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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7653911
log Bayes Factor = 27.7327
Chromosome 4   position 33,655,673  (GRCh37) Explore rs7653911 on Ensembl!
Variant rs7653911 is part of Cluster X0277

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.997 0.003 0.000
I50 Heart failure
0.996 0.004 0.000
S00-S09 Injuries to the head
0.996 0.004 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.996 0.004 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.995 0.005 0.000
E70-E90 Metabolic disorders
0.994 0.006 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.993 0.007 0.000
Chapter V Mental and behavioural disorders
0.993 0.007 0.000
K02 Dental caries
0.992 0.008 0.000
K55-K64 Other diseases of intestines
0.991 0.009 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.991 0.009 0.000
K02.9 Dental caries, unspecified
0.990 0.010 0.000
I25.2 Old myocardial infarction
0.985 0.015 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.981 0.019 0.000
I20 Angina pectoris
0.980 0.020 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.978 0.022 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.977 0.023 0.000
K63 Other diseases of intestine
0.974 0.026 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.970 0.030 0.000
I50.0 Congestive heart failure
0.970 0.030 0.000
K90-K93 Other diseases of the digestive system
0.968 0.032 0.000
I46 Cardiac arrest
0.967 0.033 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.962 0.038 0.000
K63.5 Polyp of colon
0.961 0.039 0.000
I24 Other acute ischaemic heart diseases
0.960 0.040 0.000
E78.0 Pure hypercholesterolaemia
0.959 0.041 0.000
I20.0 Unstable angina
0.958 0.042 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.958 0.042 0.000
S01 Open wound of head
0.956 0.044 0.000
S00 Superficial injury of head
0.953 0.047 0.000
Chapter VI Diseases of the nervous system
0.953 0.047 0.000
K50-K52 Noninfective enteritis and colitis
0.951 0.049 0.000
I50.1 Left ventricular failure
0.951 0.049 0.000
K86 Other diseases of pancreas
0.946 0.054 0.000
K92 Other diseases of digestive system
0.944 0.056 0.000
E10-E14 Diabetes mellitus
0.942 0.058 0.000
E87.5 Hyperkalaemia
0.937 0.063 0.000
M20-M25 Other joint disorders
0.929 0.071 0.000
Chapter XX External causes of morbidity and mortality
0.929 0.071 0.000
Chapter VII Diseases of the eye and adnexa
0.924 0.076 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.922 0.078 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.919 0.081 0.000
I46.0 Cardiac arrest with successful resuscitation
0.916 0.084 0.000
K35-K38 Diseases of appendix
0.915 0.085 0.000
M45-M49 Spondylopathies
0.914 0.086 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.912 0.088 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.906 0.094 0.000
I21 Acute myocardial infarction
0.903 0.097 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.896 0.103 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.895 0.105 0.000
K57 Diverticular disease of intestine
0.894 0.106 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.892 0.108 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.891 0.109 0.000
E00-E07 Disorders of thyroid gland
0.890 0.110 0.000
M23 Internal derangement of knee
0.890 0.110 0.000
F30-F39 Mood [affective] disorders
0.888 0.112 0.000
I34 Nonrheumatic mitral valve disorders
0.887 0.113 0.000
I45 Other conduction disorders
0.884 0.116 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.884 0.116 0.000
E20-E35 Disorders of other endocrine glands
0.876 0.123 0.000
I49 Other cardiac arrhythmias
0.875 0.125 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.872 0.128 0.000
R29.6 Tendency to fall, not elsewhere classified
0.872 0.128 0.000
Chapter I Certain infectious and parasitic diseases
0.872 0.128 0.000
I22 Subsequent myocardial infarction
0.870 0.130 0.000
K92.1 Melaena
0.868 0.132 0.000
M70-M79 Other soft tissue disorders
0.864 0.136 0.000
Chapter XIV Diseases of the genitourinary system
0.864 0.136 0.000
T39.1 4-Aminophenol derivatives
0.863 0.137 0.000
R01 Cardiac murmurs and other cardiac sounds
0.862 0.138 0.000
I20.8 Other forms of angina pectoris
0.860 0.140 0.000
K51 Ulcerative colitis
0.859 0.141 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.859 0.141 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.857 0.143 0.000
K83 Other diseases of biliary tract
0.855 0.145 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.852 0.148 0.000
R03.1 Nonspecific low blood-pressure reading
0.850 0.150 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.850 0.150 0.000
R07 Pain in throat and chest
0.849 0.151 0.000
N17-N19 Renal failure
0.846 0.154 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.845 0.155 0.000
I25.5 Ischaemic cardiomyopathy
0.844 0.156 0.000
K92.9 Disease of digestive system, unspecified
0.844 0.156 0.000
S60-S69 Injuries to the wrist and hand
0.844 0.156 0.000
S40-S49 Injuries to the shoulder and upper arm
0.843 0.157 0.000
T42.4 Benzodiazepines
0.843 0.157 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.842 0.158 0.000
I46.9 Cardiac arrest, unspecified
0.842 0.158 0.000
K50 Crohn's disease [regional enteritis]
0.841 0.159 0.000
R50-R69 General symptoms and signs
0.840 0.160 0.000
R00 Abnormalities of heart beat
0.839 0.161 0.000
I05-I09 Chronic rheumatic heart diseases
0.838 0.162 0.000
E87.2 Acidosis
0.838 0.162 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.837 0.163 0.000
M47 Spondylosis
0.837 0.163 0.000
I50.9 Heart failure, unspecified
0.836 0.164 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.836 0.164 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.836 0.164 0.000
I24.8 Other forms of acute ischaemic heart disease
0.836 0.164 0.000
I60-I69 Cerebrovascular diseases
0.836 0.164 0.000
E14 Unspecified diabetes mellitus
0.835 0.165 0.000
S01.8 Open wound of other parts of head
0.834 0.166 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.833 0.167 0.000
S00.9 Superficial injury of head, part unspecified
0.832 0.168 0.000
K85 Acute pancreatitis
0.832 0.168 0.000
K86.8 Other specified diseases of pancreas
0.831 0.169 0.000
K57.2 Diverticular disease of large intestine with perforation and abscess
0.830 0.170 0.000
N18 Chronic renal failure
0.829 0.171 0.000
F10.2 Dependence syndrome
0.826 0.174 0.000
K55 Vascular disorders of intestine
0.824 0.176 0.000
K37 Unspecified appendicitis
0.822 0.178 0.000
M25 Other joint disorders, not elsewhere classified
0.820 0.180 0.000
S01.9 Open wound of head, part unspecified
0.818 0.182 0.000
Chapter VIII Diseases of the ear and mastoid process
0.817 0.183 0.000
S06 Intracranial injury
0.817 0.183 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.816 0.184 0.000
F10.3 Withdrawal state
0.816 0.184 0.000
I38 Endocarditis, valve unspecified
0.815 0.185 0.000
M60-M63 Disorders of muscles
0.814 0.186 0.000
S00.7 Multiple superficial injuries of head
0.814 0.186 0.000
H25-H28 Disorders of lens
0.813 0.187 0.000
K86.0 Alcohol-induced chronic pancreatitis
0.813 0.187 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.812 0.188 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.810 0.190 0.000
R07.2 Precordial pain
0.809 0.191 0.000
E87.7 Fluid overload
0.808 0.192 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.807 0.193 0.000
R47-R49 Symptoms and signs involving speech and voice
0.806 0.194 0.000
K56.6 Other and unspecified intestinal obstruction
0.804 0.196 0.000
T66-T78 Other and unspecified effects of external causes
0.802 0.198 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.802 0.198 0.000
K70-K77 Diseases of liver
0.800 0.200 0.000
Chapter XXII Codes for special purposes
0.799 0.201 0.000
I25.3 Aneurysm of heart
0.796 0.204 0.000
E78.5 Hyperlipidaemia, unspecified
0.795 0.205 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.795 0.205 0.000
S00.0 Superficial injury of scalp
0.794 0.206 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.792 0.208 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.792 0.208 0.000
S70-S79 Injuries to the hip and thigh
0.790 0.210 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.789 0.211 0.000
A30-A49 Other bacterial diseases
0.789 0.211 0.000
S09 Other and unspecified injuries of head
0.788 0.212 0.000
F60-F69 Disorders of adult personality and behaviour
0.788 0.212 0.000
M23.3 Other meniscus derangements
0.788 0.212 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.786 0.214 0.000
K51.9 Ulcerative colitis, unspecified
0.785 0.215 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.782 0.218 0.000
K86.1 Other chronic pancreatitis
0.780 0.220 0.000
G90-G99 Other disorders of the nervous system
0.780 0.220 0.000
K08 Other disorders of teeth and supporting structures
0.780 0.220 0.000
R01.1 Cardiac murmur, unspecified
0.779 0.221 0.000
K13 Other diseases of lip and oral mucosa
0.778 0.221 0.000
E10 Insulin-dependent diabetes mellitus
0.777 0.223 0.000
N18.9 Chronic renal failure, unspecified
0.777 0.223 0.000
F17.2 Dependence syndrome
0.776 0.224 0.000
R13 Dysphagia
0.775 0.225 0.000
H25 Senile cataract
0.775 0.225 0.000
I51 Complications and ill-defined descriptions of heart disease
0.774 0.226 0.000
K04 Diseases of pulp and periapical tissues
0.774 0.226 0.000
I63 Cerebral infarction
0.772 0.228 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.770 0.230 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.770 0.230 0.000
I34.0 Mitral (valve) insufficiency
0.770 0.230 0.000
M05-M14 Inflammatory polyarthropathies
0.769 0.231 0.000
K07 Dentofacial anomalies [including malocclusion]
0.768 0.232 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.767 0.233 0.000
E11 Non-insulin-dependent diabetes mellitus
0.766 0.234 0.000
F32 Depressive episode
0.766 0.234 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.766 0.234 0.000
M77 Other enthesopathies
0.764 0.236 0.000
R02 Gangrene, not elsewhere classified
0.763 0.237 0.000
K12 Stomatitis and related lesions
0.763 0.237 0.000
M80-M85 Disorders of bone density and structure
0.763 0.237 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.762 0.238 0.000
W00-W19 Falls
0.761 0.239 0.000
S01.1 Open wound of eyelid and periocular area
0.760 0.240 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.760 0.240 0.000
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess
0.760 0.240 0.000
N17 Acute renal failure
0.758 0.242 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.757 0.243 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.756 0.244 0.000
F40 Phobic anxiety disorders
0.756 0.244 0.000
K58 Irritable bowel syndrome
0.756 0.244 0.000
N00-N08 Glomerular diseases
0.756 0.244 0.000
I49.8 Other specified cardiac arrhythmias
0.755 0.245 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.754 0.245 0.000
I30 Acute pericarditis
0.754 0.246 0.000
K86.9 Disease of pancreas, unspecified
0.753 0.247 0.000
V10-V19 Pedal cyclist injured in transport accident
0.752 0.248 0.000
K59 Other functional intestinal disorders
0.751 0.248 0.000
K63.2 Fistula of intestine
0.750 0.250 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.750 0.250 0.000
H53-H54 Visual disturbances and blindness
0.749 0.251 0.000
K63.3 Ulcer of intestine
0.749 0.251 0.000
N25-N29 Other disorders of kidney and ureter
0.748 0.252 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.747 0.253 0.000
R12 Heartburn
0.747 0.253 0.000
K35 Acute appendicitis
0.746 0.254 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.745 0.255 0.000
H10-H13 Disorders of conjunctiva
0.744 0.256 0.000
I10-I15 Hypertensive diseases
0.744 0.256 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.743 0.257 0.000
E78.2 Mixed hyperlipidaemia
0.743 0.257 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.741 0.259 0.000
S10-S19 Injuries to the neck
0.741 0.259 0.000
I45.1 Other and unspecified right bundle-branch block
0.739 0.261 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.739 0.261 0.000
M65-M68 Disorders of synovium and tendon
0.738 0.262 0.000
M46 Other inflammatory spondylopathies
0.738 0.262 0.000
I33 Acute and subacute endocarditis
0.737 0.263 0.000
R50 Fever of unknown origin
0.737 0.263 0.000
M40-M43 Deforming dorsopathies
0.736 0.264 0.000
R14 Flatulence and related conditions
0.736 0.264 0.000
S01.5 Open wound of lip and oral cavity
0.736 0.264 0.000
K56.1 Intussusception
0.736 0.264 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.735 0.265 0.000
S20-S29 Injuries to the thorax
0.735 0.265 0.000
S01.3 Open wound of ear
0.735 0.265 0.000
K82 Other diseases of gallbladder
0.733 0.267 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.733 0.267 0.000
K92.0 Haematemesis
0.732 0.268 0.000
K56.4 Other impaction of intestine
0.731 0.269 0.000
T79-T79 Certain early complications of trauma
0.727 0.273 0.000
E14.9 Without complications
0.727 0.273 0.000
K83.8 Other specified diseases of biliary tract
0.726 0.274 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.726 0.274 0.000
E03 Other hypothyroidism
0.726 0.274 0.000
E87.6 Hypokalaemia
0.725 0.275 0.000
M25.7 Osteophyte
0.725 0.275 0.000
S00.8 Superficial injury of other parts of head
0.724 0.276 0.000
S50-S59 Injuries to the elbow and forearm
0.724 0.276 0.000
W20-W49 Exposure to inanimate mechanical forces
0.723 0.277 0.000
H65-H75 Diseases of middle ear and mastoid
0.721 0.279 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.721 0.279 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.721 0.279 0.000
I87 Other disorders of veins
0.721 0.279 0.000
I49.3 Ventricular premature depolarisation
0.720 0.280 0.000
S42 Fracture of shoulder and upper arm
0.720 0.280 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.719 0.281 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.719 0.281 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.719 0.281 0.000
T40.2 Other opioids
0.719 0.281 0.000
T43.2 Other and unspecified antidepressants
0.718 0.282 0.000
I22.8 Subsequent myocardial infarction of other sites
0.718 0.282 0.000
R00.1 Bradycardia, unspecified
0.718 0.282 0.000
K63.1 Perforation of intestine (nontraumatic)
0.718 0.282 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
E40-E46 Malnutrition
0.717 0.283 0.000
H25.1 Senile nuclear cataract
0.717 0.283 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.716 0.284 0.000
G62 Other polyneuropathies
0.716 0.284 0.000
S08 Traumatic amputation of part of head
0.714 0.286 0.000
S07 Crushing injury of head
0.714 0.286 0.000
S05 Injury of eye and orbit
0.714 0.286 0.000
S04 Injury of cranial nerves
0.714 0.286 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.714 0.286 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.714 0.286 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.714 0.286 0.000
K09 Cysts of oral region, not elsewhere classified
0.713 0.286 0.000
K03 Other diseases of hard tissues of teeth
0.713 0.286 0.000
K00 Disorders of tooth development and eruption
0.713 0.286 0.000
K50.1 Crohn's disease of large intestine
0.713 0.287 0.000
E85 Amyloidosis
0.713 0.287 0.000
E84 Cystic fibrosis
0.713 0.287 0.000
E79 Disorders of purine and pyrimidine metabolism
0.713 0.287 0.000
E77 Disorders of glycoprotein metabolism
0.713 0.287 0.000
E76 Disorders of glycosaminoglycan metabolism
0.713 0.287 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.713 0.287 0.000
E74 Other disorders of carbohydrate metabolism
0.713 0.287 0.000
E73 Lactose intolerance
0.713 0.287 0.000
E72 Other disorders of amino-acid metabolism
0.713 0.287 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.713 0.287 0.000
E70 Disorders of aromatic amino-acid metabolism
0.713 0.287 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.713 0.287 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.712 0.288 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.712 0.288 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.712 0.288 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.712 0.288 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.712 0.288 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.712 0.288 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.712 0.288 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.712 0.288 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.712 0.288 0.000
T36 Poisoning by systemic antibiotics
0.712 0.288 0.000
R54 Senility
0.712 0.288 0.000
F99-F99 Unspecified mental disorder
0.712 0.288 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.712 0.288 0.000
F80-F89 Disorders of psychological development
0.712 0.288 0.000
F70-F79 Mental retardation
0.712 0.288 0.000
I08 Multiple valve diseases
0.712 0.288 0.000
K02.8 Other dental caries
0.711 0.289 0.000
K02.5 Caries with pulp exposure
0.711 0.289 0.000
K02.4 Odontoclasia
0.711 0.289 0.000
K02.3 Arrested dental caries
0.711 0.289 0.000
K02.2 Caries of cementum
0.711 0.289 0.000
K02.1 Caries of dentin
0.711 0.289 0.000
K02.0 Caries limited to enamel
0.711 0.289 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.711 0.289 0.000
M91-M94 Chondropathies
0.711 0.289 0.000
M00-M03 Infectious arthropathies
0.711 0.289 0.000
H43-H45 Disorders of vitreous body and globe
0.710 0.290 0.000
I45.9 Conduction disorder, unspecified
0.710 0.290 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.709 0.290 0.000
R56 Convulsions, not elsewhere classified
0.709 0.291 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.709 0.291 0.000
M21 Other acquired deformities of limbs
0.708 0.292 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.708 0.292 0.000
K83.1 Obstruction of bile duct
0.707 0.293 0.000
F30 Manic episode
0.706 0.294 0.000
S02 Fracture of skull and facial bones
0.706 0.294 0.000
K10 Other diseases of jaws
0.706 0.294 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.705 0.295 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.705 0.295 0.000
N18.3 Chronic kidney disease, stage 3
0.705 0.295 0.000
M47.9 Spondylosis, unspecified
0.704 0.296 0.000
K85.9 Acute pancreatitis, unspecified
0.704 0.296 0.000
S01.0 Open wound of scalp
0.704 0.296 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.703 0.297 0.000
I27 Other pulmonary heart diseases
0.703 0.297 0.000
I70 Atherosclerosis
0.702 0.298 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.701 0.298 0.000
E78.8 Other disorders of lipoprotein metabolism
0.701 0.299 0.000
E78.6 Lipoprotein deficiency
0.701 0.299 0.000
E78.4 Other hyperlipidaemia
0.701 0.299 0.000
E78.3 Hyperchylomicronaemia
0.701 0.299 0.000
E78.1 Pure hyperglyceridaemia
0.701 0.299 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.700 0.300 0.000
K52 Other non-infective gastro-enteritis and colitis
0.700 0.300 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.700 0.300 0.000
I63.9 Cerebral infarction, unspecified
0.700 0.300 0.000
K55.2 Angiodysplasia of colon
0.699 0.301 0.000
R07.0 Pain in throat
0.698 0.302 0.000
K63.4 Enteroptosis
0.698 0.302 0.000
K63.0 Abscess of intestine
0.698 0.302 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.698 0.302 0.000
E05.9 Thyrotoxicosis, unspecified
0.697 0.303 0.000
I45.5 Other specified heart block
0.696 0.303 0.000
B15-B19 Viral hepatitis
0.696 0.304 0.000
I82 Other venous embolism and thrombosis
0.696 0.304 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.696 0.304 0.000
E87.4 Mixed disorder of acid-base balance
0.696 0.304 0.000
E87.3 Alkalosis
0.696 0.304 0.000
M31 Other necrotising vasculopathies
0.695 0.305 0.000
R59 Enlarged lymph nodes
0.695 0.305 0.000
I95 Hypotension
0.695 0.305 0.000
N10-N16 Renal tubulo-interstitial diseases
0.695 0.305 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.695 0.305 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.694 0.306 0.000
F31 Bipolar affective disorder
0.694 0.306 0.000
N17.9 Acute renal failure, unspecified
0.694 0.306 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.694 0.306 0.000
E88 Other metabolic disorders
0.694 0.306 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.694 0.306 0.000
E87.0 Hyperosmolality and hypernatraemia
0.694 0.306 0.000
I46.1 Sudden cardiac death, so described
0.693 0.307 0.000
E13 Other specified diabetes mellitus
0.693 0.307 0.000
M35 Other systemic involvement of connective tissue
0.692 0.308 0.000
F10.0 Acute intoxication
0.692 0.308 0.000
K86.2 Cyst of pancreas
0.692 0.308 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.690 0.310 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.690 0.310 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.690 0.310 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.690 0.310 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.690 0.310 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.690 0.310 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.690 0.310 0.000
F11 Mental and behavioural disorders due to use of opioids
0.690 0.310 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.689 0.311 0.000
Q60-Q64 Congenital malformations of the urinary system
0.688 0.312 0.000
I24.1 Dressler's syndrome
0.688 0.312 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.688 0.312 0.000
F40.2 Specific (isolated) phobias
0.688 0.312 0.000
M62 Other disorders of muscle
0.688 0.312 0.000
R58 Haemorrhage, not elsewhere classified
0.688 0.312 0.000
M47.8 Other spondylosis
0.686 0.314 0.000
M79.8 Other specified soft tissue disorders
0.686 0.314 0.000
S01.7 Multiple open wounds of head
0.685 0.315 0.000
S01.4 Open wound of cheek and temporomandibular area
0.685 0.315 0.000
S90-S99 Injuries to the ankle and foot
0.685 0.315 0.000
X60-X84 Intentional self-harm
0.685 0.315 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.684 0.316 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.683 0.317 0.000
S00.5 Superficial injury of lip and oral cavity
0.683 0.317 0.000
S00.4 Superficial injury of ear
0.683 0.317 0.000
S00.3 Superficial injury of nose
0.683 0.317 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.683 0.317 0.000
S00.1 Contusion of eyelid and periocular area
0.683 0.317 0.000
E27 Other disorders of adrenal gland
0.683 0.317 0.000
M79.6 Pain in limb
0.683 0.317 0.000
M47.2 Other spondylosis with radiculopathy
0.682 0.318 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.682 0.318 0.000
K50.9 Crohn's disease, unspecified
0.681 0.319 0.000
N18.0 End-stage renal disease
0.680 0.319 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.679 0.321 0.000
N99-N99 Other disorders of the genitourinary system
0.679 0.321 0.000
M86-M90 Other osteopathies
0.678 0.322 0.000
E11.3 With ophthalmic complications
0.677 0.323 0.000
K92.8 Other specified diseases of digestive system
0.677 0.323 0.000
E16 Other disorders of pancreatic internal secretion
0.677 0.323 0.000
S60 Superficial injury of wrist and hand
0.676 0.324 0.000
N76 Other inflammation of vagina and vulva
0.676 0.324 0.000
K70 Alcoholic liver disease
0.676 0.324 0.000
E12 Malnutrition-related diabetes mellitus
0.676 0.324 0.000
G70-G73 Diseases of myoneural junction and muscle
0.675 0.324 0.000
G54 Nerve root and plexus disorders
0.675 0.325 0.000
K86.3 Pseudocyst of pancreas
0.674 0.325 0.000
G57 Mononeuropathies of lower limb
0.674 0.326 0.000
K91.3 Postoperative intestinal obstruction
0.674 0.326 0.000
K63.9 Disease of intestine, unspecified
0.673 0.327 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.673 0.327 0.000
S01.2 Open wound of nose
0.672 0.327 0.000
R50.9 Fever, unspecified
0.672 0.328 0.000
E21.3 Hyperparathyroidism, unspecified
0.670 0.330 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.669 0.331 0.000
I73 Other peripheral vascular diseases
0.669 0.331 0.000
G60 Hereditary and idiopathic neuropathy
0.669 0.331 0.000
A49 Bacterial infection of unspecified site
0.669 0.331 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.669 0.331 0.000
S67 Crushing injury of wrist and hand
0.668 0.331 0.000
G40-G47 Episodic and paroxysmal disorders
0.668 0.331 0.000
I20.1 Angina pectoris with documented spasm
0.668 0.332 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.668 0.332 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.667 0.332 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.667 0.333 0.000
S42.0 Fracture of clavicle
0.667 0.333 0.000
M23.8 Other internal derangements of knee
0.667 0.333 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.666 0.334 0.000
E14.3 With ophthalmic complications
0.666 0.334 0.000
N75 Diseases of Bartholin's gland
0.666 0.334 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.666 0.334 0.000
M34 Systemic sclerosis
0.666 0.334 0.000
M33 Dermatopolymyositis
0.666 0.334 0.000
M32 Systemic lupus erythematosus
0.666 0.334 0.000
M30 Polyarteritis nodosa and related conditions
0.666 0.334 0.000
A80-A89 Viral infections of the central nervous system
0.666 0.334 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.666 0.334 0.000
Y35-Y36 Legal intervention and operations of war
0.666 0.334 0.000
Y10-Y34 Event of undetermined intent
0.666 0.334 0.000
Y00-Y09 Assault
0.666 0.334 0.000
X85-X99 Assault
0.666 0.334 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.666 0.334 0.000
X50-X57 Overexertion, travel and privation
0.666 0.334 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.666 0.334 0.000
X30-X39 Exposure to forces of nature
0.666 0.334 0.000
X20-X29 Contact with venomous animals and plants
0.666 0.334 0.000
X10-X19 Contact with heat and hot substances
0.666 0.334 0.000
X00-X09 Exposure to smoke, fire and flames
0.666 0.334 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.666 0.334 0.000
W75-W84 Other accidental threats to breathing
0.666 0.334 0.000
W65-W74 Accidental drowning and submersion
0.666 0.334 0.000
W50-W64 Exposure to animate mechanical forces
0.666 0.334 0.000
V98-V99 Other and unspecified transport accidents
0.666 0.334 0.000
V95-V97 Air and space transport accidents
0.666 0.334 0.000
V90-V94 Water transport accidents
0.666 0.334 0.000
V80-V89 Other land transport accidents
0.666 0.334 0.000
V70-V79 Bus occupant injured in transport accident
0.666 0.334 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.666 0.334 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.666 0.334 0.000
V40-V49 Car occupant injured in transport accident
0.666 0.334 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.666 0.334 0.000
V01-V09 Pedestrian injured in transport accident
0.666 0.334 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.665 0.335 0.000
F43 Reaction to severe stress, and adjustment disorders
0.665 0.335 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.665 0.335 0.000
M45 Ankylosing spondylitis
0.664 0.335 0.000
R47 Speech disturbances, not elsewhere classified
0.664 0.335 0.000
K57.1 Diverticular disease of small intestine without perforation or abscess
0.664 0.336 0.000
V20-V29 Motorcycle rider injured in transport accident
0.663 0.336 0.000
M50-M54 Other dorsopathies
0.663 0.337 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.663 0.337 0.000
H55-H59 Other disorders of eye and adnexa
0.662 0.338 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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