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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75376680
log Bayes Factor = 19.3682
Chromosome 3   position 18,052,434  (GRCh37) Explore rs75376680 on Ensembl!
Variant rs75376680 is part of Cluster X0043

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
J40-J47 Chronic lower respiratory diseases
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.998 0.002 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.998 0.002 0.000
J44 Other chronic obstructive pulmonary disease
0.996 0.004 0.000
S00-S09 Injuries to the head
0.996 0.004 0.000
M05-M14 Inflammatory polyarthropathies
0.995 0.005 0.000
Chapter XX External causes of morbidity and mortality
0.990 0.010 0.000
Z50 Care involving use of rehabilitation procedures
0.988 0.012 0.000
M20-M25 Other joint disorders
0.983 0.017 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.982 0.018 0.000
H43-H45 Disorders of vitreous body and globe
0.978 0.022 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.977 0.023 0.000
Chapter VI Diseases of the nervous system
0.977 0.023 0.000
Z87 Personal history of other diseases and conditions
0.972 0.028 0.000
Z96 Presence of other functional implants
0.965 0.035 0.000
Z50.1 Other physical therapy
0.964 0.036 0.000
M06 Other rheumatoid arthritis
0.961 0.039 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.957 0.043 0.000
J47 Bronchiectasis
0.956 0.044 0.000
M45-M49 Spondylopathies
0.956 0.044 0.000
I20-I25 Ischaemic heart diseases
0.954 0.046 0.000
I71 Aortic aneurysm and dissection
0.953 0.047 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.952 0.048 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.949 0.051 0.000
Z88.6 Personal history of allergy to analgesic agent
0.937 0.063 0.000
Z96.0 Presence of urogenital implants
0.935 0.065 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.934 0.066 0.000
M06.9 Rheumatoid arthritis, unspecified
0.932 0.068 0.000
S00 Superficial injury of head
0.932 0.068 0.000
S01 Open wound of head
0.930 0.070 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.927 0.073 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.925 0.075 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.919 0.080 0.000
J43 Emphysema
0.918 0.082 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.917 0.083 0.000
H43 Disorders of vitreous body
0.917 0.083 0.000
M10 Gout
0.916 0.084 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.915 0.085 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.912 0.088 0.000
G90-G99 Other disorders of the nervous system
0.910 0.090 0.000
Z53.8 Procedure not carried out for other reasons
0.909 0.091 0.000
M47 Spondylosis
0.908 0.092 0.000
H44 Disorders of globe
0.908 0.092 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.907 0.093 0.000
J40 Bronchitis, not specified as acute or chronic
0.907 0.093 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.906 0.094 0.000
Z83 Family history of other specific disorders
0.904 0.096 0.000
M25 Other joint disorders, not elsewhere classified
0.904 0.096 0.000
Z94 Transplanted organ and tissue status
0.901 0.099 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.900 0.100 0.000
Chapter VIII Diseases of the ear and mastoid process
0.899 0.101 0.000
Z47 Other orthopaedic follow-up care
0.898 0.102 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.897 0.103 0.000
J45 Asthma
0.897 0.103 0.000
S02 Fracture of skull and facial bones
0.896 0.104 0.000
H30-H36 Disorders of choroid and retina
0.896 0.104 0.000
M11 Other crystal arthropathies
0.893 0.107 0.000
H40-H42 Glaucoma
0.892 0.108 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.892 0.108 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.890 0.110 0.000
Z96.6 Presence of orthopaedic joint implants
0.886 0.114 0.000
G30-G32 Other degenerative diseases of the nervous system
0.885 0.115 0.000
I95 Hypotension
0.882 0.118 0.000
Z46 Fitting and adjustment of other devices
0.879 0.121 0.000
Z95.1 Presence of aortocoronary bypass graft
0.879 0.121 0.000
H35 Other retinal disorders
0.875 0.125 0.000
W00-W19 Falls
0.874 0.126 0.000
S00.9 Superficial injury of head, part unspecified
0.872 0.128 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.871 0.129 0.000
M21 Other acquired deformities of limbs
0.866 0.134 0.000
M47.8 Other spondylosis
0.865 0.135 0.000
Z50.5 Speech therapy
0.864 0.136 0.000
M24 Other specific joint derangements
0.862 0.138 0.000
J43.9 Emphysema, unspecified
0.860 0.140 0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities
0.860 0.140 0.000
M10.9 Gout, unspecified
0.860 0.140 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.859 0.141 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.858 0.142 0.000
H44.2 Degenerative myopia
0.857 0.143 0.000
Chapter XXII Codes for special purposes
0.856 0.144 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.855 0.145 0.000
H55-H59 Other disorders of eye and adnexa
0.850 0.150 0.000
I72 Other aneurysm
0.849 0.151 0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue
0.849 0.151 0.000
I22 Subsequent myocardial infarction
0.846 0.154 0.000
M23 Internal derangement of knee
0.846 0.154 0.000
M47.82 Other spondylosis (Cervical region)
0.846 0.154 0.000
M86-M90 Other osteopathies
0.844 0.156 0.000
H53-H54 Visual disturbances and blindness
0.844 0.156 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.842 0.158 0.000
Z96.7 Presence of other bone and tendon implants
0.839 0.161 0.000
S01.3 Open wound of ear
0.838 0.162 0.000
M65-M68 Disorders of synovium and tendon
0.836 0.164 0.000
I24 Other acute ischaemic heart diseases
0.836 0.164 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.836 0.164 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.835 0.165 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.835 0.165 0.000
S70-S79 Injuries to the hip and thigh
0.833 0.167 0.000
Z94.8 Other transplanted organ and tissue status
0.832 0.168 0.000
S60-S69 Injuries to the wrist and hand
0.832 0.168 0.000
X60-X84 Intentional self-harm
0.831 0.169 0.000
I21 Acute myocardial infarction
0.831 0.169 0.000
M10.99 Gout, unspecified (Site unspecified)
0.830 0.170 0.000
Z83.3 Family history of diabetes mellitus
0.825 0.175 0.000
S01.0 Open wound of scalp
0.823 0.177 0.000
I95.9 Hypotension, unspecified
0.823 0.177 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.821 0.179 0.000
I30-I52 Other forms of heart disease
0.820 0.180 0.000
S90-S99 Injuries to the ankle and foot
0.820 0.180 0.000
M11.2 Other chondrocalcinosis
0.819 0.181 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.817 0.183 0.000
H40 Glaucoma
0.816 0.184 0.000
H65-H75 Diseases of middle ear and mastoid
0.814 0.185 0.000
S80-S89 Injuries to the knee and lower leg
0.814 0.186 0.000
J30-J39 Other diseases of upper respiratory tract
0.813 0.187 0.000
M45 Ankylosing spondylitis
0.813 0.187 0.000
M91-M94 Chondropathies
0.812 0.187 0.000
M25.7 Osteophyte
0.813 0.187 0.000
S09 Other and unspecified injuries of head
0.811 0.189 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.811 0.189 0.000
G95 Other diseases of spinal cord
0.811 0.189 0.000
H18 Other disorders of cornea
0.810 0.189 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.810 0.190 0.000
S00.8 Superficial injury of other parts of head
0.809 0.191 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.807 0.193 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.807 0.193 0.000
Z44 Fitting and adjustment of external prosthetic device
0.805 0.195 0.000
H43.8 Other disorders of vitreous body
0.805 0.195 0.000
G30 Alzheimer's disease
0.804 0.196 0.000
I74 Arterial embolism and thrombosis
0.802 0.198 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.802 0.198 0.000
I60-I69 Cerebrovascular diseases
0.801 0.199 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.798 0.202 0.000
W50-W64 Exposure to animate mechanical forces
0.798 0.202 0.000
G20-G26 Extrapyramidal and movement disorders
0.797 0.203 0.000
Z42 Follow-up care involving plastic surgery
0.796 0.204 0.000
S01.1 Open wound of eyelid and periocular area
0.794 0.206 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.794 0.206 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.792 0.208 0.000
S02.1 Fracture of base of skull
0.792 0.208 0.000
Z50.2 Alcohol rehabilitation
0.791 0.209 0.000
Z87.8 Personal history of other specified conditions
0.790 0.210 0.000
H35.8 Other specified retinal disorders
0.790 0.210 0.000
S06 Intracranial injury
0.789 0.211 0.000
Z95.3 Presence of xenogenic heart valve
0.788 0.211 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.788 0.212 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.784 0.216 0.000
H43.3 Other vitreous opacities
0.783 0.217 0.000
I78 Diseases of capillaries
0.782 0.218 0.000
M35 Other systemic involvement of connective tissue
0.780 0.220 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.779 0.221 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.778 0.222 0.000
M22 Disorders of patella
0.774 0.226 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.772 0.228 0.000
V10-V19 Pedal cyclist injured in transport accident
0.771 0.229 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.770 0.230 0.000
Z45 Adjustment and management of implanted device
0.769 0.231 0.000
J45.0 Predominantly allergic asthma
0.768 0.232 0.000
S40-S49 Injuries to the shoulder and upper arm
0.767 0.233 0.000
J00-J06 Acute upper respiratory infections
0.767 0.233 0.000
M11.26 Other chondrocalcinosis (Lower leg)
0.767 0.233 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.765 0.235 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.764 0.236 0.000
Z95.0 Presence of cardiac pacemaker
0.763 0.237 0.000
T79-T79 Certain early complications of trauma
0.763 0.237 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.763 0.237 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.762 0.238 0.000
I05-I09 Chronic rheumatic heart diseases
0.762 0.238 0.000
H65 Nonsuppurative otitis media
0.762 0.238 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.761 0.239 0.000
I61 Intracerebral haemorrhage
0.761 0.239 0.000
J95-J99 Other diseases of the respiratory system
0.759 0.241 0.000
H53 Visual disturbances
0.757 0.243 0.000
I25 Chronic ischaemic heart disease
0.756 0.244 0.000
H35.7 Separation of retinal layers
0.756 0.244 0.000
G70-G73 Diseases of myoneural junction and muscle
0.755 0.245 0.000
G90 Disorders of autonomic nervous system
0.755 0.245 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.755 0.245 0.000
T86 Failure and rejection of transplanted organs and tissues
0.754 0.246 0.000
H25-H28 Disorders of lens
0.753 0.247 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.752 0.248 0.000
J45.9 Asthma, unspecified
0.752 0.248 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.751 0.249 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.750 0.250 0.000
S50-S59 Injuries to the elbow and forearm
0.749 0.251 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.749 0.251 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.749 0.251 0.000
M60-M63 Disorders of muscles
0.748 0.252 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.747 0.253 0.000
Z92 Personal history of medical treatment
0.747 0.253 0.000
M05 Seropositive rheumatoid arthritis
0.746 0.253 0.000
G30.9 Alzheimer's disease, unspecified
0.746 0.254 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.746 0.254 0.000
D50-D53 Nutritional anaemias
0.746 0.254 0.000
Z89 Acquired absence of limb
0.745 0.255 0.000
H60-H62 Diseases of external ear
0.745 0.255 0.000
H18.8 Other specified disorders of cornea
0.744 0.256 0.000
H21 Other disorders of iris and ciliary body
0.743 0.257 0.000
Z46.6 Fitting and adjustment of urinary device
0.743 0.257 0.000
V40-V49 Car occupant injured in transport accident
0.741 0.258 0.000
I21.4 Acute subendocardial myocardial infarction
0.741 0.259 0.000
Z49 Care involving dialysis
0.739 0.261 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.738 0.262 0.000
J33 Nasal polyp
0.737 0.263 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.736 0.264 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.735 0.265 0.000
M06.0 Seronegative rheumatoid arthritis
0.735 0.265 0.000
M47.9 Spondylosis, unspecified
0.735 0.265 0.000
S10-S19 Injuries to the neck
0.734 0.266 0.000
X20-X29 Contact with venomous animals and plants
0.733 0.266 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.733 0.267 0.000
M15-M19 Arthrosis
0.732 0.268 0.000
M40-M43 Deforming dorsopathies
0.731 0.269 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.730 0.270 0.000
I10-I15 Hypertensive diseases
0.728 0.272 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.728 0.272 0.000
Z81 Family history of mental and behavioural disorders
0.727 0.273 0.000
M31 Other necrotising vasculopathies
0.727 0.273 0.000
M80-M85 Disorders of bone density and structure
0.726 0.274 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.726 0.274 0.000
T66-T78 Other and unspecified effects of external causes
0.726 0.274 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.724 0.276 0.000
Z46.8 Fitting and adjustment of other specified devices
0.724 0.276 0.000
S02.5 Fracture of tooth
0.723 0.277 0.000
M13 Other arthritis
0.722 0.278 0.000
I35 Nonrheumatic aortic valve disorders
0.721 0.279 0.000
H43.1 Vitreous haemorrhage
0.721 0.279 0.000
M25.8 Other specified joint disorders
0.720 0.280 0.000
M65 Synovitis and tenosynovitis
0.720 0.280 0.000
T93 Sequelae of injuries of lower limb
0.719 0.281 0.000
Z97 Presence of other devices
0.719 0.281 0.000
W07 Fall involving chair
0.719 0.281 0.000
S02.10 Fracture of base of skull (closed)
0.717 0.283 0.000
S64 Injury of nerves at wrist and hand level
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
J41 Simple and mucopurulent chronic bronchitis
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
H40.0 Glaucoma suspect
0.716 0.284 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.716 0.284 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.716 0.284 0.000
Z54 Convalescence
0.716 0.284 0.000
G91 Hydrocephalus
0.716 0.284 0.000
H66 Suppurative and unspecified otitis media
0.716 0.284 0.000
H57 Other disorders of eye and adnexa
0.715 0.285 0.000
I31 Other diseases of pericardium
0.714 0.285 0.000
S08 Traumatic amputation of part of head
0.714 0.286 0.000
S07 Crushing injury of head
0.714 0.286 0.000
S05 Injury of eye and orbit
0.714 0.286 0.000
S04 Injury of cranial nerves
0.714 0.286 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.714 0.286 0.000
M14 Arthropathies in other diseases classified elsewhere
0.714 0.286 0.000
M12 Other specific arthropathies
0.714 0.286 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.714 0.286 0.000
M08 Juvenile arthritis
0.714 0.286 0.000
I70 Atherosclerosis
0.713 0.287 0.000
H35.0 Background retinopathy and retinal vascular changes
0.711 0.289 0.000
Y35-Y36 Legal intervention and operations of war
0.710 0.290 0.000
Y10-Y34 Event of undetermined intent
0.710 0.290 0.000
Y00-Y09 Assault
0.710 0.290 0.000
X85-X99 Assault
0.710 0.290 0.000
X50-X57 Overexertion, travel and privation
0.710 0.290 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.710 0.290 0.000
X30-X39 Exposure to forces of nature
0.710 0.290 0.000
X10-X19 Contact with heat and hot substances
0.710 0.290 0.000
X00-X09 Exposure to smoke, fire and flames
0.710 0.290 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.710 0.290 0.000
W75-W84 Other accidental threats to breathing
0.710 0.290 0.000
W65-W74 Accidental drowning and submersion
0.710 0.290 0.000
W20-W49 Exposure to inanimate mechanical forces
0.710 0.290 0.000
V98-V99 Other and unspecified transport accidents
0.710 0.290 0.000
V95-V97 Air and space transport accidents
0.710 0.290 0.000
V90-V94 Water transport accidents
0.710 0.290 0.000
V70-V79 Bus occupant injured in transport accident
0.710 0.290 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.710 0.290 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.710 0.290 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.710 0.290 0.000
V01-V09 Pedestrian injured in transport accident
0.710 0.290 0.000
Z88.2 Personal history of allergy to sulphonamides
0.709 0.291 0.000
M21.2 Flexion deformity
0.709 0.291 0.000
G95.2 Cord compression, unspecified
0.709 0.291 0.000
Z50.6 Orthoptic training
0.708 0.292 0.000
Z50.3 Drug rehabilitation
0.708 0.292 0.000
H65.3 Chronic mucoid otitis media
0.708 0.292 0.000
Z93 Artificial opening status
0.708 0.292 0.000
V20-V29 Motorcycle rider injured in transport accident
0.707 0.293 0.000
M00-M03 Infectious arthropathies
0.707 0.293 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.706 0.294 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.706 0.294 0.000
Z83.4 Family history of other endocrine, nutritional and metabolic diseases
0.705 0.295 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.704 0.295 0.000
M33 Dermatopolymyositis
0.704 0.295 0.000
M32 Systemic lupus erythematosus
0.704 0.295 0.000
M30 Polyarteritis nodosa and related conditions
0.704 0.295 0.000
H35.2 Other proliferative retinopathy
0.703 0.297 0.000
H53.2 Diplopia
0.703 0.297 0.000
I99 Other and unspecified disorders of circulatory system
0.702 0.298 0.000
D60-D64 Aplastic and other anaemias
0.702 0.298 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.701 0.299 0.000
Y52 Agents primarily affecting the cardiovascular system
0.701 0.299 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.701 0.299 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.700 0.300 0.000
S79 Other and unspecified injuries of hip and thigh
0.700 0.300 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.698 0.302 0.000
W08 Fall involving other furniture
0.697 0.303 0.000
Z87.6 Personal history of certain conditions arising in the perinatal period
0.697 0.303 0.000
I95.2 Hypotension due to drugs
0.697 0.303 0.000
Z43 Attention to artificial openings
0.697 0.303 0.000
S20-S29 Injuries to the thorax
0.697 0.303 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.697 0.303 0.000
Z88.5 Personal history of allergy to narcotic agent
0.697 0.303 0.000
I72.4 Aneurysm of artery of lower extremity
0.696 0.304 0.000
H35.3 Degeneration of macula and posterior pole
0.695 0.305 0.000
H16 Keratitis
0.694 0.306 0.000
S02.3 Fracture of orbital floor
0.693 0.306 0.000
Z95.4 Presence of other heart-valve replacement
0.693 0.307 0.000
M89 Other disorders of bone
0.692 0.308 0.000
Z96.9 Presence of functional implant, unspecified
0.692 0.308 0.000
Z96.5 Presence of tooth-root and mandibular implants
0.692 0.308 0.000
Z96.4 Presence of endocrine implants
0.692 0.308 0.000
Z96.3 Presence of artificial larynx
0.692 0.308 0.000
Z96.2 Presence of otological and audiological implants
0.692 0.308 0.000
S02.0 Fracture of vault of skull
0.692 0.308 0.000
S32 Fracture of lumbar spine and pelvis
0.692 0.308 0.000
Z83.5 Family history of eye and ear disorders
0.692 0.308 0.000
M23.8 Other internal derangements of knee
0.691 0.308 0.000
Z47.8 Other specified orthopaedic follow-up care
0.691 0.309 0.000
Z42.9 Follow-up care involving plastic surgery, unspecified
0.691 0.309 0.000
Y45.0 Opioids and related analgesics
0.691 0.309 0.000
J34 Other disorders of nose and nasal sinuses
0.690 0.310 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.690 0.310 0.000
G62 Other polyneuropathies
0.690 0.310 0.000
M06.8 Other specified rheumatoid arthritis
0.689 0.311 0.000
M06.4 Inflammatory polyarthropathy
0.689 0.311 0.000
M06.3 Rheumatoid nodule
0.689 0.311 0.000
M06.2 Rheumatoid bursitis
0.689 0.311 0.000
M06.1 Adult-onset Still's disease
0.689 0.311 0.000
J42 Unspecified chronic bronchitis
0.689 0.311 0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure
0.689 0.311 0.000
H26 Other cataract
0.688 0.312 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.688 0.312 0.000
W19 Unspecified fall
0.688 0.312 0.000
V80-V89 Other land transport accidents
0.687 0.312 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.687 0.313 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.686 0.314 0.000
H20 Iridocyclitis
0.686 0.314 0.000
D52 Folate deficiency anaemia
0.685 0.314 0.000
M49 Spondylopathies in diseases classified elsewhere
0.685 0.315 0.000
W10 Fall on and from stairs and steps
0.685 0.315 0.000
M25.78 Osteophyte (Other)
0.684 0.315 0.000
I23 Certain current complications following acute myocardial infarction
0.684 0.316 0.000
H80-H83 Diseases of inner ear
0.684 0.316 0.000
Z80 Family history of malignant neoplasm
0.684 0.316 0.000
M24.1 Other articular cartilage disorders
0.683 0.317 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.683 0.317 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.683 0.317 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.683 0.317 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.683 0.317 0.000
I71.0 Dissection of aorta [any part]
0.683 0.317 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.683 0.317 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.683 0.317 0.000
S80 Superficial injury of lower leg
0.681 0.318 0.000
M25.77 Osteophyte (Ankle and foot)
0.681 0.319 0.000
I35.8 Other aortic valve disorders
0.681 0.319 0.000
M21.4 Flat foot [pes planus] (acquired)
0.681 0.319 0.000
M07 Psoriatic and enteropathic arthropathies
0.680 0.320 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.680 0.320 0.000
J46 Status asthmaticus
0.679 0.321 0.000
H55 Nystagmus and other irregular eye movements
0.678 0.322 0.000
I74.5 Embolism and thrombosis of iliac artery
0.677 0.322 0.000
M25.3 Other instability of joint
0.677 0.323 0.000
I49 Other cardiac arrhythmias
0.677 0.323 0.000
Y95 Nosocomial condition
0.676 0.324 0.000
T90 Sequelae of injuries of head
0.675 0.325 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.675 0.325 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.675 0.325 0.000
M86 Osteomyelitis
0.675 0.325 0.000
J60-J70 Lung diseases due to external agents
0.674 0.326 0.000
Y57 Other and unspecified drugs and medicaments
0.673 0.327 0.000
M21.6 Other acquired deformities of ankle and foot
0.673 0.327 0.000
S92 Fracture of foot, except ankle
0.673 0.327 0.000
Chapter I Certain infectious and parasitic diseases
0.673 0.327 0.000
H46 Optic neuritis
0.672 0.328 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.672 0.328 0.000
H34 Retinal vascular occlusions
0.672 0.328 0.000
J33.8 Other polyp of sinus
0.672 0.328 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.671 0.329 0.000
M24.2 Disorder of ligament
0.670 0.329 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.670 0.330 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.670 0.330 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.670 0.330 0.000
G61 Inflammatory polyneuropathy
0.669 0.331 0.000
Z45.8 Adjustment and management of other implanted devices
0.669 0.331 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.668 0.331 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.668 0.331 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.668 0.331 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.668 0.331 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.668 0.332 0.000
J09-J18 Influenza and pneumonia
0.668 0.332 0.000
H35.9 Retinal disorder, unspecified
0.668 0.332 0.000
S00.7 Multiple superficial injuries of head
0.668 0.332 0.000
S00.5 Superficial injury of lip and oral cavity
0.668 0.332 0.000
S00.4 Superficial injury of ear
0.668 0.332 0.000
S00.3 Superficial injury of nose
0.668 0.332 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.668 0.332 0.000
I72.8 Aneurysm of other specified arteries
0.668 0.332 0.000
J02 Acute pharyngitis
0.668 0.332 0.000
S01.2 Open wound of nose
0.668 0.332 0.000
M24.0 Loose body in joint
0.668 0.332 0.000
M34 Systemic sclerosis
0.667 0.332 0.000
Y44 Agents primarily affecting blood constituents
0.667 0.333 0.000
Z44.3 Fitting and adjustment of external breast prosthesis
0.667 0.333 0.000
M25.0 Haemarthrosis
0.667 0.333 0.000
S01.7 Multiple open wounds of head
0.666 0.333 0.000
S01.4 Open wound of cheek and temporomandibular area
0.666 0.333 0.000
Y59 Other and unspecified vaccines and biological substances
0.665 0.335 0.000
Y58 Bacterial vaccines
0.665 0.335 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.665 0.335 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.665 0.335 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.665 0.335 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.665 0.335 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.665 0.335 0.000
Y48 Anaesthetics and therapeutic gases
0.665 0.335 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.665 0.335 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.665 0.335 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.665 0.335 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.664 0.336 0.000
I95.1 Orthostatic hypotension
0.664 0.336 0.000
S81 Open wound of lower leg
0.664 0.336 0.000
H52 Disorders of refraction and accommodation
0.663 0.337 0.000
X78 Intentional self-harm by sharp object
0.662 0.338 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.660 0.340 0.000
W55 Bitten or struck by other mammals
0.660 0.340 0.000
H40.2 Primary angle-closure glaucoma
0.660 0.340 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.659 0.341 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.659 0.341 0.000
H17 Corneal scars and opacities
0.659 0.341 0.000
H15 Disorders of sclera
0.659 0.341 0.000
J43.8 Other emphysema
0.658 0.341 0.000
J43.2 Centrilobular emphysema
0.658 0.341 0.000
J43.1 Panlobular emphysema
0.658 0.341 0.000
J43.0 MacLeod's syndrome
0.658 0.341 0.000
M35.0 Sicca syndrome [Sjogren]
0.658 0.342 0.000
I72.3 Aneurysm of iliac artery
0.658 0.342 0.000
G20 Parkinson's disease
0.658 0.342 0.000
H43.9 Disorder of vitreous body, unspecified
0.657 0.343 0.000
H43.2 Crystalline deposits in vitreous body
0.657 0.343 0.000
H43.0 Vitreous prolapse
0.657 0.343 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.657 0.343 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.657 0.343 0.000
M10.4 Other secondary gout
0.657 0.343 0.000
M10.3 Gout due to impairment of renal function
0.657 0.343 0.000
M10.2 Drug-induced gout
0.657 0.343 0.000
M10.1 Lead-induced gout
0.657 0.343 0.000
M10.0 Idiopathic gout
0.657 0.343 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.657 0.343 0.000
Y40 Systemic antibiotics
0.656 0.344 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.655 0.345 0.000
Z63 Other problems related to primary support group, including family circumstances
0.655 0.345 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.655 0.345 0.000
G40-G47 Episodic and paroxysmal disorders
0.654 0.345 0.000
J84 Other interstitial pulmonary diseases
0.654 0.346 0.000
M70-M79 Other soft tissue disorders
0.654 0.346 0.000
M23.3 Other meniscus derangements
0.653 0.347 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.653 0.347 0.000
M46 Other inflammatory spondylopathies
0.652 0.347 0.000
H10-H13 Disorders of conjunctiva
0.652 0.347 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.652 0.348 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.652 0.348 0.000
G92 Toxic encephalopathy
0.652 0.348 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.652 0.348 0.000
M48 Other spondylopathies
0.651 0.349 0.000
M47.1 Other spondylosis with myelopathy
0.651 0.349 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.651 0.349 0.000
M25.76 Osteophyte (Lower leg)
0.651 0.349 0.000
H44.9 Disorder of globe, unspecified
0.651 0.349 0.000
H44.8 Other disorders of globe
0.651 0.349 0.000
H44.7 Retained (old) intraocular foreign body, nonmagnetic
0.651 0.349 0.000
H44.6 Retained (old) intraocular foreign body, magnetic
0.651 0.349 0.000
H44.5 Degenerated conditions of globe
0.651 0.349 0.000
H44.4 Hypotony of eye
0.651 0.349 0.000
H44.3 Other degenerative disorders of globe
0.651 0.349 0.000
H44.1 Other endophthalmitis
0.651 0.349 0.000
H44.0 Purulent endophthalmitis
0.651 0.349 0.000
M24.5 Contracture of joint
0.650 0.349 0.000
T86.8 Failure and rejection of other transplanted organs and tissues
0.650 0.350 0.000
S09.8 Other specified injuries of head
0.650 0.350 0.000
H61 Other disorders of external ear
0.649 0.351 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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