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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs76959518
log Bayes Factor = 25.0916
Chromosome 1   position 159,853,160  (GRCh37) Explore rs76959518 on Ensembl!
Variant rs76959518 is part of Cluster X0124

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Z40-Z54 Persons encountering health services for specific procedures and health care
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Z50 Care involving use of rehabilitation procedures
1.000 0.000 0.000
C15-C26 Malignant neoplasms of digestive organs
1.000 0.000 0.000
C18 Malignant neoplasm of colon
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
Z51 Other medical care
0.999 0.001 0.000
Chapter II Neoplasms
0.999 0.001 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.998 0.002 0.000
Z51.0 Radiotherapy session
0.998 0.002 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.998 0.002 0.000
Chapter X Diseases of the respiratory system
0.998 0.002 0.000
I20-I25 Ischaemic heart diseases
0.997 0.003 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.996 0.004 0.000
I30-I52 Other forms of heart disease
0.993 0.007 0.000
R47-R49 Symptoms and signs involving speech and voice
0.993 0.007 0.000
C18.7 Sigmoid colon
0.991 0.009 0.000
I71 Aortic aneurysm and dissection
0.989 0.011 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.988 0.012 0.000
Z50.1 Other physical therapy
0.987 0.013 0.000
Chapter XX External causes of morbidity and mortality
0.986 0.014 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.985 0.015 0.000
J90-J94 Other diseases of pleura
0.984 0.016 0.000
R50-R69 General symptoms and signs
0.981 0.019 0.000
Z43 Attention to artificial openings
0.980 0.020 0.000
Z99.8 Dependence on other enabling machines and devices
0.978 0.022 0.000
I20 Angina pectoris
0.978 0.022 0.000
S00-S09 Injuries to the head
0.977 0.023 0.000
Z45 Adjustment and management of implanted device
0.976 0.024 0.000
J95-J99 Other diseases of the respiratory system
0.975 0.025 0.000
Z96 Presence of other functional implants
0.974 0.026 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.970 0.030 0.000
R47 Speech disturbances, not elsewhere classified
0.969 0.031 0.000
Z96.6 Presence of orthopaedic joint implants
0.969 0.031 0.000
I25 Chronic ischaemic heart disease
0.967 0.033 0.000
I20.0 Unstable angina
0.965 0.035 0.000
I51 Complications and ill-defined descriptions of heart disease
0.965 0.035 0.000
C18.9 Colon, unspecified
0.965 0.035 0.000
Z45.2 Adjustment and management of vascular access device
0.959 0.041 0.000
Z95.1 Presence of aortocoronary bypass graft
0.954 0.046 0.000
Z92 Personal history of medical treatment
0.951 0.049 0.000
J98 Other respiratory disorders
0.950 0.050 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.948 0.052 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.948 0.052 0.000
J92 Pleural plaque
0.946 0.054 0.000
R63 Symptoms and signs concerning food and fluid intake
0.945 0.055 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.944 0.056 0.000
R49 Voice disturbances
0.942 0.058 0.000
R56 Convulsions, not elsewhere classified
0.939 0.061 0.000
Z98 Other postsurgical states
0.939 0.061 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.939 0.061 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.938 0.062 0.000
M80-M85 Disorders of bone density and structure
0.937 0.063 0.000
Z43.2 Attention to ileostomy
0.936 0.064 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.936 0.064 0.000
M50-M54 Other dorsopathies
0.934 0.066 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.933 0.067 0.000
R60 Oedema, not elsewhere classified
0.932 0.068 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.932 0.068 0.000
S70-S79 Injuries to the hip and thigh
0.929 0.071 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.929 0.071 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.927 0.073 0.000
R63.0 Anorexia
0.918 0.082 0.000
I42 Cardiomyopathy
0.912 0.088 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.911 0.089 0.000
R56.8 Other and unspecified convulsions
0.909 0.091 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.909 0.091 0.000
M15-M19 Arthrosis
0.907 0.093 0.000
R47.0 Dysphasia and aphasia
0.906 0.094 0.000
Z98.0 Intestinal bypass and anastomosis status
0.906 0.094 0.000
W20-W49 Exposure to inanimate mechanical forces
0.906 0.094 0.000
I77 Other disorders of arteries and arterioles
0.906 0.094 0.000
R47.8 Other and unspecified speech disturbances
0.904 0.096 0.000
J98.4 Other disorders of lung
0.903 0.097 0.000
S02 Fracture of skull and facial bones
0.901 0.099 0.000
J90 Pleural effusion, not elsewhere classified
0.900 0.100 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.898 0.102 0.000
Z51.3 Blood transfusion without reported diagnosis
0.896 0.104 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.895 0.105 0.000
Chapter XIV Diseases of the genitourinary system
0.894 0.106 0.000
Z50.0 Cardiac rehabilitation
0.891 0.109 0.000
M54 Dorsalgia
0.890 0.110 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.886 0.114 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.885 0.115 0.000
R49.0 Dysphonia
0.885 0.115 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.885 0.115 0.000
S60-S69 Injuries to the wrist and hand
0.884 0.116 0.000
Z57 Occupational exposure to risk-factors
0.883 0.117 0.000
M81 Osteoporosis without pathological fracture
0.883 0.117 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.881 0.119 0.000
M05-M14 Inflammatory polyarthropathies
0.880 0.120 0.000
Z12 Special screening examination for neoplasms
0.880 0.120 0.000
M54.9 Dorsalgia, unspecified
0.879 0.121 0.000
M16 Coxarthrosis [arthrosis of hip]
0.879 0.121 0.000
J92.9 Pleural plaque without asbestos
0.878 0.122 0.000
J40-J47 Chronic lower respiratory diseases
0.876 0.124 0.000
M16.9 Coxarthrosis, unspecified
0.875 0.125 0.000
I51.8 Other ill-defined heart diseases
0.872 0.128 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.872 0.128 0.000
Z80 Family history of malignant neoplasm
0.872 0.128 0.000
Z04 Examination and observation for other reasons
0.872 0.128 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.868 0.132 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.868 0.132 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.867 0.133 0.000
C18.6 Descending colon
0.865 0.135 0.000
M91-M94 Chondropathies
0.862 0.138 0.000
J98.8 Other specified respiratory disorders
0.862 0.138 0.000
I22 Subsequent myocardial infarction
0.857 0.143 0.000
I72 Other aneurysm
0.856 0.144 0.000
M86-M90 Other osteopathies
0.855 0.145 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.855 0.145 0.000
C18.0 Caecum
0.854 0.146 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.854 0.146 0.000
S06 Intracranial injury
0.852 0.148 0.000
Q50-Q56 Congenital malformations of genital organs
0.852 0.148 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.851 0.149 0.000
R60.9 Oedema, unspecified
0.850 0.150 0.000
N17-N19 Renal failure
0.848 0.152 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.848 0.152 0.000
I74 Arterial embolism and thrombosis
0.848 0.152 0.000
T40.2 Other opioids
0.847 0.153 0.000
J44 Other chronic obstructive pulmonary disease
0.847 0.153 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.846 0.154 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.843 0.157 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.842 0.158 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.842 0.158 0.000
N30-N39 Other diseases of urinary system
0.841 0.159 0.000
Z45.1 Adjustment and management of infusion pump
0.839 0.161 0.000
I51.7 Cardiomegaly
0.837 0.163 0.000
J92.0 Pleural plaque with presence of asbestos
0.836 0.164 0.000
Z50.5 Speech therapy
0.836 0.164 0.000
C21 Malignant neoplasm of anus and anal canal
0.835 0.164 0.000
M81.9 Osteoporosis, unspecified
0.835 0.165 0.000
I99 Other and unspecified disorders of circulatory system
0.835 0.165 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.833 0.167 0.000
R52 Pain, not elsewhere classified
0.833 0.167 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.832 0.168 0.000
W29 Contact with other powered hand tools and household machinery
0.831 0.169 0.000
Z43.3 Attention to colostomy
0.829 0.171 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.828 0.172 0.000
C50-C50 Malignant neoplasm of breast
0.827 0.173 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.825 0.175 0.000
R80 Isolated proteinuria
0.825 0.175 0.000
N32 Other disorders of bladder
0.825 0.175 0.000
M60-M63 Disorders of muscles
0.823 0.177 0.000
S02.1 Fracture of base of skull
0.823 0.177 0.000
Z95.2 Presence of prosthetic heart valve
0.823 0.177 0.000
S90-S99 Injuries to the ankle and foot
0.823 0.177 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.822 0.178 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.820 0.180 0.000
I51.4 Myocarditis, unspecified
0.819 0.181 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.819 0.181 0.000
R60.0 Localised oedema
0.819 0.181 0.000
Z95.4 Presence of other heart-valve replacement
0.817 0.183 0.000
C25 Malignant neoplasm of pancreas
0.817 0.183 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.814 0.186 0.000
N32.8 Other specified disorders of bladder
0.814 0.186 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.813 0.187 0.000
S01 Open wound of head
0.813 0.187 0.000
M65-M68 Disorders of synovium and tendon
0.812 0.188 0.000
R26 Abnormalities of gait and mobility
0.809 0.191 0.000
R25 Abnormal involuntary movements
0.807 0.193 0.000
Z51.1 Chemotherapy session for neoplasm
0.806 0.194 0.000
N18 Chronic renal failure
0.805 0.195 0.000
S79 Other and unspecified injuries of hip and thigh
0.804 0.196 0.000
I47 Paroxysmal tachycardia
0.804 0.196 0.000
Z51.8 Other specified medical care
0.802 0.198 0.000
I20.8 Other forms of angina pectoris
0.802 0.198 0.000
C17 Malignant neoplasm of small intestine
0.801 0.199 0.000
I24 Other acute ischaemic heart diseases
0.801 0.199 0.000
I05-I09 Chronic rheumatic heart diseases
0.800 0.200 0.000
X60-X84 Intentional self-harm
0.799 0.200 0.000
N99-N99 Other disorders of the genitourinary system
0.799 0.201 0.000
I46 Cardiac arrest
0.799 0.201 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.798 0.202 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.797 0.203 0.000
M06 Other rheumatoid arthritis
0.797 0.203 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.796 0.204 0.000
T79-T79 Certain early complications of trauma
0.796 0.204 0.000
I42.9 Cardiomyopathy, unspecified
0.796 0.204 0.000
Z80.3 Family history of malignant neoplasm of breast
0.796 0.204 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.795 0.205 0.000
M40-M43 Deforming dorsopathies
0.795 0.205 0.000
Z12.8 Special screening examination for neoplasm of other sites
0.794 0.206 0.000
Y83.4 Other reconstructive surgery
0.793 0.207 0.000
I25.2 Old myocardial infarction
0.793 0.207 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.792 0.208 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.790 0.210 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.790 0.210 0.000
Z42 Follow-up care involving plastic surgery
0.789 0.210 0.000
Z48 Other surgical follow-up care
0.789 0.211 0.000
M70-M79 Other soft tissue disorders
0.788 0.212 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.787 0.212 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.787 0.213 0.000
I36 Nonrheumatic tricuspid valve disorders
0.787 0.213 0.000
M84 Disorders of continuity of bone
0.786 0.214 0.000
S61 Open wound of wrist and hand
0.786 0.214 0.000
I70 Atherosclerosis
0.785 0.215 0.000
I42.0 Dilated cardiomyopathy
0.784 0.216 0.000
R73 Elevated blood glucose level
0.783 0.217 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.782 0.218 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.782 0.218 0.000
I37 Pulmonary valve disorders
0.782 0.218 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.782 0.218 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.781 0.219 0.000
R55 Syncope and collapse
0.781 0.219 0.000
Z04.3 Examination and observation following other accident
0.779 0.221 0.000
C18.2 Ascending colon
0.779 0.221 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.778 0.222 0.000
I35 Nonrheumatic aortic valve disorders
0.777 0.223 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.776 0.224 0.000
Z54 Convalescence
0.776 0.224 0.000
Z96.0 Presence of urogenital implants
0.776 0.224 0.000
R49.8 Other and unspecified voice disturbances
0.776 0.224 0.000
S05 Injury of eye and orbit
0.773 0.226 0.000
J47 Bronchiectasis
0.771 0.229 0.000
I20.1 Angina pectoris with documented spasm
0.769 0.231 0.000
Z89 Acquired absence of limb
0.769 0.231 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.769 0.231 0.000
I50 Heart failure
0.769 0.231 0.000
T51 Toxic effect of alcohol
0.768 0.232 0.000
R57 Shock, not elsewhere classified
0.768 0.232 0.000
S02.10 Fracture of base of skull (closed)
0.767 0.233 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.767 0.233 0.000
I44 Atrioventricular and left bundle-branch block
0.766 0.234 0.000
Z59 Problems related to housing and economic circumstances
0.766 0.234 0.000
I45 Other conduction disorders
0.765 0.235 0.000
V20-V29 Motorcycle rider injured in transport accident
0.765 0.235 0.000
Z58 Problems related to physical environment
0.765 0.235 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.765 0.235 0.000
D00-D09 In situ neoplasms
0.764 0.236 0.000
J94 Other pleural conditions
0.764 0.236 0.000
Z57.5 Occupational exposure to toxic agents in other industries
0.764 0.236 0.000
J91 Pleural effusion in conditions classified elsewhere
0.763 0.237 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.762 0.238 0.000
Z49 Care involving dialysis
0.762 0.238 0.000
Z99.3 Dependence on wheelchair
0.761 0.239 0.000
Z04.9 Examination and observation for unspecified reason
0.761 0.239 0.000
Z12.1 Special screening examination for neoplasm of intestinal tract
0.760 0.240 0.000
J60-J70 Lung diseases due to external agents
0.759 0.241 0.000
Z11.0 Special screening examination for intestinal infectious diseases
0.758 0.242 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.758 0.242 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.756 0.243 0.000
C10 Malignant neoplasm of oropharynx
0.756 0.244 0.000
Z43.6 Attention to other artificial openings of urinary tract
0.756 0.244 0.000
I60-I69 Cerebrovascular diseases
0.754 0.246 0.000
Z04.1 Examination and observation following transport accident
0.753 0.247 0.000
Z53.0 Procedure not carried out because of contraindication
0.752 0.248 0.000
Z99.2 Dependence on renal dialysis
0.751 0.249 0.000
N18.8 Other chronic renal failure
0.750 0.250 0.000
Z52 Donors of organs and tissues
0.749 0.251 0.000
N00-N08 Glomerular diseases
0.748 0.252 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.748 0.252 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.747 0.253 0.000
Z92.8 Personal history of other medical treatment
0.747 0.253 0.000
T23 Burn and corrosion of wrist and hand
0.746 0.254 0.000
M89 Other disorders of bone
0.746 0.254 0.000
W29.9 Unspecified place
0.745 0.255 0.000
I77.8 Other specified disorders of arteries and arterioles
0.745 0.255 0.000
I25.3 Aneurysm of heart
0.744 0.256 0.000
S72 Fracture of femur
0.743 0.256 0.000
Z43.0 Attention to tracheostomy
0.743 0.257 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.742 0.258 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.742 0.258 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.741 0.259 0.000
D60-D64 Aplastic and other anaemias
0.741 0.259 0.000
Y00-Y09 Assault
0.741 0.259 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.739 0.261 0.000
S67 Crushing injury of wrist and hand
0.738 0.262 0.000
S02.4 Fracture of malar and maxillary bones
0.738 0.262 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.737 0.263 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.737 0.263 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.736 0.264 0.000
W44 Foreign body entering into or through eye or natural orifice
0.735 0.265 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.734 0.266 0.000
S71 Open wound of hip and thigh
0.734 0.266 0.000
S09 Other and unspecified injuries of head
0.733 0.267 0.000
Z82.3 Family history of stroke
0.733 0.267 0.000
Z57.2 Occupational exposure to dust
0.732 0.268 0.000
M06.9 Rheumatoid arthritis, unspecified
0.732 0.268 0.000
X50-X57 Overexertion, travel and privation
0.731 0.268 0.000
V40-V49 Car occupant injured in transport accident
0.731 0.269 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.731 0.269 0.000
I31 Other diseases of pericardium
0.731 0.269 0.000
S61.8 Open wound of other parts of wrist and hand
0.730 0.270 0.000
C09 Malignant neoplasm of tonsil
0.729 0.271 0.000
Z50.8 Care involving use of rehabilitation procedures
0.729 0.271 0.000
R27 Other lack of coordination
0.728 0.272 0.000
S01.2 Open wound of nose
0.727 0.273 0.000
W00-W19 Falls
0.727 0.273 0.000
S70 Superficial injury of hip and thigh
0.727 0.273 0.000
Chapter I Certain infectious and parasitic diseases
0.726 0.274 0.000
S10-S19 Injuries to the neck
0.726 0.274 0.000
I72.9 Aneurysm of unspecified site
0.726 0.274 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.725 0.275 0.000
I71.0 Dissection of aorta [any part]
0.725 0.275 0.000
T39.0 Salicylates
0.724 0.276 0.000
R30-R39 Symptoms and signs involving the urinary system
0.724 0.276 0.000
Z43.8 Attention to other artificial openings
0.723 0.277 0.000
I33 Acute and subacute endocarditis
0.723 0.277 0.000
R73.0 Abnormal glucose tolerance test
0.723 0.277 0.000
N19 Unspecified renal failure
0.722 0.278 0.000
Z57.3 Occupational exposure to other air contaminants
0.721 0.279 0.000
M65 Synovitis and tenosynovitis
0.721 0.279 0.000
J09-J18 Influenza and pneumonia
0.720 0.280 0.000
S50-S59 Injuries to the elbow and forearm
0.719 0.281 0.000
M94 Other disorders of cartilage
0.719 0.281 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
Z50.6 Orthoptic training
0.717 0.283 0.000
Z50.3 Drug rehabilitation
0.717 0.283 0.000
C91 Lymphoid leukaemia
0.717 0.283 0.000
C23 Malignant neoplasm of gallbladder
0.717 0.283 0.000
R63.1 Polydipsia
0.717 0.283 0.000
C18.8 Overlapping lesion of colon
0.716 0.283 0.000
T33-T35 Frostbite
0.716 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.283 0.000
Z51.9 Medical care, unspecified
0.716 0.283 0.000
Z51.6 Desensitisation to allergens
0.716 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
Z43.1 Attention to gastrostomy
0.716 0.284 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.284 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.716 0.284 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.715 0.285 0.000
I23 Certain current complications following acute myocardial infarction
0.715 0.285 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.715 0.285 0.000
N18.0 End-stage renal disease
0.715 0.285 0.000
S79.9 Unspecified injury of hip and thigh
0.714 0.285 0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
0.714 0.286 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.713 0.287 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.712 0.288 0.000
I52 Other heart disorders in diseases classified elsewhere
0.712 0.288 0.000
I48 Atrial fibrillation and flutter
0.712 0.288 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.712 0.288 0.000
I41 Myocarditis in diseases classified elsewhere
0.712 0.288 0.000
I40 Acute myocarditis
0.712 0.288 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.712 0.288 0.000
I32 Pericarditis in diseases classified elsewhere
0.712 0.288 0.000
T21 Burn and corrosion of trunk
0.712 0.288 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.712 0.288 0.000
C01 Malignant neoplasm of base of tongue
0.712 0.288 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.711 0.289 0.000
Z43.5 Attention to cyctostomy
0.710 0.290 0.000
R71 Abnormality of red blood cells
0.709 0.291 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.709 0.291 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.709 0.291 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.709 0.291 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.709 0.291 0.000
M53 Other dorsopathies, not elsewhere classified
0.709 0.291 0.000
Z99.9 Dependence on unspecified enabling machine and device
0.708 0.292 0.000
Z99.4 Dependence on artificial heart
0.708 0.292 0.000
Z99.0 Dependence on aspirator
0.708 0.292 0.000
M00-M03 Infectious arthropathies
0.708 0.292 0.000
R33 Retention of urine
0.708 0.292 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.707 0.293 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.707 0.293 0.000
Y35-Y36 Legal intervention and operations of war
0.707 0.293 0.000
Y10-Y34 Event of undetermined intent
0.707 0.293 0.000
X85-X99 Assault
0.707 0.293 0.000
X30-X39 Exposure to forces of nature
0.707 0.293 0.000
X20-X29 Contact with venomous animals and plants
0.707 0.293 0.000
X10-X19 Contact with heat and hot substances
0.707 0.293 0.000
X00-X09 Exposure to smoke, fire and flames
0.707 0.293 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.707 0.293 0.000
W75-W84 Other accidental threats to breathing
0.707 0.293 0.000
W65-W74 Accidental drowning and submersion
0.707 0.293 0.000
W50-W64 Exposure to animate mechanical forces
0.707 0.293 0.000
V98-V99 Other and unspecified transport accidents
0.707 0.293 0.000
V95-V97 Air and space transport accidents
0.707 0.293 0.000
V90-V94 Water transport accidents
0.707 0.293 0.000
V70-V79 Bus occupant injured in transport accident
0.707 0.293 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.707 0.293 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.707 0.293 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.707 0.293 0.000
V01-V09 Pedestrian injured in transport accident
0.707 0.293 0.000
N32.3 Diverticulum of bladder
0.706 0.294 0.000
R25.2 Cramp and spasm
0.706 0.294 0.000
C18.1 Appendix
0.704 0.296 0.000
C50 Malignant neoplasm of breast
0.704 0.296 0.000
Z43.4 Attention to other artificial openings of digestive tract
0.704 0.296 0.000
N18.4 Chronic kidney disease, stage 4
0.704 0.296 0.000
C07 Malignant neoplasm of parotid gland
0.704 0.296 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.703 0.296 0.000
R62 Lack of expected normal physiological development
0.703 0.296 0.000
R64 Cachexia
0.703 0.296 0.000
Z43.9 Attention to unspecified artificial opening
0.703 0.297 0.000
Z43.7 Attention to artificial vagina
0.703 0.297 0.000
M07 Psoriatic and enteropathic arthropathies
0.703 0.297 0.000
S06.5 Traumatic subdural haemorrhage
0.701 0.299 0.000
S08 Traumatic amputation of part of head
0.700 0.299 0.000
S07 Crushing injury of head
0.700 0.299 0.000
S04 Injury of cranial nerves
0.700 0.299 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.700 0.299 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.700 0.300 0.000
Z45.9 Adjustment and management of unspecified implanted device
0.700 0.300 0.000
Z45.3 Adjustment and management of implanted hearing device
0.700 0.300 0.000
Q80-Q89 Other congenital malformations
0.699 0.301 0.000
J96 Respiratory failure, not elsewhere classified
0.699 0.301 0.000
I44.2 Atrioventricular block, complete
0.699 0.301 0.000
M05 Seropositive rheumatoid arthritis
0.699 0.301 0.000
Z96.9 Presence of functional implant, unspecified
0.698 0.301 0.000
Z96.5 Presence of tooth-root and mandibular implants
0.698 0.301 0.000
Z96.4 Presence of endocrine implants
0.698 0.301 0.000
Z96.3 Presence of artificial larynx
0.698 0.301 0.000
Z96.2 Presence of otological and audiological implants
0.698 0.301 0.000
S64 Injury of nerves at wrist and hand level
0.698 0.302 0.000
M62 Other disorders of muscle
0.697 0.303 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.696 0.304 0.000
M77 Other enthesopathies
0.696 0.304 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.695 0.304 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.695 0.305 0.000
D69 Purpura and other haemorrhagic conditions
0.695 0.305 0.000
Chapter XXII Codes for special purposes
0.694 0.306 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.694 0.306 0.000
Y40 Systemic antibiotics
0.693 0.307 0.000
I25.6 Silent myocardial ischaemia
0.693 0.307 0.000
I25.4 Coronary artery aneurysm
0.693 0.307 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.693 0.307 0.000
S60 Superficial injury of wrist and hand
0.693 0.307 0.000
Z44 Fitting and adjustment of external prosthetic device
0.693 0.307 0.000
I51.5 Myocardial degeneration
0.692 0.308 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.692 0.308 0.000
I51.0 Cardiac septal defect, acquired
0.692 0.308 0.000
J98.9 Respiratory disorder, unspecified
0.692 0.308 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.692 0.308 0.000
I72.4 Aneurysm of artery of lower extremity
0.692 0.308 0.000
D68 Other coagulation defects
0.691 0.309 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.690 0.309 0.000
Z80.8 Family history of malignant neoplasm of other organs or systems
0.690 0.310 0.000
T40.6 Other and unspecified narcotics
0.689 0.310 0.000
I51.6 Cardiovascular disease, unspecified
0.689 0.311 0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs
0.689 0.311 0.000
I77.6 Arteritis, unspecified
0.688 0.312 0.000
R63.4 Abnormal weight loss
0.686 0.314 0.000
Z98.1 Arthrodesis status
0.686 0.314 0.000
N02 Recurrent and persistent haematuria
0.686 0.314 0.000
C16 Malignant neoplasm of stomach
0.686 0.314 0.000
I47.2 Ventricular tachycardia
0.686 0.314 0.000
S06.0 Concussion
0.685 0.315 0.000
M45-M49 Spondylopathies
0.685 0.315 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.685 0.315 0.000
W29.5 Trade and service area
0.684 0.316 0.000
T51.9 Alcohol, unspecified
0.683 0.317 0.000
N30 Cystitis
0.683 0.317 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.682 0.318 0.000
Z92.9 Personal history of medical treatment, unspecified
0.682 0.318 0.000
Z92.5 Personal history of rehabilitation measures
0.682 0.318 0.000
R52.1 Chronic intractable pain
0.682 0.318 0.000
I77.0 Arteriovenous fistula, acquired
0.682 0.318 0.000
M16.3 Other dysplastic coxarthrosis
0.682 0.318 0.000
I67 Other cerebrovascular diseases
0.682 0.318 0.000
R61 Hyperhidrosis
0.681 0.319 0.000
J98.6 Disorders of diaphragm
0.681 0.319 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.681 0.319 0.000
J98.3 Compensatory emphysema
0.681 0.319 0.000
J98.2 Interstitial emphysema
0.681 0.319 0.000
S68 Traumatic amputation of wrist and hand
0.681 0.319 0.000
Q53 Undescended testicle
0.681 0.319 0.000
V80-V89 Other land transport accidents
0.680 0.320 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.680 0.320 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.680 0.320 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.680 0.320 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.680 0.320 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.680 0.320 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.680 0.320 0.000
T36 Poisoning by systemic antibiotics
0.680 0.320 0.000
C18.4 Transverse colon
0.680 0.320 0.000
Z65 Problems related to other psychosocial circumstances
0.679 0.320 0.000
Z64 Problems related to certain psychosocial circumstances
0.679 0.320 0.000
Z62 Other problems related to upbringing
0.679 0.320 0.000
Z61 Problems related to negative life events in childhood
0.679 0.320 0.000
Z56 Problems related to employment and unemployment
0.679 0.320 0.000
Z55 Problems related to education and literacy
0.679 0.320 0.000
N60-N64 Disorders of breast
0.678 0.322 0.000
R63.6 Insufficient intake of food and water due to self neglect
0.678 0.322 0.000
R63.5 Abnormal weight gain
0.678 0.322 0.000
R63.3 Feeding difficulties and mismanagement
0.678 0.322 0.000
R63.2 Polyphagia
0.678 0.322 0.000
Z12.4 Special screening examination for neoplasm of cervix
0.678 0.322 0.000
I35.0 Aortic (valve) stenosis
0.678 0.322 0.000
Z96.7 Presence of other bone and tendon implants
0.677 0.322 0.000
M50 Cervical disk disorders
0.677 0.323 0.000
D63.0 Anaemia in neoplastic disease
0.677 0.323 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.676 0.324 0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.676 0.324 0.000
R49.2 Hypernasality and hyponasality
0.676 0.324 0.000
R49.1 Aphonia
0.676 0.324 0.000
C21.1 Anal canal
0.675 0.325 0.000
R59 Enlarged lymph nodes
0.674 0.326 0.000
R56.0 Febrile convulsions
0.673 0.327 0.000
I05 Rheumatic mitral valve diseases
0.673 0.327 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.673 0.327 0.000
M83 Adult osteomalacia
0.672 0.328 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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