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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs76769018
log Bayes Factor = 23.0474
Chromosome 3   position 101,601,059  (GRCh37) Explore rs76769018 on Ensembl!
Variant rs76769018 is part of Cluster X0040

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
N17-N19 Renal failure
0.999 0.001 0.000
Chapter I Certain infectious and parasitic diseases
0.999 0.001 0.000
Chapter XIV Diseases of the genitourinary system
0.998 0.002 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.998 0.002 0.000
N17 Acute renal failure
0.998 0.002 0.000
B95-B98 Bacterial, viral and other infectious agents
0.998 0.002 0.000
N17.9 Acute renal failure, unspecified
0.997 0.003 0.000
I30-I52 Other forms of heart disease
0.996 0.004 0.000
I20-I25 Ischaemic heart diseases
0.996 0.004 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.996 0.004 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.995 0.005 0.000
E70-E90 Metabolic disorders
0.995 0.005 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.994 0.006 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.994 0.006 0.000
I60-I69 Cerebrovascular diseases
0.992 0.008 0.000
N18 Chronic renal failure
0.992 0.008 0.000
F17.1 Harmful use
0.991 0.009 0.000
M45-M49 Spondylopathies
0.991 0.009 0.000
N18.9 Chronic renal failure, unspecified
0.989 0.011 0.000
Chapter XX External causes of morbidity and mortality
0.988 0.012 0.000
M47 Spondylosis
0.987 0.013 0.000
F30-F39 Mood [affective] disorders
0.985 0.015 0.000
M47.8 Other spondylosis
0.980 0.020 0.000
I21 Acute myocardial infarction
0.973 0.027 0.000
M50-M54 Other dorsopathies
0.972 0.028 0.000
Chapter VIII Diseases of the ear and mastoid process
0.970 0.030 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.967 0.033 0.000
H65-H75 Diseases of middle ear and mastoid
0.965 0.035 0.000
I21.9 Acute myocardial infarction, unspecified
0.963 0.037 0.000
N10-N16 Renal tubulo-interstitial diseases
0.962 0.038 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.961 0.039 0.000
M47.82 Other spondylosis (Cervical region)
0.958 0.042 0.000
E86 Volume depletion
0.957 0.043 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.956 0.044 0.000
F31 Bipolar affective disorder
0.951 0.049 0.000
I49 Other cardiac arrhythmias
0.949 0.051 0.000
I63 Cerebral infarction
0.947 0.053 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.944 0.056 0.000
B35-B49 Mycoses
0.944 0.056 0.000
Chapter VI Diseases of the nervous system
0.942 0.058 0.000
Chapter VII Diseases of the eye and adnexa
0.940 0.060 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.939 0.061 0.000
S80-S89 Injuries to the knee and lower leg
0.938 0.062 0.000
M47.86 Other spondylosis (Lumbar region)
0.937 0.063 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.935 0.065 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.934 0.066 0.000
D50-D53 Nutritional anaemias
0.928 0.072 0.000
M54 Dorsalgia
0.928 0.072 0.000
F33 Recurrent depressive disorder
0.925 0.075 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.924 0.076 0.000
I34 Nonrheumatic mitral valve disorders
0.923 0.077 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.919 0.081 0.000
K70-K77 Diseases of liver
0.915 0.085 0.000
Chapter XI Diseases of the digestive system
0.913 0.087 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.912 0.088 0.000
M54.5 Low back pain
0.910 0.090 0.000
I42 Cardiomyopathy
0.909 0.091 0.000
B15-B19 Viral hepatitis
0.904 0.096 0.000
W00-W19 Falls
0.902 0.098 0.000
B37 Candidiasis
0.901 0.099 0.000
F31.9 Bipolar affective disorder, unspecified
0.898 0.102 0.000
D50 Iron deficiency anaemia
0.896 0.104 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.895 0.105 0.000
M86-M90 Other osteopathies
0.894 0.106 0.000
H72 Perforation of tympanic membrane
0.892 0.108 0.000
Chapter XXII Codes for special purposes
0.892 0.108 0.000
I51 Complications and ill-defined descriptions of heart disease
0.890 0.110 0.000
M54.59 Low back pain (Site unspecified)
0.890 0.110 0.000
