TreeWAS – Variant ID: rs75493593

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
# Top node	0.998	0.002	0.000
Chapter XIV Diseases of the genitourinary system	0.991	0.009	0.000
Chapter XXI Factors influencing health status and contact with health services	0.985	0.015	0.000
Chapter IX Diseases of the circulatory system	0.978	0.022	0.000
Z00-Z13 Persons encountering health services for examination and investigation	0.975	0.025	0.000
Chapter V Mental and behavioural disorders	0.973	0.027	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.964	0.036	0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.960	0.040	0.000
Chapter II Neoplasms	0.951	0.049	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.951	0.049	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.933	0.067	0.000
I84 Haemorrhoids	0.928	0.072	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.926	0.074	0.000
N60-N64 Disorders of breast	0.921	0.079	0.000
Z12 Special screening examination for neoplasms	0.914	0.086	0.000
Z13 Special screening examination for other diseases and disorders	0.905	0.095	0.000
F30-F39 Mood [affective] disorders	0.899	0.101	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.896	0.104	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.884	0.116	0.000
I83 Varicose veins of lower extremities	0.878	0.122	0.000
Z37 Outcome of delivery	0.876	0.124	0.000
I84.8 Unspecified haemorrhoids with other complications	0.875	0.125	0.000
S80-S89 Injuries to the knee and lower leg	0.870	0.130	0.000
N80-N98 Noninflammatory disorders of female genital tract	0.867	0.133	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.858	0.142	0.000
N63 Unspecified lump in breast	0.854	0.146	0.000
O60-O75 Complications of labour and delivery	0.853	0.147	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.852	0.148	0.000
N40-N51 Diseases of male genital organs	0.849	0.151	0.000
Z12.1 Special screening examination for neoplasm of intestinal tract	0.847	0.153	0.000
C60-C63 Malignant neoplasms of male genital organs	0.846	0.154	0.000
F32 Depressive episode	0.842	0.158	0.000
Z03 Medical observation and evaluation for suspected diseases and conditions	0.839	0.161	0.000
Z35 Supervision of high-risk pregnancy	0.836	0.164	0.000
Z02 Examination and encounter for administrative purposes	0.827	0.173	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.822	0.177	0.000
N70-N77 Inflammatory diseases of female pelvic organs	0.819	0.181	0.000
Z37.0 Single live birth	0.816	0.184	0.000
F10 Mental and behavioural disorders due to use of alcohol	0.814	0.186	0.000
S82 Fracture of lower leg, including ankle	0.809	0.191	0.000
I73 Other peripheral vascular diseases	0.805	0.195	0.000
F32.9 Depressive episode, unspecified	0.800	0.200	0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.797	0.203	0.000
I84.2 Internal haemorrhoids without complication	0.797	0.203	0.000
N20-N23 Urolithiasis	0.792	0.208	0.000
Chapter VII Diseases of the eye and adnexa	0.791	0.209	0.000
N87 Dysplasia of cervix uteri	0.790	0.209	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.784	0.216	0.000
O80-O84 Delivery	0.776	0.224	0.000
Z39 Postpartum care and examination	0.775	0.225	0.000
I84.1 Internal haemorrhoids with other complications	0.774	0.226	0.000
I60-I69 Cerebrovascular diseases	0.773	0.227	0.000
D60-D64 Aplastic and other anaemias	0.770	0.230	0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.770	0.230	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.769	0.231	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.769	0.231	0.000
Z34 Supervision of normal pregnancy	0.766	0.234	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.764	0.236	0.000
I05-I09 Chronic rheumatic heart diseases	0.760	0.240	0.000
C15-C26 Malignant neoplasms of digestive organs	0.760	0.240	0.000
N17-N19 Renal failure	0.760	0.240	0.000
Z13.9 Special screening examination, unspecified	0.758	0.242	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.755	0.245	0.000
O70 Perineal laceration during delivery	0.754	0.246	0.000
N80 Endometriosis	0.754	0.246	0.000
C61 Malignant neoplasm of prostate	0.754	0.246	0.000
Z12.8 Special screening examination for neoplasm of other sites	0.748	0.252	0.000
Chapter XXII Codes for special purposes	0.746	0.253	0.000
Chapter VIII Diseases of the ear and mastoid process	0.744	0.256	0.000
N30-N39 Other diseases of urinary system	0.744	0.256	0.000
D69 Purpura and other haemorrhagic conditions	0.743	0.257	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.742	0.258	0.000
I26 Pulmonary embolism	0.742	0.258	0.000
S20-S29 Injuries to the thorax	0.739	0.261	0.000
Z13.6 Special screening examination for cardiovascular disorders	0.738	0.262	0.000
S60-S69 Injuries to the wrist and hand	0.737	0.263	0.000
I73.9 Peripheral vascular disease, unspecified	0.737	0.263	0.000
Z08 Follow-up examination after treatment for malignant neoplasm	0.734	0.266	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.733	0.267	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.732	0.268	0.000
N43 Hydrocele and spermatocele	0.730	0.270	0.000
I84.3 External thrombosed haemorrhoids	0.728	0.272	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.726	0.273	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.725	0.275	0.000
Z11 Special screening examination for infectious and parasitic diseases	0.725	0.275	0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.723	0.277	0.000
N93 Other abnormal uterine and vaginal bleeding	0.722	0.278	0.000
N92 Excessive, frequent and irregular menstruation	0.722	0.278	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.721	0.279	0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle	0.721	0.279	0.000
Z03.8 Observation for other suspected diseases and conditions	0.721	0.279	0.000
Z02.8 Other examinations for administrative purposes	0.721	0.279	0.000
N25-N29 Other disorders of kidney and ureter	0.720	0.280	0.000
N00-N08 Glomerular diseases	0.718	0.281	0.000
F10.1 Harmful use	0.718	0.282	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.716	0.283	0.000
T66-T78 Other and unspecified effects of external causes	0.716	0.284	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.715	0.284	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.715	0.284	0.000
C64-C68 Malignant neoplasms of urinary tract	0.715	0.285	0.000
I80 Phlebitis and thrombophlebitis	0.715	0.285	0.000
I84.6 Residual haemorrhoidal skin tags	0.714	0.286	0.000
N10-N16 Renal tubulo-interstitial diseases	0.713	0.287	0.000
S81 Open wound of lower leg	0.710	0.290	0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.707	0.293	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.706	0.294	0.000
I70 Atherosclerosis	0.703	0.297	0.000
O72 Postpartum haemorrhage	0.702	0.298	0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.701	0.299	0.000
I00-I02 Acute rheumatic fever	0.701	0.299	0.000
Z36 Antenatal screening	0.700	0.300	0.000
Z10 Routine general health check-up of defined subpopulation	0.699	0.301	0.000
S82.8 Fractures of other parts of lower leg	0.699	0.301	0.000
N60 Benign mammary dysplasia	0.698	0.301	0.000
N61 Inflammatory disorders of breast	0.698	0.302	0.000
F99-F99 Unspecified mental disorder	0.698	0.302	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.698	0.302	0.000
F80-F89 Disorders of psychological development	0.698	0.302	0.000
F70-F79 Mental retardation	0.698	0.302	0.000
F60-F69 Disorders of adult personality and behaviour	0.698	0.302	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.698	0.302	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.698	0.302	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.698	0.302	0.000
N99-N99 Other disorders of the genitourinary system	0.697	0.303	0.000
O00-O08 Pregnancy with abortive outcome	0.695	0.305	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.695	0.305	0.000
I83.1 Varicose veins of lower extremities with inflammation	0.692	0.308	0.000
Z33 Pregnant state, incidental	0.691	0.309	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.691	0.309	0.000
I88 Nonspecific lymphadenitis	0.691	0.309	0.000
I87 Other disorders of veins	0.691	0.309	0.000
I86 Varicose veins of other sites	0.691	0.309	0.000
I85 Oesophageal varices	0.691	0.309	0.000
I82 Other venous embolism and thrombosis	0.691	0.309	0.000
I81 Portal vein thrombosis	0.691	0.309	0.000
Z38 Liveborn infants according to place of birth	0.688	0.312	0.000
Z32 Pregnancy examination and test	0.688	0.312	0.000
Z31 Procreative management	0.688	0.312	0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.686	0.314	0.000
N48 Other disorders of penis	0.684	0.316	0.000
N42 Other disorders of prostate	0.683	0.317	0.000
Z03.1 Observation for suspected malignant neoplasm	0.683	0.317	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.682	0.318	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.682	0.318	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.682	0.318	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.682	0.318	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.682	0.318	0.000
O85-O92 Complications predominantly related to the puerperium	0.682	0.318	0.000
Z30 Contraceptive management	0.678	0.322	0.000
I77 Other disorders of arteries and arterioles	0.678	0.322	0.000
F10.2 Dependence syndrome	0.678	0.322	0.000
I78 Diseases of capillaries	0.676	0.324	0.000
C51-C58 Malignant neoplasms of female genital organs	0.676	0.324	0.000
N90 Other noninflammatory disorders of vulva and perineum	0.672	0.327	0.000
D80-D89 Certain disorders involving the immune mechanism	0.669	0.331	0.000
D55-D59 Haemolytic anaemias	0.669	0.331	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.667	0.332	0.000
F31 Bipolar affective disorder	0.667	0.333	0.000
C92 Myeloid leukaemia	0.667	0.333	0.000
N87.0 Mild cervical dysplasia	0.667	0.333	0.000
N23 Unspecified renal colic	0.665	0.335	0.000
I84.7 Unspecified thrombosed haemorrhoids	0.665	0.335	0.000
I84.4 External haemorrhoids with other complications	0.665	0.335	0.000
I84.0 Internal thrombosed haemorrhoids	0.665	0.335	0.000
T79-T79 Certain early complications of trauma	0.664	0.336	0.000
T33-T35 Frostbite	0.664	0.336	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.664	0.336	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.664	0.336	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.664	0.336	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.664	0.336	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.664	0.336	0.000
T00-T07 Injuries involving multiple body regions	0.664	0.336	0.000
S90-S99 Injuries to the ankle and foot	0.664	0.336	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.664	0.336	0.000
S10-S19 Injuries to the neck	0.664	0.336	0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.663	0.337	0.000
N64 Other disorders of breast	0.661	0.339	0.000
O70.0 First degree perineal laceration during delivery	0.660	0.340	0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.658	0.342	0.000
N62 Hypertrophy of breast	0.658	0.342	0.000
N87.9 Dysplasia of cervix uteri, unspecified	0.657	0.343	0.000
F17 Mental and behavioural disorders due to use of tobacco	0.656	0.344	0.000
S82.6 Fracture of lateral malleolus	0.656	0.344	0.000
Z12.9 Special screening examination for neoplasm, unspecified	0.655	0.344	0.000
Z12.6 Special screening examination for neoplasm of bladder	0.655	0.344	0.000
Z12.5 Special screening examination for neoplasm of prostate	0.655	0.344	0.000
Z12.4 Special screening examination for neoplasm of cervix	0.655	0.344	0.000
Z12.3 Special screening examination for neoplasm of breast	0.655	0.344	0.000
Z12.2 Special screening examination for neoplasm of respiratory organs	0.655	0.344	0.000
Z12.0 Special screening examination for neoplasm of stomach	0.655	0.344	0.000
D45 Polycythaemia vera	0.655	0.345	0.000
N93.8 Other specified abnormal uterine and vaginal bleeding	0.654	0.346	0.000
I27 Other pulmonary heart diseases	0.654	0.346	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.654	0.346	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.653	0.346	0.000
D64 Other anaemias	0.653	0.347	0.000
S40-S49 Injuries to the shoulder and upper arm	0.653	0.347	0.000
D50-D53 Nutritional anaemias	0.653	0.347	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.652	0.348	0.000
C62 Malignant neoplasm of testis	0.651	0.349	0.000
O80 Single spontaneous delivery	0.651	0.349	0.000
N92.0 Excessive and frequent menstruation with regular cycle	0.651	0.349	0.000
Z35.5 Supervision of elderly primigravida	0.651	0.349	0.000
Z13.8 Special screening examination for other specified diseases and disorders	0.648	0.351	0.000
Z13.7 Special screening examination for congenital malformations, deformations and chromosomal abnormalities	0.648	0.351	0.000
Z13.5 Special screening examination for eye and ear disorders	0.648	0.351	0.000
Z13.4 Special screening examination for certain developmental disorders in childhood	0.648	0.351	0.000
Z13.3 Special screening examination for mental and behavioural disorders	0.648	0.351	0.000
Z13.2 Special screening examination for nutritional disorders	0.648	0.351	0.000
Z13.1 Special screening examination for diabetes mellitus	0.648	0.351	0.000
I74 Arterial embolism and thrombosis	0.647	0.353	0.000
H53-H54 Visual disturbances and blindness	0.646	0.354	0.000
H02 Other disorders of eyelid	0.645	0.355	0.000
F38 Other mood [affective] disorders	0.645	0.355	0.000
F34 Persistent mood [affective] disorders	0.645	0.355	0.000
F33 Recurrent depressive disorder	0.645	0.355	0.000
F30 Manic episode	0.645	0.355	0.000
F39 Unspecified mood [affective] disorder	0.645	0.355	0.000
N43.3 Hydrocele, unspecified	0.645	0.355	0.000
Chapter XX External causes of morbidity and mortality	0.644	0.356	0.000
D70 Agranulocytosis	0.643	0.357	0.000
Z39.0 Care and examination immediately after delivery	0.642	0.358	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.642	0.358	0.000
I72 Other aneurysm	0.642	0.358	0.000
N72 Inflammatory disease of cervix uteri	0.640	0.360	0.000
D10-D36 Benign neoplasms	0.639	0.361	0.000
N47 Redundant prepuce, phimosis and paraphimosis	0.639	0.361	0.000
O16 Unspecified maternal hypertension	0.639	0.361	0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.634	0.366	0.000
F18 Mental and behavioural disorders due to use of volatile solvents	0.634	0.366	0.000
F16 Mental and behavioural disorders due to use of hallucinogens	0.634	0.366	0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.634	0.366	0.000
F14 Mental and behavioural disorders due to use of cocaine	0.634	0.366	0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.634	0.366	0.000
F12 Mental and behavioural disorders due to use of cannabinoids	0.634	0.366	0.000
F11 Mental and behavioural disorders due to use of opioids	0.634	0.366	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.632	0.368	0.000
N75 Diseases of Bartholin's gland	0.630	0.370	0.000
N35 Urethral stricture	0.630	0.370	0.000
N30 Cystitis	0.630	0.370	0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.630	0.370	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.630	0.370	0.000
Z37.9 Outcome of delivery unspecified	0.628	0.372	0.000
Z37.7 Other multiple births, all stillborn	0.628	0.372	0.000
Z37.6 Other multiple births, some liveborn	0.628	0.372	0.000
Z37.5 Other multiple births, all liveborn	0.628	0.372	0.000
Z37.4 Twins, both stillborn	0.628	0.372	0.000
Z37.3 Twins, one liveborn and one stillborn	0.628	0.372	0.000
Z37.2 Twins, both liveborn	0.628	0.372	0.000
Z37.1 Single stillbirth	0.628	0.372	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.628	0.372	0.000
Z34.8 Supervision of other normal pregnancy	0.628	0.372	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.628	0.372	0.000
C18 Malignant neoplasm of colon	0.627	0.372	0.000
N80.8 Other endometriosis	0.627	0.373	0.000
N45 Orchitis and epididymitis	0.627	0.373	0.000
Z03.5 Observation for other suspected cardiovascular diseases	0.626	0.374	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.625	0.375	0.000
S82.5 Fracture of medial malleolus	0.625	0.375	0.000
S89 Other and unspecified injuries of lower leg	0.624	0.376	0.000
S88 Traumatic amputation of lower leg	0.624	0.376	0.000
S87 Crushing injury of lower leg	0.624	0.376	0.000
S86 Injury of muscle and tendon at lower leg level	0.624	0.376	0.000
S85 Injury of blood vessels at lower leg level	0.624	0.376	0.000
S84 Injury of nerves at lower leg level	0.624	0.376	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.624	0.376	0.000
S80 Superficial injury of lower leg	0.624	0.376	0.000
N73 Other female pelvic inflammatory diseases	0.623	0.376	0.000
S70-S79 Injuries to the hip and thigh	0.623	0.377	0.000
N87.1 Moderate cervical dysplasia	0.623	0.377	0.000
N98 Complications associated with artificial fertilisation	0.622	0.378	0.000
N91 Absent, scanty and rare menstruation	0.622	0.378	0.000
N82 Fistulae involving female genital tract	0.622	0.378	0.000
N96 Habitual aborter	0.622	0.378	0.000
Z04 Examination and observation for other reasons	0.621	0.378	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.621	0.379	0.000
S00-S09 Injuries to the head	0.621	0.379	0.000
S82.3 Fracture of lower end of tibia	0.621	0.379	0.000
S82.80 Fractures of other parts of lower leg (closed)	0.620	0.380	0.000
F10.0 Acute intoxication	0.619	0.381	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.618	0.382	0.000
N94.1 Dyspareunia	0.618	0.382	0.000
F41 Other anxiety disorders	0.617	0.383	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.615	0.385	0.000
C95 Leukaemia of unspecified cell type	0.615	0.385	0.000
C94 Other leukaemias of specified cell type	0.615	0.385	0.000
C93 Monocytic leukaemia	0.615	0.385	0.000
C88 Malignant immunoproliferative diseases	0.615	0.385	0.000
C86 Other specified types of T/NK-cell lymphoma	0.615	0.385	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.615	0.385	0.000
C81 Hodgkin's disease	0.615	0.385	0.000
C91 Lymphoid leukaemia	0.615	0.385	0.000
I69 Sequelae of cerebrovascular disease	0.615	0.385	0.000
D69.6 Thrombocytopenia, unspecified	0.613	0.387	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.611	0.389	0.000
O74 Complications of anaesthesia during labour and delivery	0.611	0.389	0.000
O73 Retained placenta and membranes, without haemorrhage	0.611	0.389	0.000
O71 Other obstetric trauma	0.611	0.389	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.611	0.389	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.611	0.389	0.000
O66 Other obstructed labour	0.611	0.389	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.611	0.389	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.611	0.389	0.000
O62 Abnormalities of forces of labour	0.611	0.389	0.000
O61 Failed induction of labour	0.611	0.389	0.000
O60 Preterm delivery	0.611	0.389	0.000
I28 Other diseases of pulmonary vessels	0.611	0.389	0.000
N51 Disorders of male genital organs in diseases classified elsewhere	0.609	0.391	0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.609	0.391	0.000
N46 Male infertility	0.609	0.391	0.000
N44 Torsion of testis	0.609	0.391	0.000
I67 Other cerebrovascular diseases	0.608	0.392	0.000
C63 Malignant neoplasm of other and unspecified male genital organs	0.607	0.393	0.000
C60 Malignant neoplasm of penis	0.607	0.393	0.000
N89 Other noninflammatory disorders of vagina	0.607	0.393	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.604	0.395	0.000
F32.8 Other depressive episodes	0.603	0.396	0.000
F32.3 Severe depressive episode with psychotic symptoms	0.603	0.396	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.603	0.396	0.000
F32.1 Moderate depressive episode	0.603	0.396	0.000
F32.0 Mild depressive episode	0.603	0.396	0.000
N92.3 Ovulation bleeding	0.603	0.397	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.602	0.398	0.000
S82.1 Fracture of upper end of tibia	0.601	0.398	0.000
Z03.9 Observation for suspected disease or condition, unspecified	0.601	0.398	0.000
Z03.6 Observation for suspected toxic effect from ingested substance	0.601	0.398	0.000
Z03.3 Observation for suspected nervous system disorder	0.601	0.398	0.000
Z03.2 Observation for suspected mental and behavioural disorders	0.601	0.398	0.000
Z03.0 Observation for suspected tuberculosis	0.601	0.398	0.000
N50 Other disorders of male genital organs	0.600	0.400	0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.600	0.400	0.000
Z35.9 Supervision of high-risk pregnancy, unspecified	0.599	0.400	0.000
Z35.8 Supervision of other high-risk pregnancies	0.599	0.400	0.000
Z35.7 Supervision of high-risk pregnancy due to social problems	0.599	0.400	0.000
Z35.6 Supervision of very young primigravida	0.599	0.400	0.000
Z35.4 Supervision of pregnancy with grand multiparity	0.599	0.400	0.000
Z35.3 Supervision of pregnancy with history of insufficient antenatal care	0.599	0.400	0.000
Z35.1 Supervision of pregnancy with history of abortive outcome	0.599	0.400	0.000
Z35.0 Supervision of pregnancy with history of infertility	0.599	0.400	0.000
I71 Aortic aneurysm and dissection	0.599	0.401	0.000
I07 Rheumatic tricuspid valve diseases	0.596	0.404	0.000
O63 Long labour	0.595	0.405	0.000
N80.1 Endometriosis of ovary	0.595	0.405	0.000
S81.9 Open wound of lower leg, part unspecified	0.595	0.405	0.000
O72.1 Other immediate postpartum haemorrhage	0.594	0.406	0.000
O70.1 Second degree perineal laceration during delivery	0.594	0.406	0.000
N80.0 Endometriosis of uterus	0.594	0.406	0.000
T90 Sequelae of injuries of head	0.593	0.407	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.593	0.407	0.000
Z02.9 Examination for administrative purposes, unspecified	0.593	0.407	0.000
Z02.7 Issue of medical certificate	0.593	0.407	0.000
Z02.6 Examination for insurance purposes	0.593	0.407	0.000
Z02.5 Examination for participation in sport	0.593	0.407	0.000
Z02.4 Examination for driving licence	0.593	0.407	0.000
Z02.3 Examination for recruitment to armed forces	0.593	0.407	0.000
Z02.2 Examination for admission to residential institution	0.593	0.407	0.000
Z02.1 Pre-employment examination	0.593	0.407	0.000
Z02.0 Examination for admission to educational institution	0.593	0.407	0.000
H02.8 Other specified disorders of eyelid	0.591	0.409	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.591	0.409	0.000
S61 Open wound of wrist and hand	0.591	0.409	0.000
D68 Other coagulation defects	0.590	0.410	0.000
D67 Hereditary factor IX deficiency	0.590	0.410	0.000
D66 Hereditary factor VIII deficiency	0.590	0.410	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.590	0.410	0.000
D00-D09 In situ neoplasms	0.589	0.411	0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere	0.587	0.413	0.000
N76 Other inflammation of vagina and vulva	0.587	0.413	0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere	0.587	0.413	0.000
N71 Inflammatory disease of uterus, except cervix	0.587	0.413	0.000
N70 Salpingitis and oophoritis	0.587	0.413	0.000
I73.0 Raynaud's syndrome	0.586	0.414	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.584	0.415	0.000
F10.9 Unspecified mental and behavioural disorder	0.584	0.416	0.000
F10.8 Other mental and behavioural disorders	0.584	0.416	0.000
F10.7 Residual and late-onset psychotic disorder	0.584	0.416	0.000
F10.6 Amnesic syndrome	0.584	0.416	0.000
F10.5 Psychotic disorder	0.584	0.416	0.000
F10.4 Withdrawal state with delirium	0.584	0.416	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.582	0.418	0.000
O20 Haemorrhage in early pregnancy	0.581	0.419	0.000
H43-H45 Disorders of vitreous body and globe	0.580	0.420	0.000
N17 Acute renal failure	0.580	0.420	0.000
S82.9 Fracture of lower leg, part unspecified	0.580	0.420	0.000
S82.7 Multiple fractures of lower leg	0.580	0.420	0.000
S82.4 Fracture of fibula alone	0.580	0.420	0.000
S82.2 Fracture of shaft of tibia	0.580	0.420	0.000
S82.0 Fracture of patella	0.580	0.420	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.580	0.420	0.000
N83.2 Other and unspecified ovarian cysts	0.579	0.421	0.000
Z70-Z76 Persons encountering health services in other circumstances	0.578	0.422	0.000
C16 Malignant neoplasm of stomach	0.577	0.423	0.000
I60 Subarachnoid haemorrhage	0.577	0.423	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.577	0.423	0.000
I73.8 Other specified peripheral vascular diseases	0.577	0.423	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.577	0.423	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.576	0.424	0.000
Z30.1 Insertion of (intra-uterine) contraceptive device	0.576	0.424	0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.575	0.425	0.000
H60-H62 Diseases of external ear	0.574	0.426	0.000
F10.3 Withdrawal state	0.573	0.427	0.000
N21 Calculus of lower urinary tract	0.572	0.428	0.000
D64.9 Anaemia, unspecified	0.569	0.431	0.000
N93.0 Postcoital and contact bleeding	0.569	0.431	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.569	0.431	0.000
N22 Calculus of urinary tract in diseases classified elsewhere	0.568	0.432	0.000
H55-H59 Other disorders of eye and adnexa	0.567	0.433	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.567	0.433	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.567	0.433	0.000
H10-H13 Disorders of conjunctiva	0.567	0.433	0.000
N41 Inflammatory diseases of prostate	0.567	0.433	0.000
N87.2 Severe cervical dysplasia, not elsewhere classified	0.567	0.433	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.566	0.434	0.000
C73 Malignant neoplasm of thyroid gland	0.565	0.435	0.000
N48.1 Balanoposthitis	0.565	0.435	0.000
T78 Adverse effects, not elsewhere classified	0.565	0.435	0.000
N32 Other disorders of bladder	0.565	0.435	0.000
S50-S59 Injuries to the elbow and forearm	0.564	0.435	0.001
I70.2 Atherosclerosis of arteries of the extremities	0.564	0.436	0.000
H80-H83 Diseases of inner ear	0.564	0.436	0.000
O04 Medical abortion	0.563	0.437	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.562	0.437	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.562	0.437	0.000
D46 Myelodysplastic syndromes	0.562	0.437	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.562	0.437	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.562	0.437	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.562	0.437	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.562	0.437	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.562	0.437	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.562	0.437	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.562	0.437	0.000
O80.0 Spontaneous vertex delivery	0.561	0.439	0.000
F40 Phobic anxiety disorders	0.561	0.439	0.000
C15 Malignant neoplasm of oesophagus	0.557	0.443	0.000
O84 Multiple delivery	0.557	0.443	0.000
O83 Other assisted single delivery	0.557	0.443	0.000
O82 Single delivery by Caesarean section	0.557	0.443	0.000
O81 Single delivery by forceps and vacuum extractor	0.557	0.443	0.000
N88 Other noninflammatory disorders of cervix uteri	0.556	0.444	0.000
N42.8 Other specified disorders of prostate	0.556	0.444	0.000
N19 Unspecified renal failure	0.556	0.444	0.000
Z39.2 Routine postpartum follow-up	0.555	0.444	0.000
Z39.1 Care and examination of lactating mother	0.555	0.444	0.000
I08 Multiple valve diseases	0.555	0.444	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.554	0.446	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.554	0.446	0.000
I62 Other nontraumatic intracranial haemorrhage	0.554	0.446	0.000
I61 Intracerebral haemorrhage	0.554	0.446	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.552	0.448	0.000
D61 Other aplastic anaemias	0.552	0.448	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.552	0.448	0.000
D62 Acute posthaemorrhagic anaemia	0.552	0.448	0.000
C79 Secondary malignant neoplasm of other sites	0.552	0.448	0.000
H65-H75 Diseases of middle ear and mastoid	0.552	0.448	0.000
F48 Other neurotic disorders	0.552	0.448	0.000
F45 Somatoform disorders	0.552	0.448	0.000
F44 Dissociative [conversion] disorders	0.552	0.448	0.000
F43 Reaction to severe stress, and adjustment disorders	0.552	0.448	0.000
F42 Obsessive-compulsive disorder	0.552	0.448	0.000
O15 Eclampsia	0.551	0.448	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.551	0.448	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.551	0.448	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.551	0.448	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.551	0.448	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.551	0.448	0.000
N18 Chronic renal failure	0.550	0.450	0.000
Z34.9 Supervision of normal pregnancy, unspecified	0.549	0.450	0.000
Z34.0 Supervision of normal first pregnancy	0.549	0.450	0.000
Chapter X Diseases of the respiratory system	0.549	0.451	0.000
N35.9 Urethral stricture, unspecified	0.549	0.451	0.000
C34 Malignant neoplasm of bronchus and lung	0.548	0.452	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.548	0.452	0.000
D75 Other diseases of blood and blood-forming organs	0.548	0.452	0.000
D74 Methaemoglobinaemia	0.548	0.452	0.000
D73 Diseases of spleen	0.548	0.452	0.000
D72 Other disorders of white blood cells	0.548	0.452	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.548	0.452	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.548	0.452	0.000
S82.60 Fracture of lateral malleolus (closed)	0.546	0.454	0.000
Z11.0 Special screening examination for intestinal infectious diseases	0.545	0.454	0.000
S62 Fracture at wrist and hand level	0.545	0.455	0.000
I09 Other rheumatic heart diseases	0.545	0.455	0.000
I06 Rheumatic aortic valve diseases	0.545	0.455	0.000
I05 Rheumatic mitral valve diseases	0.545	0.455	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.545	0.455	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.545	0.455	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.545	0.455	0.000
C21 Malignant neoplasm of anus and anal canal	0.545	0.455	0.000
C17 Malignant neoplasm of small intestine	0.545	0.455	0.000
C23 Malignant neoplasm of gallbladder	0.545	0.455	0.000
C25 Malignant neoplasm of pancreas	0.544	0.456	0.000
C85.1 B-cell lymphoma, unspecified	0.544	0.456	0.000
C67 Malignant neoplasm of bladder	0.544	0.456	0.000
N97 Female infertility	0.543	0.456	0.000
H53 Visual disturbances	0.543	0.457	0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle	0.542	0.458	0.000
O29 Complications of anaesthesia during pregnancy	0.541	0.459	0.000
O28 Abnormal findings on antenatal screening of mother	0.541	0.459	0.000
O24 Diabetes mellitus in pregnancy	0.541	0.459	0.000
O23 Infections of genito-urinary tract in pregnancy	0.541	0.459	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations