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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75538714
log Bayes Factor = 15.783
Chromosome 20   position 55,594,141  (GRCh37) Explore rs75538714 on Ensembl!
Variant rs75538714 is part of Cluster X0277

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
Chapter II Neoplasms
0.993 0.007 0.000
Chapter XX External causes of morbidity and mortality
0.991 0.009 0.000
M45-M49 Spondylopathies
0.985 0.015 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.983 0.017 0.000
E65-E68 Obesity and other hyperalimentation
0.982 0.018 0.000
Chapter XI Diseases of the digestive system
0.981 0.019 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.980 0.020 0.000
M50-M54 Other dorsopathies
0.976 0.024 0.000
I60-I69 Cerebrovascular diseases
0.975 0.025 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.974 0.026 0.000
E10-E14 Diabetes mellitus
0.971 0.029 0.000
E66 Obesity
0.971 0.029 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.966 0.034 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.964 0.036 0.000
I51 Complications and ill-defined descriptions of heart disease
0.964 0.036 0.000
O00-O08 Pregnancy with abortive outcome
0.964 0.036 0.000
I10-I15 Hypertensive diseases
0.964 0.036 0.000
I35 Nonrheumatic aortic valve disorders
0.963 0.037 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.961 0.039 0.000
E66.8 Other obesity
0.950 0.050 0.000
C79 Secondary malignant neoplasm of other sites
0.948 0.052 0.000
I10 Essential (primary) hypertension
0.942 0.058 0.000
K81 Cholecystitis
0.942 0.058 0.000
I20-I25 Ischaemic heart diseases
0.942 0.058 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.936 0.064 0.000
M20-M25 Other joint disorders
0.932 0.068 0.000
M48 Other spondylopathies
0.931 0.068 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.929 0.071 0.000
I77 Other disorders of arteries and arterioles
0.928 0.072 0.000
M54 Dorsalgia
0.928 0.072 0.000
E11 Non-insulin-dependent diabetes mellitus
0.927 0.073 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.925 0.075 0.000
I50 Heart failure
0.921 0.079 0.000
I31 Other diseases of pericardium
0.921 0.079 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.920 0.080 0.000
K81.0 Acute cholecystitis
0.907 0.093 0.000
M47 Spondylosis
0.906 0.094 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.906 0.094 0.000
I35.0 Aortic (valve) stenosis
0.904 0.096 0.000
I69 Sequelae of cerebrovascular disease
0.903 0.097 0.000
K86 Other diseases of pancreas
0.902 0.098 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.902 0.098 0.000
O04 Medical abortion
0.900 0.100 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.900 0.100 0.000
I47 Paroxysmal tachycardia
0.900 0.100 0.000
K65-K67 Diseases of peritoneum
0.898 0.102 0.000
Y95 Nosocomial condition
0.897 0.103 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.896 0.104 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.895 0.105 0.000
M48.0 Spinal stenosis
0.894 0.106 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.892 0.108 0.000
I50.0 Congestive heart failure
0.890 0.110 0.000
I51.7 Cardiomegaly
0.890 0.110 0.000
K50-K52 Noninfective enteritis and colitis
0.889 0.111 0.000
I51.8 Other ill-defined heart diseases
0.889 0.111 0.000
I63 Cerebral infarction
0.888 0.112 0.000
S80-S89 Injuries to the knee and lower leg
0.884 0.116 0.000
I20 Angina pectoris
0.884 0.116 0.000
I26 Pulmonary embolism
0.878 0.122 0.000
I35.1 Aortic (valve) insufficiency
0.873 0.127 0.000
D10-D36 Benign neoplasms
0.870 0.130 0.000
S00-S09 Injuries to the head
0.867 0.133 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.864 0.136 0.000
E66.9 Obesity, unspecified
0.862 0.138 0.000
I42 Cardiomyopathy
0.861 0.139 0.000
I77.1 Stricture of artery
0.860 0.140 0.000
O02 Other abnormal products of conception
0.858 0.141 0.000
K50 Crohn's disease [regional enteritis]
0.856 0.144 0.000
E40-E46 Malnutrition
0.856 0.144 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.854 0.146 0.000
M05-M14 Inflammatory polyarthropathies
0.854 0.146 0.000
I20.0 Unstable angina
0.848 0.152 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.847 0.153 0.000
I65.2 Occlusion and stenosis of carotid artery
0.846 0.154 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.846 0.154 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.845 0.155 0.000
M47.9 Spondylosis, unspecified
0.845 0.155 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.844 0.156 0.000
E11.4 With neurological complications
0.843 0.157 0.000
I31.3 Pericardial effusion (noninflammatory)
0.843 0.157 0.000
K66 Other disorders of peritoneum
0.842 0.158 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.842 0.158 0.000
M50 Cervical disk disorders
0.840 0.160 0.000
M15-M19 Arthrosis
0.839 0.161 0.000
T66-T78 Other and unspecified effects of external causes
0.837 0.163 0.000
I72 Other aneurysm
0.836 0.164 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.836 0.164 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.836 0.164 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.836 0.164 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.836 0.164 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.834 0.166 0.000
K50.9 Crohn's disease, unspecified
0.832 0.168 0.000
I71 Aortic aneurysm and dissection
0.832 0.168 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.832 0.168 0.000
O04.9 Complete or unspecified, without complication
0.830 0.170 0.000
M25 Other joint disorders, not elsewhere classified
0.829 0.171 0.000
D25 Leiomyoma of uterus
0.828 0.172 0.000
E11.3 With ophthalmic complications
0.828 0.172 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.826 0.174 0.000
C34 Malignant neoplasm of bronchus and lung
0.825 0.175 0.000
M54.3 Sciatica
0.823 0.177 0.000
E10 Insulin-dependent diabetes mellitus
0.822 0.178 0.000
K82 Other diseases of gallbladder
0.820 0.180 0.000
O03 Spontaneous abortion
0.820 0.180 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.819 0.181 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.816 0.184 0.000
I38 Endocarditis, valve unspecified
0.814 0.186 0.000
T81 Complications of procedures, not elsewhere classified
0.812 0.188 0.000
M06 Other rheumatoid arthritis
0.812 0.188 0.000
M24 Other specific joint derangements
0.811 0.189 0.000
I70 Atherosclerosis
0.810 0.190 0.000
T93 Sequelae of injuries of lower limb
0.810 0.190 0.000
I05-I09 Chronic rheumatic heart diseases
0.809 0.191 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.808 0.192 0.000
M46 Other inflammatory spondylopathies
0.806 0.194 0.000
S20-S29 Injuries to the thorax
0.804 0.196 0.000
M70-M79 Other soft tissue disorders
0.803 0.197 0.000
M54.9 Dorsalgia, unspecified
0.802 0.198 0.000
K66.0 Peritoneal adhesions
0.802 0.198 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.800 0.200 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.800 0.200 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.797 0.203 0.000
S80 Superficial injury of lower leg
0.795 0.205 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.794 0.206 0.000
C51-C58 Malignant neoplasms of female genital organs
0.793 0.207 0.000
I77.6 Arteritis, unspecified
0.792 0.208 0.000
M25.7 Osteophyte
0.788 0.212 0.000
D12.2 Ascending colon
0.787 0.213 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.787 0.213 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.786 0.214 0.000
K83 Other diseases of biliary tract
0.786 0.214 0.000
K35-K38 Diseases of appendix
0.785 0.215 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.781 0.219 0.000
K12 Stomatitis and related lesions
0.780 0.220 0.000
L50-L54 Urticaria and erythema
0.780 0.220 0.000
I47.2 Ventricular tachycardia
0.779 0.221 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.778 0.222 0.000
M35 Other systemic involvement of connective tissue
0.775 0.225 0.000
K85 Acute pancreatitis
0.774 0.225 0.000
I30 Acute pericarditis
0.774 0.226 0.000
W20-W49 Exposure to inanimate mechanical forces
0.773 0.227 0.000
K86.1 Other chronic pancreatitis
0.771 0.229 0.000
I51.4 Myocarditis, unspecified
0.769 0.231 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.768 0.232 0.000
M06.9 Rheumatoid arthritis, unspecified
0.768 0.232 0.000
M51 Other intervertebral disk disorders
0.767 0.233 0.000
S50-S59 Injuries to the elbow and forearm
0.767 0.233 0.000
D25.1 Intramural leiomyoma of uterus
0.765 0.235 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.761 0.239 0.000
M34 Systemic sclerosis
0.761 0.239 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.761 0.239 0.000
I21 Acute myocardial infarction
0.760 0.240 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.759 0.241 0.000
M50.1 Cervical disk disorder with radiculopathy
0.759 0.241 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.758 0.242 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.757 0.243 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.757 0.243 0.000
M00-M03 Infectious arthropathies
0.757 0.243 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.755 0.245 0.000
K86.8 Other specified diseases of pancreas
0.754 0.246 0.000
C43 Malignant melanoma of skin
0.754 0.246 0.000
E46 Unspecified protein-energy malnutrition
0.754 0.246 0.000
M54.1 Radiculopathy
0.752 0.247 0.000
T42.4 Benzodiazepines
0.752 0.248 0.000
M48.06 Spinal stenosis (Lumbar region)
0.751 0.249 0.000
Y43 Primarily systemic agents
0.751 0.249 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.748 0.252 0.000
E11.6 With other specified complications
0.748 0.252 0.000
C78.2 Secondary malignant neoplasm of pleura
0.747 0.253 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.747 0.253 0.000
T79-T79 Certain early complications of trauma
0.747 0.253 0.000
S01 Open wound of head
0.745 0.255 0.000
O02.1 Missed abortion
0.745 0.255 0.000
S02 Fracture of skull and facial bones
0.744 0.256 0.000
M91-M94 Chondropathies
0.744 0.256 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.743 0.257 0.000
E14 Unspecified diabetes mellitus
0.742 0.258 0.000
I42.0 Dilated cardiomyopathy
0.742 0.258 0.000
I35.8 Other aortic valve disorders
0.741 0.259 0.000
I63.9 Cerebral infarction, unspecified
0.740 0.260 0.000
K81.9 Cholecystitis, unspecified
0.740 0.260 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.739 0.261 0.000
C79.2 Secondary malignant neoplasm of skin
0.739 0.261 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.738 0.262 0.000
O04.4 Incomplete, without complication
0.737 0.263 0.000
D25.2 Subserosal leiomyoma of uterus
0.736 0.264 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.736 0.264 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.735 0.265 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.733 0.267 0.000
M47.2 Other spondylosis with radiculopathy
0.732 0.268 0.000
C78.0 Secondary malignant neoplasm of lung
0.731 0.269 0.000
C34.9 Bronchus or lung, unspecified
0.731 0.269 0.000
T43.2 Other and unspecified antidepressants
0.731 0.269 0.000
S89 Other and unspecified injuries of lower leg
0.731 0.269 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.731 0.269 0.000
M25.77 Osteophyte (Ankle and foot)
0.730 0.270 0.000
I31.9 Disease of pericardium, unspecified
0.730 0.270 0.000
E20-E35 Disorders of other endocrine glands
0.730 0.270 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.729 0.271 0.000
X60-X84 Intentional self-harm
0.727 0.273 0.000
I25 Chronic ischaemic heart disease
0.727 0.273 0.000
M86-M90 Other osteopathies
0.726 0.274 0.000
T86 Failure and rejection of transplanted organs and tissues
0.725 0.275 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.724 0.276 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.724 0.276 0.000
M54.5 Low back pain
0.724 0.276 0.000
K07 Dentofacial anomalies [including malocclusion]
0.722 0.278 0.000
E00-E07 Disorders of thyroid gland
0.722 0.278 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.722 0.278 0.000
I46 Cardiac arrest
0.721 0.279 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.721 0.279 0.000
T78 Adverse effects, not elsewhere classified
0.720 0.280 0.000
I47.0 Reentry ventricular arrhythmia
0.720 0.280 0.000
K81.1 Chronic cholecystitis
0.720 0.280 0.000
Y86 Sequelae of other accidents
0.719 0.281 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.719 0.281 0.000
D25.0 Submucous leiomyoma of uterus
0.719 0.281 0.000
I61 Intracerebral haemorrhage
0.718 0.282 0.000
I11 Hypertensive heart disease
0.718 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I33 Acute and subacute endocarditis
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
E10.9 Without complications
0.716 0.284 0.000
Chapter XXII Codes for special purposes
0.714 0.286 0.000
R20 Disturbances of skin sensation
0.714 0.286 0.000
M24.0 Loose body in joint
0.714 0.286 0.000
D34 Benign neoplasm of thyroid gland
0.714 0.286 0.000
I74 Arterial embolism and thrombosis
0.712 0.288 0.000
R04 Haemorrhage from respiratory passages
0.712 0.288 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.712 0.288 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.712 0.288 0.000
V20-V29 Motorcycle rider injured in transport accident
0.711 0.289 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.711 0.289 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.710 0.290 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.710 0.290 0.000
Y35-Y36 Legal intervention and operations of war
0.710 0.290 0.000
Y10-Y34 Event of undetermined intent
0.710 0.290 0.000
Y00-Y09 Assault
0.710 0.290 0.000
X85-X99 Assault
0.710 0.290 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.710 0.290 0.000
X50-X57 Overexertion, travel and privation
0.710 0.290 0.000
X30-X39 Exposure to forces of nature
0.710 0.290 0.000
X20-X29 Contact with venomous animals and plants
0.710 0.290 0.000
X10-X19 Contact with heat and hot substances
0.710 0.290 0.000
X00-X09 Exposure to smoke, fire and flames
0.710 0.290 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.710 0.290 0.000
W75-W84 Other accidental threats to breathing
0.710 0.290 0.000
W65-W74 Accidental drowning and submersion
0.710 0.290 0.000
W50-W64 Exposure to animate mechanical forces
0.710 0.290 0.000
V98-V99 Other and unspecified transport accidents
0.710 0.290 0.000
V95-V97 Air and space transport accidents
0.710 0.290 0.000
V90-V94 Water transport accidents
0.710 0.290 0.000
V80-V89 Other land transport accidents
0.710 0.290 0.000
V70-V79 Bus occupant injured in transport accident
0.710 0.290 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.710 0.290 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.710 0.290 0.000
V40-V49 Car occupant injured in transport accident
0.710 0.290 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.710 0.290 0.000
V01-V09 Pedestrian injured in transport accident
0.710 0.290 0.000
M53 Other dorsopathies, not elsewhere classified
0.709 0.291 0.000
D12.0 Caecum
0.706 0.294 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.706 0.294 0.000
M49 Spondylopathies in diseases classified elsewhere
0.706 0.294 0.000
I72.3 Aneurysm of iliac artery
0.705 0.295 0.000
O85-O92 Complications predominantly related to the puerperium
0.705 0.295 0.000
E67 Other hyperalimentation
0.704 0.296 0.000
E68 Sequelae of hyperalimentation
0.704 0.296 0.000
E65 Localised adiposity
0.704 0.296 0.000
D12.5 Sigmoid colon
0.704 0.296 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.704 0.296 0.000
T82.1 Mechanical complication of cardiac electronic device
0.704 0.296 0.000
M16 Coxarthrosis [arthrosis of hip]
0.704 0.296 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.703 0.297 0.000
K12.3 Oral mucositis (ulcerative)
0.703 0.297 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.703 0.297 0.000
M54.39 Sciatica (Site unspecified)
0.702 0.298 0.000
D37.0 Lip, oral cavity and pharynx
0.702 0.298 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.701 0.299 0.000
D00-D09 In situ neoplasms
0.700 0.300 0.000
I60 Subarachnoid haemorrhage
0.699 0.300 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.699 0.301 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.699 0.301 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.699 0.301 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.699 0.301 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.698 0.302 0.000
O02.0 Blighted ovum and nonhydatidiform mole
0.697 0.303 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.696 0.304 0.000
E13 Other specified diabetes mellitus
0.696 0.304 0.000
E12 Malnutrition-related diabetes mellitus
0.696 0.304 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.696 0.304 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.696 0.304 0.000
E66.1 Drug-induced obesity
0.696 0.304 0.000
E66.0 Obesity due to excess calories
0.696 0.304 0.000
I25.2 Old myocardial infarction
0.696 0.304 0.000
K86.9 Disease of pancreas, unspecified
0.695 0.305 0.000
S60-S69 Injuries to the wrist and hand
0.695 0.305 0.000
M17 Gonarthrosis [arthrosis of knee]
0.695 0.305 0.000
Q60-Q64 Congenital malformations of the urinary system
0.693 0.307 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.693 0.307 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.693 0.307 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.693 0.307 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.693 0.307 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.693 0.307 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.693 0.307 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.693 0.307 0.000
T36 Poisoning by systemic antibiotics
0.693 0.307 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.691 0.308 0.000
I63.8 Other cerebral infarction
0.691 0.309 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.691 0.309 0.000
Y43.3 Other antineoplastic drugs
0.691 0.309 0.000
I51.6 Cardiovascular disease, unspecified
0.691 0.309 0.000
I51.5 Myocardial degeneration
0.691 0.309 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.691 0.309 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.691 0.309 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.691 0.309 0.000
I51.0 Cardiac septal defect, acquired
0.691 0.309 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.691 0.309 0.000
O07 Failed attempted abortion
0.691 0.309 0.000
O06 Unspecified abortion
0.691 0.309 0.000
O05 Other abortion
0.691 0.309 0.000
O01 Hydatidiform mole
0.691 0.309 0.000
I15 Secondary hypertension
0.691 0.309 0.000
I13 Hypertensive heart and renal disease
0.691 0.309 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.691 0.309 0.000
M79.8 Other specified soft tissue disorders
0.691 0.309 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.690 0.310 0.000
K86.3 Pseudocyst of pancreas
0.690 0.310 0.000
K08 Other disorders of teeth and supporting structures
0.690 0.310 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.690 0.310 0.000
T87 Complications peculiar to reattachment and amputation
0.689 0.311 0.000
S90-S99 Injuries to the ankle and foot
0.689 0.311 0.000
C34.1 Upper lobe, bronchus or lung
0.689 0.311 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.689 0.311 0.000
S70-S79 Injuries to the hip and thigh
0.688 0.312 0.000
K50.0 Crohn's disease of small intestine
0.688 0.312 0.000
I78 Diseases of capillaries
0.688 0.312 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.688 0.312 0.000
S86 Injury of muscle and tendon at lower leg level
0.688 0.312 0.000
K14 Diseases of tongue
0.687 0.313 0.000
K10 Other diseases of jaws
0.687 0.313 0.000
I62 Other nontraumatic intracranial haemorrhage
0.686 0.314 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.685 0.315 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.685 0.315 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.684 0.316 0.000
R04.2 Haemoptysis
0.683 0.317 0.000
O03.9 Complete or unspecified, without complication
0.683 0.317 0.000
I20.8 Other forms of angina pectoris
0.683 0.317 0.000
Chapter V Mental and behavioural disorders
0.683 0.317 0.000
C32 Malignant neoplasm of larynx
0.683 0.317 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.682 0.318 0.000
D12.4 Descending colon
0.681 0.319 0.000
I35.9 Aortic valve disorder, unspecified
0.681 0.319 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.680 0.319 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.680 0.320 0.000
C79.6 Secondary malignant neoplasm of ovary
0.680 0.320 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.680 0.320 0.000
M54.6 Pain in thoracic spine
0.680 0.320 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.679 0.321 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.678 0.322 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.678 0.322 0.000
M54.36 Sciatica (Lumbar region)
0.678 0.322 0.000
M48.02 Spinal stenosis (Cervical region)
0.677 0.323 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.676 0.323 0.000
M54.4 Lumbago with sciatica
0.676 0.324 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.676 0.324 0.000
K70-K77 Diseases of liver
0.676 0.324 0.000
I42.8 Other cardiomyopathies
0.676 0.324 0.000
K81.8 Other cholecystitis
0.676 0.324 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.676 0.324 0.000
I23 Certain current complications following acute myocardial infarction
0.675 0.324 0.000
D36 Benign neoplasm of other and unspecified sites
0.675 0.324 0.000
M48.09 Spinal stenosis (Site unspecified)
0.675 0.325 0.000
L50 Urticaria
0.674 0.325 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.674 0.326 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.673 0.327 0.000
O43 Placental disorders
0.673 0.327 0.000
S05 Injury of eye and orbit
0.672 0.328 0.000
T92 Sequelae of injuries of upper limb
0.671 0.328 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.671 0.329 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.671 0.329 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.671 0.329 0.000
Y98 Lifestyle-related condition
0.671 0.329 0.000
Y97 Environmental-pollution-related condition
0.671 0.329 0.000
Y96 Work-related condition
0.671 0.329 0.000
I07 Rheumatic tricuspid valve diseases
0.671 0.329 0.000
O00 Ectopic pregnancy
0.671 0.329 0.000
D37.2 Small intestine
0.671 0.329 0.000
M80-M85 Disorders of bone density and structure
0.671 0.329 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.671 0.329 0.000
M21 Other acquired deformities of limbs
0.670 0.330 0.000
E50-E64 Other nutritional deficiencies
0.670 0.330 0.000
M45 Ankylosing spondylitis
0.669 0.331 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.668 0.331 0.000
M33 Dermatopolymyositis
0.668 0.331 0.000
M32 Systemic lupus erythematosus
0.668 0.331 0.000
M30 Polyarteritis nodosa and related conditions
0.668 0.331 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.668 0.332 0.000
M48.9 Spondylopathy, unspecified
0.668 0.332 0.000
M48.8 Other specified spondylopathies
0.668 0.332 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.668 0.332 0.000
M48.4 Fatigue fracture of vertebra
0.668 0.332 0.000
M48.3 Traumatic spondylopathy
0.668 0.332 0.000
M48.2 Kissing spine
0.668 0.332 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.668 0.332 0.000
I21.4 Acute subendocardial myocardial infarction
0.667 0.333 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.667 0.333 0.000
I28 Other diseases of pulmonary vessels
0.666 0.334 0.000
I27 Other pulmonary heart diseases
0.666 0.334 0.000
I77.8 Other specified disorders of arteries and arterioles
0.665 0.334 0.000
I77.5 Necrosis of artery
0.665 0.334 0.000
I77.4 Coeliac artery compression syndrome
0.665 0.334 0.000
I77.3 Arterial fibromuscular dysplasia
0.665 0.334 0.000
I77.2 Rupture of artery
0.665 0.334 0.000
I77.0 Arteriovenous fistula, acquired
0.665 0.334 0.000
M54.8 Other dorsalgia
0.665 0.335 0.000
M54.0 Panniculitis affecting regions of neck and back
0.665 0.335 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.665 0.335 0.000
E11.8 With unspecified complications
0.665 0.335 0.000
E11.7 With multiple complications
0.665 0.335 0.000
E11.1 With ketoacidosis
0.665 0.335 0.000
E11.0 With coma
0.665 0.335 0.000
S80.0 Contusion of knee
0.665 0.335 0.000
K85.9 Acute pancreatitis, unspecified
0.664 0.336 0.000
E11.5 With peripheral circulatory complications
0.664 0.336 0.000
L85 Other epidermal thickening
0.664 0.336 0.000
I69.3 Sequelae of cerebral infarction
0.663 0.337 0.000
L10-L14 Bullous disorders
0.663 0.337 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.663 0.337 0.000
I22 Subsequent myocardial infarction
0.662 0.338 0.000
M40-M43 Deforming dorsopathies
0.662 0.338 0.000
E10.1 With ketoacidosis
0.662 0.338 0.000
M22 Disorders of patella
0.661 0.339 0.000
S20 Superficial injury of thorax
0.661 0.339 0.000
I31.8 Other specified diseases of pericardium
0.660 0.340 0.000
I31.2 Haemopericardium, not elsewhere classified
0.660 0.340 0.000
I31.1 Chronic constrictive pericarditis
0.660 0.340 0.000
I31.0 Chronic adhesive pericarditis
0.660 0.340 0.000
C43.7 Malignant melanoma of lower limb, including hip
0.660 0.340 0.000
I47.1 Supraventricular tachycardia
0.658 0.342 0.000
L08 Other local infections of skin and subcutaneous tissue
0.657 0.343 0.000
S80.9 Superficial injury of lower leg, unspecified
0.656 0.344 0.000
E70-E90 Metabolic disorders
0.656 0.344 0.000
M06.0 Seronegative rheumatoid arthritis
0.656 0.344 0.000
D26 Other benign neoplasms of uterus
0.655 0.345 0.000
W22 Striking against or struck by other objects
0.653 0.347 0.000
T93.2 Sequelae of other fractures of lower limb
0.652 0.348 0.000
K82.1 Hydrops of gallbladder
0.652 0.348 0.000
I44 Atrioventricular and left bundle-branch block
0.651 0.349 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.651 0.349 0.000
I72.8 Aneurysm of other specified arteries
0.650 0.349 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.650 0.350 0.000
L91 Hypertrophic disorders of skin
0.650 0.350 0.000
D37.5 Rectum
0.650 0.350 0.000
M47.1 Other spondylosis with myelopathy
0.649 0.351 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.649 0.351 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.649 0.351 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.649 0.351 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.649 0.351 0.000
T82.3 Mechanical complication of other vascular grafts
0.649 0.351 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.649 0.351 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.649 0.351 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.649 0.351 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.649 0.351 0.000
M31 Other necrotising vasculopathies
0.648 0.352 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.647 0.353 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.647 0.353 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.647 0.353 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.647 0.353 0.000
K86.2 Cyst of pancreas
0.647 0.353 0.000
K86.0 Alcohol-induced chronic pancreatitis
0.647 0.353 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.646 0.354 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.646 0.354 0.000
C31 Malignant neoplasm of accessory sinuses
0.646 0.354 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.646 0.354 0.000
C37 Malignant neoplasm of thymus
0.646 0.354 0.000
C33 Malignant neoplasm of trachea
0.646 0.354 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.646 0.354 0.000
O04.8 Complete or unspecified, with other and unspecified complications
0.646 0.354 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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