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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs76335573
log Bayes Factor = 12.4927
Chromosome 1   position 107,687,605  (GRCh37) Explore rs76335573 on Ensembl!
Variant rs76335573 is part of Cluster X0102

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
0.999 0.001 0.000
Chapter XX External causes of morbidity and mortality
0.999 0.001 0.000
M05-M14 Inflammatory polyarthropathies
0.998 0.002 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.994 0.006 0.000
I34 Nonrheumatic mitral valve disorders
0.994 0.006 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.992 0.008 0.000
M13 Other arthritis
0.990 0.010 0.000
I50 Heart failure
0.990 0.010 0.000
N72 Inflammatory disease of cervix uteri
0.989 0.011 0.000
W00-W19 Falls
0.986 0.014 0.000
M13.9 Arthritis, unspecified
0.984 0.016 0.000
Chapter XI Diseases of the digestive system
0.980 0.020 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.978 0.022 0.000
N10-N16 Renal tubulo-interstitial diseases
0.978 0.022 0.000
I38 Endocarditis, valve unspecified
0.976 0.024 0.000
N13 Obstructive and reflux uropathy
0.975 0.025 0.000
K50-K52 Noninfective enteritis and colitis
0.968 0.032 0.000
M45-M49 Spondylopathies
0.968 0.032 0.000
K51 Ulcerative colitis
0.966 0.034 0.000
W19 Unspecified fall
0.966 0.034 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.964 0.036 0.000
I05-I09 Chronic rheumatic heart diseases
0.962 0.038 0.000
I34.0 Mitral (valve) insufficiency
0.962 0.038 0.000
M15-M19 Arthrosis
0.962 0.038 0.000
M50-M54 Other dorsopathies
0.961 0.039 0.000
N25-N29 Other disorders of kidney and ureter
0.960 0.040 0.000
M54 Dorsalgia
0.952 0.048 0.000
I45 Other conduction disorders
0.951 0.049 0.000
M19 Other arthrosis
0.949 0.051 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.948 0.052 0.000
M54.5 Low back pain
0.943 0.057 0.000
W19.2 School, other institution and public administrative area
0.940 0.060 0.000
K51.2 Ulcerative (chronic) proctitis
0.940 0.060 0.000
M06 Other rheumatoid arthritis
0.937 0.063 0.000
O60-O75 Complications of labour and delivery
0.936 0.064 0.000
I08 Multiple valve diseases
0.933 0.067 0.000
M54.59 Low back pain (Site unspecified)
0.931 0.069 0.000
N13.3 Other and unspecified hydronephrosis
0.929 0.071 0.000
M19.9 Arthrosis, unspecified
0.927 0.073 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.925 0.075 0.000
I50.0 Congestive heart failure
0.924 0.076 0.000
I34.1 Mitral (valve) prolapse
0.923 0.077 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.915 0.085 0.000
K08 Other disorders of teeth and supporting structures
0.914 0.086 0.000
M06.9 Rheumatoid arthritis, unspecified
0.911 0.089 0.000
N00-N08 Glomerular diseases
0.910 0.090 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.909 0.091 0.000
N17-N19 Renal failure
0.908 0.092 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.908 0.092 0.000
I50.9 Heart failure, unspecified
0.907 0.093 0.000
M86-M90 Other osteopathies
0.903 0.097 0.000
N28.8 Other specified disorders of kidney and ureter
0.901 0.099 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.899 0.101 0.000
K12 Stomatitis and related lesions
0.897 0.103 0.000
Y40 Systemic antibiotics
0.892 0.108 0.000
M80-M85 Disorders of bone density and structure
0.887 0.113 0.000
I50.1 Left ventricular failure
0.884 0.116 0.000
K90-K93 Other diseases of the digestive system
0.883 0.117 0.000
O69.1 Labour and delivery complicated by cord around neck, with compression
0.879 0.121 0.000
K51.8 Other ulcerative colitis
0.878 0.122 0.000
M45 Ankylosing spondylitis
0.876 0.124 0.000
N17 Acute renal failure
0.876 0.124 0.000
Chapter I Certain infectious and parasitic diseases
0.874 0.126 0.000
I45.1 Other and unspecified right bundle-branch block
0.873 0.127 0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease
0.870 0.130 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.868 0.132 0.000
I08.0 Disorders of both mitral and aortic valves
0.865 0.135 0.000
I33 Acute and subacute endocarditis
0.865 0.135 0.000
B95-B98 Bacterial, viral and other infectious agents
0.862 0.138 0.000
K51.4 Pseudopolyposis of colon
0.862 0.138 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.860 0.140 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.857 0.143 0.000
I45.5 Other specified heart block
0.856 0.144 0.000
N17.9 Acute renal failure, unspecified
0.854 0.146 0.000
M19.0 Primary arthrosis of other joints
0.854 0.146 0.000
Y52 Agents primarily affecting the cardiovascular system
0.852 0.148 0.000
M70-M79 Other soft tissue disorders
0.851 0.149 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.851 0.149 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.850 0.150 0.000
M47 Spondylosis
0.848 0.152 0.000
K40-K46 Hernia
0.847 0.153 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.845 0.155 0.000
K12.1 Other forms of stomatitis
0.844 0.156 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.844 0.156 0.000
K08.8 Other specified disorders of teeth and supporting structures
0.844 0.156 0.000
K43 Ventral hernia
0.843 0.157 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.841 0.159 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.841 0.159 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.838 0.162 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.838 0.162 0.000
M46 Other inflammatory spondylopathies
0.837 0.163 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.834 0.166 0.000
K43.9 Ventral hernia without obstruction or gangrene
0.832 0.168 0.000
N76 Other inflammation of vagina and vulva
0.831 0.169 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.830 0.170 0.000
M20-M25 Other joint disorders
0.829 0.171 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.827 0.172 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.827 0.173 0.000
W18 Other fall on same level
0.827 0.173 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.826 0.174 0.000
I31 Other diseases of pericardium
0.825 0.175 0.000
N02 Recurrent and persistent haematuria
0.824 0.176 0.000
M91-M94 Chondropathies
0.822 0.178 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.822 0.178 0.000
M54.56 Low back pain (Lumbar region)
0.822 0.178 0.000
N13.6 Pyonephrosis
0.821 0.179 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.821 0.179 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.820 0.180 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.820 0.180 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.817 0.183 0.000
K10 Other diseases of jaws
0.817 0.183 0.000
W06 Fall involving bed
0.816 0.184 0.000
W07 Fall involving chair
0.816 0.184 0.000
Y44 Agents primarily affecting blood constituents
0.812 0.188 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.810 0.190 0.000
I60-I69 Cerebrovascular diseases
0.809 0.191 0.000
N05 Unspecified nephritic syndrome
0.807 0.193 0.000
W19.1 Residential institution
0.806 0.194 0.000
K91.3 Postoperative intestinal obstruction
0.803 0.197 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.797 0.203 0.000
M54.3 Sciatica
0.793 0.207 0.000
M19.04 Primary arthrosis of other joints (Hand)
0.793 0.207 0.000
Chapter VIII Diseases of the ear and mastoid process
0.793 0.207 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.789 0.211 0.000
Chapter XXI Factors influencing health status and contact with health services
0.789 0.211 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.789 0.211 0.000
N70 Salpingitis and oophoritis
0.788 0.212 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.787 0.213 0.000
O85-O92 Complications predominantly related to the puerperium
0.786 0.213 0.000
I60 Subarachnoid haemorrhage
0.786 0.214 0.000
M13.98 Arthritis, unspecified (Other)
0.781 0.219 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.781 0.219 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.781 0.219 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.780 0.220 0.000
Z36 Antenatal screening
0.780 0.220 0.000
M53 Other dorsopathies, not elsewhere classified
0.779 0.221 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.779 0.221 0.000
M54.4 Lumbago with sciatica
0.775 0.225 0.000
Z35 Supervision of high-risk pregnancy
0.773 0.227 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.769 0.231 0.000
I33.0 Acute and subacute infective endocarditis
0.769 0.231 0.000
K43.0 Ventral hernia with obstruction, without gangrene
0.765 0.235 0.000
N99-N99 Other disorders of the genitourinary system
0.765 0.235 0.000
M89 Other disorders of bone
0.765 0.235 0.000
K14 Diseases of tongue
0.765 0.235 0.000
M40-M43 Deforming dorsopathies
0.764 0.236 0.000
I46 Cardiac arrest
0.762 0.238 0.000
O71 Other obstetric trauma
0.762 0.238 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.762 0.238 0.000
M21 Other acquired deformities of limbs
0.760 0.240 0.000
O69.8 Labour and delivery complicated by other cord complications
0.758 0.242 0.000
X60-X84 Intentional self-harm
0.758 0.242 0.000
I08.8 Other multiple valve diseases
0.756 0.244 0.000
M05 Seropositive rheumatoid arthritis
0.754 0.246 0.000
Y00-Y09 Assault
0.754 0.246 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.753 0.247 0.000
M54.8 Other dorsalgia
0.751 0.249 0.000
N02.9 Unspecified
0.751 0.249 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.750 0.250 0.000
N13.4 Hydroureter
0.750 0.250 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.749 0.251 0.000
I51 Complications and ill-defined descriptions of heart disease
0.748 0.252 0.000
W19.9 Unspecified place
0.747 0.253 0.000
O42 Premature rupture of membranes
0.746 0.254 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.744 0.255 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.744 0.255 0.000
I27 Other pulmonary heart diseases
0.744 0.256 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.744 0.256 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.743 0.257 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.743 0.257 0.000
O72 Postpartum haemorrhage
0.743 0.257 0.000
M65-M68 Disorders of synovium and tendon
0.742 0.258 0.000
M13.0 Polyarthritis, unspecified
0.741 0.259 0.000
K00 Disorders of tooth development and eruption
0.740 0.260 0.000
M60-M63 Disorders of muscles
0.739 0.261 0.000
V80-V89 Other land transport accidents
0.739 0.261 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.739 0.261 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.739 0.261 0.000
N26 Unspecified contracted kidney
0.738 0.262 0.000
I37 Pulmonary valve disorders
0.737 0.263 0.000
Chapter V Mental and behavioural disorders
0.737 0.263 0.000
Y40.5 Aminoglycosides
0.736 0.264 0.000
I05 Rheumatic mitral valve diseases
0.736 0.264 0.000
I30 Acute pericarditis
0.735 0.265 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.734 0.266 0.000
W19.4 Street and highway
0.734 0.266 0.000
M86 Osteomyelitis
0.734 0.266 0.000
O69.2 Labour and delivery complicated by other cord entanglement
0.733 0.267 0.000
Y85 Sequelae of transport accidents
0.733 0.267 0.000
K51.5 Mucosal proctocolitis
0.733 0.267 0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods
0.732 0.268 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.731 0.269 0.000
M19.94 Arthrosis, unspecified (Hand)
0.731 0.269 0.000
Z36.9 Antenatal screening, unspecified
0.730 0.270 0.000
M47.9 Spondylosis, unspecified
0.729 0.271 0.000
N11 Chronic tubulo-interstitial nephritis
0.727 0.273 0.000
M07 Psoriatic and enteropathic arthropathies
0.726 0.274 0.000
Z35.5 Supervision of elderly primigravida
0.726 0.274 0.000
Y40.1 Cefalosporins and other -lactam antibiotics
0.725 0.275 0.000
N05.2 Diffuse membranous glomerulonephritis
0.724 0.276 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.724 0.276 0.000
I62 Other nontraumatic intracranial haemorrhage
0.724 0.276 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.723 0.277 0.000
M82 Osteoporosis in diseases classified elsewhere
0.722 0.278 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.722 0.278 0.000
M14 Arthropathies in other diseases classified elsewhere
0.721 0.279 0.000
Y40.8 Other systemic antibiotics
0.721 0.279 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.720 0.280 0.000
W18.3 Sports and athletics area
0.720 0.280 0.000
Chapter XXII Codes for special purposes
0.719 0.281 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.718 0.282 0.000
H80-H83 Diseases of inner ear
0.717 0.283 0.000
X20-X29 Contact with venomous animals and plants
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.716 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.716 0.284 0.000
Y10-Y34 Event of undetermined intent
0.716 0.284 0.000
X85-X99 Assault
0.716 0.284 0.000
X30-X39 Exposure to forces of nature
0.716 0.284 0.000
X10-X19 Contact with heat and hot substances
0.716 0.284 0.000
X00-X09 Exposure to smoke, fire and flames
0.716 0.284 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.716 0.284 0.000
W75-W84 Other accidental threats to breathing
0.716 0.284 0.000
W65-W74 Accidental drowning and submersion
0.716 0.284 0.000
W50-W64 Exposure to animate mechanical forces
0.716 0.284 0.000
V98-V99 Other and unspecified transport accidents
0.716 0.284 0.000
V95-V97 Air and space transport accidents
0.716 0.284 0.000
V90-V94 Water transport accidents
0.716 0.284 0.000
V70-V79 Bus occupant injured in transport accident
0.716 0.284 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.716 0.284 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.716 0.284 0.000
V40-V49 Car occupant injured in transport accident
0.716 0.284 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.716 0.284 0.000
V01-V09 Pedestrian injured in transport accident
0.716 0.284 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.716 0.284 0.000
M12 Other specific arthropathies
0.715 0.285 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.715 0.285 0.000
M08 Juvenile arthritis
0.715 0.285 0.000
M00-M03 Infectious arthropathies
0.713 0.287 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.713 0.287 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.712 0.287 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.712 0.287 0.000
I45.8 Other specified conduction disorders
0.712 0.288 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.712 0.288 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.712 0.288 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.711 0.289 0.000
Y59 Other and unspecified vaccines and biological substances
0.711 0.289 0.000
Y58 Bacterial vaccines
0.711 0.289 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.711 0.289 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.711 0.289 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.711 0.289 0.000
Y48 Anaesthetics and therapeutic gases
0.711 0.289 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.711 0.289 0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.711 0.289 0.000
M24 Other specific joint derangements
0.711 0.289 0.000
V10-V19 Pedal cyclist injured in transport accident
0.711 0.289 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.711 0.289 0.000
M84 Disorders of continuity of bone
0.710 0.290 0.000
M13.8 Other specified arthritis
0.710 0.290 0.000
M13.1 Monoarthritis, not elsewhere classified
0.710 0.290 0.000
N75 Diseases of Bartholin's gland
0.710 0.290 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.709 0.290 0.000
M75 Shoulder lesions
0.710 0.290 0.000
M80 Osteoporosis with pathological fracture
0.708 0.292 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.707 0.293 0.000
W17 Other fall from one level to another
0.707 0.293 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.707 0.293 0.000
W15 Fall from cliff
0.707 0.293 0.000
W14 Fall from tree
0.707 0.293 0.000
W12 Fall on and from scaffolding
0.707 0.293 0.000
W11 Fall on and from ladder
0.707 0.293 0.000
W09 Fall involving playground equipment
0.707 0.293 0.000
W05 Fall involving wheelchair
0.707 0.293 0.000
W04 Fall while being carried or supported by other persons
0.707 0.293 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.707 0.293 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.707 0.293 0.000
W00 Fall on same level involving ice and snow
0.707 0.293 0.000
K12.0 Recurrent oral aphthae
0.706 0.294 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.706 0.294 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.706 0.294 0.000
M13.93 Arthritis, unspecified (Forearm)
0.705 0.295 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.704 0.296 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.704 0.296 0.000
X50-X57 Overexertion, travel and privation
0.703 0.297 0.000
M13.94 Arthritis, unspecified (Hand)
0.703 0.297 0.000
T93 Sequelae of injuries of lower limb
0.703 0.297 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.701 0.299 0.000
N15 Other renal tubulo-interstitial diseases
0.701 0.299 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.701 0.299 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.700 0.300 0.000
N28.0 Ischaemia and infarction of kidney
0.700 0.300 0.000
I31.9 Disease of pericardium, unspecified
0.699 0.300 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.699 0.301 0.000
M54.57 Low back pain (Lumbosacral region)
0.699 0.301 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.698 0.302 0.000
I36 Nonrheumatic tricuspid valve disorders
0.698 0.302 0.000
M06.3 Rheumatoid nodule
0.696 0.304 0.000
M94 Other disorders of cartilage
0.696 0.304 0.000
M19.98 Arthrosis, unspecified (Other)
0.695 0.305 0.000
M49 Spondylopathies in diseases classified elsewhere
0.694 0.306 0.000
D75 Other diseases of blood and blood-forming organs
0.694 0.306 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.693 0.307 0.000
W19.8 Other specified place
0.692 0.307 0.000
W19.5 Trade and service area
0.692 0.307 0.000
W19.0 Home
0.692 0.307 0.000
W19.7 Farm
0.692 0.307 0.000
W19.6 Industrial and construction area
0.692 0.307 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.691 0.309 0.000
I09 Other rheumatic heart diseases
0.690 0.310 0.000
I06 Rheumatic aortic valve diseases
0.690 0.310 0.000
K51.9 Ulcerative colitis, unspecified
0.690 0.310 0.000
M15 Polyarthrosis
0.689 0.311 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.689 0.311 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.688 0.312 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.688 0.312 0.000
N27 Small kidney of unknown cause
0.688 0.312 0.000
N25 Disorders resulting from impaired renal tubular function
0.688 0.312 0.000
Y41.0 Sulphonamides
0.688 0.312 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.687 0.313 0.000
M11 Other crystal arthropathies
0.687 0.313 0.000
N18 Chronic renal failure
0.687 0.313 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.684 0.316 0.000
Z35.8 Supervision of other high-risk pregnancies
0.684 0.316 0.000
M10 Gout
0.683 0.317 0.000
K10.2 Inflammatory conditions of jaws
0.683 0.317 0.000
Y44.2 Anticoagulants
0.683 0.317 0.000
M54.0 Panniculitis affecting regions of neck and back
0.682 0.318 0.000
I45.4 Nonspecific intraventricular block
0.682 0.318 0.000
I45.3 Trifascicular block
0.682 0.318 0.000
I45.2 Bifascicular block
0.682 0.318 0.000
I45.0 Right fascicular block
0.682 0.318 0.000
N76.8 Other specified inflammation of vagina and vulva
0.682 0.318 0.000
M88 Paget's disease of bone [osteitis deformans]
0.681 0.319 0.000
M17 Gonarthrosis [arthrosis of knee]
0.681 0.319 0.000
M19.8 Other specified arthrosis
0.681 0.319 0.000
M19.2 Other secondary arthrosis
0.681 0.319 0.000
M87 Osteonecrosis
0.681 0.319 0.000
K12.2 Cellulitis and abscess of mouth
0.680 0.320 0.000
K08.2 Atrophy of edentulous alveolar ridge
0.680 0.320 0.000
W07.0 Home
0.680 0.320 0.000
M18 Arthrosis of first carpometacarpal joint
0.680 0.320 0.000
K03 Other diseases of hard tissues of teeth
0.679 0.320 0.000
K10.0 Developmental disorders of jaws
0.679 0.321 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.679 0.321 0.000
K91.9 Postprocedural disorder of digestive system, unspecified
0.679 0.321 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.678 0.322 0.000
N02.2 Diffuse membranous glomerulonephritis
0.678 0.322 0.000
M06.4 Inflammatory polyarthropathy
0.677 0.322 0.000
M54.55 Low back pain (Thoracolumbar region)
0.676 0.323 0.000
M54.54 Low back pain-Thoracic
0.676 0.323 0.000
M54.53 Low back pain-Cervicothoracic
0.676 0.323 0.000
M54.52 Low back pain-Cervical
0.676 0.323 0.000
M54.51 Low back pain-Occipit-atl-axl
0.676 0.323 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.676 0.324 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.676 0.324 0.000
I45.9 Conduction disorder, unspecified
0.675 0.325 0.000
K14.9 Disease of tongue, unspecified
0.675 0.325 0.000
K55-K64 Other diseases of intestines
0.675 0.325 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.674 0.326 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.673 0.327 0.000
M06.8 Other specified rheumatoid arthritis
0.672 0.328 0.000
M06.2 Rheumatoid bursitis
0.672 0.328 0.000
M06.1 Adult-onset Still's disease
0.672 0.328 0.000
S32 Fracture of lumbar spine and pelvis
0.672 0.328 0.000
O74 Complications of anaesthesia during labour and delivery
0.671 0.329 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.671 0.329 0.000
O61 Failed induction of labour
0.671 0.329 0.000
O60 Preterm delivery
0.671 0.329 0.000
O86 Other puerperal infections
0.671 0.329 0.000
K02 Dental caries
0.671 0.329 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.670 0.330 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.670 0.330 0.000
Y85.0 Sequelae of motor-vehicle accident
0.670 0.330 0.000
M54.36 Sciatica (Lumbar region)
0.670 0.330 0.000
I08.9 Multiple valve disease, unspecified
0.669 0.331 0.000
Z35.0 Supervision of pregnancy with history of infertility
0.669 0.331 0.000
M22 Disorders of patella
0.669 0.331 0.000
M46.4 Discitis, unspecified
0.668 0.332 0.000
H81 Disorders of vestibular function
0.668 0.332 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.667 0.333 0.000
Y45.0 Opioids and related analgesics
0.667 0.333 0.000
O42.9 Premature rupture of membranes, unspecified
0.666 0.334 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.665 0.335 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.664 0.336 0.000
K65-K67 Diseases of peritoneum
0.663 0.337 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.662 0.338 0.000
W06.9 Unspecified place
0.661 0.339 0.000
K91.4 Colostomy and enterostomy malfunction
0.661 0.339 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.660 0.339 0.000
W10 Fall on and from stairs and steps
0.660 0.340 0.000
M54.1 Radiculopathy
0.658 0.342 0.000
M19.01 Primary arthrosis of other joints (Shoulder region)
0.658 0.342 0.000
M19.03 Primary arthrosis of other joints (Forearm)
0.658 0.342 0.000
K60 Fissure and fistula of anal and rectal regions
0.658 0.342 0.000
B15-B19 Viral hepatitis
0.658 0.342 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.657 0.343 0.000
O69.9 Labour and delivery complicated by cord complication, unspecified
0.656 0.344 0.000
O69.5 Labour and delivery complicated by vascular lesion of cord
0.656 0.344 0.000
O69.4 Labour and delivery complicated by vasa praevia
0.656 0.344 0.000
O69.3 Labour and delivery complicated by short cord
0.656 0.344 0.000
O69.0 Labour and delivery complicated by prolapse of cord
0.656 0.344 0.000
I07 Rheumatic tricuspid valve diseases
0.656 0.344 0.000
K08.0 Exfoliation of teeth due to systemic causes
0.656 0.344 0.000
M85 Other disorders of bone density and structure
0.655 0.345 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.654 0.346 0.000
Y40.0 Penicillins
0.653 0.347 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.653 0.347 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.653 0.347 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.653 0.347 0.000
N06 Isolated proteinuria with specified morphological lesion
0.653 0.347 0.000
N01 Rapidly progressive nephritic syndrome
0.653 0.347 0.000
N00 Acute nephritic syndrome
0.653 0.347 0.000
M21.1 Varus deformity, not elsewhere classified
0.652 0.348 0.000
M54.6 Pain in thoracic spine
0.650 0.350 0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified
0.649 0.351 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.649 0.351 0.000
M47.8 Other spondylosis
0.649 0.351 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.648 0.351 0.000
M19.1 Posttraumatic arthrosis of other joints
0.648 0.352 0.000
M71 Other bursopathies
0.647 0.353 0.000
N76.3 Subacute and chronic vulvitis
0.647 0.353 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.647 0.353 0.000
M75.5 Bursitis of shoulder
0.647 0.353 0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.646 0.354 0.000
M90 Osteopathies in diseases classified elsewhere
0.646 0.354 0.000
V20-V29 Motorcycle rider injured in transport accident
0.645 0.354 0.000
H81.0 Meniere's disease
0.646 0.354 0.000
M48 Other spondylopathies
0.645 0.355 0.000
I51.7 Cardiomegaly
0.643 0.357 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.642 0.357 0.000
M72 Fibroblastic disorders
0.642 0.358 0.000
D75.8 Other specified diseases of blood and blood-forming organs
0.641 0.359 0.000
K60.2 Anal fissure, unspecified
0.641 0.359 0.000
Y42.7 Androgens and anabolic congeners
0.640 0.360 0.000
K52 Other non-infective gastro-enteritis and colitis
0.640 0.360 0.000
Y40.7 Antifungal antibiotics, systemically used
0.639 0.361 0.000
Y40.6 Rifamycins
0.639 0.361 0.000
Y40.4 Tetracyclines
0.639 0.361 0.000
Y40.3 Macrolides
0.639 0.361 0.000
Y40.2 Chloramphenicol group
0.639 0.361 0.000
Y42.5 Other oestrogens and progestogens
0.639 0.361 0.000
I26 Pulmonary embolism
0.638 0.361 0.000
M24.2 Disorder of ligament
0.638 0.362 0.000
O71.4 Obstetric high vaginal laceration alone
0.638 0.362 0.000
M47.2 Other spondylosis with radiculopathy
0.637 0.363 0.000
I46.9 Cardiac arrest, unspecified
0.637 0.363 0.000
Y57 Other and unspecified drugs and medicaments
0.637 0.363 0.000
W20-W49 Exposure to inanimate mechanical forces
0.637 0.363 0.000
K05 Gingivitis and periodontal diseases
0.637 0.363 0.000
M83 Adult osteomalacia
0.636 0.364 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.635 0.365 0.000
M25 Other joint disorders, not elsewhere classified
0.635 0.365 0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.635 0.365 0.000
W06.0 Home
0.634 0.366 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.633 0.367 0.000
Q80-Q89 Other congenital malformations
0.633 0.367 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.632 0.368 0.000
O16 Unspecified maternal hypertension
0.632 0.368 0.000
M89.9 Disorder of bone, unspecified
0.632 0.368 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.631 0.369 0.000
I35 Nonrheumatic aortic valve disorders
0.630 0.370 0.000
W08 Fall involving other furniture
0.629 0.370 0.000
O41 Other disorders of amniotic fluid and membranes
0.629 0.371 0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.629 0.371 0.000
H60-H62 Diseases of external ear
0.629 0.371 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.629 0.371 0.000
I27.0 Primary pulmonary hypertension
0.629 0.371 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.628 0.371 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.628 0.371 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.628 0.371 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.628 0.371 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.628 0.371 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.628 0.371 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.628 0.371 0.000
N17.8 Other acute renal failure
0.628 0.371 0.000
N17.2 Acute renal failure with medullary necrosis
0.628 0.371 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.628 0.371 0.000
N17.0 Acute renal failure with tubular necrosis
0.628 0.371 0.000
Y46.6 Other and unspecified antiepileptics
0.628 0.372 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.628 0.372 0.000
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere
0.628 0.372 0.000
M34 Systemic sclerosis
0.628 0.372 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.628 0.372 0.000
Y43 Primarily systemic agents
0.628 0.372 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.628 0.372 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.627 0.373 0.000
N18.4 Chronic kidney disease, stage 4
0.627 0.373 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.627 0.373 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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