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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs76087002
log Bayes Factor = 13.692
Chromosome 4   position 187,555,428  (GRCh37) Explore rs76087002 on Ensembl!
Variant rs76087002 is part of Cluster X0111

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
0.998 0.002 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.993 0.007 0.000
J40-J47 Chronic lower respiratory diseases
0.988 0.012 0.000
Chapter XX External causes of morbidity and mortality
0.988 0.012 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.985 0.015 0.000
F30-F39 Mood [affective] disorders
0.984 0.016 0.000
Chapter VI Diseases of the nervous system
0.982 0.018 0.000
J44 Other chronic obstructive pulmonary disease
0.968 0.032 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.967 0.033 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.966 0.034 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.966 0.034 0.000
J09-J18 Influenza and pneumonia
0.965 0.035 0.000
G40-G47 Episodic and paroxysmal disorders
0.958 0.042 0.000
F41 Other anxiety disorders
0.956 0.044 0.000
S60-S69 Injuries to the wrist and hand
0.954 0.046 0.000
H43-H45 Disorders of vitreous body and globe
0.949 0.051 0.000
O42 Premature rupture of membranes
0.947 0.053 0.000
F32 Depressive episode
0.947 0.053 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.940 0.060 0.000
Chapter IX Diseases of the circulatory system
0.935 0.065 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.932 0.068 0.000
Y43 Primarily systemic agents
0.931 0.069 0.000
H25-H28 Disorders of lens
0.930 0.070 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.927 0.073 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.923 0.077 0.000
F33 Recurrent depressive disorder
0.922 0.078 0.000
F41.9 Anxiety disorder, unspecified
0.919 0.081 0.000
H43 Disorders of vitreous body
0.919 0.081 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.917 0.083 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.912 0.088 0.000
H53-H54 Visual disturbances and blindness
0.912 0.088 0.000
O42.9 Premature rupture of membranes, unspecified
0.912 0.088 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.911 0.089 0.000
S70-S79 Injuries to the hip and thigh
0.905 0.095 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.901 0.099 0.000
S40-S49 Injuries to the shoulder and upper arm
0.894 0.106 0.000
I80 Phlebitis and thrombophlebitis
0.894 0.106 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.893 0.107 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.893 0.107 0.000
Chapter II Neoplasms
0.892 0.108 0.000
H40-H42 Glaucoma
0.890 0.110 0.000
Chapter XIV Diseases of the genitourinary system
0.888 0.112 0.000
J95-J99 Other diseases of the respiratory system
0.883 0.117 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.880 0.120 0.000
G43 Migraine
0.880 0.120 0.000
O00-O08 Pregnancy with abortive outcome
0.879 0.121 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.877 0.123 0.000
J18 Pneumonia, organism unspecified
0.876 0.124 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.871 0.129 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.871 0.129 0.000
H02 Other disorders of eyelid
0.870 0.130 0.000
Y52 Agents primarily affecting the cardiovascular system
0.864 0.136 0.000
Chapter VIII Diseases of the ear and mastoid process
0.861 0.139 0.000
Y43.3 Other antineoplastic drugs
0.861 0.139 0.000
H55-H59 Other disorders of eye and adnexa
0.860 0.140 0.000
I30-I52 Other forms of heart disease
0.857 0.143 0.000
C64-C68 Malignant neoplasms of urinary tract
0.849 0.151 0.000
N20-N23 Urolithiasis
0.849 0.151 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.848 0.152 0.000
O80-O84 Delivery
0.848 0.152 0.000
J20-J22 Other acute lower respiratory infections
0.845 0.155 0.000
F32.1 Moderate depressive episode
0.842 0.158 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.840 0.160 0.000
N17-N19 Renal failure
0.836 0.164 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.834 0.166 0.000
J40 Bronchitis, not specified as acute or chronic
0.833 0.167 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.832 0.168 0.000
V40-V49 Car occupant injured in transport accident
0.831 0.169 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.828 0.172 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.828 0.172 0.000
H43.8 Other disorders of vitreous body
0.826 0.174 0.000
I45 Other conduction disorders
0.826 0.174 0.000
H25 Senile cataract
0.825 0.175 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.825 0.175 0.000
G44 Other headache syndromes
0.824 0.176 0.000
F20 Schizophrenia
0.823 0.177 0.000
G20-G26 Extrapyramidal and movement disorders
0.823 0.177 0.000
J18.0 Bronchopneumonia, unspecified
0.823 0.177 0.000
F32.9 Depressive episode, unspecified
0.823 0.177 0.000
T66-T78 Other and unspecified effects of external causes
0.822 0.178 0.000
S20-S29 Injuries to the thorax
0.822 0.178 0.000
N23 Unspecified renal colic
0.820 0.180 0.000
S61 Open wound of wrist and hand
0.819 0.181 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.818 0.182 0.000
S62 Fracture at wrist and hand level
0.817 0.183 0.000
T93 Sequelae of injuries of lower limb
0.816 0.184 0.000
H02.4 Ptosis of eyelid
0.815 0.185 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.815 0.185 0.000
G43.1 Migraine with aura [classical migraine]
0.815 0.185 0.000
Chapter XXII Codes for special purposes
0.814 0.186 0.000
J10 Influenza due to identified influenza virus
0.812 0.188 0.000
H40 Glaucoma
0.812 0.188 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.811 0.189 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.811 0.189 0.000
G40 Epilepsy
0.809 0.191 0.000
T79-T79 Certain early complications of trauma
0.809 0.191 0.000
H43.1 Vitreous haemorrhage
0.802 0.198 0.000
C67 Malignant neoplasm of bladder
0.801 0.199 0.000
Y43.0 Antiallergic and antiemetic drugs
0.798 0.202 0.000
G35 Multiple sclerosis
0.798 0.202 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.798 0.202 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.798 0.202 0.000
N18 Chronic renal failure
0.797 0.203 0.000
S42 Fracture of shoulder and upper arm
0.797 0.203 0.000
I51 Complications and ill-defined descriptions of heart disease
0.796 0.204 0.000
H53 Visual disturbances
0.795 0.205 0.000
N00-N08 Glomerular diseases
0.793 0.207 0.000
J90-J94 Other diseases of pleura
0.792 0.208 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.790 0.210 0.000
J45 Asthma
0.789 0.211 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.789 0.211 0.000
O85-O92 Complications predominantly related to the puerperium
0.788 0.212 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.788 0.212 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.787 0.213 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.787 0.213 0.000
H43.3 Other vitreous opacities
0.786 0.214 0.000
Q00-Q07 Congenital malformations of the nervous system
0.785 0.215 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.783 0.217 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.783 0.217 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.782 0.218 0.000
H02.1 Ectropion of eyelid
0.780 0.220 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.780 0.220 0.000
Y40 Systemic antibiotics
0.778 0.222 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.776 0.223 0.000
T91 Sequelae of injuries of neck and trunk
0.776 0.224 0.000
J47 Bronchiectasis
0.776 0.224 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.776 0.224 0.000
S10-S19 Injuries to the neck
0.776 0.224 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.775 0.225 0.000
O82 Single delivery by Caesarean section
0.774 0.226 0.000
I45.1 Other and unspecified right bundle-branch block
0.774 0.226 0.000
S70 Superficial injury of hip and thigh
0.774 0.226 0.000
W00-W19 Falls
0.773 0.226 0.000
H27 Other disorders of lens
0.773 0.227 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.773 0.227 0.000
H54 Blindness and low vision
0.773 0.227 0.000
H65-H75 Diseases of middle ear and mastoid
0.773 0.227 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.771 0.229 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.770 0.230 0.000
Q60-Q64 Congenital malformations of the urinary system
0.768 0.232 0.000
C15-C26 Malignant neoplasms of digestive organs
0.765 0.235 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.763 0.237 0.000
W50-W64 Exposure to animate mechanical forces
0.762 0.237 0.000
J42 Unspecified chronic bronchitis
0.762 0.238 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.761 0.239 0.000
S00-S09 Injuries to the head
0.760 0.240 0.000
I50 Heart failure
0.758 0.242 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.757 0.243 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.757 0.243 0.000
I42 Cardiomyopathy
0.756 0.244 0.000
I51.8 Other ill-defined heart diseases
0.754 0.246 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.754 0.246 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.751 0.249 0.000
I81 Portal vein thrombosis
0.751 0.249 0.000
N18.3 Chronic kidney disease, stage 3
0.751 0.249 0.000
Y44 Agents primarily affecting blood constituents
0.750 0.250 0.000
F22 Persistent delusional disorders
0.750 0.250 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.750 0.250 0.000
C45 Mesothelioma
0.748 0.252 0.000
H25.8 Other senile cataract
0.748 0.252 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.748 0.252 0.000
S72 Fracture of femur
0.747 0.253 0.000
H30-H36 Disorders of choroid and retina
0.747 0.253 0.000
E00-E07 Disorders of thyroid gland
0.747 0.253 0.000
S62.6 Fracture of other finger
0.747 0.253 0.000
J14 Pneumonia due to Haemophilus influenzae
0.746 0.253 0.000
H02.5 Other disorders affecting eyelid function
0.746 0.254 0.000
T90 Sequelae of injuries of head
0.746 0.254 0.000
E10-E14 Diabetes mellitus
0.745 0.255 0.000
S60 Superficial injury of wrist and hand
0.745 0.255 0.000
H55 Nystagmus and other irregular eye movements
0.744 0.256 0.000
F25 Schizoaffective disorders
0.743 0.256 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.743 0.257 0.000
G47 Sleep disorders
0.742 0.258 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.741 0.259 0.000
O36 Maternal care for other known or suspected foetal problems
0.741 0.259 0.000
N76 Other inflammation of vagina and vulva
0.741 0.259 0.000
G25 Other extrapyramidal and movement disorders
0.740 0.260 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.738 0.262 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.737 0.263 0.000
C67.9 Bladder, unspecified
0.737 0.263 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.737 0.263 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.736 0.264 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.736 0.264 0.000
F33.9 Recurrent depressive disorder, unspecified
0.735 0.265 0.000
H90-H95 Other disorders of ear
0.735 0.265 0.000
S69 Other and unspecified injuries of wrist and hand
0.735 0.265 0.000
I10-I15 Hypertensive diseases
0.734 0.266 0.000
J22 Unspecified acute lower respiratory infection
0.734 0.266 0.000
H40.9 Glaucoma, unspecified
0.734 0.266 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.731 0.269 0.000
V10-V19 Pedal cyclist injured in transport accident
0.731 0.269 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.730 0.270 0.000
H21 Other disorders of iris and ciliary body
0.729 0.271 0.000
T59 Toxic effect of other gases, fumes and vapours
0.728 0.272 0.000
Q50-Q56 Congenital malformations of genital organs
0.727 0.273 0.000
G37 Other demyelinating diseases of central nervous system
0.726 0.274 0.000
J30-J39 Other diseases of upper respiratory tract
0.726 0.274 0.000
Y45.1 Salicylates
0.725 0.275 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.724 0.276 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.724 0.276 0.000
Q80-Q89 Other congenital malformations
0.724 0.276 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.723 0.277 0.000
F80-F89 Disorders of psychological development
0.722 0.278 0.000
O02 Other abnormal products of conception
0.721 0.279 0.000
H10-H13 Disorders of conjunctiva
0.721 0.279 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.721 0.279 0.000
I50.9 Heart failure, unspecified
0.721 0.279 0.000
E10 Insulin-dependent diabetes mellitus
0.719 0.281 0.000
H26 Other cataract
0.718 0.282 0.000
T87 Complications peculiar to reattachment and amputation
0.718 0.282 0.000
S61.0 Open wound of finger(s) without damage to nail
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.716 0.284 0.000
F99-F99 Unspecified mental disorder
0.716 0.284 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.284 0.000
F70-F79 Mental retardation
0.716 0.284 0.000
Y52.1 Calcium-channel blockers
0.714 0.286 0.000
O43 Placental disorders
0.713 0.287 0.000
F60-F69 Disorders of adult personality and behaviour
0.713 0.287 0.000
T43.2 Other and unspecified antidepressants
0.713 0.287 0.000
G90-G99 Other disorders of the nervous system
0.713 0.287 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.711 0.289 0.000
I05-I09 Chronic rheumatic heart diseases
0.711 0.289 0.000
X60-X84 Intentional self-harm
0.709 0.291 0.000
O03 Spontaneous abortion
0.709 0.291 0.000
J41 Simple and mucopurulent chronic bronchitis
0.709 0.291 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.709 0.291 0.000
Y35-Y36 Legal intervention and operations of war
0.709 0.291 0.000
Y10-Y34 Event of undetermined intent
0.709 0.291 0.000
Y00-Y09 Assault
0.709 0.291 0.000
X85-X99 Assault
0.709 0.291 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.709 0.291 0.000
X50-X57 Overexertion, travel and privation
0.709 0.291 0.000
X30-X39 Exposure to forces of nature
0.709 0.291 0.000
X20-X29 Contact with venomous animals and plants
0.709 0.291 0.000
X10-X19 Contact with heat and hot substances
0.709 0.291 0.000
X00-X09 Exposure to smoke, fire and flames
0.709 0.291 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.709 0.291 0.000
W75-W84 Other accidental threats to breathing
0.709 0.291 0.000
W65-W74 Accidental drowning and submersion
0.709 0.291 0.000
V98-V99 Other and unspecified transport accidents
0.709 0.291 0.000
V95-V97 Air and space transport accidents
0.709 0.291 0.000
V90-V94 Water transport accidents
0.709 0.291 0.000
V80-V89 Other land transport accidents
0.709 0.291 0.000
V70-V79 Bus occupant injured in transport accident
0.709 0.291 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.709 0.291 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.709 0.291 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.709 0.291 0.000
V01-V09 Pedestrian injured in transport accident
0.709 0.291 0.000
O23 Infections of genito-urinary tract in pregnancy
0.708 0.292 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.708 0.292 0.000
O82.0 Delivery by elective Caesarean section
0.708 0.292 0.000
Y59 Other and unspecified vaccines and biological substances
0.706 0.294 0.000
Y58 Bacterial vaccines
0.706 0.294 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.706 0.294 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.706 0.294 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.706 0.294 0.000
Y48 Anaesthetics and therapeutic gases
0.706 0.294 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.706 0.294 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.706 0.294 0.000
S67 Crushing injury of wrist and hand
0.706 0.294 0.000
F38 Other mood [affective] disorders
0.705 0.295 0.000
F34 Persistent mood [affective] disorders
0.705 0.295 0.000
F30 Manic episode
0.705 0.295 0.000
F39 Unspecified mood [affective] disorder
0.705 0.295 0.000
Y57 Other and unspecified drugs and medicaments
0.705 0.295 0.000
E10.9 Without complications
0.704 0.296 0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified
0.702 0.298 0.000
S50-S59 Injuries to the elbow and forearm
0.702 0.298 0.000
N19 Unspecified renal failure
0.702 0.298 0.000
N76.4 Abscess of vulva
0.702 0.298 0.000
O00 Ectopic pregnancy
0.702 0.298 0.000
F42 Obsessive-compulsive disorder
0.700 0.300 0.000
H02.8 Other specified disorders of eyelid
0.700 0.300 0.000
I45.9 Conduction disorder, unspecified
0.699 0.301 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.699 0.301 0.000
Q66 Congenital deformities of feet
0.697 0.303 0.000
S90-S99 Injuries to the ankle and foot
0.696 0.304 0.000
I87 Other disorders of veins
0.696 0.304 0.000
F29 Unspecified nonorganic psychosis
0.696 0.304 0.000
T78 Adverse effects, not elsewhere classified
0.695 0.305 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.695 0.305 0.000
H74 Other disorders of middle ear and mastoid
0.694 0.306 0.000
O45 Premature separation of placenta [abruptio placentae]
0.693 0.307 0.000
O44 Placenta praevia
0.693 0.307 0.000
O41 Other disorders of amniotic fluid and membranes
0.693 0.307 0.000
O33 Maternal care for known or suspected disproportion
0.693 0.307 0.000
O31 Complications specific to multiple gestation
0.693 0.307 0.000
F48 Other neurotic disorders
0.693 0.307 0.000
F44 Dissociative [conversion] disorders
0.693 0.307 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.693 0.307 0.000
Q35-Q37 Cleft lip and cleft palate
0.693 0.307 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.693 0.307 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.693 0.307 0.000
J60-J70 Lung diseases due to external agents
0.692 0.308 0.000
J17 Pneumonia in diseases classified elsewhere
0.692 0.308 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.692 0.308 0.000
J12 Viral pneumonia, not elsewhere classified
0.692 0.308 0.000
J09 Influenza due to certain identified influenza virus
0.692 0.308 0.000
T56 Toxic effect of metals
0.691 0.308 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.691 0.309 0.000
O21 Excessive vomiting in pregnancy
0.690 0.310 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.690 0.310 0.000
H18 Other disorders of cornea
0.690 0.310 0.000
F20.9 Schizophrenia, unspecified
0.689 0.310 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.689 0.311 0.000
F20.0 Paranoid schizophrenia
0.688 0.312 0.000
T93.2 Sequelae of other fractures of lower limb
0.688 0.312 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.687 0.313 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.687 0.313 0.000
G41 Status epilepticus
0.687 0.313 0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.686 0.314 0.000
F41.8 Other specified anxiety disorders
0.685 0.315 0.000
F41.3 Other mixed anxiety disorders
0.685 0.315 0.000
S42.2 Fracture of upper end of humerus
0.685 0.315 0.000
S65 Injury of blood vessels at wrist and hand level
0.684 0.316 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.684 0.316 0.000
H16 Keratitis
0.684 0.316 0.000
V48 Car occupant injured in noncollision transport accident
0.683 0.317 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.681 0.319 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.681 0.319 0.000
G44.2 Tension-type headache
0.681 0.319 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.680 0.319 0.000
O30 Multiple gestation
0.680 0.320 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.680 0.320 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.680 0.320 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.679 0.321 0.000
O42.2 Premature rupture of membranes, labour delayed by therapy
0.679 0.321 0.000
S70.9 Superficial injury of hip and thigh, unspecified
0.679 0.321 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.679 0.321 0.000
O40 Polyhydramnios
0.679 0.321 0.000
F32.8 Other depressive episodes
0.679 0.321 0.000
F32.0 Mild depressive episode
0.679 0.321 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.678 0.322 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.678 0.322 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.677 0.323 0.000
S62.61 Fracture of other finger (open)
0.677 0.323 0.000
O46.9 Antepartum haemorrhage, unspecified
0.677 0.323 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.676 0.324 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.675 0.325 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.675 0.325 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.675 0.325 0.000
G24 Dystonia
0.674 0.326 0.000
S68 Traumatic amputation of wrist and hand
0.674 0.326 0.000
H53.4 Visual field defects
0.673 0.327 0.000
T85.2 Mechanical complication of intraocular lens
0.672 0.328 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.672 0.328 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.672 0.328 0.000
S71 Open wound of hip and thigh
0.671 0.329 0.000
C20 Malignant neoplasm of rectum
0.671 0.329 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.671 0.329 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.671 0.329 0.000
S79 Other and unspecified injuries of hip and thigh
0.671 0.329 0.000
I00-I02 Acute rheumatic fever
0.670 0.330 0.000
T91.3 Sequelae of injury of spinal cord
0.669 0.331 0.000
F23 Acute and transient psychotic disorders
0.668 0.332 0.000
F28 Other nonorganic psychotic disorders
0.668 0.332 0.000
F24 Induced delusional disorder
0.668 0.332 0.000
F21 Schizotypal disorder
0.668 0.332 0.000
I89.0 Lymphoedema, not elsewhere classified
0.668 0.332 0.000
Y43.9 Primarily systemic agent, unspecified
0.667 0.332 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.667 0.332 0.000
Y43.6 Enzymes, not elsewhere classified
0.667 0.332 0.000
Y43.5 Acidifying and alkalising agents
0.667 0.332 0.000
Y43.2 Antineoplastic natural products
0.667 0.332 0.000
Y43.1 Antineoplastic antimetabolites
0.667 0.332 0.000
C67.6 Ureteric orifice
0.667 0.333 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.667 0.333 0.000
G44.8 Other specified headache syndromes
0.667 0.333 0.000
H17 Corneal scars and opacities
0.666 0.334 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.666 0.334 0.000
G43.9 Migraine, unspecified
0.666 0.334 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.665 0.335 0.000
H53.0 Amblyopia ex anopsia
0.665 0.335 0.000
J98 Other respiratory disorders
0.665 0.335 0.000
V20-V29 Motorcycle rider injured in transport accident
0.665 0.335 0.000
T17 Foreign body in respiratory tract
0.665 0.335 0.000
T98 Sequelae of other and unspecified effects of external causes
0.664 0.336 0.000
T95 Sequelae of burns, corrosions and frostbite
0.664 0.336 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.664 0.336 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.664 0.336 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.664 0.336 0.000
N70 Salpingitis and oophoritis
0.664 0.336 0.000
C45.7 Mesothelioma of other sites
0.663 0.337 0.000
J45.0 Predominantly allergic asthma
0.663 0.337 0.000
H04 Disorders of lachrymal system
0.663 0.337 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.662 0.338 0.000
T88.4 Failed or difficult intubation
0.662 0.338 0.000
J11 Influenza, virus not identified
0.662 0.338 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.662 0.338 0.000
J99.1 Respiratory disorders in other diffuse connective tissue disorders
0.661 0.339 0.000
F33.8 Other recurrent depressive disorders
0.661 0.339 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.661 0.339 0.000
W20-W49 Exposure to inanimate mechanical forces
0.660 0.340 0.000
F43 Reaction to severe stress, and adjustment disorders
0.660 0.340 0.000
H43.9 Disorder of vitreous body, unspecified
0.659 0.341 0.000
H43.2 Crystalline deposits in vitreous body
0.659 0.341 0.000
H43.0 Vitreous prolapse
0.659 0.341 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.659 0.341 0.000
N21 Calculus of lower urinary tract
0.658 0.342 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.658 0.342 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.657 0.343 0.000
T16 Foreign body in ear
0.657 0.343 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.656 0.343 0.000
S00 Superficial injury of head
0.656 0.344 0.000
F41.1 Generalised anxiety disorder
0.655 0.345 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.655 0.345 0.000
S61.1 Open wound of finger(s) with damage to nail
0.655 0.345 0.000
N18.9 Chronic renal failure, unspecified
0.655 0.345 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.654 0.345 0.000
G30-G32 Other degenerative diseases of the nervous system
0.654 0.346 0.000
H05 Disorders of orbit
0.653 0.346 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.653 0.346 0.000
I49 Other cardiac arrhythmias
0.653 0.347 0.000
H40.5 Glaucoma secondary to other eye disorders
0.653 0.347 0.000
H57 Other disorders of eye and adnexa
0.653 0.347 0.000
D37.1 Stomach
0.653 0.347 0.000
J18.9 Pneumonia, unspecified
0.653 0.347 0.000
I37 Pulmonary valve disorders
0.652 0.348 0.000
I77 Other disorders of arteries and arterioles
0.652 0.348 0.000
J46 Status asthmaticus
0.651 0.349 0.000
G70-G73 Diseases of myoneural junction and muscle
0.650 0.349 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.650 0.350 0.000
V49 Car occupant injured in other and unspecified transport accidents
0.650 0.350 0.000
N10-N16 Renal tubulo-interstitial diseases
0.650 0.350 0.000
H01 Other inflammation of eyelid
0.650 0.350 0.000
T51 Toxic effect of alcohol
0.650 0.350 0.000
Q76 Congenital malformations of spine and bony thorax
0.650 0.350 0.000
D37.5 Rectum
0.649 0.351 0.000
S78 Traumatic amputation of hip and thigh
0.649 0.351 0.000
S77 Crushing injury of hip and thigh
0.649 0.351 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.649 0.351 0.000
S75 Injury of blood vessels at hip and thigh level
0.649 0.351 0.000
S74 Injury of nerves at hip and thigh level
0.649 0.351 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.649 0.351 0.000
S42.0 Fracture of clavicle
0.649 0.351 0.000
J00-J06 Acute upper respiratory infections
0.648 0.352 0.000
H46 Optic neuritis
0.648 0.352 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.648 0.352 0.000
I74 Arterial embolism and thrombosis
0.647 0.353 0.000
H26.8 Other specified cataract
0.646 0.354 0.000
H25.1 Senile nuclear cataract
0.646 0.354 0.000
I12 Hypertensive renal disease
0.646 0.354 0.000
Y43.4 Immunosuppressive agents
0.646 0.354 0.000
I88 Nonspecific lymphadenitis
0.646 0.354 0.000
Y49.2 Other and unspecified antidepressants
0.645 0.354 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.644 0.356 0.000
T46.1 Calcium-channel blockers
0.642 0.358 0.000
O86 Other puerperal infections
0.641 0.358 0.000
I45.6 Preexcitation syndrome
0.641 0.359 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.641 0.359 0.000
S48 Traumatic amputation of shoulder and upper arm
0.641 0.359 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.641 0.359 0.000
S44 Injury of nerves at shoulder and upper arm level
0.641 0.359 0.000
S41 Open wound of shoulder and upper arm
0.641 0.359 0.000
S47 Crushing injury of shoulder and upper arm
0.641 0.359 0.000
G00 Bacterial meningitis, not elsewhere classified
0.641 0.359 0.000
G36 Other acute disseminated demyelination
0.640 0.359 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.641 0.359 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.641 0.359 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.640 0.360 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.640 0.360 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.640 0.360 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.640 0.360 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.640 0.360 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.640 0.360 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.640 0.360 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.640 0.360 0.000
T36 Poisoning by systemic antibiotics
0.640 0.360 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.640 0.360 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.640 0.360 0.000
Y40.0 Penicillins
0.640 0.360 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.640 0.360 0.000
N03 Chronic nephritic syndrome
0.640 0.360 0.000
H42 Glaucoma in diseases classified elsewhere
0.638 0.362 0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.638 0.362 0.000
Q07 Other congenital malformations of nervous system
0.638 0.362 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.637 0.363 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.637 0.363 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.636 0.364 0.000
H53.1 Subjective visual disturbances
0.635 0.365 0.000
C45.9 Mesothelioma, unspecified
0.635 0.365 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.635 0.365 0.000
O82.9 Delivery by Caesarean section, unspecified
0.634 0.366 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.633 0.367 0.000
H54.0 Blindness, both eyes
0.633 0.367 0.000
J96 Respiratory failure, not elsewhere classified
0.633 0.367 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.631 0.368 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.631 0.369 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.631 0.369 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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