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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77073981
log Bayes Factor = 11.9832
Chromosome 19   position 23,235,972  (GRCh37) Explore rs77073981 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
0.998 0.002 0.000
N17-N19 Renal failure
0.997 0.003 0.000
G90-G99 Other disorders of the nervous system
0.992 0.008 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.992 0.008 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.991 0.009 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.987 0.013 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.985 0.015 0.000
H02 Other disorders of eyelid
0.983 0.017 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.976 0.024 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.975 0.025 0.000
D60-D64 Aplastic and other anaemias
0.975 0.025 0.000
N17 Acute renal failure
0.974 0.026 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.971 0.029 0.000
D64 Other anaemias
0.968 0.032 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.967 0.033 0.000
D64.9 Anaemia, unspecified
0.964 0.036 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.959 0.041 0.000
N17.9 Acute renal failure, unspecified
0.958 0.042 0.000
G57 Mononeuropathies of lower limb
0.950 0.050 0.000
C51-C58 Malignant neoplasms of female genital organs
0.947 0.053 0.000
N18 Chronic renal failure
0.943 0.057 0.000
C79 Secondary malignant neoplasm of other sites
0.939 0.061 0.000
H30-H36 Disorders of choroid and retina
0.939 0.061 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.936 0.064 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.936 0.064 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.934 0.066 0.000
H02.3 Blepharochalasis
0.933 0.067 0.000
C78.2 Secondary malignant neoplasm of pleura
0.920 0.080 0.000
N19 Unspecified renal failure
0.919 0.081 0.000
G57.6 Lesion of plantar nerve
0.915 0.085 0.000
G93 Other disorders of brain
0.909 0.091 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.907 0.093 0.000
H02.8 Other specified disorders of eyelid
0.905 0.095 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.902 0.098 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.901 0.099 0.000
H50 Other strabismus
0.898 0.102 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.895 0.105 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.894 0.106 0.000
C77.0 Lymph nodes of head, face and neck
0.894 0.106 0.000
C56 Malignant neoplasm of ovary
0.894 0.106 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.890 0.110 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.890 0.110 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.889 0.111 0.000
G54 Nerve root and plexus disorders
0.887 0.113 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.885 0.115 0.000
R00 Abnormalities of heart beat
0.885 0.115 0.000
N76 Other inflammation of vagina and vulva
0.884 0.116 0.000
C34 Malignant neoplasm of bronchus and lung
0.884 0.116 0.000
N18.3 Chronic kidney disease, stage 3
0.876 0.124 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.874 0.126 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.869 0.131 0.000
E10-E14 Diabetes mellitus
0.866 0.134 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.864 0.136 0.000
R94 Abnormal results of function studies
0.860 0.140 0.000
R41.0 Disorientation, unspecified
0.860 0.140 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.856 0.144 0.000
S60-S69 Injuries to the wrist and hand
0.855 0.145 0.000
H34 Retinal vascular occlusions
0.854 0.146 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.853 0.147 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.852 0.148 0.000
C78.0 Secondary malignant neoplasm of lung
0.851 0.149 0.000
C77.5 Intrapelvic lymph nodes
0.850 0.150 0.000
Chapter VIII Diseases of the ear and mastoid process
0.848 0.152 0.000
N70 Salpingitis and oophoritis
0.844 0.156 0.000
R94.5 Abnormal results of liver function studies
0.844 0.156 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.843 0.157 0.000
N25-N29 Other disorders of kidney and ureter
0.841 0.158 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.841 0.159 0.000
G95 Other diseases of spinal cord
0.841 0.159 0.000
C77.1 Intrathoracic lymph nodes
0.836 0.164 0.000
H35 Other retinal disorders
0.835 0.165 0.000
N75 Diseases of Bartholin's gland
0.833 0.167 0.000
G30-G32 Other degenerative diseases of the nervous system
0.833 0.167 0.000
E10 Insulin-dependent diabetes mellitus
0.833 0.167 0.000
R00.0 Tachycardia, unspecified
0.832 0.168 0.000
H52 Disorders of refraction and accommodation
0.832 0.168 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.829 0.171 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.822 0.178 0.000
N72 Inflammatory disease of cervix uteri
0.819 0.181 0.000
G40-G47 Episodic and paroxysmal disorders
0.819 0.181 0.000
R27 Other lack of coordination
0.817 0.183 0.000
N00-N08 Glomerular diseases
0.816 0.184 0.000
G93.3 Postviral fatigue syndrome
0.815 0.185 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.811 0.189 0.000
G51 Facial nerve disorders
0.810 0.190 0.000
R00.2 Palpitations
0.809 0.191 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.808 0.192 0.000
C80 Malignant neoplasm without specification of site
0.807 0.193 0.000
H01 Other inflammation of eyelid
0.807 0.193 0.000
R47-R49 Symptoms and signs involving speech and voice
0.805 0.195 0.000
H02.4 Ptosis of eyelid
0.804 0.196 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.803 0.197 0.000
G96 Other disorders of central nervous system
0.803 0.197 0.000
H53-H54 Visual disturbances and blindness
0.801 0.199 0.000
D45 Polycythaemia vera
0.799 0.201 0.000
R06 Abnormalities of breathing
0.799 0.201 0.000
H02.0 Entropion and trichiasis of eyelid
0.799 0.201 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.797 0.202 0.000
H34.8 Other retinal vascular occlusions
0.795 0.205 0.000
H36 Retinal disorders in diseases classified elsewhere
0.794 0.206 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.792 0.208 0.000
C34.9 Bronchus or lung, unspecified
0.792 0.208 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.788 0.212 0.000
S70-S79 Injuries to the hip and thigh
0.784 0.216 0.000
R04 Haemorrhage from respiratory passages
0.784 0.216 0.000
N18.4 Chronic kidney disease, stage 4
0.782 0.218 0.000
C77.2 Intra-abdominal lymph nodes
0.776 0.224 0.000
H10-H13 Disorders of conjunctiva
0.775 0.225 0.000
C44 Other malignant neoplasms of skin
0.775 0.225 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.773 0.227 0.000
H50.0 Convergent concomitant strabismus
0.772 0.228 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.771 0.229 0.000
C34.3 Lower lobe, bronchus or lung
0.767 0.233 0.000
G54.9 Nerve root and plexus disorder, unspecified
0.766 0.234 0.000
E10.4 With neurological complications
0.765 0.235 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.763 0.237 0.000
C77.8 Lymph nodes of multiple regions
0.763 0.237 0.000
G93.0 Cerebral cysts
0.761 0.239 0.000
Q60-Q64 Congenital malformations of the urinary system
0.758 0.242 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.757 0.243 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.757 0.243 0.000
R27.0 Ataxia, unspecified
0.757 0.243 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.755 0.245 0.000
C79.6 Secondary malignant neoplasm of ovary
0.754 0.246 0.000
H43-H45 Disorders of vitreous body and globe
0.754 0.246 0.000
H50.9 Strabismus, unspecified
0.753 0.247 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.749 0.250 0.000
O47 False labour
0.750 0.250 0.000
R44.1 Visual hallucinations
0.749 0.251 0.000
C77.9 Lymph node, unspecified
0.749 0.251 0.000
Chapter XXII Codes for special purposes
0.748 0.252 0.000
D80-D89 Certain disorders involving the immune mechanism
0.746 0.253 0.000
D61 Other aplastic anaemias
0.744 0.255 0.000
G50 Disorders of trigeminal nerve
0.744 0.256 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.744 0.256 0.000
G91 Hydrocephalus
0.744 0.256 0.000
H50.1 Divergent concomitant strabismus
0.743 0.257 0.000
D46 Myelodysplastic syndromes
0.743 0.257 0.000
