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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74456537
log Bayes Factor = 16.3397
Chromosome 2   position 158,865,364  (GRCh37) Explore rs74456537 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.999 0.001 0.000
Chapter XIV Diseases of the genitourinary system
0.996 0.004 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.994 0.006 0.000
N17-N19 Renal failure
0.993 0.007 0.000
Chapter VI Diseases of the nervous system
0.991 0.009 0.000
Chapter II Neoplasms
0.990 0.010 0.000
Chapter X Diseases of the respiratory system
0.984 0.016 0.000
Chapter XX External causes of morbidity and mortality
0.983 0.017 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.982 0.018 0.000
A30-A49 Other bacterial diseases
0.980 0.020 0.000
R30-R39 Symptoms and signs involving the urinary system
0.980 0.020 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.979 0.021 0.000
N17 Acute renal failure
0.975 0.025 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.975 0.025 0.000
G40-G47 Episodic and paroxysmal disorders
0.970 0.030 0.000
B07 Viral warts
0.967 0.033 0.000
R35 Polyuria
0.967 0.033 0.000
N20-N23 Urolithiasis
0.963 0.037 0.000
Chapter IX Diseases of the circulatory system
0.963 0.037 0.000
N17.9 Acute renal failure, unspecified
0.963 0.037 0.000
S60-S69 Injuries to the wrist and hand
0.962 0.038 0.000
A41 Other septicaemia
0.962 0.038 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.956 0.044 0.000
G47 Sleep disorders
0.953 0.047 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.951 0.049 0.000
B95-B98 Bacterial, viral and other infectious agents
0.949 0.051 0.000
I95 Hypotension
0.949 0.051 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.947 0.053 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.946 0.054 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.942 0.058 0.000
J09-J18 Influenza and pneumonia
0.942 0.058 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.940 0.060 0.000
C79 Secondary malignant neoplasm of other sites
0.940 0.060 0.000
N20 Calculus of kidney and ureter
0.937 0.063 0.000
I95.9 Hypotension, unspecified
0.935 0.065 0.000
A41.9 Septicaemia, unspecified
0.935 0.065 0.000
E70-E90 Metabolic disorders
0.934 0.066 0.000
Chapter VII Diseases of the eye and adnexa
0.933 0.067 0.000
G47.3 Sleep apnoea
0.930 0.070 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.930 0.070 0.000
N10-N16 Renal tubulo-interstitial diseases
0.921 0.079 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.921 0.079 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.921 0.079 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.920 0.080 0.000
Chapter V Mental and behavioural disorders
0.919 0.081 0.000
N19 Unspecified renal failure
0.912 0.088 0.000
J18 Pneumonia, organism unspecified
0.911 0.089 0.000
W00-W19 Falls
0.906 0.094 0.000
S68 Traumatic amputation of wrist and hand
0.903 0.097 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.900 0.100 0.000
E87.5 Hyperkalaemia
0.895 0.105 0.000
R47-R49 Symptoms and signs involving speech and voice
0.893 0.107 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.892 0.108 0.000
N20.1 Calculus of ureter
0.891 0.109 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.890 0.110 0.000
I05-I09 Chronic rheumatic heart diseases
0.890 0.110 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.888 0.112 0.000
J60-J70 Lung diseases due to external agents
0.885 0.115 0.000
N13 Obstructive and reflux uropathy
0.883 0.117 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.882 0.118 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.879 0.121 0.000
J95-J99 Other diseases of the respiratory system
0.875 0.125 0.000
B35-B49 Mycoses
0.872 0.128 0.000
N20.2 Calculus of kidney with calculus of ureter
0.869 0.131 0.000
N18 Chronic renal failure
0.867 0.133 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.867 0.133 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.866 0.134 0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)
0.861 0.139 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.858 0.142 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.856 0.144 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.856 0.144 0.000
G30-G32 Other degenerative diseases of the nervous system
0.856 0.144 0.000
R27 Other lack of coordination
0.856 0.144 0.000
I30-I52 Other forms of heart disease
0.855 0.145 0.000
R39 Other symptoms and signs involving the urinary system
0.851 0.149 0.000
G20-G26 Extrapyramidal and movement disorders
0.851 0.149 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.850 0.150 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.849 0.151 0.000
C78.0 Secondary malignant neoplasm of lung
0.846 0.154 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.845 0.155 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.845 0.155 0.000
C78.7 Secondary malignant neoplasm of liver
0.844 0.156 0.000
R29.6 Tendency to fall, not elsewhere classified
0.843 0.157 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.840 0.160 0.000
J18.9 Pneumonia, unspecified
0.837 0.163 0.000
N21 Calculus of lower urinary tract
0.837 0.163 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.836 0.164 0.000
J18.1 Lobar pneumonia, unspecified
0.834 0.166 0.000
J20-J22 Other acute lower respiratory infections
0.831 0.169 0.000
N13.3 Other and unspecified hydronephrosis
0.829 0.171 0.000
S00-S09 Injuries to the head
0.828 0.172 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.826 0.174 0.000
Chapter XXII Codes for special purposes
0.826 0.174 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.821 0.179 0.000
Chapter VIII Diseases of the ear and mastoid process
0.819 0.181 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.817 0.183 0.000
N75 Diseases of Bartholin's gland
0.816 0.184 0.000
J90-J94 Other diseases of pleura
0.816 0.184 0.000
E86 Volume depletion
0.815 0.185 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.815 0.185 0.000
G47.9 Sleep disorder, unspecified
0.813 0.187 0.000
Y52 Agents primarily affecting the cardiovascular system
0.812 0.188 0.000
S40-S49 Injuries to the shoulder and upper arm
0.810 0.190 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.802 0.198 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.801 0.199 0.000
C34 Malignant neoplasm of bronchus and lung
0.800 0.200 0.000
S90-S99 Injuries to the ankle and foot
0.796 0.204 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.795 0.205 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.793 0.207 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.792 0.208 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.792 0.208 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.789 0.211 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.789 0.211 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.788 0.212 0.000
T82.3 Mechanical complication of other vascular grafts
0.787 0.213 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.787 0.213 0.000
J69 Pneumonitis due to solids and liquids
0.787 0.213 0.000
N73 Other female pelvic inflammatory diseases
0.786 0.214 0.000
E65-E68 Obesity and other hyperalimentation
0.785 0.215 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.783 0.217 0.000
T86 Failure and rejection of transplanted organs and tissues
0.782 0.217 0.000
I50 Heart failure
0.782 0.218 0.000
I95.1 Orthostatic hypotension
0.782 0.218 0.000
W19 Unspecified fall
0.782 0.218 0.000
I95.2 Hypotension due to drugs
0.782 0.218 0.000
E83 Disorders of mineral metabolism
0.782 0.218 0.000
Y43 Primarily systemic agents
0.781 0.219 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.780 0.219 0.000
B37 Candidiasis
0.780 0.220 0.000
Q60-Q64 Congenital malformations of the urinary system
0.780 0.220 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.779 0.221 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.779 0.221 0.000
C91 Lymphoid leukaemia
0.779 0.221 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.779 0.221 0.000
T82.1 Mechanical complication of cardiac electronic device
0.777 0.223 0.000
R27.0 Ataxia, unspecified
0.777 0.223 0.000
R42 Dizziness and giddiness
0.776 0.224 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.773 0.227 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.772 0.228 0.000
Chapter XXI Factors influencing health status and contact with health services
0.769 0.231 0.000
T87 Complications peculiar to reattachment and amputation
0.769 0.231 0.000
A49 Bacterial infection of unspecified site
0.769 0.231 0.000
G90-G99 Other disorders of the nervous system
0.768 0.232 0.000
A00-A09 Intestinal infectious diseases
0.768 0.232 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.768 0.232 0.000
E20-E35 Disorders of other endocrine glands
0.767 0.233 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.767 0.233 0.000
R47 Speech disturbances, not elsewhere classified
0.767 0.233 0.000
R32 Unspecified urinary incontinence
0.765 0.235 0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.765 0.235 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.765 0.235 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.764 0.236 0.000
G70-G73 Diseases of myoneural junction and muscle
0.762 0.238 0.000
H10-H13 Disorders of conjunctiva
0.762 0.238 0.000
I08 Multiple valve diseases
0.761 0.238 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.760 0.239 0.000
V40-V49 Car occupant injured in transport accident
0.760 0.240 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.759 0.241 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.759 0.241 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.759 0.241 0.000
Y40 Systemic antibiotics
0.758 0.242 0.000
K50-K52 Noninfective enteritis and colitis
0.757 0.243 0.000
Chapter XI Diseases of the digestive system
0.754 0.246 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.754 0.246 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.753 0.247 0.000
F03 Unspecified dementia
0.753 0.247 0.000
I05 Rheumatic mitral valve diseases
0.752 0.248 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.752 0.248 0.000
W07 Fall involving chair
0.752 0.248 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.751 0.249 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.751 0.249 0.000
E87.3 Alkalosis
0.750 0.249 0.000
R30 Pain associated with micturition
0.750 0.250 0.000
V20-V29 Motorcycle rider injured in transport accident
0.750 0.250 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.750 0.250 0.000
K51 Ulcerative colitis
0.747 0.253 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.747 0.253 0.000
N21.0 Calculus in bladder
0.747 0.253 0.000
S50-S59 Injuries to the elbow and forearm
0.746 0.254 0.000
S01 Open wound of head
0.746 0.254 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.744 0.256 0.000
R49 Voice disturbances
0.742 0.258 0.000
K51.9 Ulcerative colitis, unspecified
0.741 0.259 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.740 0.260 0.000
H25-H28 Disorders of lens
0.739 0.261 0.000
V80-V89 Other land transport accidents
0.738 0.261 0.000
B25-B34 Other viral diseases
0.738 0.262 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.736 0.264 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.735 0.265 0.000
S10-S19 Injuries to the neck
0.735 0.265 0.000
J00-J06 Acute upper respiratory infections
0.735 0.265 0.000
W20-W49 Exposure to inanimate mechanical forces
0.734 0.265 0.000
R45 Symptoms and signs involving emotional state
0.734 0.266 0.000
E87.7 Fluid overload
0.734 0.266 0.000
B02 Zoster [herpes zoster]
0.732 0.268 0.000
B37.0 Candidal stomatitis
0.732 0.268 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.729 0.270 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.729 0.271 0.000
S67 Crushing injury of wrist and hand
0.727 0.272 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.727 0.273 0.000
H40-H42 Glaucoma
0.727 0.273 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.727 0.273 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.726 0.274 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.726 0.274 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.726 0.274 0.000
I99 Other and unspecified disorders of circulatory system
0.725 0.274 0.000
B15-B19 Viral hepatitis
0.725 0.275 0.000
N18.0 End-stage renal disease
0.725 0.275 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.725 0.275 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.724 0.276 0.000
N75.0 Cyst of Bartholin's gland
0.724 0.276 0.000
C79.2 Secondary malignant neoplasm of skin
0.723 0.277 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.721 0.279 0.000
V10-V19 Pedal cyclist injured in transport accident
0.720 0.280 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.719 0.281 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
B99-B99 Other infectious diseases
0.717 0.283 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.717 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.717 0.283 0.000
B65-B83 Helminthiases
0.717 0.283 0.000
B50-B64 Protozoal diseases
0.717 0.283 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.717 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.717 0.283 0.000
A80-A89 Viral infections of the central nervous system
0.717 0.283 0.000
A75-A79 Rickettsioses
0.717 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.717 0.283 0.000
A65-A69 Other spirochaetal diseases
0.717 0.283 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.717 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.717 0.283 0.000
A15-A19 Tuberculosis
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.283 0.000
Y57 Other and unspecified drugs and medicaments
0.716 0.284 0.000
H30-H36 Disorders of choroid and retina
0.716 0.284 0.000
N20.9 Urinary calculus, unspecified
0.716 0.284 0.000
J69.0 Pneumonitis due to food and vomit
0.716 0.284 0.000
C78.2 Secondary malignant neoplasm of pleura
0.714 0.286 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.714 0.286 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.713 0.287 0.000
E87.0 Hyperosmolality and hypernatraemia
0.712 0.288 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.712 0.288 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.712 0.288 0.000
S80-S89 Injuries to the knee and lower leg
