TreeWAS – Variant ID: rs75461507

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000
Chapter II Neoplasms	1.000	0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal	1.000	0.000
D10-D36 Benign neoplasms	0.999	0.001
Chapter XI Diseases of the digestive system	0.997	0.003
I30-I52 Other forms of heart disease	0.996	0.004
Chapter XII Diseases of the skin and subcutaneous tissue	0.996	0.004
I60-I69 Cerebrovascular diseases	0.995	0.005
D12.3 Transverse colon	0.993	0.007
Chapter XIV Diseases of the genitourinary system	0.992	0.008
N17-N19 Renal failure	0.992	0.008
N18 Chronic renal failure	0.989	0.011
K70-K77 Diseases of liver	0.988	0.012
L80-L99 Other disorders of the skin and subcutaneous tissue	0.987	0.013
Chapter VII Diseases of the eye and adnexa	0.983	0.017
N18.9 Chronic renal failure, unspecified	0.980	0.020
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.976	0.024
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.974	0.026
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.973	0.027
L97 Ulcer of lower limb, not elsewhere classified	0.971	0.029
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.965	0.035
K70 Alcoholic liver disease	0.964	0.036
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.960	0.040
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.957	0.043
K55-K64 Other diseases of intestines	0.955	0.045
Chapter IV Endocrine, nutritional and metabolic diseases	0.954	0.046
I67 Other cerebrovascular diseases	0.954	0.046
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.953	0.047
D12.5 Sigmoid colon	0.945	0.055
I50 Heart failure	0.943	0.057
I84 Haemorrhoids	0.942	0.058
I45 Other conduction disorders	0.941	0.059
C34 Malignant neoplasm of bronchus and lung	0.940	0.060
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.939	0.061
I10-I15 Hypertensive diseases	0.936	0.064
I51 Complications and ill-defined descriptions of heart disease	0.931	0.069
K90-K93 Other diseases of the digestive system	0.928	0.072
M50-M54 Other dorsopathies	0.927	0.073
E70-E90 Metabolic disorders	0.925	0.075
D68 Other coagulation defects	0.923	0.077
E87 Other disorders of fluid, electrolyte and acid-base balance	0.922	0.078
I84.8 Unspecified haemorrhoids with other complications	0.921	0.079
D12.0 Caecum	0.919	0.081
K62 Other diseases of anus and rectum	0.913	0.087
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.910	0.090
I12 Hypertensive renal disease	0.908	0.092
L20-L30 Dermatitis and eczema	0.907	0.093
D12.6 Colon, unspecified	0.907	0.093
H30-H36 Disorders of choroid and retina	0.906	0.094
K76 Other diseases of liver	0.905	0.095
I51.7 Cardiomegaly	0.904	0.096
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.901	0.099
N40-N51 Diseases of male genital organs	0.899	0.101
Chapter XV Pregnancy, childbirth and the puerperium	0.898	0.102
D12.4 Descending colon	0.897	0.103
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.896	0.104
K60 Fissure and fistula of anal and rectal regions	0.896	0.104
E87.5 Hyperkalaemia	0.895	0.105
L82 Seborrhoeic keratosis	0.894	0.106
E87.1 Hypo-osmolality and hyponatraemia	0.891	0.109
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.890	0.110
C34.9 Bronchus or lung, unspecified	0.889	0.111
I45.1 Other and unspecified right bundle-branch block	0.887	0.113
M50 Cervical disk disorders	0.887	0.113
I67.9 Cerebrovascular disease, unspecified	0.886	0.114
R93 Abnormal findings on diagnostic imaging of other body structures	0.885	0.115
I69 Sequelae of cerebrovascular disease	0.885	0.115
K62.8 Other specified diseases of anus and rectum	0.882	0.118
D68.9 Coagulation defect, unspecified	0.882	0.118
L00-L08 Infections of the skin and subcutaneous tissue	0.880	0.120
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.880	0.120
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.879	0.121
S00-S09 Injuries to the head	0.878	0.122
I12.0 Hypertensive renal disease with renal failure	0.877	0.123
N19 Unspecified renal failure	0.876	0.124
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.875	0.125
I44 Atrioventricular and left bundle-branch block	0.875	0.125
K92 Other diseases of digestive system	0.875	0.125
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.874	0.126
I60 Subarachnoid haemorrhage	0.872	0.128
K08 Other disorders of teeth and supporting structures	0.867	0.133
L98.9 Disorder of skin and subcutaneous tissue, unspecified	0.860	0.140
I42 Cardiomyopathy	0.860	0.140
D35 Benign neoplasm of other and unspecified endocrine glands	0.860	0.140
I50.1 Left ventricular failure	0.860	0.140
H55-H59 Other disorders of eye and adnexa	0.860	0.140
K70.9 Alcoholic liver disease, unspecified	0.858	0.142
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.858	0.142
H35 Other retinal disorders	0.858	0.142
N17 Acute renal failure	0.857	0.143
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.857	0.143
K70.1 Alcoholic hepatitis	0.856	0.144
K58 Irritable bowel syndrome	0.853	0.147
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.850	0.149
N00-N08 Glomerular diseases	0.848	0.152
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.845	0.155
D23 Other benign neoplasms of skin	0.845	0.155
E20-E35 Disorders of other endocrine glands	0.844	0.156
R15 Faecal incontinence	0.843	0.157
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.841	0.159
N18.0 End-stage renal disease	0.838	0.162
Chapter VI Diseases of the nervous system	0.838	0.162
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.837	0.163
H04 Disorders of lachrymal system	0.833	0.167
D34 Benign neoplasm of thyroid gland	0.830	0.170
K70.3 Alcoholic cirrhosis of liver	0.830	0.170
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.829	0.171
N18.3 Chronic kidney disease, stage 3	0.826	0.174
K92.1 Melaena	0.824	0.176
I61 Intracerebral haemorrhage	0.823	0.177
K76.6 Portal hypertension	0.822	0.178
M45-M49 Spondylopathies	0.822	0.178
I62 Other nontraumatic intracranial haemorrhage	0.818	0.182
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.818	0.182
M50.3 Other cervical disk degeneration	0.814	0.186
K60.1 Chronic anal fissure	0.814	0.186
D37-D48 Neoplasms of uncertain or unknown behaviour	0.814	0.186
D12.2 Ascending colon	0.812	0.188
R80 Isolated proteinuria	0.808	0.192
K04 Diseases of pulp and periapical tissues	0.807	0.192
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.807	0.193
M40-M43 Deforming dorsopathies	0.805	0.195
L29 Pruritus	0.803	0.197
K55 Vascular disorders of intestine	0.803	0.197
K62.1 Rectal polyp	0.799	0.201
S80-S89 Injuries to the knee and lower leg	0.799	0.201
I70-I79 Diseases of arteries, arterioles and capillaries	0.798	0.202
C34.3 Lower lobe, bronchus or lung	0.798	0.202
D68.2 Hereditary deficiency of other clotting factors	0.796	0.204
D18 Haemangioma and lymphangioma, any site	0.796	0.204
I84.9 Unspecified haemorrhoids without complication	0.796	0.204
L85 Other epidermal thickening	0.795	0.205
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.794	0.206
K72 Hepatic failure, not elsewhere classified	0.794	0.206
N48 Other disorders of penis	0.793	0.207
M50.1 Cervical disk disorder with radiculopathy	0.792	0.208
Chapter XX External causes of morbidity and mortality	0.791	0.209
O36 Maternal care for other known or suspected foetal problems	0.790	0.210
K00 Disorders of tooth development and eruption	0.790	0.210
K58.9 Irritable bowel syndrome without diarrhoea	0.788	0.212
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.787	0.213
I65.2 Occlusion and stenosis of carotid artery	0.787	0.213
M91-M94 Chondropathies	0.786	0.214
I84.5 External haemorrhoids without complication	0.785	0.215
G90-G99 Other disorders of the nervous system	0.785	0.215
D36 Benign neoplasm of other and unspecified sites	0.784	0.216
H04.5 Stenosis and insufficiency of lachrymal passages	0.783	0.217
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.783	0.217
I67.1 Cerebral aneurysm, nonruptured	0.782	0.218
S00 Superficial injury of head	0.781	0.219
I80 Phlebitis and thrombophlebitis	0.780	0.220
D68.5 Primary Thrombophilia	0.778	0.222
R17 Unspecified jaundice	0.778	0.222
I67.0 Dissection of cerebral arteries, nonruptured	0.777	0.223
K75 Other inflammatory liver diseases	0.777	0.223
D32 Benign neoplasm of meninges	0.775	0.225
M15-M19 Arthrosis	0.774	0.226
I67.2 Cerebral atherosclerosis	0.773	0.227
S20-S29 Injuries to the thorax	0.772	0.228
N18.4 Chronic kidney disease, stage 4	0.772	0.228
I84.1 Internal haemorrhoids with other complications	0.769	0.231
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.768	0.232
M86-M90 Other osteopathies	0.764	0.235
I60.9 Subarachnoid haemorrhage, unspecified	0.764	0.236
T15-T19 Effects of foreign body entering through natural orifice	0.763	0.237
I50.0 Congestive heart failure	0.762	0.238
M54 Dorsalgia	0.761	0.239
N17.9 Acute renal failure, unspecified	0.761	0.239
T98 Sequelae of other and unspecified effects of external causes	0.760	0.240
I50.9 Heart failure, unspecified	0.760	0.240
O36.8 Maternal care for other specified foetal problems	0.760	0.240
T66-T78 Other and unspecified effects of external causes	0.759	0.241
C60-C63 Malignant neoplasms of male genital organs	0.759	0.241
D13.2 Duodenum	0.757	0.243
S10-S19 Injuries to the neck	0.757	0.243
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.757	0.243
K08.9 Disorder of teeth and supporting structures, unspecified	0.757	0.243
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.755	0.245
S02 Fracture of skull and facial bones	0.754	0.246
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.752	0.248
R13 Dysphagia	0.751	0.249
N45 Orchitis and epididymitis	0.750	0.250
K60.3 Anal fistula	0.750	0.250
I12.9 Hypertensive renal disease without renal failure	0.748	0.252
Chapter XXII Codes for special purposes	0.745	0.255
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.743	0.257
L60-L75 Disorders of skin appendages	0.743	0.257
L30 Other dermatitis	0.742	0.258
K08.3 Retained dental root	0.742	0.258
H35.9 Retinal disorder, unspecified	0.741	0.259
I44.7 Left bundle-branch block, unspecified	0.741	0.259
T86 Failure and rejection of transplanted organs and tissues	0.739	0.261
R87 Abnormal findings in specimens from female genital organs	0.739	0.261
I45.5 Other specified heart block	0.738	0.261
C34.2 Middle lobe, bronchus or lung	0.738	0.262
I77 Other disorders of arteries and arterioles	0.737	0.263
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.737	0.263
O85-O92 Complications predominantly related to the puerperium	0.737	0.263
C64-C68 Malignant neoplasms of urinary tract	0.735	0.264
D12.7 Rectosigmoid junction	0.735	0.265
H02 Other disorders of eyelid	0.735	0.265
N25-N29 Other disorders of kidney and ureter	0.734	0.266
N99-N99 Other disorders of the genitourinary system	0.734	0.266
T93 Sequelae of injuries of lower limb	0.734	0.266
O20-O29 Other maternal disorders predominantly related to pregnancy	0.733	0.267
I42.0 Dilated cardiomyopathy	0.731	0.269
D10 Benign neoplasm of mouth and pharynx	0.729	0.271
K35-K38 Diseases of appendix	0.729	0.271
H35.3 Degeneration of macula and posterior pole	0.729	0.271
H10-H13 Disorders of conjunctiva	0.728	0.272
K70.4 Alcoholic hepatic failure	0.728	0.272
N03 Chronic nephritic syndrome	0.728	0.272
K76.8 Other specified diseases of liver	0.728	0.272
L28 Lichen simplex chronicus and prurigo	0.727	0.273
S05 Injury of eye and orbit	0.727	0.273
L05 Pilonidal cyst	0.726	0.274
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified	0.726	0.274
D35.2 Pituitary gland	0.726	0.274
H53-H54 Visual disturbances and blindness	0.726	0.274
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.726	0.274
E87.6 Hypokalaemia	0.725	0.275
S50-S59 Injuries to the elbow and forearm	0.724	0.276
K13 Other diseases of lip and oral mucosa	0.724	0.276
I31 Other diseases of pericardium	0.724	0.276
I84.0 Internal thrombosed haemorrhoids	0.724	0.276
K04.8 Radicular cyst	0.723	0.276
I44.2 Atrioventricular block, complete	0.723	0.277
I81 Portal vein thrombosis	0.723	0.277
H55 Nystagmus and other irregular eye movements	0.723	0.277
L02 Cutaneous abscess, furuncle and carbuncle	0.722	0.278
R47-R49 Symptoms and signs involving speech and voice	0.721	0.279
I38 Endocarditis, valve unspecified	0.721	0.279
D14 Benign neoplasm of middle ear and respiratory system	0.721	0.279
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.720	0.280
D11 Benign neoplasm of major salivary glands	0.720	0.280
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.720	0.280
I15 Secondary hypertension	0.717	0.283
D21 Other benign neoplasms of connective and other soft tissue	0.717	0.283
K12 Stomatitis and related lesions	0.717	0.283
K60.0 Acute anal fissure	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.717	0.283
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283
D12.9 Anus and anal canal	0.717	0.283
D12.1 Appendix	0.717	0.283
D31 Benign neoplasm of eye and adnexa	0.717	0.283
D30 Benign neoplasm of urinary organs	0.717	0.283
D29 Benign neoplasm of male genital organs	0.717	0.283
D28 Benign neoplasm of other and unspecified female genital organs	0.717	0.283
D26 Other benign neoplasms of uterus	0.717	0.283
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.717	0.283
D19 Benign neoplasm of mesothelial tissue	0.717	0.283
D16 Benign neoplasm of bone and articular cartilage	0.717	0.283
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.717	0.283
I44.1 Atrioventricular block, second degree	0.716	0.284
I52 Other heart disorders in diseases classified elsewhere	0.714	0.286
I48 Atrial fibrillation and flutter	0.714	0.286
I43 Cardiomyopathy in diseases classified elsewhere	0.714	0.286
I41 Myocarditis in diseases classified elsewhere	0.714	0.286
I40 Acute myocarditis	0.714	0.286
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.714	0.286
I37 Pulmonary valve disorders	0.714	0.286
I36 Nonrheumatic tricuspid valve disorders	0.714	0.286
I33 Acute and subacute endocarditis	0.714	0.286
I32 Pericarditis in diseases classified elsewhere	0.714	0.286
L10-L14 Bullous disorders	0.714	0.286
D50-D53 Nutritional anaemias	0.714	0.286
I68 Cerebrovascular disorders in diseases classified elsewhere	0.713	0.286
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.713	0.286
L89 Decubitus ulcer	0.712	0.288
K01 Embedded and impacted teeth	0.712	0.288
H57 Other disorders of eye and adnexa	0.712	0.288
T79-T79 Certain early complications of trauma	0.711	0.289
D23.3 Skin of other and unspecified parts of face	0.711	0.289
M65-M68 Disorders of synovium and tendon	0.711	0.289
C34.1 Upper lobe, bronchus or lung	0.710	0.290
S40-S49 Injuries to the shoulder and upper arm	0.709	0.291
K11 Diseases of salivary glands	0.709	0.291
C10 Malignant neoplasm of oropharynx	0.709	0.291
N18.8 Other chronic renal failure	0.709	0.291
N18.1 Chronic kidney disease, stage 1	0.709	0.291
K77 Liver disorders in diseases classified elsewhere	0.709	0.291
K73 Chronic hepatitis, not elsewhere classified	0.709	0.291
K71 Toxic liver disease	0.709	0.291
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.708	0.292
L95 Vasculitis limited to skin, not elsewhere classified	0.708	0.292
L94 Other localised connective tissue disorders	0.708	0.292
L93 Lupus erythematosus	0.708	0.292
L87 Transepidermal elimination disorders	0.708	0.292
L88 Pyoderma gangrenosum	0.708	0.292
L86 Keratoderma in diseases classified elsewhere	0.708	0.292
L83 Acanthosis nigricans	0.708	0.292
L80 Vitiligo	0.708	0.292
N18.5 Chronic kidney disease, stage 5	0.707	0.292
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.707	0.293
E50-E64 Other nutritional deficiencies	0.707	0.293
D23.4 Skin of scalp and neck	0.706	0.294
I30 Acute pericarditis	0.705	0.294
K62.6 Ulcer of anus and rectum	0.705	0.295
H46-H48 Disorders of optic nerve and visual pathways	0.705	0.295
N43 Hydrocele and spermatocele	0.705	0.295
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.705	0.295
K61 Abscess of anal and rectal regions	0.704	0.296
K06 Other disorders of gingiva and edentulous alveolar ridge	0.704	0.296
D13.1 Stomach	0.702	0.298
K09 Cysts of oral region, not elsewhere classified	0.702	0.298
I86 Varicose veins of other sites	0.702	0.298
L08 Other local infections of skin and subcutaneous tissue	0.702	0.298
M80-M85 Disorders of bone density and structure	0.701	0.299
M60-M63 Disorders of muscles	0.700	0.300
M00-M03 Infectious arthropathies	0.700	0.300
E87.2 Acidosis	0.700	0.300
K92.2 Gastro-intestinal haemorrhage, unspecified	0.700	0.300
O80-O84 Delivery	0.699	0.301
I61.9 Intracerebral haemorrhage, unspecified	0.699	0.301
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.699	0.301
L98.4 Chronic ulcer of skin, not elsewhere classified	0.699	0.301
R11 Nausea and vomiting	0.699	0.301
N10-N16 Renal tubulo-interstitial diseases	0.698	0.302
T33-T35 Frostbite	0.698	0.302
T26-T28 Burns and corrosions confined to eye and internal organs	0.698	0.302
T20-T25 Burns and corrosions of external body surface, specified by site	0.698	0.302
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.698	0.302
T00-T07 Injuries involving multiple body regions	0.698	0.302
C43-C44 Melanoma and other malignant neoplasms of skin	0.698	0.302
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.698	0.302
R95-R99 Ill-defined and unknown causes of mortality	0.697	0.303
D80-D89 Certain disorders involving the immune mechanism	0.697	0.303
E26 Hyperaldosteronism	0.696	0.304
N41 Inflammatory diseases of prostate	0.696	0.304
E87.3 Alkalosis	0.693	0.307
I46 Cardiac arrest	0.692	0.308
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.692	0.308
C38 Malignant neoplasm of heart, mediastinum and pleura	0.692	0.308
C32 Malignant neoplasm of larynx	0.692	0.308
C31 Malignant neoplasm of accessory sinuses	0.692	0.308
C30 Malignant neoplasm of nasal cavity and middle ear	0.692	0.308
C37 Malignant neoplasm of thymus	0.692	0.308
C33 Malignant neoplasm of trachea	0.692	0.308
I49 Other cardiac arrhythmias	0.691	0.309
K70.2 Alcoholic fibrosis and sclerosis of liver	0.691	0.309
K70.0 Alcoholic fatty liver	0.691	0.309
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.690	0.310
D69 Purpura and other haemorrhagic conditions	0.689	0.311
H18 Other disorders of cornea	0.689	0.311
Q60-Q64 Congenital malformations of the urinary system	0.689	0.311
C83 Diffuse non-Hodgkin's lymphoma	0.689	0.311
D55-D59 Haemolytic anaemias	0.688	0.312
I87 Other disorders of veins	0.688	0.312
D33 Benign neoplasm of brain and other parts of central nervous system	0.687	0.313
H35.6 Retinal haemorrhage	0.686	0.313
I88 Nonspecific lymphadenitis	0.686	0.314
T92 Sequelae of injuries of upper limb	0.686	0.314
R86 Abnormal findings in specimens from male genital organs	0.684	0.316
K64 Haemorrhoids and perianal venous thrombosis	0.684	0.316
I67.7 Cerebral arteritis, not elsewhere classified	0.684	0.316
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.684	0.316
I67.5 Moyamoya disease	0.684	0.316
I67.4 Hypertensive encephalopathy	0.684	0.316
I67.3 Progressive vascular leukoencephalopathy	0.684	0.316
K10 Other diseases of jaws	0.684	0.316
K03 Other diseases of hard tissues of teeth	0.684	0.316
H35.0 Background retinopathy and retinal vascular changes	0.683	0.317
R45 Symptoms and signs involving emotional state	0.683	0.317
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.682	0.317
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.682	0.318
I84.3 External thrombosed haemorrhoids	0.682	0.318
N18.2 Chronic kidney disease, stage 2	0.681	0.319
N40 Hyperplasia of prostate	0.680	0.320
I45.6 Preexcitation syndrome	0.680	0.320
N42 Other disorders of prostate	0.680	0.320
M46 Other inflammatory spondylopathies	0.680	0.320
H35.7 Separation of retinal layers	0.680	0.320
S90-S99 Injuries to the ankle and foot	0.679	0.321
M19 Other arthrosis	0.679	0.321
Q38-Q45 Other congenital malformations of the digestive system	0.678	0.322
I45.9 Conduction disorder, unspecified	0.678	0.322
E40-E46 Malnutrition	0.676	0.324
R06 Abnormalities of breathing	0.676	0.324
I84.7 Unspecified thrombosed haemorrhoids	0.676	0.324
T86.1 Kidney transplant failure and rejection	0.675	0.325
I42.9 Cardiomyopathy, unspecified	0.675	0.325
I77.1 Stricture of artery	0.675	0.325
L29.9 Pruritus, unspecified	0.675	0.325
I45.8 Other specified conduction disorders	0.675	0.325
I45.4 Nonspecific intraventricular block	0.675	0.325
I45.3 Trifascicular block	0.675	0.325
I45.2 Bifascicular block	0.675	0.325
I45.0 Right fascicular block	0.675	0.325
L92 Granulomatous disorders of skin and subcutaneous tissue	0.674	0.326
C34.8 Overlapping lesion of bronchus and lung	0.674	0.326
C34.0 Main bronchus	0.674	0.326
K07 Dentofacial anomalies [including malocclusion]	0.674	0.326
D67 Hereditary factor IX deficiency	0.673	0.327
D66 Hereditary factor VIII deficiency	0.673	0.327
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.673	0.327
H43-H45 Disorders of vitreous body and globe	0.673	0.327
K00.6 Disturbances in tooth eruption	0.672	0.327
D35.0 Adrenal gland	0.671	0.329
I13 Hypertensive heart and renal disease	0.671	0.329
I11 Hypertensive heart disease	0.671	0.329
Q80-Q89 Other congenital malformations	0.670	0.330
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.669	0.331
I51.6 Cardiovascular disease, unspecified	0.668	0.332
I51.5 Myocardial degeneration	0.668	0.332
I51.4 Myocarditis, unspecified	0.668	0.332
I51.3 Intracardiac thrombosis, not elsewhere classified	0.668	0.332
I51.2 Rupture of papillary muscle, not elsewhere classified	0.668	0.332
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.668	0.332
I51.0 Cardiac septal defect, acquired	0.668	0.332
H20 Iridocyclitis	0.667	0.333
N20-N23 Urolithiasis	0.667	0.333
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.667	0.333
O44 Placenta praevia	0.666	0.334
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.666	0.334
K93 Disorders of other digestive organs in diseases classified elsewhere	0.665	0.335
M53 Other dorsopathies, not elsewhere classified	0.665	0.335
S70-S79 Injuries to the hip and thigh	0.665	0.335
M43 Other deforming dorsopathies	0.664	0.336
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.664	0.336
E85 Amyloidosis	0.663	0.337
E84 Cystic fibrosis	0.663	0.337
E79 Disorders of purine and pyrimidine metabolism	0.663	0.337
E77 Disorders of glycoprotein metabolism	0.663	0.337
E76 Disorders of glycosaminoglycan metabolism	0.663	0.337
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.663	0.337
E74 Other disorders of carbohydrate metabolism	0.663	0.337
E73 Lactose intolerance	0.663	0.337
E72 Other disorders of amino-acid metabolism	0.663	0.337
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.663	0.337
E70 Disorders of aromatic amino-acid metabolism	0.663	0.337
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.663	0.337
I82 Other venous embolism and thrombosis	0.663	0.337
K14 Diseases of tongue	0.663	0.337
D23.6 Skin of upper limb, including shoulder	0.663	0.337
G93 Other disorders of brain	0.662	0.338
D60-D64 Aplastic and other anaemias	0.662	0.338
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.661	0.338
D68.6 Other Thrombophilia	0.661	0.338
D68.4 Acquired coagulation factor deficiency	0.661	0.338
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.661	0.338
D68.1 Hereditary factor XI deficiency	0.661	0.338
D68.0 Von Willebrand's disease	0.661	0.338
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.661	0.339
E87.4 Mixed disorder of acid-base balance	0.661	0.339
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.660	0.340
K05 Gingivitis and periodontal diseases	0.660	0.340
O32 Maternal care for known or suspected malpresentation of foetus	0.660	0.340
T90 Sequelae of injuries of head	0.658	0.342
C09 Malignant neoplasm of tonsil	0.658	0.342
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.656	0.344
H33 Retinal detachments and breaks	0.656	0.344
R87.6 Abnormal cytological findings	0.655	0.345
I44.3 Other and unspecified atrioventricular block	0.655	0.345
K62.2 Anal prolapse	0.654	0.345
R00 Abnormalities of heart beat	0.655	0.345
K72.9 Hepatic failure, unspecified	0.654	0.346
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.654	0.346
L29.0 Pruritus ani	0.654	0.346
M86 Osteomyelitis	0.654	0.346
K76.0 Fatty (change of) liver, not elsewhere classified	0.653	0.347
M45 Ankylosing spondylitis	0.653	0.347
L98.7 Excessive and redundant skin and subcutaneous tissue	0.653	0.347
L98.6 Other infiltrative disorders of skin and subcutaneous tissue	0.653	0.347
L98.5 Mucinosis of skin	0.653	0.347
L98.3 Eosinophilic cellulitis [Wells]	0.653	0.347
L98.2 Febrile neutrophilic dermatosis [Sweet]	0.653	0.347
L98.1 Factitial dermatitis	0.653	0.347
T87 Complications peculiar to reattachment and amputation	0.652	0.348
M50.0 Cervical disk disorder with myelopathy	0.652	0.348
M18 Arthrosis of first carpometacarpal joint	0.651	0.349
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.650	0.350
L25 Unspecified contact dermatitis	0.650	0.350
L24 Irritant contact dermatitis	0.650	0.350
L23 Allergic contact dermatitis	0.650	0.350
L21 Seborrhoeic dermatitis	0.650	0.350
L20 Atopic dermatitis	0.650	0.350
L26 Exfoliative dermatitis	0.650	0.350
L22 Diaper [napkin] dermatitis	0.650	0.350
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.650	0.350
T88 Other complications of surgical and medical care, not elsewhere classified	0.650	0.350
D18.0 Haemangioma, any site	0.650	0.350
H32 Chorioretinal disorders in diseases classified elsewhere	0.649	0.350
H31 Other disorders of choroid	0.649	0.350
H30 Chorioretinal inflammation	0.649	0.350
K55.2 Angiodysplasia of colon	0.649	0.351
K90 Intestinal malabsorption	0.649	0.351
D00-D09 In situ neoplasms	0.649	0.351
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.649	0.351
K76.7 Hepatorenal syndrome	0.649	0.351
K76.5 Hepatic veno-occlusive disease	0.649	0.351
K76.4 Peliosis hepatis	0.649	0.351
K76.3 Infarction of liver	0.649	0.351
K76.2 Central haemorrhagic necrosis of liver	0.649	0.351
K76.1 Chronic passive congestion of liver	0.649	0.351
N48.2 Other inflammatory disorders of penis	0.648	0.351
R82 Other abnormal findings in urine	0.648	0.352
M54.9 Dorsalgia, unspecified	0.647	0.353

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations