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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74805376
log Bayes Factor = 13.9121
Chromosome 22   position 25,978,464  (GRCh37) Explore rs74805376 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
0.998 0.002 0.000
Chapter VI Diseases of the nervous system
0.998 0.002 0.000
E10-E14 Diabetes mellitus
0.998 0.002 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.987 0.013 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.986 0.014 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.980 0.020 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.979 0.021 0.000
Chapter VII Diseases of the eye and adnexa
0.977 0.023 0.000
E14 Unspecified diabetes mellitus
0.975 0.025 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.973 0.027 0.000
E11 Non-insulin-dependent diabetes mellitus
0.972 0.028 0.000
M05-M14 Inflammatory polyarthropathies
0.969 0.031 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.965 0.035 0.000
T81 Complications of procedures, not elsewhere classified
0.964 0.036 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.963 0.037 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.960 0.040 0.000
E14.9 Without complications
0.959 0.041 0.000
Chapter XXI Factors influencing health status and contact with health services
0.958 0.042 0.000
Z72 Problems related to lifestyle
0.957 0.043 0.000
Chapter XX External causes of morbidity and mortality
0.956 0.044 0.000
E70-E90 Metabolic disorders
0.955 0.045 0.000
Chapter IX Diseases of the circulatory system
0.935 0.065 0.000
Z72.0 Tobacco use
0.926 0.074 0.000
Z72.1 Alcohol use
0.924 0.076 0.000
M13 Other arthritis
0.924 0.076 0.000
F30-F39 Mood [affective] disorders
0.909 0.091 0.000
M07 Psoriatic and enteropathic arthropathies
0.900 0.100 0.000
E11.9 Without complications
0.899 0.101 0.000
G62 Other polyneuropathies
0.899 0.101 0.000
I60-I69 Cerebrovascular diseases
0.897 0.103 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.895 0.105 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.893 0.107 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.892 0.108 0.000
M13.9 Arthritis, unspecified
0.890 0.110 0.000
S80-S89 Injuries to the knee and lower leg
0.889 0.111 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.887 0.113 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.887 0.113 0.000
F10.2 Dependence syndrome
0.885 0.115 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.884 0.116 0.000
H40-H42 Glaucoma
0.883 0.117 0.000
L89 Decubitus ulcer
0.879 0.121 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.878 0.122 0.000
S60-S69 Injuries to the wrist and hand
0.876 0.124 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.874 0.126 0.000
F10.3 Withdrawal state
0.874 0.126 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.868 0.132 0.000
L40-L45 Papulosquamous disorders
0.868 0.132 0.000
L81 Other disorders of pigmentation
0.868 0.132 0.000
G90-G99 Other disorders of the nervous system
0.866 0.134 0.000
E50-E64 Other nutritional deficiencies
0.864 0.136 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.860 0.140 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.859 0.141 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.854 0.146 0.000
Z73 Problems related to life-management difficulty
0.854 0.146 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.852 0.148 0.000
M07.3 Other psoriatic arthropathies
0.851 0.149 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.850 0.150 0.000
M40-M43 Deforming dorsopathies
0.850 0.150 0.000
Chapter X Diseases of the respiratory system
0.845 0.155 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.841 0.159 0.000
S40-S49 Injuries to the shoulder and upper arm
0.838 0.162 0.000
G62.9 Polyneuropathy, unspecified
0.837 0.163 0.000
G40-G47 Episodic and paroxysmal disorders
0.836 0.164 0.000
H53-H54 Visual disturbances and blindness
0.833 0.167 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.832 0.168 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.831 0.169 0.000
F32 Depressive episode
0.830 0.170 0.000
E20-E35 Disorders of other endocrine glands
0.827 0.173 0.000
T86 Failure and rejection of transplanted organs and tissues
0.825 0.175 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.824 0.176 0.000
S00-S09 Injuries to the head
0.822 0.178 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.817 0.183 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.817 0.183 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.816 0.184 0.000
H40 Glaucoma
0.816 0.184 0.000
I20-I25 Ischaemic heart diseases
0.813 0.187 0.000
E00-E07 Disorders of thyroid gland
0.813 0.187 0.000
E83 Disorders of mineral metabolism
0.812 0.188 0.000
E11.4 With neurological complications
0.811 0.189 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.810 0.190 0.000
F03 Unspecified dementia
0.802 0.198 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.802 0.198 0.000
G61 Inflammatory polyneuropathy
0.800 0.200 0.000
E11.2 With renal complications
0.798 0.202 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.797 0.203 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.797 0.203 0.000
E11.3 With ophthalmic complications
0.796 0.204 0.000
H10-H13 Disorders of conjunctiva
0.795 0.205 0.000
F10.4 Withdrawal state with delirium
0.795 0.205 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.795 0.205 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.793 0.207 0.000
L81.4 Other melanin hyperpigmentation
0.792 0.208 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.792 0.208 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.792 0.208 0.000
Y86 Sequelae of other accidents
0.792 0.208 0.000
T79-T79 Certain early complications of trauma
0.791 0.209 0.000
W00-W19 Falls
0.790 0.209 0.000
J09-J18 Influenza and pneumonia
0.789 0.211 0.000
I30-I52 Other forms of heart disease
0.789 0.211 0.000
H40.9 Glaucoma, unspecified
0.789 0.211 0.000
Chapter I Certain infectious and parasitic diseases
0.789 0.211 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.788 0.212 0.000
M80-M85 Disorders of bone density and structure
0.787 0.213 0.000
L40 Psoriasis
0.787 0.213 0.000
S90-S99 Injuries to the ankle and foot
0.786 0.214 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.785 0.215 0.000
I20 Angina pectoris
0.783 0.217 0.000
S61 Open wound of wrist and hand
0.782 0.218 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.781 0.219 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.781 0.219 0.000
M13.98 Arthritis, unspecified (Other)
0.780 0.220 0.000
L91 Hypertrophic disorders of skin
0.780 0.220 0.000
Chapter XXII Codes for special purposes
0.775 0.225 0.000
T51 Toxic effect of alcohol
0.773 0.226 0.000
T81.9 Unspecified complication of procedure
0.772 0.228 0.000
G30-G32 Other degenerative diseases of the nervous system
0.772 0.228 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.772 0.228 0.000
I61 Intracerebral haemorrhage
0.772 0.228 0.000
Z71.1 Person with feared complaint in whom no diagnosis is made
0.771 0.229 0.000
I67 Other cerebrovascular diseases
0.770 0.230 0.000
M14 Arthropathies in other diseases classified elsewhere
0.769 0.231 0.000
Z73.9 Problem related to life-management difficulty, unspecified
0.768 0.232 0.000
E85 Amyloidosis
0.766 0.234 0.000
F10.0 Acute intoxication
0.764 0.236 0.000
L89.9 Decubitus ulcer and pressure area, unspecified
0.764 0.236 0.000
H18 Other disorders of cornea
0.763 0.237 0.000
E83.4 Disorders of magnesium metabolism
0.758 0.242 0.000
Chapter VIII Diseases of the ear and mastoid process
0.758 0.242 0.000
I20.0 Unstable angina
0.758 0.242 0.000
Z72.2 Drug use
0.757 0.243 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.756 0.244 0.000
S86 Injury of muscle and tendon at lower leg level
0.754 0.245 0.000
S50-S59 Injuries to the elbow and forearm
0.754 0.246 0.000
S70-S79 Injuries to the hip and thigh
0.753 0.246 0.000
E10 Insulin-dependent diabetes mellitus
0.753 0.247 0.000
I05-I09 Chronic rheumatic heart diseases
0.753 0.247 0.000
G47 Sleep disorders
0.751 0.249 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.750 0.250 0.000
