TreeWAS – Variant ID: rs753057

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
M20-M25 Other joint disorders	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
S00-S09 Injuries to the head	1.000	0.000
M23 Internal derangement of knee	0.999	0.001
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.999	0.001
M23.3 Other meniscus derangements	0.999	0.001
S00 Superficial injury of head	0.999	0.001
# Top node	0.999	0.001
M24 Other specific joint derangements	0.995	0.005
S00.8 Superficial injury of other parts of head	0.990	0.010
Chapter XII Diseases of the skin and subcutaneous tissue	0.987	0.013
S60-S69 Injuries to the wrist and hand	0.987	0.013
M23.30 Other meniscus derangements (Multiple sites)	0.987	0.013
M22 Disorders of patella	0.972	0.028
L50-L54 Urticaria and erythema	0.971	0.029
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.962	0.038
S80-S89 Injuries to the knee and lower leg	0.959	0.041
Chapter XX External causes of morbidity and mortality	0.956	0.044
M22.4 Chondromalacia patellae	0.955	0.045
S70-S79 Injuries to the hip and thigh	0.952	0.048
S00.1 Contusion of eyelid and periocular area	0.950	0.050
M24.1 Other articular cartilage disorders	0.944	0.056
S09 Other and unspecified injuries of head	0.942	0.058
M91-M94 Chondropathies	0.934	0.066
L50 Urticaria	0.920	0.080
L20-L30 Dermatitis and eczema	0.920	0.080
S66 Injury of muscle and tendon at wrist and hand level	0.909	0.091
M31 Other necrotising vasculopathies	0.903	0.097
S09.9 Unspecified injury of head	0.901	0.099
S60 Superficial injury of wrist and hand	0.901	0.099
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.898	0.102
M24.0 Loose body in joint	0.893	0.107
M24.8 Other specific joint derangements, not elsewhere classified	0.892	0.108
M40-M43 Deforming dorsopathies	0.890	0.110
L53 Other erythematous conditions	0.889	0.111
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.889	0.111
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.887	0.113
M86-M90 Other osteopathies	0.885	0.114
M94 Other disorders of cartilage	0.884	0.116
M65-M68 Disorders of synovium and tendon	0.877	0.123
Q00-Q07 Congenital malformations of the nervous system	0.875	0.125
L50.9 Urticaria, unspecified	0.874	0.126
S64 Injury of nerves at wrist and hand level	0.872	0.128
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.869	0.131
S69 Other and unspecified injuries of wrist and hand	0.862	0.138
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.855	0.145
S10-S19 Injuries to the neck	0.851	0.149
W00-W19 Falls	0.850	0.150
Chapter VII Diseases of the eye and adnexa	0.850	0.150
M94.8 Other specified disorders of cartilage	0.848	0.152
S72 Fracture of femur	0.848	0.152
S00.2 Other superficial injuries of eyelid and periocular area	0.847	0.153
S00.9 Superficial injury of head, part unspecified	0.847	0.153
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.842	0.158
M80-M85 Disorders of bone density and structure	0.842	0.158
S89 Other and unspecified injuries of lower leg	0.841	0.159
M21 Other acquired deformities of limbs	0.836	0.164
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.834	0.166
M35 Other systemic involvement of connective tissue	0.832	0.168
S65 Injury of blood vessels at wrist and hand level	0.829	0.171
L40-L45 Papulosquamous disorders	0.829	0.171
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.828	0.172
W20-W49 Exposure to inanimate mechanical forces	0.825	0.175
M31.6 Other giant cell arteritis	0.824	0.176
L53.9 Erythematous condition, unspecified	0.824	0.176
M24.16 Other articular cartilage disorders (Lower leg)	0.821	0.179
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.818	0.182
M94.88 Other specified disorders of cartilage (Other)	0.815	0.185
Q05 Spina bifida	0.813	0.187
L30 Other dermatitis	0.812	0.188
L27 Dermatitis due to substances taken internally	0.810	0.190
M23.6 Other spontaneous disruption of ligament(s) of knee	0.806	0.194
S05 Injury of eye and orbit	0.804	0.196
M41 Scoliosis	0.802	0.198
M24.13 Other articular cartilage disorders (Forearm)	0.799	0.201
S70 Superficial injury of hip and thigh	0.796	0.204
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.796	0.204
M24.2 Disorder of ligament	0.793	0.207
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.792	0.208
Q76 Congenital malformations of spine and bony thorax	0.792	0.208
V10-V19 Pedal cyclist injured in transport accident	0.791	0.208
S50-S59 Injuries to the elbow and forearm	0.790	0.210
T20-T25 Burns and corrosions of external body surface, specified by site	0.788	0.212
T00-T07 Injuries involving multiple body regions	0.785	0.215
Q80-Q89 Other congenital malformations	0.783	0.217
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.782	0.218
S64.0 Injury of ulnar nerve at wrist and hand level	0.781	0.219
H10-H13 Disorders of conjunctiva	0.781	0.219
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.781	0.219
T15-T19 Effects of foreign body entering through natural orifice	0.780	0.220
H46-H48 Disorders of optic nerve and visual pathways	0.778	0.222
S76 Injury of muscle and tendon at hip and thigh level	0.778	0.222
Chapter XV Pregnancy, childbirth and the puerperium	0.777	0.223
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.775	0.225
M24.07 Loose body in joint (Ankle and foot)	0.773	0.227
S60.9 Superficial injury of wrist and hand, unspecified	0.773	0.227
S80 Superficial injury of lower leg	0.773	0.227
S69.9 Unspecified injury of wrist and hand	0.772	0.228
S60.8 Other superficial injuries of wrist and hand	0.771	0.229
Q05.9 Spina bifida, unspecified	0.768	0.232
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.766	0.234
X60-X84 Intentional self-harm	0.765	0.235
M24.6 Ankylosis of joint	0.763	0.237
M23.5 Chronic instability of knee	0.762	0.238
S90-S99 Injuries to the ankle and foot	0.760	0.240
Y57 Other and unspecified drugs and medicaments	0.760	0.240
M24.11 Other articular cartilage disorders (Shoulder region)	0.759	0.241
Chapter IV Endocrine, nutritional and metabolic diseases	0.757	0.243
M35.0 Sicca syndrome [Sjogren]	0.757	0.243
S89.9 Unspecified injury of lower leg	0.757	0.243
Chapter VI Diseases of the nervous system	0.757	0.243
M23.8 Other internal derangements of knee	0.757	0.243
M24.5 Contracture of joint	0.755	0.245
S00.7 Multiple superficial injuries of head	0.755	0.245
W19 Unspecified fall	0.751	0.249
L51 Erythema multiforme	0.750	0.250
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.749	0.251
H43-H45 Disorders of vitreous body and globe	0.748	0.252
T66-T78 Other and unspecified effects of external causes	0.745	0.255
W29 Contact with other powered hand tools and household machinery	0.745	0.255
L00-L08 Infections of the skin and subcutaneous tissue	0.745	0.255
O00-O08 Pregnancy with abortive outcome	0.744	0.256
T79-T79 Certain early complications of trauma	0.741	0.259
M24.02 Loose body in joint (Upper arm)	0.739	0.261
E20-E35 Disorders of other endocrine glands	0.739	0.261
M41.9 Scoliosis, unspecified	0.738	0.262
M89 Other disorders of bone	0.738	0.262
M30 Polyarteritis nodosa and related conditions	0.738	0.262
S71 Open wound of hip and thigh	0.737	0.263
S02 Fracture of skull and facial bones	0.736	0.264
L30.9 Dermatitis, unspecified	0.734	0.266
S81 Open wound of lower leg	0.734	0.266
S72.0 Fracture of neck of femur	0.733	0.267
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.732	0.268
S82 Fracture of lower leg, including ankle	0.732	0.268
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.731	0.269
S00.5 Superficial injury of lip and oral cavity	0.730	0.270
Chapter VIII Diseases of the ear and mastoid process	0.725	0.275
L27.0 Generalised skin eruption due to drugs and medicaments	0.723	0.277
S01 Open wound of head	0.722	0.278
L50.0 Allergic urticaria	0.721	0.279
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.717	0.283
M33 Dermatopolymyositis	0.717	0.283
M32 Systemic lupus erythematosus	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
H10 Conjunctivitis	0.717	0.283
S08 Traumatic amputation of part of head	0.717	0.283
S07 Crushing injury of head	0.717	0.283
S04 Injury of cranial nerves	0.717	0.283
S03 Dislocation, sprain and strain of joints and ligaments of head	0.717	0.283
M23.9 Internal derangement of knee, unspecified	0.717	0.283
M23.1 Discoid meniscus (congenital)	0.717	0.283
M23.0 Cystic meniscus	0.717	0.283
M23.37 Other meniscus derangements-Capsular lig	0.716	0.284
S00.4 Superficial injury of ear	0.716	0.284
Chapter XVI Certain conditions originating in the perinatal period	0.716	0.284
X40-X49 Accidental poisoning by and exposure to noxious substances	0.716	0.284
S72.1 Pertrochanteric fracture	0.715	0.285
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.714	0.286
M24.9 Joint derangement, unspecified	0.713	0.287
M24.7 Protrusio acetabuli	0.713	0.287
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.713	0.287
W15 Fall from cliff	0.712	0.288
G00-G09 Inflammatory diseases of the central nervous system	0.712	0.288
W19.9 Unspecified place	0.711	0.289
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.711	0.289
O85-O92 Complications predominantly related to the puerperium	0.711	0.289
Q20-Q28 Congenital malformations of the circulatory system	0.711	0.289
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.710	0.290
Q65 Congenital deformities of hip	0.709	0.291
L10-L14 Bullous disorders	0.708	0.292
Y00-Y09 Assault	0.707	0.293
L02 Cutaneous abscess, furuncle and carbuncle	0.706	0.294
M65 Synovitis and tenosynovitis	0.706	0.294
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.704	0.296
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.704	0.296
M00-M03 Infectious arthropathies	0.703	0.297
M81 Osteoporosis without pathological fracture	0.702	0.298
L40 Psoriasis	0.701	0.299
M60-M63 Disorders of muscles	0.700	0.299
M67 Other disorders of synovium and tendon	0.700	0.300
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.700	0.300
M66 Spontaneous rupture of synovium and tendon	0.700	0.300
W10 Fall on and from stairs and steps	0.700	0.300
Q76.0 Spina bifida occulta	0.699	0.301
M24.4 Recurrent dislocation and subluxation of joint	0.698	0.302
M22.1 Recurrent subluxation of patella	0.697	0.303
M22.9 Disorder of patella, unspecified	0.697	0.303
M22.3 Other derangements of patella	0.697	0.303
M22.0 Recurrent dislocation of patella	0.697	0.303
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.697	0.303
L54 Erythema in diseases classified elsewhere	0.696	0.304
L52 Erythema nodosum	0.696	0.304
H47 Other disorders of optic [2nd] nerve and visual pathways	0.695	0.305
M90 Osteopathies in diseases classified elsewhere	0.694	0.305
L20 Atopic dermatitis	0.694	0.305
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.692	0.308
S64.3 Injury of digital nerve of thumb	0.690	0.310
S65.0 Injury of ulnar artery at wrist and hand level	0.690	0.310
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.690	0.310
Q35-Q37 Cleft lip and cleft palate	0.690	0.310
Q30-Q34 Congenital malformations of the respiratory system	0.690	0.310
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.689	0.311
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.688	0.312
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.688	0.312
S88 Traumatic amputation of lower leg	0.688	0.312
S87 Crushing injury of lower leg	0.688	0.312
S85 Injury of blood vessels at lower leg level	0.688	0.312
S84 Injury of nerves at lower leg level	0.688	0.312
W29.9 Unspecified place	0.688	0.312
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.687	0.313
M93 Other osteochondropathies	0.687	0.313
M87 Osteonecrosis	0.686	0.314
Y35-Y36 Legal intervention and operations of war	0.685	0.314
Y10-Y34 Event of undetermined intent	0.685	0.314
X85-X99 Assault	0.685	0.314
X30-X39 Exposure to forces of nature	0.685	0.314
X10-X19 Contact with heat and hot substances	0.685	0.314
X00-X09 Exposure to smoke, fire and flames	0.685	0.314
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.685	0.314
W75-W84 Other accidental threats to breathing	0.685	0.314
W65-W74 Accidental drowning and submersion	0.685	0.314
V98-V99 Other and unspecified transport accidents	0.685	0.314
V95-V97 Air and space transport accidents	0.685	0.314
V90-V94 Water transport accidents	0.685	0.314
V70-V79 Bus occupant injured in transport accident	0.685	0.314
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.685	0.314
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.685	0.314
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.685	0.314
V01-V09 Pedestrian injured in transport accident	0.685	0.314
M21.2 Flexion deformity	0.684	0.316
L29 Pruritus	0.683	0.317
S78 Traumatic amputation of hip and thigh	0.683	0.317
S77 Crushing injury of hip and thigh	0.683	0.317
S75 Injury of blood vessels at hip and thigh level	0.683	0.317
S74 Injury of nerves at hip and thigh level	0.683	0.317
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.683	0.317
M41.94 Scoliosis, unspecified (Thoracic region)	0.683	0.317
Y57.9 Drug or medicament, unspecified	0.682	0.318
X58-X59 Accidental exposure to other and unspecified factors	0.681	0.319
M24.17 Other articular cartilage disorders (Ankle and foot)	0.680	0.320
W50-W64 Exposure to animate mechanical forces	0.678	0.322
O02 Other abnormal products of conception	0.678	0.322
M31.3 Wegener's granulomatosis	0.678	0.322
M23.4 Loose body in knee	0.678	0.322
M24.19 Other articular cartilage disorders (Site unspecified)	0.677	0.323
M24.18 Other articular cartilage disorders (Other)	0.677	0.323
M24.14 Other articular cartilage disorders (Hand)	0.677	0.323
M24.12 Other articular cartilage disorders (Upper arm)	0.677	0.323
M24.10 Other articular cartilage disorders (Multiple sites)	0.677	0.323
H55-H59 Other disorders of eye and adnexa	0.677	0.323
Y44 Agents primarily affecting blood constituents	0.676	0.324
M22.8 Other disorders of patella	0.676	0.324
S00.3 Superficial injury of nose	0.676	0.324
S09.8 Other specified injuries of head	0.676	0.324
S09.7 Multiple injuries of head	0.676	0.324
S09.2 Traumatic rupture of ear drum	0.676	0.324
S09.1 Injury of muscle and tendon of head	0.676	0.324
S09.0 Injury of blood vessels of head, not elsewhere classified	0.676	0.324
V80-V89 Other land transport accidents	0.675	0.325
S67 Crushing injury of wrist and hand	0.675	0.325
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.674	0.326
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.674	0.326
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.674	0.326
X50-X57 Overexertion, travel and privation	0.673	0.326
H53-H54 Visual disturbances and blindness	0.673	0.327
S80.8 Other superficial injuries of lower leg	0.673	0.327
M21.6 Other acquired deformities of ankle and foot	0.672	0.327
M22.2 Patellofemoral disorders	0.671	0.329
H10.9 Conjunctivitis, unspecified	0.671	0.329
Q67.5 Congenital deformity of spine	0.671	0.329
M88 Paget's disease of bone [osteitis deformans]	0.671	0.329
S62 Fracture at wrist and hand level	0.671	0.329
M92 Other juvenile osteochondrosis	0.670	0.330
M91 Juvenile osteochondrosis of hip and pelvis	0.670	0.330
M85 Other disorders of bone density and structure	0.669	0.330
M84 Disorders of continuity of bone	0.668	0.332
Y40 Systemic antibiotics	0.668	0.332
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.667	0.333
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.667	0.333
M43 Other deforming dorsopathies	0.667	0.333
L53.8 Other specified erythematous conditions	0.666	0.334
M94.86 Other specified disorders of cartilage (Lower leg)	0.666	0.334
S86 Injury of muscle and tendon at lower leg level	0.666	0.334
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.665	0.335
S56 Injury of muscle and tendon at forearm level	0.665	0.335
S82.4 Fracture of fibula alone	0.664	0.336
W44 Foreign body entering into or through eye or natural orifice	0.662	0.338
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.662	0.338
S60.2 Contusion of other parts of wrist and hand	0.661	0.338
L50.8 Other urticaria	0.660	0.340
L50.6 Contact urticaria	0.660	0.340
L50.5 Cholinergic urticaria	0.660	0.340
L50.4 Vibratory urticaria	0.660	0.340
L50.3 Dermatographic urticaria	0.660	0.340
L50.2 Urticaria due to cold and heat	0.660	0.340
L50.1 Idiopathic urticaria	0.660	0.340
L25 Unspecified contact dermatitis	0.660	0.340
L24 Irritant contact dermatitis	0.660	0.340
L23 Allergic contact dermatitis	0.660	0.340
L21 Seborrhoeic dermatitis	0.660	0.340
L26 Exfoliative dermatitis	0.660	0.340
L22 Diaper [napkin] dermatitis	0.660	0.340
S12 Fracture of neck	0.658	0.342
S79 Other and unspecified injuries of hip and thigh	0.657	0.343
M24.27 Disorder of ligament (Ankle and foot)	0.655	0.345
V40-V49 Car occupant injured in transport accident	0.654	0.346
S76.4 Injury of other and unspecified muscles and tendons at thigh level	0.653	0.347
O03 Spontaneous abortion	0.653	0.347
Y48 Anaesthetics and therapeutic gases	0.653	0.347
G70-G73 Diseases of myoneural junction and muscle	0.652	0.348
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.652	0.348
S66.8 Injury of other muscles and tendons at wrist and hand level	0.652	0.348
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.652	0.348
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.652	0.348
M25 Other joint disorders, not elsewhere classified	0.651	0.349
S72.00 Fracture of neck of femur (closed)	0.651	0.349
V18 Pedal cyclist injured in noncollision transport accident	0.651	0.349
S83.6 Sprain and strain of other and unspecified parts of knee	0.650	0.350
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.649	0.351
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.648	0.352
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.648	0.352
S00.0 Superficial injury of scalp	0.648	0.352
M31.9 Necrotising vasculopathy, unspecified	0.647	0.352
M31.8 Other specified necrotising vasculopathies	0.647	0.352
M31.7 Microscopic polyangiitis	0.647	0.352
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.647	0.352
M31.4 Aortic arch syndrome [Takayasu]	0.647	0.352
M31.2 Lethal midline granuloma	0.647	0.352
M31.1 Thrombotic microangiopathy	0.647	0.352
M31.0 Hypersensitivity angiitis	0.647	0.352
S19 Other and unspecified injuries of neck	0.646	0.353
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.646	0.354
S60.7 Multiple superficial injuries of wrist and hand	0.646	0.354
S60.1 Contusion of finger(s) with damage to nail	0.646	0.354
S60.0 Contusion of finger(s) without damage to nail	0.646	0.354
M89.9 Disorder of bone, unspecified	0.646	0.354
Q78 Other osteochondrodysplasias	0.644	0.356
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.644	0.356
Q75 Other congenital malformations of skull and face bones	0.644	0.356
Q74 Other congenital malformations of limb(s)	0.644	0.356
Q73 Reduction defects of unspecified limb	0.644	0.356
Q72 Reduction defects of lower limb	0.644	0.356
Q71 Reduction defects of upper limb	0.644	0.356
Q70 Syndactyly	0.644	0.356
Q69 Polydactyly	0.644	0.356
Q68 Other congenital musculoskeletal deformities	0.644	0.356
M23.2 Derangement of meniscus due to old tear or injury	0.644	0.356
E27 Other disorders of adrenal gland	0.643	0.357
H46 Optic neuritis	0.643	0.357
G80-G83 Cerebral palsy and other paralytic syndromes	0.643	0.357
M65.9 Synovitis and tenosynovitis, unspecified	0.643	0.357
X20-X29 Contact with venomous animals and plants	0.642	0.358
Y53 Agents primarily affecting the gastro-intestinal system	0.641	0.359
T14 Injury of unspecified body region	0.641	0.359
M24.09 Loose body in joint (Site unspecified)	0.640	0.360
M24.08 Loose body in joint (Other)	0.640	0.360
M24.06 Loose body in joint-Lower leg	0.640	0.360
M24.05 Loose body in joint (Pelvic region and thigh)	0.640	0.360
M24.04 Loose body in joint (Hand)	0.640	0.360
M24.03 Loose body in joint (Forearm)	0.640	0.360
M24.01 Loose body in joint (Shoulder region)	0.640	0.360
M24.00 Loose body in joint (Multiple sites)	0.640	0.360
S70.9 Superficial injury of hip and thigh, unspecified	0.640	0.360
H43 Disorders of vitreous body	0.639	0.361
O02.1 Missed abortion	0.639	0.361
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.639	0.361
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.639	0.361
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.639	0.361
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.639	0.361
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.639	0.361
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.639	0.361
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.639	0.361
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.639	0.361
S65.5 Injury of blood vessel(s) of other finger	0.639	0.361
O86 Other puerperal infections	0.639	0.361
M42 Spinal osteochondrosis	0.638	0.362
M40 Kyphosis and lordosis	0.638	0.362
L53.3 Other chronic figurate erythema	0.638	0.362
L53.2 Erythema marginatum	0.638	0.362
L53.1 Erythema annulare centrifugum	0.638	0.362
L53.0 Toxic erythema	0.638	0.362
G90-G99 Other disorders of the nervous system	0.637	0.363
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.635	0.365
S50 Superficial injury of forearm	0.635	0.365
S02.1 Fracture of base of skull	0.634	0.365
M21.1 Varus deformity, not elsewhere classified	0.634	0.365
M94.2 Chondromalacia	0.634	0.366
M94.9 Disorder of cartilage, unspecified	0.634	0.366
M94.3 Chondrolysis	0.634	0.366
M94.1 Relapsing polychondritis	0.634	0.366
M94.0 Chondrocostal junction syndrome [Tietze]	0.634	0.366
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.634	0.366
Q66 Congenital deformities of feet	0.633	0.367
W18 Other fall on same level	0.633	0.367
L40.0 Psoriasis vulgaris	0.632	0.368
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.629	0.371
T00 Superficial injuries involving multiple body regions	0.629	0.371
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.628	0.371
Q07 Other congenital malformations of nervous system	0.627	0.373
Q06 Other congenital malformations of spinal cord	0.627	0.373
Q04 Other congenital malformations of brain	0.627	0.373
Q03 Congenital hydrocephalus	0.627	0.373
Q01 Encephalocele	0.627	0.373
Q00 Anencephaly and similar malformations	0.627	0.373
Q02 Microcephaly	0.627	0.373
M34 Systemic sclerosis	0.626	0.374
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.625	0.374
S64.9 Injury of unspecified nerve at wrist and hand level	0.625	0.375
S64.8 Injury of other nerves at wrist and hand level	0.625	0.375
S64.7 Injury of multiple nerves at wrist and hand level	0.625	0.375
S64.2 Injury of radial nerve at wrist and hand level	0.625	0.375
S64.1 Injury of median nerve at wrist and hand level	0.625	0.375
M82 Osteoporosis in diseases classified elsewhere	0.624	0.376
L43 Lichen planus	0.623	0.377
Y59 Other and unspecified vaccines and biological substances	0.623	0.377
Y58 Bacterial vaccines	0.623	0.377
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.623	0.377
Y50 Central nervous system stimulants, not elsewhere classified	0.623	0.377
Y49 Psychotropic drugs, not elsewhere classified	0.623	0.377
Y47 Sedatives, hypnotics and antianxiety drugs	0.623	0.377
Y46 Antiepileptics and anti-Parkinsonism drugs	0.623	0.377
S83.2 Tear of meniscus, current	0.623	0.377
S81.8 Open wound of other parts of lower leg	0.621	0.378
G04 Encephalitis, myelitis and encephalomyelitis	0.621	0.379
S40-S49 Injuries to the shoulder and upper arm	0.621	0.379
Chapter XXII Codes for special purposes	0.621	0.379
L60-L75 Disorders of skin appendages	0.620	0.380
V20-V29 Motorcycle rider injured in transport accident	0.620	0.380
S70.8 Other superficial injuries of hip and thigh	0.620	0.380
S72.10 Pertrochanteric fracture (closed)	0.620	0.380
M86 Osteomyelitis	0.619	0.381
S30 Superficial injury of abdomen, lower back and pelvis	0.618	0.381
S69.8 Other specified injuries of wrist and hand	0.618	0.382
S69.7 Multiple injuries of wrist and hand	0.618	0.382
E23 Hypofunction and other disorders of pituitary gland	0.617	0.383
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.617	0.383
Y79 Orthopaedic devices associated with adverse incidents	0.616	0.383
S32 Fracture of lumbar spine and pelvis	0.616	0.384
T78 Adverse effects, not elsewhere classified	0.616	0.384
S01.1 Open wound of eyelid and periocular area	0.616	0.384
S01.8 Open wound of other parts of head	0.616	0.384
S13.4 Sprain and strain of cervical spine	0.616	0.384
Y45.1 Salicylates	0.616	0.384
S82.40 Fracture of fibula alone (closed)	0.616	0.384
S20-S29 Injuries to the thorax	0.613	0.386
W08 Fall involving other furniture	0.613	0.387
W15.8 Other specified place	0.613	0.387
E28 Ovarian dysfunction	0.613	0.387
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.612	0.388
S06 Intracranial injury	0.612	0.388
H90-H95 Other disorders of ear	0.612	0.388
H47.3 Other disorders of optic disk	0.611	0.389
S14 Injury of nerves and spinal cord at neck level	0.611	0.389
D60-D64 Aplastic and other anaemias	0.611	0.389
S62.3 Fracture of other metacarpal bone	0.611	0.389
O04 Medical abortion	0.611	0.389
S17 Crushing injury of neck	0.610	0.389
S15 Injury of blood vessels at neck level	0.610	0.389
S11 Open wound of neck	0.610	0.389
S18 Traumatic amputation at neck level	0.610	0.389
S16 Injury of muscle and tendon at neck level	0.610	0.389
H11 Other disorders of conjunctiva	0.610	0.390
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.610	0.390
W16 Diving or jumping into water causing injury other than drowning or submersion	0.609	0.391
W14 Fall from tree	0.609	0.391
W12 Fall on and from scaffolding	0.609	0.391
W11 Fall on and from ladder	0.609	0.391
W09 Fall involving playground equipment	0.609	0.391
W05 Fall involving wheelchair	0.609	0.391
W04 Fall while being carried or supported by other persons	0.609	0.391
W03 Other fall on same level due to collision with, or pushing by, another person	0.609	0.391
W01 Fall on same level from slipping, tripping and stumbling	0.609	0.391
W00 Fall on same level involving ice and snow	0.609	0.391
W13 Fall from, out of or through building or structure	0.609	0.391
Q50-Q56 Congenital malformations of genital organs	0.608	0.391
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.608	0.392
M94.89 Other specified disorders of cartilage (Site unspecified)	0.608	0.392
M94.87 Other specified disorders of cartilage (Ankle and foot)	0.608	0.392
M94.85 Other specified disorders of cartilage (Pelvic region and thigh)	0.608	0.392
M94.84 Other specified disorders of cartilage (Hand)	0.608	0.392
M94.83 Other specified disorders of cartilage (Forearm)	0.608	0.392
M94.82 Other specified disorders of cartilage (Upper arm)	0.608	0.392
M94.81 Other specified disorders of cartilage (Shoulder region)	0.608	0.392
M94.80 Other specified disorders of cartilage (Multiple sites)	0.608	0.392
S72.9 Fracture of femur, part unspecified	0.608	0.392
S72.8 Fractures of other parts of femur	0.608	0.392
S72.7 Multiple fractures of femur	0.608	0.392
S72.2 Subtrochanteric fracture	0.608	0.392
M25.4 Effusion of joint	0.608	0.392
T16 Foreign body in ear	0.607	0.393
Y40.1 Cefalosporins and other -lactam antibiotics	0.607	0.393
S59 Other and unspecified injuries of forearm	0.607	0.393
T18 Foreign body in alimentary tract	0.606	0.394
H44 Disorders of globe	0.606	0.394
H54 Blindness and low vision	0.605	0.395
T23 Burn and corrosion of wrist and hand	0.604	0.396
M81.9 Osteoporosis, unspecified	0.604	0.396
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.604	0.396

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations