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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74617384
log Bayes Factor = 405.131
Chromosome 6   position 160,997,118  (GRCh37) Explore rs74617384 on Ensembl!
Variant rs74617384 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E78.5 Hyperlipidaemia, unspecified
1.000 0.000 0.000
E78.0 Pure hypercholesterolaemia
1.000 0.000 0.000
I20.9 Angina pectoris, unspecified
1.000 0.000 0.000
I20.0 Unstable angina
1.000 0.000 0.000
I21.9 Acute myocardial infarction, unspecified
1.000 0.000 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
1.000 0.000 0.000
I25.9 Chronic ischaemic heart disease, unspecified
1.000 0.000 0.000
I25.8 Other forms of chronic ischaemic heart disease
1.000 0.000 0.000
I25.2 Old myocardial infarction
1.000 0.000 0.000
I25.1 Atherosclerotic heart disease
1.000 0.000 0.000
I35.0 Aortic (valve) stenosis
1.000 0.000 0.000
I73.9 Peripheral vascular disease, unspecified
1.000 0.000 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
1.000 0.000 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
1.000 0.000 0.000
Z95.5 Presence of coronary angioplasty implant and graft
1.000 0.000 0.000
Z95.1 Presence of aortocoronary bypass graft
1.000 0.000 0.000
I10 Essential (primary) hypertension
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I21 Acute myocardial infarction
1.000 0.000 0.000
I20 Angina pectoris
1.000 0.000 0.000
I35 Nonrheumatic aortic valve disorders
1.000 0.000 0.000
Z95 Presence of cardiac and vascular implants and grafts
1.000 0.000 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I20.8 Other forms of angina pectoris
1.000 0.000 0.000
I60-I69 Cerebrovascular diseases
1.000 0.000 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
1.000 0.000 0.000
I77.1 Stricture of artery
1.000 0.000 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
1.000 0.000 0.000
I22 Subsequent myocardial infarction
1.000 0.000 0.000
I77 Other disorders of arteries and arterioles
1.000 0.000 0.000
I73 Other peripheral vascular diseases
1.000 0.000 0.000
I10-I15 Hypertensive diseases
1.000 0.000 0.000
I50 Heart failure
1.000 0.000 0.000
I74 Arterial embolism and thrombosis
1.000 0.000 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
1.000 0.000 0.000
I65.2 Occlusion and stenosis of carotid artery
0.999 0.001 0.000
I24 Other acute ischaemic heart diseases
0.999 0.001 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.999 0.001 0.000
I50.1 Left ventricular failure
0.999 0.001 0.000
I21.4 Acute subendocardial myocardial infarction
0.998 0.002 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.998 0.002 0.000
I70 Atherosclerosis
0.996 0.004 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.995 0.005 0.000
I44 Atrioventricular and left bundle-branch block
0.994 0.006 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.992 0.008 0.000
I71 Aortic aneurysm and dissection
0.990 0.010 0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.989 0.011 0.000
I51 Complications and ill-defined descriptions of heart disease
0.988 0.012 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.988 0.012 0.000
Z95.3 Presence of xenogenic heart valve
0.986 0.014 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.985 0.015 0.000
I35.1 Aortic (valve) insufficiency
0.984 0.016 0.000
I51.8 Other ill-defined heart diseases
0.983 0.017 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.973 0.027 0.000
I44.0 Atrioventricular block, first degree
0.972 0.028 0.000
I63 Cerebral infarction
0.969 0.031 0.000
I05-I09 Chronic rheumatic heart diseases
0.968 0.032 0.000
I31 Other diseases of pericardium
0.966 0.034 0.000
Z95.0 Presence of cardiac pacemaker
0.966 0.034 0.000
I44.7 Left bundle-branch block, unspecified
0.964 0.036 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.963 0.037 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.962 0.038 0.000
I63.9 Cerebral infarction, unspecified
0.958 0.042 0.000
I08 Multiple valve diseases
0.956 0.044 0.000
I46 Cardiac arrest
0.954 0.046 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.952 0.048 0.000
I24.8 Other forms of acute ischaemic heart disease
0.950 0.050 0.000
I35.9 Aortic valve disorder, unspecified
0.944 0.056 0.000
I31.9 Disease of pericardium, unspecified
0.937 0.063 0.000
I46.0 Cardiac arrest with successful resuscitation
0.936 0.064 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.930 0.070 0.000
I50.9 Heart failure, unspecified
0.930 0.070 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.927 0.073 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.926 0.074 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.925 0.075 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.907 0.093 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.903 0.097 0.000
I25.5 Ischaemic cardiomyopathy
0.902 0.098 0.000
I22.8 Subsequent myocardial infarction of other sites
0.896 0.104 0.000
Z92 Personal history of medical treatment
0.892 0.108 0.000
Z95.4 Presence of other heart-valve replacement
0.889 0.111 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.882 0.118 0.000
I08.0 Disorders of both mitral and aortic valves
0.875 0.125 0.000
I72 Other aneurysm
0.870 0.130 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.867 0.133 0.000
I44.6 Other and unspecified fascicular block
0.864 0.136 0.000
I60 Subarachnoid haemorrhage
0.863 0.137 0.000
I08.8 Other multiple valve diseases
0.861 0.139 0.000
I77.2 Rupture of artery
0.848 0.152 0.000
E78.4 Other hyperlipidaemia
0.847 0.152 0.000
I44.3 Other and unspecified atrioventricular block
0.847 0.153 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.844 0.156 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.843 0.157 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.827 0.173 0.000
I61 Intracerebral haemorrhage
0.811 0.189 0.000
E78.2 Mixed hyperlipidaemia
0.811 0.189 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.810 0.190 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.808 0.192 0.000
Chapter XXI Factors influencing health status and contact with health services
0.806 0.194 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.802 0.198 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.801 0.199 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.794 0.206 0.000
T82.3 Mechanical complication of other vascular grafts
0.793 0.207 0.000
I25.4 Coronary artery aneurysm
0.791 0.209 0.000
I38 Endocarditis, valve unspecified
0.789 0.211 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.786 0.214 0.000
I25.3 Aneurysm of heart
0.785 0.215 0.000
I77.0 Arteriovenous fistula, acquired
0.785 0.215 0.000
I70.0 Atherosclerosis of aorta
0.782 0.218 0.000
I11 Hypertensive heart disease
0.774 0.226 0.000
I23 Certain current complications following acute myocardial infarction
0.770 0.230 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.769 0.231 0.000
I36 Nonrheumatic tricuspid valve disorders
0.769 0.231 0.000
E70-E90 Metabolic disorders
0.766 0.234 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.765 0.235 0.000
I71.0 Dissection of aorta [any part]
0.764 0.236 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.764 0.236 0.000
# Top node
0.764 0.236 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.762 0.238 0.000
I72.4 Aneurysm of artery of lower extremity
0.760 0.240 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.759 0.241 0.000
I30 Acute pericarditis
0.759 0.241 0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.758 0.242 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.752 0.248 0.000
I63.8 Other cerebral infarction
0.751 0.249 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.748 0.252 0.000
I50.0 Congestive heart failure
0.747 0.253 0.000
Z63 Other problems related to primary support group, including family circumstances
0.745 0.255 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.745 0.255 0.000
I15 Secondary hypertension
0.744 0.256 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.742 0.258 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.741 0.259 0.000
S00-S09 Injuries to the head
0.739 0.261 0.000
I31.3 Pericardial effusion (noninflammatory)
0.737 0.263 0.000
I73.8 Other specified peripheral vascular diseases
0.731 0.269 0.000
E50-E64 Other nutritional deficiencies
0.728 0.272 0.000
Z82.2 Family history of deafness and hearing loss
0.723 0.276 0.000
Z92.8 Personal history of other medical treatment
0.722 0.278 0.000
S06 Intracranial injury
0.721 0.279 0.000
I47 Paroxysmal tachycardia
