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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75258359
log Bayes Factor = 8.02415
Chromosome 14   position 69,600,635  (GRCh37) Explore rs75258359 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E11 Non-insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E11.9 Without complications
0.999 0.001 0.000
E14 Unspecified diabetes mellitus
0.999 0.001 0.000
E14.9 Without complications
0.995 0.005 0.000
Chapter VI Diseases of the nervous system
0.993 0.007 0.000
E10 Insulin-dependent diabetes mellitus
0.992 0.008 0.000
G40-G47 Episodic and paroxysmal disorders
0.992 0.008 0.000
E11.3 With ophthalmic complications
0.983 0.017 0.000
E10.9 Without complications
0.982 0.018 0.000
G43 Migraine
0.979 0.021 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.977 0.023 0.000
G43.9 Migraine, unspecified
0.970 0.030 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.966 0.034 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.965 0.035 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.962 0.038 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.961 0.039 0.000
E14.3 With ophthalmic complications
0.950 0.050 0.000
E11.4 With neurological complications
0.946 0.054 0.000
E20-E35 Disorders of other endocrine glands
0.927 0.073 0.000
G62 Other polyneuropathies
0.924 0.076 0.000
# Top node
0.899 0.101 0.000
G90-G99 Other disorders of the nervous system
0.897 0.103 0.000
G56 Mononeuropathies of upper limb
0.876 0.124 0.000
E10.3 With ophthalmic complications
0.863 0.137 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.860 0.140 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.859 0.141 0.000
E11.2 With renal complications
0.857 0.143 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.853 0.147 0.000
G62.9 Polyneuropathy, unspecified
0.852 0.148 0.000
E11.6 With other specified complications
0.836 0.164 0.000
E11.5 With peripheral circulatory complications
0.836 0.164 0.000
E27 Other disorders of adrenal gland
0.834 0.166 0.000
G57 Mononeuropathies of lower limb
0.829 0.171 0.000
G62.8 Other specified polyneuropathies
0.827 0.173 0.000
G51 Facial nerve disorders
0.819 0.181 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.815 0.185 0.000
Chapter XX External causes of morbidity and mortality
0.809 0.191 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.809 0.191 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.807 0.193 0.000
M65-M68 Disorders of synovium and tendon
0.806 0.194 0.000
E40-E46 Malnutrition
0.802 0.198 0.000
M20-M25 Other joint disorders
0.800 0.200 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.781 0.218 0.000
E20 Hypoparathyroidism
0.781 0.219 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.775 0.225 0.000
G30-G32 Other degenerative diseases of the nervous system
0.773 0.227 0.000
E10.8 With unspecified complications
0.772 0.227 0.000
E11.1 With ketoacidosis
0.771 0.229 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.770 0.230 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.770 0.230 0.000
G41 Status epilepticus
0.763 0.237 0.000
D68 Other coagulation defects
0.763 0.237 0.000
M24 Other specific joint derangements
0.759 0.241 0.000
G95 Other diseases of spinal cord
0.757 0.243 0.000
G96 Other disorders of central nervous system
0.753 0.247 0.000
G54 Nerve root and plexus disorders
0.750 0.250 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.749 0.251 0.000
G45.4 Transient global amnesia
0.749 0.251 0.000
M65 Synovitis and tenosynovitis
0.749 0.251 0.000
G57.8 Other mononeuropathies of lower limb
0.746 0.254 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.743 0.256 0.000
G45.3 Amaurosis fugax
0.743 0.257 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.742 0.258 0.000
Chapter VII Diseases of the eye and adnexa
0.741 0.259 0.000
E50-E64 Other nutritional deficiencies
0.733 0.267 0.000
G43.1 Migraine with aura [classical migraine]
0.730 0.270 0.000
G20-G26 Extrapyramidal and movement disorders
0.728 0.272 0.000
D75 Other diseases of blood and blood-forming organs
0.727 0.273 0.000
E13 Other specified diabetes mellitus
0.727 0.273 0.000
G47 Sleep disorders
0.727 0.273 0.000
E10.2 With renal complications
0.727 0.273 0.000
H30-H36 Disorders of choroid and retina
0.727 0.273 0.000
M21 Other acquired deformities of limbs
0.725 0.275 0.000
E22 Hyperfunction of pituitary gland
0.724 0.275 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.723 0.277 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.722 0.278 0.000
E10.5 With peripheral circulatory complications
0.717 0.283 0.000
E11.8 With unspecified complications
0.717 0.283 0.000
E11.7 With multiple complications
0.717 0.283 0.000
E11.0 With coma
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E14.8 With unspecified complications
0.716 0.284 0.000
E14.7 With multiple complications
0.716 0.284 0.000
E14.6 With other specified complications
0.716 0.284 0.000
E14.5 With peripheral circulatory complications
0.716 0.284 0.000
E14.4 With neurological complications
0.716 0.284 0.000
E14.2 Withrenal complications
0.716 0.284 0.000
E14.1 With ketoacidosis
0.716 0.284 0.000
E14.0 With coma
0.716 0.284 0.000
H36 Retinal disorders in diseases classified elsewhere
0.716 0.284 0.000
G90 Disorders of autonomic nervous system
0.716 0.284 0.000
G56.0 Carpal tunnel syndrome
0.715 0.285 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.714 0.286 0.000
E00-E07 Disorders of thyroid gland
0.714 0.286 0.000
M86-M90 Other osteopathies
0.712 0.288 0.000
E10.7 With multiple complications
0.711 0.289 0.000
E10.6 With other specified complications
0.711 0.289 0.000
E10.0 With coma
0.711 0.289 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.711 0.289 0.000
H36.0 Diabetic retinopathy
0.710 0.290 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.709 0.291 0.000
G51.0 Bell's palsy
0.706 0.294 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.706 0.294 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.704 0.295 0.000
E28 Ovarian dysfunction
0.704 0.296 0.000
M05-M14 Inflammatory polyarthropathies
0.703 0.297 0.000
G43.8 Other migraine
0.702 0.298 0.000
G43.3 Complicated migraine
0.702 0.298 0.000
G43.2 Status migrainosus
0.702 0.298 0.000
G43.0 Migraine without aura [common migraine]
0.702 0.298 0.000
E29 Testicular dysfunction
0.701 0.299 0.000
G45.2 Multiple and bilateral precerebral artery syndromes
0.701 0.299 0.000
G45.1 Carotid artery syndrome (hemispheric)
0.701 0.299 0.000
G45.0 Vertebro-basilar artery syndrome
0.701 0.299 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.700 0.300 0.000
G61 Inflammatory polyneuropathy
0.700 0.300 0.000
H10-H13 Disorders of conjunctiva
0.700 0.300 0.000
G70-G73 Diseases of myoneural junction and muscle
0.699 0.301 0.000
M23 Internal derangement of knee
0.698 0.302 0.000
G56.8 Other mononeuropathies of upper limb
0.697 0.303 0.000
G59.0 Diabetic mononeuropathy
0.694 0.306 0.000
D73 Diseases of spleen
0.694 0.306 0.000
G52 Disorders of other cranial nerves
0.692 0.308 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.691 0.309 0.000
G60 Hereditary and idiopathic neuropathy
0.689 0.311 0.000
G64 Other disorders of peripheral nervous system
0.689 0.311 0.000
D70 Agranulocytosis
0.685 0.315 0.000
E46 Unspecified protein-energy malnutrition
0.684 0.316 0.000
E10.1 With ketoacidosis
0.679 0.321 0.000
M22 Disorders of patella
0.679 0.321 0.000
G30 Alzheimer's disease
0.678 0.322 0.000
Q23 Congenital malformations of aortic and mitral valves
0.678 0.322 0.000
E27.1 Primary adrenocortical insufficiency
0.677 0.323 0.000
E20.9 Hypoparathyroidism, unspecified
0.676 0.324 0.000
G56.2 Lesion of ulnar nerve
0.676 0.324 0.000
E24 Cushing's syndrome
0.672 0.328 0.000
G57.3 Lesion of lateral popliteal nerve
0.672 0.328 0.000
G56.3 Lesion of radial nerve
0.671 0.329 0.000
G56.1 Other lesions of median nerve
0.670 0.330 0.000
G95.9 Disease of spinal cord, unspecified
0.669 0.331 0.000
G93 Other disorders of brain
0.668 0.332 0.000
M80-M85 Disorders of bone density and structure
0.666 0.334 0.000
D68.8 Other specified coagulation defects
0.665 0.335 0.000
Q80-Q89 Other congenital malformations
0.665 0.335 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.665 0.335 0.000
E34 Other endocrine disorders
0.665 0.335 0.000
E32 Diseases of thymus
0.665 0.335 0.000
E31 Polyglandular dysfunction
0.665 0.335 0.000
E30 Disorders of puberty, not elsewhere classified
0.665 0.335 0.000
E25 Adrenogenital disorders
0.665 0.335 0.000
G44 Other headache syndromes
0.663 0.336 0.000
M24.0 Loose body in joint
0.662 0.337 0.000
G62.2 Polyneuropathy due to other toxic agents
0.662 0.338 0.000
G62.1 Alcoholic polyneuropathy
0.662 0.338 0.000
G62.0 Drug-induced polyneuropathy
0.662 0.338 0.000
G58 Other mononeuropathies
0.662 0.338 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.659 0.341 0.000
E26 Hyperaldosteronism
0.657 0.343 0.000
H35 Other retinal disorders
0.657 0.343 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.656 0.344 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.656 0.344 0.000
M00-M03 Infectious arthropathies
0.654 0.346 0.000
M67 Other disorders of synovium and tendon
0.654 0.346 0.000
G63.2 Diabetic polyneuropathy
0.653 0.347 0.000
M70-M79 Other soft tissue disorders
0.652 0.348 0.000
M65.8 Other synovitis and tenosynovitis
0.651 0.349 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.650 0.350 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.650 0.350 0.000
E23 Hypofunction and other disorders of pituitary gland
0.649 0.351 0.000
D75.2 Essential thrombocytosis
0.648 0.352 0.000
M40-M43 Deforming dorsopathies
0.646 0.354 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.645 0.355 0.000
W50-W64 Exposure to animate mechanical forces
0.644 0.356 0.000
M06 Other rheumatoid arthritis
0.643 0.357 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.643 0.357 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.643 0.357 0.000
G92 Toxic encephalopathy
0.643 0.357 0.000
D68.9 Coagulation defect, unspecified
0.642 0.358 0.000
M60-M63 Disorders of muscles
0.642 0.358 0.000
D68.5 Primary Thrombophilia
0.641 0.359 0.000
G37 Other demyelinating diseases of central nervous system
0.641 0.359 0.000
G47.9 Sleep disorder, unspecified
0.639 0.361 0.000
H11 Other disorders of conjunctiva
0.638 0.362 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.638 0.362 0.000
G82 Paraplegia and tetraplegia
0.636 0.364 0.000
Q28 Other congenital malformations of circulatory system
0.629 0.371 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.628 0.372 0.000
G56.4 Causalgia
0.628 0.372 0.000
D69 Purpura and other haemorrhagic conditions
0.625 0.375 0.000
M24.1 Other articular cartilage disorders
0.624 0.376 0.000
D75.1 Secondary polycythaemia
0.622 0.378 0.000
M23.3 Other meniscus derangements
0.622 0.378 0.000
G96.8 Other specified disorders of central nervous system
0.621 0.379 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.620 0.380 0.000
M21.6 Other acquired deformities of ankle and foot
0.618 0.382 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.616 0.384 0.000
Q35-Q37 Cleft lip and cleft palate
0.616 0.384 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.616 0.384 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.616 0.384 0.000
M86 Osteomyelitis
0.614 0.386 0.000
D68.6 Other Thrombophilia
0.614 0.386 0.000
G51.3 Clonic hemifacial spasm
0.614 0.386 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.612 0.388 0.000
Q23.1 Congenital insufficiency of aortic valve
0.612 0.388 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.610 0.390 0.000
Q00-Q07 Congenital malformations of the nervous system
0.610 0.390 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.607 0.393 0.000
H10 Conjunctivitis
0.605 0.395 0.000
G12 Spinal muscular atrophy and related syndromes
0.605 0.395 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.603 0.396 0.000
V80-V89 Other land transport accidents
0.603 0.397 0.000
Y43 Primarily systemic agents
0.603 0.397 0.000
D55-D59 Haemolytic anaemias
0.602 0.398 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.601 0.398 0.000
Q50-Q56 Congenital malformations of genital organs
0.601 0.399 0.000
Q18 Other congenital malformations of face and neck
0.601 0.399 0.000
M66 Spontaneous rupture of synovium and tendon
0.601 0.399 0.000
G47.8 Other sleep disorders
0.600 0.400 0.000
G41.9 Status epilepticus, unspecified
0.599 0.401 0.000
G57.1 Meralgia paraesthetica
0.599 0.401 0.000
G50 Disorders of trigeminal nerve
0.599 0.401 0.000
E27.5 Adrenomedullary hyperfunction
0.598 0.402 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.598 0.402 0.000
E27.2 Addisonian crisis
0.598 0.402 0.000
E27.0 Other adrenocortical overactivity
0.598 0.402 0.000
M23.4 Loose body in knee
0.598 0.402 0.000
H35.8 Other specified retinal disorders
0.598 0.402 0.000
G30.9 Alzheimer's disease, unspecified
0.598 0.402 0.000
X50-X57 Overexertion, travel and privation
0.596 0.404 0.000
G95.1 Vascular myelopathies
0.596 0.404 0.000
Y48 Anaesthetics and therapeutic gases
0.596 0.404 0.000
V40-V49 Car occupant injured in transport accident
0.595 0.405 0.000
E61 Deficiency of other nutrient elements
0.594 0.405 0.000
G57.9 Mononeuropathy of lower limb, unspecified
0.594 0.406 0.000
G57.5 Tarsal tunnel syndrome
0.594 0.406 0.000
G57.4 Lesion of medial popliteal nerve
0.594 0.406 0.000
G57.2 Lesion of femoral nerve
0.594 0.406 0.000
G57.0 Lesion of sciatic nerve
0.594 0.406 0.000
D80-D89 Certain disorders involving the immune mechanism
0.594 0.406 0.000
M31 Other necrotising vasculopathies
0.594 0.406 0.000
G54.9 Nerve root and plexus disorder, unspecified
0.592 0.408 0.000
E27.9 Disorder of adrenal gland, unspecified
0.591 0.409 0.000
D73.5 Infarction of spleen
0.589 0.411 0.000
M91-M94 Chondropathies
0.588 0.412 0.000
G96.0 Cerebrospinal fluid leak
0.588 0.412 0.000
G51.8 Other disorders of facial nerve
0.587 0.413 0.000
G51.4 Facial myokymia
0.587 0.413 0.000
G51.2 Melkersson's syndrome
0.587 0.413 0.000
G51.1 Geniculate ganglionitis
0.587 0.413 0.000
G93.0 Cerebral cysts
0.587 0.413 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.585 0.415 0.000
E27.8 Other specified disorders of adrenal gland
0.585 0.415 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.585 0.415 0.000
D74 Methaemoglobinaemia
0.585 0.415 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.585 0.415 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.585 0.415 0.000
M34 Systemic sclerosis
0.584 0.416 0.000
M24.07 Loose body in joint (Ankle and foot)
0.584 0.416 0.000
D60-D64 Aplastic and other anaemias
0.583 0.417 0.000
E07 Other disorders of thyroid
0.581 0.419 0.000
Y35-Y36 Legal intervention and operations of war
0.580 0.420 0.000
Y10-Y34 Event of undetermined intent
0.580 0.420 0.000
Y00-Y09 Assault
0.580 0.420 0.000
X85-X99 Assault
0.580 0.420 0.000
X30-X39 Exposure to forces of nature
0.580 0.420 0.000
X20-X29 Contact with venomous animals and plants
0.580 0.420 0.000
X10-X19 Contact with heat and hot substances
0.580 0.420 0.000
X00-X09 Exposure to smoke, fire and flames
0.580 0.420 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.580 0.420 0.000
W75-W84 Other accidental threats to breathing
0.580 0.420 0.000
W65-W74 Accidental drowning and submersion
0.580 0.420 0.000
V98-V99 Other and unspecified transport accidents
0.580 0.420 0.000
V95-V97 Air and space transport accidents
0.580 0.420 0.000
V90-V94 Water transport accidents
0.580 0.420 0.000
V70-V79 Bus occupant injured in transport accident
0.580 0.420 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.580 0.420 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.580 0.420 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.580 0.420 0.000
V01-V09 Pedestrian injured in transport accident
0.580 0.420 0.000
V20-V29 Motorcycle rider injured in transport accident
0.580 0.420 0.000
D67 Hereditary factor IX deficiency
0.580 0.420 0.000
D66 Hereditary factor VIII deficiency
0.580 0.420 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.580 0.420 0.000
G59.8 Other mononeuropathies in diseases classified elsewhere
0.579 0.421 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.578 0.422 0.000
G51.9 Disorder of facial nerve, unspecified
0.578 0.422 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.578 0.422 0.000
M06.9 Rheumatoid arthritis, unspecified
0.578 0.422 0.000
E22.0 Acromegaly and pituitary gigantism
0.576 0.424 0.000
M65.84 Other synovitis and tenosynovitis (Hand)
0.575 0.425 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.575 0.425 0.000
E45 Retarded development following protein-energy malnutrition
0.575 0.425 0.000
E43 Unspecified severe protein-energy malnutrition
0.575 0.425 0.000
E42 Marasmic kwashiorkor
0.575 0.425 0.000
E41 Nutritional marasmus
0.575 0.425 0.000
E40 Kwashiorkor
0.575 0.425 0.000
G90.3 Multisystem degeneration
0.574 0.425 0.000
M21.0 Valgus deformity, not elsewhere classified
0.574 0.426 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.574 0.426 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.573 0.427 0.000
M33 Dermatopolymyositis
0.573 0.427 0.000
M32 Systemic lupus erythematosus
0.573 0.427 0.000
M30 Polyarteritis nodosa and related conditions
0.573 0.427 0.000
M80 Osteoporosis with pathological fracture
0.572 0.428 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.571 0.429 0.000
M21.1 Varus deformity, not elsewhere classified
0.571 0.429 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.568 0.431 0.000
H35.3 Degeneration of macula and posterior pole
0.569 0.431 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.567 0.432 0.000
M12 Other specific arthropathies
0.564 0.436 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.564 0.436 0.000
Y45.1 Salicylates
0.563 0.437 0.000
M87 Osteonecrosis
0.562 0.438 0.000
M22.8 Other disorders of patella
0.562 0.438 0.000
G63.8 Polyneuropathy in other diseases classified elsewhere
0.560 0.440 0.000
G63.6 Polyneuropathy in other musculoskeletal disorders
0.560 0.440 0.000
G63.5 Polyneuropathy in systemic connective tissue disorders
0.560 0.440 0.000
G63.4 Polyneuropathy in nutritional deficiency
0.560 0.440 0.000
G63.3 Polyneuropathy in other endocrine and metabolic diseases
0.560 0.440 0.000
G63.1 Polyneuropathy in neoplastic disease
0.560 0.440 0.000
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere
0.560 0.440 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.560 0.440 0.000
E20.8 Other hypoparathyroidism
0.560 0.440 0.000
E20.1 Pseudohypoparathyroidism
0.560 0.440 0.000
E20.0 Idiopathic hypoparathyroidism
0.560 0.440 0.000
Q43 Other congenital malformations of intestine
0.558 0.442 0.000
G11 Hereditary ataxia
0.558 0.442 0.000
M14 Arthropathies in other diseases classified elsewhere
0.557 0.443 0.000
H31 Other disorders of choroid
0.556 0.444 0.000
G36 Other acute disseminated demyelination
0.555 0.444 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.554 0.446 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.554 0.446 0.000
E21.3 Hyperparathyroidism, unspecified
0.553 0.447 0.000
Q27 Other congenital malformations of peripheral vascular system
0.552 0.448 0.000
Q26 Congenital malformations of great veins
0.552 0.448 0.000
Q25 Congenital malformations of great arteries
0.552 0.448 0.000
Q24 Other congenital malformations of heart
0.552 0.448 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.552 0.448 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.552 0.448 0.000
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
0.552 0.448 0.000
G14 Postpolio syndrome
0.552 0.448 0.000
G10 Huntington's disease
0.552 0.448 0.000
D69.5 Secondary thrombocytopenia
0.551 0.449 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.550 0.450 0.000
X60-X84 Intentional self-harm
0.549 0.450 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.549 0.451 0.000
M84 Disorders of continuity of bone
0.548 0.452 0.000
G03 Meningitis due to other and unspecified causes
0.548 0.452 0.000
E16 Other disorders of pancreatic internal secretion
0.547 0.452 0.000
G41.8 Other status epilepticus
0.547 0.453 0.000
G41.2 Complex partial status epilepticus
0.547 0.453 0.000
G41.1 Petit mal status epilepticus
0.547 0.453 0.000
G41.0 Grand mal status epilepticus
0.547 0.453 0.000
D68.4 Acquired coagulation factor deficiency
0.547 0.453 0.000
D68.1 Hereditary factor XI deficiency
0.547 0.453 0.000
Q85 Phakomatoses, not elsewhere classified
0.547 0.453 0.000
M86.9 Osteomyelitis, unspecified
0.545 0.455 0.000
M23.0 Cystic meniscus
0.544 0.456 0.000
M24.9 Joint derangement, unspecified
0.544 0.456 0.000
M24.7 Protrusio acetabuli
0.544 0.456 0.000
M24.6 Ankylosis of joint
0.544 0.456 0.000
M24.5 Contracture of joint
0.544 0.456 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.544 0.456 0.000
M24.2 Disorder of ligament
0.544 0.456 0.000
G71 Primary disorders of muscles
0.544 0.456 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.543 0.457 0.000
G95.0 Syringomyelia and syringobulbia
0.543 0.457 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.542 0.458 0.000
G54.0 Brachial plexus disorders
0.542 0.458 0.000
Q76 Congenital malformations of spine and bony thorax
0.542 0.458 0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot
0.542 0.458 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.542 0.458 0.000
G82.5 Tetraplegia, unspecified
0.542 0.458 0.000
M22.3 Other derangements of patella
0.541 0.459 0.000
G95.8 Other specified diseases of spinal cord
0.541 0.459 0.000
G96.9 Disorder of central nervous system, unspecified
0.540 0.460 0.000
G96.1 Disorders of meninges, not elsewhere classified
0.540 0.460 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.540 0.460 0.000
E29.1 Testicular hypofunction
0.539 0.461 0.000
H11.9 Disorder of conjunctiva, unspecified
0.538 0.462 0.000
G25 Other extrapyramidal and movement disorders
0.538 0.462 0.000
G54.8 Other nerve root and plexus disorders
0.538 0.462 0.000
G54.7 Phantom limb syndrome without pain
0.538 0.462 0.000
G54.6 Phantom limb syndrome with pain
0.538 0.462 0.000
G54.5 Neuralgic amyotrophy
0.538 0.462 0.000
G54.4 Lumbosacral root disorders, not elsewhere classified
0.538 0.462 0.000
G54.3 Thoracic root disorders, not elsewhere classified
0.538 0.462 0.000
G54.2 Cervical root disorders, not elsewhere classified
0.538 0.462 0.000
G54.1 Lumbosacral plexus disorders
0.538 0.462 0.000
M21.2 Flexion deformity
0.537 0.463 0.000
E28.3 Primary ovarian failure
0.537 0.463 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.537 0.463 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.537 0.463 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.537 0.463 0.000
G00 Bacterial meningitis, not elsewhere classified
0.537 0.463 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.537 0.463 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.537 0.463 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.537 0.463 0.000
H10.9 Conjunctivitis, unspecified
0.537 0.463 0.000
E55 Vitamin D deficiency
0.537 0.463 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.537 0.463 0.000
G24 Dystonia
0.537 0.463 0.000
M65.2 Calcific tendinitis
0.537 0.463 0.000
M65.1 Other infective (teno)synovitis
0.537 0.463 0.000
M65.0 Abscess of tendon sheath
0.537 0.463 0.000
G83 Other paralytic syndromes
0.537 0.463 0.000
Q21 Congenital malformations of cardiac septa
0.537 0.463 0.000
G93.2 Benign intracranial hypertension
0.536 0.463 0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.536 0.464 0.000
H11.3 Conjunctival haemorrhage
0.535 0.465 0.000
M65.3 Trigger finger
0.535 0.465 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.534 0.465 0.000
M06.3 Rheumatoid nodule
0.534 0.466 0.000
M67.8 Other specified disorders of synovium and tendon
0.534 0.466 0.000
D72 Other disorders of white blood cells
0.533 0.467 0.000
G91 Hydrocephalus
0.532 0.468 0.000
H46 Optic neuritis
0.532 0.468 0.000
M23.1 Discoid meniscus (congenital)
0.532 0.468 0.000
Chapter I Certain infectious and parasitic diseases
0.532 0.468 0.000
Y45.5 4-Aminophenol derivatives
0.532 0.468 0.000
D73.0 Hyposplenism
0.532 0.468 0.000
W00-W19 Falls
0.532 0.468 0.000
E13.9 Without complications
0.531 0.469 0.000
V10-V19 Pedal cyclist injured in transport accident
0.529 0.470 0.000
M22.4 Chondromalacia patellae
0.529 0.471 0.000
Q28.2 Arteriovenous malformation of cerebral vessels
0.529 0.471 0.000
G90.2 Horner's syndrome
0.527 0.473 0.000
E22.1 Hyperprolactinaemia
0.527 0.473 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.526 0.474 0.000
M23.49 Loose body in knee-Unspec lig/men
0.526 0.474 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.526 0.474 0.000
E63 Other nutritional deficiencies
0.526 0.474 0.000
E56 Other vitamin deficiencies
0.526 0.474 0.000
E51 Thiamine deficiency
0.526 0.474 0.000
E50 Vitamin A deficiency
0.526 0.474 0.000
E60 Dietary zinc deficiency
0.526 0.474 0.000
E59 Dietary selenium deficiency
0.526 0.474 0.000
E58 Dietary calcium deficiency
0.526 0.474 0.000
E54 Ascorbic acid deficiency
0.526 0.474 0.000
E52 Niacin deficiency [pellagra]
0.526 0.474 0.000
H18 Other disorders of cornea
0.526 0.474 0.000
Y44 Agents primarily affecting blood constituents
0.524 0.476 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.523 0.477 0.000
W55 Bitten or struck by other mammals
0.522 0.478 0.000
G23 Other degenerative diseases of basal ganglia
0.522 0.478 0.000
G21 Secondary Parkinsonism
0.522 0.478 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.522 0.478 0.000
G22 Parkinsonism in diseases classified elsewhere
0.522 0.478 0.000
D75.9 Disease of blood and blood-forming organs, unspecified
0.521 0.479 0.000
D75.0 Familial erythrocytosis
0.521 0.479 0.000
E13.8 With unspecified complications
0.521 0.479 0.000
E13.7 With multiple complications
0.521 0.479 0.000
E13.6 With other specified complications
0.521 0.479 0.000
E13.5 With peripheral circulatory complications
0.521 0.479 0.000
E13.4 With neurological complications
0.521 0.479 0.000
E13.3 With ophthalmic complications
0.521 0.479 0.000
E13.2 With renal complications
0.521 0.479 0.000
E13.1 With ketoacidosis
0.521 0.479 0.000
E13.0 With coma
0.521 0.479 0.000
G47.4 Narcolepsy and cataplexy
0.521 0.479 0.000
G47.2 Disorders of the sleep-wake schedule
0.521 0.479 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.521 0.479 0.000
H30 Chorioretinal inflammation
0.521 0.479 0.000
D68.0 Von Willebrand's disease
0.520 0.480 0.000
G53.0 Postzoster neuralgia
0.520 0.480 0.000
M21.9 Acquired deformity of limb, unspecified
0.520 0.480 0.000
M21.8 Other specified acquired deformities of limbs
0.520 0.480 0.000
M21.7 Unequal limb length (acquired)
0.520 0.480 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.520 0.480 0.000
M21.4 Flat foot [pes planus] (acquired)
0.520 0.480 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.519 0.480 0.000
E22.8 Other hyperfunction of pituitary gland
0.519 0.480 0.000
M21.3 Wrist or foot drop (acquired)
0.519 0.481 0.000
E10.4 With neurological complications
0.519 0.481 0.000
W20-W49 Exposure to inanimate mechanical forces
0.519 0.481 0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances
0.519 0.481 0.000
G35 Multiple sclerosis
0.518 0.482 0.000
Y59 Other and unspecified vaccines and biological substances
0.518 0.482 0.000
Y58 Bacterial vaccines
0.518 0.482 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.518 0.482 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.518 0.482 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.518 0.482 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.518 0.482 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.518 0.482 0.000
G90.9 Disorder of autonomic nervous system, unspecified
0.518 0.482 0.000
E15 Nondiabetic hypoglycaemic coma
0.518 0.482 0.000
M11 Other crystal arthropathies
0.517 0.483 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.517 0.483 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.517 0.483 0.000
G30.0 Alzheimer's disease with early onset
0.515 0.485 0.000
G72 Other myopathies
0.515 0.485 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.514 0.486 0.000
E12.9 Without complications
0.514 0.486 0.000
E12.8 With unspecified complications
0.514 0.486 0.000
E12.7 With multiple complications
0.514 0.486 0.000
E12.6 With other specified complications
0.514 0.486 0.000
E12.5 With peripheral circulatory complications
0.514 0.486 0.000
E12.4 With neurological complications
0.514 0.486 0.000
E12.3 With ophthalmic complications
0.514 0.486 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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