TreeWAS – Variant ID: rs7671654

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	1.000	0.000	0.000
Chapter II Neoplasms	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes	1.000	0.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000	0.000
C15-C26 Malignant neoplasms of digestive organs	0.999	0.001	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.999	0.001	0.000
S60-S69 Injuries to the wrist and hand	0.999	0.001	0.000
C77.2 Intra-abdominal lymph nodes	0.998	0.002	0.000
M20-M25 Other joint disorders	0.997	0.003	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.989	0.011	0.000
M45-M49 Spondylopathies	0.984	0.016	0.000
C79 Secondary malignant neoplasm of other sites	0.983	0.017	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.977	0.023	0.000
Chapter XX External causes of morbidity and mortality	0.977	0.023	0.000
C77.0 Lymph nodes of head, face and neck	0.975	0.025	0.000
D00-D09 In situ neoplasms	0.975	0.025	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.969	0.031	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.962	0.038	0.000
C78.0 Secondary malignant neoplasm of lung	0.961	0.039	0.000
M35 Other systemic involvement of connective tissue	0.958	0.042	0.000
C77.1 Intrathoracic lymph nodes	0.953	0.047	0.000
C20 Malignant neoplasm of rectum	0.943	0.057	0.000
C79.8 Secondary malignant neoplasm of other specified sites	0.942	0.058	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.941	0.059	0.000
Chapter X Diseases of the respiratory system	0.933	0.067	0.000
S50-S59 Injuries to the elbow and forearm	0.928	0.072	0.000
J30-J39 Other diseases of upper respiratory tract	0.927	0.073	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.924	0.076	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.923	0.077	0.000
C80 Malignant neoplasm without specification of site	0.922	0.078	0.000
M24 Other specific joint derangements	0.922	0.078	0.000
M48 Other spondylopathies	0.917	0.083	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.915	0.085	0.000
M35.3 Polymyalgia rheumatica	0.913	0.087	0.000
J34 Other disorders of nose and nasal sinuses	0.910	0.090	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.910	0.090	0.000
Y52 Agents primarily affecting the cardiovascular system	0.909	0.091	0.000
S62 Fracture at wrist and hand level	0.908	0.092	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.905	0.095	0.000
M46 Other inflammatory spondylopathies	0.904	0.096	0.000
M22 Disorders of patella	0.899	0.101	0.000
C64-C68 Malignant neoplasms of urinary tract	0.889	0.111	0.000
J60-J70 Lung diseases due to external agents	0.889	0.111	0.000
S61 Open wound of wrist and hand	0.882	0.118	0.000
C77.9 Lymph node, unspecified	0.880	0.120	0.000
J34.3 Hypertrophy of nasal turbinates	0.875	0.125	0.000
M48.0 Spinal stenosis	0.875	0.125	0.000
S52 Fracture of forearm	0.872	0.128	0.000
C25 Malignant neoplasm of pancreas	0.872	0.128	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.870	0.130	0.000
D04 Carcinoma in situ of skin	0.869	0.131	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.862	0.138	0.000
M65-M68 Disorders of synovium and tendon	0.862	0.138	0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.861	0.139	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.860	0.140	0.000
S69 Other and unspecified injuries of wrist and hand	0.860	0.140	0.000
C80.9 Malignant neoplasm, unspecified	0.857	0.143	0.000
C15 Malignant neoplasm of oesophagus	0.856	0.144	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.855	0.145	0.000
M23 Internal derangement of knee	0.851	0.149	0.000
Chapter XXII Codes for special purposes	0.851	0.149	0.000
T90 Sequelae of injuries of head	0.849	0.151	0.000
M47 Spondylosis	0.846	0.154	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.846	0.154	0.000
S60 Superficial injury of wrist and hand	0.845	0.155	0.000
C21 Malignant neoplasm of anus and anal canal	0.844	0.156	0.000
J69 Pneumonitis due to solids and liquids	0.842	0.158	0.000
T79-T79 Certain early complications of trauma	0.832	0.168	0.000
M86-M90 Other osteopathies	0.831	0.169	0.000
J32 Chronic sinusitis	0.826	0.174	0.000
C78.1 Secondary malignant neoplasm of mediastinum	0.825	0.175	0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.822	0.178	0.000
M34 Systemic sclerosis	0.819	0.181	0.000
S62.0 Fracture of navicular [scaphoid] bone of hand	0.819	0.181	0.000
S66.8 Injury of other muscles and tendons at wrist and hand level	0.816	0.184	0.000
C67 Malignant neoplasm of bladder	0.816	0.184	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.815	0.185	0.000
O00-O08 Pregnancy with abortive outcome	0.813	0.186	0.001
M60-M63 Disorders of muscles	0.813	0.187	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.812	0.188	0.000
J69.0 Pneumonitis due to food and vomit	0.809	0.191	0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.807	0.193	0.000
C77.8 Lymph nodes of multiple regions	0.805	0.195	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.805	0.195	0.000
Y40 Systemic antibiotics	0.804	0.196	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.801	0.199	0.000
Y43 Primarily systemic agents	0.799	0.200	0.000
C79.2 Secondary malignant neoplasm of skin	0.797	0.203	0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.794	0.206	0.000
Chapter VIII Diseases of the ear and mastoid process	0.793	0.207	0.000
D05 Carcinoma in situ of breast	0.793	0.207	0.000
S65 Injury of blood vessels at wrist and hand level	0.792	0.207	0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.791	0.209	0.000
O04 Medical abortion	0.791	0.209	0.000
Chapter I Certain infectious and parasitic diseases	0.790	0.210	0.000
M91-M94 Chondropathies	0.790	0.210	0.000
S61.8 Open wound of other parts of wrist and hand	0.788	0.212	0.000
J34.0 Abscess, furuncle and carbuncle of nose	0.786	0.213	0.000
D03 Melanoma in situ	0.785	0.215	0.000
M35.7 Hypermobility syndrome	0.784	0.216	0.000
D07.5 Prostate	0.782	0.218	0.000
M24.2 Disorder of ligament	0.780	0.219	0.000
Q80-Q89 Other congenital malformations	0.780	0.220	0.000
O48 Prolonged pregnancy	0.779	0.221	0.000
M22.2 Patellofemoral disorders	0.779	0.221	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.777	0.223	0.000
S62.8 Fracture of other and unspecified parts of wrist and hand	0.776	0.224	0.000
J32.9 Chronic sinusitis, unspecified	0.776	0.224	0.000
S64 Injury of nerves at wrist and hand level	0.774	0.226	0.000
O04.9 Complete or unspecified, without complication	0.772	0.228	0.000
S10-S19 Injuries to the neck	0.772	0.228	0.000
S67 Crushing injury of wrist and hand	0.771	0.229	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.770	0.230	0.000
C25.0 Head of pancreas	0.768	0.232	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.768	0.232	0.000
S52.6 Fracture of lower end of both ulna and radius	0.767	0.232	0.000
O85-O92 Complications predominantly related to the puerperium	0.767	0.233	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.766	0.234	0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.765	0.235	0.000
S62.2 Fracture of first metacarpal bone	0.763	0.237	0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.762	0.238	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.761	0.239	0.000
D04.7 Skin of lower limb, including hip	0.761	0.239	0.000
S69.9 Unspecified injury of wrist and hand	0.760	0.240	0.000
C78.2 Secondary malignant neoplasm of pleura	0.759	0.241	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.758	0.241	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.757	0.243	0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.756	0.243	0.000
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.756	0.244	0.000
M48.06 Spinal stenosis (Lumbar region)	0.756	0.244	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.755	0.245	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.755	0.245	0.000
C23 Malignant neoplasm of gallbladder	0.753	0.246	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.753	0.247	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.753	0.247	0.000
M24.1 Other articular cartilage disorders	0.751	0.249	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.750	0.249	0.000
X20-X29 Contact with venomous animals and plants	0.750	0.250	0.000
M22.3 Other derangements of patella	0.750	0.250	0.000
S61.0 Open wound of finger(s) without damage to nail	0.750	0.250	0.000
C17 Malignant neoplasm of small intestine	0.749	0.251	0.000
Y00-Y09 Assault	0.748	0.252	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.746	0.254	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.746	0.254	0.000
M25 Other joint disorders, not elsewhere classified	0.745	0.255	0.000
X50-X57 Overexertion, travel and privation	0.745	0.255	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.744	0.256	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.744	0.256	0.000
D05.9 Carcinoma in situ of breast, unspecified	0.743	0.257	0.000
S40-S49 Injuries to the shoulder and upper arm	0.743	0.257	0.000
S52.1 Fracture of upper end of radius	0.742	0.258	0.000
C77.3 Axillary and upper limb lymph nodes	0.742	0.258	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.742	0.258	0.000
M47.8 Other spondylosis	0.741	0.258	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.741	0.259	0.000
D06 Carcinoma in situ of cervix uteri	0.741	0.259	0.000
M65 Synovitis and tenosynovitis	0.740	0.260	0.000
T90.4 Sequelae of injury of eye and orbit	0.739	0.261	0.000
T91 Sequelae of injuries of neck and trunk	0.737	0.263	0.000
D41.4 Bladder	0.737	0.263	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.736	0.264	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.734	0.266	0.000
M47.86 Other spondylosis (Lumbar region)	0.733	0.267	0.000
C77.4 Inguinal and lower limb lymph nodes	0.733	0.267	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.732	0.267	0.000
J09-J18 Influenza and pneumonia	0.732	0.268	0.000
M21 Other acquired deformities of limbs	0.731	0.268	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.728	0.272	0.000
Q60-Q64 Congenital malformations of the urinary system	0.728	0.272	0.000
W50-W64 Exposure to animate mechanical forces	0.726	0.274	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.726	0.274	0.000
V10-V19 Pedal cyclist injured in transport accident	0.726	0.274	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.725	0.275	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.723	0.277	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.722	0.278	0.000
C21.0 Anus, unspecified	0.721	0.279	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.721	0.279	0.000
M89 Other disorders of bone	0.721	0.279	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.719	0.281	0.000
M24.0 Loose body in joint	0.718	0.282	0.000
M48.09 Spinal stenosis (Site unspecified)	0.717	0.283	0.000
C76 Malignant neoplasm of other and ill-defined sites	0.717	0.283	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.717	0.283	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
T33-T35 Frostbite	0.717	0.283	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283	0.000
T00-T07 Injuries involving multiple body regions	0.717	0.283	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.716	0.284	0.000
D04.2 Skin of ear and external auricular canal	0.716	0.284	0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.716	0.284	0.000
J35 Chronic diseases of tonsils and adenoids	0.715	0.285	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.715	0.285	0.000
M33 Dermatopolymyositis	0.715	0.285	0.000
M32 Systemic lupus erythematosus	0.715	0.285	0.000
M30 Polyarteritis nodosa and related conditions	0.715	0.285	0.000
C07 Malignant neoplasm of parotid gland	0.713	0.287	0.000
O30 Multiple gestation	0.712	0.288	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.712	0.288	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.711	0.289	0.000
Q00-Q07 Congenital malformations of the nervous system	0.710	0.290	0.000
S52.7 Multiple fractures of forearm	0.710	0.290	0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.709	0.291	0.000
C65 Malignant neoplasm of renal pelvis	0.709	0.291	0.000
C78.4 Secondary malignant neoplasm of small intestine	0.709	0.291	0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.709	0.291	0.000
J67 Hypersensitivity pneumonitis due to organic dust	0.709	0.291	0.000
M22.8 Other disorders of patella	0.709	0.291	0.000
C79.6 Secondary malignant neoplasm of ovary	0.708	0.292	0.000
J34.1 Cyst and mucocele of nose and nasal sinus	0.707	0.293	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.706	0.294	0.000
M49 Spondylopathies in diseases classified elsewhere	0.706	0.294	0.000
O44 Placenta praevia	0.705	0.294	0.000
C15.9 Oesophagus, unspecified	0.703	0.296	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.703	0.297	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.702	0.298	0.000
S50 Superficial injury of forearm	0.702	0.298	0.000
T98 Sequelae of other and unspecified effects of external causes	0.701	0.299	0.000
M47.1 Other spondylosis with myelopathy	0.701	0.299	0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.700	0.300	0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.700	0.300	0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.700	0.300	0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.700	0.300	0.000
Y35-Y36 Legal intervention and operations of war	0.700	0.300	0.000
Y10-Y34 Event of undetermined intent	0.700	0.300	0.000
X85-X99 Assault	0.700	0.300	0.000
X30-X39 Exposure to forces of nature	0.700	0.300	0.000
X10-X19 Contact with heat and hot substances	0.700	0.300	0.000
X00-X09 Exposure to smoke, fire and flames	0.700	0.300	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.700	0.300	0.000
W75-W84 Other accidental threats to breathing	0.700	0.300	0.000
W65-W74 Accidental drowning and submersion	0.700	0.300	0.000
V98-V99 Other and unspecified transport accidents	0.700	0.300	0.000
V95-V97 Air and space transport accidents	0.700	0.300	0.000
V90-V94 Water transport accidents	0.700	0.300	0.000
V70-V79 Bus occupant injured in transport accident	0.700	0.300	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.700	0.300	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.700	0.300	0.000
V40-V49 Car occupant injured in transport accident	0.700	0.300	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.700	0.300	0.000
V01-V09 Pedestrian injured in transport accident	0.700	0.300	0.000
S70-S79 Injuries to the hip and thigh	0.700	0.300	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.700	0.300	0.000
D02 Carcinoma in situ of middle ear and respiratory system	0.699	0.301	0.000
D01 Carcinoma in situ of other and unspecified digestive organs	0.699	0.301	0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.699	0.301	0.000
S60.9 Superficial injury of wrist and hand, unspecified	0.699	0.301	0.000
M00-M03 Infectious arthropathies	0.698	0.301	0.000
C51-C58 Malignant neoplasms of female genital organs	0.698	0.302	0.000
C04 Malignant neoplasm of floor of mouth	0.698	0.302	0.000
C10 Malignant neoplasm of oropharynx	0.698	0.302	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.698	0.302	0.000
Q76 Congenital malformations of spine and bony thorax	0.698	0.302	0.000
C80.0 Malignant neoplasm, primary site unknown, so stated	0.697	0.303	0.000
J32.8 Other chronic sinusitis	0.697	0.303	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.696	0.304	0.000
S68 Traumatic amputation of wrist and hand	0.696	0.304	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.695	0.305	0.000
H65-H75 Diseases of middle ear and mastoid	0.694	0.306	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.693	0.307	0.000
O43 Placental disorders	0.693	0.307	0.000
S52.60 Fracture of lower end of both ulna and radius (closed)	0.692	0.308	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.692	0.308	0.000
M35.0 Sicca syndrome [Sjogren]	0.692	0.308	0.000
C15.5 Lower third of oesophagus	0.692	0.308	0.000
M34.9 Systemic sclerosis, unspecified	0.692	0.308	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.692	0.308	0.000
V80-V89 Other land transport accidents	0.691	0.309	0.000
C79.9 Secondary malignant neoplasm, unspecified site	0.690	0.310	0.000
Y59 Other and unspecified vaccines and biological substances	0.690	0.310	0.000
Y58 Bacterial vaccines	0.690	0.310	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.690	0.310	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.690	0.310	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.690	0.310	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.690	0.310	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.690	0.310	0.000
Y48 Anaesthetics and therapeutic gases	0.690	0.310	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.690	0.310	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.690	0.310	0.000
C67.4 Posterior wall of bladder	0.690	0.310	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.689	0.311	0.000
C67.2 Lateral wall of bladder	0.689	0.311	0.000
W00-W19 Falls	0.687	0.313	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.687	0.313	0.000
M35.8 Other specified systemic involvement of connective tissue	0.687	0.313	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.687	0.313	0.000
M35.5 Multifocal fibrosclerosis	0.687	0.313	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.687	0.313	0.000
M35.2 Behcet's disease	0.687	0.313	0.000
M35.1 Other overlap syndromes	0.687	0.313	0.000
J37 Chronic laryngitis and laryngotracheitis	0.686	0.314	0.000
J38.1 Polyp of vocal cord and larynx	0.686	0.314	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.686	0.314	0.000
D45 Polycythaemia vera	0.685	0.315	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.685	0.315	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.684	0.316	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.683	0.317	0.000
C09 Malignant neoplasm of tonsil	0.682	0.318	0.000
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.682	0.318	0.000
Y40.9 Systemic antibiotic, unspecified	0.681	0.319	0.000
Y52.1 Calcium-channel blockers	0.681	0.319	0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.679	0.321	0.000
M62 Other disorders of muscle	0.679	0.321	0.000
J34.8 Other specified disorders of nose and nasal sinuses	0.678	0.322	0.000
M31 Other necrotising vasculopathies	0.677	0.323	0.000
C01 Malignant neoplasm of base of tongue	0.676	0.324	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.675	0.325	0.000
Q35-Q37 Cleft lip and cleft palate	0.675	0.325	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.675	0.325	0.000
J38.4 Oedema of larynx	0.675	0.325	0.000
O36 Maternal care for other known or suspected foetal problems	0.674	0.326	0.000
J30 Vasomotor and allergic rhinitis	0.674	0.326	0.000
D09 Carcinoma in situ of other and unspecified sites	0.673	0.327	0.000
M23.3 Other meniscus derangements	0.672	0.328	0.000
Y54.3 Benzothiadiazine derivatives	0.671	0.328	0.000
M45 Ankylosing spondylitis	0.670	0.329	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.669	0.330	0.000
M23.8 Other internal derangements of knee	0.669	0.331	0.000
C16 Malignant neoplasm of stomach	0.668	0.332	0.000
C50-C50 Malignant neoplasm of breast	0.668	0.332	0.000
M67 Other disorders of synovium and tendon	0.666	0.334	0.000
S59 Other and unspecified injuries of forearm	0.666	0.334	0.000
S58 Traumatic amputation of forearm	0.666	0.334	0.000
S57 Crushing injury of forearm	0.666	0.334	0.000
S56 Injury of muscle and tendon at forearm level	0.666	0.334	0.000
S55 Injury of blood vessels at forearm level	0.666	0.334	0.000
S54 Injury of nerves at forearm level	0.666	0.334	0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.666	0.334	0.000
D46 Myelodysplastic syndromes	0.666	0.334	0.000
H65 Nonsuppurative otitis media	0.666	0.334	0.000
X60-X84 Intentional self-harm	0.664	0.335	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.664	0.336	0.000
M70-M79 Other soft tissue disorders	0.664	0.336	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.664	0.336	0.000
D38.1 Trachea, bronchus and lung	0.663	0.337	0.000
S60.8 Other superficial injuries of wrist and hand	0.663	0.337	0.000
T95 Sequelae of burns, corrosions and frostbite	0.662	0.338	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.662	0.338	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.662	0.338	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.662	0.338	0.000
Q50-Q56 Congenital malformations of genital organs	0.661	0.339	0.000
M24.9 Joint derangement, unspecified	0.661	0.339	0.000
M24.7 Protrusio acetabuli	0.661	0.339	0.000
M24.6 Ankylosis of joint	0.661	0.339	0.000
M24.5 Contracture of joint	0.661	0.339	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.661	0.339	0.000
Y86 Sequelae of other accidents	0.659	0.341	0.000
S62.20 Fracture of first metacarpal bone (closed)	0.658	0.342	0.000
M48.9 Spondylopathy, unspecified	0.658	0.342	0.000
M48.8 Other specified spondylopathies	0.658	0.342	0.000
M48.4 Fatigue fracture of vertebra	0.658	0.342	0.000
M48.3 Traumatic spondylopathy	0.658	0.342	0.000
M48.2 Kissing spine	0.658	0.342	0.000
M48.1 Ankylosing hyperostosis [Forestier]	0.658	0.342	0.000
J36 Peritonsillar abscess	0.657	0.343	0.000
M23.2 Derangement of meniscus due to old tear or injury	0.657	0.343	0.000
Chapter IX Diseases of the circulatory system	0.657	0.343	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.656	0.344	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.656	0.344	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.656	0.344	0.000
S36 Injury of intra-abdominal organs	0.655	0.345	0.000
O90 Complications of the puerperium, not elsewhere classified	0.654	0.346	0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.653	0.347	0.000
C25.9 Pancreas, unspecified	0.653	0.347	0.000
D04.3 Skin of other and unspecified parts of face	0.653	0.347	0.000
S51 Open wound of forearm	0.652	0.348	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.652	0.348	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.652	0.348	0.000
Y52.7 Peripheral vasodilators	0.652	0.348	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.652	0.348	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.652	0.348	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.652	0.348	0.000
S62.7 Multiple fractures of fingers	0.651	0.349	0.000
S62.4 Multiple fractures of metacarpal bones	0.651	0.349	0.000
S62.1 Fracture of other carpal bone(s)	0.651	0.349	0.000
J34.2 Deviated nasal septum	0.651	0.349	0.000
Q82 Other congenital malformations of skin	0.651	0.349	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.650	0.349	0.000
S52.10 Fracture of upper end of radius (closed)	0.649	0.351	0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.649	0.351	0.000
C13 Malignant neoplasm of hypopharynx	0.649	0.351	0.000
C11 Malignant neoplasm of nasopharynx	0.649	0.351	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.649	0.351	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.649	0.351	0.000
C05 Malignant neoplasm of palate	0.649	0.351	0.000
C03 Malignant neoplasm of gum	0.649	0.351	0.000
C00 Malignant neoplasm of lip	0.649	0.351	0.000
C12 Malignant neoplasm of pyriform sinus	0.649	0.351	0.000
M46.8 Other specified inflammatory spondylopathies	0.648	0.352	0.000
M46.5 Other infective spondylopathies	0.648	0.352	0.000
M46.4 Discitis, unspecified	0.648	0.352	0.000
M46.3 Infection of intervertebral disk (pyogenic)	0.648	0.352	0.000
M46.2 Osteomyelitis of vertebra	0.648	0.352	0.000
M46.1 Sacro-iliitis, not elsewhere classified	0.648	0.352	0.000
M46.0 Spinal enthesopathy	0.648	0.352	0.000
Y85 Sequelae of transport accidents	0.648	0.352	0.000
Y57 Other and unspecified drugs and medicaments	0.647	0.352	0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.646	0.354	0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.646	0.354	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.646	0.354	0.000
V20-V29 Motorcycle rider injured in transport accident	0.646	0.354	0.000
M48.02 Spinal stenosis (Cervical region)	0.645	0.355	0.000
Y43.4 Immunosuppressive agents	0.645	0.355	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.645	0.355	0.000
S61.7 Multiple open wounds of wrist and hand	0.645	0.355	0.000
M20 Acquired deformities of fingers and toes	0.645	0.355	0.000
S65.0 Injury of ulnar artery at wrist and hand level	0.644	0.356	0.000
M22.1 Recurrent subluxation of patella	0.644	0.356	0.000
M22.9 Disorder of patella, unspecified	0.644	0.356	0.000
M22.0 Recurrent dislocation of patella	0.644	0.356	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.644	0.356	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.643	0.356	0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.643	0.357	0.000
H60-H62 Diseases of external ear	0.642	0.358	0.000
T92 Sequelae of injuries of upper limb	0.642	0.358	0.000
M48.00 Spinal stenosis (Multiple sites in spine)	0.640	0.360	0.000
O41 Other disorders of amniotic fluid and membranes	0.640	0.360	0.000
C78.7 Secondary malignant neoplasm of liver	0.639	0.361	0.000
M23.4 Loose body in knee	0.638	0.362	0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.638	0.362	0.000
C68 Malignant neoplasm of other and unspecified urinary organs	0.637	0.362	0.000
C66 Malignant neoplasm of ureter	0.637	0.362	0.000
J70 Respiratory conditions due to other external agents	0.637	0.363	0.000
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours	0.637	0.363	0.000
J66 Airway disease due to specific organic dust	0.637	0.363	0.000
J63 Pneumoconiosis due to other inorganic dusts	0.637	0.363	0.000
J62 Pneumoconiosis due to dust containing silica	0.637	0.363	0.000
J65 Pneumoconiosis associated with tuberculosis	0.637	0.363	0.000
J64 Unspecified pneumoconiosis	0.637	0.363	0.000
J60 Coalworker's pneumoconiosis	0.637	0.363	0.000
T66-T78 Other and unspecified effects of external causes	0.636	0.364	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.635	0.365	0.000
S52.5 Fracture of lower end of radius	0.635	0.365	0.000
M24.23 Disorder of ligament (Forearm)	0.633	0.367	0.000
S90-S99 Injuries to the ankle and foot	0.633	0.367	0.000
Y42.5 Other oestrogens and progestogens	0.632	0.368	0.000
M94 Other disorders of cartilage	0.631	0.368	0.000
M47.2 Other spondylosis with radiculopathy	0.631	0.369	0.000
C43 Malignant melanoma of skin	0.631	0.369	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.630	0.370	0.000
C21.1 Anal canal	0.629	0.370	0.000
M40-M43 Deforming dorsopathies	0.629	0.371	0.000
Y43.3 Other antineoplastic drugs	0.628	0.372	0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.627	0.373	0.000
M48.05 Spinal stenosis (Thoracolumbar region)	0.627	0.373	0.000
M48.04 Spinal stenosis (Thoracic region)	0.627	0.373	0.000
M48.03 Spinal stenosis (Cervicothoracic region)	0.627	0.373	0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.627	0.373	0.000
M48.5 Collapsed vertebra, not elsewhere classified	0.627	0.373	0.000
T93 Sequelae of injuries of lower limb	0.627	0.373	0.000
B07 Viral warts	0.627	0.373	0.000
S62.3 Fracture of other metacarpal bone	0.626	0.374	0.000
S52.0 Fracture of upper end of ulna	0.626	0.374	0.000
S52.9 Fracture of forearm, part unspecified	0.625	0.374	0.000
S52.4 Fracture of shafts of both ulna and radius	0.625	0.374	0.000
S52.3 Fracture of shaft of radius	0.625	0.374	0.000
S52.2 Fracture of shaft of ulna	0.625	0.374	0.000
C25.8 Overlapping lesion of pancreas	0.625	0.375	0.000
C25.7 Other parts of pancreas	0.625	0.375	0.000
C25.4 Endocrine pancreas	0.625	0.375	0.000
C25.3 Pancreatic duct	0.625	0.375	0.000
C25.2 Tail of pancreas	0.625	0.375	0.000
C25.1 Body of pancreas	0.625	0.375	0.000
O45 Premature separation of placenta [abruptio placentae]	0.623	0.376	0.000
O33 Maternal care for known or suspected disproportion	0.623	0.376	0.000
O31 Complications specific to multiple gestation	0.623	0.376	0.000
O40 Polyhydramnios	0.623	0.376	0.000
D04.9 Skin, unspecified	0.623	0.377	0.000
D04.8 Skin of other sites	0.623	0.377	0.000
D04.5 Skin of trunk	0.623	0.377	0.000
D04.4 Skin of scalp and neck	0.623	0.377	0.000
D04.1 Skin of eyelid, including canthus	0.623	0.377	0.000
D04.0 Skin of lip	0.623	0.377	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.622	0.378	0.000
W20-W49 Exposure to inanimate mechanical forces	0.620	0.380	0.000
C67.6 Ureteric orifice	0.620	0.380	0.000
D07.6 Other and unspecified male genital organs	0.618	0.382	0.000
D07.4 Penis	0.618	0.382	0.000
D07.3 Other and unspecified female genital organs	0.618	0.382	0.000
D07.2 Vagina	0.618	0.382	0.000
D07.1 Vulva	0.618	0.382	0.000
D07.0 Endometrium	0.618	0.382	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.618	0.382	0.000
M66 Spontaneous rupture of synovium and tendon	0.618	0.382	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.617	0.383	0.000
S37 Injury of urinary and pelvic organs	0.617	0.383	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.617	0.383	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.617	0.383	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.617	0.383	0.000
S31 Open wound of abdomen, lower back and pelvis	0.617	0.383	0.000
S69.8 Other specified injuries of wrist and hand	0.616	0.383	0.000
S69.7 Multiple injuries of wrist and hand	0.616	0.383	0.000
S62.5 Fracture of thumb	0.616	0.383	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.616	0.384	0.000
S64.0 Injury of ulnar nerve at wrist and hand level	0.616	0.384	0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.615	0.385	0.000
J10 Influenza due to identified influenza virus	0.615	0.385	0.000
C15.8 Overlapping lesion of oesophagus	0.613	0.386	0.000
C15.4 Middle third of oesophagus	0.613	0.386	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations