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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs76718115
log Bayes Factor = 14.4603
Chromosome 9   position 112,413,997  (GRCh37) Explore rs76718115 on Ensembl!
Variant rs76718115 is part of Cluster X0148

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
M20-M25 Other joint disorders
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
J40-J47 Chronic lower respiratory diseases
0.998 0.002 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.998 0.002 0.000
Chapter VI Diseases of the nervous system
0.997 0.003 0.000
M25 Other joint disorders, not elsewhere classified
0.997 0.003 0.000
J44 Other chronic obstructive pulmonary disease
0.993 0.007 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.991 0.009 0.000
Chapter XIV Diseases of the genitourinary system
0.990 0.010 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.983 0.017 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.977 0.023 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.975 0.025 0.000
Chapter XI Diseases of the digestive system
0.975 0.025 0.000
K70-K77 Diseases of liver
0.971 0.029 0.000
N40-N51 Diseases of male genital organs
0.968 0.032 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.964 0.036 0.000
M25.5 Pain in joint
0.963 0.037 0.000
K76 Other diseases of liver
0.959 0.041 0.000
J47 Bronchiectasis
0.959 0.041 0.000
S60-S69 Injuries to the wrist and hand
0.951 0.049 0.000
N40 Hyperplasia of prostate
0.950 0.050 0.000
M25.7 Osteophyte
0.947 0.053 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.944 0.056 0.000
N10-N16 Renal tubulo-interstitial diseases
0.942 0.058 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.939 0.061 0.000
M70-M79 Other soft tissue disorders
0.935 0.065 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.931 0.069 0.000
Chapter XXI Factors influencing health status and contact with health services
0.931 0.069 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.927 0.073 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.926 0.074 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.923 0.077 0.000
J20-J22 Other acute lower respiratory infections
0.919 0.081 0.000
S00-S09 Injuries to the head
0.919 0.081 0.000
N48 Other disorders of penis
0.917 0.083 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.914 0.086 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.914 0.086 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.914 0.086 0.000
Z92 Personal history of medical treatment
0.913 0.087 0.000
O36 Maternal care for other known or suspected foetal problems
0.906 0.094 0.000
K76.9 Liver disease, unspecified
0.906 0.094 0.000
S70-S79 Injuries to the hip and thigh
0.905 0.095 0.000
N13 Obstructive and reflux uropathy
0.904 0.096 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.901 0.099 0.000
Z92.3 Personal history of irradiation
0.900 0.100 0.000
N60-N64 Disorders of breast
0.896 0.104 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.894 0.106 0.000
O26.8 Other specified pregnancy-related conditions
0.894 0.106 0.000
D75 Other diseases of blood and blood-forming organs
0.889 0.111 0.000
D60-D64 Aplastic and other anaemias
0.888 0.112 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.883 0.117 0.000
N13.3 Other and unspecified hydronephrosis
0.880 0.120 0.000
M24 Other specific joint derangements
0.873 0.127 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.872 0.128 0.000
Chapter VII Diseases of the eye and adnexa
0.867 0.133 0.000
M25.77 Osteophyte (Ankle and foot)
0.864 0.136 0.000
J95-J99 Other diseases of the respiratory system
0.862 0.138 0.000
O47 False labour
0.859 0.141 0.000
S01 Open wound of head
0.859 0.141 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.859 0.141 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.858 0.142 0.000
G81 Hemiplegia
0.855 0.145 0.000
J43 Emphysema
0.854 0.146 0.000
M25.4 Effusion of joint
0.851 0.149 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.851 0.149 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.849 0.151 0.000
D75.1 Secondary polycythaemia
0.847 0.153 0.000
S72 Fracture of femur
0.846 0.154 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.846 0.154 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.845 0.155 0.000
M21 Other acquired deformities of limbs
0.841 0.159 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.840 0.160 0.000
J22 Unspecified acute lower respiratory infection
0.838 0.162 0.000
H53-H54 Visual disturbances and blindness
0.837 0.163 0.000
G20-G26 Extrapyramidal and movement disorders
0.835 0.165 0.000
N48.8 Other specified disorders of penis
0.835 0.165 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.829 0.171 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.829 0.171 0.000
O26.9 Pregnancy-related condition, unspecified
0.828 0.172 0.000
M72 Fibroblastic disorders
0.827 0.173 0.000
T81 Complications of procedures, not elsewhere classified
0.827 0.173 0.000
M22 Disorders of patella
0.827 0.173 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.826 0.174 0.000
N62 Hypertrophy of breast
0.826 0.174 0.000
D64 Other anaemias
0.825 0.175 0.000
Z93 Artificial opening status
0.825 0.175 0.000
O20 Haemorrhage in early pregnancy
0.825 0.175 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.824 0.176 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.816 0.184 0.000
K75 Other inflammatory liver diseases
0.814 0.186 0.000
S64 Injury of nerves at wrist and hand level
0.813 0.187 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.812 0.188 0.000
M80-M85 Disorders of bone density and structure
0.811 0.189 0.000
N30-N39 Other diseases of urinary system
0.809 0.191 0.000
O36.9 Maternal care for foetal problem, unspecified
0.808 0.192 0.000
M25.8 Other specified joint disorders
0.808 0.192 0.000
H53 Visual disturbances
0.808 0.192 0.000
O80-O84 Delivery
0.807 0.193 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.806 0.194 0.000
S90-S99 Injuries to the ankle and foot
0.806 0.194 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.805 0.195 0.000
M40-M43 Deforming dorsopathies
0.805 0.195 0.000
K65-K67 Diseases of peritoneum
0.805 0.195 0.000
G81.9 Hemiplegia, unspecified
0.804 0.196 0.000
S60 Superficial injury of wrist and hand
0.804 0.196 0.000
G35 Multiple sclerosis
0.800 0.200 0.000
S50-S59 Injuries to the elbow and forearm
0.799 0.201 0.000
M25.50 Pain in joint (Multiple sites)
0.798 0.202 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.796 0.204 0.000
Chapter I Certain infectious and parasitic diseases
0.796 0.204 0.000
N48.4 Impotence of organic origin
0.795 0.205 0.000
D50-D53 Nutritional anaemias
0.791 0.209 0.000
G90-G99 Other disorders of the nervous system
0.791 0.209 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.787 0.213 0.000
K02 Dental caries
0.786 0.214 0.000
M25.52 Pain in joint (Upper arm)
0.786 0.214 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.785 0.215 0.000
S67 Crushing injury of wrist and hand
0.785 0.215 0.000
G61 Inflammatory polyneuropathy
0.784 0.216 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.783 0.217 0.000
T87 Complications peculiar to reattachment and amputation
0.782 0.217 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.782 0.218 0.000
H53.8 Other visual disturbances
0.782 0.218 0.000
Chapter XXII Codes for special purposes
0.782 0.218 0.000
S01.0 Open wound of scalp
0.781 0.219 0.000
Z89 Acquired absence of limb
0.781 0.219 0.000
D64.9 Anaemia, unspecified
0.781 0.219 0.000
M70.6 Trochanteric bursitis
0.780 0.220 0.000
G62 Other polyneuropathies
0.779 0.221 0.000
N64 Other disorders of breast
0.779 0.221 0.000
M23 Internal derangement of knee
0.778 0.222 0.000
O41 Other disorders of amniotic fluid and membranes
0.778 0.222 0.000
M25.9 Joint disorder, unspecified
0.778 0.222 0.000
K70 Alcoholic liver disease
0.777 0.223 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.776 0.224 0.000
K35-K38 Diseases of appendix
0.775 0.225 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.774 0.226 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.773 0.227 0.000
Z99.3 Dependence on wheelchair
0.772 0.228 0.000
Z86 Personal history of certain other diseases
0.771 0.229 0.000
Q60-Q64 Congenital malformations of the urinary system
0.769 0.230 0.000
N41 Inflammatory diseases of prostate
0.769 0.231 0.000
M25.76 Osteophyte (Lower leg)
0.769 0.231 0.000
K73 Chronic hepatitis, not elsewhere classified
0.769 0.231 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.768 0.232 0.000
N00-N08 Glomerular diseases
0.766 0.234 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.765 0.235 0.000
M25.74 Osteophyte (Hand)
0.765 0.235 0.000
N13.8 Other obstructive and reflux uropathy
0.765 0.235 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.764 0.236 0.000
Z95.2 Presence of prosthetic heart valve
0.763 0.237 0.000
J98 Other respiratory disorders
0.763 0.237 0.000
M35 Other systemic involvement of connective tissue
0.763 0.237 0.000
O40 Polyhydramnios
0.761 0.239 0.000
K74 Fibrosis and cirrhosis of liver
0.760 0.240 0.000
M77 Other enthesopathies
0.755 0.245 0.000
J42 Unspecified chronic bronchitis
0.753 0.247 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.752 0.248 0.000
S72.0 Fracture of neck of femur
0.752 0.248 0.000
Z95.4 Presence of other heart-valve replacement
0.751 0.249 0.000
J43.9 Emphysema, unspecified
0.751 0.249 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.751 0.249 0.000
O36.5 Maternal care for poor foetal growth
0.750 0.250 0.000
M25.46 Effusion of joint (Lower leg)
0.746 0.254 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.746 0.254 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.745 0.255 0.000
N76 Other inflammation of vagina and vulva
0.745 0.255 0.000
T82.3 Mechanical complication of other vascular grafts
0.744 0.256 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.743 0.257 0.000
O47.9 False labour, unspecified
0.742 0.258 0.000
L60-L75 Disorders of skin appendages
0.741 0.259 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.740 0.260 0.000
M65-M68 Disorders of synovium and tendon
0.739 0.261 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.739 0.261 0.000
K12 Stomatitis and related lesions
0.739 0.261 0.000
J20 Acute bronchitis
0.738 0.262 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.736 0.264 0.000
G40-G47 Episodic and paroxysmal disorders
0.736 0.264 0.000
M25.59 Pain in joint (Site unspecified)
0.735 0.265 0.000
L03 Cellulitis
0.734 0.266 0.000
M70.65 Trochanteric bursitis-Pelvic/Thigh
0.734 0.266 0.000
N64.1 Fat necrosis of breast
0.734 0.266 0.000
M05-M14 Inflammatory polyarthropathies
0.734 0.266 0.000
N39 Other disorders of urinary system
0.733 0.267 0.000
S01.9 Open wound of head, part unspecified
0.732 0.268 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.730 0.270 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.729 0.271 0.000
M15-M19 Arthrosis
0.729 0.271 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.729 0.271 0.000
Z84 Family history of other conditions
0.729 0.271 0.000
K76.6 Portal hypertension
0.729 0.271 0.000
S62 Fracture at wrist and hand level
0.729 0.271 0.000
N48.6 Balanitis xerotica obliterans
0.728 0.272 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.728 0.272 0.000
S40-S49 Injuries to the shoulder and upper arm
0.726 0.274 0.000
M25.56 Pain in joint (Lower leg)
0.725 0.275 0.000
N42 Other disorders of prostate
0.724 0.275 0.000
J46 Status asthmaticus
0.724 0.276 0.000
S05 Injury of eye and orbit
0.724 0.276 0.000
K13 Other diseases of lip and oral mucosa
0.723 0.277 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.722 0.278 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.721 0.279 0.000
G80 Infantile cerebral palsy
0.720 0.280 0.000
D75.8 Other specified diseases of blood and blood-forming organs
0.719 0.280 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.719 0.281 0.000
Q50-Q56 Congenital malformations of genital organs
0.718 0.281 0.000
J60-J70 Lung diseases due to external agents
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
G20 Parkinson's disease
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.716 0.283 0.000
M34 Systemic sclerosis
0.716 0.283 0.000
M33 Dermatopolymyositis
0.716 0.283 0.000
M32 Systemic lupus erythematosus
0.716 0.283 0.000
M30 Polyarteritis nodosa and related conditions
0.716 0.283 0.000
J41 Simple and mucopurulent chronic bronchitis
0.716 0.284 0.000
O48 Prolonged pregnancy
0.716 0.284 0.000
O85-O92 Complications predominantly related to the puerperium
0.716 0.284 0.000
G70-G73 Diseases of myoneural junction and muscle
0.715 0.285 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.715 0.285 0.000
M25.3 Other instability of joint
0.715 0.285 0.000
M25.2 Flail joint
0.715 0.285 0.000
M25.1 Fistula of joint
0.715 0.285 0.000
M25.0 Haemarthrosis
0.715 0.285 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.714 0.286 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.714 0.286 0.000
S64.4 Injury of digital nerve of other finger
0.714 0.286 0.000
Z94 Transplanted organ and tissue status
0.713 0.287 0.000
K01 Embedded and impacted teeth
0.713 0.287 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.713 0.287 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.713 0.287 0.000
N39.0 Urinary tract infection, site not specified
0.712 0.288 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.711 0.289 0.000
M24.0 Loose body in joint
0.710 0.290 0.000
M24.5 Contracture of joint
0.710 0.290 0.000
S69 Other and unspecified injuries of wrist and hand
0.709 0.290 0.000
O36.8 Maternal care for other specified foetal problems
0.709 0.291 0.000
D80-D89 Certain disorders involving the immune mechanism
0.708 0.292 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.708 0.292 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.707 0.293 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.707 0.293 0.000
K14 Diseases of tongue
0.706 0.294 0.000
S20-S29 Injuries to the thorax
0.706 0.294 0.000
N48.2 Other inflammatory disorders of penis
0.705 0.295 0.000
D55-D59 Haemolytic anaemias
0.705 0.295 0.000
O82 Single delivery by Caesarean section
0.704 0.296 0.000
O24 Diabetes mellitus in pregnancy
0.704 0.296 0.000
Z93.0 Tracheostomy status
0.703 0.297 0.000
T86 Failure and rejection of transplanted organs and tissues
0.702 0.298 0.000
Z92.8 Personal history of other medical treatment
0.701 0.299 0.000
O45 Premature separation of placenta [abruptio placentae]
0.701 0.299 0.000
O44 Placenta praevia
0.701 0.299 0.000
O43 Placental disorders
0.701 0.299 0.000
O33 Maternal care for known or suspected disproportion
0.701 0.299 0.000
O31 Complications specific to multiple gestation
0.701 0.299 0.000
R50-R69 General symptoms and signs
0.701 0.299 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.700 0.300 0.000
O29 Complications of anaesthesia during pregnancy
0.699 0.301 0.000
O28 Abnormal findings on antenatal screening of mother
0.699 0.301 0.000
O23 Infections of genito-urinary tract in pregnancy
0.699 0.301 0.000
O22 Venous complications in pregnancy
0.699 0.301 0.000
O21 Excessive vomiting in pregnancy
0.699 0.301 0.000
O25 Malnutrition in pregnancy
0.699 0.301 0.000
S72.4 Fracture of lower end of femur
0.699 0.301 0.000
O20.0 Threatened abortion
0.698 0.302 0.000
H00 Hordeolum and chalazion
0.698 0.302 0.000
S01.1 Open wound of eyelid and periocular area
0.697 0.303 0.000
M86-M90 Other osteopathies
0.696 0.304 0.000
K77 Liver disorders in diseases classified elsewhere
0.696 0.304 0.000
K71 Toxic liver disease
0.696 0.304 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.696 0.304 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.696 0.304 0.000
G37 Other demyelinating diseases of central nervous system
0.695 0.305 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.694 0.306 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.694 0.306 0.000
N46 Male infertility
0.694 0.306 0.000
N44 Torsion of testis
0.694 0.306 0.000
K11 Diseases of salivary glands
0.694 0.306 0.000
O30 Multiple gestation
0.693 0.307 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.693 0.307 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.691 0.309 0.000
G83 Other paralytic syndromes
0.691 0.309 0.000
M25.58 Pain in joint (Other)
0.690 0.309 0.000
M25.54 Pain in joint (Hand)
0.690 0.309 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.689 0.311 0.000
D75.2 Essential thrombocytosis
0.689 0.311 0.000
M21.3 Wrist or foot drop (acquired)
0.688 0.312 0.000
K76.7 Hepatorenal syndrome
0.688 0.312 0.000
K76.5 Hepatic veno-occlusive disease
0.688 0.312 0.000
K76.4 Peliosis hepatis
0.688 0.312 0.000
K76.3 Infarction of liver
0.688 0.312 0.000
K76.2 Central haemorrhagic necrosis of liver
0.688 0.312 0.000
K76.1 Chronic passive congestion of liver
0.688 0.312 0.000
T79-T79 Certain early complications of trauma
0.688 0.312 0.000
G30-G32 Other degenerative diseases of the nervous system
0.687 0.313 0.000
M25.71 Osteophyte (Shoulder region)
0.686 0.314 0.000
T85.2 Mechanical complication of intraocular lens
0.686 0.314 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.685 0.315 0.000
M18 Arthrosis of first carpometacarpal joint
0.685 0.315 0.000
J45 Asthma
0.684 0.316 0.000
D75.9 Disease of blood and blood-forming organs, unspecified
0.684 0.316 0.000
S72.00 Fracture of neck of femur (closed)
0.684 0.316 0.000
N25-N29 Other disorders of kidney and ureter
0.683 0.317 0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level
0.683 0.317 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.683 0.317 0.000
A30-A49 Other bacterial diseases
0.683 0.317 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.682 0.318 0.000
S65 Injury of blood vessels at wrist and hand level
0.682 0.318 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.682 0.318 0.000
S02 Fracture of skull and facial bones
0.682 0.318 0.000
Z96 Presence of other functional implants
0.681 0.319 0.000
Z93.1 Gastrostomy status
0.681 0.319 0.000
S06 Intracranial injury
0.681 0.319 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.681 0.319 0.000
T82.1 Mechanical complication of cardiac electronic device
0.680 0.320 0.000
G61.0 Guillain-Barre syndrome
0.679 0.321 0.000
L03.1 Cellulitis of other parts of limb
0.679 0.321 0.000
S60.9 Superficial injury of wrist and hand, unspecified
0.679 0.321 0.000
M25.79 Osteophyte (Site unspecified)
0.679 0.321 0.000
M25.73 Osteophyte (Forearm)
0.679 0.321 0.000
M25.72 Osteophyte (Upper arm)
0.679 0.321 0.000
M25.70 Osteophyte (Multiple sites)
0.679 0.321 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.678 0.322 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.678 0.322 0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
0.677 0.323 0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium
0.677 0.323 0.000
O26.5 Maternal hypotension syndrome
0.677 0.323 0.000
O26.4 Herpes gestationis
0.677 0.323 0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy
0.677 0.323 0.000
O26.2 Pregnancy care of habitual aborter
0.677 0.323 0.000
O26.1 Low weight gain in pregnancy
0.677 0.323 0.000
O26.0 Excessive weight gain in pregnancy
0.677 0.323 0.000
M22.8 Other disorders of patella
0.677 0.323 0.000
G63.2 Diabetic polyneuropathy
0.677 0.323 0.000
K09 Cysts of oral region, not elsewhere classified
0.676 0.324 0.000
N63 Unspecified lump in breast
0.676 0.324 0.000
M84 Disorders of continuity of bone
0.676 0.324 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.676 0.324 0.000
N15 Other renal tubulo-interstitial diseases
0.676 0.324 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.676 0.324 0.000
N11 Chronic tubulo-interstitial nephritis
0.676 0.324 0.000
N10 Acute tubulo-interstitial nephritis
0.676 0.324 0.000
Z93.5 Cystostomy status
0.675 0.325 0.000
O00-O08 Pregnancy with abortive outcome
0.675 0.325 0.000
S01.3 Open wound of ear
0.675 0.325 0.000
D73 Diseases of spleen
0.675 0.325 0.000
S72.1 Pertrochanteric fracture
0.674 0.326 0.000
M25.86 Other specified joint disorders (Lower leg)
0.673 0.327 0.000
H00.1 Chalazion
0.673 0.327 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.672 0.328 0.000
Z86.0 Personal history of other neoplasms
0.672 0.328 0.000
D68 Other coagulation defects
0.672 0.328 0.000
K75.8 Other specified inflammatory liver diseases
0.671 0.329 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.671 0.329 0.000
Q00-Q07 Congenital malformations of the nervous system
0.671 0.329 0.000
M76 Enthesopathies of lower limb, excluding foot
0.671 0.329 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.671 0.329 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.669 0.331 0.000
G62.9 Polyneuropathy, unspecified
0.668 0.332 0.000
M31 Other necrotising vasculopathies
0.668 0.332 0.000
G60 Hereditary and idiopathic neuropathy
0.667 0.332 0.000
G64 Other disorders of peripheral nervous system
0.667 0.332 0.000
M25.53 Pain in joint (Forearm)
0.667 0.333 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.667 0.333 0.000
J40 Bronchitis, not specified as acute or chronic
0.666 0.334 0.000
S67.0 Crushing injury of thumb and other finger(s)
0.666 0.334 0.000
Z89.5 Acquired absence of leg at or below knee
0.666 0.334 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.666 0.334 0.000
K04 Diseases of pulp and periapical tissues
0.665 0.335 0.000
M72.2 Plantar fascial fibromatosis
0.665 0.335 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.664 0.336 0.000
M21.0 Valgus deformity, not elsewhere classified
0.664 0.336 0.000
O47.0 False labour before 37 completed weeks of gestation
0.664 0.336 0.000
G82 Paraplegia and tetraplegia
0.662 0.337 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.662 0.338 0.000
M24.1 Other articular cartilage disorders
0.662 0.338 0.000
H54 Blindness and low vision
0.662 0.338 0.000
Z81 Family history of mental and behavioural disorders
0.661 0.338 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.661 0.339 0.000
K72 Hepatic failure, not elsewhere classified
0.660 0.340 0.000
K08 Other disorders of teeth and supporting structures
0.660 0.340 0.000
K02.9 Dental caries, unspecified
0.660 0.340 0.000
J21 Acute bronchiolitis
0.659 0.341 0.000
K82 Other diseases of gallbladder
0.659 0.341 0.000
S08 Traumatic amputation of part of head
0.659 0.341 0.000
S07 Crushing injury of head
0.659 0.341 0.000
S04 Injury of cranial nerves
0.659 0.341 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.659 0.341 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.659 0.341 0.000
N48.9 Disorder of penis, unspecified
0.657 0.342 0.000
N48.5 Ulcer of penis
0.657 0.342 0.000
N48.3 Priapism
0.657 0.342 0.000
N48.0 Leukoplakia of penis
0.657 0.342 0.000
Z99.1 Dependence on respirator
0.657 0.343 0.000
L40-L45 Papulosquamous disorders
0.657 0.343 0.000
K35 Acute appendicitis
0.657 0.343 0.000
T90 Sequelae of injuries of head
0.656 0.344 0.000
Chapter V Mental and behavioural disorders
0.656 0.344 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.655 0.345 0.000
Q80-Q89 Other congenital malformations
0.655 0.345 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.655 0.345 0.000
Q35-Q37 Cleft lip and cleft palate
0.655 0.345 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.655 0.345 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.655 0.345 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.655 0.345 0.000
D74 Methaemoglobinaemia
0.655 0.345 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.655 0.345 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.655 0.345 0.000
K10 Other diseases of jaws
0.655 0.345 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.655 0.345 0.000
K03 Other diseases of hard tissues of teeth
0.655 0.345 0.000
K00 Disorders of tooth development and eruption
0.655 0.345 0.000
Z92.9 Personal history of medical treatment, unspecified
0.654 0.345 0.000
Z92.5 Personal history of rehabilitation measures
0.654 0.345 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.654 0.346 0.000
D50 Iron deficiency anaemia
0.654 0.346 0.000
Z95.0 Presence of cardiac pacemaker
0.653 0.347 0.000
T66-T78 Other and unspecified effects of external causes
0.653 0.347 0.000
M23.4 Loose body in knee
0.652 0.348 0.000
N99-N99 Other disorders of the genitourinary system
0.651 0.349 0.000
M71 Other bursopathies
0.650 0.350 0.000
Q63 Other congenital malformations of kidney
0.650 0.350 0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy
0.649 0.350 0.000
O36.6 Maternal care for excessive foetal growth
0.649 0.350 0.000
O36.4 Maternal care for intra-uterine death
0.649 0.350 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.649 0.350 0.000
O36.2 Maternal care for hydrops foetalis
0.649 0.350 0.000
O36.1 Maternal care for other isoimmunisation
0.649 0.350 0.000
S78 Traumatic amputation of hip and thigh
0.649 0.351 0.000
S77 Crushing injury of hip and thigh
0.649 0.351 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.649 0.351 0.000
S75 Injury of blood vessels at hip and thigh level
0.649 0.351 0.000
S74 Injury of nerves at hip and thigh level
0.649 0.351 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.649 0.351 0.000
S71 Open wound of hip and thigh
0.649 0.351 0.000
N41.9 Inflammatory disease of prostate, unspecified
0.649 0.351 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.648 0.352 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.648 0.352 0.000
N13.6 Pyonephrosis
0.648 0.352 0.000
N13.4 Hydroureter
0.648 0.352 0.000
G43 Migraine
0.647 0.352 0.000
N70 Salpingitis and oophoritis
0.647 0.353 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.644 0.356 0.000
S90 Superficial injury of ankle and foot
0.642 0.358 0.000
G36 Other acute disseminated demyelination
0.641 0.359 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.641 0.359 0.000
M50-M54 Other dorsopathies
0.640 0.360 0.000
N50 Other disorders of male genital organs
0.640 0.360 0.000
K65 Peritonitis
0.640 0.360 0.000
R47-R49 Symptoms and signs involving speech and voice
0.639 0.361 0.000
S09 Other and unspecified injuries of head
0.639 0.361 0.000
B25-B34 Other viral diseases
0.638 0.362 0.000
D75.0 Familial erythrocytosis
0.637 0.363 0.000
T17 Foreign body in respiratory tract
0.637 0.363 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.636 0.363 0.000
G91 Hydrocephalus
0.636 0.364 0.000
K66 Other disorders of peritoneum
0.636 0.364 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.635 0.365 0.000
M43 Other deforming dorsopathies
0.635 0.365 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.635 0.365 0.000
G00 Bacterial meningitis, not elsewhere classified
0.634 0.366 0.000
K05 Gingivitis and periodontal diseases
0.634 0.366 0.000
R63 Symptoms and signs concerning food and fluid intake
0.634 0.366 0.000
J98.1 Pulmonary collapse
0.633 0.367 0.000
T87.4 Infection of amputation stump
0.633 0.367 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.633 0.367 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.633 0.367 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.633 0.367 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.633 0.367 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.633 0.367 0.000
K75.0 Abscess of liver
0.632 0.368 0.000
H53.1 Subjective visual disturbances
0.632 0.368 0.000
N76.4 Abscess of vulva
0.632 0.368 0.000
M25.78 Osteophyte (Other)
0.631 0.369 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.631 0.369 0.000
O42 Premature rupture of membranes
0.631 0.369 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.630 0.370 0.000
H10-H13 Disorders of conjunctiva
0.630 0.370 0.000
K70.9 Alcoholic liver disease, unspecified
0.629 0.370 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.629 0.370 0.000
S01.8 Open wound of other parts of head
0.629 0.371 0.000
S79 Other and unspecified injuries of hip and thigh
0.629 0.371 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.629 0.371 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.628 0.372 0.000
K81 Cholecystitis
0.628 0.372 0.000
N76.3 Subacute and chronic vulvitis
0.628 0.372 0.000
L50-L54 Urticaria and erythema
0.628 0.372 0.000
S52 Fracture of forearm
0.627 0.373 0.000
S70 Superficial injury of hip and thigh
0.627 0.373 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.627 0.373 0.000
K02.8 Other dental caries
0.626 0.374 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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