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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs76450399
log Bayes Factor = 14.1937
Chromosome 12   position 9,143,781  (GRCh37) Explore rs76450399 on Ensembl!
Variant rs76450399 is part of Cluster X0087

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
Chapter I Certain infectious and parasitic diseases
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
Chapter II Neoplasms
0.997 0.003 0.000
K70-K77 Diseases of liver
0.997 0.003 0.000
B95-B98 Bacterial, viral and other infectious agents
0.994 0.006 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.992 0.008 0.000
Chapter XX External causes of morbidity and mortality
0.989 0.011 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.989 0.011 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.983 0.017 0.000
C15-C26 Malignant neoplasms of digestive organs
0.981 0.019 0.000
C18 Malignant neoplasm of colon
0.965 0.035 0.000
K21 Gastro-oesophageal reflux disease
0.963 0.037 0.000
K70 Alcoholic liver disease
0.963 0.037 0.000
M20-M25 Other joint disorders
0.954 0.046 0.000
M45-M49 Spondylopathies
0.953 0.047 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.952 0.048 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.952 0.048 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.946 0.054 0.000
M80-M85 Disorders of bone density and structure
0.941 0.059 0.000
K21.0 Gastro-oesophageal reflux disease with oesophagitis
0.939 0.061 0.000
K65-K67 Diseases of peritoneum
0.926 0.074 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.926 0.074 0.000
Chapter V Mental and behavioural disorders
0.923 0.077 0.000
K74 Fibrosis and cirrhosis of liver
0.919 0.081 0.000
C44 Other malignant neoplasms of skin
0.914 0.086 0.000
D00-D09 In situ neoplasms
0.907 0.093 0.000
V10-V19 Pedal cyclist injured in transport accident
0.906 0.094 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.903 0.097 0.000
M48 Other spondylopathies
0.902 0.098 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.900 0.100 0.000
K31 Other diseases of stomach and duodenum
0.899 0.101 0.000
R05 Cough
0.899 0.101 0.000
R94 Abnormal results of function studies
0.898 0.102 0.000
S20-S29 Injuries to the thorax
0.898 0.102 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.891 0.109 0.000
K66 Other disorders of peritoneum
0.890 0.110 0.000
C18.7 Sigmoid colon
0.890 0.110 0.000
R94.5 Abnormal results of liver function studies
0.886 0.114 0.000
K70.9 Alcoholic liver disease, unspecified
0.884 0.116 0.000
A30-A49 Other bacterial diseases
0.883 0.117 0.000
S80-S89 Injuries to the knee and lower leg
0.881 0.119 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.881 0.119 0.000
Chapter VI Diseases of the nervous system
0.879 0.121 0.000
C18.9 Colon, unspecified
0.877 0.123 0.000
R00 Abnormalities of heart beat
0.876 0.124 0.000
K76 Other diseases of liver
0.876 0.124 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.871 0.129 0.000
R06 Abnormalities of breathing
0.868 0.132 0.000
K35-K38 Diseases of appendix
0.868 0.132 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.865 0.135 0.000
M48.0 Spinal stenosis
0.865 0.135 0.000
T81 Complications of procedures, not elsewhere classified
0.864 0.136 0.000
K66.0 Peritoneal adhesions
0.864 0.136 0.000
M21 Other acquired deformities of limbs
0.863 0.137 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.856 0.144 0.000
K70.3 Alcoholic cirrhosis of liver
0.855 0.145 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.855 0.145 0.000
K75 Other inflammatory liver diseases
0.853 0.147 0.000
M20 Acquired deformities of fingers and toes
0.853 0.147 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.850 0.150 0.000
Chapter IX Diseases of the circulatory system
0.849 0.151 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.847 0.153 0.000
M48.06 Spinal stenosis (Lumbar region)
0.846 0.154 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.846 0.154 0.000
K29 Gastritis and duodenitis
0.845 0.155 0.000
R00.2 Palpitations
0.842 0.158 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.837 0.163 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.837 0.163 0.000
K31.8 Other specified diseases of stomach and duodenum
0.836 0.164 0.000
Chapter VIII Diseases of the ear and mastoid process
0.833 0.167 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.830 0.170 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.829 0.171 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.829 0.171 0.000
M65-M68 Disorders of synovium and tendon
0.829 0.171 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.828 0.172 0.000
K90-K93 Other diseases of the digestive system
0.825 0.175 0.000
C44.0 Skin of lip
0.824 0.176 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.824 0.176 0.000
B35-B49 Mycoses
0.824 0.176 0.000
K50-K52 Noninfective enteritis and colitis
0.824 0.176 0.000
F30-F39 Mood [affective] disorders
0.822 0.178 0.000
K22 Other diseases of oesophagus
0.820 0.180 0.000
K74.6 Other and unspecified cirrhosis of liver
0.819 0.181 0.000
M84 Disorders of continuity of bone
0.816 0.184 0.000
M50-M54 Other dorsopathies
0.815 0.185 0.000
M85 Other disorders of bone density and structure
0.814 0.186 0.000
M40-M43 Deforming dorsopathies
0.813 0.187 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.811 0.189 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.811 0.189 0.000
A41 Other septicaemia
0.808 0.192 0.000
K35 Acute appendicitis
0.806 0.194 0.000
A00-A09 Intestinal infectious diseases
0.805 0.195 0.000
K76.6 Portal hypertension
0.805 0.195 0.000
E10-E14 Diabetes mellitus
0.804 0.196 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.804 0.196 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.804 0.196 0.000
V18.0 Driver injured in nontraffic accident
0.803 0.197 0.000
S82 Fracture of lower leg, including ankle
0.801 0.199 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.796 0.204 0.000
W50-W64 Exposure to animate mechanical forces
0.793 0.207 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.791 0.209 0.000
Chapter XXII Codes for special purposes
0.790 0.210 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.790 0.210 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.789 0.211 0.000
M70-M79 Other soft tissue disorders
0.787 0.213 0.000
S40-S49 Injuries to the shoulder and upper arm
0.786 0.213 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.786 0.214 0.000
M31 Other necrotising vasculopathies
0.785 0.215 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.785 0.215 0.000
E70-E90 Metabolic disorders
0.784 0.216 0.000
C18.4 Transverse colon
0.783 0.217 0.000
K82 Other diseases of gallbladder
0.783 0.217 0.000
K86 Other diseases of pancreas
0.782 0.218 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.780 0.219 0.000
I85 Oesophageal varices
0.777 0.223 0.000
C18.6 Descending colon
0.777 0.223 0.000
M21.3 Wrist or foot drop (acquired)
0.777 0.223 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.776 0.224 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.775 0.224 0.000
S90-S99 Injuries to the ankle and foot
0.773 0.227 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.772 0.228 0.000
D06 Carcinoma in situ of cervix uteri
0.768 0.232 0.000
S50-S59 Injuries to the elbow and forearm
0.768 0.232 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.767 0.233 0.000
K85 Acute pancreatitis
0.767 0.233 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.765 0.235 0.000
R06.8 Other and unspecified abnormalities of breathing
0.765 0.235 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.765 0.235 0.000
F45 Somatoform disorders
0.764 0.236 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.764 0.236 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.762 0.238 0.000
C44.2 Skin of ear and external auricular canal
0.761 0.239 0.000
K21.9 Gastro-oesophageal reflux disease without oesophagitis
0.759 0.241 0.000
M86-M90 Other osteopathies
0.759 0.241 0.000
C44.4 Skin of scalp and neck
0.758 0.242 0.000
C78.7 Secondary malignant neoplasm of liver
0.758 0.242 0.000
F60-F69 Disorders of adult personality and behaviour
0.758 0.242 0.000
S70-S79 Injuries to the hip and thigh
0.757 0.243 0.000
S60-S69 Injuries to the wrist and hand
0.757 0.243 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.756 0.244 0.000
R06.4 Hyperventilation
0.756 0.244 0.000
X60-X84 Intentional self-harm
0.755 0.244 0.000
M47 Spondylosis
0.755 0.245 0.000
K31.1 Adult hypertrophic pyloric stenosis
0.754 0.246 0.000
M24 Other specific joint derangements
0.753 0.246 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.753 0.247 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.753 0.247 0.000
K70.4 Alcoholic hepatic failure
0.751 0.249 0.000
M20.5 Other deformities of toe(s) (acquired)
0.749 0.251 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.749 0.251 0.000
V20-V29 Motorcycle rider injured in transport accident
0.748 0.252 0.000
K75.8 Other specified inflammatory liver diseases
0.748 0.252 0.000
C44.7 Skin of lower limb, including hip
0.747 0.253 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.747 0.253 0.000
A41.9 Septicaemia, unspecified
0.746 0.254 0.000
K26 Duodenal ulcer
0.746 0.254 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.744 0.256 0.000
F32 Depressive episode
0.742 0.258 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.741 0.259 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.740 0.260 0.000
C50-C50 Malignant neoplasm of breast
0.740 0.260 0.000
K20 Oesophagitis
0.739 0.261 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.738 0.262 0.000
K74.0 Hepatic fibrosis
0.737 0.263 0.000
M23 Internal derangement of knee
0.734 0.266 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.734 0.266 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.734 0.266 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.734 0.266 0.000
Y40 Systemic antibiotics
0.733 0.267 0.000
E10 Insulin-dependent diabetes mellitus
0.733 0.267 0.000
K72 Hepatic failure, not elsewhere classified
0.732 0.267 0.000
R42 Dizziness and giddiness
0.732 0.268 0.000
I20-I25 Ischaemic heart diseases
0.729 0.271 0.000
C16 Malignant neoplasm of stomach
0.728 0.271 0.000
M20.1 Hallux valgus (acquired)
0.728 0.272 0.000
B07 Viral warts
0.727 0.273 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.726 0.274 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.725 0.275 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.725 0.275 0.000
S27 Injury of other and unspecified intrathoracic organs
0.724 0.276 0.000
M46 Other inflammatory spondylopathies
0.724 0.276 0.000
M85.8 Other specified disorders of bone density and structure
0.723 0.277 0.000
K35.0 Acute appendicitis with generalised peritonitis
0.721 0.279 0.000
C43 Malignant melanoma of skin
0.721 0.279 0.000
E20-E35 Disorders of other endocrine glands
0.720 0.279 0.000
K29.6 Other gastritis
0.720 0.280 0.000
B15-B19 Viral hepatitis
0.720 0.280 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.720 0.280 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.718 0.282 0.000
I85.0 Oesophageal varices with bleeding
0.718 0.282 0.000
M81 Osteoporosis without pathological fracture
0.718 0.282 0.000
R80 Isolated proteinuria
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
D03 Melanoma in situ
0.717 0.283 0.000
R06.0 Dyspnoea
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
B99-B99 Other infectious diseases
0.716 0.283 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.716 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.716 0.283 0.000
B65-B83 Helminthiases
0.716 0.283 0.000
B50-B64 Protozoal diseases
0.716 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.716 0.283 0.000
A80-A89 Viral infections of the central nervous system
0.716 0.283 0.000
A75-A79 Rickettsioses
0.716 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.716 0.283 0.000
A65-A69 Other spirochaetal diseases
0.716 0.283 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.716 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.716 0.283 0.000
A15-A19 Tuberculosis
0.716 0.283 0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)
0.715 0.284 0.000
T79-T79 Certain early complications of trauma
0.715 0.285 0.000
T33-T35 Frostbite
0.715 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.285 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.715 0.285 0.000
T00-T07 Injuries involving multiple body regions
0.715 0.285 0.000
S10-S19 Injuries to the neck
0.715 0.285 0.000
M65 Synovitis and tenosynovitis
0.715 0.285 0.000
M80 Osteoporosis with pathological fracture
0.715 0.285 0.000
I83 Varicose veins of lower extremities
0.715 0.285 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.715 0.285 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.715 0.285 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.715 0.285 0.000
K77 Liver disorders in diseases classified elsewhere
0.715 0.285 0.000
K73 Chronic hepatitis, not elsewhere classified
0.715 0.285 0.000
K71 Toxic liver disease
0.715 0.285 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.714 0.286 0.000
D05 Carcinoma in situ of breast
0.714 0.286 0.000
C20 Malignant neoplasm of rectum
0.714 0.286 0.000
K74.3 Primary biliary cirrhosis
0.712 0.288 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.712 0.288 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.711 0.289 0.000
A41.8 Other specified septicaemia
0.710 0.290 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.710 0.290 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.710 0.290 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.709 0.290 0.000
M43 Other deforming dorsopathies
0.709 0.291 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.709 0.291 0.000
Y35-Y36 Legal intervention and operations of war
0.709 0.291 0.000
Y10-Y34 Event of undetermined intent
0.709 0.291 0.000
Y00-Y09 Assault
0.709 0.291 0.000
X85-X99 Assault
0.709 0.291 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.709 0.291 0.000
X50-X57 Overexertion, travel and privation
0.709 0.291 0.000
X30-X39 Exposure to forces of nature
0.709 0.291 0.000
X20-X29 Contact with venomous animals and plants
0.709 0.291 0.000
X10-X19 Contact with heat and hot substances
0.709 0.291 0.000
X00-X09 Exposure to smoke, fire and flames
0.709 0.291 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.709 0.291 0.000
W75-W84 Other accidental threats to breathing
0.709 0.291 0.000
W65-W74 Accidental drowning and submersion
0.709 0.291 0.000
V98-V99 Other and unspecified transport accidents
0.709 0.291 0.000
V95-V97 Air and space transport accidents
0.709 0.291 0.000
V90-V94 Water transport accidents
0.709 0.291 0.000
V80-V89 Other land transport accidents
0.709 0.291 0.000
V70-V79 Bus occupant injured in transport accident
0.709 0.291 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.709 0.291 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.709 0.291 0.000
V40-V49 Car occupant injured in transport accident
0.709 0.291 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.709 0.291 0.000
V01-V09 Pedestrian injured in transport accident
0.709 0.291 0.000
K28 Gastrojejunal ulcer
0.709 0.291 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.709 0.291 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.709 0.291 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.708 0.292 0.000
K52 Other non-infective gastro-enteritis and colitis
0.706 0.294 0.000
F43 Reaction to severe stress, and adjustment disorders
0.705 0.295 0.000
W00-W19 Falls
0.705 0.295 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.705 0.295 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.705 0.295 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.705 0.295 0.000
C18.2 Ascending colon
0.704 0.295 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.704 0.296 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.703 0.297 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.703 0.297 0.000
C21 Malignant neoplasm of anus and anal canal
0.703 0.297 0.000
C17 Malignant neoplasm of small intestine
0.703 0.297 0.000
C23 Malignant neoplasm of gallbladder
0.703 0.297 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.703 0.297 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.703 0.297 0.000
F45.8 Other somatoform disorders
0.703 0.297 0.000
M20.3 Other deformity of hallux (acquired)
0.703 0.297 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.702 0.298 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.701 0.299 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.701 0.299 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.696 0.304 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.695 0.305 0.000
B02 Zoster [herpes zoster]
0.694 0.306 0.000
M23.3 Other meniscus derangements
0.694 0.306 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.693 0.307 0.000
K76.8 Other specified diseases of liver
0.693 0.307 0.000
M54 Dorsalgia
0.693 0.307 0.000
D04 Carcinoma in situ of skin
0.692 0.307 0.000
T66-T78 Other and unspecified effects of external causes
0.692 0.308 0.000
C18.8 Overlapping lesion of colon
0.692 0.308 0.000
C18.5 Splenic flexure
0.692 0.308 0.000
C18.3 Hepatic flexure
0.692 0.308 0.000
C18.1 Appendix
0.692 0.308 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.690 0.309 0.000
K70.1 Alcoholic hepatitis
0.690 0.309 0.000
K70.0 Alcoholic fatty liver
0.690 0.309 0.000
R30-R39 Symptoms and signs involving the urinary system
0.690 0.310 0.000
I85.9 Oesophageal varices without bleeding
0.687 0.313 0.000
K83 Other diseases of biliary tract
0.686 0.314 0.000
B37 Candidiasis
0.686 0.314 0.000
S82.1 Fracture of upper end of tibia
0.686 0.314 0.000
S20 Superficial injury of thorax
0.685 0.314 0.000
F99-F99 Unspecified mental disorder
0.684 0.316 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.684 0.316 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.684 0.316 0.000
M34 Systemic sclerosis
0.684 0.316 0.000
M33 Dermatopolymyositis
0.684 0.316 0.000
M32 Systemic lupus erythematosus
0.684 0.316 0.000
M30 Polyarteritis nodosa and related conditions
0.684 0.316 0.000
L85 Other epidermal thickening
0.684 0.316 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.683 0.317 0.000
M49 Spondylopathies in diseases classified elsewhere
0.683 0.317 0.000
K22.2 Oesophageal obstruction
0.682 0.318 0.000
M21.1 Varus deformity, not elsewhere classified
0.680 0.320 0.000
K29.7 Gastritis, unspecified
0.679 0.321 0.000
C44.1 Skin of eyelid, including canthus
0.676 0.324 0.000
C18.0 Caecum
0.676 0.324 0.000
E14 Unspecified diabetes mellitus
0.675 0.325 0.000
M83 Adult osteomalacia
0.674 0.325 0.000
M82 Osteoporosis in diseases classified elsewhere
0.674 0.325 0.000
T90 Sequelae of injuries of head
0.672 0.328 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.671 0.328 0.000
T93 Sequelae of injuries of lower limb
0.671 0.329 0.000
R18 Ascites
0.671 0.329 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.671 0.329 0.000
K82.8 Other specified diseases of gallbladder
0.670 0.330 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.670 0.330 0.000
D06.9 Cervix, unspecified
0.669 0.331 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.668 0.331 0.000
M45 Ankylosing spondylitis
0.667 0.333 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.666 0.333 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.666 0.334 0.000
T14 Injury of unspecified body region
0.665 0.335 0.000
W20-W49 Exposure to inanimate mechanical forces
0.665 0.335 0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere
0.664 0.336 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.664 0.336 0.000
K29.4 Chronic atrophic gastritis
0.663 0.337 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.662 0.338 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.662 0.338 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.662 0.338 0.000
F80-F89 Disorders of psychological development
0.662 0.338 0.000
F70-F79 Mental retardation
0.662 0.338 0.000
S80 Superficial injury of lower leg
0.662 0.338 0.000
Y83.8 Other surgical procedures
0.661 0.339 0.000
K31.9 Disease of stomach and duodenum, unspecified
0.661 0.339 0.000
T86 Failure and rejection of transplanted organs and tissues
0.661 0.339 0.000
I21 Acute myocardial infarction
0.660 0.340 0.000
S82.2 Fracture of shaft of tibia
0.660 0.340 0.000
T91 Sequelae of injuries of neck and trunk
0.660 0.340 0.000
K74.5 Biliary cirrhosis, unspecified
0.659 0.341 0.000
K74.4 Secondary biliary cirrhosis
0.659 0.341 0.000
K74.2 Hepatic fibrosis with hepatic sclerosis
0.659 0.341 0.000
K74.1 Hepatic sclerosis
0.659 0.341 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.659 0.341 0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)
0.658 0.342 0.000
S82.3 Fracture of lower end of tibia
0.658 0.342 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.657 0.343 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.657 0.343 0.000
I81 Portal vein thrombosis
0.657 0.343 0.000
K29.2 Alcoholic gastritis
0.657 0.343 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.655 0.345 0.000
C44.8 Overlapping lesion of skin
0.655 0.345 0.000
K27 Peptic ulcer, site unspecified
0.655 0.345 0.000
K22.4 Dyskinesia of oesophagus
0.655 0.345 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.654 0.346 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.654 0.346 0.000
C25 Malignant neoplasm of pancreas
0.654 0.346 0.000
K25 Gastric ulcer
0.653 0.346 0.000
I60-I69 Cerebrovascular diseases
0.653 0.347 0.000
S64 Injury of nerves at wrist and hand level
0.653 0.347 0.000
G62 Other polyneuropathies
0.653 0.347 0.000
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods
0.653 0.347 0.000
R41.0 Disorientation, unspecified
0.652 0.348 0.000
K35.1 Acute appendicitis with peritoneal abscess
0.651 0.349 0.000
Y57 Other and unspecified drugs and medicaments
0.651 0.349 0.000
Y83.6 Removal of other organ (partial) (total)
0.651 0.349 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.651 0.349 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.650 0.349 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.650 0.349 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.650 0.349 0.000
K29.1 Other acute gastritis
0.650 0.350 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.650 0.350 0.000
G70-G73 Diseases of myoneural junction and muscle
0.649 0.351 0.000
V19 Pedal cyclist injured in other and unspecified transport accidents
0.649 0.351 0.000
V17 Pedal cyclist injured in collision with fixed or stationary object
0.649 0.351 0.000
V16 Pedal cyclist injured in collision with other nonmotor vehicle
0.649 0.351 0.000
V15 Pedal cyclist injured in collision with railway train or railway vehicle
0.649 0.351 0.000
V14 Pedal cyclist injured in collision with heavy transport vehicle or bus
0.649 0.351 0.000
V13 Pedal cyclist injured in collision with car, pick-up truck or van
0.649 0.351 0.000
V12 Pedal cyclist injured in collision with two- or three-wheeled motor vehicle
0.649 0.351 0.000
V11 Pedal cyclist injured in collision with other pedal cycle
0.649 0.351 0.000
V10 Pedal cyclist injured in collision with pedestrian or animal
0.649 0.351 0.000
S82.5 Fracture of medial malleolus
0.649 0.351 0.000
C44.5 Skin of trunk
0.648 0.352 0.000
R45 Symptoms and signs involving emotional state
0.648 0.352 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.648 0.352 0.000
T87 Complications peculiar to reattachment and amputation
0.647 0.353 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.647 0.353 0.000
H65-H75 Diseases of middle ear and mastoid
0.647 0.353 0.000
E86 Volume depletion
0.647 0.353 0.000
M48.9 Spondylopathy, unspecified
0.646 0.354 0.000
M48.8 Other specified spondylopathies
0.646 0.354 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.646 0.354 0.000
M48.4 Fatigue fracture of vertebra
0.646 0.354 0.000
M48.3 Traumatic spondylopathy
0.646 0.354 0.000
M48.2 Kissing spine
0.646 0.354 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.646 0.354 0.000
L20-L30 Dermatitis and eczema
0.646 0.354 0.000
L50-L54 Urticaria and erythema
0.646 0.354 0.000
C44.3 Skin of other and unspecified parts of face
0.646 0.354 0.000
E40-E46 Malnutrition
0.645 0.354 0.000
K85.9 Acute pancreatitis, unspecified
0.645 0.355 0.000
K31.6 Fistula of stomach and duodenum
0.645 0.355 0.000
K31.5 Obstruction of duodenum
0.645 0.355 0.000
K31.4 Gastric diverticulum
0.645 0.355 0.000
K31.3 Pylorospasm, not elsewhere classified
0.645 0.355 0.000
K31.2 Hourglass stricture and stenosis of stomach
0.645 0.355 0.000
K31.0 Acute dilatation of stomach
0.645 0.355 0.000
E65-E68 Obesity and other hyperalimentation
0.644 0.355 0.000
R94.8 Abnormal results of function studies of other organs and systems
0.644 0.356 0.000
R94.7 Abnormal results of other endocrine function studies
0.644 0.356 0.000
R94.6 Abnormal results of thyroid function studies
0.644 0.356 0.000
R94.4 Abnormal results of kidney function studies
0.644 0.356 0.000
R94.2 Abnormal results of pulmonary function studies
0.644 0.356 0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses
0.644 0.356 0.000
R94.0 Abnormal results of function studies of central nervous system
0.644 0.356 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.644 0.356 0.000
K82.4 Cholesterolosis of gallbladder
0.644 0.356 0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.644 0.356 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.644 0.356 0.000
M50 Cervical disk disorders
0.644 0.356 0.000
S29 Other and unspecified injuries of thorax
0.644 0.356 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.644 0.356 0.000
S26 Injury of heart
0.644 0.356 0.000
S25 Injury of blood vessels of thorax
0.644 0.356 0.000
S24 Injury of nerves and spinal cord at thorax level
0.644 0.356 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.644 0.356 0.000
S21 Open wound of thorax
0.644 0.356 0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)
0.643 0.357 0.000
R04 Haemorrhage from respiratory passages
0.643 0.357 0.000
I24 Other acute ischaemic heart diseases
0.643 0.357 0.000
K38 Other diseases of appendix
0.641 0.359 0.000
I86 Varicose veins of other sites
0.641 0.359 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.641 0.359 0.000
Y40.0 Penicillins
0.641 0.359 0.000
S22.4 Multiple fractures of ribs
0.641 0.359 0.000
K86.9 Disease of pancreas, unspecified
0.640 0.360 0.000
E10.9 Without complications
0.640 0.360 0.000
F60 Specific personality disorders
0.639 0.361 0.000
E88 Other metabolic disorders
0.639 0.361 0.000
L89 Decubitus ulcer
0.639 0.361 0.000
R46 Symptoms and signs involving appearance and behaviour
0.638 0.361 0.000
R43 Disturbances of smell and taste
0.638 0.361 0.000
K66.9 Disorder of peritoneum, unspecified
0.638 0.362 0.000
K66.8 Other specified disorders of peritoneum
0.638 0.362 0.000
K66.1 Haemoperitoneum
0.638 0.362 0.000
D48.5 Skin
0.638 0.362 0.000
M22 Disorders of patella
0.637 0.363 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.636 0.364 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.635 0.365 0.000
G30-G32 Other degenerative diseases of the nervous system
0.635 0.365 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.635 0.365 0.000
M43.1 Spondylolisthesis
0.635 0.365 0.000
H90-H95 Other disorders of ear
0.634 0.366 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.634 0.366 0.000
A48 Other bacterial diseases, not elsewhere classified
0.633 0.367 0.000
A44 Bartonellosis
0.633 0.367 0.000
A43 Nocardiosis
0.633 0.367 0.000
A42 Actinomycosis
0.633 0.367 0.000
A40 Streptococcal septicaemia
0.633 0.367 0.000
A39 Meningococcal infection
0.633 0.367 0.000
A37 Whooping cough
0.633 0.367 0.000
A36 Diphtheria
0.633 0.367 0.000
A32 Listeriosis
0.633 0.367 0.000
A31 Infection due to other mycobacteria
0.633 0.367 0.000
A30 Leprosy [Hansen's disease]
0.633 0.367 0.000
A46 Erysipelas
0.633 0.367 0.000
A38 Scarlet fever
0.633 0.367 0.000
A35 Other tetanus
0.633 0.367 0.000
A34 Obstetrical tetanus
0.633 0.367 0.000
A33 Tetanus neonatorum
0.633 0.367 0.000
H60-H62 Diseases of external ear
0.633 0.367 0.000
K35.9 Acute appendicitis, unspecified
0.633 0.367 0.000
T92 Sequelae of injuries of upper limb
0.633 0.367 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.632 0.367 0.000
S89 Other and unspecified injuries of lower leg
0.632 0.368 0.000
S88 Traumatic amputation of lower leg
0.632 0.368 0.000
S87 Crushing injury of lower leg
0.632 0.368 0.000
S86 Injury of muscle and tendon at lower leg level
0.632 0.368 0.000
S85 Injury of blood vessels at lower leg level
0.632 0.368 0.000
S84 Injury of nerves at lower leg level
0.632 0.368 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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