TreeWAS – Variant ID: rs74452899

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XI Diseases of the digestive system	1.000	0.000
# Top node	1.000	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
K70-K77 Diseases of liver	0.998	0.002
K80 Cholelithiasis	0.997	0.003
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.996	0.004
K80.2 Calculus of gallbladder without cholecystitis	0.996	0.004
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.995	0.005
Chapter II Neoplasms	0.993	0.007
Chapter X Diseases of the respiratory system	0.992	0.008
K76 Other diseases of liver	0.991	0.009
C15-C26 Malignant neoplasms of digestive organs	0.991	0.009
R50-R69 General symptoms and signs	0.989	0.011
K86 Other diseases of pancreas	0.982	0.018
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.979	0.021
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.978	0.022
R53 Malaise and fatigue	0.976	0.024
S80-S89 Injuries to the knee and lower leg	0.974	0.026
R63 Symptoms and signs concerning food and fluid intake	0.972	0.028
D37-D48 Neoplasms of uncertain or unknown behaviour	0.969	0.031
K76.0 Fatty (change of) liver, not elsewhere classified	0.968	0.032
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.968	0.032
J90-J94 Other diseases of pleura	0.968	0.032
M15-M19 Arthrosis	0.965	0.035
J40-J47 Chronic lower respiratory diseases	0.962	0.038
Chapter V Mental and behavioural disorders	0.959	0.041
J44 Other chronic obstructive pulmonary disease	0.957	0.043
M17 Gonarthrosis [arthrosis of knee]	0.957	0.043
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.957	0.043
R41 Other symptoms and signs involving cognitive functions and awareness	0.956	0.044
J44.9 Chronic obstructive pulmonary disease, unspecified	0.954	0.046
D70-D77 Other diseases of blood and blood-forming organs	0.950	0.050
R63.4 Abnormal weight loss	0.940	0.060
C18 Malignant neoplasm of colon	0.939	0.061
M17.0 Primary gonarthrosis, bilateral	0.936	0.064
K83 Other diseases of biliary tract	0.934	0.066
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.926	0.074
K76.6 Portal hypertension	0.925	0.075
C20 Malignant neoplasm of rectum	0.925	0.075
K86.1 Other chronic pancreatitis	0.920	0.080
R50 Fever of unknown origin	0.915	0.085
R41.0 Disorientation, unspecified	0.913	0.087
K81 Cholecystitis	0.911	0.089
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.911	0.089
T36-T50 Poisoning by drugs, medicaments and biological substances	0.904	0.096
K86.8 Other specified diseases of pancreas	0.902	0.098
T88 Other complications of surgical and medical care, not elsewhere classified	0.902	0.098
J92 Pleural plaque	0.896	0.104
K83.0 Cholangitis	0.895	0.105
D70 Agranulocytosis	0.888	0.112
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.880	0.120
F00-F09 Organic, including symptomatic, mental disorders	0.875	0.125
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.875	0.125
J93 Pneumothorax	0.872	0.128
T81 Complications of procedures, not elsewhere classified	0.872	0.128
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.870	0.130
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.869	0.131
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.862	0.138
K85 Acute pancreatitis	0.859	0.141
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.858	0.142
K65-K67 Diseases of peritoneum	0.855	0.145
D75 Other diseases of blood and blood-forming organs	0.852	0.148
K81.1 Chronic cholecystitis	0.851	0.149
K76.9 Liver disease, unspecified	0.851	0.149
S82 Fracture of lower leg, including ankle	0.851	0.149
K74 Fibrosis and cirrhosis of liver	0.850	0.150
T88.7 Unspecified adverse effect of drug or medicament	0.850	0.150
M17.9 Gonarthrosis, unspecified	0.846	0.154
D80-D89 Certain disorders involving the immune mechanism	0.842	0.158
M80-M85 Disorders of bone density and structure	0.839	0.161
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.837	0.163
M20-M25 Other joint disorders	0.834	0.166
C16 Malignant neoplasm of stomach	0.833	0.167
J92.9 Pleural plaque without asbestos	0.831	0.169
R44 Other symptoms and signs involving general sensations and perceptions	0.831	0.169
K55-K64 Other diseases of intestines	0.830	0.170
R63.0 Anorexia	0.828	0.172
C18.0 Caecum	0.824	0.176
T66-T78 Other and unspecified effects of external causes	0.823	0.177
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.821	0.179
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.818	0.182
M19 Other arthrosis	0.818	0.182
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.818	0.182
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.817	0.183
R40 Somnolence, stupor and coma	0.817	0.183
R50.9 Fever, unspecified	0.816	0.184
K07 Dentofacial anomalies [including malocclusion]	0.816	0.184
Chapter I Certain infectious and parasitic diseases	0.812	0.188
K14 Diseases of tongue	0.811	0.189
S90-S99 Injuries to the ankle and foot	0.811	0.189
K04 Diseases of pulp and periapical tissues	0.811	0.189
D48.1 Connective and other soft tissue	0.807	0.193
S86 Injury of muscle and tendon at lower leg level	0.807	0.193
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.806	0.194
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.802	0.198
R10.4 Other and unspecified abdominal pain	0.802	0.198
C18.2 Ascending colon	0.802	0.198
R10 Abdominal and pelvic pain	0.802	0.198
S80 Superficial injury of lower leg	0.801	0.198
K73 Chronic hepatitis, not elsewhere classified	0.800	0.200
K70 Alcoholic liver disease	0.799	0.201
C19 Malignant neoplasm of rectosigmoid junction	0.798	0.202
C18.1 Appendix	0.796	0.204
D00-D09 In situ neoplasms	0.794	0.206
R46 Symptoms and signs involving appearance and behaviour	0.794	0.206
J93.9 Pneumothorax, unspecified	0.794	0.206
T86 Failure and rejection of transplanted organs and tissues	0.794	0.206
C26 Malignant neoplasm of other and ill-defined digestive organs	0.793	0.207
F60-F69 Disorders of adult personality and behaviour	0.792	0.208
T84.1 Mechanical complication of internal fixation device of bones of limb	0.791	0.209
M17.3 Other posttraumatic gonarthrosis	0.791	0.209
D45 Polycythaemia vera	0.790	0.210
C15 Malignant neoplasm of oesophagus	0.789	0.210
R57 Shock, not elsewhere classified	0.789	0.211
R19 Other symptoms and signs involving the digestive system and abdomen	0.787	0.213
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.786	0.214
K63 Other diseases of intestine	0.786	0.214
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.784	0.216
J95-J99 Other diseases of the respiratory system	0.782	0.218
M23 Internal derangement of knee	0.779	0.221
F03 Unspecified dementia	0.778	0.222
C17 Malignant neoplasm of small intestine	0.778	0.222
R50.0 Fever with chills	0.775	0.225
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.772	0.228
D75.1 Secondary polycythaemia	0.772	0.228
K35-K38 Diseases of appendix	0.771	0.229
R19.0 Intra-abdominal and pelvic swelling, mass and lump	0.770	0.230
T82.3 Mechanical complication of other vascular grafts	0.769	0.231
S81 Open wound of lower leg	0.767	0.233
R60 Oedema, not elsewhere classified	0.767	0.233
M91-M94 Chondropathies	0.766	0.234
K14.8 Other diseases of tongue	0.765	0.235
D47.2 Monoclonal gammopathy	0.765	0.235
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.764	0.236
C18.5 Splenic flexure	0.763	0.237
K12 Stomatitis and related lesions	0.762	0.238
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.762	0.238
K81.9 Cholecystitis, unspecified	0.761	0.239
R63.8 Other symptoms and signs concerning food and fluid intake	0.760	0.240
K57 Diverticular disease of intestine	0.758	0.242
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.758	0.242
K75 Other inflammatory liver diseases	0.757	0.243
F20 Schizophrenia	0.754	0.246
J91 Pleural effusion in conditions classified elsewhere	0.754	0.246
R54 Senility	0.753	0.247
K86.9 Disease of pancreas, unspecified	0.752	0.248
K86.0 Alcohol-induced chronic pancreatitis	0.750	0.250
R68 Other general symptoms and signs	0.750	0.250
K11 Diseases of salivary glands	0.750	0.250
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.748	0.252
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.746	0.254
M40-M43 Deforming dorsopathies	0.746	0.254
F10 Mental and behavioural disorders due to use of alcohol	0.744	0.256
R61 Hyperhidrosis	0.742	0.257
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.742	0.258
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.742	0.258
M23.3 Other meniscus derangements	0.741	0.259
C50-C50 Malignant neoplasm of breast	0.740	0.260
M86-M90 Other osteopathies	0.740	0.260
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.738	0.262
M65-M68 Disorders of synovium and tendon	0.738	0.262
K63.1 Perforation of intestine (nontraumatic)	0.738	0.262
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.738	0.262
M19.9 Arthrosis, unspecified	0.736	0.264
Chapter XX External causes of morbidity and mortality	0.736	0.264
K05 Gingivitis and periodontal diseases	0.735	0.265
K00 Disorders of tooth development and eruption	0.734	0.266
D73 Diseases of spleen	0.733	0.267
J94 Other pleural conditions	0.733	0.267
K74.3 Primary biliary cirrhosis	0.732	0.268
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.731	0.269
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.731	0.269
J80-J84 Other respiratory diseases principally affecting the interstitium	0.730	0.270
S82.6 Fracture of lateral malleolus	0.730	0.270
M60-M63 Disorders of muscles	0.730	0.270
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.729	0.271
K40-K46 Hernia	0.728	0.272
F00 Dementia in Alzheimer's disease	0.726	0.274
J60-J70 Lung diseases due to external agents	0.726	0.274
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.725	0.275
K85.9 Acute pancreatitis, unspecified	0.725	0.275
K83.8 Other specified diseases of biliary tract	0.725	0.275
K58 Irritable bowel syndrome	0.725	0.275
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.725	0.275
K07.3 Anomalies of tooth position	0.724	0.276
M84 Disorders of continuity of bone	0.723	0.277
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess	0.723	0.277
J09-J18 Influenza and pneumonia	0.721	0.279
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.721	0.279
M24 Other specific joint derangements	0.721	0.279
J47 Bronchiectasis	0.718	0.282
R26 Abnormalities of gait and mobility	0.718	0.282
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
S10-S19 Injuries to the neck	0.717	0.283
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.716	0.284
S82.8 Fractures of other parts of lower leg	0.715	0.285
K77 Liver disorders in diseases classified elsewhere	0.715	0.285
K71 Toxic liver disease	0.715	0.285
D86 Sarcoidosis	0.715	0.285
K80.3 Calculus of bile duct with cholangitis	0.715	0.285
K80.8 Other cholelithiasis	0.715	0.285
R95-R99 Ill-defined and unknown causes of mortality	0.714	0.286
S89 Other and unspecified injuries of lower leg	0.714	0.286
T87 Complications peculiar to reattachment and amputation	0.713	0.286
T80 Complications following infusion, transfusion and therapeutic injection	0.713	0.286
S40-S49 Injuries to the shoulder and upper arm	0.713	0.287
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.712	0.288
C40-C41 Malignant neoplasms of bone and articular cartilage	0.712	0.288
K86.3 Pseudocyst of pancreas	0.712	0.288
K76.7 Hepatorenal syndrome	0.711	0.289
K76.5 Hepatic veno-occlusive disease	0.711	0.289
K76.4 Peliosis hepatis	0.711	0.289
K76.3 Infarction of liver	0.711	0.289
K76.2 Central haemorrhagic necrosis of liver	0.711	0.289
K76.1 Chronic passive congestion of liver	0.711	0.289
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.710	0.290
C21 Malignant neoplasm of anus and anal canal	0.710	0.290
C23 Malignant neoplasm of gallbladder	0.710	0.290
K63.5 Polyp of colon	0.710	0.290
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.710	0.290
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.709	0.291
R62 Lack of expected normal physiological development	0.709	0.291
R64 Cachexia	0.709	0.291
R58 Haemorrhage, not elsewhere classified	0.709	0.291
T79-T79 Certain early complications of trauma	0.709	0.291
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.708	0.292
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.708	0.292
S83.2 Tear of meniscus, current	0.707	0.293
F22 Persistent delusional disorders	0.707	0.293
R40.2 Coma, unspecified	0.705	0.295
K90-K93 Other diseases of the digestive system	0.704	0.296
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.703	0.297
M00-M03 Infectious arthropathies	0.702	0.298
K56 Paralytic ileus and intestinal obstruction without hernia	0.702	0.298
T15-T19 Effects of foreign body entering through natural orifice	0.701	0.298
R43 Disturbances of smell and taste	0.701	0.299
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.701	0.299
K66 Other disorders of peritoneum	0.700	0.300
R47-R49 Symptoms and signs involving speech and voice	0.700	0.300
D72 Other disorders of white blood cells	0.700	0.300
Chapter VIII Diseases of the ear and mastoid process	0.699	0.301
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.699	0.301
S88 Traumatic amputation of lower leg	0.698	0.302
S87 Crushing injury of lower leg	0.698	0.302
S85 Injury of blood vessels at lower leg level	0.698	0.302
S84 Injury of nerves at lower leg level	0.698	0.302
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.698	0.302
J92.0 Pleural plaque with presence of asbestos	0.697	0.303
R63.6 Insufficient intake of food and water due to self neglect	0.697	0.303
R63.5 Abnormal weight gain	0.697	0.303
R63.3 Feeding difficulties and mismanagement	0.697	0.303
R63.2 Polyphagia	0.697	0.303
R63.1 Polydipsia	0.697	0.303
K80.1 Calculus of gallbladder with other cholecystitis	0.696	0.304
Chapter XII Diseases of the skin and subcutaneous tissue	0.696	0.304
T78 Adverse effects, not elsewhere classified	0.696	0.304
F10.0 Acute intoxication	0.696	0.304
T81.8 Other complications of procedures, not elsewhere classified	0.696	0.304
C16.9 Stomach, unspecified	0.695	0.305
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.695	0.305
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.695	0.305
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.695	0.305
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.695	0.305
Chapter VI Diseases of the nervous system	0.694	0.306
D55-D59 Haemolytic anaemias	0.694	0.306
M15 Polyarthrosis	0.692	0.308
K80.4 Calculus of bile duct with cholecystitis	0.691	0.309
K65 Peritonitis	0.691	0.309
J41 Simple and mucopurulent chronic bronchitis	0.690	0.310
J42 Unspecified chronic bronchitis	0.690	0.310
F01 Vascular dementia	0.688	0.312
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.688	0.312
F80-F89 Disorders of psychological development	0.688	0.312
F70-F79 Mental retardation	0.688	0.312
K09 Cysts of oral region, not elsewhere classified	0.688	0.312
S86.8 Injury of other muscles and tendons at lower leg level	0.688	0.312
T84.2 Mechanical complication of internal fixation device of other bones	0.688	0.312
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.687	0.313
T81.3 Disruption of operation wound, not elsewhere classified	0.687	0.313
K72 Hepatic failure, not elsewhere classified	0.687	0.313
S82.3 Fracture of lower end of tibia	0.686	0.314
M17.5 Other secondary gonarthrosis	0.686	0.314
M17.4 Other secondary gonarthrosis, bilateral	0.686	0.314
M17.2 Posttraumatic gonarthrosis, bilateral	0.686	0.314
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.686	0.314
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.686	0.314
T82.4 Mechanical complication of vascular dialysis catheter	0.686	0.314
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.686	0.314
T82.0 Mechanical complication of heart valve prosthesis	0.686	0.314
R41.2 Retrograde amnesia	0.686	0.314
R41.1 Anterograde amnesia	0.686	0.314
K04.8 Radicular cyst	0.686	0.314
T43.3 Phenothiazine antipsychotics and neuroleptics	0.684	0.316
R45 Symptoms and signs involving emotional state	0.684	0.316
K86.2 Cyst of pancreas	0.683	0.317
J90 Pleural effusion, not elsewhere classified	0.682	0.318
D74 Methaemoglobinaemia	0.681	0.319
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.681	0.319
D71 Functional disorders of polymorphonuclear neutrophils	0.681	0.319
C60-C63 Malignant neoplasms of male genital organs	0.681	0.319
J46 Status asthmaticus	0.681	0.319
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.679	0.321
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.679	0.321
M19.93 Arthrosis, unspecified (Forearm)	0.678	0.322
K85.1 Biliary acute pancreatitis	0.677	0.323
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.677	0.323
R59 Enlarged lymph nodes	0.677	0.323
K57.1 Diverticular disease of small intestine without perforation or abscess	0.677	0.323
F99-F99 Unspecified mental disorder	0.677	0.323
S20-S29 Injuries to the thorax	0.677	0.323
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.676	0.324
C18.9 Colon, unspecified	0.676	0.324
S92 Fracture of foot, except ankle	0.675	0.325
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.675	0.325
A00-A09 Intestinal infectious diseases	0.675	0.325
K82 Other diseases of gallbladder	0.674	0.326
C18.8 Overlapping lesion of colon	0.673	0.327
C18.6 Descending colon	0.673	0.327
C18.3 Hepatic flexure	0.673	0.327
F60 Specific personality disorders	0.673	0.327
J20-J22 Other acute lower respiratory infections	0.672	0.328
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.672	0.328
D03 Melanoma in situ	0.672	0.328
R29.6 Tendency to fall, not elsewhere classified	0.672	0.328
Chapter XXII Codes for special purposes	0.671	0.329
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.671	0.329
K83.9 Disease of biliary tract, unspecified	0.670	0.330
K83.5 Biliary cyst	0.670	0.330
K83.4 Spasm of sphincter of Oddi	0.670	0.330
K83.3 Fistula of bile duct	0.670	0.330
K83.2 Perforation of bile duct	0.670	0.330
R12 Heartburn	0.666	0.334
F20.0 Paranoid schizophrenia	0.666	0.334
C25 Malignant neoplasm of pancreas	0.665	0.335
K06 Other disorders of gingiva and edentulous alveolar ridge	0.664	0.336
K03 Other diseases of hard tissues of teeth	0.664	0.336
M17.1 Other primary gonarthrosis	0.663	0.337
R44.1 Visual hallucinations	0.663	0.337
R46.8 Other symptoms and signs involving appearance and behaviour	0.663	0.337
K12.2 Cellulitis and abscess of mouth	0.662	0.337
R44.3 Hallucinations, unspecified	0.662	0.338
D46 Myelodysplastic syndromes	0.659	0.341
K73.9 Chronic hepatitis, unspecified	0.658	0.342
K58.9 Irritable bowel syndrome without diarrhoea	0.657	0.343
R21 Rash and other nonspecific skin eruption	0.657	0.343
Q80-Q89 Other congenital malformations	0.656	0.344
J93.1 Other spontaneous pneumothorax	0.656	0.344
R50.8 Other specified fever	0.656	0.344
R50.2 Drug-induced fever	0.656	0.344
R50.1 Persistent fever	0.656	0.344
D43.2 Brain, unspecified	0.656	0.344
F12 Mental and behavioural disorders due to use of cannabinoids	0.655	0.345
K81.8 Other cholecystitis	0.653	0.347
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.653	0.347
C18.4 Transverse colon	0.652	0.347
R19.5 Other fecal abnormalities	0.653	0.347
C64-C68 Malignant neoplasms of urinary tract	0.652	0.348
C26.0 Intestinal tract, part unspecified	0.652	0.348
T63 Toxic effect of contact with venomous animals	0.650	0.350
J44.8 Other specified chronic obstructive pulmonary disease	0.650	0.350
S50-S59 Injuries to the elbow and forearm	0.649	0.351
M80 Osteoporosis with pathological fracture	0.649	0.351
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.649	0.351
C51-C58 Malignant neoplasms of female genital organs	0.649	0.351
R60.0 Localised oedema	0.649	0.351
C15.9 Oesophagus, unspecified	0.649	0.351
M21 Other acquired deformities of limbs	0.648	0.352
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.648	0.352
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.648	0.352
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.648	0.352
T46 Poisoning by agents primarily affecting the cardiovascular system	0.648	0.352
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.648	0.352
T41 Poisoning by anaesthetics and therapeutic gases	0.648	0.352
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.648	0.352
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.648	0.352
T36 Poisoning by systemic antibiotics	0.648	0.352
T42.4 Benzodiazepines	0.648	0.352
T88.9 Complication of surgical and medical care, unspecified	0.647	0.353
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.647	0.353
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.647	0.353
T88.5 Other complications of anaesthesia	0.647	0.353
T88.3 Malignant hyperthermia due to anaesthesis	0.647	0.353
T88.2 Shock due to anaesthesia	0.647	0.353
T88.1 Other complications following immunisation, not elsewhere classified	0.647	0.353
T88.0 Infection following immunisation	0.647	0.353
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.646	0.353
R25 Abnormal involuntary movements	0.646	0.354
K74.0 Hepatic fibrosis	0.645	0.354
R57.0 Cardiogenic shock	0.645	0.355
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.645	0.355
K70.1 Alcoholic hepatitis	0.644	0.355
B35-B49 Mycoses	0.644	0.356
K56.7 Ileus, unspecified	0.644	0.356
D47.3 Essential (haemorrhagic) thrombocythaemia	0.643	0.357
T82.1 Mechanical complication of cardiac electronic device	0.643	0.357
S82.60 Fracture of lateral malleolus (closed)	0.643	0.357
D75.9 Disease of blood and blood-forming organs, unspecified	0.642	0.358
D04 Carcinoma in situ of skin	0.641	0.359
J40 Bronchitis, not specified as acute or chronic	0.639	0.361
C16.0 Cardia	0.639	0.361
B95-B98 Bacterial, viral and other infectious agents	0.639	0.361
M19.97 Arthrosis, unspecified (Ankle and foot)	0.639	0.361
T51 Toxic effect of alcohol	0.638	0.362
R10.0 Acute abdomen	0.637	0.363
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.637	0.363
S30 Superficial injury of abdomen, lower back and pelvis	0.635	0.365
T86.0 Bone-marrow transplant rejection	0.635	0.365
J98 Other respiratory disorders	0.635	0.365
M50-M54 Other dorsopathies	0.634	0.366
K04.9 Other and unspecified diseases of pulp and periapical tissues	0.633	0.367
M18 Arthrosis of first carpometacarpal joint	0.632	0.368
K40 Inguinal hernia	0.631	0.369
S82.0 Fracture of patella	0.628	0.372
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.628	0.372
F02 Dementia in other diseases classified elsewhere	0.628	0.372
F09 Unspecified organic or symptomatic mental disorder	0.628	0.372
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.628	0.372
G90-G99 Other disorders of the nervous system	0.628	0.372
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.627	0.373
D48.7 Other specified sites	0.627	0.373
D48.6 Breast	0.627	0.373
D48.5 Skin	0.627	0.373
D48.4 Peritoneum	0.627	0.373
D48.3 Retroperitoneum	0.627	0.373
D48.2 Peripheral nerves and autonomic nervous system	0.627	0.373
D48.0 Bone and articular cartilage	0.627	0.373
C17.0 Duodenum	0.625	0.374
J93.8 Other pneumothorax	0.625	0.375
J93.0 Spontaneous tension pneumothorax	0.625	0.375
R44.0 Auditory hallucinations	0.625	0.375
T81.9 Unspecified complication of procedure	0.625	0.375
T81.7 Vascular complications following a procedure, not elsewhere classified	0.625	0.375
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.625	0.375
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.625	0.375
D47.1 Chronic myeloproliferative disease	0.624	0.375
M84.1 Nonunion of fracture [pseudarthrosis]	0.624	0.376
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.623	0.377
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.623	0.377
T84.3 Mechanical complication of other bone devices, implants and grafts	0.623	0.377
T84.0 Mechanical complication of internal joint prosthesis	0.623	0.377
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.622	0.378
K11.5 Sialolithiasis	0.622	0.378
K04.7 Periapical abscess without sinus	0.620	0.380
F00.9 Dementia in Alzheimer's disease, unspecified	0.619	0.381
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.619	0.381
S82.80 Fractures of other parts of lower leg (closed)	0.618	0.382
F25 Schizoaffective disorders	0.618	0.382
F23 Acute and transient psychotic disorders	0.618	0.382
F28 Other nonorganic psychotic disorders	0.618	0.382
F24 Induced delusional disorder	0.618	0.382
F21 Schizotypal disorder	0.618	0.382
K07.6 Temporomandibular joint disorders	0.617	0.383
K85.8 Other acute pancreatitis	0.616	0.384
K85.3 Drug-induced acute pancreatitis	0.616	0.384
K85.2 Alcohol-induced acute pancreatitis	0.616	0.384
K85.0 Idiopathic acute pancreatitis	0.616	0.384
K42 Umbilical hernia	0.616	0.384
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.616	0.384
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.615	0.385
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.615	0.385
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.615	0.385
D47.4 Osteomyelofibrosis	0.615	0.385
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.615	0.385
S80.8 Other superficial injuries of lower leg	0.615	0.385
S80.0 Contusion of knee	0.615	0.385
R41.3 Other amnesia	0.614	0.386
M94 Other disorders of cartilage	0.613	0.387
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.613	0.387
J15 Bacterial pneumonia, not elsewhere classified	0.613	0.387
K67 Disorders of peritoneum in infectious diseases classified elsewhere	0.613	0.387
K02 Dental caries	0.612	0.388
C62 Malignant neoplasm of testis	0.612	0.388
M81 Osteoporosis without pathological fracture	0.612	0.388
A04 Other bacterial intestinal infections	0.611	0.389
K10 Other diseases of jaws	0.611	0.389
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.611	0.389
F29 Unspecified nonorganic psychosis	0.611	0.389
D75.8 Other specified diseases of blood and blood-forming organs	0.611	0.389
D75.2 Essential thrombocytosis	0.611	0.389
D75.0 Familial erythrocytosis	0.611	0.389
S82.2 Fracture of shaft of tibia	0.610	0.390
S82.9 Fracture of lower leg, part unspecified	0.610	0.390
S82.7 Multiple fractures of lower leg	0.610	0.390
K74.5 Biliary cirrhosis, unspecified	0.609	0.391
K74.4 Secondary biliary cirrhosis	0.609	0.391
K74.2 Hepatic fibrosis with hepatic sclerosis	0.609	0.391
K74.1 Hepatic sclerosis	0.609	0.391
M24.1 Other articular cartilage disorders	0.609	0.391
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.609	0.391
M19.98 Arthrosis, unspecified (Other)	0.608	0.392
K70.0 Alcoholic fatty liver	0.607	0.393
T78.4 Allergy, unspecified	0.607	0.393
K36 Other appendicitis	0.607	0.393
G50-G59 Nerve, nerve root and plexus disorders	0.606	0.394

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations