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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7569074
log Bayes Factor = 12.5456
Chromosome 2   position 33,580,954  (GRCh37) Explore rs7569074 on Ensembl!
Variant rs7569074 is part of Cluster X0191

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
G40-G47 Episodic and paroxysmal disorders
1.000 0.000 0.000
G47 Sleep disorders
1.000 0.000 0.000
G47.3 Sleep apnoea
0.997 0.003 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.997 0.003 0.000
Chapter IX Diseases of the circulatory system
0.996 0.004 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.991 0.009 0.000
M05-M14 Inflammatory polyarthropathies
0.989 0.011 0.000
Chapter XX External causes of morbidity and mortality
0.984 0.016 0.000
G47.9 Sleep disorder, unspecified
0.983 0.017 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.980 0.020 0.000
M06 Other rheumatoid arthritis
0.976 0.024 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.974 0.026 0.000
M06.9 Rheumatoid arthritis, unspecified
0.965 0.035 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.965 0.035 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.964 0.036 0.000
I20-I25 Ischaemic heart diseases
0.960 0.040 0.000
S80-S89 Injuries to the knee and lower leg
0.958 0.042 0.000
M80-M85 Disorders of bone density and structure
0.955 0.045 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.947 0.053 0.000
T93 Sequelae of injuries of lower limb
0.937 0.063 0.000
S20-S29 Injuries to the thorax
0.930 0.070 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.923 0.077 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.923 0.077 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.917 0.083 0.000
Y95 Nosocomial condition
0.915 0.085 0.000
N18.9 Chronic renal failure, unspecified
0.913 0.087 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.911 0.089 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.910 0.090 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.910 0.090 0.000
N18 Chronic renal failure
0.907 0.093 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.901 0.099 0.000
M81 Osteoporosis without pathological fracture
0.900 0.100 0.000
R04 Haemorrhage from respiratory passages
0.899 0.101 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.894 0.106 0.000
R04.0 Epistaxis
0.894 0.106 0.000
I22 Subsequent myocardial infarction
0.893 0.107 0.000
N17-N19 Renal failure
0.891 0.109 0.000
S81 Open wound of lower leg
0.885 0.115 0.000
S90-S99 Injuries to the ankle and foot
0.885 0.115 0.000
R87 Abnormal findings in specimens from female genital organs
0.884 0.116 0.000
Chapter XIV Diseases of the genitourinary system
0.883 0.117 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.882 0.118 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.878 0.122 0.000
R20 Disturbances of skin sensation
0.877 0.123 0.000
I05-I09 Chronic rheumatic heart diseases
0.875 0.125 0.000
G40 Epilepsy
0.873 0.127 0.000
T90 Sequelae of injuries of head
0.872 0.128 0.000
I95 Hypotension
0.872 0.128 0.000
G90-G99 Other disorders of the nervous system
0.870 0.130 0.000
I10-I15 Hypertensive diseases
0.868 0.132 0.000
M81.9 Osteoporosis, unspecified
0.863 0.137 0.000
R87.6 Abnormal cytological findings
0.861 0.139 0.000
T92 Sequelae of injuries of upper limb
0.860 0.140 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.860 0.140 0.000
S70-S79 Injuries to the hip and thigh
0.858 0.142 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.857 0.143 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.857 0.143 0.000
T79-T79 Certain early complications of trauma
0.853 0.146 0.000
R06 Abnormalities of breathing
0.853 0.147 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.852 0.148 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.852 0.148 0.000
Chapter I Certain infectious and parasitic diseases
0.851 0.149 0.000
S50-S59 Injuries to the elbow and forearm
0.851 0.149 0.000
Y86 Sequelae of other accidents
0.848 0.152 0.000
S20 Superficial injury of thorax
0.845 0.155 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.843 0.157 0.000
N18.4 Chronic kidney disease, stage 4
0.842 0.158 0.000
I95.1 Orthostatic hypotension
0.838 0.162 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.831 0.169 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.827 0.173 0.000
M84 Disorders of continuity of bone
0.826 0.174 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.826 0.174 0.000
O30 Multiple gestation
0.824 0.176 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.823 0.177 0.000
Chapter VIII Diseases of the ear and mastoid process
0.823 0.177 0.000
M05 Seropositive rheumatoid arthritis
0.820 0.179 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.820 0.180 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.820 0.180 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.818 0.182 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.813 0.186 0.000
S81.0 Open wound of knee
0.813 0.187 0.000
M91-M94 Chondropathies
0.812 0.187 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.811 0.189 0.000
I12 Hypertensive renal disease
0.809 0.191 0.000
R20.2 Paraesthesia of skin
0.809 0.191 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.809 0.191 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.807 0.193 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.805 0.195 0.000
I20 Angina pectoris
0.805 0.195 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.805 0.195 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.804 0.196 0.000
I21 Acute myocardial infarction
0.801 0.199 0.000
I25 Chronic ischaemic heart disease
0.798 0.202 0.000
T98 Sequelae of other and unspecified effects of external causes
0.795 0.205 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.793 0.207 0.000
M07 Psoriatic and enteropathic arthropathies
0.793 0.207 0.000
S89 Other and unspecified injuries of lower leg
0.790 0.210 0.000
R06.2 Wheezing
0.790 0.210 0.000
O47 False labour
0.790 0.210 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.790 0.210 0.000
O42 Premature rupture of membranes
0.790 0.210 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.789 0.211 0.000
X60-X84 Intentional self-harm
0.788 0.212 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.785 0.215 0.000
M60-M63 Disorders of muscles
0.784 0.216 0.000
W20-W49 Exposure to inanimate mechanical forces
0.784 0.216 0.000
M70-M79 Other soft tissue disorders
0.784 0.216 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.782 0.218 0.000
T39.0 Salicylates
0.782 0.218 0.000
R26 Abnormalities of gait and mobility
0.782 0.218 0.000
N60-N64 Disorders of breast
0.782 0.218 0.000
Chapter XXII Codes for special purposes
0.780 0.220 0.000
A30-A49 Other bacterial diseases
0.780 0.220 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.779 0.221 0.000
I05 Rheumatic mitral valve diseases
0.778 0.222 0.000
T93.1 Sequelae of fracture of femur
0.775 0.225 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.772 0.228 0.000
I97.1 Other functional disturbances following cardiac surgery
0.771 0.229 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.770 0.230 0.000
M40-M43 Deforming dorsopathies
0.769 0.231 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.768 0.232 0.000
M14 Arthropathies in other diseases classified elsewhere
0.766 0.234 0.000
I99 Other and unspecified disorders of circulatory system
0.766 0.234 0.000
I73 Other peripheral vascular diseases
0.766 0.234 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.765 0.235 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.764 0.236 0.000
S10-S19 Injuries to the neck
0.764 0.236 0.000
N62 Hypertrophy of breast
0.763 0.237 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.762 0.238 0.000
Chapter VII Diseases of the eye and adnexa
0.762 0.238 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.761 0.239 0.000
I60-I69 Cerebrovascular diseases
0.761 0.239 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.760 0.240 0.000
T91 Sequelae of injuries of neck and trunk
0.760 0.240 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.760 0.240 0.000
M06.3 Rheumatoid nodule
0.756 0.244 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.756 0.244 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.755 0.245 0.000
S27 Injury of other and unspecified intrathoracic organs
0.754 0.246 0.000
S40-S49 Injuries to the shoulder and upper arm
0.753 0.247 0.000
O30.0 Twin pregnancy
0.753 0.247 0.000
T93.2 Sequelae of other fractures of lower limb
0.751 0.249 0.000
V40-V49 Car occupant injured in transport accident
0.750 0.250 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.749 0.250 0.000
O42.9 Premature rupture of membranes, unspecified
0.749 0.251 0.000
O80-O84 Delivery
0.749 0.251 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.749 0.251 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.746 0.254 0.000
R21 Rash and other nonspecific skin eruption
0.746 0.254 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.746 0.254 0.000
S72 Fracture of femur
0.745 0.255 0.000
T40.2 Other opioids
0.744 0.256 0.000
N00-N08 Glomerular diseases
0.743 0.257 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.743 0.257 0.000
S51 Open wound of forearm
0.743 0.257 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.742 0.258 0.000
M65-M68 Disorders of synovium and tendon
0.740 0.260 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.740 0.260 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.740 0.260 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.738 0.262 0.000
H90-H95 Other disorders of ear
0.738 0.262 0.000
M13 Other arthritis
0.736 0.264 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.735 0.265 0.000
O40 Polyhydramnios
0.735 0.265 0.000
G70-G73 Diseases of myoneural junction and muscle
0.734 0.266 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.733 0.267 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.733 0.267 0.000
I70 Atherosclerosis
0.732 0.268 0.000
G30-G32 Other degenerative diseases of the nervous system
0.732 0.268 0.000
M86-M90 Other osteopathies
0.731 0.269 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.731 0.269 0.000
O24 Diabetes mellitus in pregnancy
0.731 0.269 0.000
R06.0 Dyspnoea
0.728 0.272 0.000
S80 Superficial injury of lower leg
0.727 0.273 0.000
I20.8 Other forms of angina pectoris
0.727 0.273 0.000
S20.8 Superficial injuries of other and unspecified parts of thorax
0.726 0.274 0.000
Y40 Systemic antibiotics
0.725 0.275 0.000
H60-H62 Diseases of external ear
0.725 0.275 0.000
R06.5 Mouth breathing
0.725 0.275 0.000
S20.2 Contusion of thorax
0.724 0.276 0.000
I08 Multiple valve diseases
0.724 0.276 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.723 0.277 0.000
O85-O92 Complications predominantly related to the puerperium
0.723 0.277 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.723 0.277 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.722 0.278 0.000
R23 Other skin changes
0.721 0.279 0.000
O00-O08 Pregnancy with abortive outcome
0.720 0.280 0.000
B07 Viral warts
0.720 0.280 0.000
I12.9 Hypertensive renal disease without renal failure
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.717 0.283 0.000
G47.8 Other sleep disorders
0.717 0.283 0.000
G47.4 Narcolepsy and cataplexy
0.717 0.283 0.000
G47.2 Disorders of the sleep-wake schedule
0.717 0.283 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.715 0.285 0.000
O43 Placental disorders
0.714 0.285 0.000
I00-I02 Acute rheumatic fever
0.714 0.286 0.000
I73.0 Raynaud's syndrome
0.713 0.287 0.000
G41 Status epilepticus
0.712 0.288 0.000
H55-H59 Other disorders of eye and adnexa
0.712 0.288 0.000
S86 Injury of muscle and tendon at lower leg level
0.712 0.288 0.000
Q60-Q64 Congenital malformations of the urinary system
0.712 0.288 0.000
T95 Sequelae of burns, corrosions and frostbite
0.711 0.289 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.711 0.289 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.711 0.289 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.711 0.289 0.000
G90 Disorders of autonomic nervous system
0.711 0.289 0.000
H91 Other hearing loss
0.710 0.290 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.709 0.291 0.000
M12 Other specific arthropathies
0.709 0.291 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.709 0.291 0.000
M08 Juvenile arthritis
0.709 0.291 0.000
T39.1 4-Aminophenol derivatives
0.709 0.291 0.000
T92.0 Sequelae of open wound of upper limb
0.709 0.291 0.000
Y52 Agents primarily affecting the cardiovascular system
0.708 0.292 0.000
I72 Other aneurysm
0.707 0.293 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.706 0.294 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.706 0.294 0.000
Y35-Y36 Legal intervention and operations of war
0.706 0.294 0.000
Y10-Y34 Event of undetermined intent
0.706 0.294 0.000
Y00-Y09 Assault
0.706 0.294 0.000
X85-X99 Assault
0.706 0.294 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.706 0.294 0.000
X50-X57 Overexertion, travel and privation
0.706 0.294 0.000
X30-X39 Exposure to forces of nature
0.706 0.294 0.000
X20-X29 Contact with venomous animals and plants
0.706 0.294 0.000
X10-X19 Contact with heat and hot substances
0.706 0.294 0.000
X00-X09 Exposure to smoke, fire and flames
0.706 0.294 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.706 0.294 0.000
W75-W84 Other accidental threats to breathing
0.706 0.294 0.000
W65-W74 Accidental drowning and submersion
0.706 0.294 0.000
W50-W64 Exposure to animate mechanical forces
0.706 0.294 0.000
V98-V99 Other and unspecified transport accidents
0.706 0.294 0.000
V95-V97 Air and space transport accidents
0.706 0.294 0.000
V90-V94 Water transport accidents
0.706 0.294 0.000
V70-V79 Bus occupant injured in transport accident
0.706 0.294 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.706 0.294 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.706 0.294 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.706 0.294 0.000
V01-V09 Pedestrian injured in transport accident
0.706 0.294 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.706 0.294 0.000
Chapter XXI Factors influencing health status and contact with health services
0.705 0.295 0.000
I15 Secondary hypertension
0.705 0.295 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.705 0.295 0.000
I12.0 Hypertensive renal disease with renal failure
0.704 0.296 0.000
I11 Hypertensive heart disease
0.703 0.297 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.703 0.297 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.702 0.298 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.702 0.298 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.702 0.298 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.702 0.298 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.702 0.298 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.702 0.298 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.702 0.298 0.000
T36 Poisoning by systemic antibiotics
0.702 0.298 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.702 0.298 0.000
Y57 Other and unspecified drugs and medicaments
0.702 0.298 0.000
T14 Injury of unspecified body region
0.701 0.299 0.000
G20-G26 Extrapyramidal and movement disorders
0.700 0.300 0.000
M11 Other crystal arthropathies
0.700 0.300 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.700 0.300 0.000
T92.9 Sequelae of unspecified injury of upper limb
0.700 0.300 0.000
M06.8 Other specified rheumatoid arthritis
0.700 0.300 0.000
M06.4 Inflammatory polyarthropathy
0.700 0.300 0.000
M06.2 Rheumatoid bursitis
0.700 0.300 0.000
M06.1 Adult-onset Still's disease
0.700 0.300 0.000
M84.0 Malunion of fracture
0.699 0.301 0.000
I21.9 Acute myocardial infarction, unspecified
0.698 0.302 0.000
S99 Other and unspecified injuries of ankle and foot
0.698 0.302 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.696 0.304 0.000
V20-V29 Motorcycle rider injured in transport accident
0.696 0.304 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.696 0.304 0.000
O26.9 Pregnancy-related condition, unspecified
0.695 0.304 0.000
G93 Other disorders of brain
0.694 0.306 0.000
R09.3 Abnormal sputum
0.693 0.307 0.000
G44 Other headache syndromes
0.693 0.307 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.692 0.308 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.692 0.308 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.692 0.308 0.000
S91 Open wound of ankle and foot
0.691 0.309 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.691 0.309 0.000
N64 Other disorders of breast
0.690 0.310 0.000
H91.9 Hearing loss, unspecified
0.690 0.310 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.690 0.310 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.689 0.311 0.000
I23 Certain current complications following acute myocardial infarction
0.688 0.312 0.000
R01 Cardiac murmurs and other cardiac sounds
0.688 0.312 0.000
S81.8 Open wound of other parts of lower leg
0.688 0.312 0.000
S88 Traumatic amputation of lower leg
0.687 0.313 0.000
S87 Crushing injury of lower leg
0.687 0.313 0.000
S85 Injury of blood vessels at lower leg level
0.687 0.313 0.000
S84 Injury of nerves at lower leg level
0.687 0.313 0.000
R27 Other lack of coordination
0.687 0.313 0.000
M85 Other disorders of bone density and structure
0.686 0.314 0.000
M83 Adult osteomalacia
0.685 0.315 0.000
M82 Osteoporosis in diseases classified elsewhere
0.685 0.315 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.684 0.316 0.000
A80-A89 Viral infections of the central nervous system
0.683 0.317 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.683 0.317 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.682 0.318 0.000
O44 Placenta praevia
0.681 0.319 0.000
T31 Burns classified according to extent of body surface involved
0.680 0.320 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.679 0.321 0.000
Y98 Lifestyle-related condition
0.679 0.321 0.000
Y97 Environmental-pollution-related condition
0.679 0.321 0.000
Y96 Work-related condition
0.679 0.321 0.000
V80-V89 Other land transport accidents
0.679 0.321 0.000
S90 Superficial injury of ankle and foot
0.678 0.322 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.678 0.322 0.000
Q50-Q56 Congenital malformations of genital organs
0.678 0.322 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.678 0.322 0.000
I05.9 Mitral valve disease, unspecified
0.677 0.323 0.000
I20.1 Angina pectoris with documented spasm
0.677 0.323 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.676 0.324 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.676 0.324 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.673 0.327 0.000
I25.5 Ischaemic cardiomyopathy
0.672 0.328 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.671 0.328 0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb
0.671 0.328 0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb
0.671 0.328 0.000
T93.4 Sequelae of injury of nerve of lower limb
0.671 0.328 0.000
T93.0 Sequelae of open wound of lower limb
0.671 0.328 0.000
B00 Herpesviral [herpes simplex] infections
0.671 0.329 0.000
H55 Nystagmus and other irregular eye movements
0.671 0.329 0.000
S72.3 Fracture of shaft of femur
0.671 0.329 0.000
M06.0 Seronegative rheumatoid arthritis
0.671 0.329 0.000
N18.3 Chronic kidney disease, stage 3
0.670 0.330 0.000
S89.9 Unspecified injury of lower leg
0.670 0.330 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.669 0.330 0.000
A49 Bacterial infection of unspecified site
0.669 0.331 0.000
G12 Spinal muscular atrophy and related syndromes
0.669 0.331 0.000
O47.0 False labour before 37 completed weeks of gestation
0.667 0.333 0.000
S29 Other and unspecified injuries of thorax
0.667 0.333 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.667 0.333 0.000
S26 Injury of heart
0.667 0.333 0.000
S25 Injury of blood vessels of thorax
0.667 0.333 0.000
S24 Injury of nerves and spinal cord at thorax level
0.667 0.333 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.667 0.333 0.000
S21 Open wound of thorax
0.667 0.333 0.000
T90.9 Sequelae of unspecified injury of head
0.666 0.334 0.000
Q80-Q89 Other congenital malformations
0.665 0.335 0.000
Q21 Congenital malformations of cardiac septa
0.665 0.335 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.664 0.336 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.664 0.336 0.000
N17 Acute renal failure
0.664 0.336 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.663 0.337 0.000
R09.2 Respiratory arrest
0.662 0.338 0.000
O45 Premature separation of placenta [abruptio placentae]
0.662 0.338 0.000
O33 Maternal care for known or suspected disproportion
0.662 0.338 0.000
O31 Complications specific to multiple gestation
0.662 0.338 0.000
T23 Burn and corrosion of wrist and hand
0.661 0.339 0.000
S51.0 Open wound of elbow
0.661 0.339 0.000
S82 Fracture of lower leg, including ankle
0.661 0.339 0.000
G40.8 Other epilepsy
0.659 0.341 0.000
L91 Hypertrophic disorders of skin
0.658 0.342 0.000
O41 Other disorders of amniotic fluid and membranes
0.658 0.342 0.000
R89 Abnormal findings in specimens from other organs, systems and tissues
0.658 0.342 0.000
R86 Abnormal findings in specimens from male genital organs
0.658 0.342 0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity
0.658 0.342 0.000
R84 Abnormal findings in specimens from respiratory organs and thorax
0.658 0.342 0.000
R83 Abnormal findings in cerebrospinal fluid
0.658 0.342 0.000
G96 Other disorders of central nervous system
0.657 0.343 0.000
H61 Other disorders of external ear
0.657 0.343 0.000
Q00-Q07 Congenital malformations of the nervous system
0.655 0.345 0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified
0.655 0.345 0.000
Chapter V Mental and behavioural disorders
0.655 0.345 0.000
I95.2 Hypotension due to drugs
0.655 0.345 0.000
Z22 Carrier of infectious disease
0.654 0.346 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.653 0.347 0.000
M07.3 Other psoriatic arthropathies
0.653 0.347 0.000
T87 Complications peculiar to reattachment and amputation
0.653 0.347 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.653 0.347 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.652 0.347 0.000
Q35-Q37 Cleft lip and cleft palate
0.652 0.347 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.652 0.347 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.652 0.347 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.652 0.348 0.000
S81.9 Open wound of lower leg, part unspecified
0.651 0.348 0.000
N18.8 Other chronic renal failure
0.650 0.349 0.000
N18.1 Chronic kidney disease, stage 1
0.650 0.349 0.000
W22 Striking against or struck by other objects
0.649 0.351 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.649 0.351 0.000
T40.4 Other synthetic narcotics
0.648 0.352 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.647 0.353 0.000
L40-L45 Papulosquamous disorders
0.647 0.353 0.000
M92 Other juvenile osteochondrosis
0.646 0.353 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.646 0.354 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.646 0.354 0.000
T39.4 Antirheumatics, not elsewhere classified
0.646 0.354 0.000
T39.2 Pyrazolone derivatives
0.646 0.354 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.646 0.354 0.000
M80 Osteoporosis with pathological fracture
0.645 0.354 0.000
N18.5 Chronic kidney disease, stage 5
0.645 0.354 0.000
M81.8 Other osteoporosis
0.645 0.355 0.000
M81.6 Localised osteoporosis [Lequesne]
0.645 0.355 0.000
M81.5 Idiopathic osteoporosis
0.645 0.355 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.645 0.355 0.000
M81.2 Osteoporosis of disuse
0.645 0.355 0.000
M81.1 Postoophorectomy osteoporosis
0.645 0.355 0.000
M81.0 Postmenopausal osteoporosis
0.645 0.355 0.000
R04.9 Haemorrhage from respiratory passages, unspecified
0.645 0.355 0.000
R04.8 Haemorrhage from other sites in respiratory passages
0.645 0.355 0.000
R04.1 Haemorrhage from throat
0.645 0.355 0.000
O20 Haemorrhage in early pregnancy
0.644 0.356 0.000
M84.4 Pathological fracture, not elsewhere classified
0.644 0.356 0.000
O16 Unspecified maternal hypertension
0.643 0.357 0.000
S92 Fracture of foot, except ankle
0.642 0.358 0.000
M20-M25 Other joint disorders
0.642 0.358 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.642 0.358 0.000
S00-S09 Injuries to the head
0.641 0.359 0.000
Y89 Sequelae of other external causes
0.641 0.359 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.641 0.359 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.641 0.359 0.000
N18.0 End-stage renal disease
0.640 0.359 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.640 0.360 0.000
I22.8 Subsequent myocardial infarction of other sites
0.640 0.360 0.000
T79.7 Traumatic subcutaneous emphysema
0.638 0.361 0.000
N03 Chronic nephritic syndrome
0.638 0.361 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.638 0.362 0.000
R09.1 Pleurisy
0.637 0.363 0.000
S60-S69 Injuries to the wrist and hand
0.636 0.364 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.636 0.364 0.000
A48 Other bacterial diseases, not elsewhere classified
0.635 0.365 0.000
S81.7 Multiple open wounds of lower leg
0.634 0.365 0.000
S98 Traumatic amputation of ankle and foot
0.634 0.366 0.000
S97 Crushing injury of ankle and foot
0.634 0.366 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.634 0.366 0.000
S95 Injury of blood vessels at ankle and foot level
0.634 0.366 0.000
S94 Injury of nerves at ankle and foot level
0.634 0.366 0.000
R87.9 Unspecified abnormal finding
0.634 0.366 0.000
R87.8 Other abnormal findings
0.634 0.366 0.000
R87.7 Abnormal histological findings
0.634 0.366 0.000
R87.5 Abnormal microbiological findings
0.634 0.366 0.000
R87.4 Abnormal immunological findings
0.634 0.366 0.000
R87.3 Abnormal level of substances chiefly nonmedicinal as to source
0.634 0.366 0.000
R87.2 Abnormal level of other drugs, medicaments and biological substances
0.634 0.366 0.000
R87.1 Abnormal level of hormones
0.634 0.366 0.000
R87.0 Abnormal level of enzymes
0.634 0.366 0.000
R02 Gangrene, not elsewhere classified
0.633 0.367 0.000
R05 Cough
0.633 0.367 0.000
O29 Complications of anaesthesia during pregnancy
0.633 0.367 0.000
O28 Abnormal findings on antenatal screening of mother
0.633 0.367 0.000
O23 Infections of genito-urinary tract in pregnancy
0.633 0.367 0.000
O22 Venous complications in pregnancy
0.633 0.367 0.000
O25 Malnutrition in pregnancy
0.633 0.367 0.000
R43 Disturbances of smell and taste
0.632 0.368 0.000
T42.4 Benzodiazepines
0.632 0.368 0.000
M41 Scoliosis
0.632 0.368 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.632 0.368 0.000
S70 Superficial injury of hip and thigh
0.632 0.368 0.000
M62 Other disorders of muscle
0.631 0.369 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.631 0.369 0.000
M94 Other disorders of cartilage
0.631 0.369 0.000
I20.0 Unstable angina
0.630 0.370 0.000
T92.1 Sequelae of fracture of arm
0.630 0.370 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.629 0.371 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.629 0.371 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.629 0.371 0.000
T42.3 Barbiturates
0.629 0.371 0.000
T42.2 Succinimides and oxazolidinediones
0.629 0.371 0.000
T42.1 Iminostilbenes
0.629 0.371 0.000
T42.0 Hydantoin derivatives
0.629 0.371 0.000
R20.3 Hyperaesthesia
0.628 0.371 0.000
R20.1 Hypoaesthesia of skin
0.628 0.371 0.000
R20.0 Anaesthesia of skin
0.628 0.371 0.000
N18.2 Chronic kidney disease, stage 2
0.628 0.372 0.000
Z22.3 Carrier of other specified bacterial diseases
0.627 0.373 0.000
I09 Other rheumatic heart diseases
0.627 0.373 0.000
I06 Rheumatic aortic valve diseases
0.627 0.373 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.626 0.374 0.000
G40.5 Special epileptic syndromes
0.626 0.374 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.626 0.374 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.626 0.374 0.000
S79 Other and unspecified injuries of hip and thigh
0.626 0.374 0.000
O80 Single spontaneous delivery
0.626 0.374 0.000
T90.8 Sequelae of other specified injuries of head
0.625 0.374 0.000
T90.5 Sequelae of intracranial injury
0.625 0.374 0.000
T90.4 Sequelae of injury of eye and orbit
0.625 0.374 0.000
T90.3 Sequelae of injury of cranial nerves
0.625 0.374 0.000
T90.1 Sequelae of open wound of head
0.625 0.374 0.000
T90.0 Sequelae of superficial injury of head
0.625 0.374 0.000
I95.8 Other hypotension
0.625 0.375 0.000
I95.0 Idiopathic hypotension
0.625 0.375 0.000
R45 Symptoms and signs involving emotional state
0.625 0.375 0.000
I05.2 Mitral stenosis with insufficiency
0.625 0.375 0.000
M81.4 Drug-induced osteoporosis
0.624 0.376 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.623 0.376 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.623 0.376 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.623 0.376 0.000
G92 Toxic encephalopathy
0.623 0.376 0.000
M77 Other enthesopathies
0.623 0.377 0.000
M50-M54 Other dorsopathies
0.623 0.377 0.000
I13 Hypertensive heart and renal disease
0.622 0.378 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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