0.711 0.289 0.000
S20-S29 Injuries to the thorax
0.711 0.289 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.711 0.289 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.710 0.289 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.710 0.290 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.710 0.290 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.710 0.290 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.709 0.290 0.000
W06 Fall involving bed
0.708 0.292 0.000
J98 Other respiratory disorders
0.706 0.294 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.706 0.294 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.706 0.294 0.000
K50 Crohn's disease [regional enteritis]
0.706 0.294 0.000
C34.1 Upper lobe, bronchus or lung
0.705 0.295 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.704 0.295 0.000
Y35-Y36 Legal intervention and operations of war
0.704 0.295 0.000
Y10-Y34 Event of undetermined intent
0.704 0.295 0.000
Y00-Y09 Assault
0.704 0.295 0.000
X85-X99 Assault
0.704 0.295 0.000
X60-X84 Intentional self-harm
0.704 0.295 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.704 0.295 0.000
X50-X57 Overexertion, travel and privation
0.704 0.295 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.704 0.295 0.000
X30-X39 Exposure to forces of nature
0.704 0.295 0.000
X20-X29 Contact with venomous animals and plants
0.704 0.295 0.000
X10-X19 Contact with heat and hot substances
0.704 0.295 0.000
X00-X09 Exposure to smoke, fire and flames
0.704 0.295 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.704 0.295 0.000
W75-W84 Other accidental threats to breathing
0.704 0.295 0.000
W65-W74 Accidental drowning and submersion
0.704 0.295 0.000
W50-W64 Exposure to animate mechanical forces
0.704 0.295 0.000
V98-V99 Other and unspecified transport accidents
0.704 0.295 0.000
V95-V97 Air and space transport accidents
0.704 0.295 0.000
V90-V94 Water transport accidents
0.704 0.295 0.000
V70-V79 Bus occupant injured in transport accident
0.704 0.295 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.704 0.295 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.704 0.295 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.704 0.295 0.000
V01-V09 Pedestrian injured in transport accident
0.704 0.295 0.000
C92 Myeloid leukaemia
0.704 0.296 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.704 0.296 0.000
B06 Rubella [German measles]
0.704 0.296 0.000
B05 Measles
0.704 0.296 0.000
B01 Varicella [chickenpox]
0.704 0.296 0.000
B00 Herpesviral [herpes simplex] infections
0.704 0.296 0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions
0.704 0.296 0.000
B04 Monkeypox
0.704 0.296 0.000
B03 Smallpox
0.704 0.296 0.000
A48 Other bacterial diseases, not elsewhere classified
0.703 0.297 0.000
A44 Bartonellosis
0.703 0.297 0.000
A43 Nocardiosis
0.703 0.297 0.000
A42 Actinomycosis
0.703 0.297 0.000
A40 Streptococcal septicaemia
0.703 0.297 0.000
A39 Meningococcal infection
0.703 0.297 0.000
A37 Whooping cough
0.703 0.297 0.000
A36 Diphtheria
0.703 0.297 0.000
A32 Listeriosis
0.703 0.297 0.000
A31 Infection due to other mycobacteria
0.703 0.297 0.000
A30 Leprosy [Hansen's disease]
0.703 0.297 0.000
A46 Erysipelas
0.703 0.297 0.000
A38 Scarlet fever
0.703 0.297 0.000
A35 Other tetanus
0.703 0.297 0.000
A34 Obstetrical tetanus
0.703 0.297 0.000
A33 Tetanus neonatorum
0.703 0.297 0.000
N18.9 Chronic renal failure, unspecified
0.703 0.297 0.000
R36 Urethral discharge
0.702 0.298 0.000
R34 Anuria and oliguria
0.702 0.298 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.702 0.298 0.000
I07 Rheumatic tricuspid valve diseases
0.702 0.298 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.702 0.298 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.701 0.298 0.000
G44 Other headache syndromes
0.701 0.299 0.000
Q61 Cystic kidney disease
0.700 0.300 0.000
J11 Influenza, virus not identified
0.699 0.301 0.000
S02 Fracture of skull and facial bones
0.699 0.301 0.000
N17.8 Other acute renal failure
0.699 0.301 0.000
N17.2 Acute renal failure with medullary necrosis
0.699 0.301 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.699 0.301 0.000
N17.0 Acute renal failure with tubular necrosis
0.699 0.301 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.699 0.301 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.699 0.301 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.699 0.301 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.699 0.301 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.699 0.301 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.699 0.301 0.000
N11 Chronic tubulo-interstitial nephritis
0.698 0.302 0.000
N75.1 Abscess of Bartholin's gland
0.698 0.302 0.000
I50.0 Congestive heart failure
0.698 0.302 0.000
G20 Parkinson's disease
0.697 0.303 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.695 0.304 0.000
E87.2 Acidosis
0.696 0.304 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.695 0.305 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.695 0.305 0.000
G41 Status epilepticus
0.695 0.305 0.000
J20 Acute bronchitis
0.693 0.307 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.693 0.307 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.692 0.308 0.000
G24 Dystonia
0.692 0.308 0.000
T58 Toxic effect of carbon monoxide
0.692 0.308 0.000
S70-S79 Injuries to the hip and thigh
0.691 0.309 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.691 0.309 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.690 0.309 0.000
I00-I02 Acute rheumatic fever
0.690 0.310 0.000
F00 Dementia in Alzheimer's disease
0.690 0.310 0.000
H25 Senile cataract
0.690 0.310 0.000
S69 Other and unspecified injuries of wrist and hand
0.690 0.310 0.000
S65 Injury of blood vessels at wrist and hand level
0.690 0.310 0.000
S60 Superficial injury of wrist and hand
0.690 0.310 0.000
A41.8 Other specified septicaemia
0.689 0.310 0.000
A41.4 Septicaemia due to anaerobes
0.689 0.310 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.689 0.310 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.689 0.310 0.000
T79-T79 Certain early complications of trauma
0.688 0.312 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.687 0.313 0.000
Z60 Problems related to social environment
0.686 0.314 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.685 0.315 0.000
W19.3 Sports and athletics area
0.685 0.315 0.000
C85.1 B-cell lymphoma, unspecified
0.684 0.316 0.000
H55-H59 Other disorders of eye and adnexa
0.684 0.316 0.000
C34.9 Bronchus or lung, unspecified
0.684 0.316 0.000
F01 Vascular dementia
0.683 0.316 0.000
T17 Foreign body in respiratory tract
0.683 0.317 0.000
G47.8 Other sleep disorders
0.683 0.317 0.000
G47.4 Narcolepsy and cataplexy
0.683 0.317 0.000
G47.2 Disorders of the sleep-wake schedule
0.683 0.317 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.683 0.317 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.683 0.317 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.682 0.318 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.682 0.318 0.000
H90-H95 Other disorders of ear
0.681 0.319 0.000
N73.9 Female pelvic inflammatory disease, unspecified
0.681 0.319 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.680 0.320 0.000
R41.0 Disorientation, unspecified
0.680 0.320 0.000
I95.8 Other hypotension
0.680 0.320 0.000
I95.0 Idiopathic hypotension
0.680 0.320 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.680 0.320 0.000
S64 Injury of nerves at wrist and hand level
0.680 0.320 0.000
J93 Pneumothorax
0.680 0.320 0.000
G62 Other polyneuropathies
0.679 0.321 0.000
C32 Malignant neoplasm of larynx
0.679 0.321 0.000
J95.8 Other postprocedural respiratory disorders
0.679 0.321 0.000
E40-E46 Malnutrition
0.678 0.322 0.000
E83.5 Disorders of calcium metabolism
0.678 0.322 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.677 0.323 0.000
I31 Other diseases of pericardium
0.677 0.323 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.677 0.323 0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.676 0.324 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.676 0.324 0.000
J17 Pneumonia in diseases classified elsewhere
0.675 0.325 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.675 0.325 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.675 0.325 0.000
J12 Viral pneumonia, not elsewhere classified
0.675 0.325 0.000
J10 Influenza due to identified influenza virus
0.675 0.325 0.000
J14 Pneumonia due to Haemophilus influenzae
0.675 0.325 0.000
J09 Influenza due to certain identified influenza virus
0.675 0.325 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.674 0.325 0.000
R46 Symptoms and signs involving appearance and behaviour
0.674 0.326 0.000
R43 Disturbances of smell and taste
0.674 0.326 0.000
C79.6 Secondary malignant neoplasm of ovary
0.674 0.326 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.674 0.326 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.674 0.326 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.674 0.326 0.000
E88 Other metabolic disorders
0.673 0.326 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.672 0.328 0.000
R25 Abnormal involuntary movements
0.671 0.329 0.000
I46 Cardiac arrest
0.671 0.329 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.671 0.329 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.671 0.329 0.000
C91.1 Chronic lymphocytic leukaemia
0.671 0.329 0.000
E66 Obesity
0.670 0.329 0.000
R40 Somnolence, stupor and coma
0.670 0.330 0.000
E85 Amyloidosis
0.669 0.331 0.000
E84 Cystic fibrosis
0.669 0.331 0.000
E79 Disorders of purine and pyrimidine metabolism
0.669 0.331 0.000
E77 Disorders of glycoprotein metabolism
0.669 0.331 0.000
E76 Disorders of glycosaminoglycan metabolism
0.669 0.331 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.669 0.331 0.000
E74 Other disorders of carbohydrate metabolism
0.669 0.331 0.000
E73 Lactose intolerance
0.669 0.331 0.000
E72 Other disorders of amino-acid metabolism
0.669 0.331 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.669 0.331 0.000
E70 Disorders of aromatic amino-acid metabolism
0.669 0.331 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.669 0.331 0.000
N00-N08 Glomerular diseases
0.669 0.331 0.000
K40-K46 Hernia
0.668 0.331 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.668 0.332 0.000
T66-T78 Other and unspecified effects of external causes
0.667 0.333 0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
0.667 0.333 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.666 0.333 0.000
C95 Leukaemia of unspecified cell type
0.666 0.333 0.000
C94 Other leukaemias of specified cell type
0.666 0.333 0.000
C93 Monocytic leukaemia
0.666 0.333 0.000
C88 Malignant immunoproliferative diseases
0.666 0.333 0.000
C86 Other specified types of T/NK-cell lymphoma
0.666 0.333 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.666 0.333 0.000
C81 Hodgkin's disease
0.666 0.333 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.665 0.335 0.000
I38 Endocarditis, valve unspecified
0.664 0.336 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.663 0.336 0.000
S40 Superficial injury of shoulder and upper arm
0.662 0.337 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.662 0.338 0.000
Y43.3 Other antineoplastic drugs
0.661 0.339 0.000
F60-F69 Disorders of adult personality and behaviour
0.661 0.339 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.661 0.339 0.000
N15 Other renal tubulo-interstitial diseases
0.661 0.339 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.661 0.339 0.000
N10 Acute tubulo-interstitial nephritis
0.661 0.339 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.660 0.339 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.660 0.339 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.660 0.339 0.000
G30 Alzheimer's disease
0.660 0.340 0.000
Y59 Other and unspecified vaccines and biological substances
0.660 0.340 0.000
Y58 Bacterial vaccines
0.660 0.340 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.660 0.340 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.660 0.340 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.660 0.340 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.660 0.340 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.660 0.340 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.660 0.340 0.000
Y48 Anaesthetics and therapeutic gases
0.660 0.340 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.660 0.340 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.660 0.340 0.000
Y44 Agents primarily affecting blood constituents
0.660 0.340 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.660 0.340 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.660 0.340 0.000
Q50-Q56 Congenital malformations of genital organs
0.659 0.341 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.659 0.341 0.000
E87.4 Mixed disorder of acid-base balance
0.659 0.341 0.000
R82 Other abnormal findings in urine
0.659 0.341 0.000
W10 Fall on and from stairs and steps
0.659 0.341 0.000
Z60.2 Living alone
0.659 0.341 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.659 0.341 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.659 0.341 0.000
F70-F79 Mental retardation
0.659 0.341 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.658 0.342 0.000
F80-F89 Disorders of psychological development
0.658 0.342 0.000
C80 Malignant neoplasm without specification of site
0.658 0.342 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.658 0.342 0.000
H35 Other retinal disorders
0.657 0.343 0.000
N18.5 Chronic kidney disease, stage 5
0.657 0.343 0.000
S32 Fracture of lumbar spine and pelvis
0.657 0.343 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.657 0.343 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.656 0.344 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.656 0.344 0.000
G93 Other disorders of brain
0.656 0.344 0.000
R27.8 Other and unspecified lack of coordination
0.656 0.344 0.000
K42 Umbilical hernia
0.655 0.345 0.000
S01.5 Open wound of lip and oral cavity
0.655 0.345 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.654 0.345 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.655 0.345 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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