0.720 0.280 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.717 0.283 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
E78.6 Lipoprotein deficiency
0.717 0.283 0.000
E78.3 Hyperchylomicronaemia
0.717 0.283 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.717 0.283 0.000
I77.5 Necrosis of artery
0.717 0.283 0.000
I77.4 Coeliac artery compression syndrome
0.717 0.283 0.000
I77.3 Arterial fibromuscular dysplasia
0.717 0.283 0.000
I13 Hypertensive heart and renal disease
0.717 0.283 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.717 0.283 0.000
I74.8 Embolism and thrombosis of other arteries
0.717 0.283 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.717 0.283 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.717 0.283 0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.717 0.283 0.000
I65.8 Occlusion and stenosis of other precerebral artery
0.717 0.283 0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.717 0.283 0.000
I65.1 Occlusion and stenosis of basilar artery
0.717 0.283 0.000
I73.0 Raynaud's syndrome
0.717 0.283 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.716 0.283 0.000
I24.1 Dressler's syndrome
0.716 0.283 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.715 0.285 0.000
I70.9 Generalised and unspecified atherosclerosis
0.714 0.286 0.000
I70.8 Atherosclerosis of other arteries
0.714 0.286 0.000
I70.1 Atherosclerosis of renal artery
0.714 0.286 0.000
I35.8 Other aortic valve disorders
0.714 0.286 0.000
I44.5 Left posterior fascicular block
0.713 0.287 0.000
I44.4 Left anterior fascicular block
0.713 0.287 0.000
E53 Deficiency of other B group vitamins
0.711 0.289 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.710 0.290 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.710 0.290 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.710 0.290 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.710 0.290 0.000
I51.9 Heart disease, unspecified
0.709 0.291 0.000
I51.5 Myocardial degeneration
0.708 0.292 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.708 0.292 0.000
I51.0 Cardiac septal defect, acquired
0.708 0.292 0.000
I51.6 Cardiovascular disease, unspecified
0.705 0.295 0.000
I74.5 Embolism and thrombosis of iliac artery
0.704 0.296 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.701 0.299 0.000
E53.8 Deficiency of other specified B group vitamins
0.699 0.301 0.000
I72.3 Aneurysm of iliac artery
0.697 0.303 0.000
Z82.3 Family history of stroke
0.696 0.304 0.000
I45 Other conduction disorders
0.696 0.304 0.000
E78.1 Pure hyperglyceridaemia
0.695 0.304 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.695 0.305 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.695 0.305 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.695 0.305 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.695 0.305 0.000
I09 Other rheumatic heart diseases
0.694 0.306 0.000
I06 Rheumatic aortic valve diseases
0.694 0.306 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.694 0.306 0.000
I31.8 Other specified diseases of pericardium
0.693 0.307 0.000
I31.2 Haemopericardium, not elsewhere classified
0.693 0.307 0.000
I31.1 Chronic constrictive pericarditis
0.693 0.307 0.000
I31.0 Chronic adhesive pericarditis
0.693 0.307 0.000
T82.1 Mechanical complication of cardiac electronic device
0.692 0.307 0.000
I49 Other cardiac arrhythmias
0.688 0.312 0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.686 0.314 0.000
I08.9 Multiple valve disease, unspecified
0.686 0.314 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.685 0.315 0.000
I46.1 Sudden cardiac death, so described
0.684 0.316 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.681 0.319 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.679 0.321 0.000
I33 Acute and subacute endocarditis
0.677 0.323 0.000
I60.8 Other subarachnoid haemorrhage
0.675 0.325 0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)
0.674 0.326 0.000
Z72 Problems related to lifestyle
0.674 0.326 0.000
Z63.0 Problems in relationship with spouse or partner
0.672 0.328 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.669 0.331 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.668 0.332 0.000
E88 Other metabolic disorders
0.664 0.336 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.664 0.336 0.000
Z82.1 Family history of blindness and visual loss
0.664 0.336 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.664 0.336 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.662 0.337 0.000
Z75 Problems related to medical facilities and other health care
0.659 0.341 0.000
E65-E68 Obesity and other hyperalimentation
0.659 0.341 0.000
I47.2 Ventricular tachycardia
0.658 0.342 0.000
S10-S19 Injuries to the neck
0.653 0.347 0.000
S06.2 Diffuse brain injury
0.653 0.347 0.000
Z59 Problems related to housing and economic circumstances
0.651 0.349 0.000
Z73 Problems related to life-management difficulty
0.650 0.350 0.000
T92 Sequelae of injuries of upper limb
0.647 0.353 0.000
I61.8 Other intracerebral haemorrhage
0.647 0.353 0.000
S01 Open wound of head
0.645 0.355 0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.642 0.358 0.000
Z57 Occupational exposure to risk-factors
0.642 0.358 0.000
I62 Other nontraumatic intracranial haemorrhage
0.641 0.359 0.000
Z92.9 Personal history of medical treatment, unspecified
0.639 0.361 0.000
Z92.5 Personal history of rehabilitation measures
0.639 0.361 0.000
Z72.0 Tobacco use
0.639 0.361 0.000
E78.8 Other disorders of lipoprotein metabolism
0.638 0.362 0.000
I67 Other cerebrovascular diseases
0.638 0.362 0.000
I99 Other and unspecified disorders of circulatory system
0.637 0.363 0.000
Z94 Transplanted organ and tissue status
0.636 0.364 0.000
I72.8 Aneurysm of other specified arteries
0.633 0.367 0.000
Z56 Problems related to employment and unemployment
0.630 0.370 0.000
I70.00 Atherosclerosis of aorta (without gangrene)
0.629 0.371 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.626 0.374 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.626 0.374 0.000
I37 Pulmonary valve disorders
0.626 0.374 0.000
I72.9 Aneurysm of unspecified site
0.623 0.376 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.623 0.376 0.000
I72.5 Aneurysm and dissection of other precerebral arteries
0.623 0.376 0.000
I72.2 Aneurysm of renal artery
0.623 0.376 0.000
I72.1 Aneurysm of artery of upper extremity
0.623 0.376 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.621 0.379 0.000
S70-S79 Injuries to the hip and thigh
0.620 0.380 0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.619 0.381 0.000
I60.5 Subarachnoid haemorrhage from vertebral artery
0.619 0.381 0.000
I60.4 Subarachnoid haemorrhage from basilar artery
0.619 0.381 0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.619 0.381 0.000
Z89 Acquired absence of limb
0.615 0.385 0.000
I07 Rheumatic tricuspid valve diseases
0.613 0.387 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.613 0.387 0.000
I11.9 Hypertensive heart disease without (congestive) heart failure
0.611 0.389 0.000
S01.9 Open wound of head, part unspecified
0.609 0.391 0.000
Z97 Presence of other devices
0.609 0.391 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.607 0.393 0.000
I23.8 Other current complications following acute myocardial infarction
0.606 0.394 0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.605 0.395 0.000
Z84 Family history of other conditions
0.605 0.395 0.000
S90-S99 Injuries to the ankle and foot
0.605 0.395 0.000
S06.20 Diffuse brain injury (without open intracranial wound)
0.604 0.396 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.603 0.397 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.602 0.398 0.000
E66 Obesity
0.602 0.398 0.000
Z64 Problems related to certain psychosocial circumstances
0.602 0.398 0.000
Z73.9 Problem related to life-management difficulty, unspecified
0.600 0.400 0.000
Z63.8 Other specified problems related to primary support group
0.600 0.400 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.598 0.402 0.000
I77.6 Arteritis, unspecified
0.596 0.404 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.595 0.404 0.000
I49.0 Ventricular fibrillation and flutter
0.594 0.406 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.593 0.407 0.000
Z58 Problems related to physical environment
0.591 0.409 0.000
I34 Nonrheumatic mitral valve disorders
0.588 0.412 0.000
E66.9 Obesity, unspecified
0.585 0.415 0.000
I45.9 Conduction disorder, unspecified
0.584 0.416 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.583 0.417 0.000
Z75.2 Other waiting period for investigation and treatment
0.582 0.417 0.000
T00-T07 Injuries involving multiple body regions
0.582 0.418 0.000
I61.6 Intracerebral haemorrhage, multiple localised
0.582 0.418 0.000
I61.3 Intracerebral haemorrhage in brain stem
0.582 0.418 0.000
I05 Rheumatic mitral valve diseases
0.581 0.419 0.000
I95 Hypotension
0.578 0.422 0.000
Z63.5 Disruption of family by separation and divorce
0.577 0.422 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.577 0.423 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.574 0.426 0.000
I30.1 Infective pericarditis
0.574 0.426 0.000
Z63.6 Dependent relative needing care at home
0.574 0.426 0.000
E85 Amyloidosis
0.574 0.426 0.000
E51 Thiamine deficiency
0.572 0.428 0.000
T92.1 Sequelae of fracture of arm
0.571 0.429 0.000
S01.3 Open wound of ear
0.570 0.430 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.569 0.431 0.000
S50-S59 Injuries to the elbow and forearm
0.567 0.433 0.000
Z76 Persons encountering health services in other circumstances
0.565 0.435 0.000
S14 Injury of nerves and spinal cord at neck level
0.564 0.436 0.000
Z65 Problems related to other psychosocial circumstances
0.563 0.436 0.000
Z62 Other problems related to upbringing
0.563 0.436 0.000
Z61 Problems related to negative life events in childhood
0.563 0.436 0.000
Z55 Problems related to education and literacy
0.563 0.436 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.561 0.439 0.000
I70.01 Atherosclerosis of aorta (with gangrene)
0.561 0.439 0.000
Chapter XX External causes of morbidity and mortality
0.561 0.439 0.000
I15.1 Hypertension secondary to other renal disorders
0.560 0.440 0.000
I30.9 Acute pericarditis, unspecified
0.559 0.441 0.000
I72.0 Aneurysm of carotid artery
0.558 0.442 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.556 0.444 0.000
I49.4 Other and unspecified premature depolarisation
0.555 0.445 0.000
I11.0 Hypertensive heart disease with (congestive) heart failure
0.555 0.445 0.000
S01.8 Open wound of other parts of head
0.554 0.446 0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.553 0.446 0.000
E73 Lactose intolerance
0.553 0.447 0.000
I61.4 Intracerebral haemorrhage in cerebellum
0.552 0.447 0.000
Z63.4 Disappearance and death of family member
0.552 0.447 0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.552 0.448 0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.552 0.448 0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.552 0.448 0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.552 0.448 0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.552 0.448 0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.552 0.448 0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.552 0.448 0.000
T20 Burn and corrosion of head and neck
0.552 0.448 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.552 0.448 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.551 0.449 0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.551 0.449 0.000
I36.8 Other nonrheumatic tricuspid valve disorders
0.551 0.449 0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.551 0.449 0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.551 0.449 0.000
S05 Injury of eye and orbit
0.551 0.449 0.000
E84 Cystic fibrosis
0.549 0.451 0.000
E79 Disorders of purine and pyrimidine metabolism
0.549 0.451 0.000
E77 Disorders of glycoprotein metabolism
0.549 0.451 0.000
E76 Disorders of glycosaminoglycan metabolism
0.549 0.451 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.549 0.451 0.000
E72 Other disorders of amino-acid metabolism
0.549 0.451 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.549 0.451 0.000
E70 Disorders of aromatic amino-acid metabolism
0.549 0.451 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.549 0.451 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.548 0.452 0.000
I49.8 Other specified cardiac arrhythmias
0.547 0.453 0.000
I77.8 Other specified disorders of arteries and arterioles
0.546 0.454 0.000
T33-T35 Frostbite
0.544 0.455 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.544 0.455 0.000
I30.8 Other forms of acute pericarditis
0.544 0.456 0.000
I30.0 Acute nonspecific idiopathic pericarditis
0.544 0.456 0.000
S72 Fracture of femur
0.543 0.457 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.543 0.457 0.000
Z59.8 Other problems relating to housing and economic circumstances
0.542 0.458 0.000
I62.1 Nontraumatic extradural haemorrhage
0.541 0.459 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.540 0.460 0.000
S06.3 Focal brain injury
0.539 0.461 0.000
E40-E46 Malnutrition
0.539 0.461 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.539 0.461 0.000
I20.1 Angina pectoris with documented spasm
0.538 0.462 0.000
E74 Other disorders of carbohydrate metabolism
0.538 0.462 0.000
Z73.8 Other problems related to life-management difficulty
0.537 0.463 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.536 0.464 0.000
Z63.9 Problem related to primary support group, unspecified
0.534 0.466 0.000
Z63.7 Other stressful life events affecting family and household
0.534 0.466 0.000
Z63.3 Absence of family member
0.534 0.466 0.000
Z63.2 Inadequate family support
0.534 0.466 0.000
Z63.1 Problems in relationship with parents and in-laws
0.534 0.466 0.000
I15.9 Seconday hypertension, unspecified
0.533 0.467 0.000
I15.8 Other secondary hypertension
0.533 0.467 0.000
I15.2 Hypertension secondary to endocrine disorders
0.533 0.467 0.000
I15.0 Renovascular hypertension
0.533 0.467 0.000
Z94.1 Heart transplant status
0.533 0.467 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.532 0.467 0.000
Z94.2 Lung transplant status
0.532 0.468 0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.531 0.468 0.000
I79.1 Aortitis in diseases classified elsewhere
0.531 0.468 0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.531 0.468 0.000
Z57.8 Occupational exposure to other risk-factors
0.531 0.469 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.531 0.469 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.530 0.470 0.000
S08 Traumatic amputation of part of head
0.530 0.470 0.000
S07 Crushing injury of head
0.530 0.470 0.000
S04 Injury of cranial nerves
0.530 0.470 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.530 0.470 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.529 0.471 0.000
S00 Superficial injury of head
0.526 0.474 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.524 0.476 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.523 0.477 0.000
S06.8 Other intracranial injuries
0.523 0.477 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.522 0.478 0.000
E63 Other nutritional deficiencies
0.522 0.478 0.000
E56 Other vitamin deficiencies
0.522 0.478 0.000
E50 Vitamin A deficiency
0.522 0.478 0.000
E60 Dietary zinc deficiency
0.522 0.478 0.000
E59 Dietary selenium deficiency
0.522 0.478 0.000
E58 Dietary calcium deficiency
0.522 0.478 0.000
E54 Ascorbic acid deficiency
0.522 0.478 0.000
E52 Niacin deficiency [pellagra]
0.522 0.478 0.000
E88.2 Lipomatosis, not elsewhere classified
0.522 0.478 0.000
I51.4 Myocarditis, unspecified
0.519 0.480 0.000
Z81 Family history of mental and behavioural disorders
0.518 0.481 0.000
Z57.5 Occupational exposure to toxic agents in other industries
0.518 0.482 0.000
S06.9 Intracranial injury, unspecified
0.517 0.483 0.000
S06.7 Intracranial injury with prolonged coma
0.517 0.483 0.000
S06.1 Traumatic cerebral oedema
0.517 0.483 0.000
I67.9 Cerebrovascular disease, unspecified
0.517 0.483 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.516 0.484 0.000
I45.6 Preexcitation syndrome
0.515 0.485 0.000
I32.8 Pericarditis in other diseases classified elsewhere
0.514 0.486 0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.514 0.486 0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.514 0.486 0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.514 0.486 0.000
I39.4 Multiple valve disorders in diseases classified elsewhere
0.514 0.486 0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.514 0.486 0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.514 0.486 0.000
I39.1 Aortic valve disorders in diseases classified elsewhere
0.514 0.486 0.000
I39.0 Mitral valve disorders in diseases classified elsewhere
0.514 0.486 0.000
I40.9 Acute myocarditis, unspecified
0.514 0.486 0.000
I40.8 Other acute myocarditis
0.514 0.486 0.000
I40.1 Isolated myocarditis
0.514 0.486 0.000
I40.0 Infective myocarditis
0.514 0.486 0.000
I41.8 Myocarditis in other diseases classified elsewhere
0.514 0.486 0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.514 0.486 0.000
I41.1 Myocarditis in viral diseases classified elsewhere
0.514 0.486 0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.514 0.486 0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.514 0.486 0.000
I43.2 Cardiomyopathy in nutritional diseases
0.514 0.486 0.000
I43.1 Cardiomyopathy in metabolic diseases
0.514 0.486 0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.514 0.486 0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.514 0.486 0.000
I48.4 Atypical atrial flutter
0.514 0.486 0.000
I48.3 Typical atrial flutter
0.514 0.486 0.000
I48.2 Chronic atrial fibrillation
0.514 0.486 0.000
I48.1 Persistent atrial fibrillation
0.514 0.486 0.000
I48.0 Paroxysmal atrial fibrillation
0.514 0.486 0.000
I52.8 Other heart disorders in other diseases classified elsewhere
0.514 0.486 0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.514 0.486 0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.514 0.486 0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.514 0.486 0.000
I66.8 Occlusion and stenosis of other cerebral artery
0.514 0.486 0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.514 0.486 0.000
I66.3 Occlusion and stenosis of cerebellar arteries
0.514 0.486 0.000
I66.2 Occlusion and stenosis of posterior cerebral artery
0.514 0.486 0.000
I66.1 Occlusion and stenosis of anterior cerebral artery
0.514 0.486 0.000
I66.0 Occlusion and stenosis of middle cerebral artery
0.514 0.486 0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.514 0.486 0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.514 0.486 0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.514 0.486 0.000
I68.0 Cerebral amyloid angiopathy
0.514 0.486 0.000
I02 Rheumatic chorea
0.514 0.486 0.000
I01 Rheumatic fever with heart involvement
0.514 0.486 0.000
I00 Rheumatic fever without mention of heart involvement
0.514 0.486 0.000
I13.9 Hypertensive heart and renal disease, unspecified
0.514 0.486 0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.514 0.486 0.000
I13.1 Hypertensive heart and renal disease with renal failure
0.514 0.486 0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.514 0.486 0.000
I45.5 Other specified heart block
0.512 0.488 0.000
I70.81 Atherosclerosis of other arteries (with gangrene)
0.512 0.488 0.000
I70.80 Atherosclerosis of other arteries (without gangrene)
0.512 0.488 0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.512 0.488 0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.512 0.488 0.000
I70.11 Atherosclerosis of renal artery (with gangrene)
0.512 0.488 0.000
I70.10 Atherosclerosis of renal artery (without gangrene)
0.511 0.488 0.000
S50 Superficial injury of forearm
0.511 0.489 0.000
T92.8 Sequelae of other specified injuries of upper limb
0.511 0.489 0.000
E53.9 Vitamin B deficiency, unspecified
0.510 0.490 0.000
E53.1 Pyridoxine deficiency
0.510 0.490 0.000
E53.0 Riboflavin deficiency
0.510 0.490 0.000
S00.8 Superficial injury of other parts of head
0.510 0.490 0.000
Z75.1 Person awaiting admission to adequate facility elsewhere
0.510 0.490 0.000
T21 Burn and corrosion of trunk
0.508 0.492 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.508 0.492 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.507 0.493 0.000
Z94.7 Corneal transplant status
0.506 0.494 0.000
Z56.0 Unemployment, unspecified
0.503 0.497 0.000
Z75.8 Other problems related to medical facilities and other health care
0.502 0.498 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.501 0.499 0.000
I45.0 Right fascicular block
0.499 0.501 0.000
T13 Other injuries of lower limb, level unspecified
0.498 0.502 0.000
I06.9 Rheumatic aortic valve disease, unspecified
0.498 0.502 0.000
I06.8 Other rheumatic aortic valve diseases
0.498 0.502 0.000
I06.2 Rheumatic aortic stenosis with insufficiency
0.498 0.502 0.000
I06.1 Rheumatic aortic insufficiency
0.498 0.502 0.000
I06.0 Rheumatic aortic stenosis
0.498 0.502 0.000
I09.9 Rheumatic heart disease, unspecified
0.498 0.502 0.000
I09.8 Other specified rheumatic heart diseases
0.498 0.502 0.000
I09.2 Chronic rheumatic pericarditis
0.498 0.502 0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.498 0.502 0.000
I09.0 Rheumatic myocarditis
0.498 0.502 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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