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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74980942
log Bayes Factor = 19.1141
Chromosome 4   position 129,597,399  (GRCh37) Explore rs74980942 on Ensembl!
Variant rs74980942 is part of Cluster X0072

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
B95-B98 Bacterial, viral and other infectious agents
0.999 0.001 0.000
K92 Other diseases of digestive system
0.999 0.001 0.000
Chapter II Neoplasms
0.999 0.001 0.000
K90-K93 Other diseases of the digestive system
0.999 0.001 0.000
Chapter XX External causes of morbidity and mortality
0.999 0.001 0.000
Chapter XI Diseases of the digestive system
0.998 0.002 0.000
Chapter V Mental and behavioural disorders
0.998 0.002 0.000
J95-J99 Other diseases of the respiratory system
0.998 0.002 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.996 0.004 0.000
J98 Other respiratory disorders
0.996 0.004 0.000
K92.0 Haematemesis
0.996 0.004 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.995 0.005 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.995 0.005 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.993 0.007 0.000
J98.1 Pulmonary collapse
0.993 0.007 0.000
J20-J22 Other acute lower respiratory infections
0.993 0.007 0.000
J22 Unspecified acute lower respiratory infection
0.987 0.013 0.000
Y43 Primarily systemic agents
0.986 0.014 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.985 0.015 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.984 0.016 0.000
K92.1 Melaena
0.984 0.016 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.981 0.019 0.000
Y43.3 Other antineoplastic drugs
0.979 0.021 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.977 0.023 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.976 0.024 0.000
K55-K64 Other diseases of intestines
0.976 0.024 0.000
F30-F39 Mood [affective] disorders
0.976 0.024 0.000
T39.1 4-Aminophenol derivatives
0.976 0.024 0.000
Chapter VI Diseases of the nervous system
0.975 0.025 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.973 0.027 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.971 0.029 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.966 0.034 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.962 0.038 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.959 0.041 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.957 0.043 0.000
D60-D64 Aplastic and other anaemias
0.955 0.045 0.000
G62 Other polyneuropathies
0.952 0.048 0.000
M40-M43 Deforming dorsopathies
0.952 0.048 0.000
D64 Other anaemias
0.950 0.050 0.000
K40-K46 Hernia
0.949 0.051 0.000
D64.9 Anaemia, unspecified
0.947 0.053 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.944 0.056 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.943 0.057 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.941 0.059 0.000
J09-J18 Influenza and pneumonia
0.940 0.060 0.000
M43 Other deforming dorsopathies
0.937 0.063 0.000
G62.9 Polyneuropathy, unspecified
0.935 0.065 0.000
K63 Other diseases of intestine
0.930 0.070 0.000
S20-S29 Injuries to the thorax
0.929 0.071 0.000
M43.1 Spondylolisthesis
0.923 0.077 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.922 0.078 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.922 0.078 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.920 0.080 0.000
C91 Lymphoid leukaemia
0.917 0.083 0.000
K42 Umbilical hernia
0.917 0.083 0.000
M45-M49 Spondylopathies
0.914 0.086 0.000
C85.1 B-cell lymphoma, unspecified
0.908 0.092 0.000
F32 Depressive episode
0.907 0.093 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.903 0.097 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.902 0.098 0.000
F10.3 Withdrawal state
0.900 0.100 0.000
K58 Irritable bowel syndrome
0.898 0.102 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.892 0.108 0.000
C15-C26 Malignant neoplasms of digestive organs
0.890 0.110 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.887 0.113 0.000
T81 Complications of procedures, not elsewhere classified
0.886 0.114 0.000
K62 Other diseases of anus and rectum
0.886 0.114 0.000
K42.9 Umbilical hernia without obstruction or gangrene
0.881 0.119 0.000
M70-M79 Other soft tissue disorders
0.879 0.121 0.000
K55 Vascular disorders of intestine
0.878 0.122 0.000
D00-D09 In situ neoplasms
0.878 0.122 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.874 0.126 0.000
C83.3 Large cell (diffuse)
0.874 0.126 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.873 0.127 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.862 0.138 0.000
K58.9 Irritable bowel syndrome without diarrhoea
0.857 0.143 0.000
Q00-Q07 Congenital malformations of the nervous system
0.851 0.149 0.000
J18 Pneumonia, organism unspecified
0.850 0.150 0.000
K62.6 Ulcer of anus and rectum
0.849 0.151 0.000
F31 Bipolar affective disorder
0.849 0.151 0.000
M86-M90 Other osteopathies
0.849 0.151 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.846 0.154 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.845 0.155 0.000
K63.8 Other specified diseases of intestine
0.844 0.156 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.844 0.156 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.842 0.158 0.000
S20 Superficial injury of thorax
0.842 0.158 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.840 0.160 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.839 0.161 0.000
T93 Sequelae of injuries of lower limb
0.839 0.161 0.000
W00-W19 Falls
0.839 0.161 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.838 0.162 0.000
K60 Fissure and fistula of anal and rectal regions
0.837 0.163 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.835 0.165 0.000
K91.4 Colostomy and enterostomy malfunction
0.835 0.165 0.000
K63.3 Ulcer of intestine
0.831 0.169 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.830 0.170 0.000
G62.0 Drug-induced polyneuropathy
0.829 0.171 0.000
C16 Malignant neoplasm of stomach
0.827 0.173 0.000
F32.1 Moderate depressive episode
0.826 0.174 0.000
Y40 Systemic antibiotics
0.825 0.175 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.822 0.178 0.000
C91.1 Chronic lymphocytic leukaemia
0.822 0.178 0.000
K62.8 Other specified diseases of anus and rectum
0.821 0.179 0.000
S80-S89 Injuries to the knee and lower leg
0.821 0.179 0.000
J98.4 Other disorders of lung
0.820 0.180 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.819 0.181 0.000
S10-S19 Injuries to the neck
0.818 0.182 0.000
J18.1 Lobar pneumonia, unspecified
0.816 0.184 0.000
T81.9 Unspecified complication of procedure
0.815 0.184 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.812 0.188 0.000
S00-S09 Injuries to the head
0.812 0.188 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.811 0.189 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.811 0.189 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.809 0.191 0.000
J98.9 Respiratory disorder, unspecified
0.807 0.193 0.000
O60-O75 Complications of labour and delivery
0.806 0.194 0.000
D61 Other aplastic anaemias
0.804 0.196 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.804 0.196 0.000
X50-X57 Overexertion, travel and privation
0.802 0.197 0.000
F33 Recurrent depressive disorder
0.801 0.199 0.000
Q60-Q64 Congenital malformations of the urinary system
0.797 0.202 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.797 0.202 0.000
C09 Malignant neoplasm of tonsil
0.797 0.203 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.797 0.203 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.795 0.205 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.795 0.205 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.795 0.205 0.000
Y45.1 Salicylates
0.794 0.206 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.793 0.207 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.791 0.209 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.790 0.210 0.000
T92 Sequelae of injuries of upper limb
0.790 0.210 0.000
O63 Long labour
0.790 0.210 0.000
M45 Ankylosing spondylitis
0.788 0.212 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.788 0.212 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.787 0.213 0.000
F10.2 Dependence syndrome
0.787 0.213 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.787 0.213 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.786 0.213 0.000
K43 Ventral hernia
0.786 0.214 0.000
T66-T78 Other and unspecified effects of external causes
0.783 0.217 0.000
K55.2 Angiodysplasia of colon
0.783 0.217 0.000
C15 Malignant neoplasm of oesophagus
0.782 0.217 0.000
K41 Femoral hernia
0.782 0.218 0.000
B91 Sequelae of poliomyelitis
0.781 0.219 0.000
B15-B19 Viral hepatitis
0.779 0.221 0.000
K92.8 Other specified diseases of digestive system
0.779 0.221 0.000
C34 Malignant neoplasm of bronchus and lung
0.779 0.221 0.000
M47 Spondylosis
0.779 0.221 0.000
Q50-Q56 Congenital malformations of genital organs
0.776 0.224 0.000
S20.8 Superficial injuries of other and unspecified parts of thorax
0.775 0.225 0.000
D09 Carcinoma in situ of other and unspecified sites
0.774 0.226 0.000
V40-V49 Car occupant injured in transport accident
0.774 0.226 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.772 0.228 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.772 0.228 0.000
J21 Acute bronchiolitis
0.771 0.229 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.771 0.229 0.000
A15-A19 Tuberculosis
0.769 0.231 0.000
K46 Unspecified abdominal hernia
0.769 0.231 0.000
S90-S99 Injuries to the ankle and foot
0.767 0.233 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.767 0.233 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.767 0.233 0.000
F10.1 Harmful use
0.766 0.234 0.000
C01 Malignant neoplasm of base of tongue
0.765 0.235 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.764 0.236 0.000
F11 Mental and behavioural disorders due to use of opioids
0.763 0.237 0.000
D55-D59 Haemolytic anaemias
0.763 0.237 0.000
C10 Malignant neoplasm of oropharynx
0.763 0.237 0.000
C05 Malignant neoplasm of palate
0.761 0.238 0.000
C91.0 Acute lymphoblastic leukaemia
0.761 0.239 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.758 0.242 0.000
F32.0 Mild depressive episode
0.758 0.242 0.000
C60-C63 Malignant neoplasms of male genital organs
0.758 0.242 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.757 0.242 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.757 0.243 0.000
F30 Manic episode
0.757 0.243 0.000
B02 Zoster [herpes zoster]
0.756 0.244 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.756 0.244 0.000
K60.2 Anal fissure, unspecified
0.756 0.244 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.756 0.244 0.000
S00 Superficial injury of head
0.756 0.244 0.000
S29 Other and unspecified injuries of thorax
0.755 0.244 0.000
T98 Sequelae of other and unspecified effects of external causes
0.753 0.247 0.000
M43.12 Spondylolisthesis (Cervical region)
0.751 0.249 0.000
A30-A49 Other bacterial diseases
0.750 0.250 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.749 0.251 0.000
S70-S79 Injuries to the hip and thigh
0.749 0.251 0.000
K42.0 Umbilical hernia with obstruction, without gangrene
0.749 0.251 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.748 0.252 0.000
O63.0 Prolonged first stage (of labour)
0.748 0.252 0.000
Chapter IX Diseases of the circulatory system
0.748 0.252 0.000
B99-B99 Other infectious diseases
0.747 0.253 0.000
Q05 Spina bifida
0.745 0.255 0.000
C16.0 Cardia
0.743 0.257 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.743 0.257 0.000
C43 Malignant melanoma of skin
0.743 0.257 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.743 0.257 0.000
O63.1 Prolonged second stage (of labour)
0.742 0.258 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.742 0.258 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.742 0.258 0.000
B00 Herpesviral [herpes simplex] infections
0.741 0.259 0.000
B25-B34 Other viral diseases
0.739 0.261 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.739 0.261 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.739 0.261 0.000
Y00-Y09 Assault
0.738 0.262 0.000
M00-M03 Infectious arthropathies
0.738 0.262 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.738 0.262 0.000
M46 Other inflammatory spondylopathies
0.737 0.263 0.000
K63.9 Disease of intestine, unspecified
0.737 0.263 0.000
K45 Other abdominal hernia
0.736 0.264 0.000
S80 Superficial injury of lower leg
0.735 0.265 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.735 0.265 0.000
Y43.1 Antineoplastic antimetabolites
0.735 0.265 0.000
M43.0 Spondylolysis
0.734 0.266 0.000
M79.8 Other specified soft tissue disorders
0.733 0.267 0.000
T91 Sequelae of injuries of neck and trunk
0.732 0.268 0.000
T39.0 Salicylates
0.732 0.268 0.000
C81 Hodgkin's disease
0.732 0.268 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.731 0.269 0.000
F80-F89 Disorders of psychological development
0.731 0.269 0.000
F99-F99 Unspecified mental disorder
0.730 0.270 0.000
W50-W64 Exposure to animate mechanical forces
0.730 0.270 0.000
M60-M63 Disorders of muscles
0.729 0.271 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.728 0.271 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.728 0.272 0.000
S60-S69 Injuries to the wrist and hand
0.727 0.272 0.000
G62.8 Other specified polyneuropathies
0.727 0.273 0.000
W20-W49 Exposure to inanimate mechanical forces
0.726 0.273 0.000
C88 Malignant immunoproliferative diseases
0.726 0.274 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.726 0.274 0.000
F10.9 Unspecified mental and behavioural disorder
0.726 0.274 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.725 0.275 0.000
G59.0 Diabetic mononeuropathy
0.724 0.276 0.000
M43.17 Spondylolisthesis (Lumbosacral region)
0.723 0.277 0.000
C34.3 Lower lobe, bronchus or lung
0.723 0.277 0.000
T79-T79 Certain early complications of trauma
0.723 0.277 0.000
C32 Malignant neoplasm of larynx
0.722 0.278 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.722 0.278 0.000
K55.8 Other vascular disorders of intestine
0.722 0.278 0.000
T87 Complications peculiar to reattachment and amputation
0.721 0.279 0.000
D03 Melanoma in situ
0.721 0.279 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.721 0.279 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.720 0.280 0.000
G30-G32 Other degenerative diseases of the nervous system
0.720 0.280 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.719 0.281 0.000
Q65 Congenital deformities of hip
0.718 0.282 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.717 0.283 0.000
B50-B64 Protozoal diseases
0.717 0.283 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.717 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.717 0.283 0.000
A75-A79 Rickettsioses
0.717 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.717 0.283 0.000
A65-A69 Other spirochaetal diseases
0.717 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.717 0.283 0.000
V80-V89 Other land transport accidents
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.716 0.284 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.716 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.716 0.284 0.000
Y10-Y34 Event of undetermined intent
0.716 0.284 0.000
X85-X99 Assault
0.716 0.284 0.000
X30-X39 Exposure to forces of nature
0.716 0.284 0.000
X20-X29 Contact with venomous animals and plants
0.716 0.284 0.000
X10-X19 Contact with heat and hot substances
0.716 0.284 0.000
X00-X09 Exposure to smoke, fire and flames
0.716 0.284 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.716 0.284 0.000
W75-W84 Other accidental threats to breathing
0.716 0.284 0.000
W65-W74 Accidental drowning and submersion
0.716 0.284 0.000
V98-V99 Other and unspecified transport accidents
0.716 0.284 0.000
V95-V97 Air and space transport accidents
0.716 0.284 0.000
V90-V94 Water transport accidents
0.716 0.284 0.000
V70-V79 Bus occupant injured in transport accident
0.716 0.284 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.716 0.284 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.716 0.284 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.716 0.284 0.000
V01-V09 Pedestrian injured in transport accident
0.716 0.284 0.000
M89 Other disorders of bone
0.716 0.284 0.000
T18 Foreign body in alimentary tract
0.716 0.284 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.715 0.285 0.000
F70-F79 Mental retardation
0.715 0.285 0.000
J96 Respiratory failure, not elsewhere classified
0.715 0.285 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.714 0.286 0.000
C95 Leukaemia of unspecified cell type
0.714 0.286 0.000
C94 Other leukaemias of specified cell type
0.714 0.286 0.000
C93 Monocytic leukaemia
0.714 0.286 0.000
C86 Other specified types of T/NK-cell lymphoma
0.714 0.286 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.714 0.286 0.000
J98.6 Disorders of diaphragm
0.714 0.286 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.714 0.286 0.000
J98.3 Compensatory emphysema
0.714 0.286 0.000
J98.2 Interstitial emphysema
0.714 0.286 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.714 0.286 0.000
Y59 Other and unspecified vaccines and biological substances
0.714 0.286 0.000
Y58 Bacterial vaccines
0.714 0.286 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.714 0.286 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.714 0.286 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.714 0.286 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.714 0.286 0.000
Y48 Anaesthetics and therapeutic gases
0.714 0.286 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.714 0.286 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.714 0.286 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.714 0.286 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.714 0.286 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.712 0.288 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.712 0.288 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.712 0.288 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.712 0.288 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.712 0.288 0.000
T36 Poisoning by systemic antibiotics
0.712 0.288 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.712 0.288 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.711 0.289 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.711 0.289 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.711 0.289 0.000
M87 Osteonecrosis
0.710 0.290 0.000
M79.0 Rheumatism, unspecified
0.709 0.291 0.000
M79.1 Myalgia
0.709 0.291 0.000
F17.2 Dependence syndrome
0.709 0.291 0.000
Y43.9 Primarily systemic agent, unspecified
0.707 0.293 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.707 0.293 0.000
Y43.6 Enzymes, not elsewhere classified
0.707 0.293 0.000
Y43.5 Acidifying and alkalising agents
0.707 0.293 0.000
Y43.2 Antineoplastic natural products
0.707 0.293 0.000
Y43.0 Antiallergic and antiemetic drugs
0.707 0.293 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.706 0.294 0.000
T39.4 Antirheumatics, not elsewhere classified
0.706 0.294 0.000
T39.2 Pyrazolone derivatives
0.706 0.294 0.000
L60-L75 Disorders of skin appendages
0.706 0.294 0.000
J10 Influenza due to identified influenza virus
0.706 0.294 0.000
Q80-Q89 Other congenital malformations
0.706 0.294 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.705 0.294 0.000
Q35-Q37 Cleft lip and cleft palate
0.705 0.294 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.705 0.294 0.000
Q21 Congenital malformations of cardiac septa
0.705 0.295 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.703 0.297 0.000
B65-B83 Helminthiases
0.702 0.298 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.701 0.299 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.701 0.299 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.701 0.299 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.701 0.299 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.701 0.299 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.701 0.299 0.000
V10-V19 Pedal cyclist injured in transport accident
0.701 0.299 0.000
X60-X84 Intentional self-harm
0.701 0.299 0.000
S00.8 Superficial injury of other parts of head
0.701 0.299 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.700 0.300 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.700 0.300 0.000
C85.0 Lymphosarcoma
0.700 0.300 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.700 0.300 0.000
F38 Other mood [affective] disorders
0.700 0.300 0.000
F34 Persistent mood [affective] disorders
0.700 0.300 0.000
F39 Unspecified mood [affective] disorder
0.700 0.300 0.000
D09.0 Bladder
0.699 0.300 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.698 0.302 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.697 0.302 0.000
T86 Failure and rejection of transplanted organs and tissues
0.697 0.303 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.697 0.303 0.000
T17 Foreign body in respiratory tract
0.697 0.303 0.000
I10-I15 Hypertensive diseases
0.696 0.304 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.696 0.304 0.000
C43.5 Malignant melanoma of trunk
0.696 0.304 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.696 0.304 0.000
D07.5 Prostate
0.696 0.304 0.000
J00-J06 Acute upper respiratory infections
0.695 0.304 0.000
K62.9 Disease of anus and rectum, unspecified
0.695 0.305 0.000
C09.9 Tonsil, unspecified
0.694 0.306 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.693 0.307 0.000
C17 Malignant neoplasm of small intestine
0.693 0.307 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.693 0.307 0.000
O62 Abnormalities of forces of labour
0.692 0.308 0.000
F33.9 Recurrent depressive disorder, unspecified
0.692 0.308 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.691 0.309 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.691 0.309 0.000
K43.0 Ventral hernia with obstruction, without gangrene
0.691 0.309 0.000
V20-V29 Motorcycle rider injured in transport accident
0.690 0.310 0.000
F60-F69 Disorders of adult personality and behaviour
0.690 0.310 0.000
G64 Other disorders of peripheral nervous system
0.690 0.310 0.000
L40-L45 Papulosquamous disorders
0.687 0.313 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.687 0.313 0.000
C07 Malignant neoplasm of parotid gland
0.686 0.314 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.684 0.315 0.000
S50-S59 Injuries to the elbow and forearm
0.685 0.315 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.684 0.315 0.000
T93.2 Sequelae of other fractures of lower limb
0.684 0.316 0.000
K60.4 Rectal fistula
0.684 0.316 0.000
D61.1 Drug-induced aplastic anaemia
0.684 0.316 0.000
C83.0 Small cell (diffuse)
0.683 0.316 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.683 0.317 0.000
G62.2 Polyneuropathy due to other toxic agents
0.683 0.317 0.000
G62.1 Alcoholic polyneuropathy
0.683 0.317 0.000
M42 Spinal osteochondrosis
0.683 0.317 0.000
M40 Kyphosis and lordosis
0.683 0.317 0.000
O85-O92 Complications predominantly related to the puerperium
0.682 0.318 0.000
G70-G73 Diseases of myoneural junction and muscle
0.682 0.318 0.000
D64.8 Other specified anaemias
0.681 0.319 0.000
D64.4 Congenital dyserythropoietic anaemia
0.681 0.319 0.000
D64.3 Other sideroblastic anaemias
0.681 0.319 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.681 0.319 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.681 0.319 0.000
D64.0 Hereditary sideroblastic anaemia
0.681 0.319 0.000
F20 Schizophrenia
0.681 0.319 0.000
M91-M94 Chondropathies
0.680 0.319 0.000
C62 Malignant neoplasm of testis
0.680 0.320 0.000
W10 Fall on and from stairs and steps
0.680 0.320 0.000
C64-C68 Malignant neoplasms of urinary tract
0.680 0.320 0.000
D80-D89 Certain disorders involving the immune mechanism
0.680 0.320 0.000
B35-B49 Mycoses
0.680 0.320 0.000
O66 Other obstructed labour
0.679 0.320 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.679 0.321 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.679 0.321 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.679 0.321 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.678 0.322 0.000
S62 Fracture at wrist and hand level
0.678 0.322 0.000
M79.2 Neuralgia and neuritis, unspecified
0.677 0.323 0.000
T95 Sequelae of burns, corrosions and frostbite
0.677 0.323 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.677 0.323 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.677 0.323 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.677 0.323 0.000
T45.0 Antiallergic and antiemetic drugs
0.677 0.323 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.677 0.323 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.677 0.323 0.000
F10.8 Other mental and behavioural disorders
0.676 0.324 0.000
F10.7 Residual and late-onset psychotic disorder
0.676 0.324 0.000
F10.6 Amnesic syndrome
0.676 0.324 0.000
F10.5 Psychotic disorder
0.676 0.324 0.000
I05-I09 Chronic rheumatic heart diseases
0.676 0.324 0.000
S86 Injury of muscle and tendon at lower leg level
0.676 0.324 0.000
Y54.5 Other diuretics
0.676 0.324 0.000
K63.2 Fistula of intestine
0.676 0.324 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.674 0.325 0.000
C13 Malignant neoplasm of hypopharynx
0.674 0.325 0.000
C11 Malignant neoplasm of nasopharynx
0.674 0.325 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.674 0.325 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.674 0.325 0.000
C04 Malignant neoplasm of floor of mouth
0.674 0.325 0.000
C03 Malignant neoplasm of gum
0.674 0.325 0.000
C00 Malignant neoplasm of lip
0.674 0.325 0.000
C12 Malignant neoplasm of pyriform sinus
0.674 0.325 0.000
J17 Pneumonia in diseases classified elsewhere
0.674 0.326 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.674 0.326 0.000
J12 Viral pneumonia, not elsewhere classified
0.674 0.326 0.000
J11 Influenza, virus not identified
0.674 0.326 0.000
J09 Influenza due to certain identified influenza virus
0.674 0.326 0.000
M47.8 Other spondylosis
0.674 0.326 0.000
J15.0 Pneumonia due to Klebsiella pneumoniae
0.672 0.328 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.672 0.328 0.000
M43.9 Deforming dorsopathy, unspecified
0.672 0.328 0.000
M43.8 Other specified deforming dorsopathies
0.672 0.328 0.000
M43.6 Torticollis
0.672 0.328 0.000
M43.5 Other recurrent vertebral subluxation
0.672 0.328 0.000
M43.4 Other recurrent atlantoaxial subluxation
0.672 0.328 0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy
0.672 0.328 0.000
M43.2 Other fusion of spine
0.672 0.328 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.671 0.329 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.670 0.329 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.670 0.330 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.670 0.330 0.000
Q05.9 Spina bifida, unspecified
0.669 0.331 0.000
A80-A89 Viral infections of the central nervous system
0.669 0.331 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.669 0.331 0.000
J20 Acute bronchitis
0.669 0.331 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.669 0.331 0.000
G54 Nerve root and plexus disorders
0.668 0.332 0.000
G60 Hereditary and idiopathic neuropathy
0.667 0.333 0.000
K62.7 Radiation proctitis
0.667 0.333 0.000
K63.4 Enteroptosis
0.666 0.333 0.000
K63.0 Abscess of intestine
0.666 0.333 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.666 0.334 0.000
S26 Injury of heart
0.666 0.334 0.000
S25 Injury of blood vessels of thorax
0.666 0.334 0.000
S24 Injury of nerves and spinal cord at thorax level
0.666 0.334 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.666 0.334 0.000
S21 Open wound of thorax
0.666 0.334 0.000
M71 Other bursopathies
0.666 0.334 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.664 0.336 0.000
C16.5 Lesser curvature of stomach, unspecified
0.664 0.336 0.000
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene
0.664 0.336 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.664 0.336 0.000
C34.0 Main bronchus
0.663 0.336 0.000
K55.9 Vascular disorder of intestine, unspecified
0.663 0.337 0.000
M80-M85 Disorders of bone density and structure
0.663 0.337 0.000
M43.19 Spondylolisthesis (Site unspecified)
0.662 0.338 0.000
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)
0.662 0.338 0.000
M43.15 Spondylolisthesis (Thoracolumbar region)
0.662 0.338 0.000
M43.14 Spondylolisthesis (Thoracic region)
0.662 0.338 0.000
M43.13 Spondylolisthesis (Cervicothoracic region)
0.662 0.338 0.000
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)
0.662 0.338 0.000
M43.10 Spondylolisthesis (Multiple sites in spine)
0.662 0.338 0.000
Y44 Agents primarily affecting blood constituents
0.662 0.338 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.661 0.339 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.661 0.339 0.000
C83.7 Burkitt's tumour
0.661 0.339 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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