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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75123980
log Bayes Factor = 11.1185
Chromosome 1   position 159,798,486  (GRCh37) Explore rs75123980 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
S00-S09 Injuries to the head
0.995 0.005 0.000
Chapter V Mental and behavioural disorders
0.995 0.005 0.000
M70-M79 Other soft tissue disorders
0.993 0.007 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.992 0.008 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.990 0.010 0.000
E10-E14 Diabetes mellitus
0.989 0.011 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.989 0.011 0.000
M79.6 Pain in limb
0.985 0.015 0.000
M79.66 Pain in limb (Lower leg)
0.984 0.016 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.981 0.019 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.980 0.020 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.980 0.020 0.000
Chapter XX External causes of morbidity and mortality
0.976 0.024 0.000
E20-E35 Disorders of other endocrine glands
0.974 0.026 0.000
E14 Unspecified diabetes mellitus
0.973 0.027 0.000
S01 Open wound of head
0.971 0.029 0.000
S00 Superficial injury of head
0.968 0.032 0.000
M79.8 Other specified soft tissue disorders
0.967 0.033 0.000
E14.9 Without complications
0.965 0.035 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.962 0.038 0.000
M80-M85 Disorders of bone density and structure
0.959 0.041 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.958 0.042 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.955 0.045 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.951 0.049 0.000
S00.0 Superficial injury of scalp
0.951 0.049 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.951 0.049 0.000
E11 Non-insulin-dependent diabetes mellitus
0.949 0.051 0.000
S50-S59 Injuries to the elbow and forearm
0.945 0.055 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.941 0.059 0.000
F17.2 Dependence syndrome
0.939 0.061 0.000
S20-S29 Injuries to the thorax
0.934 0.066 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.934 0.066 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.934 0.066 0.000
T93 Sequelae of injuries of lower limb
0.933 0.067 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.933 0.067 0.000
E11.9 Without complications
0.931 0.069 0.000
M81 Osteoporosis without pathological fracture
0.927 0.073 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.925 0.075 0.000
M05-M14 Inflammatory polyarthropathies
0.922 0.078 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.913 0.087 0.000
D60-D64 Aplastic and other anaemias
0.912 0.088 0.000
L20-L30 Dermatitis and eczema
0.910 0.090 0.000
M81.9 Osteoporosis, unspecified
0.907 0.093 0.000
F10.1 Harmful use
0.907 0.093 0.000
S00.8 Superficial injury of other parts of head
0.903 0.097 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.899 0.101 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.899 0.101 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.897 0.103 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.890 0.110 0.000
L91 Hypertrophic disorders of skin
0.889 0.111 0.000
S32 Fracture of lumbar spine and pelvis
0.888 0.112 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.886 0.114 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.885 0.115 0.000
Y95 Nosocomial condition
0.883 0.117 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.880 0.120 0.000
E27 Other disorders of adrenal gland
0.880 0.120 0.000
Y52 Agents primarily affecting the cardiovascular system
0.876 0.124 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.874 0.126 0.000
L50-L54 Urticaria and erythema
0.871 0.129 0.000
M20-M25 Other joint disorders
0.862 0.138 0.000
M10 Gout
0.860 0.140 0.000
W20-W49 Exposure to inanimate mechanical forces
0.857 0.143 0.000
L82 Seborrhoeic keratosis
0.857 0.143 0.000
T93.2 Sequelae of other fractures of lower limb
0.856 0.144 0.000
M79.69 Pain in limb (Site unspecified)
0.855 0.145 0.000
D61 Other aplastic anaemias
0.854 0.146 0.000
S51 Open wound of forearm
0.854 0.146 0.000
S01.0 Open wound of scalp
0.852 0.148 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.852 0.148 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.851 0.149 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.851 0.149 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.850 0.150 0.000
Chapter VII Diseases of the eye and adnexa
0.849 0.151 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.845 0.155 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.845 0.155 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.843 0.157 0.000
E70-E90 Metabolic disorders
0.842 0.158 0.000
T91 Sequelae of injuries of neck and trunk
0.837 0.163 0.000
S01.9 Open wound of head, part unspecified
0.834 0.166 0.000
M25 Other joint disorders, not elsewhere classified
0.832 0.168 0.000
S22.3 Fracture of rib
0.828 0.172 0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.828 0.172 0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.827 0.173 0.000
S10-S19 Injuries to the neck
0.825 0.175 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.825 0.175 0.000
L98.0 Pyogenic granuloma
0.824 0.176 0.000
F99-F99 Unspecified mental disorder
0.822 0.178 0.000
S01.4 Open wound of cheek and temporomandibular area
0.820 0.180 0.000
F10.3 Withdrawal state
0.818 0.182 0.000
M10.9 Gout, unspecified
0.816 0.184 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.815 0.185 0.000
S01.7 Multiple open wounds of head
0.814 0.186 0.000
L30 Other dermatitis
0.814 0.186 0.000
L08 Other local infections of skin and subcutaneous tissue
0.813 0.187 0.000
L03 Cellulitis
0.813 0.187 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.812 0.188 0.000
F60-F69 Disorders of adult personality and behaviour
0.810 0.190 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.810 0.190 0.000
L98.8 Other specified disorders of skin and subcutaneous tissue
0.809 0.191 0.000
S05 Injury of eye and orbit
0.807 0.193 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.805 0.195 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.804 0.196 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.802 0.198 0.000
M25.7 Osteophyte
0.800 0.200 0.000
F10.2 Dependence syndrome
0.799 0.201 0.000
S01.8 Open wound of other parts of head
0.798 0.202 0.000
S22.30 Fracture of rib (closed)
0.796 0.204 0.000
S06 Intracranial injury
0.795 0.205 0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.794 0.206 0.000
Chapter VIII Diseases of the ear and mastoid process
0.788 0.212 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.786 0.214 0.000
S50 Superficial injury of forearm
0.785 0.215 0.000
H30-H36 Disorders of choroid and retina
0.784 0.216 0.000
L83 Acanthosis nigricans
0.784 0.216 0.000
L89 Decubitus ulcer
0.784 0.216 0.000
M10.99 Gout, unspecified (Site unspecified)
0.780 0.220 0.000
T92 Sequelae of injuries of upper limb
0.779 0.221 0.000
M79.9 Soft tissue disorder, unspecified
0.779 0.221 0.000
D61.9 Aplastic anaemia, unspecified
0.777 0.223 0.000
V40-V49 Car occupant injured in transport accident
0.777 0.223 0.000
M24 Other specific joint derangements
0.776 0.224 0.000
E50-E64 Other nutritional deficiencies
0.776 0.224 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.774 0.225 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.774 0.226 0.000
T51 Toxic effect of alcohol
0.774 0.226 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.773 0.227 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.773 0.227 0.000
L40-L45 Papulosquamous disorders
0.772 0.228 0.000
E21.3 Hyperparathyroidism, unspecified
0.772 0.228 0.000
S32.0 Fracture of lumbar vertebra
0.771 0.229 0.000
L91.0 Keloid scar
0.770 0.230 0.000
W00-W19 Falls
0.766 0.234 0.000
S51.0 Open wound of elbow
0.765 0.235 0.000
T98 Sequelae of other and unspecified effects of external causes
0.763 0.237 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.763 0.237 0.000
T40.6 Other and unspecified narcotics
0.763 0.237 0.000
H35 Other retinal disorders
0.763 0.237 0.000
E11.5 With peripheral circulatory complications
0.763 0.237 0.000
S56 Injury of muscle and tendon at forearm level
0.761 0.239 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.761 0.239 0.000
Y40 Systemic antibiotics
0.760 0.240 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.759 0.241 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.757 0.243 0.000
E11.8 With unspecified complications
0.756 0.244 0.000
D62 Acute posthaemorrhagic anaemia
0.756 0.244 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.756 0.244 0.000
M79.64 Pain in limb (Hand)
0.755 0.245 0.000
E23 Hypofunction and other disorders of pituitary gland
0.753 0.247 0.000
M60-M63 Disorders of muscles
0.752 0.248 0.000
L30.9 Dermatitis, unspecified
0.752 0.248 0.000
T39.1 4-Aminophenol derivatives
0.752 0.248 0.000
S27 Injury of other and unspecified intrathoracic organs
0.750 0.249 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.750 0.250 0.000
D80-D89 Certain disorders involving the immune mechanism
0.749 0.251 0.000
H35.8 Other specified retinal disorders
0.747 0.253 0.000
E29 Testicular dysfunction
0.746 0.254 0.000
Chapter XXII Codes for special purposes
0.746 0.254 0.000
M00-M03 Infectious arthropathies
0.746 0.254 0.000
E11.0 With coma
0.746 0.254 0.000
L03.1 Cellulitis of other parts of limb
0.745 0.255 0.000
M86-M90 Other osteopathies
0.744 0.256 0.000
W29 Contact with other powered hand tools and household machinery
0.743 0.257 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.743 0.257 0.000
T43.2 Other and unspecified antidepressants
0.742 0.258 0.000
R25 Abnormal involuntary movements
0.741 0.259 0.000
M72 Fibroblastic disorders
0.741 0.259 0.000
E27.9 Disorder of adrenal gland, unspecified
0.741 0.259 0.000
W50-W64 Exposure to animate mechanical forces
0.741 0.259 0.000
S01.2 Open wound of nose
0.740 0.260 0.000
S32.7 Multiple fractures of lumbar spine and pelvis
0.740 0.260 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.738 0.262 0.000
L08.8 Other specified local infections of skin and subcutaneous tissue
0.737 0.263 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.737 0.263 0.000
E27.1 Primary adrenocortical insufficiency
0.737 0.263 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.736 0.264 0.000
M25.78 Osteophyte (Other)
0.736 0.264 0.000
M79.2 Neuralgia and neuritis, unspecified
0.735 0.264 0.000
L91.8 Other hypertrophic disorders of skin
0.735 0.265 0.000
E21.0 Primary hyperparathyroidism
0.734 0.266 0.000
R25.2 Cramp and spasm
0.733 0.267 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.732 0.268 0.000
D55-D59 Haemolytic anaemias
0.732 0.268 0.000
M85 Other disorders of bone density and structure
0.732 0.268 0.000
M82 Osteoporosis in diseases classified elsewhere
0.731 0.269 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.730 0.270 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.730 0.270 0.000
D69 Purpura and other haemorrhagic conditions
0.730 0.270 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.730 0.270 0.000
L50 Urticaria
0.729 0.271 0.000
M21 Other acquired deformities of limbs
0.729 0.271 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.728 0.272 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.728 0.272 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.727 0.273 0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.726 0.274 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.726 0.274 0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis
0.725 0.275 0.000
H65-H75 Diseases of middle ear and mastoid
0.723 0.277 0.000
M79.62 Pain in limb (Upper arm)
0.723 0.277 0.000
T40.4 Other synthetic narcotics
0.722 0.278 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.722 0.278 0.000
E78.5 Hyperlipidaemia, unspecified
0.721 0.279 0.000
D61.1 Drug-induced aplastic anaemia
0.721 0.279 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.719 0.281 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
L10-L14 Bullous disorders
0.717 0.283 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.716 0.283 0.000
E22 Hyperfunction of pituitary gland
0.715 0.284 0.000
T86 Failure and rejection of transplanted organs and tissues
0.715 0.284 0.000
S06.0 Concussion
0.715 0.285 0.000
E34 Other endocrine disorders
0.714 0.286 0.000
L53 Other erythematous conditions
0.714 0.286 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.714 0.286 0.000
M25.77 Osteophyte (Ankle and foot)
0.713 0.287 0.000
S08 Traumatic amputation of part of head
0.713 0.287 0.000
S07 Crushing injury of head
0.713 0.287 0.000
S04 Injury of cranial nerves
0.713 0.287 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.713 0.287 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.713 0.287 0.000
F70-F79 Mental retardation
0.713 0.287 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.712 0.288 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.712 0.288 0.000
Y00-Y09 Assault
0.711 0.289 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.711 0.289 0.000
M79.3 Panniculitis, unspecified
0.711 0.289 0.000
S51.8 Open wound of other parts of forearm
0.711 0.289 0.000
L27 Dermatitis due to substances taken internally
0.710 0.290 0.000
M65-M68 Disorders of synovium and tendon
0.710 0.290 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.709 0.290 0.000
L94 Other localised connective tissue disorders
0.709 0.290 0.000
L93 Lupus erythematosus
0.709 0.290 0.000
L87 Transepidermal elimination disorders
0.709 0.290 0.000
L88 Pyoderma gangrenosum
0.709 0.290 0.000
L86 Keratoderma in diseases classified elsewhere
0.709 0.290 0.000
L80 Vitiligo
0.709 0.290 0.000
T40.2 Other opioids
0.709 0.291 0.000
E12 Malnutrition-related diabetes mellitus
0.709 0.291 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.709 0.291 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.709 0.291 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.709 0.291 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.709 0.291 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.709 0.291 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.709 0.291 0.000
F11 Mental and behavioural disorders due to use of opioids
0.709 0.291 0.000
T66-T78 Other and unspecified effects of external causes
0.708 0.292 0.000
S32.4 Fracture of acetabulum
0.707 0.293 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.707 0.293 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.707 0.293 0.000
M79.68 Pain in limb (Other)
0.707 0.293 0.000
M79.61 Pain in limb (Shoulder region)
0.707 0.293 0.000
D64 Other anaemias
0.707 0.293 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.706 0.294 0.000
T90 Sequelae of injuries of head
0.705 0.294 0.000
Y52.1 Calcium-channel blockers
0.705 0.295 0.000
L84 Corns and callosities
0.704 0.295 0.000
H55-H59 Other disorders of eye and adnexa
0.704 0.296 0.000
F30-F39 Mood [affective] disorders
0.704 0.296 0.000
T95 Sequelae of burns, corrosions and frostbite
0.703 0.297 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.703 0.297 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.703 0.297 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.703 0.297 0.000
T82.3 Mechanical complication of other vascular grafts
0.703 0.297 0.000
L04 Acute lymphadenitis
0.703 0.297 0.000
L01 Impetigo
0.703 0.297 0.000
L00 Staphylococcal scalded skin syndrome
0.703 0.297 0.000
T65 Toxic effect of other and unspecified substances
0.702 0.298 0.000
M35 Other systemic involvement of connective tissue
0.701 0.299 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.700 0.300 0.000
E26 Hyperaldosteronism
0.700 0.300 0.000
Y35-Y36 Legal intervention and operations of war
0.700 0.300 0.000
Y10-Y34 Event of undetermined intent
0.700 0.300 0.000
X85-X99 Assault
0.700 0.300 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.700 0.300 0.000
X30-X39 Exposure to forces of nature
0.700 0.300 0.000
X10-X19 Contact with heat and hot substances
0.700 0.300 0.000
X00-X09 Exposure to smoke, fire and flames
0.700 0.300 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.700 0.300 0.000
W75-W84 Other accidental threats to breathing
0.700 0.300 0.000
W65-W74 Accidental drowning and submersion
0.700 0.300 0.000
V98-V99 Other and unspecified transport accidents
0.700 0.300 0.000
V95-V97 Air and space transport accidents
0.700 0.300 0.000
V90-V94 Water transport accidents
0.700 0.300 0.000
V70-V79 Bus occupant injured in transport accident
0.700 0.300 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.700 0.300 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.700 0.300 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.700 0.300 0.000
V01-V09 Pedestrian injured in transport accident
0.700 0.300 0.000
L05 Pilonidal cyst
0.699 0.300 0.000
T81 Complications of procedures, not elsewhere classified
0.699 0.301 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.699 0.301 0.000
E32 Diseases of thymus
0.699 0.301 0.000
E31 Polyglandular dysfunction
0.699 0.301 0.000
E30 Disorders of puberty, not elsewhere classified
0.699 0.301 0.000
E25 Adrenogenital disorders
0.699 0.301 0.000
E24 Cushing's syndrome
0.699 0.301 0.000
E20 Hypoparathyroidism
0.699 0.301 0.000
F99 Mental disorder, not otherwise specified
0.698 0.302 0.000
E40-E46 Malnutrition
0.698 0.302 0.000
M91-M94 Chondropathies
0.697 0.302 0.000
E14.8 With unspecified complications
0.697 0.303 0.000
E14.7 With multiple complications
0.697 0.303 0.000
E14.6 With other specified complications
0.697 0.303 0.000
E14.5 With peripheral circulatory complications
0.697 0.303 0.000
E14.4 With neurological complications
0.697 0.303 0.000
E14.2 Withrenal complications
0.697 0.303 0.000
E14.1 With ketoacidosis
0.697 0.303 0.000
E14.0 With coma
0.697 0.303 0.000
M07 Psoriatic and enteropathic arthropathies
0.697 0.303 0.000
R47-R49 Symptoms and signs involving speech and voice
0.696 0.304 0.000
T51.0 Ethanol
0.696 0.304 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.694 0.306 0.000
S00.5 Superficial injury of lip and oral cavity
0.694 0.306 0.000
S00.4 Superficial injury of ear
0.694 0.306 0.000
M79.88 Other specified soft tissue disorders (Other)
0.693 0.307 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.693 0.307 0.000
M79.81 Other specified soft tissue disorders (Shoulder region)
0.693 0.307 0.000
M76 Enthesopathies of lower limb, excluding foot
0.693 0.307 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.693 0.307 0.000
L20 Atopic dermatitis
0.693 0.307 0.000
T39.0 Salicylates
0.693 0.307 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.693 0.307 0.000
E28 Ovarian dysfunction
0.693 0.307 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.692 0.308 0.000
S01.3 Open wound of ear
0.691 0.309 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.690 0.309 0.000
M11 Other crystal arthropathies
0.690 0.310 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.689 0.310 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.689 0.310 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.689 0.310 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.689 0.310 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.689 0.310 0.000
T36 Poisoning by systemic antibiotics
0.689 0.310 0.000
S00.7 Multiple superficial injuries of head
0.689 0.311 0.000
R25.1 Tremor, unspecified
0.689 0.311 0.000
M83 Adult osteomalacia
0.688 0.312 0.000
S32.00 Fracture of lumbar vertebra (closed)
0.687 0.313 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.687 0.313 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.687 0.313 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.686 0.314 0.000
F29 Unspecified nonorganic psychosis
0.685 0.315 0.000
F10.9 Unspecified mental and behavioural disorder
0.685 0.315 0.000
F10.8 Other mental and behavioural disorders
0.685 0.315 0.000
F10.7 Residual and late-onset psychotic disorder
0.685 0.315 0.000
F10.6 Amnesic syndrome
0.685 0.315 0.000
F10.5 Psychotic disorder
0.685 0.315 0.000
L92.0 Granuloma annulare
0.684 0.316 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.684 0.316 0.000
X50-X57 Overexertion, travel and privation
0.683 0.317 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.683 0.317 0.000
F17.9 Unspecified mental and behavioural disorder
0.682 0.318 0.000
F17.8 Other mental and behavioural disorders
0.682 0.318 0.000
F17.7 Residual and late-onset psychotic disorder
0.682 0.318 0.000
F17.6 Amnesic syndrome
0.682 0.318 0.000
F17.5 Psychotic disorder
0.682 0.318 0.000
F17.4 Withdrawal state with delirium
0.682 0.318 0.000
F17.3 Withdrawal state
0.682 0.318 0.000
F17.0 Acute intoxication
0.682 0.318 0.000
E11.7 With multiple complications
0.680 0.319 0.000
M40-M43 Deforming dorsopathies
0.680 0.320 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.679 0.321 0.000
V80-V89 Other land transport accidents
0.679 0.321 0.000
F10.4 Withdrawal state with delirium
0.678 0.322 0.000
S59 Other and unspecified injuries of forearm
0.678 0.322 0.000
S58 Traumatic amputation of forearm
0.678 0.322 0.000
S57 Crushing injury of forearm
0.678 0.322 0.000
S55 Injury of blood vessels at forearm level
0.678 0.322 0.000
S54 Injury of nerves at forearm level
0.678 0.322 0.000
F60 Specific personality disorders
0.677 0.323 0.000
M10.94 Gout, unspecified (Hand)
0.676 0.324 0.000
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.675 0.325 0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.675 0.325 0.000
M25.9 Joint disorder, unspecified
0.674 0.325 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.674 0.326 0.000
W23 Caught, crushed, jammed or pinched in or between objects
0.674 0.326 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.673 0.326 0.000
E83 Disorders of mineral metabolism
0.673 0.327 0.000
T79-T79 Certain early complications of trauma
0.673 0.327 0.000
Y57 Other and unspecified drugs and medicaments
0.671 0.328 0.000
S22.0 Fracture of thoracic vertebra
0.671 0.329 0.000
X20-X29 Contact with venomous animals and plants
0.671 0.329 0.000
S20 Superficial injury of thorax
0.671 0.329 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.670 0.330 0.000
S26 Injury of heart
0.670 0.330 0.000
S25 Injury of blood vessels of thorax
0.670 0.330 0.000
S24 Injury of nerves and spinal cord at thorax level
0.670 0.330 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.670 0.330 0.000
S21 Open wound of thorax
0.670 0.330 0.000
X60-X84 Intentional self-harm
0.669 0.330 0.000
Y59 Other and unspecified vaccines and biological substances
0.669 0.330 0.000
Y58 Bacterial vaccines
0.669 0.330 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.669 0.330 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.669 0.330 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.669 0.330 0.000
Y48 Anaesthetics and therapeutic gases
0.669 0.330 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.669 0.330 0.000
Y98 Lifestyle-related condition
0.669 0.330 0.000
Y97 Environmental-pollution-related condition
0.669 0.330 0.000
Y96 Work-related condition
0.669 0.330 0.000
M50-M54 Other dorsopathies
0.669 0.331 0.000
M13 Other arthritis
0.669 0.331 0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb
0.669 0.331 0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb
0.669 0.331 0.000
T93.4 Sequelae of injury of nerve of lower limb
0.669 0.331 0.000
T93.1 Sequelae of fracture of femur
0.669 0.331 0.000
T93.0 Sequelae of open wound of lower limb
0.669 0.331 0.000
S80-S89 Injuries to the knee and lower leg
0.669 0.331 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.669 0.331 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.669 0.331 0.000
S37 Injury of urinary and pelvic organs
0.669 0.331 0.000
S36 Injury of intra-abdominal organs
0.669 0.331 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.669 0.331 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.669 0.331 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.669 0.331 0.000
S31 Open wound of abdomen, lower back and pelvis
0.669 0.331 0.000
M84 Disorders of continuity of bone
0.668 0.332 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.668 0.332 0.000
V20-V29 Motorcycle rider injured in transport accident
0.667 0.333 0.000
W08 Fall involving other furniture
0.667 0.333 0.000
T91.1 Sequelae of fracture of spine
0.666 0.334 0.000
T23 Burn and corrosion of wrist and hand
0.666 0.334 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.665 0.335 0.000
M81.8 Other osteoporosis
0.665 0.335 0.000
M81.6 Localised osteoporosis [Lequesne]
0.665 0.335 0.000
M81.5 Idiopathic osteoporosis
0.665 0.335 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.665 0.335 0.000
M81.2 Osteoporosis of disuse
0.665 0.335 0.000
M81.1 Postoophorectomy osteoporosis
0.665 0.335 0.000
M81.0 Postmenopausal osteoporosis
0.665 0.335 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.665 0.335 0.000
T87 Complications peculiar to reattachment and amputation
0.663 0.337 0.000
F80-F89 Disorders of psychological development
0.663 0.337 0.000
M79.5 Residual foreign body in soft tissue
0.662 0.337 0.000
M14 Arthropathies in other diseases classified elsewhere
0.661 0.339 0.000
M12 Other specific arthropathies
0.661 0.339 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.661 0.339 0.000
M08 Juvenile arthritis
0.661 0.339 0.000
W29.9 Unspecified place
0.661 0.339 0.000
Y91.9 Alcohol involvement, not otherwise specified
0.660 0.340 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.660 0.340 0.000
M05 Seropositive rheumatoid arthritis
0.660 0.340 0.000
S10 Superficial injury of neck
0.659 0.341 0.000
L29 Pruritus
0.659 0.341 0.000
F22 Persistent delusional disorders
0.658 0.342 0.000
S06.00 Concussion (without open intracranial wound)
0.658 0.342 0.000
W25 Contact with sharp glass
0.658 0.342 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.657 0.343 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.657 0.343 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.656 0.344 0.000
T91.3 Sequelae of injury of spinal cord
0.655 0.345 0.000
L92.8 Other granulomatous disorders of skin and subcutaneous tissue
0.654 0.345 0.000
L92.2 Granuloma faciale [eosinophilic granuloma of skin]
0.654 0.345 0.000
L92.1 Necrobiosis lipoidica, not elsewhere classified
0.654 0.345 0.000
M79.1 Myalgia
0.654 0.346 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.654 0.346 0.000
Y40.0 Penicillins
0.654 0.346 0.000
E86 Volume depletion
0.654 0.346 0.000
Y44 Agents primarily affecting blood constituents
0.653 0.347 0.000
L25 Unspecified contact dermatitis
0.652 0.348 0.000
L24 Irritant contact dermatitis
0.652 0.348 0.000
L23 Allergic contact dermatitis
0.652 0.348 0.000
L21 Seborrhoeic dermatitis
0.652 0.348 0.000
L26 Exfoliative dermatitis
0.652 0.348 0.000
L22 Diaper [napkin] dermatitis
0.652 0.348 0.000
H34 Retinal vascular occlusions
0.652 0.348 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.651 0.349 0.000
M71 Other bursopathies
0.651 0.349 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.650 0.349 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.650 0.349 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.650 0.349 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.650 0.349 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.650 0.349 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.650 0.349 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.650 0.350 0.000
S32.3 Fracture of ilium
0.650 0.350 0.000
E11.6 With other specified complications
0.649 0.350 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.647 0.353 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.646 0.354 0.000
L03.8 Cellulitis of other sites
0.646 0.354 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.645 0.355 0.000
R49 Voice disturbances
0.645 0.355 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.645 0.355 0.000
M70.6 Trochanteric bursitis
0.645 0.355 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.645 0.355 0.000
L03.3 Cellulitis of trunk
0.645 0.355 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.644 0.356 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.644 0.356 0.000
T83.2 Mechanical complication of graft of urinary organ
0.644 0.356 0.000
S60-S69 Injuries to the wrist and hand
0.644 0.356 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.643 0.356 0.000
M77 Other enthesopathies
0.643 0.357 0.000
S09 Other and unspecified injuries of head
0.643 0.357 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.642 0.358 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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