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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs76888481
log Bayes Factor = 17.9427
Chromosome 18   position 67,521,736  (GRCh37) Explore rs76888481 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.999 0.001 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.999 0.001 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.997 0.003 0.000
I51 Complications and ill-defined descriptions of heart disease
0.997 0.003 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.996 0.004 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.994 0.006 0.000
Chapter XX External causes of morbidity and mortality
0.993 0.007 0.000
I25.2 Old myocardial infarction
0.993 0.007 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.993 0.007 0.000
D50-D53 Nutritional anaemias
0.991 0.009 0.000
I51.8 Other ill-defined heart diseases
0.987 0.013 0.000
I50 Heart failure
0.984 0.016 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.977 0.023 0.000
G40-G47 Episodic and paroxysmal disorders
0.976 0.024 0.000
Z95.0 Presence of cardiac pacemaker
0.973 0.027 0.000
D51 Vitamin B12 deficiency anaemia
0.969 0.031 0.000
D50 Iron deficiency anaemia
0.965 0.035 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.965 0.035 0.000
G90-G99 Other disorders of the nervous system
0.964 0.036 0.000
Z45 Adjustment and management of implanted device
0.963 0.037 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.961 0.039 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.959 0.041 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.954 0.046 0.000
D50.8 Other iron deficiency anaemias
0.952 0.048 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.949 0.051 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.941 0.059 0.000
Chapter VIII Diseases of the ear and mastoid process
0.941 0.059 0.000
Z41 Procedures for purposes other than remedying health state
0.940 0.060 0.000
G47 Sleep disorders
0.938 0.062 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.936 0.064 0.000
I24 Other acute ischaemic heart diseases
0.936 0.064 0.000
I44 Atrioventricular and left bundle-branch block
0.935 0.065 0.000
Z93 Artificial opening status
0.935 0.065 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.931 0.069 0.000
Chapter X Diseases of the respiratory system
0.929 0.071 0.000
I73 Other peripheral vascular diseases
0.925 0.075 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.925 0.075 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.924 0.076 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.921 0.079 0.000
I73.9 Peripheral vascular disease, unspecified
0.914 0.086 0.000
G95 Other diseases of spinal cord
0.912 0.088 0.000
I50.0 Congestive heart failure
0.911 0.089 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.907 0.093 0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance
0.903 0.097 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.900 0.100 0.000
Chapter I Certain infectious and parasitic diseases
0.899 0.101 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.899 0.101 0.000
H65-H75 Diseases of middle ear and mastoid
0.897 0.103 0.000
I35 Nonrheumatic aortic valve disorders
0.895 0.105 0.000
I47 Paroxysmal tachycardia
0.892 0.108 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.891 0.109 0.000
Z43 Attention to artificial openings
0.887 0.113 0.000
I50.9 Heart failure, unspecified
0.885 0.115 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.885 0.115 0.000
I51.7 Cardiomegaly
0.885 0.115 0.000
Z95.4 Presence of other heart-valve replacement
0.882 0.118 0.000
I25.5 Ischaemic cardiomyopathy
0.872 0.128 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.871 0.129 0.000
I44.7 Left bundle-branch block, unspecified
0.871 0.129 0.000
Z98 Other postsurgical states
0.867 0.133 0.000
I50.1 Left ventricular failure
0.863 0.137 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.862 0.138 0.000
W00-W19 Falls
0.861 0.139 0.000
I74 Arterial embolism and thrombosis
0.859 0.141 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.855 0.145 0.000
G43 Migraine
0.855 0.145 0.000
Z93.6 Other artificial openings of urinary tract status
0.855 0.145 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.854 0.146 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.853 0.147 0.000
Z40 Prophylactic surgery
0.851 0.149 0.000
G47.3 Sleep apnoea
0.850 0.150 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.848 0.152 0.000
G20-G26 Extrapyramidal and movement disorders
0.842 0.158 0.000
B25-B34 Other viral diseases
0.839 0.161 0.000
I22 Subsequent myocardial infarction
0.838 0.162 0.000
S40-S49 Injuries to the shoulder and upper arm
0.836 0.164 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.836 0.164 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.835 0.165 0.000
Chapter VII Diseases of the eye and adnexa
0.834 0.166 0.000
G95.2 Cord compression, unspecified
0.834 0.166 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.828 0.172 0.000
I24.8 Other forms of acute ischaemic heart disease
0.826 0.174 0.000
I26 Pulmonary embolism
0.826 0.174 0.000
Chapter XXII Codes for special purposes
0.825 0.175 0.000
Y40 Systemic antibiotics
0.824 0.176 0.000
I49 Other cardiac arrhythmias
0.824 0.176 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.824 0.176 0.000
Z95.2 Presence of prosthetic heart valve
0.824 0.176 0.000
H71 Cholesteatoma of middle ear
0.822 0.178 0.000
Z95.1 Presence of aortocoronary bypass graft
0.821 0.179 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.820 0.180 0.000
R21 Rash and other nonspecific skin eruption
0.819 0.181 0.000
I25.1 Atherosclerotic heart disease
0.819 0.181 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.816 0.184 0.000
Z52 Donors of organs and tissues
0.815 0.185 0.000
Z47 Other orthopaedic follow-up care
0.813 0.187 0.000
Y52 Agents primarily affecting the cardiovascular system
0.813 0.187 0.000
I33 Acute and subacute endocarditis
0.810 0.189 0.000
H66 Suppurative and unspecified otitis media
0.810 0.190 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.808 0.192 0.000
I27 Other pulmonary heart diseases
0.807 0.193 0.000
J84 Other interstitial pulmonary diseases
0.805 0.195 0.000
B95-B98 Bacterial, viral and other infectious agents
0.805 0.195 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.805 0.195 0.000
Z95.3 Presence of xenogenic heart valve
0.803 0.197 0.000
I51.9 Heart disease, unspecified
0.803 0.197 0.000
T82.1 Mechanical complication of cardiac electronic device
0.803 0.197 0.000
S20-S29 Injuries to the thorax
0.800 0.200 0.000
I38 Endocarditis, valve unspecified
0.799 0.201 0.000
Z43.6 Attention to other artificial openings of urinary tract
0.799 0.201 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.798 0.202 0.000
G51 Facial nerve disorders
0.798 0.202 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.797 0.203 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.796 0.204 0.000
B34 Viral infection of unspecified site
0.796 0.204 0.000
T93 Sequelae of injuries of lower limb
0.794 0.206 0.000
J95-J99 Other diseases of the respiratory system
0.793 0.207 0.000
I35.0 Aortic (valve) stenosis
0.791 0.209 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.789 0.211 0.000
Z98.8 Other specified postsurgical states
0.788 0.212 0.000
I34 Nonrheumatic mitral valve disorders
0.788 0.212 0.000
G90 Disorders of autonomic nervous system
0.787 0.213 0.000
I47.2 Ventricular tachycardia
0.786 0.214 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.785 0.215 0.000
G95.9 Disease of spinal cord, unspecified
0.785 0.215 0.000
Z50 Care involving use of rehabilitation procedures
0.785 0.215 0.000
Y57 Other and unspecified drugs and medicaments
0.784 0.216 0.000
Y83.5 Amputation of limb(s)
0.784 0.216 0.000
G44 Other headache syndromes
0.780 0.220 0.000
G43.9 Migraine, unspecified
0.777 0.223 0.000
I31 Other diseases of pericardium
0.776 0.224 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.775 0.225 0.000
D80-D89 Certain disorders involving the immune mechanism
0.773 0.227 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.772 0.228 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.772 0.228 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.771 0.229 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.770 0.230 0.000
G56 Mononeuropathies of upper limb
0.769 0.231 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.769 0.231 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.768 0.232 0.000
Z91.6 Personal history of other physical trauma
0.768 0.232 0.000
G30-G32 Other degenerative diseases of the nervous system
0.767 0.233 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.764 0.236 0.000
H74 Other disorders of middle ear and mastoid
0.764 0.236 0.000
Y83.3 Surgical operation with formation of external stoma
0.762 0.238 0.000
T66-T78 Other and unspecified effects of external causes
0.761 0.239 0.000
J60-J70 Lung diseases due to external agents
0.760 0.240 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.757 0.243 0.000
I37 Pulmonary valve disorders
0.757 0.243 0.000
Z93.2 Ileostomy status
0.755 0.245 0.000
B34.9 Viral infection, unspecified
0.754 0.246 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.754 0.246 0.000
Z89 Acquired absence of limb
0.751 0.249 0.000
X60-X84 Intentional self-harm
0.751 0.249 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.751 0.249 0.000
I44.3 Other and unspecified atrioventricular block
0.750 0.250 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.749 0.251 0.000
G96 Other disorders of central nervous system
0.748 0.252 0.000
I45 Other conduction disorders
0.748 0.252 0.000
Z45.2 Adjustment and management of vascular access device
0.747 0.253 0.000
V20-V29 Motorcycle rider injured in transport accident
0.746 0.254 0.000
H90-H95 Other disorders of ear
0.744 0.255 0.000
I25.3 Aneurysm of heart
0.743 0.257 0.000
Z93.1 Gastrostomy status
0.743 0.257 0.000
I70 Atherosclerosis
0.741 0.259 0.000
T82.3 Mechanical complication of other vascular grafts
0.740 0.259 0.000
I74.5 Embolism and thrombosis of iliac artery
0.740 0.260 0.000
Z93.0 Tracheostomy status
0.739 0.261 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.738 0.262 0.000
Z45.8 Adjustment and management of other implanted devices
0.737 0.263 0.000
J40-J47 Chronic lower respiratory diseases
0.736 0.264 0.000
Z45.1 Adjustment and management of infusion pump
0.735 0.265 0.000
H43-H45 Disorders of vitreous body and globe
0.733 0.267 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.731 0.269 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.730 0.270 0.000
Z48 Other surgical follow-up care
0.729 0.271 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.729 0.271 0.000
S90-S99 Injuries to the ankle and foot
0.729 0.271 0.000
D50.9 Iron deficiency anaemia, unspecified
0.728 0.272 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.728 0.272 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.728 0.272 0.000
S10-S19 Injuries to the neck
0.727 0.273 0.000
S50-S59 Injuries to the elbow and forearm
0.726 0.274 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.725 0.275 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.724 0.276 0.000
G40 Epilepsy
0.724 0.276 0.000
G35 Multiple sclerosis
0.722 0.278 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.722 0.278 0.000
S70-S79 Injuries to the hip and thigh
0.720 0.280 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.717 0.283 0.000
G93 Other disorders of brain
0.717 0.283 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.717 0.283 0.000
T86 Failure and rejection of transplanted organs and tissues
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I30 Acute pericarditis
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
I46 Cardiac arrest
0.717 0.283 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.717 0.283 0.000
G70-G73 Diseases of myoneural junction and muscle
0.716 0.284 0.000
Z91.8 Personal history of other specified risk-factors, not elsewhere classified
0.716 0.284 0.000
Z91.7 Personal history of female genital mutilation
0.716 0.284 0.000
Z91.4 Personal history of psychological trauma, not elsewhere classified
0.716 0.284 0.000
Z91.3 Personal history of unhealthy sleep-wake schedule
0.716 0.284 0.000
Z91.2 Personal history of poor personal hygiene
0.716 0.284 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.716 0.284 0.000
I51.6 Cardiovascular disease, unspecified
0.714 0.285 0.000
I51.5 Myocardial degeneration
0.714 0.285 0.000
I51.4 Myocarditis, unspecified
0.714 0.285 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.714 0.285 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.714 0.285 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.714 0.285 0.000
I51.0 Cardiac septal defect, acquired
0.714 0.285 0.000
T33-T35 Frostbite
0.714 0.286 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.714 0.286 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.714 0.286 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.714 0.286 0.000
T00-T07 Injuries involving multiple body regions
0.714 0.286 0.000
Z43.4 Attention to other artificial openings of digestive tract
0.714 0.286 0.000
H60-H62 Diseases of external ear
0.713 0.287 0.000
D55-D59 Haemolytic anaemias
0.713 0.287 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.713 0.287 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.712 0.288 0.000
Y35-Y36 Legal intervention and operations of war
0.712 0.288 0.000
Y10-Y34 Event of undetermined intent
0.712 0.288 0.000
Y00-Y09 Assault
0.712 0.288 0.000
X85-X99 Assault
0.712 0.288 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.712 0.288 0.000
X50-X57 Overexertion, travel and privation
0.712 0.288 0.000
X30-X39 Exposure to forces of nature
0.712 0.288 0.000
X20-X29 Contact with venomous animals and plants
0.712 0.288 0.000
X10-X19 Contact with heat and hot substances
0.712 0.288 0.000
X00-X09 Exposure to smoke, fire and flames
0.712 0.288 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.712 0.288 0.000
W75-W84 Other accidental threats to breathing
0.712 0.288 0.000
W65-W74 Accidental drowning and submersion
0.712 0.288 0.000
W50-W64 Exposure to animate mechanical forces
0.712 0.288 0.000
V98-V99 Other and unspecified transport accidents
0.712 0.288 0.000
V95-V97 Air and space transport accidents
0.712 0.288 0.000
V90-V94 Water transport accidents
0.712 0.288 0.000
V70-V79 Bus occupant injured in transport accident
0.712 0.288 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.712 0.288 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.712 0.288 0.000
V40-V49 Car occupant injured in transport accident
0.712 0.288 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.712 0.288 0.000
V01-V09 Pedestrian injured in transport accident
0.712 0.288 0.000
Z54 Convalescence
0.712 0.288 0.000
Z44 Fitting and adjustment of external prosthetic device
0.712 0.288 0.000
T93.2 Sequelae of other fractures of lower limb
0.711 0.289 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.711 0.289 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.711 0.289 0.000
D53 Other nutritional anaemias
0.710 0.289 0.000
S80-S89 Injuries to the knee and lower leg
0.710 0.290 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.710 0.290 0.000
G59.0 Diabetic mononeuropathy
0.710 0.290 0.000
A80-A89 Viral infections of the central nervous system
0.709 0.291 0.000
V80-V89 Other land transport accidents
0.706 0.294 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.706 0.294 0.000
D60-D64 Aplastic and other anaemias
0.705 0.295 0.000
I42 Cardiomyopathy
0.705 0.295 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.704 0.296 0.000
G25 Other extrapyramidal and movement disorders
0.703 0.297 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.702 0.298 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.701 0.299 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.701 0.299 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.701 0.299 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.701 0.299 0.000
Z82.2 Family history of deafness and hearing loss
0.701 0.299 0.000
Z82.1 Family history of blindness and visual loss
0.701 0.299 0.000
G47.9 Sleep disorder, unspecified
0.701 0.299 0.000
T90 Sequelae of injuries of head
0.701 0.299 0.000
J30-J39 Other diseases of upper respiratory tract
0.701 0.299 0.000
I72 Other aneurysm
0.700 0.300 0.000
G24 Dystonia
0.700 0.300 0.000
I35.1 Aortic (valve) insufficiency
0.700 0.300 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.700 0.300 0.000
G41 Status epilepticus
0.700 0.300 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.698 0.302 0.000
I21 Acute myocardial infarction
0.698 0.302 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.698 0.302 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.697 0.303 0.000
Y83.8 Other surgical procedures
0.696 0.304 0.000
D51.8 Other vitamin B12 deficiency anaemias
0.695 0.305 0.000
D51.3 Other dietary vitamin B12 deficiency anaemia
0.695 0.305 0.000
D51.2 Transcobalamin II deficiency
0.695 0.305 0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.695 0.305 0.000
Y40.9 Systemic antibiotic, unspecified
0.694 0.306 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.694 0.306 0.000
T51 Toxic effect of alcohol
0.693 0.307 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.692 0.308 0.000
D50.1 Sideropenic dysphagia
0.692 0.308 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.692 0.308 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.691 0.309 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.691 0.309 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.691 0.309 0.000
G92 Toxic encephalopathy
0.691 0.309 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.691 0.309 0.000
R30-R39 Symptoms and signs involving the urinary system
0.691 0.309 0.000
Z45.9 Adjustment and management of unspecified implanted device
0.690 0.309 0.000
Z45.3 Adjustment and management of implanted hearing device
0.690 0.309 0.000
H66.3 Other chronic suppurative otitis media
0.690 0.310 0.000
H66.9 Otitis media, unspecified
0.690 0.310 0.000
T87 Complications peculiar to reattachment and amputation
0.688 0.312 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.688 0.312 0.000
Z52.4 Kidney donor
0.687 0.313 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.685 0.315 0.000
Z93.5 Cystostomy status
0.684 0.316 0.000
Y59 Other and unspecified vaccines and biological substances
0.684 0.316 0.000
Y58 Bacterial vaccines
0.684 0.316 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.684 0.316 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.684 0.316 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.684 0.316 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.684 0.316 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.684 0.316 0.000
Y48 Anaesthetics and therapeutic gases
0.684 0.316 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.684 0.316 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.684 0.316 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.684 0.316 0.000
V10-V19 Pedal cyclist injured in transport accident
0.683 0.317 0.000
Z82.3 Family history of stroke
0.683 0.317 0.000
Y84.6 Urinary catheterisation
0.682 0.318 0.000
I44.2 Atrioventricular block, complete
0.682 0.318 0.000
Z98.1 Arthrodesis status
0.680 0.320 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.679 0.321 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.678 0.322 0.000
I31.9 Disease of pericardium, unspecified
0.677 0.322 0.000
I49.9 Cardiac arrhythmia, unspecified
0.676 0.324 0.000
Y83.6 Removal of other organ (partial) (total)
0.676 0.324 0.000
I33.0 Acute and subacute infective endocarditis
0.675 0.325 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.674 0.326 0.000
Z41.9 Procedures for purposes other than remedying health state, unspecified
0.674 0.326 0.000
Z41.8 Other procedures for purposes other than remedying health state
0.674 0.326 0.000
Z41.3 Ear piercing
0.674 0.326 0.000
Z41.2 Routine and ritual circumcision
0.674 0.326 0.000
Z41.0 Hair transplant
0.674 0.326 0.000
Z91.5 Personal history of self-harm
0.674 0.326 0.000
I44.1 Atrioventricular block, second degree
0.673 0.327 0.000
W18 Other fall on same level
0.673 0.327 0.000
I27.0 Primary pulmonary hypertension
0.673 0.327 0.000
G47.8 Other sleep disorders
0.673 0.327 0.000
G47.4 Narcolepsy and cataplexy
0.673 0.327 0.000
G47.2 Disorders of the sleep-wake schedule
0.673 0.327 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.672 0.328 0.000
S30.0 Contusion of lower back and pelvis
0.671 0.329 0.000
I24.1 Dressler's syndrome
0.671 0.329 0.000
G82 Paraplegia and tetraplegia
0.671 0.329 0.000
I44.6 Other and unspecified fascicular block
0.671 0.329 0.000
I44.5 Left posterior fascicular block
0.671 0.329 0.000
I44.4 Left anterior fascicular block
0.671 0.329 0.000
G56.0 Carpal tunnel syndrome
0.670 0.330 0.000
Z93.9 Artificial opening status, unspecified
0.670 0.330 0.000
Z93.8 Other artificial opening status
0.670 0.330 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.670 0.330 0.000
I49.5 Sick sinus syndrome
0.669 0.331 0.000
G56.8 Other mononeuropathies of upper limb
0.668 0.332 0.000
I28 Other diseases of pulmonary vessels
0.667 0.332 0.000
D52 Folate deficiency anaemia
0.667 0.333 0.000
W13 Fall from, out of or through building or structure
0.667 0.333 0.000
Z42 Follow-up care involving plastic surgery
0.666 0.334 0.000
T79-T79 Certain early complications of trauma
0.666 0.334 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.666 0.334 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.665 0.335 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.665 0.335 0.000
Q50-Q56 Congenital malformations of genital organs
0.665 0.335 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.664 0.335 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.664 0.336 0.000
I73.8 Other specified peripheral vascular diseases
0.663 0.336 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.663 0.336 0.000
W19 Unspecified fall
0.663 0.337 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.663 0.337 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.663 0.337 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.663 0.337 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.663 0.337 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.663 0.337 0.000
T68 Hypothermia
0.662 0.338 0.000
G58 Other mononeuropathies
0.660 0.340 0.000
G54 Nerve root and plexus disorders
0.660 0.340 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.660 0.340 0.000
G52 Disorders of other cranial nerves
0.660 0.340 0.000
G90.2 Horner's syndrome
0.659 0.340 0.000
S20 Superficial injury of thorax
0.659 0.341 0.000
G95.8 Other specified diseases of spinal cord
0.659 0.341 0.000
G51.9 Disorder of facial nerve, unspecified
0.659 0.341 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.658 0.342 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.657 0.343 0.000
S60-S69 Injuries to the wrist and hand
0.657 0.343 0.000
Z50.5 Speech therapy
0.656 0.343 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.655 0.345 0.000
G51.0 Bell's palsy
0.655 0.345 0.000
G95.1 Vascular myelopathies
0.654 0.346 0.000
G95.0 Syringomyelia and syringobulbia
0.654 0.346 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.654 0.346 0.000
W06 Fall involving bed
0.653 0.347 0.000
Y44 Agents primarily affecting blood constituents
0.652 0.347 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.652 0.348 0.000
G50 Disorders of trigeminal nerve
0.652 0.348 0.000
G44.0 Cluster headache syndrome
0.652 0.348 0.000
R06 Abnormalities of breathing
0.652 0.348 0.000
Z43.1 Attention to gastrostomy
