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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs76775795
log Bayes Factor = 13.6666
Chromosome 12   position 115,385,431  (GRCh37) Explore rs76775795 on Ensembl!
Variant rs76775795 is part of Cluster X0021

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
0.998 0.002 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.996 0.004 0.000
Chapter XX External causes of morbidity and mortality
0.996 0.004 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.985 0.015 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.984 0.016 0.000
Chapter IX Diseases of the circulatory system
0.983 0.017 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.979 0.021 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.977 0.023 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.973 0.027 0.000
N17.9 Acute renal failure, unspecified
0.967 0.033 0.000
N17 Acute renal failure
0.963 0.037 0.000
A00-A09 Intestinal infectious diseases
0.963 0.037 0.000
Chapter X Diseases of the respiratory system
0.963 0.037 0.000
L82 Seborrhoeic keratosis
0.962 0.038 0.000
N17-N19 Renal failure
0.961 0.039 0.000
Chapter XIV Diseases of the genitourinary system
0.958 0.042 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.953 0.047 0.000
D69 Purpura and other haemorrhagic conditions
0.953 0.047 0.000
S40-S49 Injuries to the shoulder and upper arm
0.952 0.048 0.000
J09-J18 Influenza and pneumonia
0.950 0.050 0.000
S50-S59 Injuries to the elbow and forearm
0.947 0.053 0.000
W00-W19 Falls
0.940 0.060 0.000
J18 Pneumonia, organism unspecified
0.937 0.063 0.000
J40-J47 Chronic lower respiratory diseases
0.932 0.068 0.000
D60-D64 Aplastic and other anaemias
0.931 0.069 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.929 0.071 0.000
J18.1 Lobar pneumonia, unspecified
0.928 0.072 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.922 0.078 0.000
I20-I25 Ischaemic heart diseases
0.919 0.081 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.917 0.083 0.000
T93 Sequelae of injuries of lower limb
0.914 0.086 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.902 0.098 0.000
B35-B49 Mycoses
0.902 0.098 0.000
N18 Chronic renal failure
0.899 0.101 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.896 0.104 0.000
Chapter XXI Factors influencing health status and contact with health services
0.895 0.105 0.000
L89 Decubitus ulcer
0.892 0.108 0.000
J44 Other chronic obstructive pulmonary disease
0.890 0.110 0.000
T92 Sequelae of injuries of upper limb
0.888 0.112 0.000
S80-S89 Injuries to the knee and lower leg
0.888 0.112 0.000
I20 Angina pectoris
0.884 0.116 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.880 0.120 0.000
D69.6 Thrombocytopenia, unspecified
0.879 0.121 0.000
Q60-Q64 Congenital malformations of the urinary system
0.879 0.121 0.000
S40 Superficial injury of shoulder and upper arm
0.876 0.124 0.000
S52 Fracture of forearm
0.875 0.125 0.000
I77 Other disorders of arteries and arterioles
0.875 0.125 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.873 0.127 0.000
Chapter XXII Codes for special purposes
0.871 0.129 0.000
E20-E35 Disorders of other endocrine glands
0.871 0.129 0.000
S60-S69 Injuries to the wrist and hand
0.870 0.130 0.000
A30-A49 Other bacterial diseases
0.869 0.131 0.000
I71 Aortic aneurysm and dissection
0.869 0.131 0.000
J43 Emphysema
0.868 0.132 0.000
A04 Other bacterial intestinal infections
0.868 0.132 0.000
T66-T78 Other and unspecified effects of external causes
0.864 0.136 0.000
S32 Fracture of lumbar spine and pelvis
0.856 0.144 0.000
Chapter VI Diseases of the nervous system
0.847 0.153 0.000
L50-L54 Urticaria and erythema
0.847 0.153 0.000
J18.0 Bronchopneumonia, unspecified
0.847 0.153 0.000
S42 Fracture of shoulder and upper arm
0.846 0.154 0.000
A08 Viral and other specified intestinal infections
0.845 0.155 0.000
S10-S19 Injuries to the neck
0.845 0.155 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.844 0.156 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.844 0.156 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.844 0.156 0.000
I78 Diseases of capillaries
0.843 0.157 0.000
I73 Other peripheral vascular diseases
0.843 0.157 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.843 0.157 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.837 0.163 0.000
I74 Arterial embolism and thrombosis
0.830 0.170 0.000
D64 Other anaemias
0.829 0.171 0.000
E10-E14 Diabetes mellitus
0.827 0.173 0.000
L89.1 Stage II decubitus ulcer
0.827 0.173 0.000
S00-S09 Injuries to the head
0.825 0.175 0.000
S52.0 Fracture of upper end of ulna
0.825 0.175 0.000
B37 Candidiasis
0.823 0.177 0.000
I60-I69 Cerebrovascular diseases
0.823 0.177 0.000
D50-D53 Nutritional anaemias
0.822 0.178 0.000
J43.9 Emphysema, unspecified
0.822 0.178 0.000
D68 Other coagulation defects
0.822 0.178 0.000
E27 Other disorders of adrenal gland
0.821 0.179 0.000
S70-S79 Injuries to the hip and thigh
0.817 0.183 0.000
M20-M25 Other joint disorders
0.815 0.185 0.000
Q61 Cystic kidney disease
0.814 0.186 0.000
W18 Other fall on same level
0.809 0.191 0.000
I72 Other aneurysm
0.808 0.192 0.000
V10-V19 Pedal cyclist injured in transport accident
0.806 0.194 0.000
L84 Corns and callosities
0.806 0.194 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.806 0.194 0.000
L57.0 Actinic keratosis
0.805 0.195 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.804 0.195 0.000
I77.1 Stricture of artery
0.804 0.196 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.804 0.196 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.804 0.196 0.000
B15-B19 Viral hepatitis
0.803 0.197 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.799 0.201 0.000
X60-X84 Intentional self-harm
0.799 0.201 0.000
N18.9 Chronic renal failure, unspecified
0.798 0.202 0.000
I20.8 Other forms of angina pectoris
0.797 0.203 0.000
W07 Fall involving chair
0.796 0.204 0.000
D69.5 Secondary thrombocytopenia
0.796 0.204 0.000
S32.5 Fracture of pubis
0.792 0.208 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.792 0.208 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.791 0.209 0.000
S52.00 Fracture of upper end of ulna (closed)
0.789 0.211 0.000
S86 Injury of muscle and tendon at lower leg level
0.786 0.214 0.000
N75 Diseases of Bartholin's gland
0.785 0.215 0.000
S50 Superficial injury of forearm
0.784 0.215 0.000
T90 Sequelae of injuries of head
0.783 0.217 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.780 0.220 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.780 0.220 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.778 0.222 0.000
D62 Acute posthaemorrhagic anaemia
0.778 0.222 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.777 0.222 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.775 0.225 0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified
0.775 0.225 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.775 0.225 0.000
A80-A89 Viral infections of the central nervous system
0.775 0.225 0.000
T98 Sequelae of other and unspecified effects of external causes
0.774 0.225 0.000
W19 Unspecified fall
0.774 0.226 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.773 0.227 0.000
M05-M14 Inflammatory polyarthropathies
0.771 0.229 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.770 0.230 0.000
T93.0 Sequelae of open wound of lower limb
0.770 0.230 0.000
T91 Sequelae of injuries of neck and trunk
0.769 0.231 0.000
S56 Injury of muscle and tendon at forearm level
0.769 0.231 0.000
L93 Lupus erythematosus
0.769 0.231 0.000
J45 Asthma
0.769 0.231 0.000
W20-W49 Exposure to inanimate mechanical forces
0.768 0.232 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.768 0.232 0.000
Y57 Other and unspecified drugs and medicaments
0.767 0.233 0.000
X50-X57 Overexertion, travel and privation
0.766 0.234 0.000
A08.4 Viral intestinal infection, unspecified
0.765 0.235 0.000
I73.9 Peripheral vascular disease, unspecified
0.764 0.236 0.000
A04.5 Campylobacter enteritis
0.761 0.239 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.761 0.239 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.761 0.239 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.760 0.240 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.759 0.241 0.000
M21 Other acquired deformities of limbs
0.759 0.241 0.000
I20.0 Unstable angina
0.758 0.242 0.000
N76 Other inflammation of vagina and vulva
0.758 0.242 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.758 0.242 0.000
B99-B99 Other infectious diseases
0.758 0.242 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.756 0.244 0.000
I67 Other cerebrovascular diseases
0.756 0.244 0.000
D64.9 Anaemia, unspecified
0.755 0.245 0.000
N18.3 Chronic kidney disease, stage 3
0.755 0.245 0.000
I24 Other acute ischaemic heart diseases
0.753 0.247 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.753 0.247 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.751 0.249 0.000
E11 Non-insulin-dependent diabetes mellitus
0.750 0.250 0.000
I22 Subsequent myocardial infarction
0.749 0.251 0.000
L83 Acanthosis nigricans
0.747 0.253 0.000
G30-G32 Other degenerative diseases of the nervous system
0.747 0.253 0.000
S32.50 Fracture of pubis (closed)
0.746 0.254 0.000
V40-V49 Car occupant injured in transport accident
0.745 0.254 0.000
N00-N08 Glomerular diseases
0.743 0.257 0.000
E50-E64 Other nutritional deficiencies
0.742 0.258 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.740 0.260 0.000
S40.0 Contusion of shoulder and upper arm
0.740 0.260 0.000
Q00-Q07 Congenital malformations of the nervous system
0.739 0.261 0.000
S02 Fracture of skull and facial bones
0.739 0.261 0.000
W10 Fall on and from stairs and steps
0.738 0.262 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.737 0.263 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.737 0.263 0.000
D61 Other aplastic anaemias
0.735 0.264 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.735 0.265 0.000
Z13 Special screening examination for other diseases and disorders
0.735 0.265 0.000
S64 Injury of nerves at wrist and hand level
0.735 0.265 0.000
S80 Superficial injury of lower leg
0.735 0.265 0.000
Y95 Nosocomial condition
0.733 0.267 0.000
T79-T79 Certain early complications of trauma
0.733 0.267 0.000
Q61.3 Polycystic kidney, unspecified
0.731 0.269 0.000
E27.1 Primary adrenocortical insufficiency
0.729 0.271 0.000
N18.5 Chronic kidney disease, stage 5
0.728 0.272 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.728 0.272 0.000
B95-B98 Bacterial, viral and other infectious agents
0.727 0.273 0.000
B37.8 Candidiasis of other sites
0.725 0.275 0.000
S81 Open wound of lower leg
0.725 0.275 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.725 0.275 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.724 0.276 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.722 0.278 0.000
S42.0 Fracture of clavicle
0.722 0.278 0.000
M86-M90 Other osteopathies
0.722 0.278 0.000
T78 Adverse effects, not elsewhere classified
0.721 0.279 0.000
Chapter VIII Diseases of the ear and mastoid process
0.720 0.280 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.720 0.280 0.000
M50-M54 Other dorsopathies
0.720 0.280 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T92.8 Sequelae of other specified injuries of upper limb
0.717 0.283 0.000
W18.3 Sports and athletics area
0.716 0.284 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.716 0.284 0.000
J95-J99 Other diseases of the respiratory system
0.716 0.284 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.716 0.284 0.000
B65-B83 Helminthiases
0.716 0.284 0.000
B50-B64 Protozoal diseases
0.716 0.284 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.716 0.284 0.000
A75-A79 Rickettsioses
0.716 0.284 0.000
A70-A74 Other diseases caused by chlamydiae
0.716 0.284 0.000
A65-A69 Other spirochaetal diseases
0.716 0.284 0.000
A20-A28 Certain zoonotic bacterial diseases
0.716 0.284 0.000
A15-A19 Tuberculosis
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.715 0.285 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.714 0.285 0.000
V20-V29 Motorcycle rider injured in transport accident
0.714 0.286 0.000
D55-D59 Haemolytic anaemias
0.714 0.286 0.000
Y35-Y36 Legal intervention and operations of war
0.714 0.286 0.000
Y10-Y34 Event of undetermined intent
0.714 0.286 0.000
Y00-Y09 Assault
0.714 0.286 0.000
X85-X99 Assault
0.714 0.286 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.714 0.286 0.000
X30-X39 Exposure to forces of nature
0.714 0.286 0.000
X20-X29 Contact with venomous animals and plants
0.714 0.286 0.000
X10-X19 Contact with heat and hot substances
0.714 0.286 0.000
X00-X09 Exposure to smoke, fire and flames
0.714 0.286 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.714 0.286 0.000
W75-W84 Other accidental threats to breathing
0.714 0.286 0.000
W65-W74 Accidental drowning and submersion
0.714 0.286 0.000
W50-W64 Exposure to animate mechanical forces
0.714 0.286 0.000
V98-V99 Other and unspecified transport accidents
0.714 0.286 0.000
V95-V97 Air and space transport accidents
0.714 0.286 0.000
V90-V94 Water transport accidents
0.714 0.286 0.000
V80-V89 Other land transport accidents
0.714 0.286 0.000
V70-V79 Bus occupant injured in transport accident
0.714 0.286 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.714 0.286 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.714 0.286 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.714 0.286 0.000
V01-V09 Pedestrian injured in transport accident
0.714 0.286 0.000
S86.8 Injury of other muscles and tendons at lower leg level
0.713 0.287 0.000
Y52 Agents primarily affecting the cardiovascular system
0.713 0.287 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.713 0.287 0.000
A49 Bacterial infection of unspecified site
0.712 0.288 0.000
M34 Systemic sclerosis
0.712 0.288 0.000
T92.1 Sequelae of fracture of arm
0.712 0.288 0.000
D51 Vitamin B12 deficiency anaemia
0.712 0.288 0.000
W07.9 Unspecified place
0.711 0.289 0.000
A41 Other septicaemia
0.711 0.289 0.000
J11 Influenza, virus not identified
0.710 0.290 0.000
S32.1 Fracture of sacrum
0.709 0.290 0.000
N99-N99 Other disorders of the genitourinary system
0.709 0.291 0.000
T93.2 Sequelae of other fractures of lower limb
0.707 0.293 0.000
T95 Sequelae of burns, corrosions and frostbite
0.706 0.294 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.706 0.294 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.706 0.294 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.706 0.294 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.706 0.294 0.000
L10-L14 Bullous disorders
0.705 0.295 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.705 0.295 0.000
I00-I02 Acute rheumatic fever
0.705 0.295 0.000
M91-M94 Chondropathies
0.704 0.296 0.000
S90-S99 Injuries to the ankle and foot
0.704 0.296 0.000
N75.0 Cyst of Bartholin's gland
0.703 0.297 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.702 0.298 0.000
L89.2 Stage III decubitus ulcer
0.702 0.298 0.000
L53 Other erythematous conditions
0.701 0.299 0.000
D67 Hereditary factor IX deficiency
0.700 0.300 0.000
D66 Hereditary factor VIII deficiency
0.700 0.300 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.700 0.300 0.000
T87 Complications peculiar to reattachment and amputation
0.700 0.300 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.700 0.300 0.000
Y44 Agents primarily affecting blood constituents
0.700 0.300 0.000
U80 Agent resistant to penicillin and related antibiotics
0.699 0.301 0.000
S52.6 Fracture of lower end of both ulna and radius
0.699 0.301 0.000
M06 Other rheumatoid arthritis
0.698 0.302 0.000
B37.3 Candidiasis of vulva and vagina
0.698 0.302 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.698 0.302 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.698 0.302 0.000
L94 Other localised connective tissue disorders
0.698 0.302 0.000
L87 Transepidermal elimination disorders
0.698 0.302 0.000
L88 Pyoderma gangrenosum
0.698 0.302 0.000
L86 Keratoderma in diseases classified elsewhere
0.698 0.302 0.000
L80 Vitiligo
0.698 0.302 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.698 0.302 0.000
W19.2 School, other institution and public administrative area
0.697 0.303 0.000
S52.8 Fracture of other parts of forearm
0.697 0.303 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.697 0.303 0.000
T68 Hypothermia
0.696 0.304 0.000
I78.1 Naevus, nonneoplastic
0.695 0.305 0.000
I20.9 Angina pectoris, unspecified
0.695 0.305 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.695 0.305 0.000
I67.8 Other specified cerebrovascular diseases
0.694 0.306 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.693 0.307 0.000
I20.1 Angina pectoris with documented spasm
0.693 0.307 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.693 0.307 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.692 0.308 0.000
N17.8 Other acute renal failure
0.691 0.309 0.000
N17.2 Acute renal failure with medullary necrosis
0.691 0.309 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.691 0.309 0.000
N17.0 Acute renal failure with tubular necrosis
0.691 0.309 0.000
A07 Other protozoal intestinal diseases
0.691 0.309 0.000
A06 Amoebiasis
0.691 0.309 0.000
A05 Other bacterial foodborne intoxications
0.691 0.309 0.000
A03 Shigellosis
0.691 0.309 0.000
A02 Other Salmonella infections
0.691 0.309 0.000
A01 Typhoid and paratyphoid fevers
0.691 0.309 0.000
A00 Cholera
0.691 0.309 0.000
Z34 Supervision of normal pregnancy
0.690 0.310 0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb
0.689 0.311 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.689 0.311 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.689 0.311 0.000
Q50-Q56 Congenital malformations of genital organs
0.689 0.311 0.000
Y43 Primarily systemic agents
0.688 0.312 0.000
I78.8 Other diseases of capillaries
0.687 0.313 0.000
M24 Other specific joint derangements
0.687 0.313 0.000
I70 Atherosclerosis
0.686 0.313 0.000
S20-S29 Injuries to the thorax
0.686 0.314 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.686 0.314 0.000
I71.0 Dissection of aorta [any part]
0.685 0.315 0.000
I62 Other nontraumatic intracranial haemorrhage
0.684 0.316 0.000
E10 Insulin-dependent diabetes mellitus
0.684 0.316 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.684 0.316 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.683 0.317 0.000
Q80-Q89 Other congenital malformations
0.683 0.317 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.683 0.317 0.000
Q35-Q37 Cleft lip and cleft palate
0.683 0.317 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.683 0.317 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.683 0.317 0.000
W06 Fall involving bed
0.683 0.317 0.000
D69.9 Haemorrhagic condition, unspecified
0.683 0.317 0.000
D69.8 Other specified haemorrhagic conditions
0.683 0.317 0.000
D69.4 Other primary thrombocytopenia
0.683 0.317 0.000
D69.2 Other nonthrombocytopenic purpura
0.683 0.317 0.000
D69.1 Qualitative platelet defects
0.683 0.317 0.000
D69.0 Allergic purpura
0.683 0.317 0.000
S48 Traumatic amputation of shoulder and upper arm
0.683 0.317 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.683 0.317 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.683 0.317 0.000
S44 Injury of nerves at shoulder and upper arm level
0.683 0.317 0.000
S41 Open wound of shoulder and upper arm
0.683 0.317 0.000
S47 Crushing injury of shoulder and upper arm
0.683 0.317 0.000
T92.9 Sequelae of unspecified injury of upper limb
0.682 0.318 0.000
E65-E68 Obesity and other hyperalimentation
0.681 0.319 0.000
J17 Pneumonia in diseases classified elsewhere
0.681 0.319 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.681 0.319 0.000
J12 Viral pneumonia, not elsewhere classified
0.681 0.319 0.000
J10 Influenza due to identified influenza virus
0.681 0.319 0.000
J14 Pneumonia due to Haemophilus influenzae
0.681 0.319 0.000
J09 Influenza due to certain identified influenza virus
0.681 0.319 0.000
M25 Other joint disorders, not elsewhere classified
0.680 0.320 0.000
D68.0 Von Willebrand's disease
0.680 0.320 0.000
S59 Other and unspecified injuries of forearm
0.679 0.321 0.000
S58 Traumatic amputation of forearm
0.679 0.321 0.000
S57 Crushing injury of forearm
0.679 0.321 0.000
S55 Injury of blood vessels at forearm level
0.679 0.321 0.000
S54 Injury of nerves at forearm level
0.679 0.321 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.679 0.321 0.000
I24.8 Other forms of acute ischaemic heart disease
0.679 0.321 0.000
B35 Dermatophytosis
0.679 0.321 0.000
L51 Erythema multiforme
0.678 0.322 0.000
T85.2 Mechanical complication of intraocular lens
0.678 0.322 0.000
E11.5 With peripheral circulatory complications
0.677 0.323 0.000
Q63 Other congenital malformations of kidney
0.677 0.323 0.000
Z33 Pregnant state, incidental
0.676 0.324 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.676 0.324 0.000
Z39 Postpartum care and examination
0.675 0.325 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.675 0.325 0.000
M21.0 Valgus deformity, not elsewhere classified
0.675 0.325 0.000
W17 Other fall from one level to another
0.674 0.326 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.674 0.326 0.000
W15 Fall from cliff
0.674 0.326 0.000
W14 Fall from tree
0.674 0.326 0.000
W12 Fall on and from scaffolding
0.674 0.326 0.000
W11 Fall on and from ladder
0.674 0.326 0.000
W09 Fall involving playground equipment
0.674 0.326 0.000
W08 Fall involving other furniture
0.674 0.326 0.000
W05 Fall involving wheelchair
0.674 0.326 0.000
W04 Fall while being carried or supported by other persons
0.674 0.326 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.674 0.326 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.674 0.326 0.000
W00 Fall on same level involving ice and snow
0.674 0.326 0.000
J18.8 Other pneumonia, organism unspecified
0.672 0.328 0.000
J18.2 Hypostatic pneumonia, unspecified
0.672 0.328 0.000
S06 Intracranial injury
0.672 0.328 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.672 0.328 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.672 0.328 0.000
E29 Testicular dysfunction
0.671 0.329 0.000
J60-J70 Lung diseases due to external agents
0.671 0.329 0.000
E22 Hyperfunction of pituitary gland
0.671 0.329 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.670 0.329 0.000
M22 Disorders of patella
0.670 0.330 0.000
S69 Other and unspecified injuries of wrist and hand
0.670 0.330 0.000
N75.1 Abscess of Bartholin's gland
0.669 0.331 0.000
S70 Superficial injury of hip and thigh
0.669 0.331 0.000
J41 Simple and mucopurulent chronic bronchitis
0.668 0.332 0.000
S50.9 Superficial injury of forearm, unspecified
0.668 0.332 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.668 0.332 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.668 0.332 0.000
S42.3 Fracture of shaft of humerus
0.667 0.333 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.667 0.333 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.667 0.333 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.667 0.333 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.667 0.333 0.000
Z12 Special screening examination for neoplasms
0.666 0.333 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.666 0.334 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.665 0.335 0.000
E27.8 Other specified disorders of adrenal gland
0.664 0.335 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.663 0.337 0.000
E26 Hyperaldosteronism
0.662 0.338 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.662 0.338 0.000
D80-D89 Certain disorders involving the immune mechanism
0.661 0.339 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.661 0.339 0.000
S37 Injury of urinary and pelvic organs
0.661 0.339 0.000
S36 Injury of intra-abdominal organs
0.661 0.339 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.661 0.339 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.661 0.339 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.661 0.339 0.000
S31 Open wound of abdomen, lower back and pelvis
0.661 0.339 0.000
N71 Inflammatory disease of uterus, except cervix
0.660 0.340 0.000
Y57.9 Drug or medicament, unspecified
0.659 0.341 0.000
I23 Certain current complications following acute myocardial infarction
0.659 0.341 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.658 0.342 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.658 0.342 0.000
Q61.2 Polycystic kidney, adult type
0.658 0.342 0.000
Y59 Other and unspecified vaccines and biological substances
0.658 0.342 0.000
Y58 Bacterial vaccines
0.658 0.342 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.658 0.342 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.658 0.342 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.658 0.342 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.658 0.342 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.658 0.342 0.000
Y48 Anaesthetics and therapeutic gases
0.658 0.342 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.658 0.342 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.658 0.342 0.000
S02.6 Fracture of mandible
0.657 0.343 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.656 0.344 0.000
M80-M85 Disorders of bone density and structure
0.656 0.344 0.000
N18.0 End-stage renal disease
0.656 0.344 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.656 0.344 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.656 0.344 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.655 0.345 0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb
0.655 0.345 0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb
0.655 0.345 0.000
T93.4 Sequelae of injury of nerve of lower limb
0.655 0.345 0.000
T93.1 Sequelae of fracture of femur
0.655 0.345 0.000
M60-M63 Disorders of muscles
0.655 0.345 0.000
S19 Other and unspecified injuries of neck
0.655 0.345 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.654 0.346 0.000
M00-M03 Infectious arthropathies
0.653 0.347 0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level
0.651 0.349 0.000
S60 Superficial injury of wrist and hand
0.651 0.349 0.000
N76.8 Other specified inflammation of vagina and vulva
0.651 0.349 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.650 0.350 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.649 0.351 0.000
J45.0 Predominantly allergic asthma
0.649 0.351 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.648 0.352 0.000
E23 Hypofunction and other disorders of pituitary gland
0.648 0.352 0.000
Z02 Examination and encounter for administrative purposes
0.648 0.352 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.648 0.352 0.000
S10 Superficial injury of neck
0.647 0.353 0.000
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.647 0.353 0.000
L58 Radiodermatitis
0.647 0.353 0.000
L56 Other acute skin changes due to ultraviolet radiation
0.647 0.353 0.000
L55 Sunburn
0.647 0.353 0.000
B48 Other mycoses, not elsewhere classified
0.647 0.353 0.000
B47 Mycetoma
0.647 0.353 0.000
B46 Zygomycosis
0.647 0.353 0.000
B45 Cryptococcosis
0.647 0.353 0.000
B44 Aspergillosis
0.647 0.353 0.000
B43 Chromomycosis and phaeomycotic abscess
0.647 0.353 0.000
B42 Sporotrichosis
0.647 0.353 0.000
B41 Paracoccidioidomycosis
0.647 0.353 0.000
B40 Blastomycosis
0.647 0.353 0.000
B39 Histoplasmosis
0.647 0.353 0.000
B38 Coccidioidomycosis
0.647 0.353 0.000
B36 Other superficial mycoses
0.647 0.353 0.000
B49 Unspecified mycosis
0.647 0.353 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.647 0.353 0.000
E40-E46 Malnutrition
0.646 0.354 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.646 0.354 0.000
I74.5 Embolism and thrombosis of iliac artery
0.646 0.354 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.645 0.355 0.000
N18.8 Other chronic renal failure
0.645 0.355 0.000
N18.2 Chronic kidney disease, stage 2
0.645 0.355 0.000
N18.1 Chronic kidney disease, stage 1
0.645 0.355 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.643 0.357 0.000
A46 Erysipelas
0.643 0.357 0.000
L81 Other disorders of pigmentation
0.643 0.357 0.000
T86 Failure and rejection of transplanted organs and tissues
0.642 0.358 0.000
S12 Fracture of neck
0.641 0.359 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.641 0.359 0.000
S71 Open wound of hip and thigh
0.641 0.359 0.000
M13 Other arthritis
0.641 0.359 0.000
S56.4 Injury of extensor muscle and tendon of other finger(s) at forearm level
0.641 0.359 0.000
I21 Acute myocardial infarction
0.641 0.359 0.000
G90-G99 Other disorders of the nervous system
0.641 0.359 0.000
S42.4 Fracture of lower end of humerus
0.641 0.359 0.000
O80-O84 Delivery
0.640 0.360 0.000
D52 Folate deficiency anaemia
0.640 0.360 0.000
L89.3 Stage IV decubitus ulcer
0.640 0.360 0.000
I67.1 Cerebral aneurysm, nonruptured
0.640 0.360 0.000
I05-I09 Chronic rheumatic heart diseases
0.639 0.361 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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