Chapter XX External causes of morbidity and mortality
0.743 0.257 0.000
C54 Malignant neoplasm of corpus uteri
0.742 0.258 0.000
N18.0 End-stage renal disease
0.742 0.258 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.742 0.258 0.000
N76.3 Subacute and chronic vulvitis
0.742 0.258 0.000
G20-G26 Extrapyramidal and movement disorders
0.741 0.258 0.000
H02.6 Xanthelasma of eyelid
0.741 0.259 0.000
N60-N64 Disorders of breast
0.741 0.259 0.000
N75.0 Cyst of Bartholin's gland
0.741 0.259 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.740 0.260 0.000
N76.0 Acute vaginitis
0.738 0.262 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.738 0.262 0.000
R25 Abnormal involuntary movements
0.737 0.263 0.000
H52.1 Myopia
0.734 0.266 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.734 0.266 0.000
E20-E35 Disorders of other endocrine glands
0.733 0.267 0.000
G54.4 Lumbosacral root disorders, not elsewhere classified
0.732 0.268 0.000
N71 Inflammatory disease of uterus, except cervix
0.730 0.270 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.729 0.271 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.729 0.271 0.000
D47.1 Chronic myeloproliferative disease
0.727 0.273 0.000
G57.8 Other mononeuropathies of lower limb
0.727 0.273 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.727 0.273 0.000
D55-D59 Haemolytic anaemias
0.727 0.273 0.000
R06.8 Other and unspecified abnormalities of breathing
0.727 0.273 0.000
R45 Symptoms and signs involving emotional state
0.726 0.274 0.000
C34.2 Middle lobe, bronchus or lung
0.725 0.274 0.000
G58 Other mononeuropathies
0.725 0.274 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.725 0.275 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.724 0.276 0.000
C78.7 Secondary malignant neoplasm of liver
0.724 0.276 0.000
H90-H95 Other disorders of ear
0.724 0.276 0.000
C79.2 Secondary malignant neoplasm of skin
0.723 0.277 0.000
N18.9 Chronic renal failure, unspecified
0.723 0.277 0.000
E14 Unspecified diabetes mellitus
0.723 0.277 0.000
S62 Fracture at wrist and hand level
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
G56 Mononeuropathies of upper limb
0.716 0.284 0.000
R26 Abnormalities of gait and mobility
0.716 0.284 0.000
G70-G73 Diseases of myoneural junction and muscle
0.716 0.284 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.714 0.286 0.000
D48.5 Skin
0.714 0.286 0.000
Chapter I Certain infectious and parasitic diseases
0.714 0.286 0.000
R44.3 Hallucinations, unspecified
0.713 0.287 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.711 0.289 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.711 0.289 0.000
G90 Disorders of autonomic nervous system
0.711 0.289 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.711 0.289 0.000
G92 Toxic encephalopathy
0.711 0.289 0.000
H05 Disorders of orbit
0.711 0.289 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.711 0.289 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.711 0.289 0.000
G47 Sleep disorders
0.711 0.289 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.711 0.289 0.000
H04 Disorders of lachrymal system
0.710 0.290 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.710 0.290 0.000
G52 Disorders of other cranial nerves
0.710 0.290 0.000
D48.1 Connective and other soft tissue
0.710 0.290 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.708 0.292 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.708 0.292 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.708 0.292 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.707 0.292 0.000
C32 Malignant neoplasm of larynx
0.706 0.294 0.000
N18.2 Chronic kidney disease, stage 2
0.705 0.295 0.000
D62 Acute posthaemorrhagic anaemia
0.705 0.295 0.000
H00 Hordeolum and chalazion
0.705 0.295 0.000
H02.7 Other degenerative disorders of eyelid and periocular area
0.705 0.295 0.000
H02.5 Other disorders affecting eyelid function
0.705 0.295 0.000
H02.2 Lagophthalmos
0.705 0.295 0.000
N70.1 Chronic salpingitis and oophoritis
0.703 0.297 0.000
D68 Other coagulation defects
0.702 0.298 0.000
D69 Purpura and other haemorrhagic conditions
0.702 0.298 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.702 0.298 0.000
H55-H59 Other disorders of eye and adnexa
0.701 0.299 0.000
S64 Injury of nerves at wrist and hand level
0.701 0.299 0.000
R04.0 Epistaxis
0.700 0.300 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.699 0.301 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.699 0.301 0.000
N17.8 Other acute renal failure
0.698 0.302 0.000
N17.2 Acute renal failure with medullary necrosis
0.698 0.302 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.698 0.302 0.000
N17.0 Acute renal failure with tubular necrosis
0.698 0.302 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.696 0.304 0.000
N99-N99 Other disorders of the genitourinary system
0.695 0.304 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.695 0.305 0.000
E10.3 With ophthalmic complications
0.695 0.305 0.000
D64.8 Other specified anaemias
0.694 0.306 0.000
D64.4 Congenital dyserythropoietic anaemia
0.694 0.306 0.000
D64.3 Other sideroblastic anaemias
0.694 0.306 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.694 0.306 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.694 0.306 0.000
D64.0 Hereditary sideroblastic anaemia
0.694 0.306 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.694 0.306 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.694 0.306 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.694 0.306 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.694 0.306 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.694 0.306 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.693 0.307 0.000
O42 Premature rupture of membranes
0.691 0.309 0.000
Q50-Q56 Congenital malformations of genital organs
0.691 0.309 0.000
H36.0 Diabetic retinopathy
0.691 0.309 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.690 0.310 0.000
Q80-Q89 Other congenital malformations
0.689 0.310 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.689 0.311 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.689 0.311 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.689 0.311 0.000
H60-H62 Diseases of external ear
0.688 0.312 0.000
H51 Other disorders of binocular movement
0.688 0.312 0.000
H49 Paralytic strabismus
0.688 0.312 0.000
R06.4 Hyperventilation
0.687 0.313 0.000
C53 Malignant neoplasm of cervix uteri
0.686 0.314 0.000
G95.2 Cord compression, unspecified
0.686 0.314 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.686 0.314 0.000
N70.9 Salpingitis and oophoritis, unspecified
0.685 0.314 0.000
R47 Speech disturbances, not elsewhere classified
0.685 0.315 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.685 0.315 0.000
Chapter V Mental and behavioural disorders
0.685 0.315 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.685 0.315 0.000
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions
0.684 0.316 0.000
H53 Visual disturbances
0.683 0.317 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.682 0.318 0.000
G57.9 Mononeuropathy of lower limb, unspecified
0.681 0.319 0.000
G57.5 Tarsal tunnel syndrome
0.681 0.319 0.000
G57.4 Lesion of medial popliteal nerve
0.681 0.319 0.000
G57.3 Lesion of lateral popliteal nerve
0.681 0.319 0.000
G57.2 Lesion of femoral nerve
0.681 0.319 0.000
G57.1 Meralgia paraesthetica
0.681 0.319 0.000
G57.0 Lesion of sciatic nerve
0.681 0.319 0.000
R09.0 Asphyxia
0.680 0.319 0.000
G51.0 Bell's palsy
0.680 0.320 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.680 0.320 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.680 0.320 0.000
O36 Maternal care for other known or suspected foetal problems
0.680 0.320 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.679 0.321 0.000
C51 Malignant neoplasm of vulva
0.679 0.321 0.000
C58 Malignant neoplasm of placenta
0.679 0.321 0.000
C52 Malignant neoplasm of vagina
0.679 0.321 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.679 0.321 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.677 0.323 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.677 0.323 0.000
O43 Placental disorders
0.676 0.323 0.000
