TreeWAS – Variant ID: rs75296154

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
C50.9 Breast, unspecified	1.000	0.000
C50 Malignant neoplasm of breast	1.000	0.000
Z85.3 Personal history of malignant neoplasm of breast	1.000	0.000
C50.4 Upper-outer quadrant of breast	0.998	0.002
C50.2 Upper-inner quadrant of breast	0.970	0.030
C50-C50 Malignant neoplasm of breast	0.927	0.073
C50.3 Lower-inner quadrant of breast	0.925	0.075
C50.8 Overlapping lesion of breast	0.885	0.115
Chapter II Neoplasms	0.875	0.125
C50.1 Central portion of breast	0.862	0.138
D00-D09 In situ neoplasms	0.858	0.142
F10 Mental and behavioural disorders due to use of alcohol	0.854	0.146
F10.2 Dependence syndrome	0.848	0.152
D05 Carcinoma in situ of breast	0.835	0.165
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.834	0.166
F10.3 Withdrawal state	0.825	0.175
Chapter V Mental and behavioural disorders	0.825	0.175
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.818	0.182
F10.1 Harmful use	0.816	0.184
# Top node	0.815	0.185
Chapter VIII Diseases of the ear and mastoid process	0.801	0.199
D05.1 Intraductal carcinoma in situ	0.798	0.202
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.794	0.206
D03 Melanoma in situ	0.792	0.208
C50.5 Lower-outer quadrant of breast	0.775	0.225
H90-H95 Other disorders of ear	0.770	0.230
C50.0 Nipple and areola	0.765	0.234
H90 Conductive and sensorineural hearing loss	0.760	0.240
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.760	0.240
F30-F39 Mood [affective] disorders	0.758	0.242
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.754	0.246
H90.3 Sensorineural hearing loss, bilateral	0.741	0.259
C77.3 Axillary and upper limb lymph nodes	0.741	0.259
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.740	0.260
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.740	0.260
D03.3 Melanoma in situ of other and unspecified parts of face	0.730	0.270
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.728	0.272
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.722	0.278
D05.9 Carcinoma in situ of breast, unspecified	0.721	0.279
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.719	0.281
C50.6 Axillary tail of breast	0.717	0.283
S50-S59 Injuries to the elbow and forearm	0.714	0.286
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.711	0.289
Chapter XII Diseases of the skin and subcutaneous tissue	0.704	0.296
Chapter I Certain infectious and parasitic diseases	0.703	0.297
S40-S49 Injuries to the shoulder and upper arm	0.703	0.297
F31 Bipolar affective disorder	0.701	0.299
C78.7 Secondary malignant neoplasm of liver	0.692	0.308
T88 Other complications of surgical and medical care, not elsewhere classified	0.685	0.315
S10-S19 Injuries to the neck	0.680	0.320
S52 Fracture of forearm	0.675	0.325
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.674	0.326
D03.6 Melanoma in situ of upper limb, including shoulder	0.667	0.333
S42 Fracture of shoulder and upper arm	0.667	0.333
H60-H62 Diseases of external ear	0.665	0.335
Chapter VII Diseases of the eye and adnexa	0.663	0.337
T36-T50 Poisoning by drugs, medicaments and biological substances	0.657	0.343
L50-L54 Urticaria and erythema	0.653	0.346
H90.5 Sensorineural hearing loss, unspecified	0.652	0.348
T84.0 Mechanical complication of internal joint prosthesis	0.651	0.349
F80-F89 Disorders of psychological development	0.647	0.353
F10.4 Withdrawal state with delirium	0.645	0.355
H65-H75 Diseases of middle ear and mastoid	0.645	0.355
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.644	0.356
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.638	0.362
L80-L99 Other disorders of the skin and subcutaneous tissue	0.638	0.362
S52.1 Fracture of upper end of radius	0.637	0.363
H80-H83 Diseases of inner ear	0.627	0.373
C40-C41 Malignant neoplasms of bone and articular cartilage	0.627	0.373
D07 Carcinoma in situ of other and unspecified genital organs	0.627	0.373
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.625	0.375
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.622	0.378
F34 Persistent mood [affective] disorders	0.621	0.378
D09 Carcinoma in situ of other and unspecified sites	0.621	0.379
S52.0 Fracture of upper end of ulna	0.621	0.379
L89 Decubitus ulcer	0.621	0.379
D05.0 Lobular carcinoma in situ	0.620	0.380
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.618	0.381
F31.9 Bipolar affective disorder, unspecified	0.615	0.385
D02 Carcinoma in situ of middle ear and respiratory system	0.615	0.385
D01 Carcinoma in situ of other and unspecified digestive organs	0.615	0.385
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.615	0.385
L50 Urticaria	0.615	0.385
F33 Recurrent depressive disorder	0.613	0.387
F10.9 Unspecified mental and behavioural disorder	0.612	0.388
F10.8 Other mental and behavioural disorders	0.612	0.388
F10.7 Residual and late-onset psychotic disorder	0.612	0.388
F10.6 Amnesic syndrome	0.612	0.388
F10.5 Psychotic disorder	0.612	0.388
S52.10 Fracture of upper end of radius (closed)	0.610	0.390
F30 Manic episode	0.609	0.391
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.608	0.392
F11 Mental and behavioural disorders due to use of opioids	0.608	0.392
Q60-Q64 Congenital malformations of the urinary system	0.608	0.392
C71 Malignant neoplasm of brain	0.606	0.394
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.603	0.397
T84.2 Mechanical complication of internal fixation device of other bones	0.600	0.400
B15-B19 Viral hepatitis	0.600	0.400
B25-B34 Other viral diseases	0.599	0.401
D05.7 Other carcinoma in situ of breast	0.599	0.401
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.598	0.402
F18 Mental and behavioural disorders due to use of volatile solvents	0.598	0.402
F16 Mental and behavioural disorders due to use of hallucinogens	0.598	0.402
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.598	0.402
F14 Mental and behavioural disorders due to use of cocaine	0.598	0.402
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.598	0.402
F12 Mental and behavioural disorders due to use of cannabinoids	0.598	0.402
C64-C68 Malignant neoplasms of urinary tract	0.592	0.408
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.591	0.409
F70-F79 Mental retardation	0.591	0.409
H90.2 Conductive hearing loss, unspecified	0.591	0.409
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.591	0.409
S42.0 Fracture of clavicle	0.589	0.411
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.589	0.411
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.588	0.412
C76 Malignant neoplasm of other and ill-defined sites	0.587	0.413
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.585	0.415
Chapter XVI Certain conditions originating in the perinatal period	0.584	0.416
S52.00 Fracture of upper end of ulna (closed)	0.583	0.417
H10-H13 Disorders of conjunctiva	0.582	0.418
C02 Malignant neoplasm of other and unspecified parts of tongue	0.582	0.418
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.582	0.418
D37-D48 Neoplasms of uncertain or unknown behaviour	0.581	0.419
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.580	0.420
F60-F69 Disorders of adult personality and behaviour	0.580	0.420
H92 Otalgia and effusion of ear	0.579	0.421
L89.2 Stage III decubitus ulcer	0.575	0.425
C78.2 Secondary malignant neoplasm of pleura	0.572	0.428
S90-S99 Injuries to the ankle and foot	0.572	0.428
S20-S29 Injuries to the thorax	0.571	0.429
F00-F09 Organic, including symptomatic, mental disorders	0.570	0.430
T33-T35 Frostbite	0.569	0.431
T26-T28 Burns and corrosions confined to eye and internal organs	0.569	0.431
T20-T25 Burns and corrosions of external body surface, specified by site	0.569	0.431
T00-T07 Injuries involving multiple body regions	0.569	0.431
Chapter XX External causes of morbidity and mortality	0.569	0.431
B07 Viral warts	0.568	0.432
D03.9 Melanoma in situ, unspecified	0.568	0.432
D03.8 Melanoma in situ of other sites	0.568	0.432
D03.4 Melanoma in situ of scalp and neck	0.568	0.432
D03.2 Melanoma in situ of ear and external auricular canal	0.568	0.432
D03.1 Melanoma in situ of eyelid, including canthus	0.568	0.432
D03.0 Melanoma in situ of lip	0.568	0.432
S80-S89 Injuries to the knee and lower leg	0.567	0.432
T88.4 Failed or difficult intubation	0.567	0.433
C77.8 Lymph nodes of multiple regions	0.566	0.434
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.566	0.434
S70-S79 Injuries to the hip and thigh	0.566	0.434
H46-H48 Disorders of optic nerve and visual pathways	0.563	0.437
T15-T19 Effects of foreign body entering through natural orifice	0.563	0.437
C80 Malignant neoplasm without specification of site	0.561	0.439
C79 Secondary malignant neoplasm of other sites	0.561	0.439
L40-L45 Papulosquamous disorders	0.558	0.442
D03.5 Melanoma in situ of trunk	0.557	0.442
S42.1 Fracture of scapula	0.557	0.443
C78.1 Secondary malignant neoplasm of mediastinum	0.556	0.444
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.552	0.448
H94 Other disorders of ear in diseases classified elsewhere	0.552	0.448
L50.0 Allergic urticaria	0.551	0.449
T87 Complications peculiar to reattachment and amputation	0.550	0.450
C69 Malignant neoplasm of eye and adnexa	0.550	0.450
B20-B24 Human immunodeficiency virus [HIV] disease	0.550	0.450
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.549	0.451
T80 Complications following infusion, transfusion and therapeutic injection	0.549	0.451
C49 Malignant neoplasm of other connective and soft tissue	0.547	0.453
S41 Open wound of shoulder and upper arm	0.545	0.454
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.545	0.455
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.545	0.455
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.545	0.455
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.545	0.455
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.545	0.455
H90.0 Conductive hearing loss, bilateral	0.545	0.455
H81 Disorders of vestibular function	0.545	0.455
H72 Perforation of tympanic membrane	0.544	0.455
S19 Other and unspecified injuries of neck	0.544	0.456
F38 Other mood [affective] disorders	0.544	0.456
F39 Unspecified mood [affective] disorder	0.544	0.456
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.542	0.458
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.541	0.459
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.541	0.459
T84.3 Mechanical complication of other bone devices, implants and grafts	0.541	0.459
H25-H28 Disorders of lens	0.539	0.461
H61 Other disorders of external ear	0.538	0.462
L52 Erythema nodosum	0.538	0.462
L50.9 Urticaria, unspecified	0.538	0.462
H11 Other disorders of conjunctiva	0.537	0.463
B25 Cytomegaloviral disease	0.535	0.465
S42.00 Fracture of clavicle (closed)	0.534	0.466
D04 Carcinoma in situ of skin	0.532	0.468
L92 Granulomatous disorders of skin and subcutaneous tissue	0.532	0.468
L89.0 Stage I decubitus ulcer and pressure area	0.531	0.469
S11 Open wound of neck	0.531	0.469
S32 Fracture of lumbar spine and pelvis	0.530	0.470
T79-T79 Certain early complications of trauma	0.530	0.470
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.529	0.471
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.528	0.472
S42.3 Fracture of shaft of humerus	0.528	0.472
S52.3 Fracture of shaft of radius	0.528	0.472
L81 Other disorders of pigmentation	0.528	0.472
B35-B49 Mycoses	0.528	0.472
F33.1 Recurrent depressive disorder, current episode moderate	0.527	0.473
Q00-Q07 Congenital malformations of the nervous system	0.525	0.475
C10 Malignant neoplasm of oropharynx	0.525	0.475
F34.1 Dysthymia	0.523	0.477
T86 Failure and rejection of transplanted organs and tissues	0.523	0.477
C77.0 Lymph nodes of head, face and neck	0.522	0.478
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.522	0.478
C70 Malignant neoplasm of meninges	0.522	0.478
H60 Otitis externa	0.521	0.479
C71.2 Temporal lobe	0.521	0.479
C09 Malignant neoplasm of tonsil	0.520	0.479
Q61 Cystic kidney disease	0.520	0.480
F81 Specific developmental disorders of scholastic skills	0.520	0.480
L97 Ulcer of lower limb, not elsewhere classified	0.520	0.480
S42.7 Multiple fractures of clavicle, scapula and humerus	0.519	0.481
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.519	0.481
C78.4 Secondary malignant neoplasm of small intestine	0.518	0.482
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.518	0.482
L89.1 Stage II decubitus ulcer	0.518	0.482
A80-A89 Viral infections of the central nervous system	0.516	0.484
B18 Chronic viral hepatitis	0.516	0.484
F99-F99 Unspecified mental disorder	0.515	0.484
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.515	0.485
Q35-Q37 Cleft lip and cleft palate	0.515	0.485
Q30-Q34 Congenital malformations of the respiratory system	0.515	0.485
H53-H54 Visual disturbances and blindness	0.514	0.486
S50 Superficial injury of forearm	0.514	0.486
Chapter XXII Codes for special purposes	0.514	0.486
S42.9 Fracture of shoulder girdle, part unspecified	0.514	0.486
T88.5 Other complications of anaesthesia	0.514	0.486
S59 Other and unspecified injuries of forearm	0.512	0.488
S58 Traumatic amputation of forearm	0.512	0.488
S57 Crushing injury of forearm	0.512	0.488
S56 Injury of muscle and tendon at forearm level	0.512	0.488
S55 Injury of blood vessels at forearm level	0.512	0.488
S54 Injury of nerves at forearm level	0.512	0.488
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.512	0.488
S12 Fracture of neck	0.511	0.488
H50 Other strabismus	0.511	0.489
H71 Cholesteatoma of middle ear	0.511	0.489
Q38-Q45 Other congenital malformations of the digestive system	0.510	0.489
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.510	0.490
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.510	0.490
C13 Malignant neoplasm of hypopharynx	0.510	0.490
C11 Malignant neoplasm of nasopharynx	0.510	0.490
C08 Malignant neoplasm of other and unspecified major salivary glands	0.510	0.490
C06 Malignant neoplasm of other and unspecified parts of mouth	0.510	0.490
C05 Malignant neoplasm of palate	0.510	0.490
C04 Malignant neoplasm of floor of mouth	0.510	0.490
C03 Malignant neoplasm of gum	0.510	0.490
C00 Malignant neoplasm of lip	0.510	0.490
C12 Malignant neoplasm of pyriform sinus	0.510	0.490
C07 Malignant neoplasm of parotid gland	0.510	0.490
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.509	0.491
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.509	0.491
L20-L30 Dermatitis and eczema	0.508	0.492
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.507	0.493
H52 Disorders of refraction and accommodation	0.507	0.493
A30-A49 Other bacterial diseases	0.506	0.494
S10 Superficial injury of neck	0.506	0.494
T84.1 Mechanical complication of internal fixation device of bones of limb	0.506	0.494
L10-L14 Bullous disorders	0.505	0.495
L84 Corns and callosities	0.504	0.495
B99-B99 Other infectious diseases	0.504	0.496
B85-B89 Pediculosis, acariasis and other infestations	0.504	0.496
B50-B64 Protozoal diseases	0.504	0.496
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.504	0.496
A75-A79 Rickettsioses	0.504	0.496
A70-A74 Other diseases caused by chlamydiae	0.504	0.496
A65-A69 Other spirochaetal diseases	0.504	0.496
A20-A28 Certain zoonotic bacterial diseases	0.504	0.496
A15-A19 Tuberculosis	0.504	0.496
S48 Traumatic amputation of shoulder and upper arm	0.504	0.496
S45 Injury of blood vessels at shoulder and upper arm level	0.504	0.496
S44 Injury of nerves at shoulder and upper arm level	0.504	0.496
S47 Crushing injury of shoulder and upper arm	0.504	0.496
H11.9 Disorder of conjunctiva, unspecified	0.503	0.497
C01 Malignant neoplasm of base of tongue	0.503	0.497
F31.8 Other bipolar affective disorders	0.503	0.497
F31.7 Bipolar affective disorder, currently in remission	0.503	0.497
F31.6 Bipolar affective disorder, current episode mixed	0.503	0.497
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.503	0.497
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.503	0.497
C79.9 Secondary malignant neoplasm, unspecified site	0.502	0.498
D03.7 Melanoma in situ of lower limb, including hip	0.501	0.498
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.501	0.499
F17 Mental and behavioural disorders due to use of tobacco	0.501	0.499
F29 Unspecified nonorganic psychosis	0.499	0.501
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.498	0.502
H93 Other disorders of ear, not elsewhere classified	0.498	0.502
D46 Myelodysplastic syndromes	0.497	0.503
S81 Open wound of lower leg	0.496	0.504
H81.0 Meniere's disease	0.496	0.504
L51 Erythema multiforme	0.496	0.504
Q50-Q56 Congenital malformations of genital organs	0.495	0.505
F31.0 Bipolar affective disorder, current episode hypomanic	0.493	0.507
T88.9 Complication of surgical and medical care, unspecified	0.491	0.509
T88.3 Malignant hyperthermia due to anaesthesis	0.491	0.509
T88.2 Shock due to anaesthesia	0.491	0.509
T88.1 Other complications following immunisation, not elsewhere classified	0.491	0.509
T88.0 Infection following immunisation	0.491	0.509
H49 Paralytic strabismus	0.491	0.509
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.489	0.511
B25.9 Cytomegaloviral disease, unspecified	0.489	0.511
B27 Infectious mononucleosis	0.489	0.511
C15-C26 Malignant neoplasms of digestive organs	0.488	0.512
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.488	0.512
S17 Crushing injury of neck	0.487	0.513
S15 Injury of blood vessels at neck level	0.487	0.513
S14 Injury of nerves and spinal cord at neck level	0.487	0.513
S18 Traumatic amputation at neck level	0.487	0.513
S16 Injury of muscle and tendon at neck level	0.487	0.513
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.487	0.513
Q80-Q89 Other congenital malformations	0.487	0.513
F30.9 Manic episode, unspecified	0.487	0.513
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.486	0.513
S42.4 Fracture of lower end of humerus	0.486	0.514
B65-B83 Helminthiases	0.486	0.514
T46 Poisoning by agents primarily affecting the cardiovascular system	0.484	0.516
S52.9 Fracture of forearm, part unspecified	0.484	0.516
S52.8 Fracture of other parts of forearm	0.484	0.516
S52.7 Multiple fractures of forearm	0.484	0.516
S52.4 Fracture of shafts of both ulna and radius	0.484	0.516
S52.2 Fracture of shaft of ulna	0.484	0.516
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.483	0.517
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system	0.483	0.517
C46 Kaposi's sarcoma	0.483	0.517
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.482	0.517
H46 Optic neuritis	0.483	0.517
S36 Injury of intra-abdominal organs	0.481	0.519
Q65 Congenital deformities of hip	0.481	0.519
C97 Malignant neoplasms of independent (primary) multiple sites	0.479	0.520
S42.10 Fracture of scapula (closed)	0.479	0.521
H69 Other disorders of Eustachian tube	0.479	0.521
S42.8 Fracture of other parts of shoulder and upper arm	0.478	0.522
T81 Complications of procedures, not elsewhere classified	0.478	0.522
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.477	0.522
Q20-Q28 Congenital malformations of the circulatory system	0.477	0.523
H62 Disorders of external ear in diseases classified elsewhere	0.477	0.523
V20-V29 Motorcycle rider injured in transport accident	0.477	0.523
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.475	0.525
D06 Carcinoma in situ of cervix uteri	0.474	0.526
B90-B94 Sequelae of infectious and parasitic diseases	0.473	0.526
F20 Schizophrenia	0.473	0.527
A50-A64 Infections with a predominantly sexual mode of transmission	0.472	0.528
H70 Mastoiditis and related conditions	0.472	0.528
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.472	0.528
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.471	0.529
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.471	0.529
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.471	0.529
T41 Poisoning by anaesthetics and therapeutic gases	0.471	0.529
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.471	0.529
T36 Poisoning by systemic antibiotics	0.471	0.529
H66 Suppurative and unspecified otitis media	0.471	0.529
C02.9 Tongue, unspecified	0.471	0.529
T66-T78 Other and unspecified effects of external causes	0.470	0.530
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.469	0.531
L54 Erythema in diseases classified elsewhere	0.469	0.531
L43 Lichen planus	0.469	0.531
S49 Other and unspecified injuries of shoulder and upper arm	0.468	0.532
Chapter VI Diseases of the nervous system	0.466	0.534
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.465	0.535
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.465	0.535
S40 Superficial injury of shoulder and upper arm	0.464	0.536
W20-W49 Exposure to inanimate mechanical forces	0.464	0.536
F84 Pervasive developmental disorders	0.464	0.536
F80 Specific developmental disorders of speech and language	0.464	0.536
F89 Unspecified disorder of psychological development	0.464	0.536
F88 Other disorders of psychological development	0.464	0.536
F83 Mixed specific developmental disorders	0.464	0.536
F82 Specific developmental disorder of motor function	0.464	0.536
S46 Injury of muscle and tendon at shoulder and upper arm level	0.464	0.536
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.463	0.537
H68 Eustachian salpingitis and obstruction	0.463	0.537
H67 Otitis media in diseases classified elsewhere	0.463	0.537
L91 Hypertrophic disorders of skin	0.462	0.537
Q66 Congenital deformities of feet	0.462	0.538
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.462	0.538
H52.0 Hypermetropia	0.461	0.539
D07.5 Prostate	0.459	0.541
H55-H59 Other disorders of eye and adnexa	0.458	0.542
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.458	0.542
L94 Other localised connective tissue disorders	0.458	0.542
L93 Lupus erythematosus	0.458	0.542
L87 Transepidermal elimination disorders	0.458	0.542
L88 Pyoderma gangrenosum	0.458	0.542
L86 Keratoderma in diseases classified elsewhere	0.458	0.542
L80 Vitiligo	0.458	0.542
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.458	0.542
S37 Injury of urinary and pelvic organs	0.458	0.542
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.458	0.542
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.458	0.542
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.458	0.542
S31 Open wound of abdomen, lower back and pelvis	0.458	0.542
F30.0 Hypomania	0.458	0.542
B00 Herpesviral [herpes simplex] infections	0.457	0.542
S52.11 Fracture of upper end of radius (open)	0.457	0.543
C45 Mesothelioma	0.457	0.543
Q12 Congenital lens malformations	0.457	0.543
L95 Vasculitis limited to skin, not elsewhere classified	0.456	0.544
L89.9 Decubitus ulcer and pressure area, unspecified	0.454	0.546
C71.3 Parietal lobe	0.453	0.547
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.453	0.547
Q76 Congenital malformations of spine and bony thorax	0.453	0.547
H74 Other disorders of middle ear and mastoid	0.453	0.547
X60-X84 Intentional self-harm	0.453	0.547
T51 Toxic effect of alcohol	0.453	0.547
H60.1 Cellulitis of external ear	0.452	0.548
D09.0 Bladder	0.452	0.548
Q63 Other congenital malformations of kidney	0.452	0.548
D07.1 Vulva	0.451	0.548
H82 Vertiginous syndromes in diseases classified elsewhere	0.450	0.550
C42 hematopoietic and reticuloendothelial systems (ICD-O-3 specific)	0.450	0.550
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites	0.450	0.550
C40 Malignant neoplasm of bone and articular cartilage of limbs	0.450	0.550
D07.6 Other and unspecified male genital organs	0.449	0.551
D07.4 Penis	0.449	0.551
D07.3 Other and unspecified female genital organs	0.449	0.551
D07.2 Vagina	0.449	0.551
D07.0 Endometrium	0.449	0.551
B18.2 Chronic viral hepatitis C	0.449	0.551
S32.0 Fracture of lumbar vertebra	0.449	0.551
T81.4 Infection following a procedure, not elsewhere classified	0.449	0.551
F25 Schizoaffective disorders	0.448	0.551
F28 Other nonorganic psychotic disorders	0.448	0.551
F24 Induced delusional disorder	0.448	0.551
F21 Schizotypal disorder	0.448	0.551
C49.0 Connective and soft tissue of head, face and neck	0.447	0.553
S19.9 Unspecified injury of neck	0.447	0.553
F11.2 Dependence syndrome	0.446	0.554
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.446	0.554
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified	0.446	0.554
B06 Rubella [German measles]	0.446	0.554
B05 Measles	0.446	0.554
B01 Varicella [chickenpox]	0.446	0.554
B09 Unspecified viral infection characterised by skin and mucous membrane lesions	0.446	0.554
B04 Monkeypox	0.446	0.554
B03 Smallpox	0.446	0.554
F34.9 Persistent mood [affective] disorder, unspecified	0.446	0.554
F34.8 Other persistent mood [affective] disorders	0.446	0.554
F34.0 Cyclothymia	0.446	0.554
D09.9 Carcinoma in situ, unspecified	0.446	0.554
D09.7 Carcinoma in situ of other specified sites	0.446	0.554
D09.3 Thyroid and other endocrine glands	0.446	0.554
D09.2 Eye	0.446	0.554
D09.1 Other and unspecified urinary organs	0.446	0.554
S91 Open wound of ankle and foot	0.446	0.554
H25 Senile cataract	0.446	0.554
S52.01 Fracture of upper end of ulna (open)	0.445	0.554
L89.3 Stage IV decubitus ulcer	0.445	0.555
C02.1 Border of tongue	0.445	0.555
L81.4 Other melanin hyperpigmentation	0.444	0.556
C75 Malignant neoplasm of other endocrine glands and related structures	0.443	0.556
C74 Malignant neoplasm of adrenal gland	0.443	0.556
H72.0 Central perforation of tympanic membrane	0.443	0.557
Q61.0 Congenital single renal cyst	0.442	0.558
B17 Other acute viral hepatitis	0.442	0.558
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.442	0.558
S27 Injury of other and unspecified intrathoracic organs	0.442	0.558
G90-G99 Other disorders of the nervous system	0.442	0.558
C79.2 Secondary malignant neoplasm of skin	0.442	0.558
T16 Foreign body in ear	0.441	0.559
D00.2 Stomach	0.441	0.559
D00.1 Oesophagus	0.441	0.559
D00.0 Lip, oral cavity and pharynx	0.441	0.559
D01.9 Digestive organ, unspecified	0.441	0.559
D01.7 Other specified digestive organs	0.441	0.559
D01.5 Liver, gallbladder and bile ducts	0.441	0.559
D01.4 Other and unspecified parts of intestine	0.441	0.559
D01.3 Anus and anal canal	0.441	0.559
D01.2 Rectum	0.441	0.559
D01.1 Rectosigmoid junction	0.441	0.559
D01.0 Colon	0.441	0.559
D02.4 Respiratory system, unspecified	0.441	0.559
D02.3 Other parts of respiratory system	0.441	0.559
D02.2 Bronchus and lung	0.441	0.559
D02.1 Trachea	0.441	0.559
D02.0 Larynx	0.441	0.559
L50.8 Other urticaria	0.441	0.559
L50.6 Contact urticaria	0.441	0.559
L50.5 Cholinergic urticaria	0.441	0.559
L50.4 Vibratory urticaria	0.441	0.559
L50.3 Dermatographic urticaria	0.441	0.559
L50.2 Urticaria due to cold and heat	0.441	0.559
L50.1 Idiopathic urticaria	0.441	0.559
F01 Vascular dementia	0.440	0.560
F33.8 Other recurrent depressive disorders	0.440	0.560
F33.4 Recurrent depressive disorder, currently in remission	0.440	0.560
F33.0 Recurrent depressive disorder, current episode mild	0.440	0.560
B24 Unspecified human immunodeficiency virus [HIV] disease	0.440	0.560
B15 Acute hepatitis A	0.438	0.561
T13 Other injuries of lower limb, level unspecified	0.438	0.562
D46.9 Myelodysplastic syndrome, unspecified	0.437	0.563
X20-X29 Contact with venomous animals and plants	0.437	0.563
F30.8 Other manic episodes	0.437	0.563
F30.2 Mania with psychotic symptoms	0.437	0.563
F30.1 Mania without psychotic symptoms	0.437	0.563
C71.1 Frontal lobe	0.436	0.564
C69.9 Eye, unspecified	0.436	0.564
H51 Other disorders of binocular movement	0.436	0.564

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations