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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74859699
log Bayes Factor = 18.3331
Chromosome 1   position 154,739,875  (GRCh37) Explore rs74859699 on Ensembl!
Variant rs74859699 is part of Cluster X0032

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
1.000 0.000 0.000
I30-I52 Other forms of heart disease
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
Chapter VI Diseases of the nervous system
0.998 0.002 0.000
E70-E90 Metabolic disorders
0.998 0.002 0.000
Chapter X Diseases of the respiratory system
0.998 0.002 0.000
Q60-Q64 Congenital malformations of the urinary system
0.995 0.005 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.994 0.006 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.994 0.006 0.000
M70-M79 Other soft tissue disorders
0.992 0.008 0.000
Chapter XX External causes of morbidity and mortality
0.992 0.008 0.000
Q61 Cystic kidney disease
0.992 0.008 0.000
E86 Volume depletion
0.989 0.011 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.989 0.011 0.000
Chapter V Mental and behavioural disorders
0.984 0.016 0.000
E87.5 Hyperkalaemia
0.984 0.016 0.000
I51 Complications and ill-defined descriptions of heart disease
0.983 0.017 0.000
J95-J99 Other diseases of the respiratory system
0.982 0.018 0.000
I05-I09 Chronic rheumatic heart diseases
0.975 0.025 0.000
G40-G47 Episodic and paroxysmal disorders
0.974 0.026 0.000
Q61.3 Polycystic kidney, unspecified
0.972 0.028 0.000
I51.8 Other ill-defined heart diseases
0.968 0.032 0.000
T81 Complications of procedures, not elsewhere classified
0.967 0.033 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.963 0.037 0.000
M79.6 Pain in limb
0.961 0.039 0.000
I20-I25 Ischaemic heart diseases
0.958 0.042 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.954 0.046 0.000
S20-S29 Injuries to the thorax
0.953 0.047 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.943 0.057 0.000
G40 Epilepsy
0.941 0.059 0.000
Q61.2 Polycystic kidney, adult type
0.939 0.061 0.000
J00-J06 Acute upper respiratory infections
0.937 0.063 0.000
I42 Cardiomyopathy
0.932 0.068 0.000
M05-M14 Inflammatory polyarthropathies
0.932 0.068 0.000
G30-G32 Other degenerative diseases of the nervous system
0.931 0.069 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.927 0.073 0.000
I50 Heart failure
0.926 0.074 0.000
Y95 Nosocomial condition
0.924 0.076 0.000
S90-S99 Injuries to the ankle and foot
0.922 0.078 0.000
F30-F39 Mood [affective] disorders
0.921 0.079 0.000
J60-J70 Lung diseases due to external agents
0.920 0.080 0.000
Chapter I Certain infectious and parasitic diseases
0.916 0.084 0.000
I08 Multiple valve diseases
0.916 0.084 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.916 0.084 0.000
J90-J94 Other diseases of pleura
0.913 0.087 0.000
M79.8 Other specified soft tissue disorders
0.913 0.087 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.912 0.088 0.000
B35-B49 Mycoses
0.912 0.088 0.000
M80-M85 Disorders of bone density and structure
0.910 0.090 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.909 0.091 0.000
I21 Acute myocardial infarction
0.908 0.092 0.000
I44 Atrioventricular and left bundle-branch block
0.906 0.094 0.000
B37 Candidiasis
0.905 0.095 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.904 0.096 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.903 0.097 0.000
I34 Nonrheumatic mitral valve disorders
0.899 0.101 0.000
I20 Angina pectoris
0.898 0.102 0.000
S10-S19 Injuries to the neck
0.897 0.103 0.000
Y43 Primarily systemic agents
0.897 0.103 0.000
G43 Migraine
0.897 0.103 0.000
E65-E68 Obesity and other hyperalimentation
0.897 0.103 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.895 0.105 0.000
G90-G99 Other disorders of the nervous system
0.894 0.106 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.893 0.107 0.000
Q00-Q07 Congenital malformations of the nervous system
0.889 0.111 0.000
M79.60 Pain in limb (Multiple sites)
0.889 0.111 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.883 0.117 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.879 0.121 0.000
S80-S89 Injuries to the knee and lower leg
0.878 0.122 0.000
J95.8 Other postprocedural respiratory disorders
0.877 0.123 0.000
J20-J22 Other acute lower respiratory infections
0.876 0.124 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.870 0.130 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.869 0.131 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.869 0.131 0.000
M79.67 Pain in limb (Ankle and foot)
0.868 0.132 0.000
B37.8 Candidiasis of other sites
0.867 0.133 0.000
G40.9 Epilepsy, unspecified
0.867 0.133 0.000
M60-M63 Disorders of muscles
0.866 0.134 0.000
M65-M68 Disorders of synovium and tendon
0.866 0.134 0.000
I20.0 Unstable angina
0.865 0.135 0.000
M20-M25 Other joint disorders
0.864 0.136 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.862 0.138 0.000
S00-S09 Injuries to the head
0.857 0.143 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.855 0.145 0.000
T79-T79 Certain early complications of trauma
0.854 0.146 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.853 0.147 0.000
J69 Pneumonitis due to solids and liquids
0.852 0.148 0.000
Y43.3 Other antineoplastic drugs
0.849 0.151 0.000
J03 Acute tonsillitis
0.848 0.152 0.000
Q61.5 Medullary cystic kidney
0.846 0.154 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.844 0.156 0.000
M06 Other rheumatoid arthritis
0.843 0.157 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.841 0.159 0.000
I21.4 Acute subendocardial myocardial infarction
0.841 0.159 0.000
S90 Superficial injury of ankle and foot
0.841 0.159 0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.839 0.161 0.000
M45-M49 Spondylopathies
0.838 0.162 0.000
J00 Acute nasopharyngitis [common cold]
0.837 0.163 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.837 0.163 0.000
I34.0 Mitral (valve) insufficiency
0.835 0.165 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.834 0.166 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.834 0.166 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.833 0.167 0.000
I71 Aortic aneurysm and dissection
0.832 0.168 0.000
S27 Injury of other and unspecified intrathoracic organs
0.830 0.170 0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified
0.830 0.170 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.829 0.170 0.000
I49 Other cardiac arrhythmias
0.828 0.172 0.000
S20 Superficial injury of thorax
0.827 0.173 0.000
I05 Rheumatic mitral valve diseases
0.824 0.176 0.000
J92 Pleural plaque
0.824 0.176 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.822 0.178 0.000
J99.8 Respiratory disorders in other diseases classified elsewhere
0.822 0.178 0.000
X60-X84 Intentional self-harm
0.820 0.180 0.000
I07 Rheumatic tricuspid valve diseases
0.819 0.181 0.000
G93 Other disorders of brain
0.818 0.182 0.000
M79.2 Neuralgia and neuritis, unspecified
0.815 0.185 0.000
I44.1 Atrioventricular block, second degree
0.815 0.185 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.814 0.186 0.000
G43.9 Migraine, unspecified
0.812 0.188 0.000
E66 Obesity
0.812 0.188 0.000
I44.7 Left bundle-branch block, unspecified
0.811 0.189 0.000
S06 Intracranial injury
0.810 0.190 0.000
I45 Other conduction disorders
0.810 0.190 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.808 0.192 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.808 0.192 0.000
V80-V89 Other land transport accidents
0.807 0.193 0.000
T82.1 Mechanical complication of cardiac electronic device
0.807 0.193 0.000
B37.0 Candidal stomatitis
0.805 0.195 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.804 0.196 0.000
M79.0 Rheumatism, unspecified
0.804 0.196 0.000
J69.0 Pneumonitis due to food and vomit
0.804 0.196 0.000
B49 Unspecified mycosis
0.801 0.199 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.799 0.201 0.000
F32 Depressive episode
0.799 0.201 0.000
M05 Seropositive rheumatoid arthritis
0.798 0.202 0.000
I50.9 Heart failure, unspecified
0.797 0.203 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.797 0.203 0.000
M80 Osteoporosis with pathological fracture
0.797 0.203 0.000
F33 Recurrent depressive disorder
0.796 0.204 0.000
I36 Nonrheumatic tricuspid valve disorders
0.794 0.206 0.000
J22 Unspecified acute lower respiratory infection
0.792 0.208 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.791 0.209 0.000
M91-M94 Chondropathies
0.790 0.210 0.000
S14 Injury of nerves and spinal cord at neck level
0.790 0.210 0.000
M79.69 Pain in limb (Site unspecified)
0.790 0.210 0.000
I20.1 Angina pectoris with documented spasm
0.788 0.212 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.787 0.213 0.000
I42.0 Dilated cardiomyopathy
0.786 0.213 0.000
M79.7 Fibromyalgia
0.786 0.214 0.000
E20-E35 Disorders of other endocrine glands
0.786 0.214 0.000
J03.9 Acute tonsillitis, unspecified
0.785 0.215 0.000
F42 Obsessive-compulsive disorder
0.785 0.215 0.000
E74 Other disorders of carbohydrate metabolism
0.784 0.215 0.000
F05.9 Delirium, unspecified
0.784 0.216 0.000
I31 Other diseases of pericardium
0.783 0.217 0.000
X00-X09 Exposure to smoke, fire and flames
0.781 0.219 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.780 0.220 0.000
E87.6 Hypokalaemia
0.780 0.220 0.000
J01 Acute sinusitis
0.780 0.220 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.779 0.221 0.000
J98 Other respiratory disorders
0.779 0.221 0.000
G41 Status epilepticus
0.778 0.222 0.000
S90.9 Superficial injury of ankle and foot, unspecified
0.777 0.223 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.776 0.224 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.775 0.225 0.000
F60-F69 Disorders of adult personality and behaviour
0.774 0.226 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.773 0.227 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.773 0.227 0.000
Y48 Anaesthetics and therapeutic gases
0.771 0.229 0.000
M47 Spondylosis
0.769 0.231 0.000
M76 Enthesopathies of lower limb, excluding foot
0.768 0.231 0.000
T66-T78 Other and unspecified effects of external causes
0.768 0.232 0.000
I44.3 Other and unspecified atrioventricular block
0.768 0.232 0.000
M79.1 Myalgia
0.767 0.233 0.000
Q05 Spina bifida
0.767 0.233 0.000
G70-G73 Diseases of myoneural junction and muscle
0.766 0.234 0.000
J09-J18 Influenza and pneumonia
0.766 0.234 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.766 0.234 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.765 0.235 0.000
S29 Other and unspecified injuries of thorax
0.763 0.237 0.000
S50-S59 Injuries to the elbow and forearm
0.762 0.238 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.761 0.239 0.000
D75 Other diseases of blood and blood-forming organs
0.761 0.239 0.000
E50-E64 Other nutritional deficiencies
0.761 0.239 0.000
J92.0 Pleural plaque with presence of asbestos
0.760 0.240 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.760 0.240 0.000
Chapter XXII Codes for special purposes
0.760 0.240 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.759 0.241 0.000
I51.7 Cardiomegaly
0.759 0.241 0.000
S82 Fracture of lower leg, including ankle
0.758 0.242 0.000
V40-V49 Car occupant injured in transport accident
0.758 0.242 0.000
I50.0 Congestive heart failure
0.758 0.242 0.000
I50.1 Left ventricular failure
0.758 0.242 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.757 0.243 0.000
I22 Subsequent myocardial infarction
0.756 0.244 0.000
M22 Disorders of patella
0.756 0.244 0.000
E00-E07 Disorders of thyroid gland
0.755 0.245 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.755 0.245 0.000
Q80-Q89 Other congenital malformations
0.753 0.246 0.000
M79.66 Pain in limb (Lower leg)
0.753 0.247 0.000
M62 Other disorders of muscle
0.751 0.249 0.000
D80-D89 Certain disorders involving the immune mechanism
0.751 0.249 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.749 0.250 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.749 0.251 0.000
F80-F89 Disorders of psychological development
0.749 0.251 0.000
M77 Other enthesopathies
0.749 0.251 0.000
G93.3 Postviral fatigue syndrome
0.749 0.251 0.000
M06.9 Rheumatoid arthritis, unspecified
0.748 0.252 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.746 0.254 0.000
B37.4 Candidiasis of other urogenital sites
0.745 0.255 0.000
B44 Aspergillosis
0.744 0.256 0.000
T90 Sequelae of injuries of head
0.744 0.256 0.000
S27.0 Traumatic pneumothorax
0.744 0.256 0.000
I51.4 Myocarditis, unspecified
0.744 0.256 0.000
M65 Synovitis and tenosynovitis
0.743 0.257 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.743 0.257 0.000
E87.0 Hyperosmolality and hypernatraemia
0.742 0.258 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.741 0.258 0.000
R47-R49 Symptoms and signs involving speech and voice
0.740 0.260 0.000
X50-X57 Overexertion, travel and privation
0.740 0.260 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.740 0.260 0.000
Y00-Y09 Assault
0.738 0.262 0.000
E66.9 Obesity, unspecified
0.737 0.263 0.000
M79.64 Pain in limb (Hand)
0.736 0.264 0.000
G00 Bacterial meningitis, not elsewhere classified
0.735 0.265 0.000
I42.6 Alcoholic cardiomyopathy
0.735 0.265 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.734 0.266 0.000
B37.3 Candidiasis of vulva and vagina
0.734 0.266 0.000
S10 Superficial injury of neck
0.734 0.266 0.000
I08.0 Disorders of both mitral and aortic valves
0.734 0.266 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.733 0.267 0.000
M47.8 Other spondylosis
0.733 0.267 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.733 0.267 0.000
G44 Other headache syndromes
0.731 0.269 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.731 0.269 0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis
0.731 0.269 0.000
I21.9 Acute myocardial infarction, unspecified
0.731 0.269 0.000
E87.7 Fluid overload
0.731 0.269 0.000
I42.9 Cardiomyopathy, unspecified
0.730 0.270 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.730 0.270 0.000
F39 Unspecified mood [affective] disorder
0.730 0.270 0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection
0.730 0.270 0.000
D72 Other disorders of white blood cells
0.730 0.270 0.000
I49.3 Ventricular premature depolarisation
0.729 0.271 0.000
J99.0 Rheumatoid lung disease
0.729 0.271 0.000
R27 Other lack of coordination
0.728 0.272 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.728 0.272 0.000
M85 Other disorders of bone density and structure
0.728 0.272 0.000
Q03 Congenital hydrocephalus
0.727 0.272 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.727 0.273 0.000
S20.2 Contusion of thorax
0.727 0.273 0.000
W50-W64 Exposure to animate mechanical forces
0.726 0.274 0.000
M25 Other joint disorders, not elsewhere classified
0.726 0.274 0.000
M33 Dermatopolymyositis
0.725 0.275 0.000
M79.61 Pain in limb (Shoulder region)
0.724 0.276 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.724 0.276 0.000
Y52 Agents primarily affecting the cardiovascular system
0.724 0.276 0.000
M71 Other bursopathies
0.723 0.277 0.000
I30 Acute pericarditis
0.723 0.277 0.000
I45.8 Other specified conduction disorders
0.723 0.277 0.000
X20-X29 Contact with venomous animals and plants
0.722 0.277 0.000
Y40 Systemic antibiotics
0.722 0.278 0.000
F43 Reaction to severe stress, and adjustment disorders
0.722 0.278 0.000
M82 Osteoporosis in diseases classified elsewhere
0.722 0.278 0.000
F45 Somatoform disorders
0.721 0.279 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.721 0.279 0.000
J95.0 Tracheostomy malfunction
0.720 0.280 0.000
I42.2 Other hypertrophic cardiomyopathy
0.719 0.281 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.719 0.281 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.719 0.281 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.719 0.281 0.000
Q50-Q56 Congenital malformations of genital organs
0.717 0.282 0.000
Q76 Congenital malformations of spine and bony thorax
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.717 0.283 0.000
Q35-Q37 Cleft lip and cleft palate
0.717 0.283 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.283 0.000
I48 Atrial fibrillation and flutter
0.716 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.283 0.000
I40 Acute myocarditis
0.716 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.283 0.000
S99 Other and unspecified injuries of ankle and foot
0.716 0.284 0.000
E85 Amyloidosis
0.716 0.284 0.000
E84 Cystic fibrosis
0.716 0.284 0.000
E79 Disorders of purine and pyrimidine metabolism
0.716 0.284 0.000
E77 Disorders of glycoprotein metabolism
0.716 0.284 0.000
E76 Disorders of glycosaminoglycan metabolism
0.716 0.284 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.716 0.284 0.000
E72 Other disorders of amino-acid metabolism
0.716 0.284 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.716 0.284 0.000
E70 Disorders of aromatic amino-acid metabolism
0.716 0.284 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.716 0.284 0.000
M21 Other acquired deformities of limbs
0.714 0.286 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.714 0.286 0.000
Q64 Other congenital malformations of urinary system
0.713 0.286 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.713 0.286 0.000
E87.4 Mixed disorder of acid-base balance
0.713 0.287 0.000
F34 Persistent mood [affective] disorders
0.713 0.287 0.000
M86-M90 Other osteopathies
0.713 0.287 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.713 0.287 0.000
T87 Complications peculiar to reattachment and amputation
0.713 0.287 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.712 0.287 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.712 0.288 0.000
M47.82 Other spondylosis (Cervical region)
0.712 0.288 0.000
Q66 Congenital deformities of feet
0.712 0.288 0.000
G31.8 Other specified degenerative diseases of nervous system
0.711 0.289 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.711 0.289 0.000
Y35-Y36 Legal intervention and operations of war
0.711 0.289 0.000
Y10-Y34 Event of undetermined intent
0.711 0.289 0.000
X85-X99 Assault
0.711 0.289 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.711 0.289 0.000
X30-X39 Exposure to forces of nature
0.711 0.289 0.000
X10-X19 Contact with heat and hot substances
0.711 0.289 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.711 0.289 0.000
W75-W84 Other accidental threats to breathing
0.711 0.289 0.000
W65-W74 Accidental drowning and submersion
0.711 0.289 0.000
V98-V99 Other and unspecified transport accidents
0.711 0.289 0.000
V95-V97 Air and space transport accidents
0.711 0.289 0.000
V90-V94 Water transport accidents
0.711 0.289 0.000
V70-V79 Bus occupant injured in transport accident
0.711 0.289 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.711 0.289 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.711 0.289 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.711 0.289 0.000
V01-V09 Pedestrian injured in transport accident
0.711 0.289 0.000
Q61.9 Cystic kidney disease, unspecified
0.711 0.289 0.000
Q61.8 Other cystic kidney diseases
0.711 0.289 0.000
Q61.4 Renal dysplasia
0.711 0.289 0.000
Q61.1 Polycystic kidney, infantile type
0.711 0.289 0.000
I74 Arterial embolism and thrombosis
0.711 0.289 0.000
G43.1 Migraine with aura [classical migraine]
0.711 0.289 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.710 0.290 0.000
M79.9 Soft tissue disorder, unspecified
0.709 0.291 0.000
M79.3 Panniculitis, unspecified
0.709 0.291 0.000
E87.2 Acidosis
0.709 0.291 0.000
Q63 Other congenital malformations of kidney
0.709 0.291 0.000
J93 Pneumothorax
0.709 0.291 0.000
I70 Atherosclerosis
0.708 0.292 0.000
G40.5 Special epileptic syndromes
0.708 0.292 0.000
I07.1 Tricuspid insufficiency
0.708 0.292 0.000
I37 Pulmonary valve disorders
0.707 0.293 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.706 0.294 0.000
I51.6 Cardiovascular disease, unspecified
0.706 0.294 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.706 0.294 0.000
F70-F79 Mental retardation
0.706 0.294 0.000
E73 Lactose intolerance
0.705 0.295 0.000
I51.5 Myocardial degeneration
0.705 0.295 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.705 0.295 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.705 0.295 0.000
I51.0 Cardiac septal defect, acquired
0.705 0.295 0.000
E87.3 Alkalosis
0.704 0.296 0.000
R44.0 Auditory hallucinations
0.704 0.296 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.704 0.296 0.000
J96 Respiratory failure, not elsewhere classified
0.704 0.296 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.702 0.298 0.000
R47 Speech disturbances, not elsewhere classified
0.702 0.298 0.000
G93.4 Encephalopathy, unspecified
0.701 0.299 0.000
S50 Superficial injury of forearm
0.701 0.299 0.000
V20-V29 Motorcycle rider injured in transport accident
0.700 0.300 0.000
J91 Pleural effusion in conditions classified elsewhere
0.700 0.300 0.000
M07 Psoriatic and enteropathic arthropathies
0.700 0.300 0.000
J94 Other pleural conditions
0.700 0.300 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.699 0.301 0.000
F33.9 Recurrent depressive disorder, unspecified
0.699 0.301 0.000
S00 Superficial injury of head
0.699 0.301 0.000
I09 Other rheumatic heart diseases
0.699 0.301 0.000
I06 Rheumatic aortic valve diseases
0.699 0.301 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.698 0.302 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.696 0.304 0.000
S05 Injury of eye and orbit
0.696 0.304 0.000
M35 Other systemic involvement of connective tissue
0.695 0.305 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.694 0.306 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.694 0.306 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.694 0.306 0.000
Y43.1 Antineoplastic antimetabolites
0.693 0.307 0.000
Y43.0 Antiallergic and antiemetic drugs
0.691 0.309 0.000
S83.2 Tear of meniscus, current
0.691 0.309 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.691 0.309 0.000
G03 Meningitis due to other and unspecified causes
0.691 0.309 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.691 0.309 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.691 0.309 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.691 0.309 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.691 0.309 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.690 0.310 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.690 0.310 0.000
R47.8 Other and unspecified speech disturbances
0.689 0.311 0.000
S70-S79 Injuries to the hip and thigh
0.689 0.311 0.000
M79.68 Pain in limb (Other)
0.689 0.311 0.000
M40-M43 Deforming dorsopathies
0.688 0.311 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.688 0.312 0.000
E28 Ovarian dysfunction
0.687 0.313 0.000
I23 Certain current complications following acute myocardial infarction
0.687 0.313 0.000
T80.2 Infections following infusion, transfusion and therapeutic injection
0.686 0.314 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.685 0.314 0.000
M00-M03 Infectious arthropathies
0.685 0.315 0.000
E07 Other disorders of thyroid
0.685 0.315 0.000
M06.0 Seronegative rheumatoid arthritis
0.685 0.315 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.684 0.316 0.000
Y98 Lifestyle-related condition
0.684 0.316 0.000
Y97 Environmental-pollution-related condition
0.684 0.316 0.000
Y96 Work-related condition
0.684 0.316 0.000
D75.1 Secondary polycythaemia
0.684 0.316 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.684 0.316 0.000
S26 Injury of heart
0.684 0.316 0.000
S25 Injury of blood vessels of thorax
0.684 0.316 0.000
S24 Injury of nerves and spinal cord at thorax level
0.684 0.316 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.684 0.316 0.000
S21 Open wound of thorax
0.684 0.316 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.683 0.317 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.683 0.317 0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)
0.682 0.318 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.681 0.319 0.000
G96 Other disorders of central nervous system
0.681 0.319 0.000
E65 Localised adiposity
0.680 0.320 0.000
R42 Dizziness and giddiness
0.679 0.321 0.000
Q05.9 Spina bifida, unspecified
0.679 0.321 0.000
M79.5 Residual foreign body in soft tissue
0.678 0.322 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.678 0.322 0.000
M22.2 Patellofemoral disorders
0.678 0.322 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.678 0.322 0.000
M13 Other arthritis
0.677 0.323 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.677 0.323 0.000
A30-A49 Other bacterial diseases
0.677 0.323 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.677 0.323 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.676 0.324 0.000
G93.6 Cerebral oedema
0.676 0.324 0.000
Y59 Other and unspecified vaccines and biological substances
0.676 0.324 0.000
Y58 Bacterial vaccines
0.676 0.324 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.676 0.324 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.676 0.324 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.676 0.324 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.676 0.324 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.676 0.324 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.676 0.324 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.676 0.324 0.000
F00 Dementia in Alzheimer's disease
0.675 0.325 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.675 0.325 0.000
X78 Intentional self-harm by sharp object
0.675 0.325 0.000
G40.8 Other epilepsy
0.675 0.325 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.675 0.325 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.675 0.325 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.675 0.325 0.000
M79.63 Pain in limb (Forearm)
0.674 0.325 0.000
G43.8 Other migraine
0.673 0.326 0.000
S14.1 Other and unspecified injuries of cervical spinal cord
0.672 0.328 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.672 0.328 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.671 0.328 0.000
D86 Sarcoidosis
0.671 0.328 0.000
J21 Acute bronchiolitis
0.671 0.329 0.000
F99-F99 Unspecified mental disorder
0.671 0.329 0.000
F40 Phobic anxiety disorders
0.671 0.329 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.670 0.330 0.000
D72.8 Other specified disorders of white blood cells
0.670 0.330 0.000
M62.8 Other specified disorders of muscle
0.670 0.330 0.000
M72 Fibroblastic disorders
0.669 0.331 0.000
I42.8 Other cardiomyopathies
0.668 0.332 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.668 0.332 0.000
I42.5 Other restrictive cardiomyopathy
0.668 0.332 0.000
I42.4 Endocardial fibroelastosis
0.668 0.332 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.668 0.332 0.000
M14 Arthropathies in other diseases classified elsewhere
0.668 0.332 0.000
M12 Other specific arthropathies
0.668 0.332 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.668 0.332 0.000
M08 Juvenile arthritis
0.668 0.332 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.667 0.333 0.000
J01.9 Acute sinusitis, unspecified
0.667 0.333 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.665 0.334 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.665 0.335 0.000
E29 Testicular dysfunction
0.665 0.335 0.000
J95.9 Postprocedural respiratory disorder, unspecified
0.664 0.335 0.000
J95.5 Postprocedural subglottic stenosis
0.664 0.335 0.000
J95.4 Mendelson's syndrome
0.664 0.335 0.000
J95.3 Chronic pulmonary insufficiency following surgery
0.664 0.335 0.000
J95.2 Acute pulmonary insufficiency following nonthoracic surgery
0.664 0.335 0.000
J95.1 Acute pulmonary insufficiency following thoracic surgery
0.664 0.335 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.665 0.335 0.000
B99-B99 Other infectious diseases
0.664 0.336 0.000
S89 Other and unspecified injuries of lower leg
0.664 0.336 0.000
W20-W49 Exposure to inanimate mechanical forces
0.663 0.336 0.000
M79.20 Neuralgia and neuritis, unspecified (Multiple sites)
0.663 0.337 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.663 0.337 0.000
F42.0 Predominantly obsessional thoughts or ruminations
0.662 0.338 0.000
G30 Alzheimer's disease
0.662 0.338 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.662 0.338 0.000
S98 Traumatic amputation of ankle and foot
0.661 0.339 0.000
S97 Crushing injury of ankle and foot
0.661 0.339 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.661 0.339 0.000
S95 Injury of blood vessels at ankle and foot level
0.661 0.339 0.000
S94 Injury of nerves at ankle and foot level
0.661 0.339 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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