F10.1 Harmful use
0.750 0.250 0.000
S20-S29 Injuries to the thorax
0.748 0.252 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.748 0.252 0.000
E16 Other disorders of pancreatic internal secretion
0.747 0.253 0.000
M06 Other rheumatoid arthritis
0.746 0.254 0.000
M41 Scoliosis
0.746 0.254 0.000
J18 Pneumonia, organism unspecified
0.744 0.256 0.000
L84 Corns and callosities
0.743 0.257 0.000
H30-H36 Disorders of choroid and retina
0.743 0.257 0.000
M50-M54 Other dorsopathies
0.743 0.257 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.742 0.258 0.000
J30-J39 Other diseases of upper respiratory tract
0.739 0.261 0.000
G20-G26 Extrapyramidal and movement disorders
0.738 0.262 0.000
L85 Other epidermal thickening
0.738 0.262 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.735 0.265 0.000
H53 Visual disturbances
0.735 0.265 0.000
W20-W49 Exposure to inanimate mechanical forces
0.733 0.267 0.000
M86-M90 Other osteopathies
0.732 0.268 0.000
I69 Sequelae of cerebrovascular disease
0.732 0.268 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.732 0.268 0.000
L89.3 Stage IV decubitus ulcer
0.732 0.268 0.000
H55-H59 Other disorders of eye and adnexa
0.731 0.269 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.731 0.269 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.730 0.270 0.000
T66-T78 Other and unspecified effects of external causes
0.727 0.273 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.725 0.275 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.725 0.275 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.724 0.276 0.000
E87.0 Hyperosmolality and hypernatraemia
0.723 0.277 0.000
F80-F89 Disorders of psychological development
0.723 0.277 0.000
M65-M68 Disorders of synovium and tendon
0.722 0.278 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.721 0.279 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.721 0.279 0.000
M11 Other crystal arthropathies
0.720 0.280 0.000
F31 Bipolar affective disorder
0.719 0.281 0.000
F32.9 Depressive episode, unspecified
0.717 0.283 0.000
S81 Open wound of lower leg
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
E40-E46 Malnutrition
0.717 0.283 0.000
O80-O84 Delivery
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.284 0.000
F70-F79 Mental retardation
0.716 0.284 0.000
F60-F69 Disorders of adult personality and behaviour
0.716 0.284 0.000
G70-G73 Diseases of myoneural junction and muscle
0.716 0.284 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.716 0.284 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.716 0.284 0.000
E13 Other specified diabetes mellitus
0.715 0.285 0.000
E12 Malnutrition-related diabetes mellitus
0.715 0.285 0.000
J18.1 Lobar pneumonia, unspecified
0.715 0.285 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.714 0.286 0.000
E04 Other non-toxic goitre
0.714 0.286 0.000
G62.8 Other specified polyneuropathies
0.711 0.289 0.000
E53 Deficiency of other B group vitamins
0.710 0.290 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.710 0.290 0.000
Q60-Q64 Congenital malformations of the urinary system
0.708 0.292 0.000
L10-L14 Bullous disorders
0.708 0.292 0.000
G47.3 Sleep apnoea
0.707 0.293 0.000
T87 Complications peculiar to reattachment and amputation
0.707 0.293 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.707 0.293 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.707 0.293 0.000
Z74 Problems related to care-provider dependency
0.707 0.293 0.000
Z71.6 Tobacco abuse counselling
0.706 0.294 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.706 0.294 0.000
T51.0 Ethanol
0.706 0.294 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.706 0.294 0.000
O16 Unspecified maternal hypertension
0.705 0.295 0.000
I47 Paroxysmal tachycardia
0.703 0.297 0.000
S32 Fracture of lumbar spine and pelvis
0.703 0.297 0.000
S42 Fracture of shoulder and upper arm
0.703 0.297 0.000
M91-M94 Chondropathies
0.702 0.297 0.000
M60-M63 Disorders of muscles
0.702 0.297 0.000
M00-M03 Infectious arthropathies
0.702 0.297 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.702 0.298 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.702 0.298 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.702 0.298 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.702 0.298 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.702 0.298 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.702 0.298 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.702 0.298 0.000
F11 Mental and behavioural disorders due to use of opioids
0.702 0.298 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.701 0.299 0.000
F99-F99 Unspecified mental disorder
0.699 0.300 0.000
E14.8 With unspecified complications
0.699 0.301 0.000
E14.7 With multiple complications
0.699 0.301 0.000
E14.6 With other specified complications
0.699 0.301 0.000
E14.5 With peripheral circulatory complications
0.699 0.301 0.000
E14.4 With neurological complications
0.699 0.301 0.000
E14.3 With ophthalmic complications
0.699 0.301 0.000
E14.2 Withrenal complications
0.699 0.301 0.000
E14.1 With ketoacidosis
0.699 0.301 0.000
E14.0 With coma
0.699 0.301 0.000
S80 Superficial injury of lower leg
0.698 0.302 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.698 0.302 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.698 0.302 0.000
L94 Other localised connective tissue disorders
0.698 0.302 0.000
L93 Lupus erythematosus
0.698 0.302 0.000
L87 Transepidermal elimination disorders
0.698 0.302 0.000
L88 Pyoderma gangrenosum
0.698 0.302 0.000
L86 Keratoderma in diseases classified elsewhere
0.698 0.302 0.000
L83 Acanthosis nigricans
0.698 0.302 0.000
L80 Vitiligo
0.698 0.302 0.000
E87.6 Hypokalaemia
0.698 0.302 0.000
E11.8 With unspecified complications
0.697 0.303 0.000
E11.7 With multiple complications
0.697 0.303 0.000
E11.6 With other specified complications
0.697 0.303 0.000
E11.1 With ketoacidosis
0.697 0.303 0.000
E11.0 With coma
0.697 0.303 0.000
G40 Epilepsy
0.696 0.304 0.000
H21 Other disorders of iris and ciliary body
0.695 0.304 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.695 0.305 0.000
M12 Other specific arthropathies
0.695 0.305 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.695 0.305 0.000
M08 Juvenile arthritis
0.695 0.305 0.000
L82 Seborrhoeic keratosis
0.695 0.305 0.000
J60-J70 Lung diseases due to external agents
0.694 0.306 0.000
F10.9 Unspecified mental and behavioural disorder
0.692 0.308 0.000
F10.8 Other mental and behavioural disorders
0.692 0.308 0.000
F10.7 Residual and late-onset psychotic disorder
0.692 0.308 0.000
F10.6 Amnesic syndrome
0.692 0.308 0.000
F10.5 Psychotic disorder
0.692 0.308 0.000
H53.2 Diplopia
0.692 0.308 0.000
S00 Superficial injury of head
0.692 0.308 0.000
L40.5 Arthropathic psoriasis
0.692 0.308 0.000
I44 Atrioventricular and left bundle-branch block
0.692 0.308 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.691 0.309 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.691 0.309 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.691 0.309 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.691 0.309 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.691 0.309 0.000
G60 Hereditary and idiopathic neuropathy
0.690 0.310 0.000
G64 Other disorders of peripheral nervous system
0.690 0.310 0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis
0.690 0.310 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.690 0.310 0.000
B95-B98 Bacterial, viral and other infectious agents
0.689 0.311 0.000
E11.5 With peripheral circulatory complications
0.689 0.311 0.000
Z76 Persons encountering health services in other circumstances
0.689 0.311 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.689 0.311 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.688 0.312 0.000
G35 Multiple sclerosis
0.687 0.313 0.000
E55 Vitamin D deficiency
0.687 0.313 0.000
Z72.9 Problem related to lifestyle, unspecified
0.686 0.314 0.000
Z72.8 Other problems related to lifestyle
0.686 0.314 0.000
Z72.6 Gambling and betting
0.686 0.314 0.000
Z72.5 High-risk sexual behaviour
0.686 0.314 0.000
Z72.4 Inappropriate diet and eating habits
0.686 0.314 0.000
Z72.3 Lack of physical exercise
0.686 0.314 0.000
E87.2 Acidosis
0.685 0.314 0.000
Y35-Y36 Legal intervention and operations of war
0.685 0.315 0.000
Y10-Y34 Event of undetermined intent
0.685 0.315 0.000
Y00-Y09 Assault
0.685 0.315 0.000
X85-X99 Assault
0.685 0.315 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.685 0.315 0.000
X50-X57 Overexertion, travel and privation
0.685 0.315 0.000
X30-X39 Exposure to forces of nature
0.685 0.315 0.000
X20-X29 Contact with venomous animals and plants
0.685 0.315 0.000
X10-X19 Contact with heat and hot substances
0.685 0.315 0.000
X00-X09 Exposure to smoke, fire and flames
0.685 0.315 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.685 0.315 0.000
W75-W84 Other accidental threats to breathing
0.685 0.315 0.000
W65-W74 Accidental drowning and submersion
0.685 0.315 0.000
W50-W64 Exposure to animate mechanical forces
0.685 0.315 0.000
V98-V99 Other and unspecified transport accidents
0.685 0.315 0.000
V95-V97 Air and space transport accidents
0.685 0.315 0.000
V90-V94 Water transport accidents
0.685 0.315 0.000
V80-V89 Other land transport accidents
0.685 0.315 0.000
V70-V79 Bus occupant injured in transport accident
0.685 0.315 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.685 0.315 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.685 0.315 0.000
V40-V49 Car occupant injured in transport accident
0.685 0.315 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.685 0.315 0.000
V01-V09 Pedestrian injured in transport accident
0.685 0.315 0.000
E88 Other metabolic disorders
0.685 0.315 0.000
E84 Cystic fibrosis
0.685 0.315 0.000
E79 Disorders of purine and pyrimidine metabolism
0.685 0.315 0.000
E77 Disorders of glycoprotein metabolism
0.685 0.315 0.000
E76 Disorders of glycosaminoglycan metabolism
0.685 0.315 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.685 0.315 0.000
E74 Other disorders of carbohydrate metabolism
0.685 0.315 0.000
E73 Lactose intolerance
0.685 0.315 0.000
E72 Other disorders of amino-acid metabolism
0.685 0.315 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.685 0.315 0.000
E70 Disorders of aromatic amino-acid metabolism
0.685 0.315 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.685 0.315 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.684 0.316 0.000
G61.0 Guillain-Barre syndrome
0.684 0.316 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.683 0.317 0.000
E07 Other disorders of thyroid
0.683 0.317 0.000
E78.5 Hyperlipidaemia, unspecified
0.681 0.319 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.681 0.319 0.000
E87.5 Hyperkalaemia
0.680 0.320 0.000
S60 Superficial injury of wrist and hand
0.679 0.321 0.000
G93 Other disorders of brain
0.679 0.321 0.000
M13.0 Polyarthritis, unspecified
0.678 0.322 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.678 0.322 0.000
S61.0 Open wound of finger(s) without damage to nail
0.677 0.323 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.675 0.325 0.000
Z71.3 Dietary counselling and surveillance
0.675 0.325 0.000
Y95 Nosocomial condition
0.675 0.325 0.000
G81 Hemiplegia
0.674 0.326 0.000
F01 Vascular dementia
0.674 0.326 0.000
I24 Other acute ischaemic heart diseases
0.673 0.327 0.000
M20-M25 Other joint disorders
0.673 0.327 0.000
M41.9 Scoliosis, unspecified
0.672 0.328 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.672 0.328 0.000
S67 Crushing injury of wrist and hand
0.672 0.328 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.671 0.329 0.000
E16.2 Hypoglycaemia, unspecified
0.671 0.329 0.000
L50-L54 Urticaria and erythema
0.671 0.329 0.000
L90 Atrophic disorders of skin
0.671 0.329 0.000
I00-I02 Acute rheumatic fever
0.671 0.329 0.000
J35 Chronic diseases of tonsils and adenoids
0.670 0.330 0.000
T86.1 Kidney transplant failure and rejection
0.670 0.330 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.670 0.330 0.000
G95 Other diseases of spinal cord
0.669 0.331 0.000
V20-V29 Motorcycle rider injured in transport accident
0.668 0.332 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.668 0.332 0.000
I45 Other conduction disorders
0.668 0.332 0.000
H20 Iridocyclitis
0.667 0.333 0.000
E65-E68 Obesity and other hyperalimentation
0.666 0.334 0.000
I67.8 Other specified cerebrovascular diseases
0.665 0.335 0.000
H43-H45 Disorders of vitreous body and globe
0.665 0.335 0.000
H90-H95 Other disorders of ear
0.664 0.336 0.000
Z71.9 Counselling, unspecified
0.664 0.336 0.000
M13.8 Other specified arthritis
0.662 0.338 0.000
M13.1 Monoarthritis, not elsewhere classified
0.662 0.338 0.000
M05 Seropositive rheumatoid arthritis
0.662 0.338 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.661 0.339 0.000
B35-B49 Mycoses
0.661 0.339 0.000
F25 Schizoaffective disorders
0.659 0.340 0.000
H25-H28 Disorders of lens
0.659 0.341 0.000
E27 Other disorders of adrenal gland
0.659 0.341 0.000
S86.8 Injury of other muscles and tendons at lower leg level
0.658 0.342 0.000
L91.8 Other hypertrophic disorders of skin
0.658 0.342 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.655 0.345 0.000
S69 Other and unspecified injuries of wrist and hand
0.655 0.345 0.000
F32.1 Moderate depressive episode
0.652 0.348 0.000
T86.8 Failure and rejection of other transplanted organs and tissues
0.652 0.348 0.000
F38 Other mood [affective] disorders
0.652 0.348 0.000
F34 Persistent mood [affective] disorders
0.652 0.348 0.000
F30 Manic episode
0.652 0.348 0.000
F39 Unspecified mood [affective] disorder
0.652 0.348 0.000
Q00-Q07 Congenital malformations of the nervous system
0.651 0.349 0.000
V10-V19 Pedal cyclist injured in transport accident
0.651 0.349 0.000
H18.5 Hereditary corneal dystrophies
0.651 0.349 0.000
E61 Deficiency of other nutrient elements
0.651 0.349 0.000
G82 Paraplegia and tetraplegia
0.651 0.349 0.000
G63.2 Diabetic polyneuropathy
0.651 0.349 0.000
G50 Disorders of trigeminal nerve
0.650 0.350 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.649 0.351 0.000
M10 Gout
0.646 0.353 0.000
S06 Intracranial injury
0.646 0.353 0.000
F12.1 Harmful use
0.646 0.354 0.000
M07.6 Other enteropathic arthropathies
0.645 0.354 0.000
M07.5 Arthropathy in ulcerative colitis
0.645 0.354 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.645 0.354 0.000
M07.2 Psoriatic spondylitis
0.645 0.354 0.000
M07.1 Arthritis mutilans
0.645 0.354 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.645 0.354 0.000
G62.2 Polyneuropathy due to other toxic agents
0.644 0.356 0.000
G62.1 Alcoholic polyneuropathy
0.644 0.356 0.000
G62.0 Drug-induced polyneuropathy
0.644 0.356 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.643 0.357 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.643 0.357 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.643 0.357 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.643 0.357 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.642 0.358 0.000
X60-X84 Intentional self-harm
0.642 0.358 0.000
Z75 Problems related to medical facilities and other health care
0.642 0.358 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.642 0.358 0.000
F02 Dementia in other diseases classified elsewhere
0.642 0.358 0.000
F00 Dementia in Alzheimer's disease
0.642 0.358 0.000
F09 Unspecified organic or symptomatic mental disorder
0.642 0.358 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.642 0.358 0.000
L03 Cellulitis
0.641 0.359 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.641 0.359 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.641 0.359 0.000
L05 Pilonidal cyst
0.641 0.359 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.640 0.360 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.640 0.360 0.000
E87.4 Mixed disorder of acid-base balance
0.640 0.360 0.000
E87.3 Alkalosis
0.640 0.360 0.000
E23 Hypofunction and other disorders of pituitary gland
0.640 0.360 0.000
Z73.3 Stress, not elsewhere classified
0.639 0.360 0.000
S82 Fracture of lower leg, including ankle
0.639 0.361 0.000
M13.93 Arthritis, unspecified (Forearm)
0.638 0.362 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.638 0.362 0.000
S89 Other and unspecified injuries of lower leg
0.637 0.363 0.000
S88 Traumatic amputation of lower leg
0.637 0.363 0.000
S87 Crushing injury of lower leg
0.637 0.363 0.000
S85 Injury of blood vessels at lower leg level
0.637 0.363 0.000
S84 Injury of nerves at lower leg level
0.637 0.363 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.637 0.363 0.000
G37 Other demyelinating diseases of central nervous system
0.637 0.363 0.000
Y88 Sequelae of surgical and medical care as external cause
0.636 0.364 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.636 0.364 0.000
Q80-Q89 Other congenital malformations
0.636 0.364 0.000
Q50-Q56 Congenital malformations of genital organs
0.636 0.364 0.000
Q35-Q37 Cleft lip and cleft palate
0.636 0.364 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.636 0.364 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.636 0.364 0.000
M13.94 Arthritis, unspecified (Hand)
0.636 0.364 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.636 0.364 0.000
S37 Injury of urinary and pelvic organs
0.636 0.364 0.000
S36 Injury of intra-abdominal organs
0.636 0.364 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.636 0.364 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.636 0.364 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.636 0.364 0.000
S31 Open wound of abdomen, lower back and pelvis
0.636 0.364 0.000
G58 Other mononeuropathies
0.635 0.365 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.634 0.366 0.000
L40.9 Psoriasis, unspecified
0.634 0.366 0.000
H42 Glaucoma in diseases classified elsewhere
0.633 0.366 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.633 0.367 0.000
M43 Other deforming dorsopathies
0.633 0.367 0.000
O60-O75 Complications of labour and delivery
0.633 0.367 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.632 0.368 0.000
I60 Subarachnoid haemorrhage
0.632 0.368 0.000
E85.9 Amyloidosis, unspecified
0.631 0.369 0.000
S90 Superficial injury of ankle and foot
0.631 0.369 0.000
F33 Recurrent depressive disorder
0.631 0.369 0.000
L89.2 Stage III decubitus ulcer
0.630 0.370 0.000
L89.1 Stage II decubitus ulcer
0.630 0.370 0.000
L89.0 Stage I decubitus ulcer and pressure area
0.630 0.370 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.630 0.370 0.000
I67.9 Cerebrovascular disease, unspecified
0.630 0.370 0.000
G91 Hydrocephalus
0.630 0.370 0.000
S02 Fracture of skull and facial bones
0.630 0.370 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.629 0.371 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.629 0.371 0.000
H17 Corneal scars and opacities
0.629 0.371 0.000
H16 Keratitis
0.629 0.371 0.000
H15 Disorders of sclera
0.629 0.371 0.000
J38.1 Polyp of vocal cord and larynx
0.629 0.371 0.000
E28 Ovarian dysfunction
0.628 0.372 0.000
S68 Traumatic amputation of wrist and hand
0.628 0.372 0.000
S65 Injury of blood vessels at wrist and hand level
0.628 0.372 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.628 0.372 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.627 0.373 0.000
I05 Rheumatic mitral valve diseases
0.627 0.373 0.000
Z71.7 Human immunodeficiency virus [HIV] counselling
0.626 0.373 0.000
Z71.5 Drug abuse counselling and surveillance
0.626 0.373 0.000
Z71.4 Alcohol abuse counselling and surveillance
0.626 0.373 0.000
Z71.2 Person consulting for explanation of investigation findings
0.626 0.373 0.000
Z71.0 Person consulting on behalf of another person
0.626 0.373 0.000
M14.6 Neuropathic arthropathy
0.626 0.374 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.625 0.375 0.000
E83.3 Disorders of phosphorus metabolism
0.625 0.375 0.000
H11 Other disorders of conjunctiva
0.624 0.376 0.000
H10 Conjunctivitis
0.624 0.376 0.000
W19 Unspecified fall
0.624 0.376 0.000
I20.9 Angina pectoris, unspecified
0.624 0.376 0.000
I62 Other nontraumatic intracranial haemorrhage
0.623 0.377 0.000
S40 Superficial injury of shoulder and upper arm
0.623 0.377 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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