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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75743047
log Bayes Factor = 9.47116
Chromosome 18   position 33,411,351  (GRCh37) Explore rs75743047 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
0.998 0.002 0.000
Chapter VI Diseases of the nervous system
0.994 0.006 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.991 0.009 0.000
S70-S79 Injuries to the hip and thigh
0.990 0.010 0.000
Chapter XX External causes of morbidity and mortality
0.989 0.011 0.000
B95-B98 Bacterial, viral and other infectious agents
0.985 0.015 0.000
E10-E14 Diabetes mellitus
0.982 0.018 0.000
S72 Fracture of femur
0.982 0.018 0.000
E11 Non-insulin-dependent diabetes mellitus
0.974 0.026 0.000
S80-S89 Injuries to the knee and lower leg
0.973 0.027 0.000
H30-H36 Disorders of choroid and retina
0.972 0.028 0.000
S72.0 Fracture of neck of femur
0.971 0.029 0.000
S72.00 Fracture of neck of femur (closed)
0.963 0.037 0.000
Chapter IX Diseases of the circulatory system
0.958 0.042 0.000
S90-S99 Injuries to the ankle and foot
0.958 0.042 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.952 0.048 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.950 0.050 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.947 0.053 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.946 0.054 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.943 0.057 0.000
H10-H13 Disorders of conjunctiva
0.942 0.058 0.000
E11.3 With ophthalmic complications
0.939 0.061 0.000
S82 Fracture of lower leg, including ankle
0.934 0.066 0.000
E11.4 With neurological complications
0.929 0.071 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.926 0.074 0.000
H35 Other retinal disorders
0.923 0.077 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.913 0.087 0.000
B07 Viral warts
0.908 0.092 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.907 0.093 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.898 0.102 0.000
H04 Disorders of lachrymal system
0.895 0.105 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.892 0.108 0.000
S00-S09 Injuries to the head
0.891 0.109 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.889 0.111 0.000
I20-I25 Ischaemic heart diseases
0.889 0.111 0.000
I05-I09 Chronic rheumatic heart diseases
0.888 0.112 0.000
H35.3 Degeneration of macula and posterior pole
0.886 0.114 0.000
E20-E35 Disorders of other endocrine glands
0.886 0.114 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.884 0.116 0.000
G35 Multiple sclerosis
0.884 0.116 0.000
H36 Retinal disorders in diseases classified elsewhere
0.881 0.119 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.881 0.119 0.000
Chapter V Mental and behavioural disorders
0.878 0.122 0.000
H53-H54 Visual disturbances and blindness
0.877 0.123 0.000
W00-W19 Falls
0.875 0.125 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.871 0.129 0.000
H11 Other disorders of conjunctiva
0.871 0.129 0.000
H52 Disorders of refraction and accommodation
0.870 0.130 0.000
S72.4 Fracture of lower end of femur
0.867 0.133 0.000
G90-G99 Other disorders of the nervous system
0.866 0.134 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.866 0.134 0.000
S91 Open wound of ankle and foot
0.866 0.134 0.000
G63.2 Diabetic polyneuropathy
0.863 0.137 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.852 0.148 0.000
S90 Superficial injury of ankle and foot
0.849 0.151 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.844 0.156 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.844 0.156 0.000
Q60-Q64 Congenital malformations of the urinary system
0.840 0.160 0.000
S60-S69 Injuries to the wrist and hand
0.839 0.161 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.832 0.168 0.000
I20 Angina pectoris
0.830 0.170 0.000
I30-I52 Other forms of heart disease
0.829 0.171 0.000
S71 Open wound of hip and thigh
0.824 0.176 0.000
H04.2 Epiphora
0.823 0.177 0.000
B65-B83 Helminthiases
0.822 0.178 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.822 0.178 0.000
E11.5 With peripheral circulatory complications
0.821 0.179 0.000
G37 Other demyelinating diseases of central nervous system
0.819 0.181 0.000
E11.8 With unspecified complications
0.818 0.182 0.000
H52.2 Astigmatism
0.818 0.182 0.000
H36.0 Diabetic retinopathy
0.817 0.183 0.000
S40-S49 Injuries to the shoulder and upper arm
0.813 0.187 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.811 0.189 0.000
B15-B19 Viral hepatitis
0.810 0.190 0.000
G70-G73 Diseases of myoneural junction and muscle
0.810 0.190 0.000
E10 Insulin-dependent diabetes mellitus
0.809 0.191 0.000
I20.9 Angina pectoris, unspecified
0.809 0.191 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.808 0.192 0.000
S82.2 Fracture of shaft of tibia
0.808 0.192 0.000
S02 Fracture of skull and facial bones
0.805 0.195 0.000
H54 Blindness and low vision
0.804 0.196 0.000
S06 Intracranial injury
0.800 0.200 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.800 0.200 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.797 0.203 0.000
E11.6 With other specified complications
0.796 0.204 0.000
Chapter X Diseases of the respiratory system
0.794 0.206 0.000
Y95 Nosocomial condition
0.794 0.206 0.000
E40-E46 Malnutrition
0.793 0.207 0.000
I08 Multiple valve diseases
0.792 0.208 0.000
S82.4 Fracture of fibula alone
0.792 0.208 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.790 0.210 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.790 0.210 0.000
S82.5 Fracture of medial malleolus
0.789 0.211 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.789 0.211 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.787 0.213 0.000
H10 Conjunctivitis
0.786 0.214 0.000
I50 Heart failure
0.786 0.214 0.000
S72.40 Fracture of lower end of femur (closed)
0.785 0.215 0.000
T92 Sequelae of injuries of upper limb
0.785 0.215 0.000
Chapter VIII Diseases of the ear and mastoid process
0.784 0.216 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.784 0.216 0.000
A80-A89 Viral infections of the central nervous system
0.783 0.217 0.000
G81 Hemiplegia
0.782 0.218 0.000
J84 Other interstitial pulmonary diseases
0.781 0.219 0.000
G30-G32 Other degenerative diseases of the nervous system
0.781 0.219 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.780 0.220 0.000
V40-V49 Car occupant injured in transport accident
0.780 0.220 0.000
M80-M85 Disorders of bone density and structure
0.779 0.221 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.778 0.222 0.000
H35.7 Separation of retinal layers
0.775 0.225 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.774 0.226 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.773 0.227 0.000
Q80-Q89 Other congenital malformations
0.773 0.227 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.773 0.227 0.000
H50 Other strabismus
0.773 0.227 0.000
I05 Rheumatic mitral valve diseases
0.772 0.227 0.000
S90.9 Superficial injury of ankle and foot, unspecified
0.772 0.228 0.000
S91.3 Open wound of other parts of foot
0.771 0.229 0.000
S82.0 Fracture of patella
0.770 0.229 0.000
M81 Osteoporosis without pathological fracture
0.770 0.230 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.770 0.230 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.769 0.231 0.000
S81 Open wound of lower leg
0.767 0.233 0.000
I22 Subsequent myocardial infarction
0.766 0.234 0.000
Q61 Cystic kidney disease
0.766 0.234 0.000
M81.9 Osteoporosis, unspecified
0.764 0.236 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.763 0.237 0.000
H18 Other disorders of cornea
0.762 0.238 0.000
V80-V89 Other land transport accidents
0.762 0.238 0.000
W07 Fall involving chair
0.761 0.239 0.000
S82.3 Fracture of lower end of tibia
0.760 0.240 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.758 0.242 0.000
S50-S59 Injuries to the elbow and forearm
0.758 0.242 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.758 0.242 0.000
E27 Other disorders of adrenal gland
0.758 0.242 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.757 0.243 0.000
H54.9 Unspecified visual impairment (binocular)
0.756 0.244 0.000
I45 Other conduction disorders
0.756 0.244 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.756 0.244 0.000
H11.3 Conjunctival haemorrhage
0.756 0.244 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.755 0.245 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.755 0.245 0.000
W50-W64 Exposure to animate mechanical forces
0.751 0.249 0.000
Chapter XXII Codes for special purposes
0.749 0.250 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.748 0.252 0.000
T00-T07 Injuries involving multiple body regions
0.746 0.254 0.000
A30-A49 Other bacterial diseases
0.745 0.255 0.000
H49 Paralytic strabismus
0.744 0.256 0.000
I50.9 Heart failure, unspecified
0.744 0.256 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.743 0.257 0.000
H31 Other disorders of choroid
0.743 0.257 0.000
S86 Injury of muscle and tendon at lower leg level
0.740 0.260 0.000
H11.9 Disorder of conjunctiva, unspecified
0.740 0.260 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.739 0.261 0.000
H35.0 Background retinopathy and retinal vascular changes
0.736 0.264 0.000
T79-T79 Certain early complications of trauma
0.736 0.264 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.735 0.265 0.000
S10-S19 Injuries to the neck
0.735 0.265 0.000
S72.3 Fracture of shaft of femur
0.734 0.266 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.734 0.266 0.000
H35.9 Retinal disorder, unspecified
0.731 0.269 0.000
V20-V29 Motorcycle rider injured in transport accident
0.728 0.271 0.000
B01 Varicella [chickenpox]
0.727 0.273 0.000
G96 Other disorders of central nervous system
0.726 0.274 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.724 0.276 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.723 0.277 0.000
B99-B99 Other infectious diseases
0.722 0.278 0.000
G81.9 Hemiplegia, unspecified
0.721 0.279 0.000
S82.1 Fracture of upper end of tibia
0.720 0.280 0.000
Y00-Y09 Assault
0.720 0.280 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.719 0.281 0.000
X20-X29 Contact with venomous animals and plants
0.719 0.281 0.000
X50-X57 Overexertion, travel and privation
0.718 0.282 0.000
E24 Cushing's syndrome
0.718 0.282 0.000
S82.20 Fracture of shaft of tibia (closed)
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.715 0.285 0.000
B50-B64 Protozoal diseases
0.715 0.285 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.715 0.285 0.000
A75-A79 Rickettsioses
0.715 0.285 0.000
A70-A74 Other diseases caused by chlamydiae
0.715 0.285 0.000
A65-A69 Other spirochaetal diseases
0.715 0.285 0.000
A20-A28 Certain zoonotic bacterial diseases
0.715 0.285 0.000
A15-A19 Tuberculosis
0.715 0.285 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.715 0.285 0.000
H01 Other inflammation of eyelid
0.715 0.285 0.000
T90 Sequelae of injuries of head
0.711 0.289 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.711 0.289 0.000
E14 Unspecified diabetes mellitus
0.710 0.290 0.000
S78 Traumatic amputation of hip and thigh
0.710 0.290 0.000
S77 Crushing injury of hip and thigh
0.710 0.290 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.710 0.290 0.000
S75 Injury of blood vessels at hip and thigh level
0.710 0.290 0.000
S74 Injury of nerves at hip and thigh level
0.710 0.290 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.710 0.290 0.000
V10-V19 Pedal cyclist injured in transport accident
0.709 0.291 0.000
Y35-Y36 Legal intervention and operations of war
0.709 0.291 0.000
Y10-Y34 Event of undetermined intent
0.709 0.291 0.000
X85-X99 Assault
0.709 0.291 0.000
X30-X39 Exposure to forces of nature
0.709 0.291 0.000
X10-X19 Contact with heat and hot substances
0.709 0.291 0.000
X00-X09 Exposure to smoke, fire and flames
0.709 0.291 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.709 0.291 0.000
W75-W84 Other accidental threats to breathing
0.709 0.291 0.000
W65-W74 Accidental drowning and submersion
0.709 0.291 0.000
V98-V99 Other and unspecified transport accidents
0.709 0.291 0.000
V95-V97 Air and space transport accidents
0.709 0.291 0.000
V90-V94 Water transport accidents
0.709 0.291 0.000
V70-V79 Bus occupant injured in transport accident
0.709 0.291 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.709 0.291 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.709 0.291 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.709 0.291 0.000
V01-V09 Pedestrian injured in transport accident
0.709 0.291 0.000
E65-E68 Obesity and other hyperalimentation
0.709 0.291 0.000
E50-E64 Other nutritional deficiencies
0.708 0.292 0.000
E11.1 With ketoacidosis
0.706 0.293 0.000
S71.1 Open wound of thigh
0.705 0.295 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.704 0.295 0.000
E12 Malnutrition-related diabetes mellitus
0.704 0.296 0.000
S72.9 Fracture of femur, part unspecified
0.704 0.296 0.000
S72.8 Fractures of other parts of femur
0.704 0.296 0.000
S72.7 Multiple fractures of femur
0.704 0.296 0.000
H60-H62 Diseases of external ear
0.702 0.298 0.000
S42 Fracture of shoulder and upper arm
0.701 0.299 0.000
F99-F99 Unspecified mental disorder
0.701 0.299 0.000
F70-F79 Mental retardation
0.701 0.299 0.000
S99 Other and unspecified injuries of ankle and foot
0.700 0.300 0.000
E34 Other endocrine disorders
0.700 0.300 0.000
E11.7 With multiple complications
0.699 0.301 0.000
I46 Cardiac arrest
0.698 0.302 0.000
S88 Traumatic amputation of lower leg
0.697 0.302 0.000
S87 Crushing injury of lower leg
0.697 0.302 0.000
S85 Injury of blood vessels at lower leg level
0.697 0.302 0.000
S84 Injury of nerves at lower leg level
0.697 0.302 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.697 0.303 0.000
H30 Chorioretinal inflammation
0.697 0.303 0.000
S06.8 Other intracranial injuries
0.696 0.303 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.696 0.304 0.000
S72.01 Fracture of neck of femur (open)
0.696 0.304 0.000
B80 Enterobiasis
0.696 0.304 0.000
S91.0 Open wound of ankle
0.695 0.305 0.000
S02.0 Fracture of vault of skull
0.695 0.305 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.694 0.305 0.000
H20 Iridocyclitis
0.694 0.306 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.692 0.308 0.000
S72.2 Subtrochanteric fracture
0.690 0.310 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.690 0.310 0.000
S82.40 Fracture of fibula alone (closed)
0.690 0.310 0.000
B00 Herpesviral [herpes simplex] infections
0.690 0.310 0.000
F05.9 Delirium, unspecified
0.689 0.311 0.000
W17 Other fall from one level to another
0.688 0.312 0.000
F60-F69 Disorders of adult personality and behaviour
0.688 0.312 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.688 0.312 0.000
I00-I02 Acute rheumatic fever
0.687 0.313 0.000
S98 Traumatic amputation of ankle and foot
0.687 0.313 0.000
S97 Crushing injury of ankle and foot
0.687 0.313 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.687 0.313 0.000
S95 Injury of blood vessels at ankle and foot level
0.687 0.313 0.000
S94 Injury of nerves at ankle and foot level
0.687 0.313 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.686 0.314 0.000
W06 Fall involving bed
0.686 0.314 0.000
I38 Endocarditis, valve unspecified
0.685 0.315 0.000
S82.50 Fracture of medial malleolus (closed)
0.685 0.315 0.000
E23 Hypofunction and other disorders of pituitary gland
0.684 0.316 0.000
G95 Other diseases of spinal cord
0.684 0.316 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.683 0.317 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.683 0.317 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.683 0.317 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.683 0.317 0.000
E11.0 With coma
0.683 0.317 0.000
S05 Injury of eye and orbit
0.681 0.319 0.000
H05 Disorders of orbit
0.681 0.319 0.000
G36 Other acute disseminated demyelination
0.681 0.319 0.000
W20-W49 Exposure to inanimate mechanical forces
0.680 0.320 0.000
H51 Other disorders of binocular movement
0.679 0.321 0.000
E10.5 With peripheral circulatory complications
0.679 0.321 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.679 0.321 0.000
W07.0 Home
0.679 0.321 0.000
S70 Superficial injury of hip and thigh
0.678 0.322 0.000
S02.1 Fracture of base of skull
0.678 0.322 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.678 0.322 0.000
B06 Rubella [German measles]
0.678 0.322 0.000
B05 Measles
0.678 0.322 0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions
0.678 0.322 0.000
B04 Monkeypox
0.678 0.322 0.000
B03 Smallpox
0.678 0.322 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.677 0.323 0.000
T98 Sequelae of other and unspecified effects of external causes
0.676 0.324 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.676 0.324 0.000
Q35-Q37 Cleft lip and cleft palate
0.676 0.324 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.676 0.324 0.000
S80 Superficial injury of lower leg
0.676 0.324 0.000
H13 Disorders of conjunctiva in diseases classified elsewhere
0.675 0.325 0.000
H10.9 Conjunctivitis, unspecified
0.675 0.325 0.000
H35.4 Peripheral retinal degeneration
0.674 0.326 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.674 0.326 0.000
H21 Other disorders of iris and ciliary body
0.674 0.326 0.000
H50.1 Divergent concomitant strabismus
0.674 0.326 0.000
I78 Diseases of capillaries
0.673 0.327 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.673 0.327 0.000
W10 Fall on and from stairs and steps
0.672 0.327 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.672 0.328 0.000
H11.8 Other specified disorders of conjunctiva
0.671 0.329 0.000
S82.9 Fracture of lower leg, part unspecified
0.670 0.330 0.000
S82.7 Multiple fractures of lower leg
0.670 0.330 0.000
F03 Unspecified dementia
0.669 0.331 0.000
H35.2 Other proliferative retinopathy
0.668 0.331 0.000
S92 Fracture of foot, except ankle
0.667 0.333 0.000
I74 Arterial embolism and thrombosis
0.666 0.334 0.000
E10.4 With neurological complications
0.666 0.334 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.666 0.334 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.665 0.335 0.000
T66-T78 Other and unspecified effects of external causes
0.664 0.335 0.000
A49 Bacterial infection of unspecified site
0.664 0.336 0.000
G64 Other disorders of peripheral nervous system
0.664 0.336 0.000
H52.3 Anisometropia and aniseikonia
0.664 0.336 0.000
W13 Fall from, out of or through building or structure
0.663 0.337 0.000
S20-S29 Injuries to the thorax
0.663 0.337 0.000
H35.5 Hereditary retinal dystrophy
0.662 0.338 0.000
H35.1 Retinopathy of prematurity
0.662 0.338 0.000
S64 Injury of nerves at wrist and hand level
0.662 0.338 0.000
J60-J70 Lung diseases due to external agents
0.661 0.339 0.000
H52.1 Myopia
0.659 0.341 0.000
J80 Adult respiratory distress syndrome
0.659 0.341 0.000
M84 Disorders of continuity of bone
0.659 0.341 0.000
I50.0 Congestive heart failure
0.659 0.341 0.000
T91 Sequelae of injuries of neck and trunk
0.659 0.341 0.000
H33 Retinal detachments and breaks
0.659 0.341 0.000
H16 Keratitis
0.658 0.342 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.658 0.342 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.658 0.342 0.000
B91 Sequelae of poliomyelitis
0.658 0.342 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.657 0.343 0.000
G60 Hereditary and idiopathic neuropathy
0.657 0.343 0.000
G90 Disorders of autonomic nervous system
0.656 0.344 0.000
S62 Fracture at wrist and hand level
0.656 0.344 0.000
S67 Crushing injury of wrist and hand
0.655 0.344 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.654 0.345 0.000
I25 Chronic ischaemic heart disease
0.654 0.346 0.000
Y84.0 Cardiac catheterisation
0.654 0.346 0.000
G72 Other myopathies
0.654 0.346 0.000
S82.00 Fracture of patella (closed)
0.653 0.347 0.000
Q83 Congenital malformations of breast
0.652 0.348 0.000
S09 Other and unspecified injuries of head
0.652 0.348 0.000
Q61.5 Medullary cystic kidney
0.651 0.349 0.000
E46 Unspecified protein-energy malnutrition
0.651 0.349 0.000
H17 Corneal scars and opacities
0.650 0.349 0.000
E29 Testicular dysfunction
0.650 0.350 0.000
Q50-Q56 Congenital malformations of genital organs
0.650 0.350 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.650 0.350 0.000
Y84.1 Kidney dialysis
0.650 0.350 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.649 0.351 0.000
S81.8 Open wound of other parts of lower leg
0.649 0.351 0.000
Y44 Agents primarily affecting blood constituents
0.648 0.352 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.648 0.352 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.647 0.352 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.647 0.353 0.000
Q00-Q07 Congenital malformations of the nervous system
0.647 0.353 0.000
A86 Unspecified viral encephalitis
0.647 0.353 0.000
Q65 Congenital deformities of hip
0.646 0.353 0.000
F80-F89 Disorders of psychological development
0.646 0.354 0.000
I05.0 Mitral stenosis
0.645 0.355 0.000
E27.1 Primary adrenocortical insufficiency
0.645 0.355 0.000
F30-F39 Mood [affective] disorders
0.645 0.355 0.000
S68 Traumatic amputation of wrist and hand
0.644 0.356 0.000
S69 Other and unspecified injuries of wrist and hand
0.644 0.356 0.000
T95 Sequelae of burns, corrosions and frostbite
0.644 0.356 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.644 0.356 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.644 0.356 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.644 0.356 0.000
B19 Unspecified viral hepatitis
0.643 0.357 0.000
B18 Chronic viral hepatitis
0.643 0.357 0.000
H61 Other disorders of external ear
0.642 0.358 0.000
Q61.2 Polycystic kidney, adult type
0.642 0.358 0.000
H04.9 Disorder of lachrymal system, unspecified
0.642 0.358 0.000
H04.8 Other disorders of lachrymal system
0.642 0.358 0.000
H04.6 Other changes in lachrymal passages
0.642 0.358 0.000
H04.4 Chronic inflammation of lachrymal passages
0.642 0.358 0.000
H04.3 Acute and unspecified inflammation of lachrymal passages
0.642 0.358 0.000
H04.0 Dacryoadenitis
0.642 0.358 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.639 0.361 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.639 0.361 0.000
H15 Disorders of sclera
0.639 0.361 0.000
S08 Traumatic amputation of part of head
0.638 0.361 0.000
S07 Crushing injury of head
0.638 0.361 0.000
S04 Injury of cranial nerves
0.638 0.361 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.638 0.361 0.000
G63.8 Polyneuropathy in other diseases classified elsewhere
0.638 0.362 0.000
G63.6 Polyneuropathy in other musculoskeletal disorders
0.638 0.362 0.000
G63.5 Polyneuropathy in systemic connective tissue disorders
0.638 0.362 0.000
G63.4 Polyneuropathy in nutritional deficiency
0.638 0.362 0.000
G63.3 Polyneuropathy in other endocrine and metabolic diseases
0.638 0.362 0.000
G63.1 Polyneuropathy in neoplastic disease
0.638 0.362 0.000
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere
0.638 0.362 0.000
G61 Inflammatory polyneuropathy
0.637 0.363 0.000
I23 Certain current complications following acute myocardial infarction
0.637 0.363 0.000
E28 Ovarian dysfunction
0.637 0.363 0.000
T87 Complications peculiar to reattachment and amputation
0.637 0.363 0.000
I09 Other rheumatic heart diseases
0.637 0.363 0.000
I06 Rheumatic aortic valve diseases
0.637 0.363 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.636 0.364 0.000
S89 Other and unspecified injuries of lower leg
0.636 0.364 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.636 0.364 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.635 0.365 0.000
E32 Diseases of thymus
0.635 0.365 0.000
E31 Polyglandular dysfunction
0.635 0.365 0.000
E30 Disorders of puberty, not elsewhere classified
0.635 0.365 0.000
E25 Adrenogenital disorders
0.635 0.365 0.000
E20 Hypoparathyroidism
0.635 0.365 0.000
E26 Hyperaldosteronism
0.635 0.365 0.000
S82.30 Fracture of lower end of tibia (closed)
0.635 0.365 0.000
T92.8 Sequelae of other specified injuries of upper limb
0.634 0.366 0.000
H18.9 Disorder of cornea, unspecified
0.634 0.366 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.633 0.367 0.000
G30 Alzheimer's disease
0.632 0.367 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.632 0.368 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.632 0.368 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.631 0.368 0.000
Y98 Lifestyle-related condition
0.631 0.368 0.000
Y97 Environmental-pollution-related condition
0.631 0.368 0.000
Y96 Work-related condition
0.631 0.368 0.000
J81 Pulmonary oedema
0.631 0.369 0.000
E13 Other specified diabetes mellitus
0.631 0.369 0.000
I05.9 Mitral valve disease, unspecified
0.631 0.369 0.000
Y84.4 Aspiration of fluid
0.630 0.369 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.629 0.370 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.629 0.371 0.000
I42 Cardiomyopathy
0.629 0.371 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.628 0.372 0.000
W18 Other fall on same level
0.627 0.372 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.627 0.372 0.000
W15 Fall from cliff
0.627 0.372 0.000
W14 Fall from tree
0.627 0.372 0.000
W12 Fall on and from scaffolding
0.627 0.372 0.000
W11 Fall on and from ladder
0.627 0.372 0.000
W09 Fall involving playground equipment
0.627 0.372 0.000
W08 Fall involving other furniture
0.627 0.372 0.000
W05 Fall involving wheelchair
0.627 0.372 0.000
W04 Fall while being carried or supported by other persons
0.627 0.372 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.627 0.372 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.627 0.372 0.000
W00 Fall on same level involving ice and snow
0.627 0.372 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.627 0.372 0.000
H11.0 Pterygium
0.627 0.373 0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb
0.627 0.373 0.000
A00-A09 Intestinal infectious diseases
0.627 0.373 0.000
M81.98 Osteoporosis, unspecified (Other)
0.627 0.373 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.627 0.373 0.000
G83 Other paralytic syndromes
0.627 0.373 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.627 0.373 0.000
G62 Other polyneuropathies
0.626 0.374 0.000
Y52 Agents primarily affecting the cardiovascular system
0.626 0.374 0.000
T93 Sequelae of injuries of lower limb
0.626 0.374 0.000
G96.0 Cerebrospinal fluid leak
0.625 0.374 0.000
H04.1 Other disorders of lachrymal gland
0.625 0.375 0.000
Y59 Other and unspecified vaccines and biological substances
0.624 0.376 0.000
Y58 Bacterial vaccines
0.624 0.376 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.624 0.376 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.624 0.376 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.624 0.376 0.000
Y48 Anaesthetics and therapeutic gases
0.624 0.376 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.624 0.376 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.624 0.376 0.000
H11.2 Conjunctival scars
0.624 0.376 0.000
H11.1 Conjunctival degenerations and deposits
0.624 0.376 0.000
H52.7 Disorder of refraction, unspecified
0.624 0.376 0.000
H52.6 Other disorders of refraction
0.624 0.376 0.000
H52.5 Disorders of accommodation
0.624 0.376 0.000
H52.4 Presbyopia
0.624 0.376 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.623 0.377 0.000
S06.9 Intracranial injury, unspecified
0.623 0.377 0.000
S06.80 Other intracranial injuries (without open intracranial wound)
0.622 0.378 0.000
S72.41 Fracture of lower end of femur (open)
0.622 0.378 0.000
Y84.2 Radiological procedure and radiotherapy
0.622 0.378 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.621 0.379 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.621 0.379 0.000
G92 Toxic encephalopathy
0.621 0.379 0.000
S91.7 Multiple open wounds of ankle and foot
0.621 0.379 0.000
S91.2 Open wound of toe(s) with damage to nail
0.621 0.379 0.000
S91.1 Open wound of toe(s) without damage to nail
0.621 0.379 0.000
S72.1 Pertrochanteric fracture
0.620 0.380 0.000
S42.2 Fracture of upper end of humerus
0.619 0.381 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.619 0.381 0.000
T86 Failure and rejection of transplanted organs and tissues
0.618 0.382 0.000
G03 Meningitis due to other and unspecified causes
0.617 0.383 0.000
F00 Dementia in Alzheimer's disease
0.617 0.383 0.000
I45.3 Trifascicular block
0.616 0.384 0.000
S02.00 Fracture of vault of skull (closed)
0.616 0.384 0.000
M60-M63 Disorders of muscles
0.616 0.384 0.000
S31 Open wound of abdomen, lower back and pelvis
0.615 0.384 0.000
S32 Fracture of lumbar spine and pelvis
0.614 0.386 0.000
S06.2 Diffuse brain injury
0.614 0.386 0.000
H34 Retinal vascular occlusions
0.614 0.386 0.000
B02 Zoster [herpes zoster]
0.613 0.387 0.000
I08.8 Other multiple valve diseases
0.613 0.387 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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