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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs76338037
log Bayes Factor = 17.1925
Chromosome 5   position 18,496,375  (GRCh37) Explore rs76338037 on Ensembl!
Variant rs76338037 is part of Cluster X0161

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
0.999 0.001 0.000
N30-N39 Other diseases of urinary system
0.999 0.001 0.000
M45-M49 Spondylopathies
0.998 0.002 0.000
M15-M19 Arthrosis
0.997 0.003 0.000
M47 Spondylosis
0.994 0.006 0.000
M19 Other arthrosis
0.991 0.009 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.989 0.011 0.000
N32 Other disorders of bladder
0.989 0.011 0.000
M19.9 Arthrosis, unspecified
0.988 0.012 0.000
Chapter XX External causes of morbidity and mortality
0.986 0.014 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.986 0.014 0.000
M47.8 Other spondylosis
0.983 0.017 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.978 0.022 0.000
M50-M54 Other dorsopathies
0.976 0.024 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.973 0.027 0.000
R30-R39 Symptoms and signs involving the urinary system
0.972 0.028 0.000
Chapter II Neoplasms
0.970 0.030 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.967 0.033 0.000
Chapter XXI Factors influencing health status and contact with health services
0.959 0.041 0.000
M17 Gonarthrosis [arthrosis of knee]
0.959 0.041 0.000
M47.86 Other spondylosis (Lumbar region)
0.958 0.042 0.000
Chapter X Diseases of the respiratory system
0.957 0.043 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.956 0.044 0.000
S00-S09 Injuries to the head
0.956 0.044 0.000
N30 Cystitis
0.952 0.048 0.000
M20-M25 Other joint disorders
0.952 0.048 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.948 0.052 0.000
M54 Dorsalgia
0.946 0.054 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.945 0.055 0.000
N32.8 Other specified disorders of bladder
0.940 0.060 0.000
Z51 Other medical care
0.936 0.064 0.000
M54.5 Low back pain
0.926 0.074 0.000
R32 Unspecified urinary incontinence
0.922 0.078 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.921 0.079 0.000
M17.9 Gonarthrosis, unspecified
0.920 0.080 0.000
C64-C68 Malignant neoplasms of urinary tract
0.919 0.081 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.916 0.084 0.000
S01 Open wound of head
0.915 0.085 0.000
M25 Other joint disorders, not elsewhere classified
0.915 0.085 0.000
R06 Abnormalities of breathing
0.914 0.086 0.000
M47.9 Spondylosis, unspecified
0.907 0.093 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.906 0.094 0.000
R00 Abnormalities of heart beat
0.903 0.097 0.000
N10-N16 Renal tubulo-interstitial diseases
0.902 0.098 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.902 0.098 0.000
D00-D09 In situ neoplasms
0.900 0.100 0.000
N32.0 Bladder-neck obstruction
0.898 0.102 0.000
Z51.0 Radiotherapy session
0.897 0.103 0.000
L60-L75 Disorders of skin appendages
0.895 0.105 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.893 0.107 0.000
R06.5 Mouth breathing
0.892 0.108 0.000
S70-S79 Injuries to the hip and thigh
0.890 0.110 0.000
M47.82 Other spondylosis (Cervical region)
0.888 0.112 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.887 0.113 0.000
C15-C26 Malignant neoplasms of digestive organs
0.885 0.115 0.000
N32.9 Bladder disorder, unspecified
0.880 0.120 0.000
N39 Other disorders of urinary system
0.878 0.122 0.000
M80-M85 Disorders of bone density and structure
0.877 0.123 0.000
M17.0 Primary gonarthrosis, bilateral
0.875 0.125 0.000
Y83.8 Other surgical procedures
0.873 0.127 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.872 0.128 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.870 0.130 0.000
M25.5 Pain in joint
0.870 0.130 0.000
C67 Malignant neoplasm of bladder
0.869 0.131 0.000
M51 Other intervertebral disk disorders
0.864 0.136 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.864 0.136 0.000
N30.9 Cystitis, unspecified
0.861 0.139 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.860 0.140 0.000
Chapter VII Diseases of the eye and adnexa
0.859 0.141 0.000
R30 Pain associated with micturition
0.858 0.142 0.000
M54.57 Low back pain (Lumbosacral region)
0.856 0.144 0.000
N25-N29 Other disorders of kidney and ureter
0.853 0.147 0.000
L20-L30 Dermatitis and eczema
0.850 0.150 0.000
Z50 Care involving use of rehabilitation procedures
0.845 0.155 0.000
J95-J99 Other diseases of the respiratory system
0.843 0.157 0.000
O36 Maternal care for other known or suspected foetal problems
0.839 0.161 0.000
M05-M14 Inflammatory polyarthropathies
0.838 0.162 0.000
S00 Superficial injury of head
0.837 0.163 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.837 0.163 0.000
O60-O75 Complications of labour and delivery
0.837 0.163 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.833 0.167 0.000
J30-J39 Other diseases of upper respiratory tract
0.830 0.170 0.000
C67.9 Bladder, unspecified
0.828 0.172 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.825 0.175 0.000
Z51.2 Other chemotherapy
0.825 0.175 0.000
S80-S89 Injuries to the knee and lower leg
0.824 0.176 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.823 0.177 0.000
M45 Ankylosing spondylitis
0.823 0.177 0.000
N30.8 Other cystitis
0.823 0.177 0.000
S01.8 Open wound of other parts of head
0.820 0.180 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.820 0.180 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.818 0.182 0.000
J00-J06 Acute upper respiratory infections
0.817 0.183 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.817 0.183 0.000
R02 Gangrene, not elsewhere classified
0.817 0.183 0.000
Z43 Attention to artificial openings
0.817 0.183 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.815 0.185 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.814 0.186 0.000
N39.4 Other specified urinary incontinence
0.813 0.187 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.811 0.189 0.000
Chapter IX Diseases of the circulatory system
0.810 0.190 0.000
R79 Other abnormal findings of blood chemistry
0.810 0.190 0.000
N13 Obstructive and reflux uropathy
0.809 0.191 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.809 0.191 0.000
R00.0 Tachycardia, unspecified
0.808 0.192 0.000
H30-H36 Disorders of choroid and retina
0.807 0.193 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.806 0.194 0.000
R00.1 Bradycardia, unspecified
0.805 0.195 0.000
R50-R69 General symptoms and signs
0.805 0.195 0.000
M86-M90 Other osteopathies
0.804 0.196 0.000
R51 Headache
0.804 0.196 0.000
M40-M43 Deforming dorsopathies
0.802 0.198 0.000
M48 Other spondylopathies
0.800 0.200 0.000
R04 Haemorrhage from respiratory passages
0.800 0.200 0.000
N00-N08 Glomerular diseases
0.798 0.202 0.000
X20-X29 Contact with venomous animals and plants
0.798 0.202 0.000
M70-M79 Other soft tissue disorders
0.796 0.204 0.000
D09 Carcinoma in situ of other and unspecified sites
0.795 0.205 0.000
D80-D89 Certain disorders involving the immune mechanism
0.794 0.206 0.000
Y83.6 Removal of other organ (partial) (total)
0.791 0.209 0.000
S01.4 Open wound of cheek and temporomandibular area
0.791 0.209 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.790 0.210 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.789 0.211 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.787 0.213 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.785 0.215 0.000
R31 Unspecified haematuria
0.784 0.216 0.000
M46 Other inflammatory spondylopathies
0.781 0.219 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.781 0.219 0.000
R34 Anuria and oliguria
0.777 0.223 0.000
L72.1 Trichilemmal cyst
0.776 0.224 0.000
Z51.8 Other specified medical care
0.776 0.224 0.000
M21 Other acquired deformities of limbs
0.775 0.225 0.000
M65-M68 Disorders of synovium and tendon
0.775 0.225 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.774 0.226 0.000
I60-I69 Cerebrovascular diseases
0.773 0.227 0.000
N72 Inflammatory disease of cervix uteri
0.772 0.228 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.770 0.230 0.000
M60-M63 Disorders of muscles
0.767 0.233 0.000
O47 False labour
0.767 0.233 0.000
J98 Other respiratory disorders
0.766 0.234 0.000
R47-R49 Symptoms and signs involving speech and voice
0.764 0.236 0.000
S01.5 Open wound of lip and oral cavity
0.764 0.236 0.000
D60-D64 Aplastic and other anaemias
0.763 0.237 0.000
S90-S99 Injuries to the ankle and foot
0.763 0.237 0.000
S50-S59 Injuries to the elbow and forearm
0.763 0.237 0.000
M31 Other necrotising vasculopathies
0.762 0.237 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.761 0.239 0.000
C20 Malignant neoplasm of rectum
0.759 0.241 0.000
M54.59 Low back pain (Site unspecified)
0.753 0.247 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.752 0.248 0.000
S01.2 Open wound of nose
0.752 0.248 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.750 0.250 0.000
M34 Systemic sclerosis
0.750 0.250 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.749 0.251 0.000
S72 Fracture of femur
0.749 0.251 0.000
M19.94 Arthrosis, unspecified (Hand)
0.749 0.251 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.748 0.251 0.000
O40 Polyhydramnios
0.748 0.252 0.000
J09-J18 Influenza and pneumonia
0.748 0.252 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.747 0.253 0.000
H35 Other retinal disorders
0.747 0.253 0.000
M25.51 Pain in joint (Shoulder region)
0.746 0.254 0.000
M19.98 Arthrosis, unspecified (Other)
0.746 0.254 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.745 0.255 0.000
M51.2 Other specified intervertebral disk displacement
0.745 0.255 0.000
N35 Urethral stricture
0.745 0.255 0.000
M47.2 Other spondylosis with radiculopathy
0.743 0.257 0.000
L40-L45 Papulosquamous disorders
0.742 0.258 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.741 0.259 0.000
O00-O08 Pregnancy with abortive outcome
0.741 0.259 0.000
Z47 Other orthopaedic follow-up care
0.741 0.259 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.738 0.262 0.000
M91-M94 Chondropathies
0.737 0.263 0.000
N30.2 Other chronic cystitis
0.736 0.264 0.000
M80 Osteoporosis with pathological fracture
0.735 0.265 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.735 0.265 0.000
M54.50 Low back pain (Multiple sites in spine)
0.734 0.266 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.734 0.266 0.000
N31.8 Other neuromuscular dysfunction of bladder
0.734 0.266 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.733 0.266 0.000
R30.0 Dysuria
0.733 0.267 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.733 0.267 0.000
M54.4 Lumbago with sciatica
0.733 0.267 0.000
Z43.2 Attention to ileostomy
0.733 0.267 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.732 0.268 0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified
0.729 0.271 0.000
M54.2 Cervicalgia
0.728 0.272 0.000
Z51.5 Palliative care
0.727 0.273 0.000
Y83.5 Amputation of limb(s)
0.727 0.273 0.000
C60-C63 Malignant neoplasms of male genital organs
0.726 0.274 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.726 0.274 0.000
Z54 Convalescence
0.726 0.274 0.000
S06 Intracranial injury
0.725 0.275 0.000
D04 Carcinoma in situ of skin
0.724 0.276 0.000
M25.3 Other instability of joint
0.723 0.277 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.722 0.278 0.000
Chapter VIII Diseases of the ear and mastoid process
0.722 0.278 0.000
N20-N23 Urolithiasis
0.722 0.278 0.000
S70 Superficial injury of hip and thigh
0.720 0.280 0.000
M07 Psoriatic and enteropathic arthropathies
0.720 0.280 0.000
D09.0 Bladder
0.719 0.281 0.000
N36 Other disorders of urethra
0.719 0.281 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.719 0.281 0.000
S20-S29 Injuries to the thorax
0.718 0.282 0.000
I69 Sequelae of cerebrovascular disease
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
N37 Urethral disorders in diseases classified elsewhere
0.716 0.284 0.000
N34 Urethritis and urethral syndrome
0.716 0.284 0.000
N33 Bladder disorders in diseases classified elsewhere
0.716 0.284 0.000
M25.50 Pain in joint (Multiple sites)
0.716 0.284 0.000
O41 Other disorders of amniotic fluid and membranes
0.716 0.284 0.000
M49 Spondylopathies in diseases classified elsewhere
0.715 0.284 0.000
M15 Polyarthrosis
0.715 0.285 0.000
M22 Disorders of patella
0.715 0.285 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.714 0.286 0.000
R80 Isolated proteinuria
0.714 0.286 0.000
D06 Carcinoma in situ of cervix uteri
0.713 0.287 0.000
S81 Open wound of lower leg
0.713 0.287 0.000
Z29 Need for other prophylactic measures
0.713 0.287 0.000
M47.1 Other spondylosis with myelopathy
0.712 0.287 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.712 0.287 0.000
S00.8 Superficial injury of other parts of head
0.713 0.287 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.713 0.287 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.712 0.288 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.712 0.288 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.712 0.288 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.711 0.289 0.000
O46.9 Antepartum haemorrhage, unspecified
0.711 0.289 0.000
M19.8 Other specified arthrosis
0.710 0.290 0.000
M19.2 Other secondary arthrosis
0.710 0.290 0.000
M19.1 Posttraumatic arthrosis of other joints
0.710 0.290 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.710 0.290 0.000
R25 Abnormal involuntary movements
0.710 0.290 0.000
C25 Malignant neoplasm of pancreas
0.710 0.290 0.000
M25.4 Effusion of joint
0.709 0.291 0.000
T79-T79 Certain early complications of trauma
0.709 0.291 0.000
T33-T35 Frostbite
0.709 0.291 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.709 0.291 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.709 0.291 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.709 0.291 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.709 0.291 0.000
T00-T07 Injuries involving multiple body regions
0.709 0.291 0.000
S10-S19 Injuries to the neck
0.709 0.291 0.000
N32.4 Rupture of bladder, nontraumatic
0.709 0.291 0.000
N32.2 Vesical fistula, not elsewhere classified
0.709 0.291 0.000
N32.1 Vesicointestinal fistula
0.709 0.291 0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified
0.709 0.291 0.000
R01 Cardiac murmurs and other cardiac sounds
0.709 0.291 0.000
M51.8 Other specified intervertebral disk disorders
0.709 0.291 0.000
S60-S69 Injuries to the wrist and hand
0.708 0.291 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.708 0.292 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.708 0.292 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.707 0.293 0.000
Y35-Y36 Legal intervention and operations of war
0.707 0.293 0.000
Y10-Y34 Event of undetermined intent
0.707 0.293 0.000
Y00-Y09 Assault
0.707 0.293 0.000
X85-X99 Assault
0.707 0.293 0.000
X60-X84 Intentional self-harm
0.707 0.293 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.707 0.293 0.000
X50-X57 Overexertion, travel and privation
0.707 0.293 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.707 0.293 0.000
X30-X39 Exposure to forces of nature
0.707 0.293 0.000
X10-X19 Contact with heat and hot substances
0.707 0.293 0.000
X00-X09 Exposure to smoke, fire and flames
0.707 0.293 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.707 0.293 0.000
W75-W84 Other accidental threats to breathing
0.707 0.293 0.000
W65-W74 Accidental drowning and submersion
0.707 0.293 0.000
W50-W64 Exposure to animate mechanical forces
0.707 0.293 0.000
V98-V99 Other and unspecified transport accidents
0.707 0.293 0.000
V95-V97 Air and space transport accidents
0.707 0.293 0.000
V90-V94 Water transport accidents
0.707 0.293 0.000
V80-V89 Other land transport accidents
0.707 0.293 0.000
V70-V79 Bus occupant injured in transport accident
0.707 0.293 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.707 0.293 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.707 0.293 0.000
V40-V49 Car occupant injured in transport accident
0.707 0.293 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.707 0.293 0.000
V20-V29 Motorcycle rider injured in transport accident
0.707 0.293 0.000
V01-V09 Pedestrian injured in transport accident
0.707 0.293 0.000
Chapter VI Diseases of the nervous system
0.707 0.293 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.707 0.293 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.707 0.293 0.000
O85-O92 Complications predominantly related to the puerperium
0.707 0.293 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.705 0.295 0.000
M47.89 Other spondylosis (Site unspecified)
0.705 0.295 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.705 0.295 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.705 0.295 0.000
M47.84 Other spondylosis (Thoracic region)
0.705 0.295 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.705 0.295 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.705 0.295 0.000
L50-L54 Urticaria and erythema
0.705 0.295 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.705 0.295 0.000
V10-V19 Pedal cyclist injured in transport accident
0.704 0.296 0.000
H43-H45 Disorders of vitreous body and globe
0.704 0.296 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.704 0.296 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.704 0.296 0.000
O36.5 Maternal care for poor foetal growth
0.703 0.297 0.000
L91 Hypertrophic disorders of skin
0.702 0.298 0.000
S79 Other and unspecified injuries of hip and thigh
0.702 0.298 0.000
L10-L14 Bullous disorders
0.701 0.299 0.000
R74 Abnormal serum enzyme levels
0.701 0.299 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.701 0.299 0.000
S40-S49 Injuries to the shoulder and upper arm
0.701 0.299 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.701 0.299 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.700 0.300 0.000
M53 Other dorsopathies, not elsewhere classified
0.700 0.300 0.000
Z40 Prophylactic surgery
0.700 0.300 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.700 0.300 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.700 0.300 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.700 0.300 0.000
W20-W49 Exposure to inanimate mechanical forces
0.699 0.301 0.000
R30.9 Painful micturition, unspecified
0.699 0.301 0.000
R06.8 Other and unspecified abnormalities of breathing
0.698 0.302 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.697 0.303 0.000
R36 Urethral discharge
0.697 0.303 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.697 0.303 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.697 0.303 0.000
N28.8 Other specified disorders of kidney and ureter
0.697 0.303 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.695 0.305 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.695 0.305 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.695 0.305 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.695 0.305 0.000
M54.3 Sciatica
0.694 0.306 0.000
J20-J22 Other acute lower respiratory infections
0.694 0.306 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.694 0.306 0.000
S00.1 Contusion of eyelid and periocular area
0.693 0.307 0.000
R39 Other symptoms and signs involving the urinary system
0.693 0.307 0.000
L29 Pruritus
0.693 0.307 0.000
N30.3 Trigonitis
0.693 0.307 0.000
O36.6 Maternal care for excessive foetal growth
0.692 0.308 0.000
O30 Multiple gestation
0.692 0.308 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.691 0.308 0.000
R04.2 Haemoptysis
0.691 0.309 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.689 0.311 0.000
T93 Sequelae of injuries of lower limb
0.689 0.311 0.000
J36 Peritonsillar abscess
0.689 0.311 0.000
Y40 Systemic antibiotics
0.687 0.312 0.000
M17.5 Other secondary gonarthrosis
0.687 0.313 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.687 0.313 0.000
M17.3 Other posttraumatic gonarthrosis
0.687 0.313 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.687 0.313 0.000
R26 Abnormalities of gait and mobility
0.687 0.313 0.000
M84 Disorders of continuity of bone
0.687 0.313 0.000
N30.1 Interstitial cystitis (chronic)
0.687 0.313 0.000
S08 Traumatic amputation of part of head
0.685 0.315 0.000
S07 Crushing injury of head
0.685 0.315 0.000
S05 Injury of eye and orbit
0.685 0.315 0.000
S04 Injury of cranial nerves
0.685 0.315 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.685 0.315 0.000
Y84.2 Radiological procedure and radiotherapy
0.684 0.316 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.684 0.316 0.000
J60-J70 Lung diseases due to external agents
0.684 0.316 0.000
M25.57 Pain in joint (Ankle and foot)
0.683 0.317 0.000
N30.4 Irradiation cystitis
0.683 0.317 0.000
N30.0 Acute cystitis
0.683 0.317 0.000
N99-N99 Other disorders of the genitourinary system
0.683 0.317 0.000
S01.3 Open wound of ear
0.683 0.317 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.682 0.318 0.000
M33 Dermatopolymyositis
0.682 0.318 0.000
M32 Systemic lupus erythematosus
0.682 0.318 0.000
M30 Polyarteritis nodosa and related conditions
0.682 0.318 0.000
M54.56 Low back pain (Lumbar region)
0.682 0.318 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.680 0.320 0.000
Z52 Donors of organs and tissues
0.680 0.320 0.000
Z49 Care involving dialysis
0.680 0.320 0.000
Z44 Fitting and adjustment of external prosthetic device
0.680 0.320 0.000
S02 Fracture of skull and facial bones
0.679 0.320 0.000
N76 Other inflammation of vagina and vulva
0.679 0.321 0.000
M54.8 Other dorsalgia
0.678 0.322 0.000
M54.6 Pain in thoracic spine
0.678 0.322 0.000
M54.0 Panniculitis affecting regions of neck and back
0.678 0.322 0.000
O45 Premature separation of placenta [abruptio placentae]
0.678 0.322 0.000
O44 Placenta praevia
0.678 0.322 0.000
O43 Placental disorders
0.678 0.322 0.000
O33 Maternal care for known or suspected disproportion
0.678 0.322 0.000
O31 Complications specific to multiple gestation
0.678 0.322 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.678 0.322 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.677 0.323 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.677 0.323 0.000
L60 Nail disorders
0.676 0.324 0.000
D86 Sarcoidosis
0.675 0.325 0.000
Y44 Agents primarily affecting blood constituents
0.674 0.326 0.000
M35 Other systemic involvement of connective tissue
0.674 0.326 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.674 0.326 0.000
L73 Other follicular disorders
0.673 0.327 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.673 0.327 0.000
J90-J94 Other diseases of pleura
0.672 0.328 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.672 0.328 0.000
Z51.9 Medical care, unspecified
0.671 0.329 0.000
Z51.6 Desensitisation to allergens
0.671 0.329 0.000
Y43 Primarily systemic agents
0.671 0.329 0.000
L85 Other epidermal thickening
0.670 0.330 0.000
O80-O84 Delivery
0.670 0.330 0.000
C50-C50 Malignant neoplasm of breast
0.670 0.330 0.000
T66-T78 Other and unspecified effects of external causes
0.669 0.330 0.000
O42 Premature rupture of membranes
0.669 0.331 0.000
N40-N51 Diseases of male genital organs
0.669 0.331 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.668 0.332 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.667 0.333 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.667 0.333 0.000
N02 Recurrent and persistent haematuria
0.666 0.334 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.665 0.335 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.665 0.335 0.000
Z50.5 Speech therapy
0.665 0.335 0.000
M10 Gout
0.665 0.335 0.000
Z50.2 Alcohol rehabilitation
0.664 0.336 0.000
S80 Superficial injury of lower leg
0.664 0.336 0.000
Z41 Procedures for purposes other than remedying health state
0.664 0.336 0.000
M54.55 Low back pain (Thoracolumbar region)
0.664 0.336 0.000
M54.54 Low back pain-Thoracic
0.664 0.336 0.000
M54.53 Low back pain-Cervicothoracic
0.664 0.336 0.000
M54.52 Low back pain-Cervical
0.664 0.336 0.000
M54.51 Low back pain-Occipit-atl-axl
0.664 0.336 0.000
X23 Contact with hornets, wasps and bees
0.663 0.337 0.000
C09 Malignant neoplasm of tonsil
0.663 0.337 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.663 0.337 0.000
C15 Malignant neoplasm of oesophagus
0.662 0.338 0.000
Y83.4 Other reconstructive surgery
0.661 0.338 0.000
Y84.6 Urinary catheterisation
0.661 0.339 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.661 0.339 0.000
D55-D59 Haemolytic anaemias
0.661 0.339 0.000
M85 Other disorders of bone density and structure
0.661 0.339 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.659 0.341 0.000
C66 Malignant neoplasm of ureter
0.659 0.341 0.000
C65 Malignant neoplasm of renal pelvis
0.659 0.341 0.000
J32 Chronic sinusitis
0.659 0.341 0.000
I71 Aortic aneurysm and dissection
0.659 0.341 0.000
M48.0 Spinal stenosis
0.659 0.341 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.658 0.342 0.000
W00-W19 Falls
0.658 0.342 0.000
Y83.9 Surgical procedure, unspecified
0.657 0.343 0.000
Y83.0 Surgical operation with transplant of whole organ
0.657 0.343 0.000
M25.7 Osteophyte
0.657 0.343 0.000
T90 Sequelae of injuries of head
0.657 0.343 0.000
S01.9 Open wound of head, part unspecified
0.656 0.344 0.000
S01.7 Multiple open wounds of head
0.656 0.344 0.000
M25.9 Joint disorder, unspecified
0.656 0.344 0.000
M25.8 Other specified joint disorders
0.656 0.344 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.656 0.344 0.000
M25.2 Flail joint
0.656 0.344 0.000
M25.1 Fistula of joint
0.656 0.344 0.000
M25.0 Haemarthrosis
0.656 0.344 0.000
R06.7 Sneezing
0.656 0.344 0.000
R06.6 Hiccough
0.656 0.344 0.000
R06.3 Periodic breathing
0.656 0.344 0.000
R06.2 Wheezing
0.656 0.344 0.000
R06.1 Stridor
0.656 0.344 0.000
L84 Corns and callosities
0.656 0.344 0.000
N39.9 Disorder of urinary system, unspecified
0.655 0.345 0.000
R09.1 Pleurisy
0.655 0.345 0.000
H35.8 Other specified retinal disorders
0.655 0.345 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.654 0.346 0.000
M54.1 Radiculopathy
0.654 0.346 0.000
O62 Abnormalities of forces of labour
0.654 0.346 0.000
J98.4 Other disorders of lung
0.654 0.346 0.000
L28 Lichen simplex chronicus and prurigo
0.654 0.346 0.000
C67.2 Lateral wall of bladder
0.652 0.348 0.000
M41 Scoliosis
0.651 0.349 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.650 0.350 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.650 0.350 0.000
M47.94 Spondylosis, unspecified (Thoracic region)
0.650 0.350 0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)
0.650 0.350 0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)
0.650 0.350 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.650 0.350 0.000
L30 Other dermatitis
0.650 0.350 0.000
Z36 Antenatal screening
0.650 0.350 0.000
M89 Other disorders of bone
0.650 0.350 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.650 0.350 0.000
R77 Other abnormalities of plasma proteins
0.650 0.350 0.000
R76 Other abnormal immunological findings in serum
0.650 0.350 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.650 0.350 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.650 0.350 0.000
R71 Abnormality of red blood cells
0.650 0.350 0.000
N32.3 Diverticulum of bladder
0.649 0.350 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.649 0.350 0.000
Y95 Nosocomial condition
0.648 0.352 0.000
R09.0 Asphyxia
0.648 0.352 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.647 0.353 0.000
N15 Other renal tubulo-interstitial diseases
0.647 0.353 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.647 0.353 0.000
N11 Chronic tubulo-interstitial nephritis
0.647 0.353 0.000
N10 Acute tubulo-interstitial nephritis
0.647 0.353 0.000
Y83.3 Surgical operation with formation of external stoma
0.646 0.354 0.000
M81 Osteoporosis without pathological fracture
0.646 0.354 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.645 0.354 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.645 0.354 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.645 0.354 0.000
L72.0 Epidermal cyst
0.646 0.354 0.000
J03 Acute tonsillitis
0.645 0.355 0.000
L27 Dermatitis due to substances taken internally
0.645 0.355 0.000
O63 Long labour
0.644 0.356 0.000
Z35 Supervision of high-risk pregnancy
0.643 0.357 0.000
M67 Other disorders of synovium and tendon
0.643 0.357 0.000
Z50.1 Other physical therapy
0.642 0.358 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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