E87.2 Acidosis
0.889 0.111 0.000
D50.9 Iron deficiency anaemia, unspecified
0.889 0.111 0.000
F10.2 Dependence syndrome
0.887 0.113 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.884 0.116 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.884 0.116 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.884 0.116 0.000
I25 Chronic ischaemic heart disease
0.884 0.116 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.881 0.119 0.000
I85 Oesophageal varices
0.880 0.120 0.000
S82 Fracture of lower leg, including ankle
0.880 0.120 0.000
G90-G99 Other disorders of the nervous system
0.879 0.121 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.877 0.123 0.000
K74 Fibrosis and cirrhosis of liver
0.869 0.131 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.868 0.132 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.867 0.133 0.000
I80 Phlebitis and thrombophlebitis
0.867 0.133 0.000
K70 Alcoholic liver disease
0.867 0.133 0.000
I49.3 Ventricular premature depolarisation
0.866 0.134 0.000
I34.0 Mitral (valve) insufficiency
0.865 0.135 0.000
K76 Other diseases of liver
0.864 0.136 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.861 0.139 0.000
H10-H13 Disorders of conjunctiva
0.859 0.141 0.000
I22 Subsequent myocardial infarction
0.858 0.142 0.000
H74 Other disorders of middle ear and mastoid
0.858 0.142 0.000
H71 Cholesteatoma of middle ear
0.853 0.147 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.850 0.150 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.850 0.150 0.000
M50 Cervical disk disorders
0.847 0.153 0.000
I25.2 Old myocardial infarction
0.847 0.153 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.846 0.154 0.000
K74.6 Other and unspecified cirrhosis of liver
0.846 0.154 0.000
V10-V19 Pedal cyclist injured in transport accident
0.842 0.158 0.000
N18.0 End-stage renal disease
0.838 0.162 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.836 0.164 0.000
M40-M43 Deforming dorsopathies
0.834 0.166 0.000
I86 Varicose veins of other sites
0.833 0.167 0.000
R29.6 Tendency to fall, not elsewhere classified
0.830 0.170 0.000
I24 Other acute ischaemic heart diseases
0.830 0.170 0.000
I36 Nonrheumatic tricuspid valve disorders
0.827 0.173 0.000
M47.1 Other spondylosis with myelopathy
0.824 0.175 0.000
N19 Unspecified renal failure
0.824 0.176 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.822 0.178 0.000
I85.9 Oesophageal varices without bleeding
0.822 0.178 0.000
I51.7 Cardiomegaly
0.822 0.178 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.822 0.178 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.821 0.179 0.000
S00-S09 Injuries to the head
0.820 0.180 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.820 0.180 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.819 0.181 0.000
T79-T79 Certain early complications of trauma
0.818 0.182 0.000
I95 Hypotension
0.817 0.183 0.000
Y52 Agents primarily affecting the cardiovascular system
0.813 0.187 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.813 0.187 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.812 0.188 0.000
E83 Disorders of mineral metabolism
0.811 0.189 0.000
M54.56 Low back pain (Lumbar region)
0.810 0.190 0.000
E87.3 Alkalosis
0.809 0.191 0.000
S70-S79 Injuries to the hip and thigh
0.808 0.192 0.000
N00-N08 Glomerular diseases
0.807 0.193 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.807 0.193 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.807 0.193 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.806 0.194 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.805 0.195 0.000
E73 Lactose intolerance
0.805 0.195 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.803 0.197 0.000
I61 Intracerebral haemorrhage
0.803 0.197 0.000
I60 Subarachnoid haemorrhage
0.802 0.197 0.000
G20-G26 Extrapyramidal and movement disorders
0.802 0.198 0.000
I46 Cardiac arrest
0.802 0.198 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.797 0.203 0.000
I49.0 Ventricular fibrillation and flutter
0.797 0.203 0.000
H11 Other disorders of conjunctiva
0.796 0.204 0.000
N17.0 Acute renal failure with tubular necrosis
0.796 0.204 0.000
K70.9 Alcoholic liver disease, unspecified
0.794 0.206 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.794 0.206 0.000
M80-M85 Disorders of bone density and structure
0.792 0.208 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.792 0.208 0.000
E87.0 Hyperosmolality and hypernatraemia
0.791 0.209 0.000
B37.4 Candidiasis of other urogenital sites
0.789 0.211 0.000
H65 Nonsuppurative otitis media
0.788 0.212 0.000
I25.3 Aneurysm of heart
0.787 0.213 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.786 0.214 0.000
E87.5 Hyperkalaemia
0.786 0.214 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.784 0.216 0.000
M70-M79 Other soft tissue disorders
0.784 0.216 0.000
S82.6 Fracture of lateral malleolus
0.782 0.218 0.000
N18.4 Chronic kidney disease, stage 4
0.781 0.219 0.000
I71 Aortic aneurysm and dissection
0.781 0.219 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.780 0.220 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.777 0.223 0.000
E85 Amyloidosis
0.777 0.223 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.777 0.223 0.000
N15 Other renal tubulo-interstitial diseases
0.774 0.226 0.000
H73 Other disorders of tympanic membrane
0.773 0.227 0.000
I42.0 Dilated cardiomyopathy
0.773 0.227 0.000
I63.8 Other cerebral infarction
0.772 0.228 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.769 0.231 0.000
D51 Vitamin B12 deficiency anaemia
0.769 0.231 0.000
I69 Sequelae of cerebrovascular disease
0.769 0.231 0.000
I47 Paroxysmal tachycardia
0.766 0.234 0.000
H04 Disorders of lachrymal system
0.766 0.234 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.766 0.234 0.000
E10-E14 Diabetes mellitus
0.765 0.235 0.000
K76.6 Portal hypertension
0.765 0.235 0.000
F99-F99 Unspecified mental disorder
0.764 0.236 0.000
H69 Other disorders of Eustachian tube
0.764 0.236 0.000
M00-M03 Infectious arthropathies
0.764 0.236 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.764 0.236 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.763 0.237 0.000
M47.9 Spondylosis, unspecified
0.763 0.237 0.000
F60-F69 Disorders of adult personality and behaviour
0.761 0.239 0.000
B18 Chronic viral hepatitis
0.760 0.240 0.000
K72 Hepatic failure, not elsewhere classified
0.759 0.241 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.759 0.241 0.000
Y48 Anaesthetics and therapeutic gases
0.757 0.243 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.757 0.243 0.000
F33.9 Recurrent depressive disorder, unspecified
0.757 0.243 0.000
I49.8 Other specified cardiac arrhythmias
0.757 0.243 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.755 0.245 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.754 0.246 0.000
B37.9 Candidiasis, unspecified
0.754 0.246 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.754 0.246 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.753 0.247 0.000
R26 Abnormalities of gait and mobility
0.751 0.249 0.000
E87.6 Hypokalaemia
0.751 0.249 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.751 0.249 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.750 0.250 0.000
I95.9 Hypotension, unspecified
0.750 0.250 0.000
M60-M63 Disorders of muscles
0.749 0.251 0.000
I10-I15 Hypertensive diseases
0.749 0.251 0.000
M47.2 Other spondylosis with radiculopathy
0.749 0.251 0.000
X60-X84 Intentional self-harm
0.749 0.251 0.000
I62 Other nontraumatic intracranial haemorrhage
0.748 0.252 0.000
I49.1 Atrial premature depolarisation
0.748 0.252 0.000
I45 Other conduction disorders
0.748 0.252 0.000
I65.2 Occlusion and stenosis of carotid artery
0.748 0.252 0.000
H72.0 Central perforation of tympanic membrane
0.748 0.252 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.747 0.253 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.747 0.253 0.000
T91 Sequelae of injuries of neck and trunk
0.747 0.253 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.747 0.253 0.000
S80 Superficial injury of lower leg
0.746 0.254 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.744 0.256 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.744 0.256 0.000
I86.4 Gastric varices
0.744 0.256 0.000
M50.3 Other cervical disk degeneration
0.744 0.256 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.743 0.257 0.000
R94 Abnormal results of function studies
0.743 0.257 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.742 0.258 0.000
I72 Other aneurysm
0.742 0.258 0.000
I87 Other disorders of veins
0.742 0.258 0.000
H00 Hordeolum and chalazion
0.742 0.258 0.000
V80-V89 Other land transport accidents
0.741 0.259 0.000
M89 Other disorders of bone
0.739 0.261 0.000
M87 Osteonecrosis
0.739 0.261 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.739 0.261 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.737 0.263 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.737 0.263 0.000
M54.4 Lumbago with sciatica
0.737 0.263 0.000
W10 Fall on and from stairs and steps
0.736 0.264 0.000
F80-F89 Disorders of psychological development
0.735 0.265 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.734 0.266 0.000
G40-G47 Episodic and paroxysmal disorders
0.734 0.266 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.733 0.267 0.000
X50-X57 Overexertion, travel and privation
0.732 0.267 0.000
E40-E46 Malnutrition
0.732 0.268 0.000
I49.5 Sick sinus syndrome
0.731 0.269 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.728 0.272 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.728 0.272 0.000
B37.3 Candidiasis of vulva and vagina
0.727 0.273 0.000
T66-T78 Other and unspecified effects of external causes
0.726 0.274 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.725 0.275 0.000
G90 Disorders of autonomic nervous system
0.724 0.276 0.000
H11.0 Pterygium
0.722 0.278 0.000
F17.2 Dependence syndrome
0.721 0.279 0.000
I82 Other venous embolism and thrombosis
0.721 0.279 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.720 0.280 0.000
S82.3 Fracture of lower end of tibia
0.720 0.280 0.000
S90-S99 Injuries to the ankle and foot
0.720 0.280 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.720 0.280 0.000
E83.1 Disorders of iron metabolism
0.719 0.281 0.000
M51 Other intervertebral disk disorders
0.719 0.281 0.000
S10-S19 Injuries to the neck
0.718 0.282 0.000
S20-S29 Injuries to the thorax
0.718 0.282 0.000
I50 Heart failure
0.718 0.282 0.000
B16 Acute hepatitis B
0.718 0.282 0.000
W07 Fall involving chair
0.717 0.283 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.717 0.283 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
B99-B99 Other infectious diseases
0.716 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.716 0.283 0.000
B65-B83 Helminthiases
0.716 0.283 0.000
B50-B64 Protozoal diseases
0.716 0.283 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.716 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.716 0.283 0.000
A80-A89 Viral infections of the central nervous system
0.716 0.283 0.000
A75-A79 Rickettsioses
0.716 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.716 0.283 0.000
A65-A69 Other spirochaetal diseases
0.716 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.716 0.283 0.000
A15-A19 Tuberculosis
0.716 0.283 0.000
I67 Other cerebrovascular diseases
0.716 0.284 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.716 0.284 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.716 0.284 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.716 0.284 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.716 0.284 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.716 0.284 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.716 0.284 0.000
F11 Mental and behavioural disorders due to use of opioids
0.716 0.284 0.000
N17.8 Other acute renal failure
0.716 0.284 0.000
N17.2 Acute renal failure with medullary necrosis
0.716 0.284 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.716 0.284 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.716 0.284 0.000
M91-M94 Chondropathies
0.715 0.285 0.000
M86 Osteomyelitis
0.714 0.286 0.000
I52 Other heart disorders in diseases classified elsewhere
0.714 0.286 0.000
I48 Atrial fibrillation and flutter
0.714 0.286 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.714 0.286 0.000
I41 Myocarditis in diseases classified elsewhere
0.714 0.286 0.000
I40 Acute myocarditis
0.714 0.286 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.714 0.286 0.000
I37 Pulmonary valve disorders
0.714 0.286 0.000
I32 Pericarditis in diseases classified elsewhere
0.714 0.286 0.000
I30 Acute pericarditis
0.714 0.286 0.000
I23 Certain current complications following acute myocardial infarction
0.714 0.286 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.714 0.286 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.714 0.286 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.714 0.286 0.000
H30-H36 Disorders of choroid and retina
0.714 0.286 0.000
E11 Non-insulin-dependent diabetes mellitus
0.714 0.286 0.000
E84 Cystic fibrosis
0.713 0.287 0.000
E79 Disorders of purine and pyrimidine metabolism
0.713 0.287 0.000
E77 Disorders of glycoprotein metabolism
0.713 0.287 0.000
E76 Disorders of glycosaminoglycan metabolism
0.713 0.287 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.713 0.287 0.000
E74 Other disorders of carbohydrate metabolism
0.713 0.287 0.000
E72 Other disorders of amino-acid metabolism
0.713 0.287 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.713 0.287 0.000
E70 Disorders of aromatic amino-acid metabolism
0.713 0.287 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.713 0.287 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.713 0.287 0.000
F17.9 Unspecified mental and behavioural disorder
0.712 0.287 0.000
F17.8 Other mental and behavioural disorders
0.712 0.287 0.000
F17.7 Residual and late-onset psychotic disorder
0.712 0.287 0.000
F17.6 Amnesic syndrome
0.712 0.287 0.000
F17.5 Psychotic disorder
0.712 0.287 0.000
F17.4 Withdrawal state with delirium
0.712 0.287 0.000
F17.3 Withdrawal state
0.712 0.287 0.000
F17.0 Acute intoxication
0.712 0.287 0.000
T33-T35 Frostbite
0.712 0.287 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.712 0.287 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.712 0.287 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.712 0.287 0.000
T00-T07 Injuries involving multiple body regions
0.712 0.287 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.712 0.288 0.000
S82.60 Fracture of lateral malleolus (closed)
0.712 0.288 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.712 0.288 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.712 0.288 0.000
N18.8 Other chronic renal failure
0.711 0.289 0.000
N18.1 Chronic kidney disease, stage 1
0.711 0.289 0.000
S40-S49 Injuries to the shoulder and upper arm
0.711 0.289 0.000
W18 Other fall on same level
0.711 0.289 0.000
M49 Spondylopathies in diseases classified elsewhere
0.710 0.290 0.000
H74.0 Tympanosclerosis
0.710 0.290 0.000
I78 Diseases of capillaries
0.709 0.291 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.708 0.292 0.000
E78.0 Pure hypercholesterolaemia
0.708 0.292 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.708 0.292 0.000
Y35-Y36 Legal intervention and operations of war
0.708 0.292 0.000
Y10-Y34 Event of undetermined intent
0.708 0.292 0.000
Y00-Y09 Assault
0.708 0.292 0.000
X85-X99 Assault
0.708 0.292 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.708 0.292 0.000
X30-X39 Exposure to forces of nature
0.708 0.292 0.000
X20-X29 Contact with venomous animals and plants
0.708 0.292 0.000
X10-X19 Contact with heat and hot substances
0.708 0.292 0.000
X00-X09 Exposure to smoke, fire and flames
0.708 0.292 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.708 0.292 0.000
W75-W84 Other accidental threats to breathing
0.708 0.292 0.000
W65-W74 Accidental drowning and submersion
0.708 0.292 0.000
W50-W64 Exposure to animate mechanical forces
0.708 0.292 0.000
V98-V99 Other and unspecified transport accidents
0.708 0.292 0.000
V95-V97 Air and space transport accidents
0.708 0.292 0.000
V90-V94 Water transport accidents
0.708 0.292 0.000
V70-V79 Bus occupant injured in transport accident
0.708 0.292 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.708 0.292 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.708 0.292 0.000
V40-V49 Car occupant injured in transport accident
0.708 0.292 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.708 0.292 0.000
V01-V09 Pedestrian injured in transport accident
0.708 0.292 0.000
M47.12 Other spondylosis with myelopathy (Cervical region)
0.708 0.292 0.000
S82.8 Fractures of other parts of lower leg
0.708 0.292 0.000
Y40 Systemic antibiotics
0.708 0.292 0.000
D60-D64 Aplastic and other anaemias
0.708 0.292 0.000
H04.1 Other disorders of lachrymal gland
0.708 0.292 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.707 0.292 0.000
K70.1 Alcoholic hepatitis
0.707 0.293 0.000
F38 Other mood [affective] disorders
0.706 0.294 0.000
F34 Persistent mood [affective] disorders
0.706 0.294 0.000
F30 Manic episode
0.706 0.294 0.000
F39 Unspecified mood [affective] disorder
0.706 0.294 0.000
I42.2 Other hypertrophic cardiomyopathy
0.705 0.295 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.705 0.295 0.000
S82.4 Fracture of fibula alone
0.705 0.295 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.705 0.295 0.000
F10.0 Acute intoxication
0.703 0.297 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.703 0.297 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.703 0.297 0.000
M47.84 Other spondylosis (Thoracic region)
0.703 0.297 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.703 0.297 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.703 0.297 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.703 0.297 0.000
M05-M14 Inflammatory polyarthropathies
0.702 0.298 0.000
H05 Disorders of orbit
0.700 0.300 0.000
T36 Poisoning by systemic antibiotics
0.700 0.300 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.700 0.300 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.700 0.300 0.000
B15 Acute hepatitis A
0.699 0.301 0.000
I31 Other diseases of pericardium
0.699 0.301 0.000
I42.9 Cardiomyopathy, unspecified
0.699 0.301 0.000
G70-G73 Diseases of myoneural junction and muscle
0.698 0.302 0.000
B17 Other acute viral hepatitis
0.698 0.302 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.698 0.302 0.000
H01 Other inflammation of eyelid
0.698 0.302 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.698 0.302 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.698 0.302 0.000
E88 Other metabolic disorders
0.697 0.303 0.000
E20-E35 Disorders of other endocrine glands
0.696 0.303 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.696 0.304 0.000
W20-W49 Exposure to inanimate mechanical forces
0.696 0.304 0.000
I20 Angina pectoris
0.696 0.304 0.000
K04 Diseases of pulp and periapical tissues
0.696 0.304 0.000
H74.3 Other acquired abnormalities of ear ossicles
0.695 0.304 0.000
K65-K67 Diseases of peritoneum
0.695 0.305 0.000
B44 Aspergillosis
0.694 0.306 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.694 0.306 0.000
E87.4 Mixed disorder of acid-base balance
0.694 0.306 0.000
E50-E64 Other nutritional deficiencies
0.693 0.307 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.693 0.307 0.000
B37.0 Candidal stomatitis
0.693 0.307 0.000
S81 Open wound of lower leg
0.693 0.307 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.692 0.308 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.692 0.308 0.000
H70 Mastoiditis and related conditions
0.692 0.308 0.000
H68 Eustachian salpingitis and obstruction
0.692 0.308 0.000
H67 Otitis media in diseases classified elsewhere
0.692 0.308 0.000
M48 Other spondylopathies
0.692 0.308 0.000
N20-N23 Urolithiasis
0.692 0.308 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.691 0.309 0.000
I12 Hypertensive renal disease
0.691 0.309 0.000
G95 Other diseases of spinal cord
0.691 0.309 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.691 0.309 0.000
G25 Other extrapyramidal and movement disorders
0.690 0.310 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.690 0.310 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.690 0.310 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.690 0.310 0.000
N11 Chronic tubulo-interstitial nephritis
0.690 0.310 0.000
M47.89 Other spondylosis (Site unspecified)
0.689 0.311 0.000
I51.4 Myocarditis, unspecified
0.689 0.311 0.000
I05-I09 Chronic rheumatic heart diseases
0.689 0.311 0.000
I88 Nonspecific lymphadenitis
0.689 0.311 0.000
K14 Diseases of tongue
0.688 0.312 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.687 0.313 0.000
I46.0 Cardiac arrest with successful resuscitation
0.687 0.313 0.000
I33 Acute and subacute endocarditis
0.686 0.314 0.000
D55-D59 Haemolytic anaemias
0.685 0.315 0.000
I42.8 Other cardiomyopathies
0.685 0.315 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.685 0.315 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.684 0.315 0.000
B37.8 Candidiasis of other sites
0.684 0.316 0.000
R94.5 Abnormal results of liver function studies
0.684 0.316 0.000
I34.1 Mitral (valve) prolapse
0.684 0.316 0.000
W13 Fall from, out of or through building or structure
0.684 0.316 0.000
K11 Diseases of salivary glands
0.683 0.317 0.000
F31.8 Other bipolar affective disorders
0.682 0.318 0.000
F31.7 Bipolar affective disorder, currently in remission
0.682 0.318 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.682 0.318 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.682 0.318 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.681 0.319 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.681 0.319 0.000
I49.2 Junctional premature depolarisation
0.680 0.320 0.000
I63.9 Cerebral infarction, unspecified
0.680 0.320 0.000
W19 Unspecified fall
0.679 0.321 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.679 0.321 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.679 0.321 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.679 0.321 0.000
Y54.5 Other diuretics
0.678 0.322 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.678 0.322 0.000
H55-H59 Other disorders of eye and adnexa
0.678 0.322 0.000
M53 Other dorsopathies, not elsewhere classified
0.677 0.323 0.000
M84 Disorders of continuity of bone
0.677 0.323 0.000
U89 Agent resistant to other and unspecified antibiotics
0.677 0.323 0.000
B48 Other mycoses, not elsewhere classified
0.677 0.323 0.000
B47 Mycetoma
0.677 0.323 0.000
B46 Zygomycosis
0.677 0.323 0.000
B45 Cryptococcosis
0.677 0.323 0.000
B43 Chromomycosis and phaeomycotic abscess
0.677 0.323 0.000
B42 Sporotrichosis
0.677 0.323 0.000
B41 Paracoccidioidomycosis
0.677 0.323 0.000
B40 Blastomycosis
0.677 0.323 0.000
B39 Histoplasmosis
0.677 0.323 0.000
B38 Coccidioidomycosis
0.677 0.323 0.000
B36 Other superficial mycoses
0.677 0.323 0.000
B35 Dermatophytosis
0.677 0.323 0.000
B49 Unspecified mycosis
0.677 0.323 0.000
T16 Foreign body in ear
0.676 0.324 0.000
I99 Other and unspecified disorders of circulatory system
0.676 0.324 0.000
R27 Other lack of coordination
0.676 0.324 0.000
R94.4 Abnormal results of kidney function studies
0.675 0.325 0.000
M41 Scoliosis
0.674 0.326 0.000
W08 Fall involving other furniture
0.674 0.326 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.674 0.326 0.000
S88 Traumatic amputation of lower leg
0.673 0.327 0.000
S87 Crushing injury of lower leg
0.673 0.327 0.000
S86 Injury of muscle and tendon at lower leg level
0.673 0.327 0.000
S85 Injury of blood vessels at lower leg level
0.673 0.327 0.000
S84 Injury of nerves at lower leg level
0.673 0.327 0.000
M54.1 Radiculopathy
0.673 0.327 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.673 0.327 0.000
M46 Other inflammatory spondylopathies
0.672 0.327 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.672 0.328 0.000
I81 Portal vein thrombosis
0.672 0.328 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.671 0.329 0.000
H11.9 Disorder of conjunctiva, unspecified
0.670 0.330 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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