TreeWAS – Variant ID: rs75803315

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
I25 Chronic ischaemic heart disease	1.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000
I20 Angina pectoris	1.000	0.000
I20.9 Angina pectoris, unspecified	0.997	0.003
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.996	0.004
M20-M25 Other joint disorders	0.995	0.005
# Top node	0.993	0.007
Chapter IX Diseases of the circulatory system	0.993	0.007
I25.9 Chronic ischaemic heart disease, unspecified	0.988	0.012
M23 Internal derangement of knee	0.986	0.014
Chapter V Mental and behavioural disorders	0.985	0.015
M15-M19 Arthrosis	0.985	0.015
I25.1 Atherosclerotic heart disease	0.982	0.018
I25.8 Other forms of chronic ischaemic heart disease	0.979	0.021
M25 Other joint disorders, not elsewhere classified	0.974	0.026
F30-F39 Mood [affective] disorders	0.969	0.031
I20.0 Unstable angina	0.967	0.033
M25.5 Pain in joint	0.960	0.040
F33 Recurrent depressive disorder	0.960	0.040
M19 Other arthrosis	0.959	0.041
Chapter X Diseases of the respiratory system	0.956	0.044
M23.3 Other meniscus derangements	0.951	0.049
I24 Other acute ischaemic heart diseases	0.948	0.052
I30-I52 Other forms of heart disease	0.947	0.053
I25.2 Old myocardial infarction	0.939	0.061
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.939	0.061
M18 Arthrosis of first carpometacarpal joint	0.938	0.062
F33.1 Recurrent depressive disorder, current episode moderate	0.938	0.062
M19.9 Arthrosis, unspecified	0.933	0.067
F00-F09 Organic, including symptomatic, mental disorders	0.931	0.069
M23.2 Derangement of meniscus due to old tear or injury	0.930	0.070
M05-M14 Inflammatory polyarthropathies	0.921	0.079
M25.56 Pain in joint (Lower leg)	0.918	0.082
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.914	0.086
J80-J84 Other respiratory diseases principally affecting the interstitium	0.913	0.087
M19.99 Arthrosis, unspecified (Site unspecified)	0.911	0.089
F10 Mental and behavioural disorders due to use of alcohol	0.910	0.090
M10 Gout	0.904	0.096
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.901	0.099
M23.30 Other meniscus derangements (Multiple sites)	0.899	0.101
M10.9 Gout, unspecified	0.893	0.107
I24.8 Other forms of acute ischaemic heart disease	0.892	0.108
J95-J99 Other diseases of the respiratory system	0.891	0.109
M19.95 Arthrosis, unspecified (Pelvic region and thigh)	0.889	0.111
M24 Other specific joint derangements	0.889	0.111
J09-J18 Influenza and pneumonia	0.888	0.112
Chapter XX External causes of morbidity and mortality	0.888	0.112
F10.0 Acute intoxication	0.885	0.115
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.878	0.122
F33.9 Recurrent depressive disorder, unspecified	0.875	0.125
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.872	0.128
I50 Heart failure	0.872	0.128
Chapter I Certain infectious and parasitic diseases	0.867	0.133
F05 Delirium, not induced by alcohol and other psychoactive substances	0.863	0.137
M10.99 Gout, unspecified (Site unspecified)	0.860	0.140
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.858	0.142
I31 Other diseases of pericardium	0.858	0.142
M25.51 Pain in joint (Shoulder region)	0.858	0.142
I50.0 Congestive heart failure	0.852	0.148
I20.1 Angina pectoris with documented spasm	0.848	0.152
M25.9 Joint disorder, unspecified	0.842	0.158
M35 Other systemic involvement of connective tissue	0.836	0.164
M16 Coxarthrosis [arthrosis of hip]	0.824	0.176
I42 Cardiomyopathy	0.823	0.177
Chapter VIII Diseases of the ear and mastoid process	0.818	0.182
J60-J70 Lung diseases due to external agents	0.816	0.184
F05.9 Delirium, unspecified	0.814	0.186
J15 Bacterial pneumonia, not elsewhere classified	0.808	0.192
M30 Polyarteritis nodosa and related conditions	0.806	0.194
F30 Manic episode	0.805	0.194
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.805	0.195
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.805	0.195
J98 Other respiratory disorders	0.803	0.197
I25.5 Ischaemic cardiomyopathy	0.802	0.197
M25.52 Pain in joint (Upper arm)	0.801	0.199
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.799	0.201
I24.9 Acute ischaemic heart disease, unspecified	0.798	0.202
M25.4 Effusion of joint	0.796	0.204
J81 Pulmonary oedema	0.792	0.208
M65-M68 Disorders of synovium and tendon	0.789	0.211
Chapter VI Diseases of the nervous system	0.788	0.212
M16.0 Primary coxarthrosis, bilateral	0.788	0.212
I34 Nonrheumatic mitral valve disorders	0.787	0.213
J84 Other interstitial pulmonary diseases	0.786	0.214
M24.8 Other specific joint derangements, not elsewhere classified	0.786	0.214
I25.3 Aneurysm of heart	0.779	0.221
M25.53 Pain in joint (Forearm)	0.774	0.226
Chapter IV Endocrine, nutritional and metabolic diseases	0.768	0.232
I25.4 Coronary artery aneurysm	0.767	0.233
M70-M79 Other soft tissue disorders	0.765	0.235
I22 Subsequent myocardial infarction	0.764	0.236
M25.59 Pain in joint (Site unspecified)	0.761	0.239
G50-G59 Nerve, nerve root and plexus disorders	0.761	0.239
I31.3 Pericardial effusion (noninflammatory)	0.761	0.239
M24.2 Disorder of ligament	0.757	0.243
M23.5 Chronic instability of knee	0.757	0.243
M19.1 Posttraumatic arthrosis of other joints	0.757	0.243
J80 Adult respiratory distress syndrome	0.756	0.244
J98.1 Pulmonary collapse	0.752	0.248
F10.9 Unspecified mental and behavioural disorder	0.752	0.248
I25.0 Atherosclerotic cardiovascular disease, so described	0.751	0.248
M10.96 Gout, unspecified (Lower leg)	0.751	0.249
Q20-Q28 Congenital malformations of the circulatory system	0.751	0.249
J18 Pneumonia, organism unspecified	0.750	0.250
W50-W64 Exposure to animate mechanical forces	0.749	0.251
I47 Paroxysmal tachycardia	0.748	0.252
J13 Pneumonia due to Streptococcus pneumoniae	0.748	0.252
F10.1 Harmful use	0.747	0.253
M25.96 Joint disorder, unspecified (Lower leg)	0.747	0.253
F60-F69 Disorders of adult personality and behaviour	0.743	0.257
F39 Unspecified mood [affective] disorder	0.742	0.258
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.741	0.259
M60-M63 Disorders of muscles	0.738	0.262
M10.93 Gout, unspecified (Forearm)	0.737	0.263
F00 Dementia in Alzheimer's disease	0.737	0.263
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.736	0.264
M19.93 Arthrosis, unspecified (Forearm)	0.736	0.264
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.734	0.266
M11 Other crystal arthropathies	0.733	0.267
B15-B19 Viral hepatitis	0.733	0.267
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.732	0.268
M15 Polyarthrosis	0.730	0.270
A30-A49 Other bacterial diseases	0.729	0.271
W20-W49 Exposure to inanimate mechanical forces	0.728	0.272
M23.4 Loose body in knee	0.728	0.272
M25.8 Other specified joint disorders	0.727	0.273
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.727	0.273
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.726	0.274
J95 Postprocedural respiratory disorders, not elsewhere classified	0.724	0.276
M00-M03 Infectious arthropathies	0.723	0.276
M31 Other necrotising vasculopathies	0.723	0.277
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.723	0.277
M19.94 Arthrosis, unspecified (Hand)	0.723	0.277
I35 Nonrheumatic aortic valve disorders	0.722	0.278
I34.0 Mitral (valve) insufficiency	0.722	0.278
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.721	0.279
F10.5 Psychotic disorder	0.719	0.280
B35-B49 Mycoses	0.720	0.280
M25.54 Pain in joint (Hand)	0.719	0.281
V40-V49 Car occupant injured in transport accident	0.719	0.281
W00-W19 Falls	0.719	0.281
M70 Soft tissue disorders related to use, overuse and pressure	0.718	0.282
I42.2 Other hypertrophic cardiomyopathy	0.717	0.283
I25.6 Silent myocardial ischaemia	0.717	0.283
I23 Certain current complications following acute myocardial infarction	0.717	0.283
H65-H75 Diseases of middle ear and mastoid	0.716	0.284
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.715	0.284
M23.9 Internal derangement of knee, unspecified	0.715	0.285
H80-H83 Diseases of inner ear	0.715	0.285
I37 Pulmonary valve disorders	0.714	0.286
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.713	0.287
M33 Dermatopolymyositis	0.713	0.287
M32 Systemic lupus erythematosus	0.713	0.287
M16.7 Other secondary coxarthrosis	0.713	0.287
M91-M94 Chondropathies	0.713	0.287
I95-I99 Other and unspecified disorders of the circulatory system	0.712	0.288
Chapter XVI Certain conditions originating in the perinatal period	0.712	0.288
I00-I02 Acute rheumatic fever	0.712	0.288
I21 Acute myocardial infarction	0.712	0.288
G57 Mononeuropathies of lower limb	0.710	0.290
Q00-Q07 Congenital malformations of the nervous system	0.709	0.291
F34 Persistent mood [affective] disorders	0.708	0.292
G51 Facial nerve disorders	0.708	0.292
J15.2 Pneumonia due to staphylococcus	0.708	0.292
J15.1 Pneumonia due to Pseudomonas	0.707	0.293
M23.1 Discoid meniscus (congenital)	0.707	0.293
M23.0 Cystic meniscus	0.707	0.293
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.706	0.293
F70-F79 Mental retardation	0.706	0.293
I36 Nonrheumatic tricuspid valve disorders	0.706	0.294
F02 Dementia in other diseases classified elsewhere	0.704	0.296
F33.0 Recurrent depressive disorder, current episode mild	0.703	0.297
M23.8 Other internal derangements of knee	0.703	0.297
I47.2 Ventricular tachycardia	0.702	0.298
M35.0 Sicca syndrome [Sjogren]	0.699	0.301
M25.2 Flail joint	0.699	0.301
M25.1 Fistula of joint	0.699	0.301
M25.0 Haemarthrosis	0.699	0.301
M35.1 Other overlap syndromes	0.698	0.302
J18.0 Bronchopneumonia, unspecified	0.697	0.303
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.697	0.303
M25.58 Pain in joint (Other)	0.696	0.304
I31.9 Disease of pericardium, unspecified	0.696	0.304
W75-W84 Other accidental threats to breathing	0.696	0.304
I42.1 Obstructive hypertrophic cardiomyopathy	0.696	0.304
F38 Other mood [affective] disorders	0.695	0.305
Q50-Q56 Congenital malformations of genital organs	0.694	0.306
A80-A89 Viral infections of the central nervous system	0.694	0.306
M10.94 Gout, unspecified (Hand)	0.694	0.306
J82 Pulmonary eosinophilia, not elsewhere classified	0.693	0.307
M19.0 Primary arthrosis of other joints	0.693	0.307
J99 Respiratory disorders in diseases classified elsewhere	0.693	0.307
B00 Herpesviral [herpes simplex] infections	0.691	0.309
X20-X29 Contact with venomous animals and plants	0.689	0.311
F33.8 Other recurrent depressive disorders	0.688	0.312
F33.4 Recurrent depressive disorder, currently in remission	0.688	0.312
I33 Acute and subacute endocarditis	0.688	0.312
M19.8 Other specified arthrosis	0.687	0.313
M19.2 Other secondary arthrosis	0.687	0.313
M25.6 Stiffness of joint, not elsewhere classified	0.687	0.313
F01 Vascular dementia	0.684	0.316
E10-E14 Diabetes mellitus	0.684	0.316
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.683	0.317
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.682	0.318
M23.37 Other meniscus derangements-Capsular lig	0.681	0.318
X58-X59 Accidental exposure to other and unspecified factors	0.681	0.319
G57.6 Lesion of plantar nerve	0.680	0.320
I24.1 Dressler's syndrome	0.680	0.320
I52 Other heart disorders in diseases classified elsewhere	0.679	0.321
I48 Atrial fibrillation and flutter	0.679	0.321
I43 Cardiomyopathy in diseases classified elsewhere	0.679	0.321
I41 Myocarditis in diseases classified elsewhere	0.679	0.321
I40 Acute myocarditis	0.679	0.321
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.679	0.321
I32 Pericarditis in diseases classified elsewhere	0.679	0.321
X50-X57 Overexertion, travel and privation	0.679	0.321
F03 Unspecified dementia	0.679	0.321
V10-V19 Pedal cyclist injured in transport accident	0.677	0.323
I35.0 Aortic (valve) stenosis	0.676	0.324
J90-J94 Other diseases of pleura	0.674	0.326
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.673	0.327
F18 Mental and behavioural disorders due to use of volatile solvents	0.673	0.327
F16 Mental and behavioural disorders due to use of hallucinogens	0.673	0.327
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.673	0.327
F14 Mental and behavioural disorders due to use of cocaine	0.673	0.327
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.673	0.327
F11 Mental and behavioural disorders due to use of opioids	0.673	0.327
G51.0 Bell's palsy	0.673	0.327
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.672	0.328
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.672	0.328
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.672	0.328
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.672	0.328
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.668	0.332
M25.55 Pain in joint (Pelvic region and thigh)	0.668	0.332
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.668	0.332
F09 Unspecified organic or symptomatic mental disorder	0.668	0.332
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.668	0.332
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.666	0.333
F12 Mental and behavioural disorders due to use of cannabinoids	0.663	0.336
M10.97 Gout, unspecified (Ankle and foot)	0.663	0.336
I45 Other conduction disorders	0.663	0.337
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.662	0.338
J17 Pneumonia in diseases classified elsewhere	0.661	0.339
M21 Other acquired deformities of limbs	0.661	0.339
G30-G32 Other degenerative diseases of the nervous system	0.660	0.340
J20-J22 Other acute lower respiratory infections	0.660	0.340
M12 Other specific arthropathies	0.660	0.340
M09 Juvenile arthritis in diseases classified elsewhere	0.660	0.340
M08 Juvenile arthritis	0.660	0.340
E10 Insulin-dependent diabetes mellitus	0.659	0.341
M19.96 Arthrosis, unspecified-Lower leg	0.658	0.342
Q21 Congenital malformations of cardiac septa	0.656	0.344
G58 Other mononeuropathies	0.656	0.344
Q38-Q45 Other congenital malformations of the digestive system	0.656	0.344
M25.45 Effusion of joint (Pelvic region and thigh)	0.655	0.345
I51 Complications and ill-defined descriptions of heart disease	0.653	0.347
M24.5 Contracture of joint	0.653	0.347
M24.26 Disorder of ligament (Lower leg)	0.653	0.347
I30 Acute pericarditis	0.653	0.347
F10.8 Other mental and behavioural disorders	0.653	0.347
F10.7 Residual and late-onset psychotic disorder	0.653	0.347
F10.6 Amnesic syndrome	0.653	0.347
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.652	0.348
M35.7 Hypermobility syndrome	0.652	0.348
H81 Disorders of vestibular function	0.652	0.348
B90-B94 Sequelae of infectious and parasitic diseases	0.651	0.349
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.650	0.350
M10.4 Other secondary gout	0.648	0.351
M10.3 Gout due to impairment of renal function	0.648	0.351
M10.2 Drug-induced gout	0.648	0.351
M10.1 Lead-induced gout	0.648	0.351
M10.0 Idiopathic gout	0.648	0.351
Q80-Q89 Other congenital malformations	0.648	0.352
M25.47 Effusion of joint (Ankle and foot)	0.648	0.352
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.648	0.352
M25.3 Other instability of joint	0.648	0.352
B00.1 Herpesviral vesicular dermatitis	0.648	0.352
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.647	0.352
M14 Arthropathies in other diseases classified elsewhere	0.646	0.353
M05 Seropositive rheumatoid arthritis	0.646	0.353
H66 Suppurative and unspecified otitis media	0.647	0.353
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.646	0.354
Q35-Q37 Cleft lip and cleft palate	0.646	0.354
Q30-Q34 Congenital malformations of the respiratory system	0.646	0.354
F30.2 Mania with psychotic symptoms	0.645	0.355
X60-X84 Intentional self-harm	0.643	0.357
J69 Pneumonitis due to solids and liquids	0.643	0.357
I22.9 Subsequent myocardial infarction of unspecified site	0.643	0.357
E00-E07 Disorders of thyroid gland	0.643	0.357
B50-B64 Protozoal diseases	0.643	0.357
J84.1 Other interstitial pulmonary diseases with fibrosis	0.641	0.359
M23.6 Other spontaneous disruption of ligament(s) of knee	0.641	0.359
W06 Fall involving bed	0.641	0.359
F17 Mental and behavioural disorders due to use of tobacco	0.640	0.359
M10.98 Gout, unspecified (Other)	0.640	0.360
M10.95 Gout, unspecified (Pelvic region and thigh)	0.640	0.360
M10.92 Gout, unspecified (Upper arm)	0.640	0.360
M10.91 Gout, unspecified (Shoulder region)	0.640	0.360
M10.90 Gout, unspecified (Multiple sites)	0.640	0.360
Y40 Systemic antibiotics	0.640	0.360
J96 Respiratory failure, not elsewhere classified	0.639	0.361
I46 Cardiac arrest	0.639	0.361
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods	0.638	0.362
M24.9 Joint derangement, unspecified	0.637	0.363
M24.7 Protrusio acetabuli	0.637	0.363
M24.6 Ankylosis of joint	0.637	0.363
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.637	0.363
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.637	0.363
J12 Viral pneumonia, not elsewhere classified	0.637	0.363
J09 Influenza due to certain identified influenza virus	0.637	0.363
M30.0 Polyarteritis nodosa	0.637	0.363
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.636	0.363
Y35-Y36 Legal intervention and operations of war	0.636	0.363
Y10-Y34 Event of undetermined intent	0.636	0.363
Y00-Y09 Assault	0.636	0.363
X85-X99 Assault	0.636	0.363
X30-X39 Exposure to forces of nature	0.636	0.363
X10-X19 Contact with heat and hot substances	0.636	0.363
X00-X09 Exposure to smoke, fire and flames	0.636	0.363
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.636	0.363
W65-W74 Accidental drowning and submersion	0.636	0.363
V98-V99 Other and unspecified transport accidents	0.636	0.363
V95-V97 Air and space transport accidents	0.636	0.363
V90-V94 Water transport accidents	0.636	0.363
V70-V79 Bus occupant injured in transport accident	0.636	0.363
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.636	0.363
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.636	0.363
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.636	0.363
V01-V09 Pedestrian injured in transport accident	0.636	0.363
M65 Synovitis and tenosynovitis	0.637	0.363
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.634	0.366
J98.9 Respiratory disorder, unspecified	0.634	0.366
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.634	0.366
E20-E35 Disorders of other endocrine glands	0.634	0.366
V80-V89 Other land transport accidents	0.632	0.367
I34.2 Nonrheumatic mitral (valve) stenosis	0.631	0.368
F30.9 Manic episode, unspecified	0.630	0.370
I50.1 Left ventricular failure	0.630	0.370
B65-B83 Helminthiases	0.629	0.370
I21.9 Acute myocardial infarction, unspecified	0.628	0.372
M19.90 Arthrosis, unspecified (Multiple sites)	0.624	0.375
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.624	0.376
Y52 Agents primarily affecting the cardiovascular system	0.624	0.376
M19.01 Primary arthrosis of other joints (Shoulder region)	0.624	0.376
F80-F89 Disorders of psychological development	0.623	0.377
M34 Systemic sclerosis	0.622	0.378
B85-B89 Pediculosis, acariasis and other infestations	0.622	0.378
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.622	0.378
A75-A79 Rickettsioses	0.622	0.378
A70-A74 Other diseases caused by chlamydiae	0.622	0.378
A65-A69 Other spirochaetal diseases	0.622	0.378
A20-A28 Certain zoonotic bacterial diseases	0.622	0.378
A15-A19 Tuberculosis	0.622	0.378
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.621	0.379
J84.9 Interstitial pulmonary disease, unspecified	0.621	0.379
M25.86 Other specified joint disorders (Lower leg)	0.620	0.380
I20.8 Other forms of angina pectoris	0.620	0.380
F05.8 Other delirium	0.619	0.381
F05.1 Delirium superimposed on dementia	0.619	0.381
F05.0 Delirium not superimposed on dementia, so described	0.619	0.381
J18.9 Pneumonia, unspecified	0.619	0.381
F10.4 Withdrawal state with delirium	0.617	0.383
B15 Acute hepatitis A	0.617	0.383
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.616	0.384
I31.8 Other specified diseases of pericardium	0.615	0.385
I31.2 Haemopericardium, not elsewhere classified	0.615	0.385
I31.1 Chronic constrictive pericarditis	0.615	0.385
I31.0 Chronic adhesive pericarditis	0.615	0.385
M70.6 Trochanteric bursitis	0.614	0.386
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.613	0.387
J98.8 Other specified respiratory disorders	0.612	0.388
M16.3 Other dysplastic coxarthrosis	0.611	0.389
M76 Enthesopathies of lower limb, excluding foot	0.610	0.390
B25-B34 Other viral diseases	0.610	0.390
M24.0 Loose body in joint	0.609	0.391
Chapter XXII Codes for special purposes	0.605	0.394
B49 Unspecified mycosis	0.605	0.395
G58.9 Mononeuropathy, unspecified	0.604	0.396
M25.99 Joint disorder, unspecified (Site unspecified)	0.604	0.396
M25.98 Joint disorder, unspecified (Other)	0.604	0.396
M25.97 Joint disorder, unspecified (Ankle and foot)	0.604	0.396
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.604	0.396
M25.94 Joint disorder, unspecified (Hand)	0.604	0.396
M25.93 Joint disorder, unspecified (Forearm)	0.604	0.396
M25.92 Joint disorder, unspecified (Upper arm)	0.604	0.396
M25.91 Joint disorder, unspecified (Shoulder region)	0.604	0.396
M25.90 Joint disorder, unspecified (Multiple sites)	0.604	0.396
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.601	0.399
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.601	0.399
I95 Hypotension	0.600	0.400
F99-F99 Unspecified mental disorder	0.599	0.401
M11.2 Other chondrocalcinosis	0.599	0.401
M35.9 Systemic involvement of connective tissue, unspecified	0.599	0.401
M35.8 Other specified systemic involvement of connective tissue	0.599	0.401
M35.6 Relapsing panniculitis [Weber-Christian]	0.599	0.401
M35.5 Multifocal fibrosclerosis	0.599	0.401
M35.4 Diffuse (eosinophilic) fasciitis	0.599	0.401
M35.2 Behcet's disease	0.599	0.401
I42.9 Cardiomyopathy, unspecified	0.599	0.401
H66.9 Otitis media, unspecified	0.598	0.402
F00.9 Dementia in Alzheimer's disease, unspecified	0.598	0.402
I42.8 Other cardiomyopathies	0.597	0.403
M19.13 Post-traumatic arthrosis of other joints (Forearm)	0.597	0.403
I38 Endocarditis, valve unspecified	0.596	0.404
G00-G09 Inflammatory diseases of the central nervous system	0.596	0.404
J84.8 Other specified interstitial pulmonary diseases	0.596	0.404
Q60-Q64 Congenital malformations of the urinary system	0.595	0.405
M24.1 Other articular cartilage disorders	0.595	0.405
H69 Other disorders of Eustachian tube	0.593	0.407
W20 Struck by thrown, projected or falling object	0.593	0.407
B18 Chronic viral hepatitis	0.592	0.408
M16.6 Other secondary coxarthrosis, bilateral	0.591	0.409
M16.5 Other posttraumatic coxarthrosis	0.591	0.409
M16.4 Posttraumatic coxarthrosis, bilateral	0.591	0.409
M16.2 Coxarthrosis resulting from dysplasia, bilateral	0.591	0.409
W60 Contact with plant thorns and spines and sharp leaves	0.590	0.410
I42.7 Cardiomyopathy due to drugs and other external agents	0.590	0.410
I42.5 Other restrictive cardiomyopathy	0.590	0.410
I42.4 Endocardial fibroelastosis	0.590	0.410
I42.3 Endomyocardial (eosinophilic) disease	0.590	0.410
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.589	0.411
M22 Disorders of patella	0.589	0.411
M40-M43 Deforming dorsopathies	0.589	0.411
F30.0 Hypomania	0.589	0.411
G30 Alzheimer's disease	0.589	0.411
F69 Unspecified disorder of adult personality and behaviour	0.588	0.412
M70.4 Prepatellar bursitis	0.587	0.413
Q21.1 Atrial septal defect	0.586	0.414
J10 Influenza due to identified influenza virus	0.585	0.414
J70 Respiratory conditions due to other external agents	0.585	0.415
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours	0.585	0.415
J67 Hypersensitivity pneumonitis due to organic dust	0.585	0.415
J66 Airway disease due to specific organic dust	0.585	0.415
J63 Pneumoconiosis due to other inorganic dusts	0.585	0.415
J62 Pneumoconiosis due to dust containing silica	0.585	0.415
J65 Pneumoconiosis associated with tuberculosis	0.585	0.415
J64 Unspecified pneumoconiosis	0.585	0.415
J60 Coalworker's pneumoconiosis	0.585	0.415
V49 Car occupant injured in other and unspecified transport accidents	0.585	0.415
M19.11 Post-traumatic arthrosis of other joints (Shoulder region)	0.585	0.415
W25 Contact with sharp glass	0.585	0.415
J98.5 Diseases of mediastinum, not elsewhere classified	0.584	0.416
M19.92 Arthrosis, unspecified (Upper arm)	0.584	0.416
E14 Unspecified diabetes mellitus	0.584	0.416
J95.0 Tracheostomy malfunction	0.583	0.417
S50-S59 Injuries to the elbow and forearm	0.582	0.418
M77 Other enthesopathies	0.581	0.419
M96.0 Pseudarthrosis after fusion or arthrodesis	0.581	0.419
Q65 Congenital deformities of hip	0.580	0.420
J15.9 Bacterial pneumonia, unspecified	0.579	0.421
J15.8 Other bacterial pneumonia	0.579	0.421
J15.6 Pneumonia due to other aerobic Gram-negative bacteria	0.579	0.421
J15.5 Pneumonia due to Escherichia coli	0.579	0.421
J15.4 Pneumonia due to other streptococci	0.579	0.421
J15.3 Pneumonia due to streptococcus, group B	0.579	0.421
G54 Nerve root and plexus disorders	0.579	0.421
I42.6 Alcoholic cardiomyopathy	0.579	0.421
A40 Streptococcal septicaemia	0.578	0.421
A50-A64 Infections with a predominantly sexual mode of transmission	0.578	0.422
M30.8 Other conditions related to polyarteritis nodosa	0.578	0.422
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.578	0.422
M30.2 Juvenile polyarteritis	0.578	0.422
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified	0.578	0.422
F30.8 Other manic episodes	0.577	0.422
F30.1 Mania without psychotic symptoms	0.577	0.422
M99 Biomechanical lesions, not elsewhere classified	0.577	0.422
M70.2 Olecranon bursitis	0.577	0.423
J98.6 Disorders of diaphragm	0.575	0.424
J98.3 Compensatory emphysema	0.575	0.424
J98.2 Interstitial emphysema	0.575	0.424
F10.2 Dependence syndrome	0.575	0.425
J15.0 Pneumonia due to Klebsiella pneumoniae	0.574	0.426
A00-A09 Intestinal infectious diseases	0.574	0.426
M24.23 Disorder of ligament (Forearm)	0.573	0.427
V20-V29 Motorcycle rider injured in transport accident	0.573	0.427
M96.8 Other postprocedural musculoskeletal disorders	0.573	0.427
X40-X49 Accidental poisoning by and exposure to noxious substances	0.572	0.428
A41 Other septicaemia	0.572	0.428
F64 Gender identity disorders	0.571	0.429
E10.9 Without complications	0.571	0.429
M25.49 Effusion of joint (Site unspecified)	0.571	0.429
M25.48 Effusion of joint (Other)	0.571	0.429
M25.44 Effusion of joint (Hand)	0.571	0.429
M25.43 Effusion of joint (Forearm)	0.571	0.429
M25.42 Effusion of joint (Upper arm)	0.571	0.429
M25.41 Effusion of joint (Shoulder region)	0.571	0.429
M25.40 Effusion of joint (Multiple sites)	0.571	0.429
Q05 Spina bifida	0.571	0.429
M66 Spontaneous rupture of synovium and tendon	0.570	0.429
M70.5 Other bursitis of knee	0.570	0.430
Y60-Y69 Misadventures to patients during surgical and medical care	0.570	0.430
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.569	0.431
H81.2 Vestibular neuronitis	0.569	0.431
W10 Fall on and from stairs and steps	0.568	0.432
B20-B24 Human immunodeficiency virus [HIV] disease	0.567	0.432
H74 Other disorders of middle ear and mastoid	0.567	0.433
M86-M90 Other osteopathies	0.567	0.433
I27 Other pulmonary heart diseases	0.567	0.433
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.567	0.433
M67 Other disorders of synovium and tendon	0.566	0.434

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations