia	0.717	0.283
I25.5 Ischaemic cardiomyopathy	0.717	0.283
I25.4 Coronary artery aneurysm	0.717	0.283
I25.3 Aneurysm of heart	0.717	0.283
I25.0 Atherosclerotic cardiovascular disease, so described	0.717	0.283
J41 Simple and mucopurulent chronic bronchitis	0.715	0.284
I35.1 Aortic (valve) insufficiency	0.715	0.285
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.714	0.286
F70-F79 Mental retardation	0.714	0.286
M20.0 Deformity of finger(s)	0.714	0.286
X60-X84 Intentional self-harm	0.714	0.286
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.714	0.286
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.713	0.287
H01.0 Blepharitis	0.713	0.287
M15 Polyarthrosis	0.713	0.287
D37-D48 Neoplasms of uncertain or unknown behaviour	0.712	0.288
G20-G26 Extrapyramidal and movement disorders	0.712	0.288
M21 Other acquired deformities of limbs	0.712	0.288
I45 Other conduction disorders	0.711	0.289
J45.8 Mixed asthma	0.710	0.290
J45.1 Nonallergic asthma	0.710	0.290
S50-S59 Injuries to the elbow and forearm	0.709	0.291
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.709	0.291
F45 Somatoform disorders	0.708	0.292
J37 Chronic laryngitis and laryngotracheitis	0.706	0.294
J35 Chronic diseases of tonsils and adenoids	0.704	0.296
I44.1 Atrioventricular block, second degree	0.704	0.296
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.703	0.297
M24 Other specific joint derangements	0.703	0.297
M25.4 Effusion of joint	0.703	0.297
M67 Other disorders of synovium and tendon	0.701	0.299
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.700	0.300
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.699	0.301
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.699	0.301
C40-C41 Malignant neoplasms of bone and articular cartilage	0.699	0.301
H72 Perforation of tympanic membrane	0.699	0.301
M19.91 Arthrosis, unspecified (Shoulder region)	0.697	0.303
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.697	0.303
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.697	0.303
E29 Testicular dysfunction	0.697	0.303
G70-G73 Diseases of myoneural junction and muscle	0.696	0.304
F20 Schizophrenia	0.696	0.304
M17.5 Other secondary gonarthrosis	0.695	0.304
M17.4 Other secondary gonarthrosis, bilateral	0.695	0.304
M17.3 Other posttraumatic gonarthrosis	0.695	0.304
M17.2 Posttraumatic gonarthrosis, bilateral	0.695	0.304
B99-B99 Other infectious diseases	0.695	0.304
B85-B89 Pediculosis, acariasis and other infestations	0.695	0.304
B65-B83 Helminthiases	0.695	0.304
B50-B64 Protozoal diseases	0.695	0.304
B15-B19 Viral hepatitis	0.695	0.304
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.695	0.304
A80-A89 Viral infections of the central nervous system	0.695	0.304
A75-A79 Rickettsioses	0.695	0.304
A70-A74 Other diseases caused by chlamydiae	0.695	0.304
A65-A69 Other spirochaetal diseases	0.695	0.304
A20-A28 Certain zoonotic bacterial diseases	0.695	0.304
A15-A19 Tuberculosis	0.695	0.304
H25-H28 Disorders of lens	0.695	0.305
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.695	0.305
S70-S79 Injuries to the hip and thigh	0.694	0.305
I38 Endocarditis, valve unspecified	0.694	0.306
C81 Hodgkin's disease	0.694	0.306
I99 Other and unspecified disorders of circulatory system	0.694	0.306
C20 Malignant neoplasm of rectum	0.694	0.306
C23 Malignant neoplasm of gallbladder	0.693	0.306
M23.9 Internal derangement of knee, unspecified	0.692	0.308
M23.6 Other spontaneous disruption of ligament(s) of knee	0.692	0.308
M23.5 Chronic instability of knee	0.692	0.308
M23.1 Discoid meniscus (congenital)	0.692	0.308
M23.0 Cystic meniscus	0.692	0.308
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.692	0.308
I44.2 Atrioventricular block, complete	0.690	0.310
W00-W19 Falls	0.689	0.310
V20-V29 Motorcycle rider injured in transport accident	0.689	0.311
D35 Benign neoplasm of other and unspecified endocrine glands	0.689	0.311
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.688	0.311
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.688	0.312
B35-B49 Mycoses	0.686	0.314
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.686	0.314
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.686	0.314
F48 Other neurotic disorders	0.686	0.314
F44 Dissociative [conversion] disorders	0.686	0.314
F42 Obsessive-compulsive disorder	0.686	0.314
M31 Other necrotising vasculopathies	0.685	0.315
I52 Other heart disorders in diseases classified elsewhere	0.685	0.315
I48 Atrial fibrillation and flutter	0.685	0.315
I43 Cardiomyopathy in diseases classified elsewhere	0.685	0.315
I41 Myocarditis in diseases classified elsewhere	0.685	0.315
I40 Acute myocarditis	0.685	0.315
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.685	0.315
I37 Pulmonary valve disorders	0.685	0.315
I36 Nonrheumatic tricuspid valve disorders	0.685	0.315
I33 Acute and subacute endocarditis	0.685	0.315
I32 Pericarditis in diseases classified elsewhere	0.685	0.315
I30 Acute pericarditis	0.685	0.315
J00-J06 Acute upper respiratory infections	0.685	0.315
A08 Viral and other specified intestinal infections	0.685	0.315
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.684	0.316
Y35-Y36 Legal intervention and operations of war	0.684	0.316
Y10-Y34 Event of undetermined intent	0.684	0.316
Y00-Y09 Assault	0.684	0.316
X85-X99 Assault	0.684	0.316
X58-X59 Accidental exposure to other and unspecified factors	0.684	0.316
X50-X57 Overexertion, travel and privation	0.684	0.316
X30-X39 Exposure to forces of nature	0.684	0.316
X20-X29 Contact with venomous animals and plants	0.684	0.316
X10-X19 Contact with heat and hot substances	0.684	0.316
X00-X09 Exposure to smoke, fire and flames	0.684	0.316
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.684	0.316
W75-W84 Other accidental threats to breathing	0.684	0.316
W65-W74 Accidental drowning and submersion	0.684	0.316
W50-W64 Exposure to animate mechanical forces	0.684	0.316
V98-V99 Other and unspecified transport accidents	0.684	0.316
V95-V97 Air and space transport accidents	0.684	0.316
V90-V94 Water transport accidents	0.684	0.316
V80-V89 Other land transport accidents	0.684	0.316
V70-V79 Bus occupant injured in transport accident	0.684	0.316
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.684	0.316
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.684	0.316
V40-V49 Car occupant injured in transport accident	0.684	0.316
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.684	0.316
V01-V09 Pedestrian injured in transport accident	0.684	0.316
J22 Unspecified acute lower respiratory infection	0.683	0.317
C92 Myeloid leukaemia	0.683	0.317
I82 Other venous embolism and thrombosis	0.683	0.317
E10.1 With ketoacidosis	0.683	0.317
F43 Reaction to severe stress, and adjustment disorders	0.681	0.319
S20-S29 Injuries to the thorax	0.680	0.319
H46-H48 Disorders of optic nerve and visual pathways	0.680	0.319
D13.1 Stomach	0.680	0.320
E40-E46 Malnutrition	0.679	0.320
F05 Delirium, not induced by alcohol and other psychoactive substances	0.679	0.321
I05-I09 Chronic rheumatic heart diseases	0.678	0.322
I89.0 Lymphoedema, not elsewhere classified	0.678	0.322
H93 Other disorders of ear, not elsewhere classified	0.676	0.323
B95-B98 Bacterial, viral and other infectious agents	0.676	0.324
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.676	0.324
J46 Status asthmaticus	0.675	0.325
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.674	0.326
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.674	0.326
B34 Viral infection of unspecified site	0.673	0.327
D22.0 Melanocytic naevi of lip	0.670	0.330
I84 Haemorrhoids	0.670	0.330
J84.1 Other interstitial pulmonary diseases with fibrosis	0.669	0.331
M16 Coxarthrosis [arthrosis of hip]	0.669	0.331
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.668	0.332
F22 Persistent delusional disorders	0.668	0.332
J98.0 Diseases of bronchus, not elsewhere classified	0.667	0.333
M25.77 Osteophyte (Ankle and foot)	0.667	0.333
C80 Malignant neoplasm without specification of site	0.667	0.333
I50.9 Heart failure, unspecified	0.667	0.333
I34 Nonrheumatic mitral valve disorders	0.666	0.334
J33.1 Polypoid sinus degeneration	0.666	0.334
D30 Benign neoplasm of urinary organs	0.664	0.336
Q20-Q28 Congenital malformations of the circulatory system	0.663	0.337
M10 Gout	0.663	0.337
Y59 Other and unspecified vaccines and biological substances	0.663	0.337
Y58 Bacterial vaccines	0.663	0.337
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.663	0.337
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.663	0.337
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.663	0.337
Y53 Agents primarily affecting the gastro-intestinal system	0.663	0.337
Y52 Agents primarily affecting the cardiovascular system	0.663	0.337
Y51 Drugs primarily affecting the autonomic nervous system	0.663	0.337
Y50 Central nervous system stimulants, not elsewhere classified	0.663	0.337
Y49 Psychotropic drugs, not elsewhere classified	0.663	0.337
Y48 Anaesthetics and therapeutic gases	0.663	0.337
Y47 Sedatives, hypnotics and antianxiety drugs	0.663	0.337
Y46 Antiepileptics and anti-Parkinsonism drugs	0.663	0.337
Y41 Other systemic anti-infectives and antiparasitics	0.663	0.337
M23.30 Other meniscus derangements (Multiple sites)	0.662	0.338
R95-R99 Ill-defined and unknown causes of mortality	0.662	0.338
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.662	0.338
M50 Cervical disk disorders	0.662	0.338
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.662	0.338
C95 Leukaemia of unspecified cell type	0.662	0.338
C94 Other leukaemias of specified cell type	0.662	0.338
C93 Monocytic leukaemia	0.662	0.338
C88 Malignant immunoproliferative diseases	0.662	0.338
C86 Other specified types of T/NK-cell lymphoma	0.662	0.338
C84 Peripheral and cutaneous T-cell lymphomas	0.662	0.338
H90 Conductive and sensorineural hearing loss	0.662	0.338
E13 Other specified diabetes mellitus	0.661	0.339
E12 Malnutrition-related diabetes mellitus	0.661	0.339
F41.8 Other specified anxiety disorders	0.660	0.340
F41.3 Other mixed anxiety disorders	0.660	0.340
F41.1 Generalised anxiety disorder	0.660	0.340
H20 Iridocyclitis	0.660	0.340
M40-M43 Deforming dorsopathies	0.660	0.340
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.658	0.341
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.658	0.342
F10.2 Dependence syndrome	0.658	0.342
J38.4 Oedema of larynx	0.658	0.342
V10-V19 Pedal cyclist injured in transport accident	0.657	0.343
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.657	0.343
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.657	0.343
J90-J94 Other diseases of pleura	0.655	0.345
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.655	0.345
M45-M49 Spondylopathies	0.655	0.345
W20-W49 Exposure to inanimate mechanical forces	0.654	0.346
D10 Benign neoplasm of mouth and pharynx	0.654	0.346
M25.9 Joint disorder, unspecified	0.654	0.346
M25.6 Stiffness of joint, not elsewhere classified	0.654	0.346
M25.3 Other instability of joint	0.654	0.346
M25.2 Flail joint	0.654	0.346
M25.1 Fistula of joint	0.654	0.346
M25.0 Haemarthrosis	0.654	0.346
I31 Other diseases of pericardium	0.653	0.346
F00 Dementia in Alzheimer's disease	0.653	0.346
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.652	0.348
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.651	0.349
D22.7 Melanocytic naevi of lower limb, including hip	0.651	0.349
H83 Other diseases of inner ear	0.651	0.349
H81 Disorders of vestibular function	0.651	0.349
C19 Malignant neoplasm of rectosigmoid junction	0.651	0.349
M51 Other intervertebral disk disorders	0.650	0.350
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.649	0.351
H05 Disorders of orbit	0.649	0.351
H03 Disorders of eyelid in diseases classified elsewhere	0.649	0.351
I77 Other disorders of arteries and arterioles	0.649	0.351
Y60-Y69 Misadventures to patients during surgical and medical care	0.648	0.352
C91 Lymphoid leukaemia	0.648	0.352
H43-H45 Disorders of vitreous body and globe	0.647	0.353
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.647	0.353
J34 Other disorders of nose and nasal sinuses	0.646	0.354
E23 Hypofunction and other disorders of pituitary gland	0.646	0.354
I24.1 Dressler's syndrome	0.645	0.355
B24 Unspecified human immunodeficiency virus [HIV] disease	0.645	0.355
E11.8 With unspecified complications	0.643	0.356
E11.7 With multiple complications	0.643	0.356
E11.6 With other specified complications	0.643	0.356
E11.2 With renal complications	0.643	0.356
