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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs76404194
log Bayes Factor = 5.06183
Chromosome 11   position 16,826,397  (GRCh37) Explore rs76404194 on Ensembl!
Variant rs76404194 is part of Cluster X0034

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
I20 Angina pectoris
0.000 0.005 0.995
I25.1 Atherosclerotic heart disease
0.000 0.005 0.995
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.006 0.994
I20.9 Angina pectoris, unspecified
0.000 0.009 0.991
I22 Subsequent myocardial infarction
0.000 0.010 0.990
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.023 0.977
I25.2 Old myocardial infarction
0.000 0.033 0.967
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.036 0.964
I21 Acute myocardial infarction
0.000 0.037 0.963
I21.4 Acute subendocardial myocardial infarction
0.000 0.091 0.909
I20.0 Unstable angina
0.000 0.117 0.883
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.147 0.853
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.191 0.809
I25.3 Aneurysm of heart
0.000 0.222 0.778
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.229 0.771
I20.1 Angina pectoris with documented spasm
0.000 0.244 0.756
I21.9 Acute myocardial infarction, unspecified
0.000 0.274 0.726
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.280 0.720
I22.8 Subsequent myocardial infarction of other sites
0.000 0.282 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.288 0.712
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.309 0.691
I25.5 Ischaemic cardiomyopathy
0.000 0.330 0.670
I25.4 Coronary artery aneurysm
0.000 0.353 0.646
I23 Certain current complications following acute myocardial infarction
0.000 0.420 0.579
Z13.9 Special screening examination, unspecified
0.000 0.469 0.531
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.485 0.515
I25.0 Atherosclerotic cardiovascular disease, so described
0.001 0.511 0.489
I20.8 Other forms of angina pectoris
0.000 0.558 0.442
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.584 0.415
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.584 0.415
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.584 0.415
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.584 0.415
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.584 0.415
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.584 0.415
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.584 0.415
I10 Essential (primary) hypertension
0.000 0.648 0.352
I10-I15 Hypertensive diseases
0.000 0.652 0.348
Chapter IX Diseases of the circulatory system
0.000 0.653 0.347
I05-I09 Chronic rheumatic heart diseases
0.000 0.672 0.328
I05 Rheumatic mitral valve diseases
0.000 0.695 0.305
I07 Rheumatic tricuspid valve diseases
0.000 0.708 0.292
I23.8 Other current complications following acute myocardial infarction
0.001 0.721 0.278
I24 Other acute ischaemic heart diseases
0.001 0.731 0.269
I07.1 Tricuspid insufficiency
0.000 0.733 0.267
I05.0 Mitral stenosis
0.000 0.734 0.266
I11 Hypertensive heart disease
0.000 0.736 0.264
I12 Hypertensive renal disease
0.000 0.737 0.263
I05.2 Mitral stenosis with insufficiency
0.000 0.745 0.255
I13 Hypertensive heart and renal disease
0.000 0.750 0.249
I00-I02 Acute rheumatic fever
0.000 0.751 0.249
I09 Other rheumatic heart diseases
0.000 0.765 0.235
I06 Rheumatic aortic valve diseases
0.000 0.765 0.235
I05.9 Mitral valve disease, unspecified
0.000 0.766 0.234
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.771 0.229
I05.1 Rheumatic mitral insufficiency
0.000 0.774 0.226
I05.8 Other mitral valve diseases
0.000 0.781 0.219
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.787 0.213
I07.9 Tricuspid valve disease, unspecified
0.000 0.790 0.210
I07.8 Other tricuspid valve diseases
0.000 0.790 0.210
I07.2 Tricuspid stenosis with insufficiency
0.000 0.790 0.210
I07.0 Tricuspid stenosis
0.000 0.790 0.210
I99 Other and unspecified disorders of circulatory system
0.000 0.794 0.206
I15 Secondary hypertension
0.000 0.795 0.205
I12.9 Hypertensive renal disease without renal failure
0.000 0.795 0.205
I24.8 Other forms of acute ischaemic heart disease
0.000 0.806 0.194
I08 Multiple valve diseases
0.000 0.815 0.185
I12.0 Hypertensive renal disease with renal failure
0.000 0.816 0.184
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.821 0.179
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.821 0.179
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.821 0.179
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.821 0.179
I02 Rheumatic chorea
0.000 0.821 0.179
I01 Rheumatic fever with heart involvement
0.000 0.821 0.179
I00 Rheumatic fever without mention of heart involvement
0.000 0.821 0.179
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.823 0.177
I24.1 Dressler's syndrome
0.001 0.824 0.175
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.831 0.169
I06.8 Other rheumatic aortic valve diseases
0.000 0.831 0.169
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.831 0.169
I06.1 Rheumatic aortic insufficiency
0.000 0.831 0.169
I06.0 Rheumatic aortic stenosis
0.000 0.831 0.169
I09.9 Rheumatic heart disease, unspecified
0.000 0.831 0.169
I09.8 Other specified rheumatic heart diseases
0.000 0.831 0.169
I09.2 Chronic rheumatic pericarditis
0.000 0.831 0.169
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.831 0.169
I09.0 Rheumatic myocarditis
0.000 0.831 0.169
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.838 0.162
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.840 0.160
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.841 0.159
I15.9 Seconday hypertension, unspecified
0.000 0.853 0.147
I15.8 Other secondary hypertension
0.000 0.853 0.147
I15.2 Hypertension secondary to endocrine disorders
0.000 0.853 0.147
I15.0 Renovascular hypertension
0.000 0.853 0.147
I08.9 Multiple valve disease, unspecified
0.000 0.867 0.133
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.867 0.133
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.868 0.132
I08.8 Other multiple valve diseases
0.000 0.869 0.131
I97.1 Other functional disturbances following cardiac surgery
0.000 0.870 0.130
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.872 0.128
I01.8 Other acute rheumatic heart disease
0.000 0.872 0.128
I01.2 Acute rheumatic myocarditis
0.000 0.872 0.128
I01.1 Acute rheumatic endocarditis
0.000 0.872 0.128
I01.0 Acute rheumatic pericarditis
0.000 0.872 0.128
I02.9 Rheumatic chorea without heart involvement
0.000 0.872 0.128
I02.0 Rheumatic chorea with heart involvement
0.000 0.872 0.128
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.879 0.120
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.883 0.116
I97.0 Postcardiotomy syndrome
0.000 0.883 0.116
I28 Other diseases of pulmonary vessels
0.000 0.885 0.115
I08.0 Disorders of both mitral and aortic valves
0.000 0.891 0.109
I15.1 Hypertension secondary to other renal disorders
0.001 0.897 0.102
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.905 0.095
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.905 0.095
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.905 0.095
I98.0 Cardiovascular syphilis
0.000 0.905 0.095
I27 Other pulmonary heart diseases
0.000 0.908 0.092
I24.9 Acute ischaemic heart disease, unspecified
0.001 0.908 0.091
Z13 Special screening examination for other diseases and disorders
0.000 0.911 0.089
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.913 0.086
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.001 0.915 0.084
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.917 0.082
I28.8 Other specified diseases of pulmonary vessels
0.000 0.917 0.082
I28.1 Aneurysm of pulmonary artery
0.000 0.917 0.082
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.917 0.082
I95 Hypotension
0.000 0.919 0.081
I60-I69 Cerebrovascular diseases
0.000 0.920 0.080
Z13.6 Special screening examination for cardiovascular disorders
0.000 0.927 0.073
I26 Pulmonary embolism
0.000 0.930 0.070
Z13.3 Special screening examination for mental and behavioural disorders
0.000 0.930 0.070
I60 Subarachnoid haemorrhage
0.000 0.932 0.068
I27.1 Kyphoscoliotic heart disease
0.000 0.933 0.066
I27.9 Pulmonary heart disease, unspecified
0.000 0.935 0.065
E11.4 With neurological complications
0.000 0.935 0.065
I95.2 Hypotension due to drugs
0.000 0.936 0.064
Z13.8 Special screening examination for other specified diseases and disorders
0.000 0.936 0.064
Z13.7 Special screening examination for congenital malformations, deformations and chromosomal abnormalities
0.000 0.936 0.064
Z13.4 Special screening examination for certain developmental disorders in childhood
0.000 0.936 0.064
I27.2 Other secondary pulmonary hypertension
0.000 0.936 0.064
I95.0 Idiopathic hypotension
0.000 0.937 0.062
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.938 0.062
E11 Non-insulin-dependent diabetes mellitus
0.000 0.938 0.062
I69 Sequelae of cerebrovascular disease
0.000 0.939 0.061
I27.0 Primary pulmonary hypertension
0.000 0.940 0.060
I61 Intracerebral haemorrhage
0.000 0.940 0.060
I27.8 Other specified pulmonary heart diseases
0.000 0.942 0.058
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.942 0.058
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.942 0.058
E10 Insulin-dependent diabetes mellitus
0.000 0.943 0.057
E10-E14 Diabetes mellitus
0.000 0.944 0.056
I60.8 Other subarachnoid haemorrhage
0.000 0.944 0.056
Z13.2 Special screening examination for nutritional disorders
0.000 0.944 0.056
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.944 0.056
E11.3 With ophthalmic complications
0.000 0.944 0.056
Z13.1 Special screening examination for diabetes mellitus
0.000 0.945 0.055
E10.9 Without complications
0.000 0.946 0.054
E11.2 With renal complications
0.000 0.947 0.053
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.947 0.053
E10.4 With neurological complications
0.000 0.947 0.053
Z13.5 Special screening examination for eye and ear disorders
0.000 0.947 0.052
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.948 0.052
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.948 0.052
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.948 0.052
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.948 0.052
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.951 0.049
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.951 0.049
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.951 0.049
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.951 0.049
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.951 0.049
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.951 0.049
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.951 0.049
E10.3 With ophthalmic complications
0.000 0.952 0.048
I95.8 Other hypotension
0.000 0.952 0.048
E11.0 With coma
0.000 0.952 0.048
E11.6 With other specified complications
0.000 0.953 0.047
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.953 0.047
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.953 0.046
Z13.83 Encounter for screening for respiratory disorder NEC
0.000 0.954 0.046
Z13.82 Encounter for screening for musculoskeletal disorder
0.000 0.954 0.046
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.955 0.045
I61.8 Other intracerebral haemorrhage
0.000 0.955 0.045
E11.7 With multiple complications
0.000 0.955 0.045
I95.1 Orthostatic hypotension
0.000 0.955 0.044
I67 Other cerebrovascular diseases
0.000 0.956 0.044
I70-I79 Diseases of arteries, arterioles and capillaries
0.001 0.956 0.043
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.956 0.043
E13 Other specified diabetes mellitus
0.000 0.957 0.043
E10.0 With coma
0.000 0.957 0.043
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.957 0.043
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.957 0.043
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.958 0.042
E10.8 With unspecified complications
0.000 0.958 0.042
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.958 0.042
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.958 0.041
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.958 0.041
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.958 0.041
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.958 0.041
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.958 0.041
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.958 0.041
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.958 0.041
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.958 0.041
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.958 0.041
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.958 0.041
I68.0 Cerebral amyloid angiopathy
0.000 0.958 0.041
I67.1 Cerebral aneurysm, nonruptured
0.000 0.959 0.041
E10.7 With multiple complications
0.000 0.959 0.041
E10.2 With renal complications
0.000 0.959 0.041
E12 Malnutrition-related diabetes mellitus
0.000 0.959 0.041
E10.6 With other specified complications
0.000 0.960 0.040
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.960 0.040
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.960 0.040
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.960 0.040
I65.1 Occlusion and stenosis of basilar artery
0.000 0.960 0.040
I65.2 Occlusion and stenosis of carotid artery
0.000 0.960 0.040
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.960 0.039
E14 Unspecified diabetes mellitus
0.000 0.960 0.040
E11.5 With peripheral circulatory complications
0.000 0.960 0.040
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.961 0.039
E11.9 Without complications
0.000 0.961 0.039
E11.8 With unspecified complications
0.000 0.961 0.039
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.961 0.038
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.962 0.038
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.963 0.037
E10.5 With peripheral circulatory complications
0.000 0.963 0.037
I62 Other nontraumatic intracranial haemorrhage
0.000 0.963 0.036
I69.3 Sequelae of cerebral infarction
0.000 0.964 0.036
E11.1 With ketoacidosis
0.000 0.965 0.035
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.965 0.035
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.966 0.034
E13.9 Without complications
0.000 0.966 0.033
I74 Arterial embolism and thrombosis
0.000 0.967 0.033
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.968 0.032
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.968 0.032
I67.5 Moyamoya disease
0.000 0.968 0.032
I67.4 Hypertensive encephalopathy
0.000 0.968 0.032
I67.3 Progressive vascular leukoencephalopathy
0.000 0.968 0.032
E14.3 With ophthalmic complications
0.000 0.968 0.032
E13.8 With unspecified complications
0.000 0.969 0.031
E13.7 With multiple complications
0.000 0.969 0.031
E13.6 With other specified complications
0.000 0.969 0.031
E13.5 With peripheral circulatory complications
0.000 0.969 0.031
E13.4 With neurological complications
0.000 0.969 0.031
E13.3 With ophthalmic complications
0.000 0.969 0.031
E13.2 With renal complications
0.000 0.969 0.031
E13.1 With ketoacidosis
0.000 0.969 0.031
E13.0 With coma
0.000 0.969 0.031
E10.1 With ketoacidosis
0.000 0.969 0.031
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.969 0.031
I78 Diseases of capillaries
0.000 0.970 0.030
E12.9 Without complications
0.000 0.971 0.029
E12.8 With unspecified complications
0.000 0.971 0.029
E12.7 With multiple complications
0.000 0.971 0.029
E12.6 With other specified complications
0.000 0.971 0.029
E12.5 With peripheral circulatory complications
0.000 0.971 0.029
E12.4 With neurological complications
0.000 0.971 0.029
E12.3 With ophthalmic complications
0.000 0.971 0.029
E12.2 With renal complications
0.000 0.971 0.029
E12.1 With ketoacidosis
0.000 0.971 0.029
E12.0 With coma
0.000 0.971 0.029
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.001 0.971 0.028
I70 Atherosclerosis
0.006 0.971 0.023
E14.7 With multiple complications
0.000 0.971 0.029
E14.6 With other specified complications
0.000 0.971 0.029
E14.5 With peripheral circulatory complications
0.000 0.971 0.029
E14.4 With neurological complications
0.000 0.971 0.029
E14.2 Withrenal complications
0.000 0.971 0.029
E14.1 With ketoacidosis
0.000 0.971 0.029
E14.0 With coma
0.000 0.971 0.029
I72 Other aneurysm
0.000 0.972 0.028
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.973 0.027
I62.1 Nontraumatic extradural haemorrhage
0.000 0.973 0.026
E14.8 With unspecified complications
0.000 0.973 0.026
I74.8 Embolism and thrombosis of other arteries
0.000 0.974 0.026
I73 Other peripheral vascular diseases
0.000 0.974 0.026
E14.9 Without complications
0.000 0.975 0.025
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.976 0.024
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.976 0.024
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.976 0.024
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.023 0.976 0.001
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.977 0.023
I70.2 Atherosclerosis of arteries of the extremities
0.013 0.977 0.010
I85 Oesophageal varices
0.000 0.977 0.023
I67.8 Other specified cerebrovascular diseases
0.000 0.977 0.023
I72.3 Aneurysm of iliac artery
0.000 0.978 0.022
I78.8 Other diseases of capillaries
0.000 0.978 0.022
I78.1 Naevus, nonneoplastic
0.000 0.978 0.022
I67.2 Cerebral atherosclerosis
0.000 0.978 0.022
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.978 0.022
I78.9 Disease of capillaries, unspecified
0.000 0.978 0.022
I73.0 Raynaud's syndrome
0.000 0.978 0.022
I72.8 Aneurysm of other specified arteries
0.000 0.978 0.021
I70.0 Atherosclerosis of aorta
0.004 0.979 0.018
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.001 0.979 0.020
I79.1 Aortitis in diseases classified elsewhere
0.001 0.979 0.020
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.001 0.979 0.020
I70.9 Generalised and unspecified atherosclerosis
0.004 0.979 0.017
I70.8 Atherosclerosis of other arteries
0.004 0.979 0.017
I30-I52 Other forms of heart disease
0.000 0.979 0.021
I38 Endocarditis, valve unspecified
0.000 0.980 0.020
I72.9 Aneurysm of unspecified site
0.000 0.980 0.020
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.980 0.020
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.980 0.020
I72.2 Aneurysm of renal artery
0.000 0.980 0.020
I72.1 Aneurysm of artery of upper extremity
0.000 0.980 0.020
I80 Phlebitis and thrombophlebitis
0.000 0.980 0.020
I70.1 Atherosclerosis of renal artery
0.004 0.980 0.015
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.980 0.020
I81 Portal vein thrombosis
0.000 0.981 0.019
I74.5 Embolism and thrombosis of iliac artery
0.000 0.981 0.019
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.981 0.019
I85.9 Oesophageal varices without bleeding
0.000 0.981 0.019
I88 Nonspecific lymphadenitis
0.000 0.981 0.019
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.981 0.018
I85.0 Oesophageal varices with bleeding
0.000 0.982 0.018
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.001 0.982 0.018
I77 Other disorders of arteries and arterioles
0.001 0.982 0.017
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.982 0.018
I49 Other cardiac arrhythmias
0.000 0.982 0.018
I87 Other disorders of veins
0.000 0.982 0.018
I49.9 Cardiac arrhythmia, unspecified
0.000 0.982 0.018
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.000 0.983 0.017
I37 Pulmonary valve disorders
0.000 0.983 0.017
I89.0 Lymphoedema, not elsewhere classified
0.000 0.983 0.017
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.009 0.983 0.008
I46 Cardiac arrest
0.000 0.983 0.017
I73.8 Other specified peripheral vascular diseases
0.000 0.983 0.017
I72.0 Aneurysm of carotid artery
0.001 0.984 0.016
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.984 0.016
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.000 0.984 0.016
I33 Acute and subacute endocarditis
0.000 0.984 0.016
I71 Aortic aneurysm and dissection
0.000 0.984 0.016
I72.4 Aneurysm of artery of lower extremity
0.001 0.984 0.015
I70.00 Atherosclerosis of aorta (without gangrene)
0.002 0.984 0.014
I87.2 Venous insufficiency (chronic) (peripheral)
0.000 0.984 0.016
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.984 0.016
I70.01 Atherosclerosis of aorta (with gangrene)
0.003 0.984 0.013
I30 Acute pericarditis
0.000 0.985 0.015
I49.0 Ventricular fibrillation and flutter
0.000 0.985 0.015
I70.81 Atherosclerosis of other arteries (with gangrene)
0.003 0.985 0.012
I70.80 Atherosclerosis of other arteries (without gangrene)
0.003 0.985 0.012
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.003 0.985 0.012
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.003 0.985 0.012
I80.8 Phlebitis and thrombophlebitis of other sites
0.000 0.985 0.015
I77.1 Stricture of artery
0.000 0.985 0.015
I52 Other heart disorders in diseases classified elsewhere
0.000 0.985 0.015
I48 Atrial fibrillation and flutter
0.000 0.985 0.015
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.985 0.015
I41 Myocarditis in diseases classified elsewhere
0.000 0.985 0.015
I40 Acute myocarditis
0.000 0.985 0.015
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.985 0.015
I32 Pericarditis in diseases classified elsewhere
0.000 0.985 0.015
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.001 0.985 0.014
I86 Varicose veins of other sites
0.000 0.985 0.015
I37.1 Pulmonary valve insufficiency
0.000 0.985 0.015
I36 Nonrheumatic tricuspid valve disorders
0.000 0.985 0.014
I70.11 Atherosclerosis of renal artery (with gangrene)
0.003 0.986 0.011
I34 Nonrheumatic mitral valve disorders
0.000 0.986 0.014
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.000 0.986 0.014
I46.9 Cardiac arrest, unspecified
0.000 0.986 0.014
I88.8 Other nonspecific lymphadenitis
0.000 0.986 0.014
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.986 0.014
I88.0 Nonspecific mesenteric lymphadenitis
0.000 0.986 0.014
I49.5 Sick sinus syndrome
0.000 0.986 0.014
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.986 0.013
I30.9 Acute pericarditis, unspecified
0.000 0.986 0.013
I63 Cerebral infarction
0.000 0.987 0.013
I49.4 Other and unspecified premature depolarisation
0.000 0.987 0.013
I70.10 Atherosclerosis of renal artery (without gangrene)
0.004 0.987 0.010
I77.5 Necrosis of artery
0.001 0.987 0.012
I77.4 Coeliac artery compression syndrome
0.001 0.987 0.012
I77.3 Arterial fibromuscular dysplasia
0.001 0.987 0.012
I77.2 Rupture of artery
0.001 0.987 0.012
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.001 0.987 0.013
I49.2 Junctional premature depolarisation
0.000 0.987 0.013
I87.9 Disorder of vein, unspecified
0.000 0.987 0.013
I87.0 Postphlebitic syndrome
0.000 0.987 0.013
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.987 0.013
I34.1 Mitral (valve) prolapse
0.000 0.987 0.013
I33.0 Acute and subacute infective endocarditis
0.000 0.987 0.013
I46.0 Cardiac arrest with successful resuscitation
0.000 0.987 0.013
I37.9 Pulmonary valve disorder, unspecified
0.000 0.987 0.012
I37.8 Other pulmonary valve disorders
0.000 0.987 0.012
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.987 0.012
I37.0 Pulmonary valve stenosis
0.000 0.987 0.012
I46.1 Sudden cardiac death, so described
0.000 0.988 0.012
I77.8 Other specified disorders of arteries and arterioles
0.001 0.988 0.011
I51 Complications and ill-defined descriptions of heart disease
0.000 0.988 0.012
I33.9 Acute endocarditis, unspecified
0.000 0.988 0.012
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.988 0.011
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.988 0.011
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.988 0.011
I30.8 Other forms of acute pericarditis
0.000 0.989 0.011
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.989 0.011
I49.3 Ventricular premature depolarisation
0.000 0.989 0.011
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.989 0.011
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.989 0.011
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.989 0.011
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.989 0.011
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.989 0.011
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.989 0.011
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.989 0.011
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.989 0.011
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.989 0.011
I40.9 Acute myocarditis, unspecified
0.000 0.989 0.011
I40.8 Other acute myocarditis
0.000 0.989 0.011
I40.1 Isolated myocarditis
0.000 0.989 0.011
I40.0 Infective myocarditis
0.000 0.989 0.011
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.989 0.011
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.989 0.011
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.989 0.011
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.989 0.011
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.989 0.011
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.989 0.011
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.989 0.011
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.989 0.011
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.989 0.011
I48.4 Atypical atrial flutter
0.000 0.989 0.011
I48.3 Typical atrial flutter
0.000 0.989 0.011
I48.2 Chronic atrial fibrillation
0.000 0.989 0.011
I48.1 Persistent atrial fibrillation
0.000 0.989 0.011
I48.0 Paroxysmal atrial fibrillation
0.000 0.989 0.011
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.989 0.011
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.989 0.011
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.989 0.011
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.989 0.011
I86.3 Vulval varices
0.000 0.989 0.011
I86.0 Sublingual varices
0.000 0.989 0.011
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.989 0.010
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.989 0.010
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.989 0.010
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.989 0.010
I77.9 Disorder of arteries and arterioles, unspecified
0.001 0.989 0.010
I77.0 Arteriovenous fistula, acquired
0.001 0.989 0.010
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.989 0.010
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.989 0.010
I51.9 Heart disease, unspecified
0.000 0.990 0.010
I86.8 Varicose veins of other specified sites
0.000 0.990 0.010
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.990 0.010
I89.1 Lymphangitis
0.000 0.990 0.010
I86.1 Scrotal varices
0.000 0.990 0.010
I47 Paroxysmal tachycardia
0.000 0.990 0.010
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.990 0.010
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.990 0.010
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.001 0.990 0.010
I86.2 Pelvic varices
0.000 0.990 0.010
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.990 0.010
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.990 0.010
I82 Other venous embolism and thrombosis
0.000 0.990 0.009
I87.8 Other specified disorders of veins
0.000 0.990 0.010
I49.1 Atrial premature depolarisation
0.000 0.990 0.010
I86.4 Gastric varices
0.000 0.990 0.010
I87.1 Compression of vein
0.000 0.991 0.009
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.991 0.009
I63.9 Cerebral infarction, unspecified
0.000 0.991 0.009
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.991 0.009
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.991 0.009
I51.0 Cardiac septal defect, acquired
0.000 0.991 0.009
I71.0 Dissection of aorta [any part]
0.000 0.991 0.008
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.991 0.008
I45 Other conduction disorders
0.000 0.991 0.009
I51.5 Myocardial degeneration
0.000 0.991 0.009
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.991 0.009
I51.4 Myocarditis, unspecified
0.000 0.991 0.009
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.991 0.008
I45.9 Conduction disorder, unspecified
0.000 0.991 0.009
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.992 0.008
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.992 0.008
I51.8 Other ill-defined heart diseases
0.000 0.992 0.008
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.992 0.008
I67.9 Cerebrovascular disease, unspecified
0.000 0.992 0.008
I30.1 Infective pericarditis
0.000 0.992 0.008
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.992 0.008
I73.9 Peripheral vascular disease, unspecified
0.000 0.992 0.008
I51.6 Cardiovascular disease, unspecified
0.000 0.992 0.008
I63.8 Other cerebral infarction
0.000 0.992 0.008
D86.9 Sarcoidosis, unspecified
0.008 0.992 0.000
I82.3 Embolism and thrombosis of renal vein
0.000 0.993 0.007
I82.1 Thrombophlebitis migrans
0.000 0.993 0.007
I82.0 Budd-Chiari syndrome
0.000 0.993 0.007
I47.0 Reentry ventricular arrhythmia
0.000 0.993 0.007
I49.8 Other specified cardiac arrhythmias
0.000 0.993 0.007
I45.4 Nonspecific intraventricular block
0.000 0.993 0.007
N41.1 Chronic prostatitis
0.000 0.993 0.007
N41.0 Acute prostatitis
0.000 0.993 0.007
I45.0 Right fascicular block
0.000 0.993 0.006
I82.2 Embolism and thrombosis of vena cava
0.001 0.994 0.006
I45.6 Preexcitation syndrome
0.000 0.994 0.006
I44 Atrioventricular and left bundle-branch block
0.000 0.994 0.006
C78.0 Secondary malignant neoplasm of lung
0.000 0.994 0.006
D86 Sarcoidosis
0.006 0.994 0.000
N41 Inflammatory diseases of prostate
0.000 0.994 0.006
I45.3 Trifascicular block
0.000 0.994 0.006
R40.2 Coma, unspecified
0.006 0.994 0.000
I82.9 Embolism and thrombosis of unspecified vein
0.001 0.994 0.005
G63.2 Diabetic polyneuropathy
0.000 0.994 0.006
I77.6 Arteritis, unspecified
0.003 0.994 0.003
I45.5 Other specified heart block
0.000 0.994 0.006
C78.2 Secondary malignant neoplasm of pleura
0.000 0.994 0.006

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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