0.651 0.349 0.000
S40 Superficial injury of shoulder and upper arm
0.650 0.350 0.000
I44.0 Atrioventricular block, first degree
0.650 0.350 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.650 0.350 0.000
J09-J18 Influenza and pneumonia
0.649 0.351 0.000
S30.1 Contusion of abdominal wall
0.649 0.351 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.647 0.353 0.000
H53-H54 Visual disturbances and blindness
0.646 0.354 0.000
S27 Injury of other and unspecified intrathoracic organs
0.646 0.354 0.000
I34.0 Mitral (valve) insufficiency
0.645 0.355 0.000
B15-B19 Viral hepatitis
0.645 0.355 0.000
B99-B99 Other infectious diseases
0.644 0.356 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.644 0.356 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.644 0.356 0.000
B65-B83 Helminthiases
0.644 0.356 0.000
B50-B64 Protozoal diseases
0.644 0.356 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.644 0.356 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.644 0.356 0.000
A75-A79 Rickettsioses
0.644 0.356 0.000
A70-A74 Other diseases caused by chlamydiae
0.644 0.356 0.000
A65-A69 Other spirochaetal diseases
0.644 0.356 0.000
A20-A28 Certain zoonotic bacterial diseases
0.644 0.356 0.000
A15-A19 Tuberculosis
0.644 0.356 0.000
W07 Fall involving chair
0.644 0.356 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.643 0.357 0.000
H70 Mastoiditis and related conditions
0.643 0.357 0.000
H69 Other disorders of Eustachian tube
0.643 0.357 0.000
H68 Eustachian salpingitis and obstruction
0.643 0.357 0.000
H67 Otitis media in diseases classified elsewhere
0.643 0.357 0.000
I35.9 Aortic valve disorder, unspecified
0.642 0.358 0.000
I35.8 Other aortic valve disorders
0.642 0.358 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.642 0.358 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.641 0.358 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.641 0.359 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.641 0.359 0.000
S43.0 Dislocation of shoulder joint
0.640 0.359 0.000
I47.0 Reentry ventricular arrhythmia
0.640 0.360 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.640 0.360 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.639 0.361 0.000
D86 Sarcoidosis
0.638 0.362 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.638 0.362 0.000
Y40.0 Penicillins
0.637 0.363 0.000
R35 Polyuria
0.637 0.363 0.000
Z43.9 Attention to unspecified artificial opening
0.636 0.364 0.000
Z43.8 Attention to other artificial openings
0.636 0.364 0.000
Z43.7 Attention to artificial vagina
0.636 0.364 0.000
Z43.5 Attention to cyctostomy
0.636 0.364 0.000
Z43.0 Attention to tracheostomy
0.636 0.364 0.000
H43 Disorders of vitreous body
0.636 0.364 0.000
Z43.3 Attention to colostomy
0.636 0.364 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.636 0.364 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.635 0.365 0.000
T98 Sequelae of other and unspecified effects of external causes
0.634 0.365 0.000
T95 Sequelae of burns, corrosions and frostbite
0.634 0.365 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.634 0.365 0.000
T91 Sequelae of injuries of neck and trunk
0.634 0.365 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.634 0.365 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.634 0.365 0.000
D64 Other anaemias
0.632 0.367 0.000
B34.8 Other viral infections of unspecified site
0.632 0.368 0.000
Z83 Family history of other specific disorders
0.632 0.368 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.631 0.369 0.000
H91 Other hearing loss
0.631 0.369 0.000
I78 Diseases of capillaries
0.628 0.371 0.000
R04 Haemorrhage from respiratory passages
0.628 0.372 0.000
Q60-Q64 Congenital malformations of the urinary system
0.627 0.372 0.000
I47.1 Supraventricular tachycardia
0.627 0.373 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.627 0.373 0.000
H10-H13 Disorders of conjunctiva
0.627 0.373 0.000
J44 Other chronic obstructive pulmonary disease
0.627 0.373 0.000
H30-H36 Disorders of choroid and retina
0.626 0.374 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.624 0.375 0.000
S37 Injury of urinary and pelvic organs
0.624 0.375 0.000
S36 Injury of intra-abdominal organs
0.624 0.375 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.624 0.375 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.624 0.375 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.624 0.375 0.000
S31 Open wound of abdomen, lower back and pelvis
0.624 0.375 0.000
Chapter V Mental and behavioural disorders
0.624 0.376 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.623 0.376 0.000
I05-I09 Chronic rheumatic heart diseases
0.623 0.377 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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