E11.1 With ketoacidosis	0.643	0.356
E11.0 With coma	0.643	0.356
T79-T79 Certain early complications of trauma	0.643	0.357
T33-T35 Frostbite	0.643	0.357
T26-T28 Burns and corrosions confined to eye and internal organs	0.643	0.357
T20-T25 Burns and corrosions of external body surface, specified by site	0.643	0.357
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.643	0.357
T00-T07 Injuries involving multiple body regions	0.643	0.357
S10-S19 Injuries to the neck	0.643	0.357
E10.3 With ophthalmic complications	0.642	0.358
M25.75 Osteophyte (Pelvic region and thigh)	0.641	0.358
G50-G59 Nerve, nerve root and plexus disorders	0.641	0.359
I21.2 Acute transmural myocardial infarction of other sites	0.640	0.360
S80-S89 Injuries to the knee and lower leg	0.640	0.360
C16 Malignant neoplasm of stomach	0.640	0.360
T15-T19 Effects of foreign body entering through natural orifice	0.639	0.361
H92.1 Otorrhoea	0.638	0.362
J38.1 Polyp of vocal cord and larynx	0.638	0.362
J99 Respiratory disorders in diseases classified elsewhere	0.638	0.362
J96 Respiratory failure, not elsewhere classified	0.638	0.362
J95 Postprocedural respiratory disorders, not elsewhere classified	0.638	0.362
I35.8 Other aortic valve disorders	0.638	0.362
D21 Other benign neoplasms of connective and other soft tissue	0.637	0.363
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.636	0.364
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.636	0.364
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.636	0.364
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.636	0.364
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.636	0.364
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.636	0.364
E04 Other non-toxic goitre	0.635	0.364
J36 Peritonsillar abscess	0.635	0.365
M22.1 Recurrent subluxation of patella	0.634	0.366
M22.9 Disorder of patella, unspecified	0.634	0.366
M22.8 Other disorders of patella	0.634	0.366
M22.3 Other derangements of patella	0.634	0.366
M22.2 Patellofemoral disorders	0.634	0.366
M22.0 Recurrent dislocation of patella	0.634	0.366
E50-E64 Other nutritional deficiencies	0.634	0.366
R44 Other symptoms and signs involving general sensations and perceptions	0.634	0.366
D34 Benign neoplasm of thyroid gland	0.633	0.367
J33.8 Other polyp of sinus	0.633	0.367
T90 Sequelae of injuries of head	0.633	0.367
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.633	0.367
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.633	0.367
I22.9 Subsequent myocardial infarction of unspecified site	0.632	0.368
E27.4 Other and unspecified adrenocortical insufficiency	0.631	0.369
C90 Multiple myeloma and malignant plasma cell neoplasms	0.631	0.369
S90-S99 Injuries to the ankle and foot	0.631	0.369
Y85 Sequelae of transport accidents	0.631	0.369
J30.3 Other allergic rhinitis	0.630	0.370
J30.2 Other seasonal allergic rhinitis	0.630	0.370
J30.0 Vasomotor rhinitis	0.630	0.370
Y44.2 Anticoagulants	0.630	0.370
F31 Bipolar affective disorder	0.629	0.371
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.629	0.371
I86 Varicose veins of other sites	0.629	0.371
M19.8 Other specified arthrosis	0.628	0.371
M19.2 Other secondary arthrosis	0.628	0.371
M19.1 Posttraumatic arthrosis of other joints	0.628	0.371
D25.1 Intramural leiomyoma of uterus	0.628	0.372
H57 Other disorders of eye and adnexa	0.627	0.373
F25 Schizoaffective disorders	0.627	0.373
F23 Acute and transient psychotic disorders	0.627	0.373
F28 Other nonorganic psychotic disorders	0.627	0.373
F24 Induced delusional disorder	0.627	0.373
F21 Schizotypal disorder	0.627	0.373
H18 Other disorders of cornea	0.627	0.373
H52 Disorders of refraction and accommodation	0.627	0.373
Chapter XII Diseases of the skin and subcutaneous tissue	0.627	0.373
Y57.5 X-ray contrast media	0.626	0.374
M80 Osteoporosis with pathological fracture	0.625	0.375
J44 Other chronic obstructive pulmonary disease	0.625	0.375
E11.4 With neurological complications	0.624	0.376
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.624	0.376
T93 Sequelae of injuries of lower limb	0.622	0.378
G95 Other diseases of spinal cord	0.622	0.378

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations