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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs76194019
log Bayes Factor = 13.1316
Chromosome 11   position 8,338,131  (GRCh37) Explore rs76194019 on Ensembl!
Variant rs76194019 is part of Cluster X0085

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
1.000 0.000 0.000
Chapter II Neoplasms
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
C15-C26 Malignant neoplasms of digestive organs
0.998 0.002 0.000
K30 Dyspepsia
0.998 0.002 0.000
I20-I25 Ischaemic heart diseases
0.997 0.003 0.000
I35 Nonrheumatic aortic valve disorders
0.996 0.004 0.000
I25 Chronic ischaemic heart disease
0.993 0.007 0.000
Chapter XI Diseases of the digestive system
0.993 0.007 0.000
M20-M25 Other joint disorders
0.992 0.008 0.000
I05-I09 Chronic rheumatic heart diseases
0.991 0.009 0.000
C20 Malignant neoplasm of rectum
0.990 0.010 0.000
M20 Acquired deformities of fingers and toes
0.986 0.014 0.000
K21 Gastro-oesophageal reflux disease
0.986 0.014 0.000
I08 Multiple valve diseases
0.984 0.016 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.982 0.018 0.000
I35.0 Aortic (valve) stenosis
0.982 0.018 0.000
M50-M54 Other dorsopathies
0.980 0.020 0.000
K21.9 Gastro-oesophageal reflux disease without oesophagitis
0.980 0.020 0.000
K22 Other diseases of oesophagus
0.978 0.022 0.000
J09-J18 Influenza and pneumonia
0.973 0.027 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.972 0.028 0.000
M54 Dorsalgia
0.971 0.029 0.000
M20.2 Hallux rigidus
0.968 0.032 0.000
K25 Gastric ulcer
0.963 0.037 0.000
C15 Malignant neoplasm of oesophagus
0.963 0.037 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.954 0.046 0.000
I25.2 Old myocardial infarction
0.950 0.050 0.000
M54.9 Dorsalgia, unspecified
0.949 0.051 0.000
Chapter I Certain infectious and parasitic diseases
0.944 0.056 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.938 0.062 0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.936 0.064 0.000
M54.5 Low back pain
0.932 0.068 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.931 0.069 0.000
I45 Other conduction disorders
0.929 0.071 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.927 0.073 0.000
C78.7 Secondary malignant neoplasm of liver
0.923 0.077 0.000
J30-J39 Other diseases of upper respiratory tract
0.915 0.085 0.000
C15.5 Lower third of oesophagus
0.914 0.086 0.000
J90-J94 Other diseases of pleura
0.914 0.086 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.907 0.093 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.907 0.093 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.907 0.093 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.906 0.094 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.904 0.096 0.000
M20.1 Hallux valgus (acquired)
0.900 0.100 0.000
C25 Malignant neoplasm of pancreas
0.898 0.102 0.000
K22.2 Oesophageal obstruction
0.897 0.103 0.000
I10-I15 Hypertensive diseases
0.891 0.109 0.000
I50 Heart failure
0.883 0.117 0.000
M54.56 Low back pain (Lumbar region)
0.882 0.118 0.000
J00-J06 Acute upper respiratory infections
0.880 0.120 0.000
J60-J70 Lung diseases due to external agents
0.878 0.122 0.000
M24 Other specific joint derangements
0.877 0.123 0.000
M70-M79 Other soft tissue disorders
0.871 0.129 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.870 0.130 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.867 0.133 0.000
I08.0 Disorders of both mitral and aortic valves
0.867 0.133 0.000
A30-A49 Other bacterial diseases
0.866 0.134 0.000
J18 Pneumonia, organism unspecified
0.866 0.134 0.000
M20.5 Other deformities of toe(s) (acquired)
0.865 0.135 0.000
M21 Other acquired deformities of limbs
0.864 0.136 0.000
C78.0 Secondary malignant neoplasm of lung
0.861 0.139 0.000
K22.5 Diverticulum of oesophagus, acquired
0.860 0.140 0.000
I95 Hypotension
0.856 0.144 0.000
J95-J99 Other diseases of the respiratory system
0.855 0.145 0.000
I21 Acute myocardial infarction
0.847 0.153 0.000
K29 Gastritis and duodenitis
0.846 0.154 0.000
I47 Paroxysmal tachycardia
0.840 0.160 0.000
A00-A09 Intestinal infectious diseases
0.839 0.161 0.000
K22.1 Ulcer of oesophagus
0.837 0.163 0.000
K22.4 Dyskinesia of oesophagus
0.837 0.163 0.000
C45 Mesothelioma
0.836 0.164 0.000
I10 Essential (primary) hypertension
0.834 0.166 0.000
M45-M49 Spondylopathies
0.834 0.166 0.000
I45.1 Other and unspecified right bundle-branch block
0.832 0.168 0.000
I50.9 Heart failure, unspecified
0.825 0.175 0.000
I31 Other diseases of pericardium
0.823 0.177 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.820 0.180 0.000
C15.9 Oesophagus, unspecified
0.817 0.183 0.000
I95.1 Orthostatic hypotension
0.815 0.185 0.000
I22 Subsequent myocardial infarction
0.810 0.190 0.000
B35-B49 Mycoses
0.807 0.193 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.806 0.194 0.000
I51 Complications and ill-defined descriptions of heart disease
0.802 0.198 0.000
A08 Viral and other specified intestinal infections
0.802 0.198 0.000
J93 Pneumothorax
0.798 0.202 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.798 0.202 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.797 0.203 0.000
C32 Malignant neoplasm of larynx
0.794 0.206 0.000
J02 Acute pharyngitis
0.793 0.207 0.000
I05 Rheumatic mitral valve diseases
0.792 0.208 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.792 0.208 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.791 0.209 0.000
M65-M68 Disorders of synovium and tendon
0.791 0.209 0.000
I60-I69 Cerebrovascular diseases
0.791 0.209 0.000
M80-M85 Disorders of bone density and structure
0.790 0.210 0.000
M91-M94 Chondropathies
0.789 0.210 0.000
I35.9 Aortic valve disorder, unspecified
0.789 0.211 0.000
I49 Other cardiac arrhythmias
0.785 0.215 0.000
K90-K93 Other diseases of the digestive system
0.783 0.217 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.779 0.221 0.000
J69 Pneumonitis due to solids and liquids
0.779 0.221 0.000
J33 Nasal polyp
0.779 0.221 0.000
C25.0 Head of pancreas
0.778 0.222 0.000
K27 Peptic ulcer, site unspecified
0.776 0.224 0.000
K25.3 Acute without haemorrhage or perforation
0.775 0.225 0.000
J18.9 Pneumonia, unspecified
0.775 0.225 0.000
I21.4 Acute subendocardial myocardial infarction
0.775 0.225 0.000
K22.7 Barrett's oesophagus
0.774 0.226 0.000
M20.0 Deformity of finger(s)
0.773 0.227 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.772 0.228 0.000
M72 Fibroblastic disorders
0.771 0.229 0.000
A41 Other septicaemia
0.770 0.230 0.000
K25.0 Acute with haemorrhage
0.770 0.230 0.000
I45.5 Other specified heart block
0.769 0.231 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.767 0.233 0.000
A08.4 Viral intestinal infection, unspecified
0.767 0.233 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.765 0.235 0.000
C79 Secondary malignant neoplasm of other sites
0.764 0.236 0.000
C80 Malignant neoplasm without specification of site
0.761 0.239 0.000
I25.5 Ischaemic cardiomyopathy
0.760 0.240 0.000
K35-K38 Diseases of appendix
0.760 0.240 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.759 0.241 0.000
J39 Other diseases of upper respiratory tract
0.758 0.242 0.000
C34 Malignant neoplasm of bronchus and lung
0.758 0.242 0.000
I36 Nonrheumatic tricuspid valve disorders
0.756 0.244 0.000
I44 Atrioventricular and left bundle-branch block
0.754 0.245 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.754 0.246 0.000
J32 Chronic sinusitis
0.750 0.250 0.000
I50.0 Congestive heart failure
0.749 0.251 0.000
J98 Other respiratory disorders
0.749 0.251 0.000
C25.9 Pancreas, unspecified
0.744 0.255 0.000
M60-M63 Disorders of muscles
0.744 0.256 0.000
M40-M43 Deforming dorsopathies
0.744 0.256 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.744 0.256 0.000
Chapter VI Diseases of the nervous system
0.743 0.257 0.000
C78.2 Secondary malignant neoplasm of pleura
0.742 0.258 0.000
Chapter XXII Codes for special purposes
0.740 0.260 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.738 0.262 0.000
M54.2 Cervicalgia
0.738 0.262 0.000
I25.3 Aneurysm of heart
0.737 0.263 0.000
I30 Acute pericarditis
0.733 0.266 0.000
J02.9 Acute pharyngitis, unspecified
0.731 0.269 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.730 0.270 0.000
M00-M03 Infectious arthropathies
0.729 0.271 0.000
C45.9 Mesothelioma, unspecified
0.728 0.272 0.000
J91 Pleural effusion in conditions classified elsewhere
0.728 0.272 0.000
J92 Pleural plaque
0.728 0.272 0.000
K29.5 Chronic gastritis, unspecified
0.728 0.272 0.000
C45.0 Mesothelioma of pleura
0.728 0.272 0.000
C18 Malignant neoplasm of colon
0.727 0.273 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.724 0.276 0.000
I38 Endocarditis, valve unspecified
0.721 0.279 0.000
I24 Other acute ischaemic heart diseases
0.721 0.279 0.000
M24.2 Disorder of ligament
0.720 0.280 0.000
M25 Other joint disorders, not elsewhere classified
0.719 0.281 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.719 0.281 0.000
I31.9 Disease of pericardium, unspecified
0.719 0.281 0.000
I35.1 Aortic (valve) insufficiency
0.718 0.281 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
K28 Gastrojejunal ulcer
0.717 0.283 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.717 0.283 0.000
B99-B99 Other infectious diseases
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.716 0.284 0.000
C21 Malignant neoplasm of anus and anal canal
0.716 0.284 0.000
C17 Malignant neoplasm of small intestine
0.716 0.284 0.000
C23 Malignant neoplasm of gallbladder
0.716 0.284 0.000
K29.4 Chronic atrophic gastritis
0.715 0.284 0.000
I23 Certain current complications following acute myocardial infarction
0.715 0.285 0.000
I35.8 Other aortic valve disorders
0.714 0.286 0.000
M21.0 Valgus deformity, not elsewhere classified
0.714 0.286 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.714 0.286 0.000
M50 Cervical disk disorders
0.713 0.287 0.000
I47.1 Supraventricular tachycardia
0.713 0.287 0.000
J35 Chronic diseases of tonsils and adenoids
0.712 0.288 0.000
I25.6 Silent myocardial ischaemia
0.712 0.288 0.000
I25.4 Coronary artery aneurysm
0.712 0.288 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.712 0.288 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.711 0.289 0.000
M33 Dermatopolymyositis
0.711 0.289 0.000
M32 Systemic lupus erythematosus
0.711 0.289 0.000
M30 Polyarteritis nodosa and related conditions
0.711 0.289 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.711 0.289 0.000
M24.0 Loose body in joint
0.711 0.289 0.000
I09 Other rheumatic heart diseases
0.711 0.289 0.000
I06 Rheumatic aortic valve diseases
0.711 0.289 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.709 0.291 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.709 0.291 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.709 0.291 0.000
J69.0 Pneumonitis due to food and vomit
0.708 0.292 0.000
K22.9 Disease of oesophagus, unspecified
0.708 0.292 0.000
M21.2 Flexion deformity
0.707 0.293 0.000
M20.3 Other deformity of hallux (acquired)
0.707 0.293 0.000
J11 Influenza, virus not identified
0.706 0.294 0.000
I08.9 Multiple valve disease, unspecified
0.705 0.294 0.000
I08.8 Other multiple valve diseases
0.705 0.294 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.705 0.294 0.000
M48 Other spondylopathies
0.704 0.296 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.704 0.296 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.704 0.296 0.000
J31.0 Chronic rhinitis
0.704 0.296 0.000
J00 Acute nasopharyngitis [common cold]
0.703 0.297 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.703 0.297 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.702 0.298 0.000
K22.3 Perforation of oesophagus
0.701 0.298 0.000
C16 Malignant neoplasm of stomach
0.701 0.299 0.000
I45.2 Bifascicular block
0.701 0.299 0.000
M54.6 Pain in thoracic spine
0.701 0.299 0.000
M86-M90 Other osteopathies
0.700 0.300 0.000
K29.6 Other gastritis
0.700 0.300 0.000
J10 Influenza due to identified influenza virus
0.699 0.301 0.000
I25.1 Atherosclerotic heart disease
0.698 0.302 0.000
J17 Pneumonia in diseases classified elsewhere
0.697 0.302 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.697 0.302 0.000
J12 Viral pneumonia, not elsewhere classified
0.697 0.302 0.000
J09 Influenza due to certain identified influenza virus
0.697 0.302 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.697 0.303 0.000
J14 Pneumonia due to Haemophilus influenzae
0.697 0.303 0.000
M31 Other necrotising vasculopathies
0.697 0.303 0.000
M54.8 Other dorsalgia
0.696 0.303 0.000
M54.0 Panniculitis affecting regions of neck and back
0.696 0.303 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.695 0.305 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.695 0.305 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.694 0.306 0.000
K29.0 Acute haemorrhagic gastritis
0.694 0.306 0.000
C32.1 Supraglottis
0.694 0.306 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.694 0.306 0.000
M15-M19 Arthrosis
0.693 0.307 0.000
M34 Systemic sclerosis
0.691 0.309 0.000
J93.9 Pneumothorax, unspecified
0.691 0.309 0.000
K25.6 Chronic or unspecified with both haemorrhage and perforation
0.690 0.310 0.000
K25.5 Chronic or unspecified with perforation
0.690 0.310 0.000
K25.2 Acute with both haemorrhage and perforation
0.690 0.310 0.000
K25.1 Acute with perforation
0.690 0.310 0.000
C15.8 Overlapping lesion of oesophagus
0.690 0.310 0.000
C15.4 Middle third of oesophagus
0.690 0.310 0.000
C15.3 Upper third of oesophagus
0.690 0.310 0.000
C15.2 Abdominal part of oesophagus
0.690 0.310 0.000
C15.1 Thoracic part of oesophagus
0.690 0.310 0.000
C15.0 Cervical part of oesophagus
0.690 0.310 0.000
K20 Oesophagitis
0.690 0.310 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.688 0.312 0.000
M54.4 Lumbago with sciatica
0.686 0.314 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.685 0.315 0.000
A40 Streptococcal septicaemia
0.684 0.315 0.000
K29.2 Alcoholic gastritis
0.683 0.317 0.000
A41.8 Other specified septicaemia
0.683 0.317 0.000
J30 Vasomotor and allergic rhinitis
0.682 0.318 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.681 0.319 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.680 0.320 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.680 0.320 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.680 0.320 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.680 0.320 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.680 0.320 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.680 0.320 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.680 0.320 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.680 0.320 0.000
I95.2 Hypotension due to drugs
0.679 0.320 0.000
K22.8 Other specified diseases of oesophagus
0.679 0.321 0.000
Q50-Q56 Congenital malformations of genital organs
0.679 0.321 0.000
J94 Other pleural conditions
0.678 0.322 0.000
J81 Pulmonary oedema
0.678 0.322 0.000
K50-K52 Noninfective enteritis and colitis
0.678 0.322 0.000
M54.57 Low back pain (Lumbosacral region)
0.677 0.323 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.677 0.323 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.677 0.323 0.000
B65-B83 Helminthiases
0.677 0.323 0.000
B50-B64 Protozoal diseases
0.677 0.323 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.677 0.323 0.000
A80-A89 Viral infections of the central nervous system
0.677 0.323 0.000
A75-A79 Rickettsioses
0.677 0.323 0.000
A70-A74 Other diseases caused by chlamydiae
0.677 0.323 0.000
A65-A69 Other spirochaetal diseases
0.677 0.323 0.000
A20-A28 Certain zoonotic bacterial diseases
0.677 0.323 0.000
A15-A19 Tuberculosis
0.677 0.323 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.676 0.324 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.676 0.324 0.000
I07 Rheumatic tricuspid valve diseases
0.675 0.325 0.000
I63 Cerebral infarction
0.675 0.325 0.000
I49.4 Other and unspecified premature depolarisation
0.675 0.325 0.000
M21.3 Wrist or foot drop (acquired)
0.675 0.325 0.000
M45 Ankylosing spondylitis
0.673 0.327 0.000
I45.6 Preexcitation syndrome
0.672 0.328 0.000
A48 Other bacterial diseases, not elsewhere classified
0.672 0.328 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.670 0.330 0.000
M53 Other dorsopathies, not elsewhere classified
0.670 0.330 0.000
M54.55 Low back pain (Thoracolumbar region)
0.668 0.331 0.000
M54.54 Low back pain-Thoracic
0.668 0.331 0.000
M54.53 Low back pain-Cervicothoracic
0.668 0.331 0.000
M54.52 Low back pain-Cervical
0.668 0.331 0.000
M54.51 Low back pain-Occipit-atl-axl
0.668 0.331 0.000
M54.50 Low back pain (Multiple sites in spine)
0.668 0.331 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.668 0.332 0.000
I45.9 Conduction disorder, unspecified
0.666 0.334 0.000
I45.8 Other specified conduction disorders
0.666 0.334 0.000
I45.4 Nonspecific intraventricular block
0.666 0.334 0.000
I45.3 Trifascicular block
0.666 0.334 0.000
I45.0 Right fascicular block
0.666 0.334 0.000
J37 Chronic laryngitis and laryngotracheitis
0.666 0.334 0.000
J98.4 Other disorders of lung
0.666 0.334 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.663 0.337 0.000
D80-D89 Certain disorders involving the immune mechanism
0.663 0.337 0.000
M84 Disorders of continuity of bone
0.662 0.337 0.000
A46 Erysipelas
0.662 0.338 0.000
I51.6 Cardiovascular disease, unspecified
0.661 0.339 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.659 0.341 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.659 0.341 0.000
K92 Other diseases of digestive system
0.657 0.343 0.000
B37 Candidiasis
0.656 0.344 0.000
J18.0 Bronchopneumonia, unspecified
0.655 0.345 0.000
I46 Cardiac arrest
0.653 0.347 0.000
J39.2 Other diseases of pharynx
0.653 0.347 0.000
B44 Aspergillosis
0.651 0.349 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.650 0.349 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.650 0.349 0.000
C31 Malignant neoplasm of accessory sinuses
0.650 0.349 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.650 0.349 0.000
C37 Malignant neoplasm of thymus
0.650 0.349 0.000
C33 Malignant neoplasm of trachea
0.650 0.349 0.000
I49.9 Cardiac arrhythmia, unspecified
0.650 0.350 0.000
M25.3 Other instability of joint
0.650 0.350 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.650 0.350 0.000
I99 Other and unspecified disorders of circulatory system
0.650 0.350 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.650 0.350 0.000
I44.2 Atrioventricular block, complete
0.650 0.350 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.649 0.351 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.648 0.352 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.648 0.352 0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.648 0.352 0.000
C46 Kaposi's sarcoma
0.648 0.352 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.646 0.354 0.000
M75 Shoulder lesions
0.646 0.354 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.646 0.354 0.000
Q60-Q64 Congenital malformations of the urinary system
0.646 0.354 0.000
K22.0 Achalasia of cardia
0.645 0.355 0.000
C25.8 Overlapping lesion of pancreas
0.644 0.356 0.000
C25.7 Other parts of pancreas
0.644 0.356 0.000
C25.4 Endocrine pancreas
0.644 0.356 0.000
C25.3 Pancreatic duct
0.644 0.356 0.000
C25.2 Tail of pancreas
0.644 0.356 0.000
C25.1 Body of pancreas
0.644 0.356 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.643 0.356 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.641 0.359 0.000
I87 Other disorders of veins
0.641 0.359 0.000
B15-B19 Viral hepatitis
0.640 0.360 0.000
C79.2 Secondary malignant neoplasm of skin
0.639 0.361 0.000
I69 Sequelae of cerebrovascular disease
0.639 0.361 0.000
I15 Secondary hypertension
0.639 0.361 0.000
I13 Hypertensive heart and renal disease
0.639 0.361 0.000
I11 Hypertensive heart disease
0.639 0.361 0.000
C34.1 Upper lobe, bronchus or lung
0.638 0.362 0.000
D68 Other coagulation defects
0.637 0.363 0.000
C60-C63 Malignant neoplasms of male genital organs
0.637 0.363 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.635 0.365 0.000
I22.8 Subsequent myocardial infarction of other sites
0.635 0.365 0.000
M93 Other osteochondropathies
0.635 0.365 0.000
M24.1 Other articular cartilage disorders
0.635 0.365 0.000
I33 Acute and subacute endocarditis
0.633 0.367 0.000
J33.0 Polyp of nasal cavity
0.632 0.368 0.000
J04 Acute laryngitis and tracheitis
0.631 0.369 0.000
J01 Acute sinusitis
0.631 0.369 0.000
M77 Other enthesopathies
0.630 0.370 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.630 0.370 0.000
J70 Respiratory conditions due to other external agents
0.629 0.371 0.000
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.629 0.371 0.000
J67 Hypersensitivity pneumonitis due to organic dust
0.629 0.371 0.000
J66 Airway disease due to specific organic dust
0.629 0.371 0.000
J63 Pneumoconiosis due to other inorganic dusts
0.629 0.371 0.000
J62 Pneumoconiosis due to dust containing silica
0.629 0.371 0.000
J65 Pneumoconiosis associated with tuberculosis
0.629 0.371 0.000
J64 Unspecified pneumoconiosis
0.629 0.371 0.000
J60 Coalworker's pneumoconiosis
0.629 0.371 0.000
M71 Other bursopathies
0.629 0.371 0.000
M24.9 Joint derangement, unspecified
0.629 0.371 0.000
M24.7 Protrusio acetabuli
0.629 0.371 0.000
M24.6 Ankylosis of joint
0.629 0.371 0.000
M24.5 Contracture of joint
0.629 0.371 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.629 0.371 0.000
J90 Pleural effusion, not elsewhere classified
0.629 0.371 0.000
A08.1 Acute gastro-enteropathy due to Norwalk agent
0.628 0.372 0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.628 0.372 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.627 0.373 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.627 0.373 0.000
M50.1 Cervical disk disorder with radiculopathy
0.625 0.375 0.000
C34.2 Middle lobe, bronchus or lung
0.625 0.375 0.000
M76 Enthesopathies of lower limb, excluding foot
0.625 0.375 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.625 0.375 0.000
J18.1 Lobar pneumonia, unspecified
0.624 0.376 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.624 0.376 0.000
J93.1 Other spontaneous pneumothorax
0.623 0.376 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.623 0.377 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.622 0.378 0.000
Q80-Q89 Other congenital malformations
0.622 0.378 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.622 0.378 0.000
Q35-Q37 Cleft lip and cleft palate
0.622 0.378 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.622 0.378 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.622 0.378 0.000
C71 Malignant neoplasm of brain
0.622 0.378 0.000
A44 Bartonellosis
0.621 0.379 0.000
A43 Nocardiosis
0.621 0.379 0.000
A42 Actinomycosis
0.621 0.379 0.000
A39 Meningococcal infection
0.621 0.379 0.000
A37 Whooping cough
0.621 0.379 0.000
A36 Diphtheria
0.621 0.379 0.000
A32 Listeriosis
0.621 0.379 0.000
A31 Infection due to other mycobacteria
0.621 0.379 0.000
A30 Leprosy [Hansen's disease]
0.621 0.379 0.000
A38 Scarlet fever
0.621 0.379 0.000
A35 Other tetanus
0.621 0.379 0.000
A34 Obstetrical tetanus
0.621 0.379 0.000
A33 Tetanus neonatorum
0.621 0.379 0.000
J18.8 Other pneumonia, organism unspecified
0.621 0.379 0.000
J18.2 Hypostatic pneumonia, unspecified
0.621 0.379 0.000
I05.2 Mitral stenosis with insufficiency
0.620 0.380 0.000
M21.9 Acquired deformity of limb, unspecified
0.619 0.381 0.000
M21.8 Other specified acquired deformities of limbs
0.619 0.381 0.000
M21.7 Unequal limb length (acquired)
0.619 0.381 0.000
M21.6 Other acquired deformities of ankle and foot
0.619 0.381 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.619 0.381 0.000
M21.4 Flat foot [pes planus] (acquired)
0.619 0.381 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.619 0.381 0.000
I42 Cardiomyopathy
0.619 0.381 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.619 0.381 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.618 0.381 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.617 0.383 0.000
M19 Other arthrosis
0.617 0.383 0.000
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.616 0.384 0.000
Q00-Q07 Congenital malformations of the nervous system
0.615 0.384 0.000
M54.59 Low back pain (Site unspecified)
0.615 0.385 0.000
K25.4 Chronic or unspecified with haemorrhage
0.615 0.385 0.000
C18.3 Hepatic flexure
0.614 0.386 0.000
O85-O92 Complications predominantly related to the puerperium
0.614 0.386 0.000
I95.8 Other hypotension
0.613 0.386 0.000
I95.0 Idiopathic hypotension
0.613 0.386 0.000
J33.8 Other polyp of sinus
0.613 0.386 0.000
J96 Respiratory failure, not elsewhere classified
0.613 0.387 0.000
J32.9 Chronic sinusitis, unspecified
0.613 0.387 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.612 0.387 0.000
C32.9 Larynx, unspecified
0.612 0.388 0.000
M48.0 Spinal stenosis
0.612 0.388 0.000
I05.9 Mitral valve disease, unspecified
0.608 0.392 0.000
M24.24 Disorder of ligament (Hand)
0.607 0.392 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.607 0.392 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.607 0.393 0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)
0.607 0.393 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.607 0.393 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.607 0.393 0.000
K29.9 Gastroduodenitis, unspecified
0.606 0.394 0.000
I81 Portal vein thrombosis
0.606 0.394 0.000
M65 Synovitis and tenosynovitis
0.606 0.394 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.605 0.395 0.000
I80 Phlebitis and thrombophlebitis
0.602 0.398 0.000
I47.0 Reentry ventricular arrhythmia
0.602 0.398 0.000
A07 Other protozoal intestinal diseases
0.602 0.398 0.000
A06 Amoebiasis
0.602 0.398 0.000
A05 Other bacterial foodborne intoxications
0.602 0.398 0.000
A03 Shigellosis
0.602 0.398 0.000
A02 Other Salmonella infections
0.602 0.398 0.000
A01 Typhoid and paratyphoid fevers
0.602 0.398 0.000
A00 Cholera
0.602 0.398 0.000
I51.7 Cardiomegaly
0.600 0.400 0.000
C45.7 Mesothelioma of other sites
0.599 0.401 0.000
C45.2 Mesothelioma of pericardium
0.599 0.401 0.000
C45.1 Mesothelioma of peritoneum
0.599 0.401 0.000
M66 Spontaneous rupture of synovium and tendon
0.599 0.401 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.599 0.401 0.000
M49 Spondylopathies in diseases classified elsewhere
0.598 0.402 0.000
G40-G47 Episodic and paroxysmal disorders
0.597 0.403 0.000
I27 Other pulmonary heart diseases
0.597 0.403 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.596 0.404 0.000
M54.3 Sciatica
0.596 0.404 0.000
I21.9 Acute myocardial infarction, unspecified
0.596 0.404 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.596 0.404 0.000
M21.24 Flexion deformity (Hand)
0.595 0.405 0.000
I63.9 Cerebral infarction, unspecified
0.595 0.405 0.000
I20 Angina pectoris
0.595 0.405 0.000
I86 Varicose veins of other sites
0.593 0.407 0.000
J92.0 Pleural plaque with presence of asbestos
0.593 0.407 0.000
M24.02 Loose body in joint (Upper arm)
0.592 0.408 0.000
J32.0 Chronic maxillary sinusitis
0.592 0.408 0.000
B00 Herpesviral [herpes simplex] infections
0.591 0.409 0.000
I44.0 Atrioventricular block, first degree
0.591 0.409 0.000
I60 Subarachnoid haemorrhage
0.590 0.410 0.000
B35 Dermatophytosis
0.590 0.410 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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