TreeWAS – Variant ID: rs74608138

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter VII Diseases of the eye and adnexa	1.000	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.999	0.001
R30-R39 Symptoms and signs involving the urinary system	0.999	0.001
Chapter XV Pregnancy, childbirth and the puerperium	0.999	0.001
Chapter IX Diseases of the circulatory system	0.998	0.002
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.998	0.002
H30-H36 Disorders of choroid and retina	0.991	0.009
R39 Other symptoms and signs involving the urinary system	0.987	0.013
O60-O75 Complications of labour and delivery	0.985	0.015
Chapter IV Endocrine, nutritional and metabolic diseases	0.982	0.018
Chapter XIV Diseases of the genitourinary system	0.982	0.018
Chapter II Neoplasms	0.981	0.019
S00-S09 Injuries to the head	0.978	0.022
H33 Retinal detachments and breaks	0.977	0.023
Chapter XXI Factors influencing health status and contact with health services	0.972	0.028
D10-D36 Benign neoplasms	0.970	0.030
R39.8 Other and unspecified symptoms and signs involving the urinary system	0.969	0.031
R31 Unspecified haematuria	0.968	0.032
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.967	0.033
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.965	0.035
H53-H54 Visual disturbances and blindness	0.961	0.039
Z40-Z54 Persons encountering health services for specific procedures and health care	0.960	0.040
Z46 Fitting and adjustment of other devices	0.958	0.042
I60-I69 Cerebrovascular diseases	0.957	0.043
Z46.6 Fitting and adjustment of urinary device	0.956	0.044
H40-H42 Glaucoma	0.953	0.047
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.949	0.051
O72 Postpartum haemorrhage	0.944	0.056
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.940	0.060
Chapter V Mental and behavioural disorders	0.939	0.061
N10-N16 Renal tubulo-interstitial diseases	0.935	0.065
D69 Purpura and other haemorrhagic conditions	0.929	0.071
I95-I99 Other and unspecified disorders of the circulatory system	0.929	0.071
R30 Pain associated with micturition	0.928	0.072
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.928	0.072
Z51 Other medical care	0.927	0.073
H53 Visual disturbances	0.925	0.075
E70-E90 Metabolic disorders	0.921	0.079
H40 Glaucoma	0.920	0.080
O70 Perineal laceration during delivery	0.913	0.087
N30-N39 Other diseases of urinary system	0.912	0.088
Chapter I Certain infectious and parasitic diseases	0.910	0.090
I26 Pulmonary embolism	0.907	0.093
N13 Obstructive and reflux uropathy	0.906	0.094
D69.6 Thrombocytopenia, unspecified	0.904	0.096
S00 Superficial injury of head	0.903	0.097
S09 Other and unspecified injuries of head	0.903	0.097
Z51.5 Palliative care	0.901	0.099
H40.9 Glaucoma, unspecified	0.899	0.101
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.899	0.101
R33 Retention of urine	0.898	0.102
O20-O29 Other maternal disorders predominantly related to pregnancy	0.896	0.104
I30-I52 Other forms of heart disease	0.896	0.104
R03 Abnormal blood-pressure reading, without diagnosis	0.891	0.109
N17-N19 Renal failure	0.890	0.110
N00-N08 Glomerular diseases	0.884	0.116
H33.0 Retinal detachment with retinal break	0.884	0.116
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.883	0.117
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.883	0.117
H33.3 Retinal breaks without detachment	0.883	0.117
R47-R49 Symptoms and signs involving speech and voice	0.881	0.119
Z51.8 Other specified medical care	0.878	0.122
R30.0 Dysuria	0.877	0.123
I69 Sequelae of cerebrovascular disease	0.875	0.125
E20-E35 Disorders of other endocrine glands	0.874	0.126
E78.5 Hyperlipidaemia, unspecified	0.872	0.128
D12.8 Rectum	0.871	0.129
O72.1 Other immediate postpartum haemorrhage	0.869	0.131
H33.2 Serous retinal detachment	0.869	0.131
S00.0 Superficial injury of scalp	0.863	0.137
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.862	0.138
D23 Other benign neoplasms of skin	0.859	0.141
H53.8 Other visual disturbances	0.858	0.142
F30-F39 Mood [affective] disorders	0.858	0.142
R02 Gangrene, not elsewhere classified	0.858	0.142
I70-I79 Diseases of arteries, arterioles and capillaries	0.855	0.145
R39.1 Other difficulties with micturition	0.852	0.148
H55-H59 Other disorders of eye and adnexa	0.852	0.148
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.851	0.149
S09.9 Unspecified injury of head	0.849	0.151
E00-E07 Disorders of thyroid gland	0.848	0.152
H34 Retinal vascular occlusions	0.846	0.153
O72.2 Delayed and secondary postpartum haemorrhage	0.846	0.154
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.846	0.154
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.845	0.155
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.843	0.157
S50-S59 Injuries to the elbow and forearm	0.842	0.158
N30 Cystitis	0.839	0.161
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.839	0.161
O80-O84 Delivery	0.836	0.164
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.836	0.164
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension	0.836	0.164
O26 Maternal care for other conditions predominantly related to pregnancy	0.835	0.165
D12.0 Caecum	0.834	0.166
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.828	0.172
N19 Unspecified renal failure	0.828	0.172
I95 Hypotension	0.827	0.173
R00 Abnormalities of heart beat	0.827	0.173
Z70-Z76 Persons encountering health services in other circumstances	0.826	0.174
D14 Benign neoplasm of middle ear and respiratory system	0.825	0.175
E50-E64 Other nutritional deficiencies	0.824	0.176
H53.4 Visual field defects	0.823	0.177
H31 Other disorders of choroid	0.820	0.180
E89.0 Postprocedural hypothyroidism	0.820	0.180
I34 Nonrheumatic mitral valve disorders	0.818	0.182
O70.0 First degree perineal laceration during delivery	0.816	0.184
I63 Cerebral infarction	0.816	0.184
D11 Benign neoplasm of major salivary glands	0.815	0.185
S80-S89 Injuries to the knee and lower leg	0.815	0.185
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.812	0.188
F31 Bipolar affective disorder	0.811	0.189
Z50 Care involving use of rehabilitation procedures	0.810	0.190
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.809	0.191
I60 Subarachnoid haemorrhage	0.808	0.192
N03 Chronic nephritic syndrome	0.807	0.193
H43-H45 Disorders of vitreous body and globe	0.805	0.195
S40-S49 Injuries to the shoulder and upper arm	0.804	0.196
H10-H13 Disorders of conjunctiva	0.803	0.197
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.802	0.198
O00-O08 Pregnancy with abortive outcome	0.800	0.200
N13.3 Other and unspecified hydronephrosis	0.798	0.201
D00-D09 In situ neoplasms	0.798	0.201
B95-B98 Bacterial, viral and other infectious agents	0.798	0.202
R00.1 Bradycardia, unspecified	0.797	0.203
A30-A49 Other bacterial diseases	0.794	0.206
I80 Phlebitis and thrombophlebitis	0.793	0.207
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.793	0.207
R07 Pain in throat and chest	0.793	0.207
I51 Complications and ill-defined descriptions of heart disease	0.788	0.212
Z51.1 Chemotherapy session for neoplasm	0.787	0.213
D69.3 Idiopathic thrombocytopenic purpura	0.786	0.214
D23.7 Skin of lower limb, including hip	0.786	0.214
O64 Obstructed labour due to malposition and malpresentation of foetus	0.783	0.217
O94-O99 Other obstetric conditions, not elsewhere classified	0.781	0.219
I62 Other nontraumatic intracranial haemorrhage	0.780	0.220
I69.3 Sequelae of cerebral infarction	0.779	0.221
N32 Other disorders of bladder	0.776	0.224
S06 Intracranial injury	0.775	0.224
D22 Melanocytic naevi	0.775	0.225
I99 Other and unspecified disorders of circulatory system	0.775	0.225
N13.4 Hydroureter	0.774	0.226
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.772	0.228
R34 Anuria and oliguria	0.770	0.230
D35 Benign neoplasm of other and unspecified endocrine glands	0.769	0.231
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.765	0.235
O62 Abnormalities of forces of labour	0.764	0.235
D68 Other coagulation defects	0.764	0.236
C79 Secondary malignant neoplasm of other sites	0.763	0.237
E04 Other non-toxic goitre	0.763	0.237
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.762	0.238
Chapter VI Diseases of the nervous system	0.762	0.238
E88 Other metabolic disorders	0.756	0.244
H33.5 Other retinal detachments	0.755	0.245
N36 Other disorders of urethra	0.755	0.245
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.755	0.245
H54 Blindness and low vision	0.754	0.246
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.753	0.247
D17 Benign lipomatous neoplasm	0.752	0.248
N03.9 Unspecified	0.752	0.248
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.751	0.248
C32 Malignant neoplasm of larynx	0.750	0.250
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.750	0.250
D10 Benign neoplasm of mouth and pharynx	0.750	0.250
H46-H48 Disorders of optic nerve and visual pathways	0.750	0.250
O26.9 Pregnancy-related condition, unspecified	0.749	0.251
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.748	0.252
R49 Voice disturbances	0.748	0.252
I46 Cardiac arrest	0.746	0.254
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.746	0.254
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.744	0.256
I95.9 Hypotension, unspecified	0.744	0.256
O73 Retained placenta and membranes, without haemorrhage	0.743	0.257
E65-E68 Obesity and other hyperalimentation	0.743	0.257
D12.2 Ascending colon	0.742	0.258
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.736	0.264
D60-D64 Aplastic and other anaemias	0.734	0.266
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses	0.734	0.266
B35-B49 Mycoses	0.732	0.268
S00.1 Contusion of eyelid and periocular area	0.732	0.268
O70.1 Second degree perineal laceration during delivery	0.732	0.268
D28 Benign neoplasm of other and unspecified female genital organs	0.731	0.268
I71 Aortic aneurysm and dissection	0.731	0.269
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.730	0.270
D33 Benign neoplasm of brain and other parts of central nervous system	0.729	0.271
R35 Polyuria	0.728	0.272
F99-F99 Unspecified mental disorder	0.727	0.273
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.726	0.274
S20-S29 Injuries to the thorax	0.726	0.274
H35 Other retinal disorders	0.725	0.275
N70-N77 Inflammatory diseases of female pelvic organs	0.725	0.275
T85 Complications of other internal prosthetic devices, implants and grafts	0.725	0.275
T66-T78 Other and unspecified effects of external causes	0.725	0.275
S01 Open wound of head	0.725	0.275
Z48 Other surgical follow-up care	0.724	0.276
R47 Speech disturbances, not elsewhere classified	0.721	0.279
D14.1 Larynx	0.721	0.279
D06 Carcinoma in situ of cervix uteri	0.721	0.279
D34 Benign neoplasm of thyroid gland	0.720	0.280
I33 Acute and subacute endocarditis	0.720	0.280
D12.3 Transverse colon	0.719	0.281
H53.9 Visual disturbance, unspecified	0.719	0.281
N30.3 Trigonitis	0.719	0.281
D12.9 Anus and anal canal	0.718	0.282
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
Z49 Care involving dialysis	0.717	0.283
R95-R99 Ill-defined and unknown causes of mortality	0.717	0.283
R36 Urethral discharge	0.716	0.283
O85-O92 Complications predominantly related to the puerperium	0.716	0.284
N34 Urethritis and urethral syndrome	0.716	0.284
O26.8 Other specified pregnancy-related conditions	0.716	0.284
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.716	0.284
I00-I02 Acute rheumatic fever	0.716	0.284
H34.8 Other retinal vascular occlusions	0.716	0.284
N13.5 Kinking and stricture of ureter without hydronephrosis	0.716	0.284
T79-T79 Certain early complications of trauma	0.715	0.284
T33-T35 Frostbite	0.715	0.284
T26-T28 Burns and corrosions confined to eye and internal organs	0.715	0.284
T20-T25 Burns and corrosions of external body surface, specified by site	0.715	0.284
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.715	0.284
T00-T07 Injuries involving multiple body regions	0.715	0.284
S10-S19 Injuries to the neck	0.715	0.284
T87 Complications peculiar to reattachment and amputation	0.715	0.285
O70.9 Perineal laceration during delivery, unspecified	0.715	0.285
I34.1 Mitral (valve) prolapse	0.714	0.286
Z50.0 Cardiac rehabilitation	0.712	0.288
I98 Other disorders of circulatory system in diseases classified elsewhere	0.712	0.288
I45 Other conduction disorders	0.712	0.288
C15-C26 Malignant neoplasms of digestive organs	0.712	0.288
D36 Benign neoplasm of other and unspecified sites	0.711	0.289
H32 Chorioretinal disorders in diseases classified elsewhere	0.710	0.289
H30 Chorioretinal inflammation	0.710	0.289
D37-D48 Neoplasms of uncertain or unknown behaviour	0.710	0.289
O66 Other obstructed labour	0.710	0.290
D23.2 Skin of ear and external auricular canal	0.709	0.291
F40-F48 Neurotic, stress-related and somatoform disorders	0.708	0.292
R39.2 Extrarenal uraemia	0.708	0.292
R39.0 Extravasation of urine	0.708	0.292
O74 Complications of anaesthesia during labour and delivery	0.706	0.294
O71 Other obstetric trauma	0.706	0.294
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.706	0.294
O65 Obstructed labour due to maternal pelvic abnormality	0.706	0.294
O61 Failed induction of labour	0.706	0.294
O60 Preterm delivery	0.706	0.294
Z50.1 Other physical therapy	0.706	0.294
E40-E46 Malnutrition	0.704	0.295
I51.8 Other ill-defined heart diseases	0.704	0.296
D11.0 Parotid gland	0.704	0.296
N13.8 Other obstructive and reflux uropathy	0.704	0.296
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.703	0.296
C40-C41 Malignant neoplasms of bone and articular cartilage	0.703	0.296
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.703	0.296
T88 Other complications of surgical and medical care, not elsewhere classified	0.702	0.298
I69.1 Sequelae of intracerebral haemorrhage	0.702	0.298
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.702	0.298
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.701	0.298
D70-D77 Other diseases of blood and blood-forming organs	0.701	0.298
S08 Traumatic amputation of part of head	0.701	0.299
S07 Crushing injury of head	0.701	0.299
S05 Injury of eye and orbit	0.701	0.299
S04 Injury of cranial nerves	0.701	0.299
S03 Dislocation, sprain and strain of joints and ligaments of head	0.701	0.299
N99-N99 Other disorders of the genitourinary system	0.701	0.299
B90-B94 Sequelae of infectious and parasitic diseases	0.701	0.299
H33.4 Traction detachment of retina	0.700	0.299
H33.1 Retinoschisis and retinal cysts	0.700	0.299
S51 Open wound of forearm	0.700	0.300
Chapter XXII Codes for special purposes	0.700	0.300
S90-S99 Injuries to the ankle and foot	0.700	0.300
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.700	0.300
H31.0 Chorioretinal scars	0.698	0.302
N10 Acute tubulo-interstitial nephritis	0.698	0.302
A49 Bacterial infection of unspecified site	0.698	0.302
E27 Other disorders of adrenal gland	0.697	0.303
D21 Other benign neoplasms of connective and other soft tissue	0.696	0.304
D31 Benign neoplasm of eye and adnexa	0.696	0.304
D30 Benign neoplasm of urinary organs	0.696	0.304
D29 Benign neoplasm of male genital organs	0.696	0.304
D26 Other benign neoplasms of uterus	0.696	0.304
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.696	0.304
D19 Benign neoplasm of mesothelial tissue	0.696	0.304
D16 Benign neoplasm of bone and articular cartilage	0.696	0.304
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.696	0.304
O75 Other complications of labour and delivery, not elsewhere classified	0.696	0.304
D27 Benign neoplasm of ovary	0.696	0.304
I34.0 Mitral (valve) insufficiency	0.696	0.304
H57 Other disorders of eye and adnexa	0.695	0.305
N30.8 Other cystitis	0.695	0.305
Chapter XII Diseases of the skin and subcutaneous tissue	0.694	0.306
D55-D59 Haemolytic anaemias	0.694	0.306
I47 Paroxysmal tachycardia	0.693	0.307
E26 Hyperaldosteronism	0.693	0.307
S80 Superficial injury of lower leg	0.693	0.307
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.692	0.308
S02 Fracture of skull and facial bones	0.692	0.308
T80 Complications following infusion, transfusion and therapeutic injection	0.691	0.309
H40.2 Primary angle-closure glaucoma	0.691	0.309
T81 Complications of procedures, not elsewhere classified	0.691	0.309
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.690	0.309
N20-N23 Urolithiasis	0.690	0.310
I61 Intracerebral haemorrhage	0.690	0.310
N18 Chronic renal failure	0.689	0.311
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.688	0.312
H53.2 Diplopia	0.688	0.312
Z54 Convalescence	0.688	0.312
Z44 Fitting and adjustment of external prosthetic device	0.688	0.312
Z73 Problems related to life-management difficulty	0.687	0.313
Z46.9 Fitting and adjustment of other unspecified device	0.687	0.313
Z46.8 Fitting and adjustment of other specified devices	0.687	0.313
Z46.7 Fitting and adjustment of orthopaedic device	0.687	0.313
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances	0.687	0.313
Z46.4 Fitting and adjustment of orthodontic device	0.687	0.313
Z46.3 Fitting and adjustment of dental prosthetic device	0.687	0.313
Z46.1 Fitting and adjustment of hearing aid	0.687	0.313
Z46.0 Fitting and adjustment of spectacles and contact lenses	0.687	0.313
I68 Cerebrovascular disorders in diseases classified elsewhere	0.686	0.314
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.686	0.314
R07.1 Chest pain on breathing	0.686	0.314
E05 Thyrotoxicosis [hyperthyroidism]	0.686	0.314
O47 False labour	0.686	0.314
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.686	0.314
O32 Maternal care for known or suspected malpresentation of foetus	0.685	0.315
N32.8 Other specified disorders of bladder	0.684	0.316
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.684	0.316
S00.3 Superficial injury of nose	0.683	0.317
H42 Glaucoma in diseases classified elsewhere	0.683	0.317
F33 Recurrent depressive disorder	0.683	0.317
O82 Single delivery by Caesarean section	0.682	0.318
H40.0 Glaucoma suspect	0.682	0.318
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.682	0.318
O69 Labour and delivery complicated by umbilical cord complications	0.681	0.318
E29 Testicular dysfunction	0.681	0.318
E61 Deficiency of other nutrient elements	0.681	0.319
D67 Hereditary factor IX deficiency	0.680	0.320
D66 Hereditary factor VIII deficiency	0.680	0.320
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.680	0.320
E78.8 Other disorders of lipoprotein metabolism	0.679	0.320
N30.9 Cystitis, unspecified	0.679	0.321
T15-T19 Effects of foreign body entering through natural orifice	0.678	0.321
Chapter XX External causes of morbidity and mortality	0.678	0.322
F60-F69 Disorders of adult personality and behaviour	0.678	0.322
O72.3 Postpartum coagulation defects	0.677	0.323
F31.0 Bipolar affective disorder, current episode hypomanic	0.677	0.323
G90-G99 Other disorders of the nervous system	0.676	0.324
T92 Sequelae of injuries of upper limb	0.676	0.324
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.676	0.324
I77 Other disorders of arteries and arterioles	0.676	0.324
N25-N29 Other disorders of kidney and ureter	0.675	0.325
C73 Malignant neoplasm of thyroid gland	0.674	0.326
I28 Other diseases of pulmonary vessels	0.674	0.326
N13.9 Obstructive and reflux uropathy, unspecified	0.674	0.326
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.673	0.327
F80-F89 Disorders of psychological development	0.673	0.327
F70-F79 Mental retardation	0.673	0.327
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.673	0.327
R93 Abnormal findings on diagnostic imaging of other body structures	0.673	0.327
N08 Glomerular disorders in diseases classified elsewhere	0.672	0.327
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.672	0.328
E28 Ovarian dysfunction	0.671	0.329
D12.7 Rectosigmoid junction	0.671	0.329
D17.5 Benign lipomatous neoplasm of intra-abdominal organs	0.671	0.329
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.670	0.330
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.670	0.330
N15 Other renal tubulo-interstitial diseases	0.670	0.330
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.670	0.330
N11 Chronic tubulo-interstitial nephritis	0.670	0.330
E78.2 Mixed hyperlipidaemia	0.668	0.332
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.667	0.333
D69.9 Haemorrhagic condition, unspecified	0.666	0.334
D69.8 Other specified haemorrhagic conditions	0.666	0.334
D69.5 Secondary thrombocytopenia	0.666	0.334
D69.4 Other primary thrombocytopenia	0.666	0.334
D69.2 Other nonthrombocytopenic purpura	0.666	0.334
D69.1 Qualitative platelet defects	0.666	0.334
D69.0 Allergic purpura	0.666	0.334
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.666	0.334
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.666	0.334
D22.4 Melanocytic naevi of scalp and neck	0.666	0.334
T90 Sequelae of injuries of head	0.666	0.334
D06.9 Cervix, unspecified	0.666	0.334
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.665	0.335
R30.9 Painful micturition, unspecified	0.665	0.335
R30.1 Vesical tenesmus	0.665	0.335
D12.1 Appendix	0.665	0.335
Z51.9 Medical care, unspecified	0.665	0.335
Z51.6 Desensitisation to allergens	0.665	0.335
H53.6 Night blindness	0.663	0.336
H53.5 Colour vision deficiencies	0.663	0.336
H53.3 Other disorders of binocular vision	0.663	0.336
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.663	0.337
R07.2 Precordial pain	0.663	0.337
Q80-Q89 Other congenital malformations	0.662	0.338
D18 Haemangioma and lymphangioma, any site	0.662	0.338
B15-B19 Viral hepatitis	0.662	0.338
N32.3 Diverticulum of bladder	0.662	0.338
H11 Other disorders of conjunctiva	0.661	0.339
H43 Disorders of vitreous body	0.661	0.339
T63 Toxic effect of contact with venomous animals	0.661	0.339
Z41 Procedures for purposes other than remedying health state	0.660	0.339
E85 Amyloidosis	0.660	0.340
E84 Cystic fibrosis	0.660	0.340
E79 Disorders of purine and pyrimidine metabolism	0.660	0.340
E77 Disorders of glycoprotein metabolism	0.660	0.340
E76 Disorders of glycosaminoglycan metabolism	0.660	0.340
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.660	0.340
E74 Other disorders of carbohydrate metabolism	0.660	0.340
E73 Lactose intolerance	0.660	0.340
E72 Other disorders of amino-acid metabolism	0.660	0.340
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.660	0.340
E70 Disorders of aromatic amino-acid metabolism	0.660	0.340
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.660	0.340
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.659	0.341
I72 Other aneurysm	0.659	0.341
H40.8 Other glaucoma	0.659	0.341
H40.6 Glaucoma secondary to drugs	0.659	0.341
H40.5 Glaucoma secondary to other eye disorders	0.659	0.341
H40.4 Glaucoma secondary to eye inflammation	0.659	0.341
H40.3 Glaucoma secondary to eye trauma	0.659	0.341
H53.1 Subjective visual disturbances	0.658	0.342
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.658	0.342
Z52 Donors of organs and tissues	0.658	0.342
I46.9 Cardiac arrest, unspecified	0.658	0.342
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.658	0.342
A50-A64 Infections with a predominantly sexual mode of transmission	0.657	0.343
O80 Single spontaneous delivery	0.657	0.343
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.657	0.343
H34.2 Other retinal artery occlusions	0.657	0.343
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck	0.656	0.344
O72.0 Third-stage haemorrhage	0.655	0.345
O70.3 Fourth degree perineal laceration during delivery	0.654	0.345
O70.2 Third degree perineal laceration during delivery	0.654	0.345
S42 Fracture of shoulder and upper arm	0.654	0.345
N37 Urethral disorders in diseases classified elsewhere	0.654	0.346
N33 Bladder disorders in diseases classified elsewhere	0.654	0.346
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.653	0.346
D22.7 Melanocytic naevi of lower limb, including hip	0.653	0.347
T59 Toxic effect of other gases, fumes and vapours	0.653	0.347
R03.1 Nonspecific low blood-pressure reading	0.653	0.347
R49.0 Dysphonia	0.652	0.348
B99-B99 Other infectious diseases	0.652	0.348
B85-B89 Pediculosis, acariasis and other infestations	0.652	0.348
B65-B83 Helminthiases	0.652	0.348
B50-B64 Protozoal diseases	0.652	0.348
B20-B24 Human immunodeficiency virus [HIV] disease	0.652	0.348
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.652	0.348
A80-A89 Viral infections of the central nervous system	0.652	0.348
A75-A79 Rickettsioses	0.652	0.348
A70-A74 Other diseases caused by chlamydiae	0.652	0.348
A65-A69 Other spirochaetal diseases	0.652	0.348
A20-A28 Certain zoonotic bacterial diseases	0.652	0.348
A15-A19 Tuberculosis	0.652	0.348
O02 Other abnormal products of conception	0.652	0.348
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.650	0.350
Q38-Q45 Other congenital malformations of the digestive system	0.650	0.350
F20 Schizophrenia	0.650	0.350
N13.7 Vesicoureteral-reflux-associated uropathy	0.649	0.350
N13.6 Pyonephrosis	0.649	0.350
N36.8 Other specified disorders of urethra	0.649	0.351
T91 Sequelae of injuries of neck and trunk	0.649	0.351
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.649	0.351
F25 Schizoaffective disorders	0.648	0.352
S00.7 Multiple superficial injuries of head	0.648	0.352
S00.5 Superficial injury of lip and oral cavity	0.648	0.352
S00.4 Superficial injury of ear	0.648	0.352
S00.2 Other superficial injuries of eyelid and periocular area	0.648	0.352
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.648	0.352
S09.8 Other specified injuries of head	0.647	0.352
S09.7 Multiple injuries of head	0.647	0.352
S09.2 Traumatic rupture of ear drum	0.647	0.352
S09.1 Injury of muscle and tendon of head	0.647	0.352
S09.0 Injury of blood vessels of head, not elsewhere classified	0.647	0.352
R04 Haemorrhage from respiratory passages	0.647	0.353
I30 Acute pericarditis	0.646	0.354
T31 Burns classified according to extent of body surface involved	0.646	0.354
D50-D53 Nutritional anaemias	0.645	0.355
N05 Unspecified nephritic syndrome	0.645	0.355
T86 Failure and rejection of transplanted organs and tissues	0.644	0.356
O68 Labour and delivery complicated by foetal stress [distress]	0.644	0.356
O41 Other disorders of amniotic fluid and membranes	0.644	0.356
S70-S79 Injuries to the hip and thigh	0.644	0.356
L00-L08 Infections of the skin and subcutaneous tissue	0.643	0.357
O29 Complications of anaesthesia during pregnancy	0.642	0.357
O28 Abnormal findings on antenatal screening of mother	0.642	0.357
O24 Diabetes mellitus in pregnancy	0.642	0.357
O23 Infections of genito-urinary tract in pregnancy	0.642	0.357
O22 Venous complications in pregnancy	0.642	0.357
O21 Excessive vomiting in pregnancy	0.642	0.357
O25 Malnutrition in pregnancy	0.642	0.357
I52 Other heart disorders in diseases classified elsewhere	0.642	0.358
I48 Atrial fibrillation and flutter	0.642	0.358
I43 Cardiomyopathy in diseases classified elsewhere	0.642	0.358
I41 Myocarditis in diseases classified elsewhere	0.642	0.358
I40 Acute myocarditis	0.642	0.358
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.642	0.358
I37 Pulmonary valve disorders	0.642	0.358
I36 Nonrheumatic tricuspid valve disorders	0.642	0.358
I32 Pericarditis in diseases classified elsewhere	0.642	0.358
D23.6 Skin of upper limb, including shoulder	0.642	0.358
Z63 Other problems related to primary support group, including family circumstances	0.640	0.360
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.640	0.360

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations