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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75116029
log Bayes Factor = 15.377
Chromosome 16   position 13,489,294  (GRCh37) Explore rs75116029 on Ensembl!
Variant rs75116029 is part of Cluster X0320

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
E65-E68 Obesity and other hyperalimentation
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
E66 Obesity
0.998 0.002 0.000
E66.9 Obesity, unspecified
0.998 0.002 0.000
Chapter V Mental and behavioural disorders
0.996 0.004 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.995 0.005 0.000
K50-K52 Noninfective enteritis and colitis
0.994 0.006 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.990 0.010 0.000
E70-E90 Metabolic disorders
0.989 0.011 0.000
M05-M14 Inflammatory polyarthropathies
0.988 0.012 0.000
K30 Dyspepsia
0.988 0.012 0.000
Chapter XX External causes of morbidity and mortality
0.988 0.012 0.000
K50 Crohn's disease [regional enteritis]
0.985 0.015 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.983 0.017 0.000
M13 Other arthritis
0.982 0.018 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.980 0.020 0.000
M13.9 Arthritis, unspecified
0.977 0.023 0.000
K55-K64 Other diseases of intestines
0.976 0.024 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.976 0.024 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.974 0.026 0.000
F41 Other anxiety disorders
0.967 0.033 0.000
M70-M79 Other soft tissue disorders
0.959 0.041 0.000
K57 Diverticular disease of intestine
0.958 0.042 0.000
K50.9 Crohn's disease, unspecified
0.956 0.044 0.000
K57.3 Diverticular disease of large intestine without perforation or abscess
0.952 0.048 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.950 0.050 0.000
Chapter XIV Diseases of the genitourinary system
0.942 0.058 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.939 0.061 0.000
E86 Volume depletion
0.938 0.062 0.000
N10-N16 Renal tubulo-interstitial diseases
0.932 0.068 0.000
Chapter X Diseases of the respiratory system
0.927 0.073 0.000
R50-R69 General symptoms and signs
0.925 0.075 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.924 0.076 0.000
F41.2 Mixed anxiety and depressive disorder
0.918 0.082 0.000
M15-M19 Arthrosis
0.918 0.082 0.000
M75 Shoulder lesions
0.918 0.082 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.917 0.083 0.000
N13 Obstructive and reflux uropathy
0.917 0.083 0.000
Chapter VI Diseases of the nervous system
0.916 0.084 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.916 0.084 0.000
K26 Duodenal ulcer
0.911 0.089 0.000
R94 Abnormal results of function studies
0.905 0.095 0.000
E87.2 Acidosis
0.902 0.098 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.901 0.099 0.000
S40-S49 Injuries to the shoulder and upper arm
0.898 0.102 0.000
M20-M25 Other joint disorders
0.896 0.104 0.000
J90-J94 Other diseases of pleura
0.893 0.107 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.893 0.107 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.892 0.108 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.891 0.109 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.890 0.110 0.000
K21 Gastro-oesophageal reflux disease
0.886 0.114 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.886 0.114 0.000
K82 Other diseases of gallbladder
0.885 0.115 0.000
M19 Other arthrosis
0.884 0.116 0.000
K51 Ulcerative colitis
0.883 0.117 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.878 0.122 0.000
J09-J18 Influenza and pneumonia
0.876 0.124 0.000
N13.3 Other and unspecified hydronephrosis
0.875 0.125 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.874 0.126 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.873 0.127 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.870 0.130 0.000
K50.1 Crohn's disease of large intestine
0.867 0.133 0.000
K21.9 Gastro-oesophageal reflux disease without oesophagitis
0.864 0.136 0.000
R94.5 Abnormal results of liver function studies
0.863 0.137 0.000
E87.5 Hyperkalaemia
0.858 0.142 0.000
R53 Malaise and fatigue
0.857 0.143 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.855 0.145 0.000
J90 Pleural effusion, not elsewhere classified
0.854 0.146 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.853 0.147 0.000
K56.2 Volvulus
0.852 0.148 0.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.845 0.155 0.000
K82.8 Other specified diseases of gallbladder
0.842 0.158 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.842 0.158 0.000
K02 Dental caries
0.839 0.161 0.000
R14 Flatulence and related conditions
0.838 0.162 0.000
S90-S99 Injuries to the ankle and foot
0.836 0.164 0.000
Chapter VII Diseases of the eye and adnexa
0.836 0.164 0.000
N73 Other female pelvic inflammatory diseases
0.834 0.166 0.000
M75.4 Impingement syndrome of shoulder
0.834 0.166 0.000
K20 Oesophagitis
0.834 0.166 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.828 0.172 0.000
R60 Oedema, not elsewhere classified
0.827 0.173 0.000
F30-F39 Mood [affective] disorders
0.827 0.173 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.826 0.174 0.000
M91-M94 Chondropathies
0.825 0.175 0.000
R50 Fever of unknown origin
0.824 0.176 0.000
F60-F69 Disorders of adult personality and behaviour
0.824 0.176 0.000
R47-R49 Symptoms and signs involving speech and voice
0.823 0.177 0.000
R63 Symptoms and signs concerning food and fluid intake
0.820 0.180 0.000
S70-S79 Injuries to the hip and thigh
0.819 0.181 0.000
E66.8 Other obesity
0.817 0.183 0.000
F43 Reaction to severe stress, and adjustment disorders
0.817 0.183 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.814 0.186 0.000
W20-W49 Exposure to inanimate mechanical forces
0.814 0.186 0.000
K61 Abscess of anal and rectal regions
0.813 0.187 0.000
M19.0 Primary arthrosis of other joints
0.812 0.188 0.000
J18 Pneumonia, organism unspecified
0.808 0.192 0.000
K11 Diseases of salivary glands
0.806 0.194 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.806 0.194 0.000
K50.8 Other Crohn's disease
0.804 0.196 0.000
R18 Ascites
0.802 0.198 0.000
K02.9 Dental caries, unspecified
0.801 0.199 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.801 0.199 0.000
M19.9 Arthrosis, unspecified
0.801 0.199 0.000
N73.6 Female pelvic peritoneal adhesions
0.800 0.200 0.000
T79-T79 Certain early complications of trauma
0.800 0.200 0.000
M75.5 Bursitis of shoulder
0.799 0.201 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.797 0.202 0.000
V20-V29 Motorcycle rider injured in transport accident
0.797 0.203 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.797 0.203 0.000
E10-E14 Diabetes mellitus
0.795 0.205 0.000
R10 Abdominal and pelvic pain
0.795 0.205 0.000
J18.1 Lobar pneumonia, unspecified
0.794 0.206 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.793 0.207 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.787 0.213 0.000
G90-G99 Other disorders of the nervous system
0.786 0.214 0.000
M21 Other acquired deformities of limbs
0.785 0.215 0.000
R16.0 Hepatomegaly, not elsewhere classified
0.783 0.217 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.780 0.220 0.000
K50.0 Crohn's disease of small intestine
0.779 0.221 0.000
T81 Complications of procedures, not elsewhere classified
0.779 0.221 0.000
K35-K38 Diseases of appendix
0.779 0.221 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.776 0.224 0.000
M20 Acquired deformities of fingers and toes
0.774 0.226 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.774 0.226 0.000
H40-H42 Glaucoma
0.774 0.226 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.773 0.227 0.000
E50-E64 Other nutritional deficiencies
0.772 0.228 0.000
R50.9 Fever, unspecified
0.771 0.229 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.770 0.230 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.769 0.231 0.000
M11 Other crystal arthropathies
0.766 0.234 0.000
G81 Hemiplegia
0.766 0.234 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.765 0.235 0.000
T66-T78 Other and unspecified effects of external causes
0.764 0.236 0.000
F80-F89 Disorders of psychological development
0.764 0.236 0.000
K22 Other diseases of oesophagus
0.764 0.236 0.000
Y95 Nosocomial condition
0.760 0.240 0.000
K63 Other diseases of intestine
0.760 0.240 0.000
K65-K67 Diseases of peritoneum
0.758 0.242 0.000
V10-V19 Pedal cyclist injured in transport accident
0.757 0.243 0.000
R94.3 Abnormal results of cardiovascular function studies
0.757 0.243 0.000
M75.0 Adhesive capsulitis of shoulder
0.757 0.243 0.000
S43.0 Dislocation of shoulder joint
0.754 0.246 0.000
Chapter XXII Codes for special purposes
0.753 0.247 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.750 0.250 0.000
M16 Coxarthrosis [arthrosis of hip]
0.747 0.253 0.000
E14 Unspecified diabetes mellitus
0.745 0.255 0.000
M31 Other necrotising vasculopathies
0.745 0.255 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.744 0.256 0.000
E20-E35 Disorders of other endocrine glands
0.742 0.257 0.000
N17-N19 Renal failure
0.743 0.257 0.000
Y83.3 Surgical operation with formation of external stoma
0.742 0.258 0.000
X60-X84 Intentional self-harm
0.741 0.259 0.000
M19.04 Primary arthrosis of other joints (Hand)
0.740 0.260 0.000
K86 Other diseases of pancreas
0.740 0.260 0.000
N70 Salpingitis and oophoritis
0.739 0.261 0.000
F41.9 Anxiety disorder, unspecified
0.739 0.261 0.000
S10-S19 Injuries to the neck
0.738 0.262 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.737 0.263 0.000
K90-K93 Other diseases of the digestive system
0.735 0.265 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.735 0.265 0.000
K63.8 Other specified diseases of intestine
0.731 0.269 0.000
S80-S89 Injuries to the knee and lower leg
0.731 0.269 0.000
M72 Fibroblastic disorders
0.730 0.270 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.730 0.270 0.000
H40 Glaucoma
0.730 0.270 0.000
J95-J99 Other diseases of the respiratory system
0.730 0.270 0.000
K70-K77 Diseases of liver
0.728 0.271 0.000
K27 Peptic ulcer, site unspecified
0.727 0.273 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.725 0.275 0.000
K51.9 Ulcerative colitis, unspecified
0.723 0.277 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.723 0.277 0.000
J92 Pleural plaque
0.722 0.278 0.000
J91 Pleural effusion in conditions classified elsewhere
0.722 0.278 0.000
J60-J70 Lung diseases due to external agents
0.722 0.278 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.722 0.278 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.721 0.278 0.000
G81.9 Hemiplegia, unspecified
0.721 0.279 0.000
M65-M68 Disorders of synovium and tendon
0.720 0.280 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.720 0.280 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.719 0.281 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.718 0.282 0.000
M86-M90 Other osteopathies
0.717 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E40-E46 Malnutrition
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
E67 Other hyperalimentation
0.716 0.284 0.000
E68 Sequelae of hyperalimentation
0.716 0.284 0.000
E65 Localised adiposity
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.716 0.284 0.000
E66.1 Drug-induced obesity
0.716 0.284 0.000
E66.0 Obesity due to excess calories
0.716 0.284 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.716 0.284 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.714 0.286 0.000
F70-F79 Mental retardation
0.714 0.286 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.714 0.286 0.000
M77 Other enthesopathies
0.713 0.287 0.000
F33 Recurrent depressive disorder
0.713 0.287 0.000
K28 Gastrojejunal ulcer
0.713 0.287 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.713 0.287 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.711 0.289 0.000
R60.0 Localised oedema
0.711 0.289 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.711 0.289 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.711 0.289 0.000
K82.4 Cholesterolosis of gallbladder
0.711 0.289 0.000
K09 Cysts of oral region, not elsewhere classified
0.711 0.289 0.000
T87 Complications peculiar to reattachment and amputation
0.710 0.290 0.000
T86 Failure and rejection of transplanted organs and tissues
0.710 0.290 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.710 0.290 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.710 0.290 0.000
E87.7 Fluid overload
0.709 0.290 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.709 0.291 0.000
G20-G26 Extrapyramidal and movement disorders
0.709 0.291 0.000
E85 Amyloidosis
0.709 0.291 0.000
E84 Cystic fibrosis
0.709 0.291 0.000
E79 Disorders of purine and pyrimidine metabolism
0.709 0.291 0.000
E77 Disorders of glycoprotein metabolism
0.709 0.291 0.000
E76 Disorders of glycosaminoglycan metabolism
0.709 0.291 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.709 0.291 0.000
E74 Other disorders of carbohydrate metabolism
0.709 0.291 0.000
E73 Lactose intolerance
0.709 0.291 0.000
E72 Other disorders of amino-acid metabolism
0.709 0.291 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.709 0.291 0.000
E70 Disorders of aromatic amino-acid metabolism
0.709 0.291 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.709 0.291 0.000
M14 Arthropathies in other diseases classified elsewhere
0.708 0.292 0.000
M12 Other specific arthropathies
0.708 0.292 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.708 0.292 0.000
M08 Juvenile arthritis
0.708 0.292 0.000
M07 Psoriatic and enteropathic arthropathies
0.708 0.292 0.000
M05 Seropositive rheumatoid arthritis
0.708 0.292 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.708 0.292 0.000
Y35-Y36 Legal intervention and operations of war
0.708 0.292 0.000
Y10-Y34 Event of undetermined intent
0.708 0.292 0.000
Y00-Y09 Assault
0.708 0.292 0.000
X85-X99 Assault
0.708 0.292 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.708 0.292 0.000
X50-X57 Overexertion, travel and privation
0.708 0.292 0.000
X30-X39 Exposure to forces of nature
0.708 0.292 0.000
X20-X29 Contact with venomous animals and plants
0.708 0.292 0.000
X10-X19 Contact with heat and hot substances
0.708 0.292 0.000
X00-X09 Exposure to smoke, fire and flames
0.708 0.292 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.708 0.292 0.000
W75-W84 Other accidental threats to breathing
0.708 0.292 0.000
W65-W74 Accidental drowning and submersion
0.708 0.292 0.000
W50-W64 Exposure to animate mechanical forces
0.708 0.292 0.000
V98-V99 Other and unspecified transport accidents
0.708 0.292 0.000
V95-V97 Air and space transport accidents
0.708 0.292 0.000
V90-V94 Water transport accidents
0.708 0.292 0.000
V80-V89 Other land transport accidents
0.708 0.292 0.000
V70-V79 Bus occupant injured in transport accident
0.708 0.292 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.708 0.292 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.708 0.292 0.000
V40-V49 Car occupant injured in transport accident
0.708 0.292 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.708 0.292 0.000
V01-V09 Pedestrian injured in transport accident
0.708 0.292 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.706 0.294 0.000
W22 Striking against or struck by other objects
0.705 0.294 0.000
F48 Other neurotic disorders
0.704 0.295 0.000
F45 Somatoform disorders
0.704 0.295 0.000
F44 Dissociative [conversion] disorders
0.704 0.295 0.000
F42 Obsessive-compulsive disorder
0.704 0.295 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.704 0.296 0.000
M13.8 Other specified arthritis
0.704 0.296 0.000
M13.1 Monoarthritis, not elsewhere classified
0.704 0.296 0.000
M13.0 Polyarthritis, unspecified
0.704 0.296 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.702 0.297 0.000
S60-S69 Injuries to the wrist and hand
0.702 0.298 0.000
F99-F99 Unspecified mental disorder
0.701 0.298 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.701 0.299 0.000
N25-N29 Other disorders of kidney and ureter
0.701 0.299 0.000
M94 Other disorders of cartilage
0.701 0.299 0.000
M13.98 Arthritis, unspecified (Other)
0.700 0.299 0.000
M13.93 Arthritis, unspecified (Forearm)
0.700 0.299 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.700 0.299 0.000
F60 Specific personality disorders
0.700 0.300 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.699 0.300 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.699 0.300 0.000
E87.4 Mixed disorder of acid-base balance
0.699 0.300 0.000
E87.3 Alkalosis
0.699 0.300 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.699 0.300 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.699 0.301 0.000
R68 Other general symptoms and signs
0.698 0.301 0.000
F31 Bipolar affective disorder
0.698 0.302 0.000
R54 Senility
0.698 0.302 0.000
H10-H13 Disorders of conjunctiva
0.698 0.302 0.000
K82.1 Hydrops of gallbladder
0.698 0.302 0.000
T85.2 Mechanical complication of intraocular lens
0.698 0.302 0.000
K61.0 Anal abscess
0.696 0.303 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.696 0.304 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.694 0.306 0.000
R63.4 Abnormal weight loss
0.694 0.306 0.000
J10 Influenza due to identified influenza virus
0.694 0.306 0.000
F41.8 Other specified anxiety disorders
0.693 0.307 0.000
F41.3 Other mixed anxiety disorders
0.693 0.307 0.000
F41.1 Generalised anxiety disorder
0.693 0.307 0.000
F40 Phobic anxiety disorders
0.693 0.307 0.000
R47 Speech disturbances, not elsewhere classified
0.693 0.307 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.691 0.309 0.000
K51.4 Pseudopolyposis of colon
0.690 0.310 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.690 0.310 0.000
J14 Pneumonia due to Haemophilus influenzae
0.689 0.311 0.000
M80-M85 Disorders of bone density and structure
0.688 0.312 0.000
M76 Enthesopathies of lower limb, excluding foot
0.688 0.312 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.688 0.312 0.000
M71 Other bursopathies
0.688 0.312 0.000
N00-N08 Glomerular diseases
0.687 0.313 0.000
K11.2 Sialoadenitis
0.687 0.313 0.000
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess
0.687 0.313 0.000
K57.5 Diverticular disease of both small and large intestine without perforation or abscess
0.687 0.313 0.000
K57.4 Diverticular disease of both small and large intestine with perforation and abscess
0.687 0.313 0.000
K57.0 Diverticular disease of small intestine with perforation and abscess
0.687 0.313 0.000
M75.2 Bicipital tendinitis
0.686 0.313 0.000
N13.4 Hydroureter
0.686 0.314 0.000
M10 Gout
0.686 0.314 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.686 0.314 0.000
R60.9 Oedema, unspecified
0.685 0.315 0.000
E88 Other metabolic disorders
0.684 0.315 0.000
K35 Acute appendicitis
0.684 0.316 0.000
S92 Fracture of foot, except ankle
0.684 0.316 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.684 0.316 0.000
S50-S59 Injuries to the elbow and forearm
0.684 0.316 0.000
M40-M43 Deforming dorsopathies
0.682 0.317 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.682 0.317 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.682 0.318 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.681 0.319 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.681 0.319 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.681 0.319 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.681 0.319 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.681 0.319 0.000
R63.0 Anorexia
0.680 0.320 0.000
K26.4 Chronic or unspecified with haemorrhage
0.679 0.320 0.000
N13.8 Other obstructive and reflux uropathy
0.679 0.321 0.000
Chapter I Certain infectious and parasitic diseases
0.679 0.321 0.000
N18 Chronic renal failure
0.679 0.321 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.678 0.322 0.000
S42 Fracture of shoulder and upper arm
0.678 0.322 0.000
E14.9 Without complications
0.678 0.322 0.000
F10.1 Harmful use
0.678 0.322 0.000
T81.9 Unspecified complication of procedure
0.677 0.323 0.000
K56.6 Other and unspecified intestinal obstruction
0.675 0.325 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.674 0.326 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.674 0.326 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.674 0.326 0.000
G30-G32 Other degenerative diseases of the nervous system
0.673 0.326 0.000
R52 Pain, not elsewhere classified
0.673 0.327 0.000
K55 Vascular disorders of intestine
0.673 0.327 0.000
F43.1 Posttraumatic stress disorder
0.673 0.327 0.000
R10.1 Pain localised to upper abdomen
0.673 0.327 0.000
M75.3 Calcific tendinitis of shoulder
0.671 0.329 0.000
R59 Enlarged lymph nodes
0.670 0.330 0.000
M16.0 Primary coxarthrosis, bilateral
0.669 0.331 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.668 0.332 0.000
N15 Other renal tubulo-interstitial diseases
0.668 0.332 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.668 0.332 0.000
N11 Chronic tubulo-interstitial nephritis
0.668 0.332 0.000
N10 Acute tubulo-interstitial nephritis
0.668 0.332 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.668 0.332 0.000
Y40 Systemic antibiotics
0.668 0.332 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.667 0.333 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.667 0.333 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.667 0.333 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.665 0.335 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.665 0.335 0.000
K58 Irritable bowel syndrome
0.665 0.335 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.665 0.335 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.663 0.337 0.000
R62 Lack of expected normal physiological development
0.663 0.337 0.000
R57 Shock, not elsewhere classified
0.663 0.337 0.000
R64 Cachexia
0.663 0.337 0.000
R58 Haemorrhage, not elsewhere classified
0.663 0.337 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.662 0.337 0.000
N99-N99 Other disorders of the genitourinary system
0.662 0.338 0.000
Y52 Agents primarily affecting the cardiovascular system
0.662 0.338 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.661 0.339 0.000
M15 Polyarthrosis
0.658 0.342 0.000
M75.8 Other shoulder lesions
0.658 0.342 0.000
M75.9 Shoulder lesion, unspecified
0.658 0.342 0.000
M20.5 Other deformities of toe(s) (acquired)
0.658 0.342 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.658 0.342 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.658 0.342 0.000
N13.6 Pyonephrosis
0.658 0.342 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.658 0.342 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.657 0.343 0.000
R69 Unknown and unspecified causes of morbidity
0.657 0.343 0.000
G70-G73 Diseases of myoneural junction and muscle
0.657 0.343 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.656 0.343 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.656 0.344 0.000
K26.3 Acute without haemorrhage or perforation
0.655 0.345 0.000
M20.2 Hallux rigidus
0.655 0.345 0.000
F10.4 Withdrawal state with delirium
0.655 0.345 0.000
K05 Gingivitis and periodontal diseases
0.654 0.346 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.654 0.346 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.654 0.346 0.000
K26.7 Chronic without haemorrhage or perforation
0.653 0.346 0.000
K26.6 Chronic or unspecified with both haemorrhage and perforation
0.653 0.346 0.000
K26.5 Chronic or unspecified with perforation
0.653 0.346 0.000
K26.2 Acute with both haemorrhage and perforation
0.653 0.346 0.000
K26.1 Acute with perforation
0.653 0.346 0.000
K26.0 Acute with haemorrhage
0.653 0.346 0.000
Y83.6 Removal of other organ (partial) (total)
0.653 0.347 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.651 0.349 0.000
H55-H59 Other disorders of eye and adnexa
0.650 0.350 0.000
Y42.5 Other oestrogens and progestogens
0.649 0.351 0.000
R94.8 Abnormal results of function studies of other organs and systems
0.649 0.351 0.000
R94.7 Abnormal results of other endocrine function studies
0.649 0.351 0.000
R94.6 Abnormal results of thyroid function studies
0.649 0.351 0.000
R94.4 Abnormal results of kidney function studies
0.649 0.351 0.000
R94.2 Abnormal results of pulmonary function studies
0.649 0.351 0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses
0.649 0.351 0.000
R94.0 Abnormal results of function studies of central nervous system
0.649 0.351 0.000
K11.1 Hypertrophy of salivary gland
0.648 0.352 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.648 0.352 0.000
M50-M54 Other dorsopathies
0.648 0.352 0.000
Y44 Agents primarily affecting blood constituents
0.647 0.353 0.000
M21.6 Other acquired deformities of ankle and foot
0.646 0.354 0.000
K56.4 Other impaction of intestine
0.646 0.354 0.000
K56.3 Gallstone ileus
0.646 0.354 0.000
K56.1 Intussusception
0.646 0.354 0.000
K56.0 Paralytic ileus
0.646 0.354 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.645 0.355 0.000
K51.2 Ulcerative (chronic) proctitis
0.645 0.355 0.000
E87.6 Hypokalaemia
0.644 0.355 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.644 0.356 0.000
S48 Traumatic amputation of shoulder and upper arm
0.644 0.356 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.644 0.356 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.644 0.356 0.000
S44 Injury of nerves at shoulder and upper arm level
0.644 0.356 0.000
S41 Open wound of shoulder and upper arm
0.644 0.356 0.000
S40 Superficial injury of shoulder and upper arm
0.644 0.356 0.000
S47 Crushing injury of shoulder and upper arm
0.644 0.356 0.000
R13 Dysphagia
0.643 0.357 0.000
S72 Fracture of femur
0.643 0.357 0.000
S71 Open wound of hip and thigh
0.643 0.357 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.642 0.358 0.000
M34 Systemic sclerosis
0.642 0.358 0.000
M33 Dermatopolymyositis
0.642 0.358 0.000
M32 Systemic lupus erythematosus
0.642 0.358 0.000
M30 Polyarteritis nodosa and related conditions
0.642 0.358 0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.642 0.358 0.000
M19.94 Arthrosis, unspecified (Hand)
0.641 0.359 0.000
J94 Other pleural conditions
0.640 0.359 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.640 0.359 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.640 0.359 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.640 0.359 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.640 0.359 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.640 0.359 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.640 0.359 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.640 0.359 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.640 0.359 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.640 0.359 0.000
T36 Poisoning by systemic antibiotics
0.640 0.359 0.000
R10.0 Acute abdomen
0.640 0.360 0.000
K10 Other diseases of jaws
0.639 0.361 0.000
K03 Other diseases of hard tissues of teeth
0.639 0.361 0.000
K00 Disorders of tooth development and eruption
0.639 0.361 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.638 0.362 0.000
K11.5 Sialolithiasis
0.638 0.362 0.000
M22 Disorders of patella
0.638 0.362 0.000
F43.0 Acute stress reaction
0.638 0.362 0.000
Y59 Other and unspecified vaccines and biological substances
0.638 0.362 0.000
Y58 Bacterial vaccines
0.638 0.362 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.638 0.362 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.638 0.362 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.638 0.362 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.638 0.362 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.638 0.362 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.638 0.362 0.000
Y48 Anaesthetics and therapeutic gases
0.638 0.362 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.638 0.362 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.638 0.362 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.638 0.362 0.000
M31.6 Other giant cell arteritis
0.638 0.362 0.000
Y83.4 Other reconstructive surgery
0.635 0.365 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.635 0.365 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.635 0.365 0.000
N71 Inflammatory disease of uterus, except cervix
0.635 0.365 0.000
K82.9 Disease of gallbladder, unspecified
0.634 0.366 0.000
K82.3 Fistula of gallbladder
0.634 0.366 0.000
K82.2 Perforation of gallbladder
0.634 0.366 0.000
K82.0 Obstruction of gallbladder
0.634 0.366 0.000
E14.3 With ophthalmic complications
0.634 0.366 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.634 0.366 0.000
M19.8 Other specified arthrosis
0.634 0.366 0.000
M19.2 Other secondary arthrosis
0.634 0.366 0.000
M19.1 Posttraumatic arthrosis of other joints
0.634 0.366 0.000
H40.2 Primary angle-closure glaucoma
0.634 0.366 0.000
M19.01 Primary arthrosis of other joints (Shoulder region)
0.634 0.366 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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