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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs76964416
log Bayes Factor = 17.3421
Chromosome 5   position 141,526,554  (GRCh37) Explore rs76964416 on Ensembl!
Variant rs76964416 is part of Cluster X0232

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
0.999 0.001 0.000
Chapter V Mental and behavioural disorders
0.997 0.003 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.997 0.003 0.000
Chapter X Diseases of the respiratory system
0.996 0.004 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.995 0.005 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.995 0.005 0.000
Chapter VI Diseases of the nervous system
0.994 0.006 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.993 0.007 0.000
Chapter VIII Diseases of the ear and mastoid process
0.991 0.009 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.990 0.010 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.988 0.012 0.000
R06 Abnormalities of breathing
0.987 0.013 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.986 0.014 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.983 0.017 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.981 0.019 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.980 0.020 0.000
R06.5 Mouth breathing
0.979 0.021 0.000
L03 Cellulitis
0.979 0.021 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.974 0.026 0.000
D50-D53 Nutritional anaemias
0.971 0.029 0.000
J30-J39 Other diseases of upper respiratory tract
0.968 0.032 0.000
E10-E14 Diabetes mellitus
0.968 0.032 0.000
Chapter XIV Diseases of the genitourinary system
0.967 0.033 0.000
O42 Premature rupture of membranes
0.966 0.034 0.000
H60-H62 Diseases of external ear
0.964 0.036 0.000
J33 Nasal polyp
0.962 0.038 0.000
N17-N19 Renal failure
0.960 0.040 0.000
D50 Iron deficiency anaemia
0.957 0.043 0.000
J40-J47 Chronic lower respiratory diseases
0.957 0.043 0.000
J45 Asthma
0.955 0.045 0.000
J33.0 Polyp of nasal cavity
0.954 0.046 0.000
J45.9 Asthma, unspecified
0.953 0.047 0.000
D50.8 Other iron deficiency anaemias
0.951 0.049 0.000
L20-L30 Dermatitis and eczema
0.950 0.050 0.000
Y43 Primarily systemic agents
0.948 0.052 0.000
R06.0 Dyspnoea
0.948 0.052 0.000
L60-L75 Disorders of skin appendages
0.947 0.053 0.000
E11 Non-insulin-dependent diabetes mellitus
0.942 0.058 0.000
F03 Unspecified dementia
0.940 0.060 0.000
N17 Acute renal failure
0.938 0.062 0.000
Chapter I Certain infectious and parasitic diseases
0.929 0.071 0.000
G30-G32 Other degenerative diseases of the nervous system
0.926 0.074 0.000
R50-R69 General symptoms and signs
0.926 0.074 0.000
Chapter XXII Codes for special purposes
0.924 0.076 0.000
N17.9 Acute renal failure, unspecified
0.923 0.077 0.000
R60 Oedema, not elsewhere classified
0.916 0.084 0.000
Y43.3 Other antineoplastic drugs
0.916 0.084 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.916 0.084 0.000
F30-F39 Mood [affective] disorders
0.914 0.086 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.911 0.089 0.000
E50-E64 Other nutritional deficiencies
0.908 0.092 0.000
L03.3 Cellulitis of trunk
0.907 0.093 0.000
L60 Nail disorders
0.907 0.093 0.000
H65-H75 Diseases of middle ear and mastoid
0.906 0.094 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.906 0.094 0.000
W00-W19 Falls
0.906 0.094 0.000
R02 Gangrene, not elsewhere classified
0.905 0.095 0.000
Y40 Systemic antibiotics
0.903 0.097 0.000
R60.0 Localised oedema
0.901 0.099 0.000
H60 Otitis externa
0.898 0.102 0.000
L29 Pruritus
0.897 0.103 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.892 0.108 0.000
J90-J94 Other diseases of pleura
0.891 0.109 0.000
J33.8 Other polyp of sinus
0.890 0.110 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.890 0.110 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.889 0.111 0.000
N10-N16 Renal tubulo-interstitial diseases
0.886 0.114 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.886 0.114 0.000
H61 Other disorders of external ear
0.886 0.114 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.884 0.116 0.000
E10 Insulin-dependent diabetes mellitus
0.883 0.117 0.000
R27 Other lack of coordination
0.881 0.119 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.881 0.119 0.000
R54 Senility
0.876 0.124 0.000
G30 Alzheimer's disease
0.872 0.128 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.868 0.132 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.865 0.135 0.000
L60.0 Ingrowing nail
0.864 0.136 0.000
L03.0 Cellulitis of finger and toe
0.864 0.136 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.863 0.137 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.860 0.140 0.000
R29.6 Tendency to fall, not elsewhere classified
0.858 0.142 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.855 0.145 0.000
F31 Bipolar affective disorder
0.854 0.146 0.000
R03.1 Nonspecific low blood-pressure reading
0.854 0.146 0.000
O42.9 Premature rupture of membranes, unspecified
0.853 0.147 0.000
L03.8 Cellulitis of other sites
0.851 0.149 0.000
R47-R49 Symptoms and signs involving speech and voice
0.851 0.149 0.000
W20-W49 Exposure to inanimate mechanical forces
0.849 0.151 0.000
E11.3 With ophthalmic complications
0.849 0.151 0.000
G90-G99 Other disorders of the nervous system
0.849 0.151 0.000
N19 Unspecified renal failure
0.848 0.152 0.000
E11.4 With neurological complications
0.848 0.152 0.000
A30-A49 Other bacterial diseases
0.847 0.153 0.000
G20-G26 Extrapyramidal and movement disorders
0.846 0.154 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.844 0.156 0.000
V40-V49 Car occupant injured in transport accident
0.844 0.156 0.000
L73 Other follicular disorders
0.842 0.158 0.000
T66-T78 Other and unspecified effects of external causes
0.842 0.158 0.000
L03.9 Cellulitis, unspecified
0.840 0.160 0.000
S40-S49 Injuries to the shoulder and upper arm
0.837 0.163 0.000
F00 Dementia in Alzheimer's disease
0.835 0.165 0.000
H90-H95 Other disorders of ear
0.834 0.166 0.000
G30.9 Alzheimer's disease, unspecified
0.833 0.167 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.832 0.168 0.000
J34 Other disorders of nose and nasal sinuses
0.830 0.170 0.000
D60-D64 Aplastic and other anaemias
0.827 0.173 0.000
O80-O84 Delivery
0.826 0.174 0.000
R52 Pain, not elsewhere classified
0.819 0.181 0.000
O46.9 Antepartum haemorrhage, unspecified
0.817 0.183 0.000
N20-N23 Urolithiasis
0.815 0.185 0.000
J91 Pleural effusion in conditions classified elsewhere
0.814 0.186 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.814 0.186 0.000
O43 Placental disorders
0.814 0.186 0.000
E55 Vitamin D deficiency
0.814 0.186 0.000
L08 Other local infections of skin and subcutaneous tissue
0.814 0.186 0.000
N10 Acute tubulo-interstitial nephritis
0.813 0.187 0.000
H60.9 Otitis externa, unspecified
0.812 0.188 0.000
O40 Polyhydramnios
0.812 0.188 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.811 0.189 0.000
H66 Suppurative and unspecified otitis media
0.806 0.194 0.000
S00-S09 Injuries to the head
0.806 0.194 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.805 0.195 0.000
S10-S19 Injuries to the neck
0.805 0.195 0.000
N18 Chronic renal failure
0.802 0.198 0.000
E10.9 Without complications
0.801 0.199 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.799 0.200 0.000
E11.5 With peripheral circulatory complications
0.796 0.204 0.000
E70-E90 Metabolic disorders
0.795 0.205 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.795 0.205 0.000
O41 Other disorders of amniotic fluid and membranes
0.794 0.206 0.000
R27.0 Ataxia, unspecified
0.792 0.208 0.000
V10-V19 Pedal cyclist injured in transport accident
0.790 0.210 0.000
J09-J18 Influenza and pneumonia
0.789 0.211 0.000
D55-D59 Haemolytic anaemias
0.788 0.211 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.786 0.214 0.000
F60-F69 Disorders of adult personality and behaviour
0.786 0.214 0.000
R05 Cough
0.785 0.214 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.784 0.216 0.000
B15-B19 Viral hepatitis
0.783 0.217 0.000
L05 Pilonidal cyst
0.782 0.218 0.000
R49 Voice disturbances
0.782 0.218 0.000
E11.6 With other specified complications
0.781 0.219 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.780 0.219 0.000
L29.9 Pruritus, unspecified
0.780 0.220 0.000
O85-O92 Complications predominantly related to the puerperium
0.777 0.223 0.000
G62 Other polyneuropathies
0.777 0.223 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.774 0.226 0.000
J34.2 Deviated nasal septum
0.774 0.226 0.000
L98.0 Pyogenic granuloma
0.772 0.228 0.000
T79-T79 Certain early complications of trauma
0.771 0.229 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.771 0.229 0.000
J92 Pleural plaque
0.769 0.231 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.768 0.232 0.000
H92 Otalgia and effusion of ear
0.768 0.232 0.000
Y40.8 Other systemic antibiotics
0.766 0.234 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.765 0.235 0.000
D80-D89 Certain disorders involving the immune mechanism
0.765 0.235 0.000
F02 Dementia in other diseases classified elsewhere
0.763 0.237 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.763 0.237 0.000
R94 Abnormal results of function studies
0.763 0.237 0.000
F01 Vascular dementia
0.763 0.237 0.000
Y40.0 Penicillins
0.762 0.238 0.000
R06.1 Stridor
0.762 0.238 0.000
X50-X57 Overexertion, travel and privation
0.761 0.239 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.759 0.241 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.759 0.241 0.000
R25 Abnormal involuntary movements
0.757 0.242 0.000
E53 Deficiency of other B group vitamins
0.757 0.243 0.000
L29.0 Pruritus ani
0.757 0.243 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.757 0.243 0.000
D69 Purpura and other haemorrhagic conditions
0.757 0.243 0.000
F31.9 Bipolar affective disorder, unspecified
0.757 0.243 0.000
G50 Disorders of trigeminal nerve
0.756 0.244 0.000
H60.1 Cellulitis of external ear
0.756 0.244 0.000
L30 Other dermatitis
0.755 0.245 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.755 0.245 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.755 0.245 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.754 0.246 0.000
W50-W64 Exposure to animate mechanical forces
0.754 0.246 0.000
N99-N99 Other disorders of the genitourinary system
0.752 0.248 0.000
R60.9 Oedema, unspecified
0.751 0.249 0.000
Q80-Q89 Other congenital malformations
0.750 0.250 0.000
W07 Fall involving chair
0.749 0.251 0.000
L29.2 Pruritus vulvae
0.749 0.251 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.748 0.252 0.000
L73.2 Hidradenitis suppurativa
0.747 0.253 0.000
S80-S89 Injuries to the knee and lower leg
0.746 0.253 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.746 0.254 0.000
E55.9 Vitamin D deficiency, unspecified
0.746 0.254 0.000
Q50-Q56 Congenital malformations of genital organs
0.744 0.256 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.743 0.257 0.000
T78 Adverse effects, not elsewhere classified
0.743 0.257 0.000
N18.3 Chronic kidney disease, stage 3
0.742 0.258 0.000
W10 Fall on and from stairs and steps
0.739 0.261 0.000
H61.0 Perichondritis of external ear
0.739 0.261 0.000
Y44 Agents primarily affecting blood constituents
0.739 0.261 0.000
L60.9 Nail disorder, unspecified
0.737 0.263 0.000
L89 Decubitus ulcer
0.736 0.264 0.000
Q00-Q07 Congenital malformations of the nervous system
0.736 0.264 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.736 0.264 0.000
X20-X29 Contact with venomous animals and plants
0.736 0.264 0.000
H66.9 Otitis media, unspecified
0.734 0.266 0.000
Y57 Other and unspecified drugs and medicaments
0.733 0.267 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.733 0.267 0.000
R94.5 Abnormal results of liver function studies
0.733 0.267 0.000
R49.0 Dysphonia
0.732 0.268 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.732 0.268 0.000
G20 Parkinson's disease
0.732 0.268 0.000
V49 Car occupant injured in other and unspecified transport accidents
0.732 0.268 0.000
H61.3 Acquired stenosis of external ear canal
0.731 0.268 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.731 0.268 0.000
B35-B49 Mycoses
0.731 0.269 0.000
F00.9 Dementia in Alzheimer's disease, unspecified
0.731 0.269 0.000
F10.0 Acute intoxication
0.731 0.269 0.000
W22 Striking against or struck by other objects
0.731 0.269 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.730 0.270 0.000
R59 Enlarged lymph nodes
0.730 0.270 0.000
H61.2 Impacted cerumen
0.729 0.271 0.000
R60.1 Generalised oedema
0.729 0.271 0.000
H74 Other disorders of middle ear and mastoid
0.729 0.271 0.000
X60-X84 Intentional self-harm
0.727 0.272 0.000
F80-F89 Disorders of psychological development
0.727 0.273 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.727 0.273 0.000
J95-J99 Other diseases of the respiratory system
0.726 0.274 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.725 0.275 0.000
A41 Other septicaemia
0.724 0.276 0.000
L98.4 Chronic ulcer of skin, not elsewhere classified
0.723 0.277 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.723 0.277 0.000
S90-S99 Injuries to the ankle and foot
0.721 0.279 0.000
R68 Other general symptoms and signs
0.721 0.279 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.721 0.279 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.721 0.279 0.000
B99-B99 Other infectious diseases
0.719 0.281 0.000
J45.0 Predominantly allergic asthma
0.719 0.281 0.000
Y52 Agents primarily affecting the cardiovascular system
0.717 0.283 0.000
J42 Unspecified chronic bronchitis
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
L10-L14 Bullous disorders
0.717 0.283 0.000
V80-V89 Other land transport accidents
0.716 0.283 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.716 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.716 0.284 0.000
Y10-Y34 Event of undetermined intent
0.716 0.284 0.000
Y00-Y09 Assault
0.716 0.284 0.000
X85-X99 Assault
0.716 0.284 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.716 0.284 0.000
X30-X39 Exposure to forces of nature
0.716 0.284 0.000
X10-X19 Contact with heat and hot substances
0.716 0.284 0.000
X00-X09 Exposure to smoke, fire and flames
0.716 0.284 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.716 0.284 0.000
W75-W84 Other accidental threats to breathing
0.716 0.284 0.000
W65-W74 Accidental drowning and submersion
0.716 0.284 0.000
V98-V99 Other and unspecified transport accidents
0.716 0.284 0.000
V95-V97 Air and space transport accidents
0.716 0.284 0.000
V90-V94 Water transport accidents
0.716 0.284 0.000
V70-V79 Bus occupant injured in transport accident
0.716 0.284 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.716 0.284 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.716 0.284 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.716 0.284 0.000
V01-V09 Pedestrian injured in transport accident
0.716 0.284 0.000
F10.3 Withdrawal state
0.716 0.284 0.000
G60 Hereditary and idiopathic neuropathy
0.716 0.284 0.000
R26 Abnormalities of gait and mobility
0.715 0.284 0.000
R06.6 Hiccough
0.715 0.285 0.000
W18 Other fall on same level
0.715 0.285 0.000
R52.2 Other chronic pain
0.715 0.285 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.715 0.285 0.000
F70-F79 Mental retardation
0.715 0.285 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.715 0.285 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.714 0.286 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.714 0.286 0.000
L04 Acute lymphadenitis
0.713 0.287 0.000
L01 Impetigo
0.713 0.287 0.000
L00 Staphylococcal scalded skin syndrome
0.713 0.287 0.000
L28 Lichen simplex chronicus and prurigo
0.713 0.287 0.000
Y43.1 Antineoplastic antimetabolites
0.712 0.287 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.712 0.288 0.000
N00-N08 Glomerular diseases
0.711 0.289 0.000
J60-J70 Lung diseases due to external agents
0.711 0.289 0.000
F30 Manic episode
0.710 0.290 0.000
H70 Mastoiditis and related conditions
0.709 0.291 0.000
L82 Seborrhoeic keratosis
0.709 0.291 0.000
Y59 Other and unspecified vaccines and biological substances
0.708 0.292 0.000
Y58 Bacterial vaccines
0.708 0.292 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.708 0.292 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.708 0.292 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.708 0.292 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.708 0.292 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.708 0.292 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.708 0.292 0.000
Y48 Anaesthetics and therapeutic gases
0.708 0.292 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.708 0.292 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.708 0.292 0.000
R06.7 Sneezing
0.708 0.292 0.000
R06.3 Periodic breathing
0.708 0.292 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.707 0.293 0.000
L65 Other nonscarring hair loss
0.705 0.295 0.000
O45 Premature separation of placenta [abruptio placentae]
0.704 0.295 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.704 0.295 0.000
O33 Maternal care for known or suspected disproportion
0.704 0.295 0.000
O31 Complications specific to multiple gestation
0.704 0.295 0.000
J92.0 Pleural plaque with presence of asbestos
0.704 0.296 0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.704 0.296 0.000
E13 Other specified diabetes mellitus
0.703 0.297 0.000
T33-T35 Frostbite
0.703 0.297 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.703 0.297 0.000
T00-T07 Injuries involving multiple body regions
0.703 0.297 0.000
G90 Disorders of autonomic nervous system
0.703 0.297 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.703 0.297 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.703 0.297 0.000
F09 Unspecified organic or symptomatic mental disorder
0.703 0.297 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.703 0.297 0.000
H72 Perforation of tympanic membrane
0.702 0.298 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.701 0.299 0.000
O44 Placenta praevia
0.700 0.300 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.700 0.300 0.000
L71 Rosacea
0.699 0.301 0.000
R27.8 Other and unspecified lack of coordination
0.698 0.302 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.698 0.302 0.000
E40-E46 Malnutrition
0.697 0.303 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.697 0.303 0.000
D53 Other nutritional anaemias
0.696 0.304 0.000
H69 Other disorders of Eustachian tube
0.696 0.304 0.000
L98.8 Other specified disorders of skin and subcutaneous tissue
0.696 0.304 0.000
O43.1 Malformation of placenta
0.695 0.304 0.000
Y40.1 Cefalosporins and other -lactam antibiotics
0.695 0.305 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.695 0.305 0.000
E88 Other metabolic disorders
0.695 0.305 0.000
F10.2 Dependence syndrome
0.695 0.305 0.000
U80 Agent resistant to penicillin and related antibiotics
0.695 0.305 0.000
J37 Chronic laryngitis and laryngotracheitis
0.694 0.306 0.000
E12 Malnutrition-related diabetes mellitus
0.694 0.306 0.000
H92.0 Otalgia
0.694 0.306 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.693 0.307 0.000
O42.2 Premature rupture of membranes, labour delayed by therapy
0.692 0.308 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.692 0.308 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.692 0.308 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.692 0.308 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.691 0.308 0.000
J46 Status asthmaticus
0.691 0.309 0.000
G59.0 Diabetic mononeuropathy
0.690 0.310 0.000
G57 Mononeuropathies of lower limb
0.690 0.310 0.000
J33.1 Polypoid sinus degeneration
0.690 0.310 0.000
D51 Vitamin B12 deficiency anaemia
0.689 0.311 0.000
A48 Other bacterial diseases, not elsewhere classified
0.689 0.311 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.688 0.311 0.000
N21 Calculus of lower urinary tract
0.688 0.312 0.000
S70-S79 Injuries to the hip and thigh
0.687 0.313 0.000
W06 Fall involving bed
0.687 0.313 0.000
U88 Agent resistant to multiple antibiotics
0.687 0.313 0.000
D50.1 Sideropenic dysphagia
0.686 0.314 0.000
J41 Simple and mucopurulent chronic bronchitis
0.686 0.314 0.000
E11.1 With ketoacidosis
0.685 0.315 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.685 0.315 0.000
G70-G73 Diseases of myoneural junction and muscle
0.684 0.315 0.000
J45.8 Mixed asthma
0.684 0.315 0.000
J45.1 Nonallergic asthma
0.684 0.315 0.000
H90 Conductive and sensorineural hearing loss
0.684 0.316 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.683 0.317 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.683 0.317 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.682 0.318 0.000
S50-S59 Injuries to the elbow and forearm
0.682 0.318 0.000
O30 Multiple gestation
0.682 0.318 0.000
O24 Diabetes mellitus in pregnancy
0.681 0.319 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.681 0.319 0.000
L25 Unspecified contact dermatitis
0.681 0.319 0.000
L24 Irritant contact dermatitis
0.681 0.319 0.000
L23 Allergic contact dermatitis
0.681 0.319 0.000
L21 Seborrhoeic dermatitis
0.681 0.319 0.000
L20 Atopic dermatitis
0.681 0.319 0.000
L26 Exfoliative dermatitis
0.681 0.319 0.000
L22 Diaper [napkin] dermatitis
0.681 0.319 0.000
Y43.9 Primarily systemic agent, unspecified
0.680 0.320 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.680 0.320 0.000
Y43.6 Enzymes, not elsewhere classified
0.680 0.320 0.000
Y43.5 Acidifying and alkalising agents
0.680 0.320 0.000
Y43.2 Antineoplastic natural products
0.680 0.320 0.000
Y43.0 Antiallergic and antiemetic drugs
0.680 0.320 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.680 0.320 0.000
L90 Atrophic disorders of skin
0.679 0.321 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.679 0.321 0.000
D61 Other aplastic anaemias
0.679 0.321 0.000
L75 Apocrine sweat disorders
0.679 0.321 0.000
L74 Eccrine sweat disorders
0.679 0.321 0.000
L70 Acne
0.679 0.321 0.000
L68 Hypertrichosis
0.679 0.321 0.000
L67 Hair colour and hair shaft abnormalities
0.679 0.321 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.679 0.321 0.000
L64 Androgenic alopecia
0.679 0.321 0.000
L63 Alopecia areata
0.679 0.321 0.000
L62 Nail disorders in diseases classified elsewhere
0.679 0.321 0.000
E83 Disorders of mineral metabolism
0.678 0.322 0.000
W29 Contact with other powered hand tools and household machinery
0.678 0.322 0.000
G58 Other mononeuropathies
0.677 0.323 0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
0.677 0.323 0.000
Y43.4 Immunosuppressive agents
0.675 0.325 0.000
E11.8 With unspecified complications
0.675 0.325 0.000
E11.7 With multiple complications
0.675 0.325 0.000
E11.0 With coma
0.675 0.325 0.000
L93 Lupus erythematosus
0.675 0.325 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.673 0.327 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.673 0.327 0.000
S01 Open wound of head
0.673 0.327 0.000
N17.8 Other acute renal failure
0.672 0.327 0.000
N17.2 Acute renal failure with medullary necrosis
0.672 0.327 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.672 0.327 0.000
N17.0 Acute renal failure with tubular necrosis
0.672 0.327 0.000
N18.4 Chronic kidney disease, stage 4
0.672 0.328 0.000
U89 Agent resistant to other and unspecified antibiotics
0.671 0.329 0.000
F99-F99 Unspecified mental disorder
0.670 0.330 0.000
R58 Haemorrhage, not elsewhere classified
0.669 0.331 0.000
W19 Unspecified fall
0.669 0.331 0.000
F33 Recurrent depressive disorder
0.668 0.332 0.000
G62.8 Other specified polyneuropathies
0.668 0.332 0.000
S19 Other and unspecified injuries of neck
0.668 0.332 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.666 0.334 0.000
B65-B83 Helminthiases
0.666 0.334 0.000
B50-B64 Protozoal diseases
0.666 0.334 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.666 0.334 0.000
A75-A79 Rickettsioses
0.666 0.334 0.000
A70-A74 Other diseases caused by chlamydiae
0.666 0.334 0.000
A65-A69 Other spirochaetal diseases
0.666 0.334 0.000
A20-A28 Certain zoonotic bacterial diseases
0.666 0.334 0.000
A15-A19 Tuberculosis
0.666 0.334 0.000
O36 Maternal care for other known or suspected foetal problems
0.666 0.334 0.000
E16 Other disorders of pancreatic internal secretion
0.666 0.334 0.000
S82 Fracture of lower leg, including ankle
0.665 0.335 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.664 0.336 0.000
L27 Dermatitis due to substances taken internally
0.664 0.336 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.664 0.336 0.000
R62 Lack of expected normal physiological development
0.664 0.336 0.000
R57 Shock, not elsewhere classified
0.664 0.336 0.000
R64 Cachexia
0.664 0.336 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.664 0.336 0.000
N60-N64 Disorders of breast
0.664 0.336 0.000
E10.2 With renal complications
0.663 0.337 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.662 0.337 0.000
R06.4 Hyperventilation
0.662 0.338 0.000
B18 Chronic viral hepatitis
0.661 0.338 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.661 0.339 0.000
O80 Single spontaneous delivery
0.661 0.339 0.000
G51 Facial nerve disorders
0.660 0.340 0.000
G50.0 Trigeminal neuralgia
0.659 0.341 0.000
O41.0 Oligohydramnios
0.659 0.341 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.658 0.342 0.000
E10.1 With ketoacidosis
0.658 0.342 0.000
N11 Chronic tubulo-interstitial nephritis
0.658 0.342 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.657 0.343 0.000
Q35-Q37 Cleft lip and cleft palate
0.657 0.343 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.657 0.343 0.000
O82 Single delivery by Caesarean section
0.657 0.343 0.000
L73.9 Follicular disorder, unspecified
0.656 0.343 0.000
J30 Vasomotor and allergic rhinitis
0.656 0.344 0.000
V20-V29 Motorcycle rider injured in transport accident
0.656 0.344 0.000
F38 Other mood [affective] disorders
0.656 0.344 0.000
F34 Persistent mood [affective] disorders
0.656 0.344 0.000
F39 Unspecified mood [affective] disorder
0.656 0.344 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.655 0.344 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.655 0.345 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.655 0.345 0.000
N23 Unspecified renal colic
0.654 0.346 0.000
D68 Other coagulation defects
0.653 0.346 0.000
J34.3 Hypertrophy of nasal turbinates
0.653 0.347 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.653 0.347 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.653 0.347 0.000
L94 Other localised connective tissue disorders
0.653 0.347 0.000
L87 Transepidermal elimination disorders
0.653 0.347 0.000
L88 Pyoderma gangrenosum
0.653 0.347 0.000
L86 Keratoderma in diseases classified elsewhere
0.653 0.347 0.000
L83 Acanthosis nigricans
0.653 0.347 0.000
L80 Vitiligo
0.653 0.347 0.000
O00-O08 Pregnancy with abortive outcome
0.653 0.347 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.652 0.348 0.000
E10.3 With ophthalmic complications
0.652 0.348 0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.652 0.348 0.000
S02 Fracture of skull and facial bones
0.652 0.348 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.651 0.349 0.000
E63 Other nutritional deficiencies
0.651 0.349 0.000
E56 Other vitamin deficiencies
0.651 0.349 0.000
E51 Thiamine deficiency
0.651 0.349 0.000
E50 Vitamin A deficiency
0.651 0.349 0.000
E60 Dietary zinc deficiency
0.651 0.349 0.000
E59 Dietary selenium deficiency
0.651 0.349 0.000
E58 Dietary calcium deficiency
0.651 0.349 0.000
E54 Ascorbic acid deficiency
0.651 0.349 0.000
E52 Niacin deficiency [pellagra]
0.651 0.349 0.000
E61 Deficiency of other nutrient elements
0.651 0.349 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.650 0.350 0.000
L60.5 Yellow nail syndrome
0.650 0.350 0.000
L60.4 Beau's lines
0.650 0.350 0.000
L60.3 Nail dystrophy
0.650 0.350 0.000
L60.2 Onychogryphosis
0.650 0.350 0.000
L60.1 Onycholysis
0.650 0.350 0.000
D69.6 Thrombocytopenia, unspecified
0.650 0.350 0.000
R06.2 Wheezing
0.650 0.350 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.649 0.350 0.000
H68 Eustachian salpingitis and obstruction
0.649 0.350 0.000
H67 Otitis media in diseases classified elsewhere
0.649 0.350 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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