N18.8 Other chronic renal failure
0.676 0.324 0.000
N18.1 Chronic kidney disease, stage 1
0.676 0.324 0.000
H35.9 Retinal disorder, unspecified
0.674 0.326 0.000
G95.9 Disease of spinal cord, unspecified
0.674 0.326 0.000
H01.0 Blepharitis
0.674 0.326 0.000
C77.4 Inguinal and lower limb lymph nodes
0.673 0.326 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.673 0.327 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.673 0.327 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.673 0.327 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.673 0.327 0.000
H31 Other disorders of choroid
0.673 0.327 0.000
H30 Chorioretinal inflammation
0.673 0.327 0.000
H35.8 Other specified retinal disorders
0.672 0.328 0.000
O41 Other disorders of amniotic fluid and membranes
0.672 0.328 0.000
R46 Symptoms and signs involving appearance and behaviour
0.671 0.329 0.000
R43 Disturbances of smell and taste
0.671 0.329 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.671 0.329 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.671 0.329 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.671 0.329 0.000
C31 Malignant neoplasm of accessory sinuses
0.671 0.329 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.671 0.329 0.000
C37 Malignant neoplasm of thymus
0.671 0.329 0.000
C33 Malignant neoplasm of trachea
0.671 0.329 0.000
Chapter IX Diseases of the circulatory system
0.671 0.329 0.000
H02.9 Disorder of eyelid, unspecified
0.671 0.329 0.000
S66.8 Injury of other muscles and tendons at wrist and hand level
0.671 0.329 0.000
T90 Sequelae of injuries of head
0.670 0.330 0.000
C44.4 Skin of scalp and neck
0.670 0.330 0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere
0.670 0.330 0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere
0.670 0.330 0.000
C34.0 Main bronchus
0.669 0.331 0.000
Q00-Q07 Congenital malformations of the nervous system
0.668 0.332 0.000
G96.0 Cerebrospinal fluid leak
0.667 0.333 0.000
N76.8 Other specified inflammation of vagina and vulva
0.667 0.333 0.000
G62 Other polyneuropathies
0.665 0.335 0.000
E11 Non-insulin-dependent diabetes mellitus
0.665 0.335 0.000
O60-O75 Complications of labour and delivery
0.664 0.336 0.000
R06.2 Wheezing
0.664 0.336 0.000
C07 Malignant neoplasm of parotid gland
0.662 0.338 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.661 0.339 0.000
H02.1 Ectropion of eyelid
0.661 0.339 0.000
S69 Other and unspecified injuries of wrist and hand
0.659 0.341 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.657 0.343 0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level
0.656 0.344 0.000
N63 Unspecified lump in breast
0.656 0.344 0.000
H35.6 Retinal haemorrhage
0.654 0.345 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.654 0.346 0.000
G93.8 Other specified disorders of brain
0.651 0.348 0.000
G93.7 Reye's syndrome
0.651 0.348 0.000
G93.5 Compression of brain
0.651 0.348 0.000
G93.4 Encephalopathy, unspecified
0.651 0.348 0.000
G93.2 Benign intracranial hypertension
0.651 0.348 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.651 0.348 0.000
E10.2 With renal complications
0.651 0.348 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.651 0.349 0.000
E40-E46 Malnutrition
0.651 0.349 0.000
C43 Malignant melanoma of skin
0.650 0.350 0.000
H18 Other disorders of cornea
0.649 0.351 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.649 0.351 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.648 0.352 0.000
N76.2 Acute vulvitis
0.647 0.353 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.647 0.353 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.647 0.353 0.000
Q35-Q37 Cleft lip and cleft palate
0.647 0.353 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.647 0.353 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.647 0.353 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.647 0.353 0.000
T79-T79 Certain early complications of trauma
0.646 0.354 0.000
O85-O92 Complications predominantly related to the puerperium
0.646 0.354 0.000
H65-H75 Diseases of middle ear and mastoid
0.646 0.354 0.000
S72 Fracture of femur
0.646 0.354 0.000
N76.4 Abscess of vulva
0.644 0.355 0.000
O40 Polyhydramnios
0.644 0.356 0.000
H50.8 Other specified strabismus
0.644 0.356 0.000
H50.6 Mechanical strabismus
0.644 0.356 0.000
H50.5 Heterophoria
0.644 0.356 0.000
H50.4 Other and unspecified heterotropia
0.644 0.356 0.000
H50.3 Intermittent heterotropia
0.644 0.356 0.000
H50.2 Vertical strabismus
0.644 0.356 0.000
Q61 Cystic kidney disease
0.644 0.356 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.641 0.358 0.000
G56.2 Lesion of ulnar nerve
0.641 0.359 0.000
S70 Superficial injury of hip and thigh
0.640 0.360 0.000
H35.4 Peripheral retinal degeneration
0.640 0.360 0.000
E16 Other disorders of pancreatic internal secretion
0.640 0.360 0.000
G31.8 Other specified degenerative diseases of nervous system
0.638 0.362 0.000
G93.9 Disorder of brain, unspecified
0.638 0.362 0.000
R41.2 Retrograde amnesia
0.638 0.362 0.000
R41.1 Anterograde amnesia
0.638 0.362 0.000
E10.9 Without complications
0.638 0.362 0.000
O80-O84 Delivery
0.637 0.363 0.000
N73 Other female pelvic inflammatory diseases
0.636 0.363 0.000
O30 Multiple gestation
0.636 0.364 0.000
C44.5 Skin of trunk
0.636 0.364 0.000
H52.3 Anisometropia and aniseikonia
0.636 0.364 0.000
G93.6 Cerebral oedema
0.636 0.364 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.636 0.364 0.000
G54.8 Other nerve root and plexus disorders
0.636 0.364 0.000
G54.7 Phantom limb syndrome without pain
0.636 0.364 0.000
G54.6 Phantom limb syndrome with pain
0.636 0.364 0.000
G54.5 Neuralgic amyotrophy
0.636 0.364 0.000
G54.3 Thoracic root disorders, not elsewhere classified
0.636 0.364 0.000
G54.2 Cervical root disorders, not elsewhere classified
0.636 0.364 0.000
G54.1 Lumbosacral plexus disorders
0.636 0.364 0.000
G54.0 Brachial plexus disorders
0.636 0.364 0.000
H46 Optic neuritis
0.636 0.364 0.000
T33-T35 Frostbite
0.635 0.365 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.635 0.365 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.635 0.365 0.000
T00-T07 Injuries involving multiple body regions
0.635 0.365 0.000
S10-S19 Injuries to the neck
0.635 0.365 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.634 0.366 0.000
N28.8 Other specified disorders of kidney and ureter
0.634 0.366 0.000
N76.6 Ulceration of vulva
0.634 0.366 0.000
N76.5 Ulceration of vagina
0.634 0.366 0.000
N76.1 Subacute and chronic vaginitis
0.634 0.366 0.000
C34.8 Overlapping lesion of bronchus and lung
0.633 0.366 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.633 0.367 0.000
H91 Other hearing loss
0.631 0.369 0.000
D48.6 Breast
0.631 0.369 0.000
A30-A49 Other bacterial diseases
0.630 0.370 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.628 0.372 0.000
C09 Malignant neoplasm of tonsil
0.627 0.373 0.000
R94.4 Abnormal results of kidney function studies
0.627 0.373 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.626 0.374 0.000
O45 Premature separation of placenta [abruptio placentae]
0.623 0.377 0.000
O44 Placenta praevia
0.623 0.377 0.000
O33 Maternal care for known or suspected disproportion
0.623 0.377 0.000
O31 Complications specific to multiple gestation
0.623 0.377 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.622 0.378 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.621 0.378 0.000
E12 Malnutrition-related diabetes mellitus
0.621 0.379 0.000
D00-D09 In situ neoplasms
0.620 0.380 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.620 0.380 0.000
R44.2 Other hallucinations
0.619 0.381 0.000
R44.0 Auditory hallucinations
0.619 0.381 0.000
G47.3 Sleep apnoea
0.617 0.383 0.000
R94.8 Abnormal results of function studies of other organs and systems
0.616 0.383 0.000
R94.7 Abnormal results of other endocrine function studies
0.616 0.383 0.000
R94.6 Abnormal results of thyroid function studies
0.616 0.383 0.000
R94.2 Abnormal results of pulmonary function studies
0.616 0.383 0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses
0.616 0.383 0.000
R94.0 Abnormal results of function studies of central nervous system
0.616 0.383 0.000
G59.0 Diabetic mononeuropathy
0.616 0.384 0.000
S71 Open wound of hip and thigh
0.616 0.384 0.000
E50-E64 Other nutritional deficiencies
0.615 0.385 0.000
E14.3 With ophthalmic complications
0.615 0.385 0.000
H11 Other disorders of conjunctiva
0.614 0.386 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.614 0.386 0.000
D37.2 Small intestine
0.614 0.386 0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified
0.614 0.386 0.000
D48.7 Other specified sites
0.614 0.386 0.000
D48.4 Peritoneum
0.614 0.386 0.000
D48.3 Retroperitoneum
0.614 0.386 0.000
D48.2 Peripheral nerves and autonomic nervous system
0.614 0.386 0.000
D48.0 Bone and articular cartilage
0.614 0.386 0.000
S67 Crushing injury of wrist and hand
0.613 0.387 0.000
S65 Injury of blood vessels at wrist and hand level
0.613 0.387 0.000
S60 Superficial injury of wrist and hand
0.613 0.387 0.000
H35.3 Degeneration of macula and posterior pole
0.613 0.387 0.000
T92 Sequelae of injuries of upper limb
0.613 0.387 0.000
H34.9 Retinal vascular occlusion, unspecified
0.612 0.387 0.000
H34.1 Central retinal artery occlusion
0.612 0.387 0.000
H34.0 Transient retinal artery occlusion
0.612 0.387 0.000
C44.3 Skin of other and unspecified parts of face
0.612 0.388 0.000
D67 Hereditary factor IX deficiency
0.612 0.388 0.000
D66 Hereditary factor VIII deficiency
0.612 0.388 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.612 0.388 0.000
E10.1 With ketoacidosis
0.612 0.388 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.611 0.389 0.000
S62.5 Fracture of thumb
0.611 0.389 0.000
O48 Prolonged pregnancy
0.610 0.390 0.000
H04.1 Other disorders of lachrymal gland
0.610 0.390 0.000
R47.0 Dysphasia and aphasia
0.608 0.392 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.608 0.392 0.000
C45 Mesothelioma
0.607 0.392 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.607 0.393 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.607 0.393 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.607 0.393 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.607 0.393 0.000
O16 Unspecified maternal hypertension
0.606 0.394 0.000
H34.2 Other retinal artery occlusions
0.606 0.394 0.000
N70.0 Acute salpingitis and oophoritis
0.605 0.394 0.000
I05-I09 Chronic rheumatic heart diseases
0.605 0.395 0.000
H53.1 Subjective visual disturbances
0.605 0.395 0.000
C44.6 Skin of upper limb, including shoulder
0.605 0.395 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.604 0.396 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.604 0.396 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.603 0.397 0.000
N27 Small kidney of unknown cause
0.603 0.397 0.000
N25 Disorders resulting from impaired renal tubular function
0.603 0.397 0.000
N26 Unspecified contracted kidney
0.603 0.397 0.000
E13 Other specified diabetes mellitus
0.603 0.397 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.603 0.397 0.000
C13 Malignant neoplasm of hypopharynx
0.603 0.397 0.000
C11 Malignant neoplasm of nasopharynx
0.603 0.397 0.000
C10 Malignant neoplasm of oropharynx
0.603 0.397 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.603 0.397 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.603 0.397 0.000
C05 Malignant neoplasm of palate
0.603 0.397 0.000
C04 Malignant neoplasm of floor of mouth
0.603 0.397 0.000
C03 Malignant neoplasm of gum
0.603 0.397 0.000
C00 Malignant neoplasm of lip
0.603 0.397 0.000
C12 Malignant neoplasm of pyriform sinus
0.603 0.397 0.000
G95.8 Other specified diseases of spinal cord
0.603 0.397 0.000
G95.1 Vascular myelopathies
0.603 0.397 0.000
G95.0 Syringomyelia and syringobulbia
0.603 0.397 0.000
R27.8 Other and unspecified lack of coordination
0.602 0.398 0.000
Q43 Other congenital malformations of intestine
0.601 0.399 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.601 0.399 0.000
S90-S99 Injuries to the ankle and foot
0.598 0.401 0.000
H35.7 Separation of retinal layers
0.598 0.401 0.000
H35.5 Hereditary retinal dystrophy
0.598 0.401 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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